Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics

ABSTRACT

The invention provides isolated polypeptide and nucleic acid sequences derived from  Pseudomonas aeruginosa  that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is converted from U.S. provisional application Serial No. 60/074,788, filed Feb. 18, 1998 and U.S. provisional application Serial No. 60/094,190 filed Jul. 27, 1998.

FIELD OF THE INVENTION

The invention relates to isolated nucleic acids and polypeptides derived from Pseudomonas aeruginosa that are useful as molecular targets for diagnostics, prophylaxis and treatment of pathological conditions, as well as materials and methods for the diagnosis, prevention, and amelioration of pathological conditions resulting from bacterial infection.

BRIEF DESCRIPTION OF THE SEQUENCE LISTING

Incorporated herein by reference in its entirety is a Sequence Listing, comprising SEQ ID NO: 1 to SEQ ID NO: 33,142. The Sequence Listing is contained on a CD-ROM, three copies of which are filed, the Sequence Listing being in a computer-readable ASCII file named “Path9904.pto”, created on Oct. 20, 2000 and of 68,982,000 bytes in size, in IBM-PC Windows®NT v4.0 format.

BACKGROUND OF THE INVENTION

Pseudomonas aeruginosa (P. aeruginosa) is an aerobic, motile, gram-negative, rod. P. aeruginosa normally inhabits soil, water, and vegetation. Although it seldom causes disease in healthy people, P. aeruginosa is an opportunistic pathogen which accounts for ˜10% of all nosocomial infections (National Nosocomial Infection Survey report-Data Summary from October 1986-April 1996). P. aeruginosa is the most common pathogen affecting Cystic Fibrosis patients with 61% of the specimens culturing positive (Govan, J. R. W. and V. Deretic, 1996, Microbiol. Reviews, 60(3):530-574) as well as one of the two most common pathogens observed in intensive care units (Jarvis, W. R. et al., 1992, J. Antimicrob. Chemother., 29(a supp.):19-24). Mortality from some P. aeruginosa infections can be as high as 50%. Presently, P. aeruginosa infection can still be effectively controlled by antibiotics particularly using a combination of drugs. However, resistance to several of the common antibiotics has been shown and is particularly problematic in ICUs (Archibald, L. et al., 1997, Clin. Infectious Dis., 24(2):211-215; Fish, D. N., et al., 1995, Pharmacotherapy, 15(3):279-291). In addition, P. aeruginosa has already demonstrated mechanisms for acquiring plasmids containing antibiotic resistance genes (Jakoby, G. A. (1986), The bacteria, Vol. X, The biology of Pseudomonas, pp. 265-294, J. R. Sokach (ed.) Academic Press, London) and at present thare are no approved vaccines for Pseudomonas infection.

Like many other bacterial species, strain variability in P. aeruginosa is quite significant. Variability has been shown to occur by a number of different mechanisms, these include but are not limited to the integration into the genome of prophages (Zierdt, C. H. and P. J. Schmidt, 1964, J. Bacteriol. 87:1003-1010), the addition of the cytotoxin gene and pyocins from bacteriophages (Hayashi, T., et al., 1994, FEMS Microbiol. Lett. 122:239-244) and via transposons (Sinclair, M. I. and B. W. Holloway, 1982, J. Bacteriol. 151:569-579). Through this type of diversity, new pathogenic mechanisms have been incorporated into P. aeruginosa. These and other transitions such as the conversion to the mucoidy phenotype commonly seen in CF clearly illustrate the need for continued vigilance.

These concerns point to the need for diagnostic tools and therapeutics aimed at proper identification of strain and eradication of virulence. The design of vaccines that will limit the spread of infection and halt transfer of resistance factors is very desirable.

SUMMARY OF THE INVENTION

The present invention fulfills the need for diagnostic tools and therapeutics by providing bacterial-specific compositions and methods for detecting Pseudomonas species including P. aeruginosa, as well as compositions and methods useful for treating and preventing Pseudomonas infection, in particular, P. aeruginosa infection, in vertebrates including mammals.

The present invention encompasses isolated nucleic acids and polypeptides derived from P. aeruginosa that are useful as reagents for diagnosis of bacterial disease, components of effective antibacterial vaccines, and/or as targets for antibacterial drugs including anti-P. aeruginosa drugs. They can also be used to detect the presence of P. aeruginosa and other Pseudomonas species in a sample; and in screening compounds for the ability to interfere with the P. aeruginosa life cycle or to inhibit P. aeruginosa infection. They also has use as biocontrol agents for plants.

In one aspect, the invention features compositions of nucleic acids corresponding to entire coding sequences of P. aeruginosa proteins, including surface or secreted proteins or parts thereof, nucleic acids capable of binding mRNA from P. aeruginosa proteins to block protein translation, and methods for producing P. aeruginosa proteins or parts thereof using peptide synthesis and recombinant DNA techniques. This invention also features antibodies and nucleic acids useful as probes to detect P. aeruginosa infection. In addition, vaccine compositions and methods for protection against or treatment of infection by P. aeruginosa are within the scope of this invention.

The nucleotide sequences provided in SEQ ID NO: 1-SEQ ID NO: 16571, a fragment thereof, or a nucleotide sequence at least about 99.5% identical to a sequence contained within SEQ ID NO: 1-SEQ ID NO: 16571 may be “provided” in a variety of medias to facilitate use thereof. As used herein, “provided” refers to a manufacture, other than an isolated nucleic acid molecule, which contains a nucleotide sequence of the present invention, i.e., the nucleotide sequence provided in SEQ ID NO: 1-SEQ ID NO: 16571, a fragment thereof, or a nucleotide sequence at least about 99.5% identical to a sequence contained within SEQ ID NO: 1-SEQ ID NO: 16571. Uses for and methods for providing nucleotide sequences in a variety of media are well known in the art (see e.g., EPO Publication No. EP 0 756 006).

In one application of this embodiment, a nucleotide sequence of the present invention can be recorded on computer readable media. As used herein, “computer readable media” refers to any media which can be read and accessed directly by a computer. Such media include, but are not limited to: magnetic storage media, such as floppy discs, hard disc storage media, and magnetic tape; optical storage media such as CD-ROM; electrical storage media such as RAM and ROM; and hybrids of these categories such as magnetic/optical storage media. A person skilled in the art can readily appreciate how any of the presently known computer readable media can be used to create a manufacture comprising computer readable media having recorded thereon a nucleotide sequence of the present invention.

As used herein, “recorded” refers to a process for storing information on computer readable media. A person skilled in the art can readily adopt any of the presently known methods for recording information on computer readable media to generate manufactures comprising the nucleotide sequence information of the present invention.

A variety of data storage structures are available to a person skilled in the art for creating a computer readable media having recorded thereon a nucleotide sequence of the present invention. The choice of the data storage structure will generally be based on the means chosen to access the stored information. In addition, a variety of data processor programs and formats can be used to store the nucleotide sequence information of the present invention on computer readable media. The sequence information can be represented in a word processing text file, formatted in commercially-available software such as WordPerfect and Microsoft Word, or represented in the form of an ASCII file, stored in a database application, such as DB2, Sybase, Oracle, or the like. A person skilled in the art can readily adapt any number of data processor structuring formats (e.g. text file or database) in order to obtain computer readable media having recorded thereon the nucleotide sequence information of the present invention.

By providing the nucleotide sequence of SEQ ID NO: 1-SEQ ID NO: 16571, a fragment thereof, or a nucleotide sequence at least about 99.5% identical to SEQ ID NO: 1-SEQ ID NO: 16571 in computer readable form, a person skilled in the art can routinely access the coding sequence information for a variety of purposes. Computer software is publicly available which allows a person skilled in the art to access sequence information provided in a computer readable media. Examples of such computer software include programs of the “Staden Package”, “DNA Star”, “MacVector”, GCG “Wisconsin Package” (Genetics Computer Group, Madison, Wis.) and “NCBI Toolbox” (National Center For Biotechnology Information). Suitable programs are described, for example, in Martin J. Bishop, ed., Guide to Human Genome Computing, 2d Edition, Academic Press, San Diego, Calif. (1998); and Leonard F. Peruski, Jr., and Anne Harwood Peruski, The Internet and the New Biology: Tools for Genomic and Molecular Research, American Society for Microbiology, Washington, D.C. (1997).

Computer algorithms enable the identification of P. aeruginosa open reading frames (ORFs) within SEQ ID NO: 1-SEQ ID NO: 16571 which contain homology to ORFs or proteins from other organisms. Examples of such similarity-search algorithms include the BLAST [Altschul et al., J. Mol. Biol. 215:403-410 (1990)] and Smith-Waterman [Smith and Waterman (1981) Advances in Applied Mathematics, 2:482-489] search algorithms. Suitable search algorithms are described, for example, in Martin J. Bishop, ed., Guide to Human Genome Computing, 2d Edition, Academic Press, San Diego, Calif. (1998); and Leonard F. Peruski, Jr., and Anne Harwood Peruski, The Internet and the New Biology: Tools for Genomic and Molecular Research, American Society for Microbiology, Washington, D.C. (1997). Such algorithms are utilized on computer systems as exemplified below. The ORFs so identified represent protein encoding fragments within the P. aeruginosa genome and are useful in producing commercially important proteins such as enzymes used in fermentation reactions and in the production of commercially useful metabolites.

The present invention further provides systems, particularly computer-based systems, which contain the sequence information described herein. Such systems are designed to identify commercially important fragments of the P. aeruginosa genome. As used herein, “a computer-based system” refers to the hardware means, software means, and data storage means used to analyze the nucleotide sequence information of the present invention. The minimum hardware means of the computer-based systems of the present invention comprises a central processing unit (CPU), input means, output means, and data storage means. A person skilled in the art can readily appreciate that any one of the currently available computer-based systems is suitable for use in the present invention. The computer-based systems of the present invention comprise a data storage means having stored therein a nucleotide sequence of the present invention and the necessary hardware means and software means for supporting and implementing a search means. As used herein, “data storage means” refers to memory which can store nucleotide sequence information of the present invention, or a memory access means which can access manufactures having recorded thereon the nucleotide sequence information of the present invention.

As used herein, “search means” refers to one or more programs which are implemented on the computer-based system to compare a target sequence or target structural motif with the sequence information stored within the data storage means. Search means are used to identify fragments or regions of the P. aeruginosa genome which are similar to, or “match”, a particular target sequence or target motif. A variety of known algorithms are known in the art and have been disclosed publicly, and a variety of commercially available software for conducting homology-based similarity searches are available and can be used in the computer-based systems of the present invention. Examples of such software includes, but is not limited to, FASTA (GCG Wisconsin Package), Bic_SW (Compugen Bioccelerator), BLASTN2, BLASTP2, BLASTD2 (NCBI) and Motifs (GCG). Suitable software programs are described, for example, in Martin J. Bishop, ed., Guide to Human Genome Computing, 2d Edition, Academic Press, San Diego, Calif. (1998); and Leonard F. Peruski, Jr., and Anne Harwood Peruski, The Internet and the New Biology: Tools for Genomic and Molecular Research, American Society for Microbiology, Washington, D.C. (1997). A person skilled in the art can readily recognize that any one of the available algorithms or implementing software packages for conducting homology searches can be adapted for use in the present computer-based systems.

As used herein, a “target sequence” can be any DNA or amino acid sequence of six or more nucleotides or two or more amino acids. A person skilled in the art can readily recognize that the longer a target sequence is, the less likely a target sequence will be present as a random occurrence in the database. The most preferred sequence length of a target sequence is from about 10 to 100 amino acids or from about 30 to 300 nucleotide residues. However, it is well recognized that many genes are longer than 500 amino acids, or 1.5 kb in length, and that commercially important fragments of the P. aeruginosa genome, such as sequence fragments involved in gene expression and protein processing, will often be shorter than 30 nucleotides.

As used herein, “a target structural motif,” or “target motif,” refers to any rationally selected sequence or combination of sequences in which the sequence(s) are chosen based on a specific functional domain or three-dimensional configuration which is formed upon the folding of the target polypeptide. There are a variety of target motifs known in the art. Protein target motifs include, but are not limited to, enzymatic active sites, membrane-spanning regions, and signal sequences. Nucleic acid target motifs include, but are not limited to, promoter sequences, hairpin structures and inducible expression elements (protein binding sequences).

A variety of structural formats for the input and output means can be used to input and output the information in the computer-based systems of the present invention. A preferred format for an output means ranks fragments of the P. aeruginosa genome possessing varying degrees of homology to the target sequence or target motif. Such presentation provides a person skilled in the art with a ranking of sequences which contain various amounts of the target sequence or target motif and identifies the degree of homology contained in the identified fragment.

A variety of comparing means can be used to compare a target sequence or target motif with the data storage means to identify sequence fragments of the P. aeruginosa genome. In the present examples, implementing software which implement the BLASTP2 and bic_SW algorithms (Altschul et al., J Mol. Biol. 215:403-410 (1990); Compugen Biocellerator) was used to identify open reading frames within the P. aeruginosa genome. A person skilled in the art can readily recognize that any one of the publicly available homology search programs can be used as the search means for the computer-based systems of the present invention. Suitable programs are described, for example, in Martin J. Bishop, ed., Guide to Human Genome Computing, 2d Edition, Academic Press, San Diego, Calif. (1998); and Leonard F. Peruski, Jr., and Anne Harwood Peruski, The Internet and the New Biology: Tools for Genomic and Molecular Research, American Society for Microbiology, Washington, D.C. (1997).

The invention features P. aeruginosa polypeptides, preferably a substantially pure preparation of a P. aeruginosa polypeptide, or a recombinant P. aeruginosa polypeptide. In preferred embodiments: the polypeptide has biological activity; the polypeptide has an amino acid sequence at least about 60%, 70%, 80%, 90%, 95%, 98%, or 99% identical to an amino acid sequence of the invention contained in the Sequence Listing, preferably it has about 65% sequence identity with an amino acid sequence of the invention contained in the Sequence Listing, and most preferably it has about 92% to about 99% sequence identity with an amino acid sequence of the invention contained in the Sequence Listing; the polypeptide has an amino acid sequence essentially the same as an amino acid sequence of the invention contained in the Sequence Listing; the polypeptide is at least about 5, 10, 20, 50, 100, or 150 amino acid residues in length; the polypeptide includes at least about 5, preferably at least about 10, more preferably at least about 20, more preferably at least about 50, 100, or 150 contiguous amino acid residues of the invention contained in the Sequence Listing. In yet another preferred embodiment, the amino acid sequence which differs in sequence identity by about 7% to about 8% from the P. aeruginosa amino acid sequences of the invention contained in the Sequence Listing is also encompassed by the invention.

In preferred embodiments: the P. aeruginosa polypeptide is encoded by a nucleic acid of the invention contained in the Sequence Listing, or by a nucleic acid having at least about 60%, 70%, 80%, 90%, 95%, 98%, or 99% homology with a nucleic acid of the invention contained in the Sequence Listing.

In a preferred embodiment, the subject P. aeruginosa polypeptide differs in amino acid sequence at 1, 2, 3, 5, 10 or more residues from a sequence of the invention contained in the Sequence Listing. The differences, however, are such that the P. aeruginosa polypeptide exhibits a P. aeruginosa biological activity, e.g., the P. aeruginosa polypeptide retains a biological activity of a naturally occurring P. aeruginosa enzyme.

In preferred embodiments, the polypeptide includes all or a fragment of an amino acid sequence of the invention contained in the Sequence Listing; fused, in reading frame, to additional amino acid residues, preferably to residues encoded by genomic DNA 5′ or 3′ to the genomic DNA which encodes a sequence of the invention contained in the Sequence Listing.

In yet other preferred embodiments, the P. aeruginosa polypeptide is a recombinant fusion protein having a first P. aeruginosa polypeptide portion and a second polypeptide portion, e.g., a second polypeptide portion having an amino acid sequence unrelated to P. aeruginosa. The second polypeptide portion can be, e.g., any of glutathione-S-transferase, a DNA binding domain, or a polymerase activating domain. In preferred embodiment the fusion protein can be used in a two-hybrid assay.

Polypeptides of the invention include those which arise as a result of alternative transcription events, alternative RNA splicing events, and alternative translational and postranslational events.

In a preferred embodiment, the encoded P. aeruginosa polypeptide differs (e.g., by amino acid substitution, addition or deletion of at least one amino acid residue) in amino acid sequence at 1, 2, 3, 5, 10 or more residues, from a sequence of the invention contained in the Sequence Listing. The differences, however, are such that: the P. aeruginosa encoded polypeptide exhibits a P. aeruginosa biological activity, e.g., the encoded P. aeruginosa enzyme retains a biological activity of a naturally occurring P. aeruginosa.

In preferred embodiments, the encoded polypeptide includes all or a fragment of an amino acid sequence of the invention contained in the Sequence Listing; fused, in reading frame, to additional amino acid residues, preferably to residues encoded by genomic DNA 5′ or 3′ to the genomic DNA which encodes a sequence of the invention contained in the Sequence Listing.

The P. aeruginosas strain from which the nucleotide sequences of the invention have been sequenced was deposited on Jul. 18, 1997 in the American Type Culture Collection (ATCC #202004) as strain 19804.

Included in the invention are: allelic variations; natural mutants; induced mutants; proteins encoded by DNA that hybridize under high or low stringency conditions to a nucleic acid which encodes a polypeptide of the invention contained in the Sequence Listing (for definitions of high and low stringency see Current Protocols in Molecular Biology, John Wiley & Sons, New York, 1989, 6.3.1-6.3.6, hereby incorporated by reference); and, polypeptides specifically bound by antisera to P. aeruginosa polypeptides, especially by antisera to an active site or binding domain of P. aeruginosa polypeptide. The invention also includes fragments, preferably biologically active fragments. These and other polypeptides are also referred to herein as P. aeruginosa polypeptide analogs or variants.

The invention further provides nucleic acids, e.g., RNA or DNA, encoding a polypeptide of the invention. This includes double stranded nucleic acids as well as coding and antisense single strands.

In preferred embodiments, the subject P. aeruginosa nucleic acid will include a transcriptional regulatory sequence, e.g. at least one of a transcriptional promoter or transcriptional enhancer sequence, operably linked to the P. aeruginosa gene sequence, e.g., to render the P. aeruginosa gene sequence suitable for expression in a recombinant host cell.

In yet a further preferred embodiment, the nucleic acid which encodes a P. aeruginosa polypeptide of the invention, hybridizes under stringent conditions to a nucleic acid probe corresponding to at least about 8 consecutive nucleotides of the invention contained in the Sequence Listing; more preferably to at least about 12 consecutive nucleotides of the invention contained in the Sequence Listing; more preferably to at least about 20 consecutive nucleotides of the invention contained in the Sequence Listing; more preferably still to at least about 40 consecutive nucleotides of the invention contained in the Sequence Listing.

In another aspect, the invention provides a substantially pure nucleic acid having a nucleotide sequence which encodes a P. aeruginosa polypeptide. In preferred embodiments: the encoded polypeptide has biological activity; the encoded polypeptide has an amino acid sequence at least about 60%, 70%, 80%, 90%, 95%, 98%, or 99% homologous to an amino acid sequence of the invention contained in the Sequence Listing; the encoded polypeptide has an amino acid sequence essentially the same as an amino acid sequence of the invention contained in the Sequence Listing; the encoded polypeptide is at least about 5, 10, 20, 50, 100, or 150 amino acids in length; the encoded polypeptide comprises at least about 5, preferably at least about 10, more preferably at least about 20, still more preferably at least about 50, 100, or 150 contiguous amino acids of the invention contained in the Sequence Listing.

In another aspect, the invention encompasses: a vector including a nucleic acid which encodes a P. aeruginosa polypeptide or a P. aeruginosa polypeptide variant as described herein; a host cell transfected with the vector; and a method of producing a recombinant P. aeruginosa polypeptide or P. aeruginosa polypeptide variant; including culturing the cell, e.g., in a cell culture medium, and isolating an P. aeruginosa or P. aeruginosa polypeptide variant, e.g., from the cell or from the cell culture medium.

One embodiment of the invention is directed to substantially isolated nucleic acids. Nucleic acids of the invention include sequences comprising at least about 8 nucleotides in length, more preferably at least about 12 nucleotides in length, even more preferably at least about 15-20 nucleotides in length, that correspond to a subsequence of any one of SEQ ID NO: 1-SEQ ID NO: 16571 or complements thereof. Alternatively, the nucleic acids comprise sequences contained within any ORF (open reading frame), including a complete protein-coding sequence, of which any of SEQ ID NO: 1-SEQ ID NO: 16571 forms a part. The invention encompasses sequence-conservative variants and function-conservative variants of these sequences. The nucleic acids may be DNA, RNA, DNA/RNA duplexes, protein-nucleic acid (PNA), or derivatives thereof.

In another aspect, the invention features, a purified recombinant nucleic acid having at least about 50%, 60%, 70%, 80%, 90%, 95%, 98%, or 99% homology with a sequence of the invention contained in the Sequence Listing

The invention also encompasses recombinant DNA (including DNA cloning and expression vectors) comprising these P. aeruginosa-derived sequences; host cells comprising such DNA, including fungal, bacterial, yeast, plant, insect, and mammalian host cells; and methods for producing expression products comprising RNA and polypeptides encoded by the P. aeruginosa sequences. These methods are carried out by incubating a host cell comprising a P. aeruginosa-derived nucleic acid sequence under conditions in which the sequence is expressed. The host cell may be native or recombinant. The polypeptides can be obtained by (a) harvesting the incubated cells to produce a cell fraction and a medium fraction; and (b) recovering the P. aeruginosa polypeptide from the cell fraction, the medium fraction, or both. The polypeptides can also be made by in vitro translation.

In another aspect, the invention features nucleic acids capable of binding mRNA of P. aeruginosa. Such nucleic acid is capable of acting as antisense nucleic acid to control the translation of mRNA of P. aeruginosa. A further aspect features a nucleic acid which is capable of binding specifically to a P. aeruginosa nucleic acid. These nucleic acids are also referred to herein as complements and have utility as probes and as capture reagents.

In another aspect, the invention features an expression system comprising an open reading frame corresponding to P. aeruginosa nucleic acid. The nucleic acid further comprises a control sequence compatible with an intended host. The expression system is useful for making polypeptides corresponding to P. aeruginosa nucleic acid.

In another aspect, the invention encompasses: a vector including a nucleic acid which encodes a P. aeruginosa polypeptide or a P. aeruginosa polypeptide variant as described herein; a host cell transfected with the vector; and a method of producing a recombinant P. aeruginosa polypeptide or P. aeruginosa polypeptide variant; including culturing the cell, e.g., in a cell culture medium, and isolating the P. aeruginosa or P. aeruginosa polypeptide variant, e.g., from the cell or from the cell culture medium.

In yet another embodiment of the invention encompasses reagents for detecting bacterial infection, including P. aeruginosa infection, which comprise at least one P. aeruginosa-derived nucleic acid defined by any one of SEQ ID NO: 1-SEQ ID NO: 16571, or sequence-conservative or function-conservative variants thereof. Alternatively, the diagnostic reagents comprise polypeptide sequences that are contained within any open reading frames (ORFs), including complete protein-coding sequences, contained within any of SEQ ID NO: 1-SEQ ID NO: 16571, or polypeptide sequences contained within any of SEQ ID NO: 16572-SEQ ID NO: 33142, or polypeptides of which any of the above sequences forms a part, or antibodies directed against any of the above peptide sequences or function-conservative variants and/or fragments thereof.

The invention further provides antibodies, preferably monoclonal antibodies, which specifically bind to the polypeptides of the invention. Methods are also provided for producing antibodies in a host animal. The methods of the invention comprise immunizing an animal with at least one P. aeruginosa-derived immunogenic component, wherein the immunogenic component comprises one or more of the polypeptides encoded by any one of SEQ ID NO: 1-SEQ ID NO: 16571 or sequence-conservative or function-conservative variants thereof; or polypeptides that are contained within any ORFs, including complete protein-coding sequences, of which any of SEQ ID NO: 1-SEQ ID NO: 16571 forms a part; or polypeptide sequences contained within any of SEQ ID NO: 16572-SEQ ID NO: 33142; or polypeptides of which any of SEQ ID NO: 16572-SEQ ID NO: 33142 forms a part. Host animals include any warm blooded animal, including without limitation mammals and birds. Such antibodies have utility as reagents for immunoassays to evaluate the abundance and distribution of P. aeruginosa-specific antigens.

In yet another aspect, the invention provides diagnostic methods for detecting P. aeruginosa antigenic components or anti-P. aeruginosa antibodies in a sample. P. aeruginosa antigenic components are detected by a process comprising: (i) contacting a sample suspected to contain a bacterial antigenic component with a bacterial-specific antibody, under conditions in which a stable antigen-antibody complex can form between the antibody and bacterial antigenic components in the sample; and (ii) detecting any antigen-antibody complex formed in step (i), wherein detection of an antigen-antibody complex indicates the presence of at least one bacterial antigenic component in the sample. In different embodiments of this method, the antibodies used are directed against a sequence encoded by any of SEQ ID NO: 1-SEQ ID NO: 16571 or sequence-conservative or function-conservative variants thereof, or against a polypeptide sequence contained in any of SEQ ID NO: 16572-SEQ ID NO: 33142 or function-conservative variants thereof.

In yet another aspect, the invention provides a method for detecting antibacterial-specific antibodies in a sample, which comprises: (i) contacting a sample suspected to contain antibacterial-specific antibodies with a P. aeruginosa antigenic component, under conditions in which a stable antigen-antibody complex can form between the P. aeruginosa antigenic component and antibacterial antibodies in the sample; and (ii) detecting any antigen-antibody complex formed in step (i), wherein detection of an antigen-antibody complex indicates the presence of antibacterial antibodies in the sample. In different embodiments of this method, the antigenic component is encoded by a sequence contained in any of SEQ ID NO: 1-SEQ ID NO: 16571 or sequence-conservative and function-conservative variants thereof, or is a polypeptide sequence contained in any of SEQ ID NO: 16572-SEQ ID NO: 33142 or function-conservative variants thereof.

In another aspect, the invention features a method of generating vaccines for immunizing an individual against P. aeruginosa. The method includes: immunizing a subject with a P. aeruginosa polypeptide, e.g., a surface or secreted polypeptide, or a combination of such peptides or active portion(s) thereof, and a pharmaceutically acceptable carrier. Such vaccines have therapeutic and prophylactic utilities.

In another aspect, the invention features a method of evaluating a compound, e.g. a polypeptide, e.g., a fragment of a host cell polypeptide, for the ability to bind a P. aeruginosa polypeptide. The method includes: contacting the Pseudomonas compound with a P. aeruginosa polypeptide and determining if the compound binds or otherwise interacts with a P. aeruginosa polypeptide. Compounds which bind P. aeruginosa are candidates as activators or inhibitors of the bacterial life cycle. These assays can be performed in vitro or in vivo.

In another aspect, the invention features a method of evaluating a compound, e.g. a polypeptide, e.g., a fragment of a host cell polypeptide, for the ability to bind a P. aeruginosa nucleic acid, e.g., DNA or RNA. The method includes: contacting the Pseudomonas compound with a P. aeruginosa nucleic acid and determining if the compound binds or otherwise interacts with a P. aeruginosa polypeptide. Compounds which bind P. aeruginosa are candidates as activators or inhibitors of the bacterial life cycle. These assays can be performed in vitro or in vivo.

A particularly preferred embodiment of the invention is directed to a method of screening test compounds for anti-bacterial activity, which method comprises: selecting as a target a bacterial specific sequence, which sequence is essential to the viability of a bacterial species; contacting a test compound with said target sequence; and selecting those test compounds which bind to said target sequence as potential anti-bacterial candidates. In one embodiment, the target sequence selected is specific to a single species, or even a single strain, i.e., the P. aeruginosa 19804. In a second embodiment, the target sequence is common to at least two species of bacteria. In a third embodiment, the target sequence is common to a family of bacteria. The target sequence may be a nucleic acid sequence or a polypeptide sequence. Methods employing sequences common to more than one species of microorganism may be used to screen candidates for broad spectrum anti-bacterial activity.

The invention also provides methods for preventing or treating disease caused by certain bacteria, including P. aeruginosa, which are carried out by administering to an animal in need of such treatment, in particular a warm-blooded vertebrate, including but not limited to birds and mammals, a compound that specifically inhibits or interferes with the function of a bacterial polypeptide or nucleic acid. In a particularly preferred embodiment, the mammal to be treated is human.

DETAILED DESCRIPTION OF THE INVENTION

The sequences of the present invention include the specific nucleic acid and amino acid sequences set forth in the Sequence Listing that forms a part of the present specification, and which are designated SEQ ID NO: 1-SEQ ID NO: 33142. Use of the terms “SEQ ID NO: 1-SEQ ID NO: 16571”, “SEQ ID NO: 16572-SEQ ID NO: 33142”, “the sequences depicted in Table 2”, and the like, is intended, for convenience, to refer to each individual SEQ ID NO individually, and is not intended to refer to the genus of these sequences unless such reference would be indicated. In other words, it is a shorthand for listing all of these sequences individually. The invention encompasses each sequence individually, as well as any combination thereof.

Definitions

“Nucleic acid” or “polynucleotide” as used herein refers to purine- and pyrimidine-containing polymers of any length, either polyribonucleotides or polydeoxyribonucleotides or mixed polyribo-polydeoxyribo nucleotides. This includes single- and double-stranded molecules, i.e., DNA—DNA, DNA-RNA and RNA—RNA hybrids, as well as “protein nucleic acids” (PNA) formed by conjugating bases to an amino acid backbone. This also includes nucleic acids containing modified bases.

A nucleic acid or polypeptide sequence that is “derived from” a designated sequence refers to a sequence that corresponds to a region of the designated sequence. For nucleic acid sequences, this encompasses sequences that are homologous or complementary to the sequence, as well as “sequence-conservative variants” and “function-conservative variants.” For polypeptide sequences, this encompasses “function-conservative variants.” Sequence-conservative variants are those in which a change of one or more nucleotides in a given codon position results in no alteration in the amino acid encoded at that position. Function-conservative variants are those in which a given amino acid residue in a polypeptide has been changed without altering the overall conformation and function of the native polypeptide, including, but not limited to, replacement of an amino acid with one having similar physico-chemical properties (such as, for example, acidic, basic, hydrophobic, and the like). “Function-conservative” variants also include any polypeptides that have the ability to elicit antibodies specific to a designated polypeptide.

An “P. aeruginosa-derived” nucleic acid or polypeptide sequence may or may not be present in other bacterial species, and may or may not be present in all P. aeruginosa strains. This term is intended to refer to the source from which the sequence was originally isolated. Thus, a P. aeruginosa-derived polypeptide, as used herein, may be used, e.g., as a target to screen for a broad spectrum antibacterial agent, to search for homologous proteins in other species of bacteria or in eukaryotic organisms such as bacteria humans, etc.

A purified or isolated polypeptide or a substantially pure preparation of a polypeptide are used interchangeably herein and, as used herein, mean a polypeptide that has been separated from other proteins, lipids, and nucleic acids with which it naturally occurs. Preferably, the polypeptide is also separated from substances, e.g., antibodies or gel matrix, e.g., polyacrylamide, which are used to purify it. Preferably, the polypeptide constitutes at least about 10, 20, 50 70, 80 or 95% dry weight of the purified preparation. Preferably, the preparation contains: sufficient polypeptide to allow protein sequencing; at least about 1, 10, or 100 mg of the polypeptide.

A purified preparation of cells refers to, in the case of plant or animal cells, an in vitro preparation of cells and not an entire intact plant or animal. In the case of cultured cells or microbial cells, it consists of a preparation of at least about 10% and more preferably 50% of the subject cells.

A purified or isolated or a substantially pure nucleic acid, e.g., a substantially pure DNA, (are terms used interchangeably herein) is a nucleic acid which is one or both of the following: not immediately contiguous with both of the coding sequences with which it is immediately contiguous (i.e., one at the 5′ end and one at the 3′ end) in the naturally-occurring genome of the organism from which the nucleic acid is derived; or which is substantially free of a nucleic acid with which it occurs in the organism from which the nucleic acid is derived. The term includes, for example, a recombinant DNA which is incorporated into a vector, e.g., into an autonomously replicating plasmid or virus, or into the genomic DNA of a prokaryote or eukaryote, or which exists as a separate molecule (e.g., a cDNA or a genomic DNA fragment produced by PCR or restriction endonuclease treatment) independent of other DNA sequences. Substantially pure DNA also includes a recombinant DNA which is part of a hybrid gene encoding additional P. aeruginosa DNA sequence.

A “contig” as used herein is a nucleic acid representing a continuous stretch of genomic sequence of an organism.

An “open reading frame”, also referred to herein as ORF, is a region of nucleic acid which encodes a polypeptide. This region may represent a portion of a coding sequence or a total sequence and can be determined from a stop to stop codon or from a start to stop codon.

As used herein, a “coding sequence” is a nucleic acid which is transcribed into messenger RNA and/or translated into a polypeptide when placed under the control of appropriate regulatory sequences. The boundaries of the coding sequence are determined by a translation start codon at the five prime terminus and a translation stop code at the three prime terminus. A coding sequence can include but is not limited to messenger RNA, synthetic DNA, and recombinant nucleic acid sequences.

A “complement” of a nucleic acid as used herein refers to an anti-parallel or antisense sequence that participates in Watson-Crick base-pairing with the original sequence.

A “gene product” is a protein or structural RNA which is specifically encoded by a gene.

As used herein, the term “probe” refers to a nucleic acid, peptide or other chemical entity which specifically binds to a molecule of interest. Probes are often associated with or capable of associating with a label. A label is a chemical moiety capable of detection. Typical labels comprise dyes, radioisotopes, luminescent and chemiluminescent moieties, fluorophores, enzymes, precipitating agents, amplification sequences, and the like. Similarly, a nucleic acid, peptide or other chemical entity which specifically binds to a molecule of interest and immobilizes such molecule is referred herein as a “capture ligand”. Capture ligands are typically associated with or capable of associating with a support such as nitro-cellulose, glass, nylon membranes, beads, particles and the like. The specificity of hybridization is dependent on conditions such as the base pair composition of the nucleotides, and the temperature and salt concentration of the reaction. These conditions are readily discernable to one of ordinary skill in the art using routine experimentation.

“Homologous” refers to the sequence similarity or sequence identity between two polypeptides or between two nucleic acid molecules. When a position in both of the two compared sequences is occupied by the same base or amino acid monomer subunit, e.g., if a position in each of two DNA molecules is occupied by adenine, then the molecules are homologous at that position. The percent of homology between two sequences is a function of the number of matching or homologous positions shared by the two sequences divided by the number of positions compared×100. For example, if 6 of 10 of the positions in two sequences are matched or homologous then the two sequences are 60% homologous. By way of example, the DNA sequences ATTGCC and TATGGC share 50% homology. Generally, a comparison is made when two sequences are aligned to give maximum homology.

Nucleic acids are hybridizable to each other when at least one strand of a nucleic acid can anneal to the other nucleic acid under defined stringency conditions. Stringency of hybridization is determined by: (a) the temperature at which hybridization and/or washing is performed; and (b) the ionic strength and polarity of the hybridization and washing solutions. Hybridization requires that the two nucleic acids contain complementary sequences; depending on the stringency of hybridization, however, mismatches may be tolerated. Typically, hybridization of two sequences at high stringency (such as, for example, in a solution of 0.5X SSC, at 65° C.) requires that the sequences be essentially completely homologous. Conditions of intermediate stringency (such as, for example, 2X SSC at 65° C.) and low stringency (such as, for example 2X SSC at 55° C.), require correspondingly less overall complementarity between the hybridizing sequences. (1X SSC is 0.15 M NaCl, 0.015 M Na citrate).

The terms peptides, proteins, and polypeptides are used interchangeably herein.

As used herein, the term “surface protein” refers to all surface accessible proteins, e.g. inner and outer membrane proteins, proteins adhering to the cell wall, and secreted proteins.

A polypeptide has P. aeruginosa biological activity if it has one, two and preferably more of the following properties: (1) if when expressed in the course of a P. aeruginosa infection, it can promote, or mediate the attachment of P. aeruginosa to a cell; (2) it has an enzymatic activity, structural or regulatory function characteristic of a P. aeruginosa protein; (3) or the gene which encodes it can rescue a lethal mutation in a P. aeruginosa gene. A polypeptide has biological activity if it is an antagonist, agonist, or super-agonist of a polypeptide having one of the above-listed properties.

A biologically active fragment or analog is one having an in vivo or in vitro activity which is characteristic of the P. aeruginosa polypeptides of the invention contained in the Sequence Listing, or of other naturally occurring P. aeruginosa polypeptides, e.g., one or more of the biological activities described herein. Especially preferred are fragments which exist in vivo, e.g., fragments which arise from post transcriptional processing or which arise from translation of alternatively spliced RNA's. Fragments include those expressed in native or endogenous cells as well as those made in expression systems, e.g., in CHO (Chinese Hamster Ovary) cells. Because peptides such as P. aeruginosa polypeptides often exhibit a range of physiological properties and because such properties may be attributable to different portions of the molecule, a useful P. aeruginosa fragment or P. aeruginosa analog is one which exhibits a biological activity in any biological assay for P. aeruginosa activity. Most preferably the fragment or analog possesses 10%, preferably 40%, more preferably 60%, 70%, 80% or 90% or greater of the activity of P. aeruginosa, in any in vivo or in vitro assay.

Analogs can differ from naturally occurring P. aeruginosa polypeptides in amino acid sequence or in ways that do not involve sequence, or both. Non-sequence modifications include changes in acetylation, methylation, phosphorylation, carboxylation, or glycosylation. Preferred analogs include P. aeruginosa polypeptides (or biologically active fragments thereof) whose sequences differ from the wild-type sequence by one or more conservative amino acid substitutions or by one or more non-conservative amino acid substitutions, deletions, or insertions which do not substantially diminish the biological activity of the P. aeruginosa polypeptide. Conservative substitutions typically include the substitution of one amino acid for another with similar characteristics, e.g., substitutions within the following groups: valine, glycine; glycine, alanine; valine, isoleucine, leucine; aspartic acid, glutamic acid; asparagine, glutamine; serine, threonine; lysine, arginine; and phenylalanine, tyrosine. Other conservative substitutions can be made in view of the table below.

TABLE 1 CONSERVATIVE AMINO ACID REPLACEMENTS For Amino Acid Code Replace with any of Alanine A D-Ala, Gly, beta-Ala, L-Cys, D-Cys Arginine R D-Arg, Lys, D-Lys, homo-Arg, D-homo-Arg, Met, Asparagine N D-Asn, Asp, D-Asp, Glu, D-Glu, Gln, D-Gln Aspartic Acid D D-Asp, D-Asn, Asn, Glu, D-Glu, Gln, D-Gln Cysteine C D-Cys, S-Me-Cys, Met, D-Met, Thr, D-Thr Glutamine Q D-Gln, Asn, D-Asn, Glu, D-Glu, Asp, D-Asp Glutamic Acid E D-Glu, D-Asp, Asp, Asn, D-Asn, Gln, D-Gln Glycine G Ala, D-Ala, Pro, D-Pro, β-Ala, Acp Isoleucine I D-Ile, Val, D-Val, Leu, D-Leu, Met, D-Met Leucine L D-Leu, Val, D-Val, Leu, D-Leu, Met, D-Met Lysine K D-Lys, Arg, D-Arg, homo-Arg, D-homo-Arg, Met, Methionine M D-Met, S-Me-Cys, Ile, D-IIe, Leu, D-Leu, Val, D- Phenylalanine F D-Phe, Tyr, D-Thr, L-Dopa, His, D-His, Trp, D- Proline P D-Pro, L-I-thioazolidine-4-carboxylic acid, D-or L- Serine S D-Ser, Thr, D-Thr, allo-Thr, Met, D-Met, Met(O), Threonine T D-Thr, Ser, D-Ser, allo-Thr, Met, D-Met, Met(O), Tyrosine Y D-Tyr, Phe, D-Phe, L-Dopa, His, D-His Valine V D-Val, Leu, D-Leu, Ile, D-Ile, Met, D-Met

Other analogs within the invention are those with modifications which increase peptide stability; such analogs may contain, for example, one or more non-peptide bonds (which replace the peptide bonds) in the peptide sequence. Also included are: analogs that include residues other than naturally occurring L-amino acids, e.g., D-amino acids or non-naturally occurring or synthetic amino acids, e.g., β or γ amino acids; and cyclic analogs.

As used herein, the term “fragment”, as applied to a P. aeruginosa analog, will ordinarily be at least about 20 residues, more typically at least about 40 residues, preferably at least about 60 residues in length. Fragments of P. aeruginosa polypeptides can be generated by methods known to those skilled in the art. The ability of an Pseudomonas fragment to exhibit a biological activity of P. aeruginosa polypeptide can be assessed by methods known to those skilled in the art as described herein. Also included are P. aeruginosa polypeptides containing residues that are not required for biological activity of the peptide or that result from alternative mRNA splicing or alternative protein processing events.

An “immunogenic component” as used herein is a moiety, such as a P. aeruginosa polypeptide, analog or fragment thereof, that is capable of eliciting a humoral and/or cellular immune response in a host animal.

An “antigenic component” as used herein is a moiety, such as a P. aeruginosa polypeptide, analog or fragment thereof, that is capable of binding to a specific antibody with sufficiently high affinity to form a detectable antigen-antibody complex.

The term “antibody” as used herein is intended to include fragments thereof which are specifically reactive with P. aeruginosa polypeptides.

As used herein, the term “cell-specific promoter” means a DNA sequence that serves as a promoter, i.e., regulates expression of a selected DNA sequence operably linked to the promoter, and which effects expression of the selected DNA sequence in specific cells of a tissue. The term also covers so-called “leaky” promoters, which regulate expression of a selected DNA primarily in one tissue, but cause expression in other tissues as well.

Misexpression, as used herein, refers to a non-wild type pattern of gene expression. It includes: expression at non-wild type levels, i.e., over or under expression; a pattern of expression that differs from wild type in terms of the time or stage at which the gene is expressed, e.g., increased or decreased expression (as compared with wild type) at a predetermined developmental period or stage; a pattern of expression that differs from wild type in terms of increased expression (as compared with wild type) in a predetermined cell type or tissue type; a pattern of expression that differs from wild type in terms of the splicing size, amino acid sequence, post-translational modification, or biological activity of the expressed polypeptide; a pattern of expression that differs from wild type in terms of the effect of an environmental stimulus or extracellular stimulus on expression of the gene, e.g., a pattern of increased or decreased expression (as compared with wild type) in the presence of an increase or decrease in the strength of the stimulus.

As used herein, “host cells” and other such terms denoting microorganisms or higher eukaryotic cell lines cultured as unicellular entities refers to cells which can become or have been used as recipients for a recombinant vector or other transfer DNA, and include the progeny of the original cell which has been transfected. It is understood by individuals skilled in the art that the progeny of a single parental cell may not necessarily be completely identical in genomic or total DNA compliment to the original parent, due to accident or deliberate mutation.

As used herein, the term “control sequence” refers to a nucleic acid having a base sequence which is recognized by the host organism to effect the expression of encoded sequences to which they are ligated. The nature of such control sequences differs depending upon the host organism; in prokaryotes, such control sequences generally include a promoter, ribosomal binding site, terminators, and in some cases operators; in eukaryotes, generally such control sequences include promoters, terminators and in some instances, enhancers. The term control sequence is intended to include at a minimum, all components whose presence is necessary for expression, and may also include additional components whose presence is advantageous, for example, leader sequences.

As used herein, the term “operably linked” refers to sequences joined or ligated to function in their intended manner. For example, a control sequence is operably linked to coding sequence by ligation in such a way that expression of the coding sequence is achieved under conditions compatible with the control sequence and host cell.

The “metabolism” of a substance, as used herein, means any aspect of the expression, function, action, or regulation of the substance. The metabolism of a substance includes modifications, e.g., covalent or non-covalent modifications of the substance. The metabolism of a substance includes modifications, e.g., covalent or non-covalent modification, the substance induces in other substances. The metabolism of a substance also includes changes in the distribution of the substance. The metabolism of a substance includes changes the substance induces in the distribution of other substances.

A “sample” as used herein refers to a biological sample, such as, for example, tissue or fluid isloated from an individual (including without limitation plasma, serum, cerebrospinal fluid, lymph, tears, saliva and tissue sections) or from in vitro cell culture constituents, as well as samples from the environment.

Technical and scientific terms used herein have the meanings commonly understood by one of ordinary skill in the art to which the present invention pertains, unless otherwise defined. Reference is made herein to various methodologies known to those of skill in the art. Publications and other materials setting forth such known methodologies to which reference is made are incorporated herein by reference in their entireties as though set forth in full. The practice of the invention will employ, unless otherwise indicated, conventional techniques of chemistry, molecular biology, microbiology, recombinant DNA, and immunology, which are within the skill of the art. Such techniques are explained fully in the literature. See e.g., Sambrook, Fritsch, and Maniatis, Molecular Cloning; Laboratory Manual 2nd ed. (1989); DNA Cloning, Volumes I and II (D. N Glover ed. 1985); Oligonucleotide Synthesis (M. J. Gait ed, 1984); Nucleic Acid Hybridization (B. D. Hames & S. J. Higgins eds. 1984); the series, Methods in Enzymology (Academic Press, Inc.), particularly Vol. 154 and Vol. 155 (Wu and Grossman, eds.); PCR-A Practical Approach (McPherson, Quirke, and Taylor, eds., 1991); Immunology, 2d Edition, 1989, Roitt et al., C.V. Mosby Company, and New York; Advanced Immunology, 2d Edition, 1991, Male et al., Grower Medical Publishing, New York.; DNA Cloning: A Practical Approach, Volumes I and II, 1985 (D. N. Glover ed.); Oligonucleotide Synthesis, 1984, (M. L. Gait ed); Transcription and Translation, 1984 (Hames and Higgins eds.); Animal Cell Culture, 1986 (R. I. Freshney ed.); Immobilized Cells and Enzymes, 1986 (IRL Press); Perbal, 1984, A Practical Guide to Molecular Cloning; and Gene Transfer Vectors for Mammalian Cells, 1987 (J. H. Miller and M. P. Calos eds., Cold Spring Harbor Laboratory);

Any suitable materials and/or methods known to those of skill can be utilized in carrying out the present invention: however preferred materials and/or methods are described. Materials, reagents and the like to which reference is made in the following description and examples are obtainable from commercial sources, unless otherwise noted.

P. aeruginosa Genomic Sequence

This invention provides nucleotide sequences of the genome of P. aeruginosa which thus comprises a DNA sequence library of P. aeruginosa genomic DNA. The detailed description that follows provides nucleotide sequences of P. aeruginosa, and also describes how the sequences were obtained and how ORFs and protein-coding sequences were identified. Also described are methods of using the disclosed P. aeruginosa sequences in methods including diagnostic and therapeutic applications. Furthermore, the library can be used as a database for identification and comparison of medically important sequences in this and other strains of P. aeruginosa.

To determine the genomic sequence of P. aeruginosa, DNA from strain 19804 of P. aeruginosa was isolated after Zymolyase digestion, sodium dodecyl sulfate lysis, potassium acetate precipitation, phenol:chloroform extraction and ethanol precipitation (Soll, D. R., T. Srikantha and S. R. Lockhart: Characterizing Developmentally Regulated Genes in P. aeruginosa, In, Microbial Genome Methods. K. W. Adolph, editor. CRC Press. New York. p 17-37.). DNA was sheared hydrodynamically using an HPLC (Oefner, et. al., 1996) to an insert size of 2000-3000 bp. After size fractionation by gel electrophoresis the fragments were blunt-ended, ligated to adapter oligonucleotides and cloned into the pGTC (Thomann) vector to construct a “shotgun” subclone library

DNA sequencing was achieved using established ABI sequencing methods on ABI377 automated DNA sequencers. The cloning and sequencing procedures are described in more detail in the Exemplification.

Individual sequence reads were assembled using PHRAP (P. Green, Abstracts of DOE Human Genome Program Contractor-Grantee Workshop V, January 1996, p.157). The average contig length was about 3-4 kb.

All subsequent steps were based on sequencing by ABI377 automated DNA sequencing methods. The cloning and sequencing procedures are described in more detail in the Exemplification.

A variety of approaches can be used to order the contigs so as to obtain a continuous sequence representing the entire P. aeruginosa genome. Synthetic oligonucleotides are designed that are complementary to sequences at the end of each contig. These oligonucleotides may be hybridized to libaries of P. aeruginosa genomic DNA in, for example, lambda phage vectors or plasmid vectors to identify clones that contain sequences corresponding to the junctional regions between individual contigs. Such clones are then used to isolate template DNA and the same oligonucleotides are used as primers in polymerase chain reaction (PCR) to amplify junctional fragments, the nucleotide sequence of which is then determined.

The P. aeruginosa sequences were analyzed for the presence of open reading frames (ORFs) comprising at least 180 nucleotides. As a result of the analysis of ORFs based on stop-to-stop codon reads, it should be understood that these ORFs may not correspond to the ORF of a naturally-occurring P. aeruginosa polypeptide. These ORFs may contain start codons which indicate the initiation of protein synthesis of a naturally-occurring P. aeruginosa polypeptide. Such start codons within the ORFs provided herein were identified by those of ordinary skill in the relevant art, and the resulting ORF and the encoded P. aeruginosa polypeptide is within the scope of this invention. For example, within the ORFs a codon such as AUG or GUG (encoding methionine or valine) which is part of the initiation signal for protein synthesis were identified and the portion of an ORF to corresponding to a naturally-occurring P. aeruginosa polypeptide was recognized. The predicted coding regions were defined by evaluating the coding potential of such sequences with the program GENEMARK™ (Borodovsky and McIninch, 1993, Comp. . 17:123).

Each predicted ORF amino acid sequence was compared with all sequences found in current GENBANK, SWISS-PROT, and PIR databases using the BLAST algorithm. BLAST identifies local alignments occurring by chance between the ORF sequence and the sequence in the databank (Altschal et al., 1990, L Mol. Biol. 215:403-410). Homologous ORFs (probabilities less than 10⁻⁵ by chance) and ORF's that are probably non-homologous (probabilities greater than 10⁻⁵ by chance) but have good codon usage were identified. Both homologous, sequences and non-homologous sequences with good codon usage, are likely to encode proteins and are encompassed by the invention.

P. aeruginosa Nucleic Acids

The present invention provides a library of P. aeruginosa_-derived nucleic acid sequences. The libraries provide probes, primers, and markers which are used as markers in epidemiological studies. The present invention also provides a library of P. aeruginosa-derived nucleic acid sequences which comprise or encode targets for therapeutic drugs.

The nucleic acids of this invention may be obtained directly from the DNA of the above referenced P. aeruginosa strain by using the polymerase chain reaction (PCR). See “PCR, A Practical Approach” (McPherson, Quirke, and Taylor, eds., IRL Press, Oxford, UK, 1991) for details about the PCR. High fidelity PCR is used to ensure a faithful DNA copy prior to expression. In addition, the authenticity of amplified products is verified by conventional sequencing methods. Clones carrying the desired sequences described in this invention may also be obtained by screening the libraries by means of the PCR or by hybridization of synthetic oligonucleotide probes to filter lifts of the library colonies or plaques as known in the art (see, e.g., Sambrook et al., Molecular Cloning, A Laboratory Manual 2nd edition, 1989, Cold Spring Harbor Press, NY).

It is also possible to obtain nucleic acids encoding P. aeruginosa polypeptides from a cDNA library in accordance with protocols herein described. A cDNA encoding a P. aeruginosa polypeptide can be obtained by isolating total mRNA from an appropriate strain. Double stranded cDNAs can then be prepared from the total mRNA. Subsequently, the cDNAs can be inserted into a suitable plasmid or viral (e.g., bacteriophage) vector using any one of a number of known techniques. Genes encoding P. aeruginosa polypeptides can also be cloned using established polymerase chain reaction techniques in accordance with the nucleotide sequence information provided by the invention. The nucleic acids of the invention can be DNA or RNA. Preferred nucleic acids of the invention are contained in the Sequence Listing.

The nucleic acids of the invention can also be chemically synthesized using standard techniques. Various methods of chemically synthesizing polydeoxynucleotides are known, including solid-phase synthesis which, like peptide synthesis, has been fully automated in commercially available DNA synthesizers (See e.g., Itakura et al. U.S. Pat. No. 4,598,049; Caruthers et al. U.S. Pat. No. 4,458,066; and Itakura U.S. Pat. Nos. 4,401,796 and 4,373,071, incorporated by reference herein).

In another example, DNA can be chemically synthesized using, e.g., the phosphoramidite solid support method of Matteucci et al., 1981, J. Am. Chem. Soc. 103:3185, the method of Yoo et al., 1989, J. Biol. Chem. 764:17078, or other well known methods. This can be done by sequentially linking a series of oligonucleotide cassettes comprising pairs of synthetic oligonucleotides, as described below.

Nucleic acids isolated or synthesized in accordance with features of the present invention are useful, by way of example, without limitation, as probes, primers, capture ligands, antisense genes and for developing expression systems for the synthesis of proteins and peptides corresponding to such sequences. As probes, primers, capture ligands and antisense agents, the nucleic acid normally consists of all or part (approximately twenty or more nucleotides for specificity as well as the ability to form stable hybridization products) of the nucleic acids of the invention contained in the Sequence Listing. These uses are described in further detail below.

Probes

A nucleic acid isolated or synthesized in accordance with the sequence of the invention contained in the Sequence Listing can be used as a probe to specifically detect P. aeruginosa. With the sequence information set forth in the present application, sequences of twenty or more nucleotides are identified which provide the desired inclusivity and exclusivity with respect to P. aeruginosa, and extraneous nucleic acids likely to be encountered during hybridization conditions. More preferably, the sequence will comprise at least about twenty to thirty nucleotides to convey stability to the hybridization product formed between the probe and the intended target molecules.

Sequences larger than 1000 nucleotides in length are difficult to synthesize but can be generated by recombinant DNA techniques. Individuals skilled in the art will readily recognize that the nucleic acids, for use as probes, can be provided with a label to facilitate detection of a hybridization product.

Nucleic acid isolated and synthesized in accordance with the sequence of the invention contained in the Sequence Listing can also be useful as probes to detect homologous regions (especially homologous genes) of other Pseudomonas species using appropriate stringency hybridization conditions as described herein.

Capture Ligand

For use as a capture ligand, the nucleic acid selected in the manner described above with respect to probes, can be readily associated with a support. The manner in which nucleic acid is associated with supports is well known. Nucleic acid having twenty or more nucleotides in a sequence of the invention contained in the Sequence Listing have utility to separate P. aeruginosa nucleic acid from one strain from the nucleic acid of other another strain as well as from other organisms. Nucleic acid having twenty or more nucleotides in a sequence of the invention contained in the Sequence Listing can also have utility to separate other Pseudomonas species from each other and from other organisms. Preferably, the sequence will comprise at least about twenty nucleotides to convey stability to the hybridization product formed between the probe and the intended target molecules. Sequences larger than 1000 nucleotides in length are difficult to synthesize but can be generated by recombinant DNA techniques.

Primers

Nucleic acid isolated or synthesized in accordance with the sequences described herein have utility as primers for the amplification of P. aeruginosa nucleic acid. These nucleic acids may also have utility as primers for the amplification of nucleic acids in other Pseudomonas species. With respect to polymerase chain reaction (PCR) techniques, nucleic acid sequences of ≧ about 10-15 nucleotides of the invention contained in the Sequence Listing have utility in conjunction with suitable enzymes and reagents to create copies of P. aeruginosa nucleic acid. More preferably, the sequence will comprise twenty or more nucleotides to convey stability to the hybridization product formed between the primer and the intended target molecules. Binding conditions of primers greater than 100 nucleotides are more difficult to control to obtain specificity. High fidelity PCR can be used to ensure a faithful DNA copy prior to expression. In addition, amplified products can be checked by conventional sequencing methods.

The copies can be used in diagnostic assays to detect specific sequences, including genes from P. aeruginosa and/or other Pseudomonas species. The copies can also be incorporated into cloning and expression vectors to generate polypeptides corresponding to the nucleic acid synthesized by PCR, as is described in greater detail herein.

The nucleic acids of the present invention find use as templates for the recombinant production of P. aeruginosa-derived peptides or polypeptides

Antisense

Nucleic acid or nucleic acid-hybridizing derivatives isolated or synthesized in accordance with the sequences described herein have utility as antisense agents to prevent the expression of P. aeruginosa genes. These sequences also have utility as antisense agents to prevent expression of genes of other Pseudomonas species.

In one embodiment, nucleic acid or derivatives corresponding to P. aeruginosa nucleic acids is loaded into a suitable carrier such as a liposome or bacteriophage for introduction into bacterial cells. For example, a nucleic acid having twenty or more nucleotides is capable of binding to bacteria nucleic acid or bacteria messenger RNA. Preferably, the antisense nucleic acid is comprised of 20 or more nucleotides to provide necessary stability of a hybridization product of non-naturally occurring nucleic acid and bacterial nucleic acid and/or bacterial messenger RNA. Nucleic acid having a sequence greater than 1000 nucleotides in length is difficult to synthesize but can be generated by recombinant DNA techniques. Methods for loading antisense nucleic acid in liposomes is known in the art as exemplified by U.S. Pat. No. 4,241,046 issued Dec. 23, 1980 to Papahadjopoulos et al.

The present invention encompasses isolated polypeptides and nucleic acids derived from P. aeruginosa that are useful as reagents for diagnosis of bacterial infection, components of effective anti-bacterial vaccines, and/or as targets for anti-bacterial drugs, including anti-P. aeruginosa drugs.

Expression of P. aeruginosa Nucleic Acids

Table 2, which is appended herewith and which forms part of the present specification, provides a list of open reading frames (ORFs) in both strands and a putative identification of the particular function of a polypeptide which is encoded by each ORF, based on the homology match (determined by the BLAST algorithm) of the predicted polypeptide with known proteins encoded by ORFs in other organisms. An ORF is a region of nucleic acid which encodes a polypeptide. This region may represent a portion of a coding sequence or a total sequence and was determined from stop to stop codons. Each contig represents a continuous stretch of the genomic sequence of the organism. The first column lists the ORF designation. The second and third columns list the SEQ ID numbers for the nucleic acid and amino acid sequences corresponding to each ORF, respectively. The fourth and fifth columns list the length of the nucleic acid ORF and the length of the amino acid ORF, respectively. The nucleotide sequence corresponding to each ORF begins at the first nucleotide immediately following a stop codon and ends at the nucleotide immediately preceding the next downstream stop codon in the same reading frame. It will be recognized by one skilled in the art that the natural translation initiation sites will correspond to ATG, GTG, or TTG codons located within the ORFs. The natural initiation sites depend not only on the sequence of a start codon but also on the context of the DNA sequence adjacent to the start codon. Usually, a recognizable ribosome binding site is found within 20 nucleotides upstream from the initiation codon. In some cases where genes are translationally coupled and coordinately expressed together in “operons”, ribosome binding sites are not present, but the initiation codon of a downstream gene may occur very close to, or overlap, the stop codon of the an upstream gene in the same operon. The correct start codons can be generally identified without undue experimentation because only a few codons need be tested. It is recognized that the translational machinery in bacteria initiates all polypeptide chains with the amino acid methionine, regardless of the sequence of the start codon. In some cases, polypeptides are post-translationally modified, resulting in an N-terminal amino acid other than methionine in vivo. The sixth and seventh columns provide metrics for assessing the likelihood of the homology match (determined by the BLASTP2 algorithm), as is known in the art, to the genes indicated in the tenth column when the designated ORF was compared against a non-redundant comprehensive protein database. Specifically, the sixth column represents the “Blast Score” for the match (a higher score is a better match), and the seventh column represents the “P-value” for the match (the probability that such a match can have occurred by chance; the lower the value, the more likely the match is valid). If a BLASTP2 score of less than 46 was obtained, no value is reported in the table the “P-value”. Column eight provides the name of the organism that was identified as having the closest homology match. The ninth column provides, where available, either a public database accession number or our own sequence name. The tenth column provides, where available, the Swissprot accession number (SP),(SP), the locus name (LN), the Organism (OR), Source of variant (SR), E.C. number (EC), the gene name (GN), the product name (PN), the Function Description (FN), Left End (LE), Right End (RE), Coding Direction (DI), and the description (DE) or notes (NT) for each ORF. Information that is not preceded by a code designation in the tenth column represents a description of the ORF. This information allows one of ordinary skill in the art to determine a potential use for each identified coding sequence and, as a result, allows to use the polypeptides of the present invention for commercial and industrial purposes.

Using the information provided in SEQ ID NO: 1-SEQ ID NO: 16571, SEQ ID NO: 16572-SEQ ID NO: 33142 and in Table 2 together with routine cloning and sequencing methods, one of ordinary skill in the art will be able to clone and sequence all the nucleic acid fragments of interest including open reading frames (ORFs) encoding a large variety proteins of P. aeruginosa.

Nucleic acid isolated or synthesized in accordance with the sequences described herein have utility to generate polypeptides. The nucleic acid of the invention exemplified in SEQ ID NO: 1-SEQ ID NO: 16571 and in Table 2 or fragments of said nucleic acid encoding active portions of P. aeruginosa polypeptides can be cloned into suitable vectors or used to isolate nucleic acid. The isolated nucleic acid is combined with suitable DNA linkers and cloned into a suitable vector.

The function of a specific gene or operon can be ascertained by expression in a bacterial strain under conditions where the activity of the gene product(s) specified by the gene or operon in question can be specifically measured. Alternatively, a gene product may be produced in large quantities in an expressing strain for use as an antigen, an industrial reagent, for structural studies, etc. This expression can be accomplished in a mutant strain which lacks the activity of the gene to be tested, or in a strain that does not produce the same gene product(s). This includes, but is not limited to, Eucaryotic species such as the yeast Saccharomyces cerevisiae, Methanobacterium strains or other Archaea, and Eubacteria such as E. coli, B. Subtilis, S. Aureus, S. Pneumonia or Pseudomonas putida. In some cases the expression host will utilize the natural P. aeruginosa promoter whereas in others, it will be necessary to drive the gene with a promoter sequence derived from the expressing organism (e.g., an E. coli beta-galactosidase promoter for expression in E. coli).

To express a gene product using the natural P. aeruginosa promoter, a procedure such as the following can be used. A restriction fragment containing the gene of interest, together with its associated natural promoter element and regulatory sequences (identified using the DNA sequence data) is cloned into an appropriate recombinant plasmid containing an origin of replication that functions in the host organism and an appropriate selectable marker. This can be accomplished by a number of procedures known to those skilled in the art. It is most preferably done by cutting the plasmid and the fragment to be cloned with the same restriction enzyme to produce compatible ends that can be ligated to join the two pieces together. The recombinant plasmid is introduced into the host organism by, for example, electroporation and cells containing the recombinant plasmid are identified by selection for the marker on the plasmid. Expression of the desired gene product is detected using an assay specific for that gene product.

In the case of a gene that requires a different promoter, the body of the gene (coding sequence) is specifically excised and cloned into an appropriate expression plasmid. This subcloning can be done by several methods, but is most easily accomplished by PCR amplification of a specific fragment and ligation into an expression plasmid after treating the PCR product with a restriction enzyme or exonuclease to create suitable ends for cloning.

A suitable host cell for expression of a gene can be any procaryotic or eucaryotic cell. Suitable methods for transforming host cells can be found in Sambrook et al. (Molecular Cloning: A Laboratory Manual, 2nd Edition, Cold Spring Harbor Laboratory Press (1989)), and other laboratory textbooks.

For example, a host cell transfected with a nucleic acid vector directing expression of a nucleotide sequence encoding a P. aeruginosa polypeptide can be cultured under appropriate conditions to allow expression of the polypeptide to occur. Suitable media for cell culture are well known in the art. Polypeptides of the invention can be isolated from cell culture medium, host cells, or both using techniques known in the art for purifying proteins including ion-exchange chromatography, gel filtration chromatography, ultrafiltration, electrophoresis, and immunoaffinity purification with antibodies specific for such polypeptides. Additionally, in many situations, polypeptides can be produced by chemical cleavage of a native protein (e.g., tryptic digestion) and the cleavage products can then be purified by standard techniques.

In the case of membrane bound proteins, these can be isolated from a host cell by contacting a membrane-associated protein fraction with a detergent forming a solubilized complex, where the membrane-associated protein is no longer entirely embedded in the membrane fraction and is solubilized at least to an extent which allows it to be chromatographically isolated from the membrane fraction. Chromatographic techniques which can be used in the final purification step are known in the art and include hydrophobic interaction, lectin affinity, ion exchange, dye affinity and immunoaffinity.

One strategy to maximize recombinant P. aeruginosa peptide expression in E. coli is to express the protein in a host bacteria with an impaired capacity to proteolytically cleave the recombinant protein (Gottesman, S., Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, Calif. (1990) 119-128). Another strategy would be to alter the nucleic acid encoding a P. aeruginosa peptide to be inserted into an expression vector so that the individual codons for each amino acid would be those preferentially utilized in highly expressed E. coli proteins (Wada et al., (1992) Nuc. Acids Res. 20:2111-2118). Such alteration of nucleic acids of the invention can be carried out by standard DNA synthesis techniques.

The nucleic acids of the invention can also be chemically synthesized using standard techniques. Various methods of chemically synthesizing polydeoxynucleotides are known, including solid-phase synthesis which, like peptide synthesis, has been fully automated in commercially available DNA synthesizers (See, e.g., Itakura et al. U.S. Pat. No. 4,598,049; Caruthers et al. U.S. Pat. No. 4,458,066; and Itakura U.S. Pat. Nos. 4,401,796 and 4,373,071, incorporated by reference herein).

The present invention provides a library of P. aeruginosa-derived nucleic acid sequences. The libraries provide probes, primers, and markers which can be used as markers in epidemiological studies. The present invention also provides a library of P. aeruginosa-derived nucleic acid sequences which comprise or encode targets for therapeutic drugs.

Nucleic acids comprising any of the sequences disclosed herein or sub-sequences thereof can be prepared by standard methods using the nucleic acid sequence information provided in SEQ ID NO: 1-SEQ ID NO:16571. For example, DNA can be chemically synthesized using, e.g., the phosphoramidite solid support method of Matteucci et al., 1981, J. Am. Chem. Soc. 103:3185, the method of Yoo et al., 1989, J. Biol. Chem. 764:17078, or other well known methods. This can be done by sequentially linking a series of oligonucleotide cassettes comprising pairs of synthetic oligonucleotides, as described below.

Of course, due to the degeneracy of the genetic code, many different nucleotide sequences can encode polypeptides having the amino acid sequences defined by SEQ ID NO: 16572-SEQ ID NO: 33142 or sub-sequences thereof. The codons can be selected for optimal expression in prokaryotic or eukaryotic systems. Such degenerate variants are also encompassed by this invention.

Insertion of nucleic acids (typically DNAs) encoding the polypeptides of the invention into a vector is easily accomplished when the termini of both the DNAs and the vector comprise compatible restriction sites. If this cannot be done, it may be necessary to modify the termini of the DNAs and/or vector by digesting back single-stranded DNA overhangs generated by restriction endonuclease cleavage to produce blunt ends, or to achieve the same result by filling in the single-stranded termini with an appropriate DNA polymerase.

Alternatively, any site desired may be produced, e.g., by ligating nucleotide sequences (linkers) onto the termini. Such linkers may comprise specific oligonucleotide sequences that define desired restriction sites. Restriction sites can also be generated by the use of the polymerase chain reaction (PCR). See, e.g., Saiki et al., 1988, Science 239:48. The cleaved vector and the DNA fragments may also be modified if required by homopolymeric tailing.

The nucleic acids of the invention may be isolated directly from cells. Alternatively, the polymerase chain reaction (PCR) method can be used to produce the nucleic acids of the invention, using either chemically synthesized strands or genomic material as templates. Primers used for PCR can be synthesized using the sequence information provided herein and can further be designed to introduce appropriate new restriction sites, if desirable, to facilitate incorporation into a given vector for recombinant expression.

The nucleic acids of the present invention may be flanked by natural P. aeruginosa regulatory sequences, or may be associated with heterologous sequences, including promoters, enhancers, response elements, signal sequences, polyadenylation sequences, introns, 5′- and 3′-noncoding regions, and the like. The nucleic acids may also be modified by many means known in the art. Non-limiting examples of such modifications include methylation, “caps”, substitution of one or more of the naturally occurring nucleotides with an analog, internucleotide modifications such as, for example, those with uncharged linkages (e.g., methyl phosphonates, phosphotriesters, phosphoroamidates, carbamates, etc.) and with charged linkages (e.g., phosphorothioates, phosphorodithioates, etc.). Nucleic acids may contain one or more additional covalently linked moieties, such as, for example, proteins (e.g., nucleases, toxins, antibodies, signal peptides, poly-L-lysine, etc.), intercalators (e.g., acridine, psoralen, etc.), chelators (e.g., metals, radioactive metals, iron, oxidative metals, etc.), and alkylators. PNAs are also included. The nucleic acid may be derivatized by formation of a methyl or ethyl phosphotriester or an alkyl phosphoramidate linkage. Furthermore, the nucleic acid sequences of the present invention may also be modified with a label capable of providing a detectable signal, either directly or indirectly. Exemplary labels include radioisotopes, fluorescent molecules, biotin, and the like.

The invention also provides nucleic acid vectors comprising the disclosed P. aeruginosa-derived sequences or derivatives or fragments thereof. A large number of vectors, including plasmid and bacterial vectors, have been described for replication and/or expression in a variety of eukaryotic and prokaryotic hosts, and may be used for cloning or protein expression.

The encoded P. aeruginosa polypeptides may be expressed by using many known vectors, such as pUC plasmids, pET plasmids (Novagen, Inc., Madison, Wis.), or pRSET or pREP (Invitrogen, San Diego, Calif.), and many appropriate host cells, using methods disclosed or cited herein or otherwise known to those skilled in the relevant art. The particular choice of vector/host is not critical to the practice of the invention.

Recombinant cloning vectors will often include one or more replication systems for cloning or expression, one or more markers for selection in the host, e.g. antibiotic resistance, and one or more expression cassettes. The inserted P. aeruginosa coding sequences may be synthesized by standard methods, isolated from natural sources, or prepared as hybrids, etc. Ligation of the P. aeruginosa coding sequences to transcriptional regulatory elements and/or to other amino acid coding sequences may be achieved by known methods. Suitable host cells may be transformed/transfected/infected as appropriate by any suitable method including electroporation, CaCl₂ mediated DNA uptake, bacterial infection, microinjection, microprojectile, or other established methods.

Appropriate host cells include bacteria, archebacteria, fungi, especially yeast, and plant and animal cells, especially mammalian cells. Of particular interest are P. aeruginosa, E. coli, B. Subtilis, Saccharomyces cerevisiae, Saccharomyces carlsbergensis, Schizosaccharomyces pombi, SF9 cells, C129 cells, 293 cells, Neurospora, and CHO cells, COS cells, HeLa cells, and immortalized mammalian myeloid and lymphoid cell lines. Preferred replication systems include M13, ColE1, SV40, baculovirus, lambda, adenovirus, and the like. A large number of transcription initiation and termination regulatory regions have been isolated and shown to be effective in the transcription and translation of heterologous proteins in the various hosts. Examples of these regions, methods of isolation, manner of manipulation, etc. are known in the art. Under appropriate expression conditions, host cells can be used as a source of recombinantly produced P. aeruginosa-derived peptides and polypeptides.

Advantageously, vectors may also include a transcription regulatory element (i.e., a promoter) operably linked to the P. aeruginosa portion. The promoter may optionally contain operator portions and/or ribosome binding sites. Non-limiting examples of bacterial promoters compatible with E. coli include: b-lactamase (penicillinase) promoter; lactose promoter; tryptophan (trp) promoter; araBAD (arabinose) operon promoter; lambda-derived P₁ promoter and N gene ribosome binding site; and the hybrid tac promoter derived from sequences of the trp and lac UV5 promoters. Non-limiting examples of yeast promoters include 3-phosphoglycerate kinase promoter, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) promoter, galactokinase (GAL1) promoter, galactoepimerase promoter, and alcohol dehydrogenase (ADH) promoter. Suitable promoters for mammalian cells include without limitation viral promoters such as that from Simian Virus 40 (SV40), Rous sarcoma virus (RSV), adenovirus (ADV), and bovine papilloma virus (BPV). Mammalian cells may also require terminator sequences, polyA addition sequences and enhancer sequences to increase expression. Sequences which cause amplification of the gene may also be desirable. Furthermore, sequences that facilitate secretion of the recombinant product from cells, including, but not limited to, bacteria, yeast, and animal cells, such as secretory signal sequences and/or prohormone pro region sequences, may also be included. These sequences are well described in the art.

Nucleic acids encoding wild-type or variant P. aeruginosa-derived polypeptides may also be introduced into cells by recombination events. For example, such a sequence can be introduced into a cell, and thereby effect homologous recombination at the site of an endogenous gene or a sequence with substantial identity to the gene. Other recombination-based methods such as nonhomologous recombinations or deletion of endogenous genes by homologous recombination may also be used.

The nucleic acids of the present invention find use as templates for the recombinant production of P. aeruginosa-derived peptides or polypeptides.

Identification and Use of P. aeruginosa Nucleic Acid Sequences

The disclosed P. aeruginosa polypeptide and nucleic acid sequences, or other sequences that are contained within ORFs, including complete protein-coding sequences, of which any of the disclosed P. aeruginosa-specific sequences forms a part, are useful as target components for diagnosis and/or treatment of P. aeruginosa-caused infection

It will be understood that the sequence of an entire protein-coding sequence of which each disclosed nucleic acid sequence forms a part can be isolated and identified based on each disclosed sequence. This can be achieved, for example, by using an isolated nucleic acid encoding the disclosed sequence, or fragments thereof, to prime a sequencing reaction with genomic P. aeruginosa DNA as template; this is followed by sequencing the amplified product. The isolated nucleic acid encoding the disclosed sequence, or fragments thereof, can also be hybridized to P. aeruginosa genomic libraries to identify clones containing additional complete segments of the protein-coding sequence of which the shorter sequence forms a part. Then, the entire protein-coding sequence, or fragments thereof, or nucleic acids encoding all or part of the sequence, or sequence-conservative or function-conservative variants thereof, may be employed in practicing the present invention.

Preferred sequences are those that are useful in diagnostic and/or therapeutic applications. Diagnostic applications include without limitation nucleic-acid-based and antibody-based methods for detecting bacterial infection. Therapeutic applications include without limitation vaccines, passive immunotherapy, and drug treatments directed against gene products that are both unique to bacteria and essential for growth and/or replication of bacteria.

Identification of Nucleic Acids Encoding Vaccine Components and Targets for Agents Effective Against P. aeruginosa

The disclosed P. aeruginosa genome sequence includes segments that direct the synthesis of ribonucleic acids and polypeptides, as well as origins of replication, promoters, other types of regulatory sequences, and intergenic nucleic acids. The invention encompasses nucleic acids encoding immunogenic components of vaccines and targets for agents effective against P. aeruginosa. Identification of said immunogenic components involved in the determination of the function of the disclosed sequences, which can be achieved using a variety of approaches. Non-limiting examples of these approaches are described briefly below.

Homology to known sequences:

Computer-assisted comparison of the disclosed P. aeruginosa sequences with previously reported sequences present in publicly available databases is useful for identifying functional P. aeruginosa nucleic acid and polypeptide sequences. It will be understood that protein-coding sequences, for example, may be compared as a whole, and that a high degree of sequence homology between two proteins (such as, for example, >80-90%) at the amino acid level indicates that the two proteins also possess some degree of functional homology, such as, for example, among enzymes involved in metabolism, DNA synthesis, or cell wall synthesis, and proteins involved in transport, cell division, etc. In addition, many structural features of particular protein classes have been identified and correlate with specific consensus sequences, such as, for example, binding domains for nucleotides, DNA, metal ions, and other small molecules; sites for covalent modifications such as phosphorylation, acylation, and the like; sites of protein:protein interactions, etc. These consensus sequences may be quite short and thus may represent only a fraction of the entire protein-coding sequence. Identification of such a feature in a P. aeruginosa sequence is therefore useful in determining the function of the encoded protein and identifying useful targets of antibacterial drugs.

Of particular relevance to the present invention are structural features that are common to secretory, transmembrane, and surface proteins, including secretion signal peptides and hydrophobic transmembrane domains. P. aeruginosa proteins identified as containing putative signal sequences and/or transmembrane domains are useful as immunogenic components of vaccines.

Targets for therapeutic drugs according to the invention include, but are not limited to, polypeptides of the invention, whether unique to P. aeruginosa or not, that are essential for growth and/or viability of P. aeruginosa under at least one growth condition. Polypeptides essential for growth and/or viability can be determined by examining the effect of deleting and/or disrupting the genes, i.e., by so-called gene “knockout”. Alternatively, genetic footprinting can be used (Smith et al., 1995, Proc. Natl. Acad. Sci. USA 92:5479-6433; Published International Application WO 94/26933; U.S. Pat. No. 5,612,180). Still other methods for assessing essentiality includes the ability to isolate conditional lethal mutations in the specific gene (e.g., temperature sensitive mutations). Other useful targets for therapeutic drugs, which include polypeptides that are not essential for growth or viability per se but lead to loss of viability of the cell, can be used to target therapeutic agents to cells.

Strain-specific sequences:

Because of the evolutionary relationship between different P. aeruginosa strains, it is believed that the presently disclosed P. aeruginosa sequences are useful for identifying, and/or discriminating between, previously known and new P. aeruginosa strains. It is believed that other P. aeruginosa strains will exhibit at least about 70% sequence homology with the presently disclosed sequence. Systematic and routine analyses of DNA sequences derived from samples containing P. aeruginosa strains, and comparison with the present sequence allows for the identification of sequences that can be used to discriminate between strains, as well as those that are common to all P. aeruginosa strains. In one embodiment, the invention provides nucleic acids, including probes, and peptide and polypeptide sequences that discriminate between different strains of P. aeruginosa. Strain-specific components can also be identified functionally by their ability to elicit or react with antibodies that selectively recognize one or more P. aeruginosa strains.

In another embodiment, the invention provides nucleic acids, including probes, and peptide and polypeptide sequences that are common to all P. aeruginosa strains but are not found in other bacterial species.

P. aeruginosa Polypeptides

This invention encompasses isolated P. aeruginosa polypeptides encoded by the disclosed P. aeruginosa genomic sequences, including the polypeptides of the invention contained in the Sequence Listing. Polypeptides of the invention are preferably at least about 5 amino acid residues in length. Using the DNA sequence information provided herein, the amino acid sequences of the polypeptides encompassed by the invention can be deduced using methods well-known in the art. It will be understood that the sequence of an entire nucleic acid encoding a P. aeruginosa polypeptide can be isolated and identified based on an ORF that encodes only a fragment of the cognate protein-coding region. This can be achieved, for example, by using the isolated nucleic acid encoding the ORF, or fragments thereof, to prime a polymerase chain reaction with genomic P. aeruginosa DNA as template; this is followed by sequencing the amplified product.

The polypeptides of the present invention, including function-conservative variants of the disclosed ORFs, may be isolated from wild-type or mutant P. aeruginosa cells, or from heterologous organisms or cells (including, but not limited to, bacteria, fungi, insect, plant, and mammalian cells) including P. aeruginosa into which a P. aeruginosa-derived protein-coding sequence has been introduced and expressed. Furthermore, the polypeptides may be part of recombinant fusion proteins.

P. aeruginosa polypeptides of the invention can be chemically synthesized using commercially automated procedures such as those referenced herein, including, without limitation, exclusive solid phase synthesis, partial solid phase methods, fragment condensation or classical solution synthesis. The polypeptides are preferably prepared by solid phase peptide synthesis as described by Merrifield, 1963, J. Am. Chem. Soc. 85:2149. The synthesis is carried out with amino acids that are protected at the alpha-amino terminus. Trifunctional amino acids with labile side-chains are also protected with suitable groups to prevent undesired chemical reactions from occurring during the assembly of the polypeptides. The alpha-amino protecting group is selectively removed to allow subsequent reaction to take place at the amino-terminus. The conditions for the removal of the alpha-amino protecting group do not remove the side-chain protecting groups.

Methods for polypeptide purification are well-known in the art, including, without limitation, preparative disc-gel electrophoresis, isoelectric focusing, HPLC, reversed-phase HPLC, gel filtration, ion exchange and partition chromatography, and countercurrent distribution. For some purposes, it is preferable to produce the polypeptide in a recombinant system in which the P. aeruginosa protein contains an additional sequence tag that facilitates purification, such as, but not limited to, a polyhistidine sequence. The polypeptide can then be purified from a crude lysate of the host cell by chromatography on an appropriate solid-phase matrix. Alternatively, antibodies produced against a P. aeruginosa protein or against peptides derived therefrom can be used as purification reagents. Other purification methods are possible.

The present invention also encompasses derivatives and homologues of P. aeruginosa-encoded polypeptides. For some purposes, nucleic acid sequences encoding the peptides may be altered by substitutions, additions, or deletions that provide for functionally equivalent molecules, i.e., function-conservative variants. For example, one or more amino acid residues within the sequence can be substituted by another amino acid of similar properties, such as, for example, positively charged amino acids (arginine, lysine, and histidine); negatively charged amino acids (aspartate and glutamate); polar neutral amino acids; and non-polar amino acids.

The isolated polypeptides may be modified by, for example, phosphorylation, sulfation, acylation, or other protein modifications. They may also be modified with a label capable of providing a detectable signal, either directly or indirectly, including, but not limited to, radioisotopes and fluorescent compounds.

To identify P. aeruginosa-derived polypeptides for use in the present invention, essentially the complete genomic sequence of a virulent, methicillin-resistant isolate of Pseudomonas aeruginosa isolate was analyzed. While, in very rare instances, a nucleic acid sequencing error may be revealed, resolving a rare sequencing error is well within the art, and such an occurrence will not prevent one skilled in the art from practicing the invention.

Also encompassed are any P. aeruginosa polypeptide sequences that are contained within the open reading frames (ORFs), including complete protein-coding sequences, of which any of SEQ ID NO: 1-SEQ ID NO: 16571 forms a part. Table 2, which is appended herewith and which forms part of the present specification, provides a putative identification of the particular function of a polypeptide which is encoded by each ORF, based on the homology match (determined by the BLAST algorithm) of the predicted polypeptide with known proteins encoded by ORFs in other organisms. As a result, one skilled in the art can use the polypeptides of the present invention for commercial and industrial purposes consistent with the type of putative identification of the polypeptide.

The present invention provides a library of P. aeruginosa-derived polypeptide sequences, and a corresponding library of nucleic acid sequences encoding the polypeptides, wherein the polypeptides themselves, or polypeptides contained within ORFs of which they form a part, comprise sequences that are contemplated for use as components of vaccines. Non-limiting examples of such sequences are listed by SEQ ID NO in Table 2, which is appended herewith and which forms part of the present specification.

The present invention also provides a library of P. aeruginosa-derived polypeptide sequences, and a corresponding library of nucleic acid sequences encoding the polypeptides, wherein the polypeptides themselves, or polypeptides contained within ORFs of which they form a part, comprise sequences lacking homology to any known prokaryotic or eukaryotic sequences. Such libraries provide probes, primers, and markers which can be used to diagnose P. aeruginosa infection, including use as markers in epidemiological studies. Non-limiting examples of such sequences are listed by SEQ ID NO in Table 2, which is appended hereto and a part hereof.

The present invention also provides a library of P. aeruginosa-derived polypeptide sequences, and a corresponding library of nucleic acid sequences encoding the polypeptides, wherein the polypeptides themselves, or polypeptides contained within ORFs of which they form a part, comprise targets for therapeutic drugs.

SPECIFIC EXAMPLE Determination of Pseudomonas Protein Antigens for Antibody and Vaccine Development

The selection of Pseudomonas protein antigens for vaccine development can be derived from the nucleic acids encoding P. aeruginosa polypeptides. First, the ORF's can be analyzed for homology to other known exported or membrane proteins and analyzed using the discriminant analysis described by Klein, et al. (Klein, P., Kanehsia, M., and DeLisi, C. (1985) Biochimica et Biophysica Acta 815, 468-476) for predicting exported and membrane proteins.

Homology searches can be performed using the BLAST algorithm contained in the Wisconsin Sequence Analysis Package (Genetics Computer Group, University Research Park, 575 Science Drive, Madison, Wis. 53711) to compare each predicted ORF amino acid sequence with all sequences found in the current GenBank, SWISS-PROT and PIR databases. BLAST searches for local alignments between the ORF and the databank sequences and reports a probability score which indicates the probability of finding this sequence by chance in the database. ORF's with significant homology (e.g. probabilities lower than 1×10⁻⁶ that the homology is only due to random chance) to membrane or exported proteins represent protein antigens for vaccine development. Possible functions can be provided to P. aeruginosa genes based on sequence homology to genes cloned in other organisms.

Discriminant analysis (Klein, et al. supra) can be used to examine the ORF amino acid sequences. This algorithm uses the intrinsic information contained in the ORF amino acid sequence and compares it to information derived from the properties of known membrane and exported proteins. This comparison predicts which proteins will be exported, membrane associated or cytoplasmic. ORF amino acid sequences identified as exported or membrane associated by this algorithm are likely protein antigens for vaccine development.

Production of Fragments and Analogs of P. aeruginosa Nucleic Acids and Polypeptides

Based on the discovery of the P. aeruginosa gene products of the invention provided in the Sequence Listing, one skilled in the art can alter the disclosed structure of P. aeruginosa genes, e.g., by producing fragments or analogs, and test the newly produced structures for activity. Examples of techniques known to those skilled in the relevant art which allow the production and testing of fragments and analogs are discussed below. These, or analogous methods can be used to make and screen libraries of polypeptides, e.g., libraries of random peptides or libraries of fragments or analogs of cellular proteins for the ability to bind P. aeruginosa polypeptides. Such screens are useful for the identification of inhibitors of P. aeruginosa.

Generation of Fragments

Fragments of a protein can be produced in several ways, e.g., recombinantly, by proteolytic digestion, or by chemical synthesis. Internal or terminal fragments of a polypeptide can be generated by removing one or more nucleotides from one end (for a terminal fragment) or both ends (for an internal fragment) of a nucleic acid which encodes the polypeptide. Expression of the mutagenized DNA produces polypeptide fragments. Digestion with “end-nibbling” endonucleases can thus generate DNAs which encode an array of fragments. DNAs which encode fragments of a protein can also be generated by random shearing, restriction digestion or a combination of the above-discussed methods.

Fragments can also be chemically synthesized using techniques known in the art such as conventional Merrifield solid phase f-Moc or t-Boc chemistry. For example, peptides of the present invention may be arbitrarily divided into fragments of desired length with no overlap of the fragments, or divided into overlapping fragments of a desired length.

Alteration of Nucleic Acids and Polypeptides: Random Methods

Amino acid sequence variants of a protein can be prepared by random mutagenesis of DNA which encodes a protein or a particular domain or region of a protein. Useful methods include PCR mutagenesis and saturation mutagenesis. A library of random amino acid sequence variants can also be generated by the synthesis of a set of degenerate oligonucleotide sequences. (Methods for screening proteins in a library of variants are elsewhere herein).

PCR Mutagenesis

In PCR mutagenesis, reduced Taq polymerase fidelity is used to introduce random mutations into a cloned fragment of DNA (Leung et al., 1989, Technique 1:11-15). The DNA region to be mutagenized is amplified using the polymerase chain reaction (PCR) under conditions that reduce the fidelity of DNA synthesis by Taq DNA polymerase, e.g., by using a dGTP/dATP ratio of five and adding Mn²⁺ to the PCR reaction. The pool of amplified DNA fragments are inserted into appropriate cloning vectors to provide random mutant libraries.

Saturation Mutagenesis

Saturation mutagenesis allows for the rapid introduction of a large number of single base substitutions into cloned DNA fragments (Mayers et al., 1985, Science 229:242). This technique includes generation of mutations, e.g., by chemical treatment or irradiation of single-stranded DNA in vitro, and synthesis of a complimentary DNA strand. The mutation frequency can be modulated by modulating the severity of the treatment, and essentially all possible base substitutions can be obtained. Because this procedure does not involve a genetic selection for mutant fragments both neutral substitutions, as well as those that alter function, are obtained. The distribution of point mutations is not biased toward conserved sequence elements.

Degenerate Oligonucleotides

A library of homologs can also be generated from a set of degenerate oligonucleotide sequences. Chemical synthesis of a degenerate sequences can be carried out in an automatic DNA synthesizer, and the synthetic genes then ligated into an appropriate expression vector. The synthesis of degenerate oligonucleotides is known in the art (see for example, Narang, S A (1983) Tetrahedron 39:3; Itakura et al. (1981) Recombinant DNA, Proc 3rd Cleveland Sympos. Macromolecules, ed. A G Walton, Amsterdam: Elsevier pp273-289; Itakura et al. (1984) Annu. Rev. Biochem. 53:323; Itakura et al. (1984) Science 198:1056; Ike et al. (1983) Nucleic Acid Res. 11:477. Such techniques have been employed in the directed evolution of other proteins (see, for example, Scott et al. (1990) Science 249:386-390; Roberts et al. (1992) PNAS 89:2429-2433; Devlin et al. (1990) Science 249: 404-406; Cwirla et al. (1990) PNAS 87: 6378-6382; as well as U.S. Pat. Nos. 5,223,409, 5,198,346, and 5,096,815).

Alteration of Nucleic Acids and Polypeptides: Methods for Directed Mutagenesis

Non-random or directed, mutagenesis techniques can be used to provide specific sequences or mutations in specific regions. These techniques can be used to create variants which include, e.g., deletions, insertions, or substitutions, of residues of the known amino acid sequence of a protein. The sites for mutation can be modified individually or in series, e.g., by (1) substituting first with conserved amino acids and then with more radical choices depending upon results achieved, (2) deleting the target residue, or (3) inserting residues of the same or a different class adjacent to the located site, or combinations of options 1-3.

Alanine Scanning Mutagenesis

Alanine scanning mutagenesis is a useful method for identification of certain residues or regions of the desired protein that are preferred locations or domains for mutagenesis, Cunningham and Wells (Science 244:1081-1085, 1989). In alanine scanning, a residue or group of target residues are identified (e.g., charged residues such as Arg, Asp, His, Lys, and Glu) and replaced by a neutral or negatively charged amino acid (most preferably alanine or polyalanine). Replacement of an amino acid can affect the interaction of the amino acids with the surrounding aqueous environment in or outside the cell. Those domains demonstrating functional sensitivity to the substitutions are then refined by introducing further or other variants at or for the sites of substitution. Thus, while the site for introducing an amino acid sequence variation is predetermined, the nature of the mutation per se need not be predetermined. For example, to optimize the performance of a mutation at a given site, alanine scanning or random mutagenesis may be conducted at the target codon or region and the expressed desired protein subunit variants are screened for the optimal combination of desired activity.

Oligonucleotide-Mediated Mutagenesis

Oligonucleotide-mediated mutagenesis is a useful method for preparing substitution, deletion, and insertion variants of DNA, see, e.g., Adelman et al., (DNA 2:183, 1983). Briefly, the desired DNA is altered by hybridizing an oligonucleotide encoding a mutation to a DNA template, where the template is the single-stranded form of a plasmid or bacteriophage containing the unaltered or native DNA sequence of the desired protein. After hybridization, a DNA polymerase is used to synthesize an entire second complementary strand of the template that will thus incorporate the oligonucleotide primer, and will code for the selected alteration in the desired protein DNA. Generally, oligonucleotides of at least about 25 nucleotides in length are used. An optimal oligonucleotide will have 12 to 15 nucleotides that are completely complementary to the template on either side of the nucleotide(s) coding for the mutation. This ensures that the oligonucleotide will hybridize properly to the single-stranded DNA template molecule. The oligonucleotides are readily synthesized using techniques known in the art such as that described by Crea et al. (Proc. Natl. Acad. Sci. USA, 75: 5765 [1978]).

Cassette Mutagenesis

Another method for preparing variants, cassette mutagenesis, is based on the technique described by Wells et al. (Gene, 34:315 [1985]). The starting material is a plasmid (or other vector) which includes the protein subunit DNA to be mutated. The codon(s) in the protein subunit DNA to be mutated are identified. There must be a unique restriction endonuclease site on each side of the identified mutation site(s). If no such restriction sites exist, they may be generated using the above-described oligonucleotide-mediated mutagenesis method to introduce them at appropriate locations in the desired protein subunit DNA. After the restriction sites have been introduced into the plasmid, the plasmid is cut at these sites to linearize it. A double-stranded oligonucleotide encoding the sequence of the DNA between the restriction sites but containing the desired mutation(s) is synthesized using standard procedures. The two strands are synthesized separately and then hybridized together using standard techniques. This double-stranded oligonucleotide is referred to as the cassette. This cassette is designed to have 3′ and 5′ ends that are comparable with the ends of the linearized plasmid, such that it can be directly ligated to the plasmid. This plasmid now contains the mutated desired protein subunit DNA sequence.

Combinatorial Mutagenesis

Combinatorial mutagenesis can also be used to generate mutants (Ladner et al., WO 88/06630). In this method, the amino acid sequences for a group of homologs or other related proteins are aligned, preferably to promote the highest homology possible. All of the amino acids which appear at a given position of the aligned sequences can be selected to create a degenerate set of combinatorial sequences. The variegated library of variants is generated by combinatorial mutagenesis at the nucleic acid level, and is encoded by a variegated gene library. For example, a mixture of synthetic oligonucleotides can be enzymatically ligated into gene sequences such that the degenerate set of potential sequences are expressible as individual peptides, or alternatively, as a set of larger fusion proteins containing the set of degenerate sequences.

Other Modifications of P. aeruginosa Nucleic Acids and Polypeptides

It is possible to modify the structure of a P. aeruginosa polypeptide for such purposes as increasing solubility, enhancing stability (e.g., shelf life ex vivo and resistance to proteolytic degradation in vivo). A modified P. aeruginosa protein or peptide can be produced in which the amino acid sequence has been altered, such as by amino acid substitution, deletion, or addition as described herein.

An P. aeruginosa peptide can also be modified by substitution of cysteine residues preferably with alanine, serine, threonine, leucine or glutamic acid residues to minimize dimerization via disulfide linkages. In addition, amino acid side chains of fragments of the protein of the invention can be chemically modified. Another modification is cyclization of the peptide.

In order to enhance stability and/or reactivity, a P. aeruginosa polypeptide can be modified to incorporate one or more polymorphisms in the amino acid sequence of the protein resulting from any natural allelic variation. Additionally, D-amino acids, non-natural amino acids, or non-amino acid analogs can be substituted or added to produce a modified protein within the scope of this invention. Furthermore, an P. aeruginosa polypeptide can be modified using polyethylene glycol (PEG) according to the method of A. Sehon and co-workers (Wie et al., supra) to produce a protein conjugated with PEG. In addition, PEG can be added during chemical synthesis of the protein. Other modifications of P. aeruginosa proteins include reduction/alkylation (Tarr, Methods of Protein Microcharacterization, J. E. Silver ed., Humana Press, Clifton N.J. 155-194 (1986)); acylation (Tarr, supra); chemical coupling to an appropriate carrier (Mishell and Shiigi, eds, Selected Methods in Cellular Immunology, W H Freeman, San Francisco, Calif. (1980), U.S. Pat. No. 4,939,239; or mild formalin treatment (Marsh, (1971) Int. Arch. of Allergy and Appl. Immunol., 41: 199-215).

To facilitate purification and potentially increase solubility of a P. aeruginosa protein or peptide, it is possible to add an amino acid fusion moiety to the peptide backbone. For example, hexa-histidine can be added to the protein for purification by immobilized metal ion affinity chromatography (Hochuli, E. et al., (1988) Bio/Technology, 6: 1321-1325). In addition, to facilitate isolation of peptides free of irrelevant sequences, specific endoprotease cleavage sites can be introduced between the sequences of the fusion moiety and the peptide.

To potentially aid proper antigen processing of epitopes within an P. aeruginosa polypeptide, canonical protease sensitive sites can be engineered between regions, each comprising at least one epitope via recombinant or synthetic methods. For example, charged amino acid pairs, such as KK or RR, can be introduced between regions within a protein or fragment during recombinant construction thereof. The resulting peptide can be rendered sensitive to cleavage by cathepsin and/or other trypsin-like enzymes which would generate portions of the protein containing one or more epitopes. In addition, such charged amino acid residues can result in an increase in the solubility of the peptide.

Primary Methods for Screening Polypeptides and Analogs

Various techniques are known in the art for screening generated mutant gene products. Techniques for screening large gene libraries often include cloning the gene library into replicable expression vectors, transforming appropriate cells with the resulting library of vectors, and expressing the genes under conditions in which detection of a desired activity, e.g., in this case, binding to P. aeruginosa polypeptide or an interacting protein, facilitates relatively easy isolation of the vector encoding the gene whose product was detected. Each of the techniques described below is amenable to high through-put analysis for screening large numbers of sequences created, e.g., by random mutagenesis techniques.

Two Hybrid Systems

Two hybrid assays such as the system described below (as with the other screening methods described herein), can be used to identify polypeptides, e.g., fragments or analogs of a naturally-occurring P. aeruginosa polypeptide, e.g., of cellular proteins, or of randomly generated polypeptides which bind to an P. aeruginosa protein. (The P. aeruginosa domain is used as the bait protein and the library of variants are expressed as prey fusion proteins.) In an analogous fashion, a two hybrid assay (as with the other screening methods described herein), can be used to find polypeptides which bind a P. aeruginosa polypeptide.

Display Libraries

In one approach to screening assays, the Pseudomonas peptides are displayed on the surface of a cell or viral particle, and the ability of particular cells or viral particles to bind an appropriate receptor protein via the displayed product is detected in a “panning assay”. For example, the gene library can be cloned into the gene for a surface membrane protein of a bacterial cell, and the resulting fusion protein detected by panning (Ladner et al., WO 88/06630; Fuchs et al. (1991) Bio/Technology 9:1370-1371; and Goward et al. (1992) TIBS 18:136-140). In a similar fashion, a detectably labeled ligand can be used to score for potentially functional peptide homologs. Fluorescently labeled ligands, e.g., receptors, can be used to detect homologs which retain ligand-binding activity. The use of fluorescently labeled ligands, allows cells to be visually inspected and separated under a fluorescence microscope, or, where the morphology of the cell permits, to be separated by a fluorescence-activated cell sorter.

A gene library can be expressed as a fusion protein on the surface of a viral particle. For instance, in the filamentous phage system, foreign peptide sequences can be expressed on the surface of infectious phage, thereby conferring two significant benefits. First, since these phage can be applied to affinity matrices at concentrations well over 10¹³ phage per milliliter, a large number of phage can be screened at one time. Second, since each infectious phage displays a gene product on its surface, if a particular phage is recovered from an affinity matrix in low yield, the phage can be amplified by another round of infection. The group of almost identical E. coli filamentous phages, M13, fd., and f1, are most often used in phage display libraries. Either of the phage gIII or gVIII coat proteins can be used to generate fusion proteins without disrupting the ultimate packaging of the viral particle. Foreign epitopes can be expressed at the NH₂-terminal end of pIII and phage bearing such epitopes recovered from a large excess of phage lacking this epitope (Ladner et al. PCT publication WO 90/02909; Garrard et al., PCT publication WO 92/09690; Marks et al. (1992) J. Biol. Chem. 267:16007-16010; Griffiths et al. (1993) EMBO J 12:725-734; Clackson et al. (1991) Nature 352:624-628; and Barbas et al. (1992) PNAS 89:4457-4461).

A common approach uses the maltose receptor of E. coli (the outer membrane protein, LamB) as a peptide fusion partner (Charbit et al. (1986) EMBO 5, 3029-3037). Oligonucleotides have been inserted into plasmids encoding the LamB gene to produce peptides fused into one of the extracellular loops of the protein. These peptides are available for binding to ligands, e.g., to antibodies, and can elicit an immune response when the cells are administered to animals. Other cell surface proteins, e.g., OmpA (Schorr et al. (1991) Vaccines 91, pp. 387-392), PhoE (Agterberg, et al. (1990) Gene 88, 37-45), and PAL (Fuchs et al. (1991) Bio/Tech 9, 1369-1372), as well as large bacterial surface structures have served as vehicles for peptide display. Peptides can be fused to pilin, a protein which polymerizes to form the pilus-a conduit for interbacterial exchange of genetic information (Thiry et al. (1989) Appl. Environ. Microbiol. 55, 984-993). Because of its role in interacting with other cells, the pilus provides a useful support for the presentation of peptides to the extracellular environment. Another large surface structure used for peptide display is the bacterial motive organ, the flagellum. Fusion of peptides to the subunit protein flagellin offers a dense array of many peptide copies on the host cells (Kuwajima et al. (1988) Bio/Tech. 6, 1080-1083). Surface proteins of other bacterial species have also served as peptide fusion partners. Examples include the Staphylococcus protein A and the outer membrane IgA protease of Neisseria (Hansson et al. (1992) J. Bacteriol. 174, 4239-4245 and Klauser et al. (1990) EMBO J. 9, 1991-1999).

In the filamentous phage systems and the LamB system described above, the physical link between the peptide and its encoding DNA occurs by the containment of the DNA within a particle (cell or phage) that carries the peptide on its surface. Capturing the peptide captures the particle and the DNA within. An alternative scheme uses the DNA-binding protein LacI to form a link between peptide and DNA (Cull et al. (1992) PNAS USA 89:1865-1869). This system uses a plasmid containing the LacI gene with an oligonucleotide cloning site at its 3′-end. Under the controlled induction by arabinose, a LacI-peptide fusion protein is produced. This fusion retains the natural ability of LacI to bind to a short DNA sequence known as LacO operator (LacO). By installing two copies of LacO on the expression plasmid, the LacI-peptide fusion binds tightly to the plasmid that encoded it. Because the plasmids in each cell contain only a single oligonucleotide sequence and each cell expresses only a single peptide sequence, the peptides become specifically and stablely associated with the DNA sequence that directed its synthesis. The cells of the library are gently lysed and the peptide-DNA complexes are exposed to a matrix of immobilized receptor to recover the complexes containing active peptides. The associated plasmid DNA is then reintroduced into cells for amplification and DNA sequencing to determine the identity of the peptide ligands. As a demonstration of the practical utility of the method, a large random library of dodecapeptides was made and selected on a monoclonal antibody raised against the opioid peptide dynorphin B. A cohort of peptides was recovered, all related by a consensus sequence corresponding to a six-residue portion of dynorphin B. (Cull et al. (1992) Proc. Natl. Acad. Sci. U.S.A. 89-1869)

This scheme, sometimes referred to as peptides-on-plasmids, differs in two important ways from the phage display methods. First, the peptides are attached to the C-terminus of the fusion protein, resulting in the display of the library members as peptides having free carboxy termini. Both of the filamentous phage coat proteins, pIII and pVIII, are anchored to the phage through their C-termini, and the guest peptides are placed into the outward-extending N-terminal domains. In some designs, the phage-displayed peptides are presented right at the amino terminus of the fusion protein. (Cwirla, et al. (1990) Proc. Natl. Acad. Sci. U.S.A 87, 6378-6382) A second difference is the set of biological biases affecting the population of peptides actually present in the libraries. The LacI fusion molecules are confined to the cytoplasm of the host cells. The phage coat fusions are exposed briefly to the cytoplasm during translation but are rapidly secreted through the inner membrane into the periplasmic compartment, remaining anchored in the membrane by their C-terminal hydrophobic domains, with the N-termini, containing the peptides, protruding into the periplasm while awaiting assembly into phage particles. The peptides in the LacI and phage libraries may differ significantly as a result of their exposure to different proteolytic activities. The phage coat proteins require transport across the inner membrane and signal peptidase processing as a prelude to incorporation into phage. Certain peptides exert a deleterious effect on these processes and are underrepresented in the libraries (Gallop et al. (1994) J. Med. Chem. 37(9):1233-1251). These particular biases are not a factor in the LacI display system.

The number of small peptides available in recombinant random libraries is enormous. Libraries of 10⁷-10⁹ independent clones are routinely prepared. Libraries as large as 10¹¹ recombinants have been created, but this size approaches the practical limit for clone libraries. This limitation in library size occurs at the step of transforming the DNA containing randomized segments into the host bacterial cells. To circumvent this limitation, an in vitro system based on the display of nascent peptides in polysome complexes has recently been developed. This display library method has the potential of producing libraries 3-6 orders of magnitude larger than the currently available phage/phagemid or plasmid libraries. Furthermore, the construction of the libraries, expression of the peptides, and screening, is done in an entirely cell-free format.

In one application of this method (Gallop et al. (1994) J. Med. Chem. 37(9):1233-1251), a molecular DNA library encoding 10¹² decapeptides was constructed and the library expressed in an E. coli S30 in vitro coupled transcription/translation system. Conditions were chosen to stall the ribosomes on the mRNA, causing the accumulation of a substantial proportion of the RNA in polysomes and yielding complexes containing nascent peptides still linked to their encoding RNA. The polysomes are sufficiently robust to be affinity purified on immobilized receptors in much the same way as the more conventional recombinant peptide display libraries are screened. RNA from the bound complexes is recovered, converted to cDNA, and amplified by PCR to produce a template for the next round of synthesis and screening. The polysome display method can be coupled to the phage display system. Following several rounds of screening, cDNA from the enriched pool of polysomes was cloned into a phagemid vector. This vector serves as both a peptide expression vector, displaying peptides fused to the coat proteins, and as a DNA sequencing vector for peptide identification. By expressing the polysome-derived peptides on phage, one can either continue the affinity selection procedure in this format or assay the peptides on individual clones for binding activity in a phage ELISA, or for binding specificity in a completion phage ELISA (Barret, et al. (1992) Anal. Biochem 204,357-364). To identify the sequences of the active peptides one sequences the DNA produced by the phagemid host.

Secondary Screening of Polypeptides and Analogs

The high through-put assays described above can be followed by secondary screens in order to identify further biological activities which will, e.g., allow one skilled in the art to differentiate agonists from antagonists. The type of a secondary screen used will depend on the desired activity that needs to be tested. For example, an assay can be developed in which the ability to inhibit an interaction between a protein of interest and its respective ligand can be used to identify antagonists from a group of peptide fragments isolated though one of the primary screens described above.

Therefore, methods for generating fragments and analogs and testing them for activity are known in the art. Once the core sequence of interest is identified, it is routine for one skilled in the art to obtain analogs and fragments.

Peptide Mimetics of P. aeruginosa Polypeptides

The invention also provides for reduction of the protein binding domains of the subject P. aeruginosa polypeptides to generate mimetics, e.g. peptide or non-peptide agents. The peptide mimetics are able to disrupt binding of a polypeptide to its counter ligand, e.g., in the case of a P. aeruginosa polypeptide binding to a naturally occurring ligand. The critical residues of a subject P. aeruginosa polypeptide which are involved in molecular recognition of a polypeptide can be determined and used to generate P. aeruginosa-derived peptidomimetics which competitively or noncompetitively inhibit binding of the P. aeruginosa polypeptide with an interacting polypeptide (see, for example, European patent applications EP-412,762A and EP-B31,080A).

For example, scanning mutagenesis can be used to map the amino acid residues of a particular P. aeruginosa polypeptide involved in binding an interacting polypeptide, peptidomimetic compounds (e.g. diazepine or isoquinoline derivatives) can be generated which mimic those residues in binding to an interacting polypeptide, and which therefore can inhibit binding of a P. aeruginosa polypeptide to an interacting polypeptide and thereby interfere with the function of P. aeruginosa polypeptide. For instance, non-hydrolyzable peptide analogs of such residues can be generated using benzodiazepine (e.g., see Freidinger et al. in Peptides: Chemistry and Biology, G. R. Marshall ed., ESCOM Publisher: Leiden, Netherlands, 1988), azepine (e.g., see Huffman et al. in Peptides: Chemistry and Biology, G. R. Marshall ed., ESCOM Publisher: Leiden, Netherlands, 1988), substituted gama lactam rings (Garvey et al. in Peptides: Chemistry and Biology, G. R. Marshall ed., ESCOM Publisher: Leiden, Netherlands, 1988), keto-methylene pseudopeptides (Ewenson et al. (1986) J Med Chem 29:295; and Ewenson et al. in Peptides: Structure and Function (Proceedings of the 9th American Peptide Symposium) Pierce Chemical Co. Rockland, Ill., 1985), b-turn dipeptide cores (Nagai et al. (1985) Tetrahedron Lett 26:647; and Sato et al. (1986) J Chem Soc Perkin Trans 1:1231), and b-aminoalcohols (Gordon et al. (1985) Biochem Biophys Res Commun 126:419; and et al. (1986) Biochem Biophys Res Commun 134:71).

Vaccine Formulations for P. aeruginosa Nucleic Acids and Polypeptides

This invention also features vaccine compositions for protection against infection by P. aeruginosa or for treatment of P. aeruginosa infection. In one embodiment, the vaccine compositions contain one or more immunogenic components such as a surface protein from P. aeruginosa, or portion thereof, and a pharmaceutically acceptable carrier. Nucleic acids within the scope of the invention are exemplified by the nucleic acids of the invention contained in the Sequence Listing which encode P. aeruginosa surface proteins. Any nucleic acid encoding an immunogenic P. aeruginosa protein, or portion thereof, which is capable of expression in a cell, can be used in the present invention. These vaccines have therapeutic and prophylactic utilities.

One aspect of the invention provides a vaccine composition for protection against infection by P. aeruginosa which contains at least one immunogenic fragment of an P. aeruginosa protein and a pharmaceutically acceptable carrier. Preferred fragments include peptides of at least about 10 amino acid residues in length, preferably about 10-20 amino acid residues in length, and more preferably about 12-16 amino acid residues in length.

Immunogenic components of the invention can be obtained, for example, by screening polypeptides recombinantly produced from the corresponding fragment of the nucleic acid encoding the full-length P. aeruginosa protein. In addition, fragments can be chemically synthesized using techniques known in the art such as conventional Merrifield solid phase f-Moc or t-Boc chemistry.

In one embodiment, immunogenic components are identified by the ability of the peptide to stimulate T cells. Peptides which stimulate T cells, as determined by, for example, T cell proliferation or cytokine secretion are defined herein as comprising at least one T cell epitope. T cell epitopes are believed to be involved in initiation and perpetuation of the immune response to the protein allergen which is responsible for the clinical symptoms of allergy. These T cell epitopes are thought to trigger early events at the level of the T helper cell by binding to an appropriate HLA molecule on the surface of an antigen presenting cell, thereby stimulating the T cell subpopulation with the relevant T cell receptor for the epitope. These events lead to T cell proliferation, lymphokine secretion, local inflammatory reactions, recruitment of additional immune cells to the site of antigen/T cell interaction, and activation of the B cell cascade, leading to the production of antibodies. A T cell epitope is the basic element, or smallest unit of recognition by a T cell receptor, where the epitope comprises amino acids essential to receptor recognition (e.g., approximately 6 or 7 amino acid residues). Amino acid sequences which mimic those of the T cell epitopes are within the scope of this invention.

Screening immunogenic components can be accomplished using one or more of several different assays. For example, in vitro, peptide T cell stimulatory activity is assayed by contacting a peptide known or suspected of being immunogenic with an antigen presenting cell which presents appropriate MHC molecules in a T cell culture. Presentation of an immunogenic P. aeruginosa peptide in association with appropriate MHC molecules to T cells in conjunction with the necessary co-stimulation has the effect of transmitting a signal to the T cell that induces the production of increased levels of cytokines, particularly of interleukin-2 and interleukin-4. The culture supernatant can be obtained and assayed for interleukin-2 or other known cytokines. For example, any one of several conventional assays for interleukin-2 can be employed, such as the assay described in Proc. Natl. Acad. Sci USA, 86: 1333 (1989) the pertinent portions of which are incorporated herein by reference. A kit for an assay for the production of interferon is also available from Genzyme Corporation (Cambridge, Mass.).

Alternatively, a common assay for T cell proliferation entails measuring tritiated thymidine incorporation. The proliferation of T cells can be measured in vitro by determining the amount of ³H-labeled thymidine incorporated into the replicating DNA of cultured cells. Therefore, the rate of DNA synthesis and, in turn, the rate of cell division can be quantified.

Vaccine compositions of the invention containing immunogenic components (e.g., P. aeruginosa polypeptide or fragment thereof or nucleic acid encoding an P. aeruginosa polypeptide or fragment thereof) preferably include a pharmaceutically acceptable carrier. The term “pharmaceutically acceptable carrier” refers to a carrier that does not cause an allergic reaction or other untoward effect in patients to whom it is administered. Suitable pharmaceutically acceptable carriers include, for example, one or more of water, saline, phosphate buffered saline, dextrose, glycerol, ethanol and the like, as well as combinations thereof. Pharmaceutically acceptable carriers may further comprise minor amounts of auxiliary substances such as wetting or emulsifying agents, preservatives or buffers, which enhance the shelf life or effectiveness of the antibody. For vaccines of the invention containing P. aeruginosa polypeptides, the polypeptide is co-administered with a suitable adjuvant.

It will be apparent to those of skill in the art that the therapeutically effective amount of DNA or protein of this invention will depend, inter alia, upon the administration schedule, the unit dose of antibody administered, whether the protein or DNA is administered in combination with other therapeutic agents, the immune status and health of the patient, and the therapeutic activity of the particular protein or DNA.

Vaccine compositions are conventionally administered parenterally, e.g., by injection, either subcutaneously or intramuscularly. Methods for intramuscular immunization are described by Wolff et al. (1990) Science 247: 1465-1468 and by Sedegah et al. (1994) Immunology 91: 9866-9870. Other modes of administration include oral and pulmonary formulations, suppositories, and transdermal applications. Oral immunization is preferred over parenteral methods for inducing protection against infection by P. aeruginosa. Cain et. al. (1993) Vaccine 11: 637-642. Oral formulations include such normally employed excipients as, for example, pharmaceutical grades of mannitol, lactose, starch, magnesium stearate, sodium saccharine, cellulose, magnesium carbonate, and the like.

The vaccine compositions of the invention can include an adjuvant, including, but not limited to aluminum hydroxide; N-acetyl-muramyl--L-threonyl-D-isoglutamine (thr-MDP); N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine (CGP 11637, referred to as nor-MDP); N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanine-2-(1′-2′-dipalmitoyl-sn-glycero-3-hydroxyphos-phoryloxy)-ethylamine (CGP 19835A, referred to a MTP-PE); RIBI, which contains three components from bacteria; monophosphoryl lipid A; trehalose dimycoloate; cell wall skeleton (MPL+TDM+CWS) in a 2% squalene/Tween 80 emulsion; and cholera toxin. Others which may be used are non-toxic derivatives of cholera toxin, including its B subunit, and/or conjugates or genetically engineered fusions of the P. aeruginosa polypeptide with cholera toxin or its B subunit, procholeragenoid, fungal polysaccharides, including schizophyllan, muramyl dipeptide, muramyl dipeptide derivatives, phorbol esters, labile toxin of E. coli, non-P. aeruginosa bacterial lysates, block polymers or saponins.

Other suitable delivery methods include biodegradable microcapsules or immuno-stimulating complexes (ISCOMs), cochleates, or liposomes, genetically engineered attenuated live vectors such as viruses or bacteria, and recombinant (chimeric) virus-like particles, e.g., bluetongue. The amount of adjuvant employed will depend on the type of adjuvant used. For example, when the mucosal adjuvant is cholera toxin, it is suitably used in an amount of 5 mg to 50 mg, for example 10 mg to 35 mg. When used in the form of microcapsules, the amount used will depend on the amount employed in the matrix of the microcapsule to achieve the desired dosage. The determination of this amount is within the skill of a person of ordinary skill in the art.

Carrier systems in humans may include enteric release capsules protecting the antigen from the acidic environment of the stomach, and including P. aeruginosa polypeptide in an insoluble form as fusion proteins. Suitable carriers for the vaccines of the invention are enteric coated capsules and polylactide-glycolide microspheres. Suitable diluents are 0.2 N NaHCO₃ and/or saline.

Vaccines of the invention can be administered as a primary prophylactic agent in adults or in children, as a secondary prevention, after successful eradication of P. aeruginosa in an infected host, or as a therapeutic agent in the aim to induce an immune response in a susceptible host to prevent infection by P. aeruginosa. The vaccines of the invention are administered in amounts readily determined by persons of ordinary skill in the art. Thus, for adults a suitable dosage will be in the range of 10 mg to 10 g, preferably 10 mg to 100 mg. A suitable dosage for adults will also be in the range of 5 mg to 500 mg. Similar dosage ranges will be applicable for children. Those skilled in the art will recognize that the optimal dose may be more or less depending upon the patient's body weight, disease, the route of administration, and other factors. Those skilled in the art will also recognize that appropriate dosage levels can be obtained based on results with known oral vaccines such as, for example, a vaccine based on an E. coli lysate (6 mg dose daily up to total of 540 mg) and with an enterotoxigenic E. coli purified antigen (4 doses of 1 mg) (Schulman et al., J. Urol. 150:917-921 (1993); Boedecker et al., American Gastroenterological Assoc. 999:A-222 (1993)). The number of doses will depend upon the disease, the formulation, and efficacy data from clinical trials. Without intending any limitation as to the course of treatment, the treatment can be administered over 3 to 8 doses for a primary immunization schedule over 1 month (Boedeker, American Gastroenterological Assoc. 888:A-222 (1993)).

In a preferred embodiment, a vaccine composition of the invention can be based on a killed whole E. coli preparation with an immunogenic fragment of a P. aeruginosa protein of the invention expressed on its surface or it can be based on an E. coli lysate, wherein the killed E. coli acts as a carrier or an adjuvant.

It will be apparent to those skilled in the art that some of the vaccine compositions of the invention are useful only for preventing P. aeruginosa infection, some are useful only for treating P. aeruginosa infection, and some are useful for both preventing and treating P. aeruginosa infection. In a preferred embodiment, the vaccine composition of the invention provides protection against P. aeruginosa infection by stimulating humoral and/or cell-mediated immunity against P. aeruginosa. It should be understood that amelioration of any of the symptoms of P. aeruginosa infection is a desirable clinical goal, including a lessening of the dosage of medication used to treat P. aeruginosa-caused disease, or an increase in the production of antibodies in the serum or mucous of patients.

Antibodies Reactive with P. aeruginosa Polypeptides

The invention also includes antibodies specifically reactive with the subject P. aeruginosa polypeptide. Anti-protein/anti-peptide antisera or monoclonal antibodies can be made by standard protocols (See, for example, Antibodies: A Laboratory Manual ed. by Harlow and Lane (Cold Spring Harbor Press: 1988)). A mammal such as a mouse, a hamster or rabbit can be immunized with an immunogenic form of the peptide. Techniques for conferring immunogenicity on a protein or peptide include conjugation to carriers or other techniques well known in the art. An immunogenic portion of the subject P. aeruginosa polypeptide can be administered in the presence of adjuvant. The progress of immunization can be monitored by detection of antibody titers in plasma or serum. Standard ELISA or other immunoassays can be used with the immunogen as antigen to assess the levels of antibodies.

In a preferred embodiment, the subject antibodies are immunospecific for antigenic determinants of the P. aeruginosa polypeptides of the invention, e.g. antigenic determinants of a polypeptide of the invention contained in the Sequence Listing, or a closely related human or non-human mammalian homolog (e.g., about 90% homologous, more preferably at least about 95% homologous). In yet a further preferred embodiment of the invention, the anti-P. aeruginosa antibodies do not substantially cross react (i.e., react specifically) with a protein which is for example, less than 80% percent homologous to a sequence of the invention contained in the Sequence Listing. By “not substantially cross react”, it is meant that the antibody has a binding affinity for a non-homologous protein which is less than 10 percent, more preferably less than 5 percent, and even more preferably less than 1 percent, of the binding affinity for a protein of the invention contained in the Sequence Listing. In a most preferred embodiment, there is no cross-reactivity between bacterial and mammalian antigens.

The term antibody as used herein is intended to include fragments thereof which are also specifically reactive with P. aeruginosa polypeptides. Antibodies can be fragmented using conventional techniques and the fragments screened for utility in the same manner as described above for whole antibodies. For example, F(ab′)₂ fragments can be generated by treating antibody with pepsin. The resulting F(ab′)₂ fragment can be treated to reduce disulfide bridges to produce Fab′ fragments. The antibody of the invention is further intended to include bispecific and chimeric molecules having an anti-P. aeruginosa portion.

Both monoclonal and polyclonal antibodies (Ab) directed against P. aeruginosa polypeptides or P. aeruginosa polypeptide variants, and antibody fragments such as Fab′ and F(ab′)₂, can be used to block the action of P. aeruginosa polypeptide and allow the study of the role of a particular P. aeruginosa polypeptide of the invention in aberrant or unwanted intracellular signaling, as well as the normal cellular function of the P. aeruginosa and by microinjection of anti-P. aeruginosa polypeptide antibodies of the present invention.

Antibodies which specifically bind P. aeruginosa epitopes can also be used in immunohistochemical staining of tissue samples in order to evaluate the abundance and pattern of expression of P. aeruginosa antigens. Anti-P. aeruginosa polypeptide antibodies can be used diagnostically in immuno-precipitation and immuno-blotting to detect and evaluate P. aeruginosa levels in tissue or bodily fluid as part of a clinical testing procedure. Likewise, the ability to monitor P. aeruginosa polypeptide levels in an individual can allow determination of the efficacy of a given treatment regimen for an individual afflicted with such a disorder. The level of a P. aeruginosa polypeptide can be measured in cells found in bodily fluid, such as in urine samples or can be measured in tissue, such as produced by gastric biopsy. Diagnostic assays using anti-P. aeruginosa antibodies can include, for example, immunoassays designed to aid in early diagnosis of P. aeruginosa infections. The present invention can also be used as a method of detecting antibodies contained in samples from individuals infected by this bacterium using specific P. aeruginosa antigens.

Another application of anti-P. aeruginosa polypeptide antibodies of the invention is in the immunological screening of cDNA libraries constructed in expression vectors such as λgt11, λgt18-23, λZAP, and λORF8. Messenger libraries of this type, having coding sequences inserted in the correct reading frame and orientation, can produce fusion proteins. For instance, λgt11 will produce fusion proteins whose amino termini consist of β-galactosidase amino acid sequences and whose carboxy termini consist of a foreign polypeptide. Antigenic epitopes of a subject P. aeruginosa polypeptide can then be detected with antibodies, as, for example, reacting nitrocellulose filters lifted from infected plates with anti-P. aeruginosa polypeptide antibodies. Phage, scored by this assay, can then be isolated from the infected plate. Thus, the presence of P. aeruginosa gene homologs can be detected and cloned from other species, and alternate isoforms (including splicing variants) can be detected and cloned.

Kits Containing Nucleic Acids, Polypeptides or Antibodies of the Invention

The nucleic acid, polypeptides and antibodies of the invention can be combined with other reagents and articles to form kits. Kits for diagnostic purposes typically comprise the nucleic acid, polypeptides or antibodies in vials or other suitable vessels. Kits typically comprise other reagents for performing hybridization reactions, polymerase chain reactions (PCR), or for reconstitution of lyophilized components, such as aqueous media, salts, buffers, and the like. Kits may also comprise reagents for sample processing such as detergents, chaotropic salts and the like. Kits may also comprise immobilization means such as particles, supports, wells, dipsticks and the like. Kits may also comprise labeling means such as dyes, developing reagents, radioisotopes, fluorescent agents, luminescent or chemiluminescent agents, enzymes, intercalating agents and the like. With the nucleic acid and amino acid sequence information provided herein, individuals skilled in art can readily assemble kits to serve their particular purpose. Kits further can include instructions for use.

Bio Chip Technology

The nucleic acid sequence of the present invention may be used to detect P. aeruginosa or other species of Pseudomonas acid sequence using bio chip technology. Bio chips containing arrays of nucleic acid sequence can also be used to measure expression of genes of P. aeruginosa or other species of Pseudomonas. For example, to diagnose a patient with a P. aeruginosa or other Pseudomonas infection, a sample from a human or animal can be used as a probe on a bio chip containing an array of nucleic acid sequence from the present invention. In addition, a sample from a disease state can be compared to a sample from a non-disease state which would help identify a gene that is up-regulated or expressed in the disease state. This would provide valuable insight as to the mechanism by which the disease manifests. Changes in gene expression can also be used to identify critical pathways involved in drug transport or metabolism, and may enable the identification of novel targets involved in virulence or host cell interactions involved in maintenance of an infection. Procedures using such techniques have been described by Brown et al., 1995, Science 270: 467-470.

Bio chips can also be used to monitor the genetic changes of potential therapeutic compounds including, deletions, insertions or mismatches. Once the therapeutic is added to the patient, changes to the genetic sequence can be evaluated for its efficacy. In addition, the nucleic acid sequence of the present invention can be used to determine essential genes in cell cycling. As described in Iyer et al., 1999 (Science, 283:83-87) genes essential in the cell cycle can be identified using bio chips. Furthermore, the present invention provides nucleic acid sequences which can be used with bio chip technology to understand regulatory networks in bacteria, measure the response to environmental signals or drugs as in drug screening, and study virulence induction. (Mons et al., 1998, Nature Biotechnology, 16: 45-48. Patents teaching this technology include U.S. Pat. Nos. 5,445,934, 5,744,305, and 5,800,992.

Drug Screening Assays Using P. aeruginosa Polypeptides

By making available purified and recombinant P. aeruginosa polypeptides, the present invention provides assays which can be used to screen for drugs which are either agonists or antagonists of the normal cellular function, in this case, of the subject P. aeruginosa polypeptides, or of their role in intracellular signaling. Such inhibitors or potentiators may be useful as new therapeutic agents to combat P. aeruginosa infections in humans. A variety of assay formats will suffice and, in light of the present inventions, will be comprehended by the person skilled in the art.

In many drug screening programs which test libraries of compounds and natural extracts, high throughput assays are desirable in order to maximize the number of compounds surveyed in a given period of time. Assays which are performed in cell-free systems, such as may be derived with purified or semi-purified proteins, are often preferred as “primary” screens in that they can be generated to permit rapid development and relatively easy detection of an alteration in a molecular target which is mediated by a test compound. Moreover, the effects of cellular toxicity and/or bioavailability of the test compound can be generally ignored in the in vitro system, the assay instead being focused primarily on the effect of the drug on the molecular target as may be manifest in an alteration of binding affinity with other proteins or change in enzymatic properties of the molecular target. Accordingly, in an exemplary screening assay of the present invention, the compound of interest is contacted with an isolated and purified P. aeruginosa polypeptide.

Screening assays can be constructed in vitro with a purified P. aeruginosa polypeptide or fragment thereof, such as a P. aeruginosa polypeptide having enzymatic activity, such that the activity of the polypeptide produces a detectable reaction product. The efficacy of the compound can be assessed by generating dose response curves from data obtained using various concentrations of the test compound. Moreover, a control assay can also be performed to provide a baseline for comparison. Suitable products include those with distinctive absorption, fluorescence, or chemiluminescence properties, for example, because detection may be easily automated. A variety of synthetic or naturally occurring compounds can be tested in the assay to identify those which inhibit or potentiate the activity of the P. aeruginosa polypeptide. Some of these active compounds may directly, or with chemical alterations to promote membrane permeability or solubility, also inhibit or potentiate the same activity (e.g., enzymatic activity) in whole, live P. aeruginosa cells.

Overexpression Assays

Overexpression assays are based on the premise that overproduction of a protein would lead to a higher level of resistance to compounds that selectively interfere with the function of that protein. Overexpression assays may be used to identify compounds that interfere with the function of virtually any type of protein, including without limitation enzymes, receptors, DNA- or RNA-binding proteins, or any proteins that are directly or indirectly involved in regulating cell growth.

Typically, two bacterial strains are constructed. One contains a single copy of the gene of interest, and a second contains several copies of the same gene. Identification of useful inhibitory compounds of this type of assay is based on a comparison of the activity of a test compound in inhibiting growth and/or viability of the two strains. The method involves constructing a nucleic acid vector that directs high level expression of a particular target nucleic acid. The vectors are then transformed into host cells in single or multiple copies to produce strains that express low to moderate and high levels of protein encoding by the target sequence (strain A and B, respectively). Nucleic acid comprising sequences encoding the target gene can, of course, be directly integrated into the host cell.

Large numbers of compounds (or crude substances which may contain active compounds) are screened for their effect on the growth of the two strains. Agents which interfere with an unrelated target equally inhibit the growth of both strains. Agents which interfere with the function of the target at high concentration should inhibit the growth of both strains. It should be possible, however, to titrate out the inhibitory effect of the compound in the overexpressing strain. That is, if the compound is affecting the particular target that is being tested, it should be possible to inhibit the growth of strain A at a concentration of the compound that allows strain B to grow.

Alternatively, a bacterial strain is constructed that contains the gene of interest under the control of an inducible promoter. Identification of useful inhibitory agents using this type of assay is based on a comparison of the activity of a test compound in inhibiting growth and/or viability of this strain under both inducing and non-inducing conditions. The method involves constructing a nucleic acid vector that directs high-level expression of a particular target nucleic acid. The vector is then transformed into host cells that are grown under both non-inducing and inducing conditions (conditions A and B, respectively).

Large numbers of compounds (or crude substances which may contain active compounds) are screened for their effect on growth under these two conditions. Agents that interfere with the function of the target should inhibit growth under both conditions. It should be possible, however, to titrate out the inhibitory effect of the compound in the overexpressing strain. That is, if the compound is affecting the particular target that is being tested, it should be possible to inhibit growth under condition A at a concentration that allows the strain to grow under condition B.

Ligand-binding Assays

Many of the targets according to the invention have functions that have not yet been identified. Ligand-binding assays are useful to identify inhibitor compounds that interfere with the function of a particular target, even when that function is unknown. These assays are designed to detect binding of test compounds to particular targets. The detection may involve direct measurement of binding. Alternatively, indirect indications of binding may involve stabilization of protein structure or disruption of a biological function. Non-limiting examples of useful ligand-binding assays are detailed below.

A useful method for the detection and isolation of binding proteins is the Biomolecular Interaction Assay (BIAcore) system developed by Pharmacia Biosensor and described in the manufacturer's protocol (LKB Pharmacia, Sweden). The BIAcore system uses an affinity purified anti-GST antibody to immobilize GST-fusion proteins onto a sensor chip. The sensor utilizes surface plasmon resonance which is an optical phenomenon that detects changes in refractive indices. In accordance with the practice of the invention, a protein of interest is coated onto a chip and test compounds are passed over the chip. Binding is detected by a change in the refractive index (surface plasmon resonance).

A different type of ligand-binding assay involves scintillation proximity assays (SPA, described in U.S. Pat. No. 4,568,649).

Another type of ligand binding assay, also undergoing development, is based on the fact that proteins containing mitochondrial targeting signals are imported into isolated mitochondria in vitro (Hurt et al., 1985, Embo J. 4:2061-2068; Eilers and Schatz, Nature, 1986, 322:228-231). In a mitochondrial import assay, expression vectors are constructed in which nucleic acids encoding particular target proteins are inserted downstream of sequences encoding mitochondrial import signals. The chimeric proteins are synthesized and tested for their ability to be imported into isolated mitochondria in the absence and presence of test compounds. A test compound that binds to the target protein should inhibit its uptake into isolated mitochondria in vitro.

Another ligand-binding assay is the yeast two-hybrid system (Fields and Song, 1989, Nature 340:245-246). The yeast two-hybrid system takes advantage of the properties of the GAL4 protein of the yeast Saccharomyces cerevisiae. The GAL4 protein is a transcriptional activator required for the expression of genes encoding enzymes of galactose utilization. This protein consists of two separable and functionally essential domains: an N-terminal domain which binds to specific DNA sequences (UAS_(G)); and a C-terminal domain containing acidic regions, which is necessary to activate transcription. The native GAL4 protein, containing both domains, is a potent activator of transcription when yeast are grown on galactose media. The N-terminal domain binds to DNA in a sequence-specific manner but is unable to activate transcription. The C-terminal domain contains the activating regions but cannot activate transcription because it fails to be localized to UAS_(G). In the two-hybrid system, a system of two hybrid proteins containing parts of GAL4: (1) a GAL4 DNA-binding domain fused to a protein ‘X’ and (2) a GAL4 activation region fused to a protein ‘Y’. If X and Y can form a protein—protein complex and reconstitute proximity of the GAL4 domains, transcription of a gene regulated by UAS_(G) occurs. Creation of two hybrid proteins, each containing one of the interacting proteins X and Y, allows the activation region of UAS_(G) to be brought to its normal site of action.

The binding assay described in Fodor et al., 1991, Science 251:767-773, which involves testing the binding affinity of test compounds for a plurality of defined polymers synthesized on a solid substrate, may also be useful.

Compounds which bind to the polypeptides of the invention are potentially useful as antibacterial agents for use in therapeutic compositions.

Pharmaceutical formulations suitable for antibacterial therapy comprise the antibacterial agent in conjunction with one or more biologically acceptable carriers. Suitable biologically acceptable carriers include, but are not limited to, phosphate-buffered saline, saline, deionized water, or the like. Preferred biologically acceptable carriers are physiologically or pharmaceutically acceptable carriers.

The antibacterial compositions include an antibacterial effective amount of active agent. Antibacterial effective amounts are those quantities of the antibacterial agents of the present invention that afford prophylactic protection against bacterial infections or which result in amelioration or cure of an existing bacterial infection. This antibacterial effective amount will depend upon the agent, the location and nature of the infection, and the particular host. The amount can be determined by experimentation known in the art, such as by establishing a matrix of dosages and frequencies and comparing a group of experimental units or subjects to each point in the matrix.

The antibacterial active agents or compositions can be formed into dosage unit forms, such as for example, creams, ointments, lotions, powders, liquids, tablets, capsules, suppositories, sprays, aerosols or the like. If the antibacterial composition is formulated into a dosage unit form, the dosage unit form may contain an antibacterial effective amount of active agent. Alternatively, the dosage unit form may include less than such an amount if multiple dosage unit forms or multiple dosages are to be used to administer a total dosage of the active agent. Dosage unit forms can include, in addition, one or more excipient(s), diluent(s), disintegrant(s), lubricant(s), plasticizer(s), colorant(s), dosage vehicle(s), absorption enhancer(s), stabilizer(s), bactericide(s), or the like.

For general information concerning formulations, see, e.g., Gilman et al. (eds.), 1990, Goodman and Gilman's: The Pharmacological Basis of Therapeutics, 8th ed., Pergamon Press; and Remington's Pharmaceutical Sciences, 17th ed., 1990, Mack Publishing Co., Easton, Pa.; Avis et al. (eds.), 1993, Pharmaceutical Dosage Forms: Parenteral Medications, Dekker, New York; Lieberman et al (eds.), 1990, Pharmaceutical Dosage Forms: Disperse Systems, Dekker, New York.

The antibacterial agents and compositions of the present invention are useful for preventing or treating P. aeruginosa infections. Infection prevention methods incorporate a prophylactically effective amount of an antibacterial agent or composition. A prophylactically effective amount is an amount effective to prevent P. aeruginosa infection and will depend upon the specific bacterial strain, the agent, and the host. These amounts can be determined experimentally by methods known in the art and as described above.

P. aeruginosa infection treatment methods incorporate a therapeutically effective amount of an antibacterial agent or composition. A therapeutically effective amount is an amount sufficient to ameliorate or eliminate the infection. The prophylactically and/or therapeutically effective amounts can be administered in one administration or over repeated administrations. Therapeutic administration can be followed by prophylactic administration, once the initial bacterial infection has been resolved.

The antibacterial agents and compositions can be administered topically or systemically. Topical application is typically achieved by administration of creams, ointments, lotions, or sprays as described above. Systemic administration includes both oral and parental routes. Parental routes include, without limitation, subcutaneous, intramuscular, intraperitoneal, intravenous, transdermal, inhalation and intranasal administration.

EXEMPLIFICATION Cloning and Sequencing P. aeruginosa Genomic Sequence

This invention provides nucleotide sequences of the genome of P. aeruginosa which thus comprises a DNA sequence library of P. aeruginosa genomic DNA. The detailed description that follows provides nucleotide sequences of P. aeruginosa, and also describes how the sequences were obtained and how ORFs (Open Reading Frames) and protein-coding sequences can be identified. Also described are methods of using the disclosed P. aeruginosa sequences in methods including diagnostic and therapeutic applications. Furthermore, the library can be used as a database for identification and comparison of medically important sequences in this and other strains of P. aeruginosa as well as other species of Pseudomonas.

Chromosomal DNA from strain 19804 of P. aeruginosa was isolated after Zymolyase digestion, sodium dodecyl sulfate lysis, potassium acetate precipitation, phenol:chloroform extraction and ethanol precipitation (Soll, D. R., T. Srikantha and S. R. Lockhart: Characterizing Developmentally Regulated Genes in P. aeruginosa. In Microbial Genome Methods. K. W. Adolph, editor. CRC Press. New York. p 17-37.). Genomic P. aeruginosa DNA was hydrodynamically sheared in an HPLC and then separated on a standard 1% agarose gel. Fractions corresponding to 2500-3000 bp in length were excised from the gel and purifed by the GeneClean procedure (Bio101, Inc.).

The purified DNA fragments were then blunt-ended using T4 DNA polymerase. The healed DNA was then ligated to unique BstXI-linker adapters (5′-GTCTTCACCACGGGG-3′ and 5′-GTGGTGAAGAC-3′ in 100-1000 fold molar excess). These linkers are complimentary to the BstXI-cut pGTC vector, while the overhang is not self-complimentary. Therefore, the linkers will not concatermerize nor will the cut-vector religate itself easily. The linker-adapted inserts were separated from the unincorporated linkers on a 1% agarose gel and purified using GeneClean. The linker-adapted inserts were then ligated to BstXI-cut vector to construct a “shotgun” sublclone libraries.

Only major modifications to the protocols are highlighted. Briefly, the library was then transformed into DH5á competent cells (Gibco/BRL, DH5á transformation protocol). It was assessed by plating onto antibiotic plates containing ampicillin and IPTG/Xgal. The plates were incubated overnight at 37° C. Transformants were then used for plating of clones and picking for sequencing. The cultures were grown overnight at 37° C. DNA was purified using a silica bead DNA preparation (Engelstein, 1996) method. In this manner, 25 μg of DNA was obtained per clone.

These purified DNA samples were then sequenced using primarily ABI dye-terminator chemistry. All subsequent steps were based on sequencing by ABI377 automated DNA sequencing methods. The ABI dye terminator sequence reads were run on ABI377 machines and the data was transferred to UNIX machines following lane tracking of the gels. Base calls and quality scores were determined using the program PHRED (Ewing et al., 1998, Genome Res. 8: 175-185; Ewing and Green, 1998, Genome Res. 8: 685-734). Reads were assembled using PHRAP (P. Green, Abstracts of DOE Human Genome Program Contractor-Grantee Workshop V, January 1996, p.157) with default program parameters and quality scores. The initial assembly was done at 6-fold coverage and yielded 162 contigs.

Finishing can follow the initial assembly. Missing mates (sequences from clones that only gave reads from one end of the Pseudomonas DNA inserted in the plasmid) can be identified and sequenced with ABI technology to allow the identification of additional overlapping contigs.

End-sequencing of randomly picked genomic lambda was also performed. Sequencing on a both sides was done for all lambda sequences. The lambda library backbone helped to verify the integrity of the assembly and allowed closure of some of the physical gaps.Primers for walking off the ends of contigs would be selected using pick_primer (a GTC program) near the ends of the clones to facilitate gap closure. These walks can be sequenced using the selected clones and primers. These data are then reassembled with PHRAP. Additional sequencing using PCR-generated templates and screened and/or unscreened lambda templates can be done in addition.

To identify P. aeruginosa polypeptides the complete genomic sequence of P. aeruginosa were analyzed essentially as follows: First, all possible stop-to-stop open reading frames (ORFs) greater than 180 nucleotides in all six reading frames were translated into amino acid sequences. Second, the identified ORFs were analyzed for homology to known (archeabacter, prokaryotic and eukaryotic) protein sequences. Third, the coding potential of non-homologous sequences were evaluated with the program GENEMARKTM (Borodovsky and McIninch, 1993, Comp. Chem. 17:123).

Identification, Cloning and Expression of P. aeruginosa Nucleic Acids

Expression and purification of the P. aeruginosa polypeptides of the invention can be performed essentially as outlined below.

To facilitate the cloning, expression and purification of membrane and secreted proteins from P. aeruginosa, a gene expression system, such as the pET System (Novagen), for cloning and expression of recombinant proteins in E. coli, is selected. Also, a DNA sequence encoding a peptide tag, the His-Tag, is fused to the 3′ end of DNA sequences of interest in order to facilitate purification of the recombinant protein products. The 3′ end is selected for fusion in order to avoid alteration of any 5′ terminal signal sequence.

PCR Amplification and Cloning of Nucleic Acids Containing ORF's Encoding Enzymes

Nucleic acids chosen (for example, from the nucleic acids set forth in SEQ ID NO: 1-SEQ ID NO:16571) for cloning from the 19804 strain of P. aeruginosa are prepared for amplification cloning by polymerase chain reaction (PCR). Synthetic oligonucleotide primers specific for the 5′ and 3′ ends of open reading frames (ORFs) are designed and purchased from GibcoBRL Life Technologies (Gaithersburg, Md., USA). All forward primers (specific for the 5′ end of the sequence) are designed to include an NcoI cloning site at the extreme 5′ terminus. These primers are designed to permit initiation of protein translation at a methionine residue followed by a valine residue and the coding sequence for the remainder of the native P. aeruginosa DNA sequence. All reverse primers (specific for the 3′ end of any P. aeruginosa ORF) include a EcoRI site at the extreme 5′ terminus to permit cloning of each P. aeruginosa sequence into the reading frame of the pET-28b. The pET-28b vector provides sequence encoding an additional 20 carboxy-terminal amino acids including six histidine residues (at the extreme C-terminus), which comprise the His-Tag.

Genomic DNA prepared from the 19804 strain of P. aeruginosa is used as the source of template DNA for PCR amplification reactions (Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994). To amplify a DNA sequence containing a P. aeruginosa ORF, genomic DNA (50 nanograms) is introduced into a reaction vial containing 2 mM MgCl₂, 1 micromolar synthetic oligonucleotide primers (forward and reverse primers) complementary to and flanking a defined P. aeruginosa ORF, 0.2 mM of each deoxynucleotide triphosphate; dATP, dGTP, dCTP, dTTP and 2.5 units of heat stable DNA polymerase (Amplitaq, Roche Molecular Systems, Inc., Branchburg, N.J., USA) in a final volume of 100 microliters.

Upon completion of thermal cycling reactions, each sample of amplified DNA is washed and purified using the Qiaquick Spin PCR purification kit (Qiagen, Gaithersburg, Md., USA). All amplified DNA samples are subjected to digestion with the restriction endonucleases, e.g., NcoI and EcoRI (New England BioLabs, Beverly, Mass., USA)(Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994). DNA samples are then subjected to electrophoresis on 1.0% NuSeive (FMC BioProducts, Rockland, Me. USA) agarose gels. DNA is visualized by exposure to ethidium bromide and long wave uv irradiation. DNA contained in slices isolated from the agarose gel is purified using the Bio 101 GeneClean Kit protocol (Bio 101 Vista, Calif., USA).

Cloning of P. aeruginosa Nucleic Acids into an Expression Vector

The pET-28b vector is prepared for cloning by digestion with restriction endonucleases, e.g., NcoI and EcoRI (Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994). The pET-28a vector, which encodes a His-Tag that can be fused to the 5′ end of an inserted gene, is prepared by digestion with appropriate restriction endonucleases.

Following digestion, DNA inserts are cloned (Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994) into the previously digested pET-28b expression vector. Products of the ligation reaction are then used to transform the BL21 strain of E. coli (Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994) as described below.

Transformation of Competent Bacteria with Recombinant Plasmids

Competent bacteria, E. coli strain BL21 or E. coli strain BL21(DE3), are transformed with recombinant pET expression plasmids carrying the cloned P. aeruginosa sequences according to standard methods (Current Protocols in Molecular, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994). Briefly, 1 microliter of ligation reaction is mixed with 50 microliters of electrocompetent cells and subjected to a high voltage pulse, after which, samples are incubated in 0.45 milliliters SOC medium (0.5% yeast extract, 2.0% tryptone, 10 mM NaCl, 2.5 mM KCl, 10 mM MgCl2, 10 mM MgSO4 and 20, mM glucose) at 37° C. with shaking for 1 hour. Samples are then spread on LB agar plates containing 25 microgram/ml kanamycin sulfate for growth overnight. Transformed colonies of BL21 are then picked and analyzed to evaluate cloned inserts as described below.

Identification of Recombinant Expression Vectors with P. aeruginosa Nucleic Acids

Individual BL21 clones transformed with recombinant pET-28b P. aeruginosa ORFs are analyzed by PCR amplification of the cloned inserts using the same forward and reverse primers, specific for each P. aeruginosa sequence, that were used in the original PCR amplification cloning reactions. Successful amplification verifies the integration of the P. aeruginosa sequences in the expression vector (Current Protocols in Molecular Biology, John Wiley and Sons, Inc., F. Ausubel et al., eds., 1994).

Isolation and Preparation of Nucleic Acids from Transformants

Individual clones of recombinant pET-28b vectors carrying properly cloned P. aeruginosa ORFs are picked and incubated in 5 mls of LB broth plus 25 microgram/ml kanamycin sulfate overnight. The following day plasmid DNA is isolated and purified using the Qiagen plasmid purification protocol (Qiagen Inc., Chatsworth, Calif., USA).

Expression of Recombinant P. aeruginosa Sequences in E. coli

The pET vector can be propagated in any E. coli K-12 strain e.g. HMS174, HB101, JM109, DH5, etc. for the purpose of cloning or plasmid preparation. Hosts for expression include E. coli strains containing a chromosomal copy of the gene for T7 RNA polymerase. These hosts are lysogens of bacteriophage DE3, a lambda derivative that carries the lacI gene, the lacUV5 promoter and the gene for T7 RNA polymerase. T7 RNA polymerase is induced by addition of isopropyl-B-D-thiogalactoside (IPTG), and the T7 RNA polymerase transcribes any target plasmid, such as pET-28b, carrying its gene of interest. Strains used include: BL21(DE3) (Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990) Meth. Enzymol. 185, 60-89).

To express recombinant P. aeruginosa sequences, 50 nanograms of plasmid DNA isolated as described above is used to transform competent BL21(DE3) bacteria as described above (provided by Novagen as part of the pET expression system kit). The lacZ gene (beta-galactosidase) is expressed in the pET-System as described for the P. aeruginosa recombinant constructions. Transformed cells are cultured in SOC medium for 1 hour, and the culture is then plated on LB plates containing 25 micrograms/ml kanamycin sulfate. The following day, bacterial colonies are pooled and grown in LB medium containing kanamycin sulfate (25 micrograms/ml) to an optical density at 600 nM of 0.5 to 1.0 O.D. units, at which point, 1 millimolar IPTG was added to the culture for 3 hours to induce gene expression of the P. aeruginosa recombinant DNA constructions.

After induction of gene expression with IPTG, bacteria are pelleted by centrifugation in a Sorvall RC-3B centrifuge at 3500× g for 15 minutes at 4° C. Pellets are resuspended in 50 milliliters of cold 10 mM Tris-HCl, pH 8.0, 0.1 M NaCl and 0.1 mM EDTA (STE buffer). Cells are then centrifuged at 2000× g for 20 min at 4° C. Wet pellets are weighed and frozen at −80° C. until ready for protein purification.

A variety of methodologies known in the art can be utilized to purify the isolated proteins. (Current Protocols in Protein Science, John Wiley and Sons, Inc., J. E. Coligan et al., eds., 1995). For example, the frozen cells may be thawed, resupended in buffer and ruptured by several passages through a small volume microfluidizer (Model M-110S, Microfluidics International Corporation, Newton, Mass.). The resultant homogenate may be centrifuged to yield a clear supernatant (crude extract) and following filtration the crude extract may be fractionated over columns. Fractions may be monitored by absorbance at OD₂₈₀ nm and peak fractions may analyzed by SDS-PAGE.

The concentrations of purified protein preparations may be quantified spectrophotometrically using absorbance coefficients calculated from amino acid content (Perkins, S. J. 1986 Eur. J. Biochem. 157, 169-180). Protein concentrations are also measured by the method of Bradford, M. M. (1976) Anal. Biochem. 72, 248-254, and Lowry, O. H., Rosebrough, N., Farr, A. L. & Randall, R. J. (1951) J. Biol. Chem. 193, pages 265-275, using bovine serum albumin as a standard.

SDS-polyacrylamide gels of various concentrations may be purchased from BioRad (Hercules, Calif., USA), and stained with Coomassie blue. Molecular weight markers may include rabbit skeletal muscle myosin (200 kDa), E. coli (-galactosidase (116 kDa), rabbit muscle phosphorylase B (97.4 kDa), bovine serum albumin (66.2 kDa), ovalbumin (45 kDa), bovine carbonic anhydrase (31 kDa), soybean trypsin inhibitor (21.5 kDa), egg white lysozyme (14.4 kDa) and bovine aprotinin (6.5 kDa).

EQUIVALENTS

Those skilled in the art will recognize, or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments and methods described herein. The specific embodiments described herein are offered by way of example only, and the invention is to limited only by the terms of the appended claims, along with the full scope of equivalents to which such claims are entitled.

TABLE 2 NT AA SEQ SEQ NT AA Orf Name ID ID Length Length Score Exponent Organism Accession Description 10954914_f3_4 1 16572 240 79 11976006_f3_3 2 16573 330 110 253 −21 Cyanobacterium JQ1236 synechocystis 5989443_c1_5 3 16574 246 82 200 −16 Vibrio cholerae AF069055 (de:vibrio cholerae sigma54- dependent transcriptional activator 1(s54act1) gene, partial cds.) (nt:catalytic domain) 15830341_c3_4 4 16575 201 67 5083327_f2_2 5 16576 432 144 121 −7 mice|C57BL/6xCBA/ A38346 (sr:, house mouse) CaJ hybrid 26276456_c1_4 6 16577 510 170 457 −43 Pseudomonas AF055999 (de:pseudomonas aeruginosa hemin aeruginosa uptake locus, hypothctical proteinphuw (phuw), atpase component (phuv), abc-type permease (phuu), periplasmic binding protein (phut), hemin degrading factor (phus),and outer membrane hemin receptor (ph . . . 24786541_c2_5 7 16578 477 159 203 −15 minor jackknife L41834 (sr:ensis minor (clone: 1/6) male clam adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 24488558_c3_6 8 16579 507 169 103 −3 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 31363556_c2_5 9 16580 474 157 122 −7 minor jackknife LA1834 (sr:ensis minor (clone: 1/6) male clam adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 16038336_c3_6 10 16581 462 153 107 −4 Homo sapiens Q08170 (sr:,human) (de:pre-mrna splicing factor srp75) 32150880_c2_3 11 16582 234 77 131 −8 Pseudomonas AF010181 (fn:transfers d-rhamnose in an alpha1-2 aeruginosa linkage) (de:pseudomonas aeruginosa glycosyltransferase wbpx (wbpx) gene, complete cds.) (nt:one of three transferases which function to) 35242666_f1_2 12 16583 414 138 108 −5 Boreogadus saida U43200 (dc:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4552288_f3_4 13 16584 237 78 25909416_f3_5 14 16585 201 66 26660177_c1_6 15 16586 741 246 226 −17 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 34628910_c2_7 16 16587 762 254 106 −3 Saimiriine Q01042 (sr:11,) (de:immediate-early protein) herpesvirus 2 25525216_c1_4 17 16588 405 134 14253951_c2_5 18 16589 483 160 10250000_f1_1 19 16590 636 211 325 −29 Escherichia coli P32695 (de:hypothetical 36.8 kd protein in dinf-qor intergenic region) 36414711_c1_7 20 16591 630 209 169 −11 Trypanosoma cruzi A44937 (c1:kinetoplast-associated protein) 32605438_c2_8 21 16592 723 240 186 −14 minor jackknife L41834 (sr:ensis minor (clone: 1/6) male clam adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, completc cds.) (nt:putative) 16973468_c3_9 22 16593 576 191 148 −9 no gb taxonomy Y15174 (de:human papillomavirus type 76 e6, match e7, e1, e2, e4, 12, and 11 genes.) (nt:putative) 16893767_f2_2 23 16594 717 239 161 −10 Aeromonas U56832 (de:aeromonas hydrophila fk506 hydrophila binding protein (fkpa) gene, complete cds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 12272027_f3_3 24 16595 339 112 153 −11 Aquifex acolicus G70456 36567881_c2_6 25 16596 381 126 112 −7 Klebsiella Contig531A GTC ORF with score 134 to: pneumoniae (ai:7000766992) (or:Pseudomonas aeruginosa) 12911468_c3_8 26 16597 666 221 452 −43 Rhizobium meliloti P13632 (de:c4-dicarboxylate transport (megaplasmid transcriptional regulatory protein pRME41B SYM) dcdt) 42558468_f1_1 27 16598 741 246 546 −51 Pseudomonas S53999 (c1:gramicidin s synthetase i repeat aeruginosa homology:acetate--coa ligase homology:acyl carrier protein homology) 9769817_f2_5 28 16599 336 111 26689416_c1_9 29 16600 378 126 15394580_f2_1 30 16601 297 98 375 −34 Escherichia coli U41560 (sr:escherichia coli strain=k-12) (ec:4.2.1.3) (de:escherichia coli aconitase b (acnb) gene, partial cds.) 21562683_f2_2 31 16602 483 160 789 −78 Escherichia coli P36683 (ec:4.2.1.3) (de:(aconitase 2)) 14932213_c1_4 32 16603 519 172 351 −32 Enterobacter cloacae CONTIG503 GTC ORF with score 351 to: (ai:7000756806) (or:Pseudomonas aeruginosa) 31726378_c3_5 33 16604 369 122 248 −20 Enterobacter cloacae CONTIG503 GTC ORF with scorc 2125 to: (ai:7501776800) (or:Klebsiella pneumoniae) 31677056_c3_6 34 16605 423 140 418 −39 Klebsiella Contig530A GTC ORF with score 457 to: pneumoniae (ai:7000802959) (or:Pseudomonas aeruginosa) 7145416_f3_2 35 16606 216 71 14863202_f1_2 36 16607 414 138 509 −49 Pseudomonas putida P13456 (de:recf protein) 35804706_c3_10 37 16608 393 131 200 −16 Escherichia coli S70160 48828120_f3_3 38 16609 333 110 99 −4 Haemophilus P45112 (ec:3.1.—.—) (de:single-stranded- influenzae dna-specific exonuclease recj,) 25862692_f2_2 39 16610 252 83 178 −12 Escherichia coli Y09439 (de:e. coli uup gene, partial.) 11955217_f3_4 40 16611 345 115 289 −25 Bacillus P42100 (de:hypothetical 39.4 kd protein in subtilis/Bacillus gntr-htpg intergenic region) globigii 3256700_c3_7 41 16612 474 158 233 −20 Enterobacter cloacae CONTIG505 GTC ORF with score 474 to: (ai:7501788553) (or:Klebsiella pneumoniae) 24110217_f1_1 42 16613 291 96 96 −4 Pseudomonas putida D85415 (sr:pseudomonas putida (strain:ucc22) dna) (de:pseudomonas putida gene for conversion of aniline to catechol.) (nt:amino group transfer) 14866531_c1_2 43 16614 183 60 98 −4 Acinetobacter CONTIG221 GTC ORF with score 2023 to: baumannii C (ai:98446) (or:Escherichia coli) (sr:escherichia coli (strain:k12) dna clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #278(33.3-33.7 min.).) (nt:orf_id:o277#10; similar to (swissprot accession) 22004128_fI_1 44 16615 495 164 316 −27 Pseudomonas P48632 (de:ferripyoverdine receptor precursor) aeruginosa 13147877_f2_5 45 16616 225 74 32678902_c3_10 46 16617 516 171 132 −8 Pseudomonas P32977 (de:porin o precursor) aeruginosa 36620643_c1_3 47 16618 222 74 36047181_c1_2 48 16619 288 96 36583431_f1_1 49 16620 750 249 118 −7 longfin squid S56117 (sr:, longfin squid) 17082311_f2_3 50 16621 642 213 163 −11 Caenorhabditis Z77655 (de:caenorhabditis elegans cosmid elegans c56a3, complete sequence.) (nt:weak similarity to human calcium- dependent proctase) 9769449_c1_6 51 16622 957 319 172 −10 Homo sapiens O00268 (sr:, human) (de:(tafii135) (tafii-130) 34167937_c3_9 52 16623 726 242 101 −2 Micrococcus luteus JQ0406 22315763_f1_1 53 16624 261 86 12893777_f1_2 54 16625 792 264 178 −12 mice|C57BL/6xCBA/ A28996 (c1:proline-rich protein) (sr:, CaJ hybrid house mouse) 13017587_f2_5 55 16626 513 170 156 −11 Rattus norvegicus M64793 (sr:rat (sprague-dawley) liver dna) (de:rat salivary proline-rich protein (rp15) gene, complete cds.) 25672037_f3_6 56 16627 1146 382 195 −14 Rattus norvegicus B39066 (c1:proline-rich protein) (sr:, norway rat) 31347694_c1_7 57 16628 1104 367 101 −1 medicinal leech U92813 (sr:medicinal leech) (de:hirudo medicinalis tractin mrna, complete cds.) 7320438_c2_8 58 16629 1002 334 583 −56 Escherichia coli P20966 (ec:2.7.1.69) (de:(ec 2.7.1.69) (eii-fru)) 7128152_f2_2 59 16630 234 77 5339715_c3_5 60 16631 285 95 118 −6 Pseudomonas AF051692 (de:pseudomonas aeruginosa lema aeruginosa (lema) gene, partial cds; and responseregulator (pirr), histidine protein kinase (pirs), and phenolate- type ferrisiderophore receptor (pira) genes, complete cds.) (nt:pirs; transmembrane sensor component 34453318_f2_2 61 16632 204 68 107 −5 Pseudomonas P14756 (ec:3.4.24.26) (de:metalloproteinase)) aeruginosa 26823916_f3_8 62 16633 252 83 11875776_f1_1 63 16634 1509 502 222 −15 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 22910840_f1_3 64 16635 1368 455 108 −5 Klebsiella Contig503A GTC ORF with scorc 129 to: pneumoniae (ai:7000772531) (or:Pseudomonas aeruginosa) 33417277_f1_5 65 16636 3684 1227 135 −6 Klebsiella Contig554A GTC ORF with score 362 to: pneumoniae (ai:7000831455) (or:Entcrobacter cloacae) 31900181_f1_6 66 16637 297 99 132 −8 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 10650693_f3_24 67 16638 570 189 106 −3 Canis familiaris A45195 (c1:guanylate cyclase catalytic domain homology) (sr:, dog) 15804056_f3_26 68 16639 537 178 148 −9 Murine herpesvirus U97553 (de:murine herpesvirus 68 strain 68 wums, complete genome.) 31845968_f3_27 69 16640 288 95 106 −5 Oryctolagus U46069 (sr:european rabbit) (de:oryctolagus cuniculus cuniculus fertilin alpha subunit mrna, complete cds.) (nt:sperm surface protein with metalloproteinase and) 31486567_f3_37 70 16641 480 160 159 −10 equine herpesvirus AF030027 (fn:very large tegument protein) type 4 EHV-4 (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 26844849_c1_38 71 16642 7527 2509 3311 −9999 Pseudomonas S53999 (c1:gramicidin s synthetase i repeat aeruginosa homology:acetate--coa ligase homology:acyl carrier protein homology) 13942533_c2_45 72 16643 501 166 98 −5 Aspergillus Contig8635 GTC ORF with score 98 to: fumigatus (ai:7000756994) (or:Pseudomonas aeruginosa) 13142958_c3_54 73 16644 489 162 96 −2 Plasmodium P08674 (sr:gombak,) (de:circumsporozoite cynomolgi protein precursor (cs)) 32632056_c3_65 74 16645 720 239 150 −8 Acanthamoeba P19706 (sr:, amoeba) (de:myosin heavy chain castellanii ib (myosin heavy chain iI)) 29932330_f1_1 75 16646 465 154 143 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 13806881_f1_2 76 16647 1131 376 177 −11 Molluscum U60315 (de:molluscum contagiosum virus contagiosum virus subtype 1, complete genome.) subtype 1 (nt:putative dna topoisomerase i; description: homolog) 34609680_f1_4 77 16648 201 66 35682205_f1_8 78 16649 1245 414 12007067_f1_9 79 16650 435 144 100 −3 Caenorhabditis AF045646 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid f56b3.) (nt:contains similarity to collagens) 1429168_f2_15 80 16651 663 220 104 −3 Homo sapiens AF022224 (fn:anti-apoptotic protein) (sr:human) (de:homo sapiens bc1-2-binding protein (bag-1) mrna, complete cds.) (nt:bag-11; long form of bag-1; contains nuclear) 22135833_f2_16 81 16652 435 144 111 −5 Saccharomyces P08640 (sr:, baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 16069832_f2_17 82 16653 435 144 101 −3 equine herpesvirus D88734 (sr:equine herpesvirus 1 type 1 EVH-1 (strain:bk343, isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 35828876_f2_21 83 16654 1449 482 1635 −168 Pseudomonas putida M57613 (sr:pseudomonas putida (strain ppg2) dna) (de:pseudomonas putida branched-chain keto acid dehydrogenase operon(bkda1, bkda1 and bkda2), transacylase e2 (bkdb), bkdr andlipoamide dehydrogenase (lpdv) genes, complete cds.) 21986702_f2_22 84 16655 2934 977 432 −39 Pseudomonas putida P09062 (ec:2.3.1.—) (de:chain transacylase)) 14975718_f2_23 85 16656 441 146 110 −6 Klebsiella Contig527A GTC ORF with score 168 to: pneumoniae (ai:7000807184) (or:Pseudomonas aeruginosa) 32204137_f2_24 86 16657 978 325 107 −3 mice|C57BL/6xCBA/ S04336 (c1:unassigned ribonucleoprotein CaJ hybrid repeat-containing proteins: ribonucleoprotein repeat homology) (sr:, house mouse) 16933157_f3_27 87 16658 762 253 374 −36 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 149/162.) (nt:rv3537, (mtcy03c7.19c), len: 563 aa. similar eg to) 32596957_f3_28 88 16659 1353 450 135 −6 Rattus norvegicus B39066 (c1:proline-rich protein) (sr:, norway rat) 6738891_f3_30 89 16660 1395 464 1730 −178 Pseudomonas putida P09060 (ec:1.2.4.4) (de:(bckdh e1-alpha)) 34613530_f3_32 90 16661 1065 354 1162 −118 Pseudomonas putida P09062 (ec:2.3.1.—) (de:chain transacylase)) 22150333_f3_33 91 16662 1398 465 1743 −179 Pseudomonas putida P09063 (ec:1.8.1.4) (de:dehydrogenase) (lpd-val)) 3160032_f3_35 92 16663 1206 401 832 −83 Bacillus Q45068 (de:amino acid carricr protein alst) subtilis/Bacillus globigii 32522792_c1_42 93 16664 753 250 152 −8 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene, complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 30369762_c1_44 94 16665 756 251 101 −3 Alphaherpesvirus P52506 (sr:indiana-funkhauser/becker, prv) pseudorabies virus (ec:3.2.2.—) (de:uracil-dna PRV glycosylase, (udg)) 6439575_c1_51 95 16666 324 107 94 −6 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 159/162.) (nt:rv3850, (mtcy01a6.18c), len: 218. unknown.) 16304783_c2_57 96 16667 1158 385 243 −21 Enterobacter cloacae CONTIG393 GTC ORF with score 348 to: (ai:7501750253) (or:Klebsiella pneumoniae) 22681466_c2_58 97 16668 549 182 14868913_c2_59 98 16669 1038 345 164 −10 Klebsiella Contig530A GTC ORF with score 1135 to: pneumoniae (ai:7000842307) (or:Enterobacter cloacae) 2082901_c2_60 99 16670 993 330 151 −8 Enterobacter cloacae CONTIG484 GTC ORF with score 1098 to: (ai:7501740473) (or:Klebsiella pneumoniae) 3254126_c2_61 100 16671 669 222 104 −3 Rattus norvegicus M64793 (sr:rat (sprague-dawley) liver dna) (de:rat salivary proline-rich protein (rp15) gene, complete cds.) 22464186_c2_65 101 16672 480 159 321 −29 Pseudomonas putida P42179 (de:bkd operon transcriptional regulator) 10050816_c3_77 102 16673 846 281 107 −6 Staphylococcus CONTIG030 GTC ORF with score 179 to: epidermidis C (ai:4500688693) (or:Enterococcus faccalis) 12791456_c3_79 103 16674 483 160 140 −10 Enterobactcr cloacae CONTIG484 GTC ORF with score 465 to: (ai:7501740484) (or:Klebsiella pneumoniae) 11213183_c3_80 104 16675 1629 542 35664792_c3_84 105 16676 630 209 126 −5 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:cbna-1 nuclear protein) 31656308_f1_8 106 16677 408 135 124 −8 Hordeum vulgare X68600 (sr:barley) (de:h. vulgare pze40 gene.) 4777041_f2_16 107 16678 624 207 250 −21 Acinetobacter CONTIG170 GTC ORF with scorc 250 to: baumannii C (ai:7000757116) (or:Pseudomonas aeruginosa) 6770808_f3_20 108 16679 2664 887 5181283_f3_23 109 16680 1713 570 749 −74 Acinetobacter CONTIG170 GTC ORF with scorc 749 to: baumannii C (ai:7000757123) (or:Pseudomonas aeruginosa) 31289543_c1_30 110 16681 1293 430 12365831_c1_31 111 16682 585 195 113 −4 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, complete cds.) 26649143_c2_37 112 16683 549 182 117 −4 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 32517041_c2_38 113 16684 2553 851 655 −64 Escherichia coli B64836 29298930_c3_39 114 16685 495 164 125 −8 Plasmid pAH4 JC2322 24900040_c3_41 115 16686 663 220 123 −5 Nephila clavipes U20329 (fn:spider silk) (de:nephila clavipes spidroin 1 mrna, partial cds.) (nt:fibroin) 16494831_c3_42 116 16687 432 143 136 −9 Aquifex aeolicus G70322 34479187_f1_2 117 16688 249 82 123 −7 Xanthomonas Z95386 (de:x.campestris exbd1, exbd2, exbb campestris and tonb genes.) 10410181_f1_3 118 16689 495 164 132 −8 Chlamydomonas S50755 reinhardtii strain UTEX 1061 11980342_f1_4 119 16690 417 138 263 −23 Neisseria U79563 (de:neisseria gonorrhoeae tonb gonorrhoeae (tonb), exbb (exbb) and exbd (exbd) genes, complete cds.) 15911466_f1_8 120 16691 2457 818 690 −68 Klebsiella U95087 (fn:involved in biosynthesis of the pneumoniae prosthetic) (de:klebsiella pneumoniae malonate decarboxylase gene cluster (mdca, mdcb, mdcc, mdcd, mdce, mdcf, mdcg, mdch, mdcr) genes, complete cds.) (nt:similar to citg proteins of citrate lyases f . . . 6353840_f1_10 121 16692 279 92 168 −13 Enterobactcr cloacae CONTIG457 GTC ORF with score 301 to: (ai:7501783383) (or:Klebsiella pneumoniae) 16145756_f1_12 122 16693 822 273 157 −8 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 35251001 _f1_13 123 16694 417 138 128 −7 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 13016666_f1_14 124 16695 519 172 298 −26 Klebsiella U56096 (fn:unknown) (de:klebsiella pneumoniae pneumoniae mdca, mdcb, mdcc, mdcd, mdce, mdcf, and mdcg, genes, complete cds.) (nt:similar to malonyl coa-acyl carrier protein) 15711007_f2_17 125 16696 825 274 92 −3 Enterobacter cloacae CONTIG292 GTC ORF with score 92 to: (ai:7000757163) (or:Pseudomonas aeruginosa) 13160950_f2_21 126 16697 1728 575 2207 −229 Klebsiella U95087 (de:klebsiella pneumoniac malonate pneumoniae decarboxylase gene cluster (mdca, mdcb, mdcc, mdcd, mdce, mdcf, mdcg, mdch, mdcr) genes, complete cds.) (nt:acyl carrier protein transferase: alpha subunit of) 12359582_f2_23 127 16698 396 131 268 −23 Klebsiella U95087 (de:klebsiella pneumoniae pneumoniae malonate decarboxylase gene cluster (mdca, mdcb, mdcc, mdcd, mdce, mdcf, mdcg, mdch, mdcr) genes, complete cds.) (nt:acyl carrier protein; delta subunit of malonate) 3308541_f2_24 128 16699 510 169 104 −4 Klebsiella Contig501A GTC ORF with scorc 1258 to: pneumoniae (ai:1500687053) (or:Escherichia coli) (ec:2.7.4.7) (de:(hmp-p kinase)) 2525893_f2_25 129 16700 975 324 758 −75 Klebsiella U56096 (fn:putative enzyme subunit involved pneumoniae in malonate) (de:klebsiella pneumoniae mdca, mdcb, mdcc, mdcd, mdce, mdcf, and mdcg, genes, complete cds.) (nt:an acetyl coenzyme a carboxylase carboxyl) 32635752_f2_26 130 16701 708 235 342 −31 Klebsiella U95087 (fn:involved in formation of thc pneumoniae holo-acyl carrier) (de:klebsiella pneumoniae malonate decarboxylase gene cluster (mdca, mdcb, mdcc, mdcd, mdce, mdcf, mdcg, mdch, mdcr) genes, complete cds.) 11911025_f3_28 131 16702 1083 360 347 −31 Xanthomonas Z95386 (de:x. campestris exbd1, exbd2, exbb campestris and tonb genes.) 1974136_f3_29 132 16703 717 238 105 −3 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpesvirus papio brrf2 homolog gene, partial cds, ebna1, bkrf2homolog and bkrf3 homolog genes, complete cds, and homolog gene, partial cds.) (nt:similar to ebna1 of epstein-barr v . . . 5012_f3_30 133 16704 660 219 210 −17 Clostridium Z96934 (de:clostridium beijerinekii beijerinekii fms gene.) 10819842_f3_33 134 16705 513 170 120 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12348955_f3_34 135 16706 1029 342 183 −12 Orf virus B34768 16929207_f3_35 136 16707 1011 336 968 −97 Klebsiella U95087 (de:klebsiella pneumoniae malonate pneumoniae decarboxylase gene cluster (mdca, mdcb, mdcc, mdcd, mdce, mdcf, mdcg, mdch, mdcr) genes, completecds.) (nt:decarboxylase subunit; beta subunit of malonate) 30562584_c1_40 137 16708 1209 402 156 −11 Enterobacter cloacae CONTIG457 GTC ORF with score 156 to: (ai:7000757186) (or:Pseudomonas aeruginosa) 16980201 _c1_47 138 16709 819 272 261 −23 Klebsiella Contig541A GTC ORF with score 261 to: pneumoniae (ai:7000757193) (or:Pseudomonas aeruginosa) 35659652_c1_48 139 16710 402 133 460 −44 Klebsiella Contig541A GTC ORF with score 460 to: pneumoniae (ai:7000757194) (or:Pseudomonas aeruginosa) 16058203_c1_50 140 16711 426 141 382 −35 Enterobacter cloacae CONTIG457 GTC ORF with score 432 to: (ai:7501783623) (or:Klebsiella pneumoniae) 34114655_c1_53 141 16712 312 103 26603958_c2_58 142 16713 249 82 154 −11 Klebsiella Contig541A GTC ORF with score 154 to: pneumoniae (ai:7000757204) (or:Pseudomonas aeruginosa) 14332833_c2_59 143 16714 429 142 117 −5 Alphaherpesvirus P33479 (sr:kaplan, prv) (de:immediate-early protein pseudorabies virus ie180) PRV 32682280_c2_62 144 16715 2073 690 140 −6 Homo sapiens S16506 (sr:, man) 15102041_c2_63 145 16716 501 166 134 −7 human herpesvirus U13194 (fn:transcriptional regulation) type 6 HHV-6 (de:human herpesvirus 6 replication origin-binding protein (hdrfo), partial cds, helicase-primase component (hdrf1), virion protein (hdlf1), putative helicase (hdrf2), putative phosphoprotein(edrf1), replica . . . 9863400_c2_70 146 16717 1035 344 159 −10 Enterobacter cloacae CONTIG473 GTC ORF with score 140 to: (ai:236122) (or:Escherichia coli) (sr:escherichia coli dna) (de:escherichia coli tolqra gene cluster dna.) (nt:orf4; putative) 17081408_c3_72 147 16718 1038 345 107 −2 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 26031633_c3_73 148 16719 936 311 424 −40 Klebsiella Contig541A GTC ORF with score 612 to: pneumoniae (ai:7000830999) (or:Enterobacter cloacae) 10817541_c3_74 149 16720 984 327 112 −6 longfin squid S56117 (sr:, longfin squid) 12595843_c3_76 150 16721 1908 635 713 −71 Klebsiella Contig541A GTC ORF with score 713 to: pneumoniae (ai:7000757222) (or:Pseudomonas aeruginosa) 24707281_f1_1 151 16722 540 179 119 −5 Nephila clavipes AF027973 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 20992033_f1_2 152 16723 1419 472 10400468_f1_6 153 16724 1029 342 377 −35 Bradyrhizobium AF007569 (de:bradyrhizobium japonicum gstr japonicum (gstr) gene, partial cds, and succinate dehydrogenase membrane anchor subunit (sdhc), membrane anchor subunit (sdhd), flavoprotein subunit (sdha) and iron-sulfurprotein subunit (sdhb) genes, complete c . . . 14338332_f1_8 154 16725 1176 391 243 −19 Klebsiella Contig547A GTC ORF with score 243 to: pneumoniae (ai:7000757234) (or:Pseudomonas aeruginosa) 13105413_f1_10 155 16726 1686 561 679 −67 Escherichia coli P24217 (ec:2.7.1.69) (de:hpr) (ciii-fru) (fructose pts diphosphoryl transfer protein)) 34455281_f1_16 156 16727 567 188 144 −10 Escherichia coli P32673 (ec:2.7.1.69) (de:ii, b component),) 4941456_f2_17 157 16728 1692 563 1912 −197 Pseudomonas P28812 (de:hypothetical protein in mmsb 3′ aeruginosa region (orf1) (fragment)) 32227268_f2_18 158 16729 1455 484 343 −31 Enterobacter cloacae CONTIG469 GTC ORF with score 343 to: (ai:7000757244) (or:Pseudomonas aeruginosa) 30339468_f2_22 159 16730 495 164 160 −10 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 10395933_f2_27 160 16731 390 129 98 −5 longfin squid S56117 (sr:, longfin squid) 15755381_f2_29 161 16732 1041 346 257 −22 Haemophilus P44330 (ec:2.7.1.56) (de:1- influenzae phosphofructokinase, (fructose 1-phosphate kinase)) 34114468_f3_36 162 16733 1074 357 128 −8 Klebsiella Contig542A GTC ORF with score 128 to: pneumoniae (ai:7000757262) (or:Pseudomonas aeruginosa) 20210312_f3_38 163 16734 1251 416 172 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 16503555_f3_39 164 16735 807 268 223 −19 Enterobacter cloacae CONTIG469 GTC ORF with score 495 to: (ai:7501735739) (or:Klebsiella pneumoniae) 21877318_f3_42 165 16736 1320 439 241 −17 Murine herpesvirus U97553 (de:murine herpesvirus 68 strain 68 wums, complete genome.) 13023957_f3_43 166 16737 1560 519 1004 −101 Rhodobacter P23388 (sr:, rhodopseudomonas capsulata) capsulatus (ec:2.7.3.9:2.7.1.69) (de:(eiii-fru))) 16928841_f3_44 167 16738 780 259 385 −35 Escherichia coli P23539 (ec:2.7.1.56) (de:1- phosphofructokinase, (fructose 1-phosphate kinase)) 16910055_c1_49 168 16739 663 220 158 −12 Klebsiella Contig245A GTC ORF with scorc 158 to: pneumoniae (ai:7000757275) (or:Pseudomonas aeruginosa) 15678905_c1_51 169 16740 363 120 132 −7 Rana catesbeiana D88764 (sr:rana catesbeiana larva tail cdna to mrna) (de:rana catesbeiana mrna for alpha 2 type i collagen, complete cds.) 32676943_c1_53 170 16741 1803 600 169 −12 Enterobacter cloacae CONTIG266 GTC ORF with score 209 to: (ai:7501730540) (or:Klebsiella pneumoniae) 13087530_c1_54 171 16742 1032 343 699 −69 Escherichia coli P21168 (de:fructose repressor (catabolite repressor/activator)) 22130408_c1_55 172 16743 948 315 149 −8 Homo sapiens S62928 (sr:human salivary) (de:prb1m=prb1 medium length copy {exon 3} (human, salivary, genomic, 924 nt).) (nt:basic proline-rich proteins (ps, pmf, pms, and pe)) 33689590_c1_56 173 16744 1110 369 361 −33 Klebsiella Contig501A GTC ORF with score 361 to: pneumoniae (ai:7000757282) (or:Pseudomonas aeruginosa) 12127218_c2_63 174 16745 1176 391 100 −2 Enterobacter cloacae CONTIG266 GTC ORF with score 572 to: (ai:7501730539) (or:Klebsiella pneumoniae) 10835080_c2_64 175 16746 2610 869 244 −17 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14557080_c2_67 176 16747 891 296 502 −48 Escherichia coli P39408 (de:hypothetical 28.9 kd protein in osmy-deoc intergenic region) 4395776_c2_70 177 16748 633 210 92 −3 common sunflower S46272 (sr:, common sunflower) 12369441_c2_72 178 16749 528 175 124 −6 Homo sapiens PN0099 (sr:, man) 12191068_c3_73 179 16750 501 166 118 −5 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 31755291_c3_74 180 16751 1461 486 171 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 9846943_c3_75 181 16752 828 275 127 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12350785_c3_81 182 16753 999 332 115 −4 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16260280_c3_82 183 16754 1611 536 236 −17 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 21484756_c3_83 184 16755 354 117 142 −10 Bacillus P94425 (de:hypothetical 10.9 kd protein) subtilis/Bacillus globigii 11728918_c3_84 185 16756 1035 344 336 −30 Streptomyces AF072709 (de:streptomyces lividans amplifiable lividans element aud4: putative transcriptional regulator, putative ferredoxin, putative cytochromep450 oxidoreductase, and putative oxidoreductase genes, complete cds; and unknown genes.) (nt:orf9; similar . . . 12788582_c3_85 186 16757 1698 565 326 −27 Klebsiella Contig499A GTC ORF with score 1051 to: pneumoniae (ai:7000798862) (or:Pseudomonas aeruginosa) 33869656_f1_4 187 16758 1317 438 138 −5 Schizosaccharomyce P40976 (sr:, fission yeast) (ec:1.2.1.31) s pombe de:aminoadipate reductase) (alpha-ar)) 31895753_f1_8 188 16759 348 115 151 −11 Klebsiella Contig253A GTC ORF with score 151 to: pneumoniae (ai:7000757319) (or:Pseudomonas aeruginosa) 35650293_f1_12 189 16760 1101 366 838 −83 Escherichia coli P32066 (de:hypothetical 41.9 kd protein in fucr-gcva intergenic region (orf3)) 11072968_f1_13 190 16761 324 107 205 −16 Escherichia coli P37618 (de:hypothetical 9.1 kd protein in ftsy-nika intergenic region) 31847590_f1_28 191 16762 1014 338 552 −53 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna, c1:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position (6/7).) 4774205_f2_30 192 16763 693 230 137 −7 Caenorhabditis AF000198 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 32675683_f2_33 193 16764 1698 565 176 −11 Enterobacter cloacae CONTIG490 GTC ORF with score 300 to: (ai:7000797020) (or:Pseudomonas aeruginosa) 35449062_f2_34 194 16765 2784 927 558 −53 Klebsiella Contig253A GTC ORF with score 558 to: pneumoniae (ai:7000757345) (or:Pseudomonas aeruginosa) 5178955_f2_36 195 16766 1014 337 91 −2 Klebsiella Contig519A GTC ORF with score 275 to: pneumoniae (ai:7000787170) (or:Pseudomonas aeruginosa) 3306418_f2_37 196 16767 408 135 149 −10 Klebsiella Contig532A GTC ORF with score 632 to: pneumoniae (ai:7000771478) (or:Pseudomonas aeruginosa) 10259456_f2_39 197 16768 1488 495 179 −13 Klebsiella Contig532A GTC ORF with score 181 to: pneumoniae (ai:7000795298) (or:Pseudomonas aeruginosa) 35572936_f2_49 198 16769 1020 339 136 −7 mice|C57BL/6xCBA/ P26687 (sr:,mouse) (de:twist related CaJ hybrid protein (m-twist)) 31453387_f3_53 199 16770 690 229 221 −20 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 21/162.) (nt:rv0421c, (mtcy22g10.18c), len: 209, unknown) 1432630_f3_55 200 16771 1182 393 127 −5 Dissostichus U43149 (de:dissostichus mawsoni antifreeze mawsoni glycopeptide afgp polyproteinprecursor gene, complete cds.) 15836706_f3_64 201 16772 411 136 104 −6 Klebsiella Contig544A GTC ORF with score 160 to: pneumoniae (ai:69657) (or:Human herpesvirus 4) (cl:epstein-barr virus nuclear antigen) 12900407_f3_73 202 16773 810 269 116 −5 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(micc, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 10972567_f3_75 203 16774 888 295 371 −34 Chromatium P25544 (de:rubisco operon transcriptional vinosum regulator) 14332715_f3_77 204 16775 618 206 158 −10 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:cbna-1 nuclear protein) 13020905_c1_79 205 16776 501 166 160 −10 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 162537_c1_81 206 16777 1890 629 256 −20 Chlamydia AE001273 (de:chlamydia trachomatis section trachomatis 52 of 87 of the complete genome.) 12978830_c1_82 207 16778 1434 477 495 −47 Streptomyces AL031225 (de:streptomyces coelicolor cosmid coelicolor 8b7.) (nt:sc8b7.07c, possible oxidoreductase,: 475 aa;) 34478965_c1_85 208 16779 591 196 155 −10 equine herpesvirus D88734 (sr:equine herpesvirus 1 type 1 EVH-1 (strain:bk343, isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 30598783_c1_86 209 16780 357 118 126 −7 Pseudomonas putida D85415 (sr:pseudomonas putida (strain:ucc22) dna) (de:pseudomonas putida gene for conversion of aniline to catechol.) (nt:amino group transfer) 21772952_c1_90 210 16781 1146 381 279 −25 Enterobacter cloacae CONTIG456 GTC ORF with score 376 to: (ai:7501743772) (or:Klebsiella pneumoniae) 33850706_c1_92 211 16782 516 171 138 −9 Homo sapiens A48018 (sr:, man) (mp:4q13-4q21) 12002018_c1_97 212 16783 447 148 138 −9 southern root-knot U68729 (sr:southern root-knot nematode) nematode (de:meloidogyne incognita cuticle preprocollagen (col-2) mrna, complete cds.) 30682032_c2_100 213 16784 615 204 100 −5 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna, c1:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) 29869505_c2_104 214 16785 1077 358 211 −16 Rickettsia AJ235269 Rickettsia prowazekii strain prowazckii Madrid E, complete genome. 182312_c2_109 215 16786 255 84 22133333_c2_111 216 16787 756 251 132 −6 Klebsiella Contig554A GTC ORF with score 1366 to: pneumoniae (ai:71316) (or:Escherichia coli) (de:escherichia coli genomic sequence of minutes 9 to 12.) 25495906_c2_112 217 16788 1425 474 104 −1 mice|C57BL/6xCBA/ U76716 (sr:house mouse) (de:mus musculus CaJ hybrid voltage-sensitive calcium channel alpha 1 a (ccha1 a)mrna, complete cds.) (nt:ion channel) 35254591 _c2_117 218 16789 2325 774 155 −7 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 562702_c2_119 219 16790 1701 566 149 −6 Homo sapiens M96943 (sr:homo sapiens (library: emb13, clonetics) epidermal dna) (de:human profilaggrin gene exons 1-3, 5′ end. 29566530_c2_121 220 16791 1317 438 29960456_c3_126 221 16792 318 105 33675666_c3_129 222 16793 270 89 32522705_c3_131 223 16794 516 171 233 −19 Haemophiius C64173 influenzae 22145213_c3_132 224 16795 1506 501 92 −3 Hordeum vulgare X68600 (sr:barley) (de:h. vulgare pze40 gene.) 21738400_c3_133 225 16796 3114 1037 799 −79 Escherichia coli P37906 (ec: 1.—.—.—) (de:probable oxidoreductase ord1,) 33721007_c3_136 226 16797 357 118 95 −4 Caenorhabditis AF000198 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticuiar collagen) 14703217_c3_138 227 16798 2946 981 2872 −299 Xanthomonas AJ002070 (fn:regulator of pathogenicity factors campestris and) (ec:4.2.1.3) (de:xanthomonas campestris rpfa gene, complete.) 35833418_c3_139 228 16799 1938 645 1035 −104 Escherichia coli JQ1475 (cl:methyl-accepting chemotaxis protein) 26605081_c3_145 229 16800 927 308 948 −95 Rhizobium Z80339 (fn:subunit i of terminal cytochrome leguminosarum c oxidase) (de:r. leguminosarum fixnd and fixod genes.) 13175818_f1_1 230 16801 684 227 216 −18 Klebsiella Contig522A GTC ORF with score 323 to: pneumoniae (ai:7000829656) (or:Enterobacter cloacae) 16307666_f1_2 231 16802 1962 653 1064 −107 Cyanobacterium S77243 (sr:pcc 6803, , pcc 6803) synechocystis (sr:pcc 6803,) 26048818_f1_3 232 16803 786 261 181 −12 silkworm S42886 (c1:unassigned collagens) (sr:, silkworm) 5192913_f1_5 233 16804 543 180 200 −16 Enterobacter cloacae CONTIG248 GTC ORF with score 200 to: (ai:7000757461) (or:Pseudomonas aeruginosa) 7300803_f1_7 234 16805 198 65 10182080_f1_11 235 16806 465 154 90 −2 Homo sapiens Y13709 (sr:human) (de:homo sapiens caudal-type homeobox gene 2 (cdx2) sequence.) 22944501 _f1_16 236 16807 633 210 97 −2 Caenorhabditis AF026211 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid t13b5.) (nt:similar to cuticular collagen) 35285207_f1_19 237 16808 894 297 390 −36 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssua) 31899130_f1_20 238 16809 2076 691 1162 −118 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssuc) 34459405_f1_22 239 16810 444 147 319 −28 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssuf) 17049033_f1_27 240 16811 777 258 105 −2 Mycobacterium AL021942 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 29/162.) (nt:rv0578c, (mtv039.16c), len: 1306. member of) 11064775_f1_28 241 16812 525 174 267 −23 Escherichia coli B65061 (cl:mioc protein) 31752281_f2_31 242 16813 615 204 118 −4 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 33839080_f2_32 243 16814 456 151 125 −7 Dictyostelium P14328 (sr:, slime mold) (de:spore coat discoideum protein sp96) 9766458_f2_37 244 16815 696 231 370 −34 Escherichia coli P29217 (de:hypothetical 24.2 kd protein in rimj-mvim intergenic region (g20.3)) 14547965_f2_42 245 16816 669 222 1007 −101 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) 31338262_f2_44 246 16817 1590 529 184 −11 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 24510091_f2_45 247 16818 894 297 494 −47 Bacillus G69816 subtilis/Bacillus globigii 12697956_f2_47 248 16819 1941 646 1848 −191 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssud) 34503957_f2_49 249 16820 1017 338 153 −8 Pseudomonas A36128 aeruginosa 7204092_f3_61 250 16821 1200 399 111 −3 Caenorhabditis Z81503 (de:caenorhabditis elegans cosmid elegans f14f7, complete sequence.) (nt:predicted using genefinder; similar to collagen;) 31353580_f3_63 251 16822 1275 424 905 −91 Bacillus D70021 subtilis/Bacillus globigii 7164581_f3_65 252 16823 1737 578 478 −46 Klebsiella Contig541A GTC ORF with score 478 to: pneumoniae (ai:7000757521) (or:Pseudomonas aeruginosa) 22129126_f3_68 253 16824 1062 353 385 −35 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssua) 33650283_f3_69 254 16825 828 275 591 −57 Bacillus P40401 (de:probable abc transporter permease subtilis/Bacillus protein (orf1)) globigii 12206568_f3_72 255 16826 606 201 705 −69 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssue) 31894155_f3_73 256 16827 513 170 94 −2 Aspergillus Contig2120 GTC ORF with score 130 to: fumigatus (ai:58877) (or:Emericella nidulans) (sr:, aspergillus nidulans) (de:sterigmatocystin biosynthesis regulatory protein) 12230380_f3_74 257 16828 417 138 513 −49 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssua) 10270830_f3_75 258 16829 516 171 148 −11 Klebsiella Contig450A GTC ORF with score 148 to: pneumoniae (ai:7000757531) (or:Pseudomonas aeruginosa) 16823878_f3_76 259 16830 1524 507 1117 −113 Pseudomonas putida AF075709 (de:pseudomonas putida lsfa (lsfa), complete cds; and ssu locus, complete sequence.) (nt:ssub) 33650342_f3_79 260 16831 756 251 294 −26 Synechococcus sp. U59236 (de:synechococcus pcc7942 (strain PCC 7942) ribosomal protein s1 of 30s ribosome (rps1), orf271, orf231, orf341, carboxyltransferase alpha subunit (acca), orf245, orf227, and gtp cyclohydrolase i (fole) genes, complete cds, and orf205 gene, partial cds,) (pt . . . 19714783_c1_86 261 16832 810 269 196 −15 Syncchococcus sp. P37372 (sr:pcc 7942, anacystis nidulans r2) (de:hypothetical 23.0 kd protein in syna 5′ region (orf2) 31424137_c1_89 262 16833 486 161 244 −21 Mucuna hassjoo S54845 (ec:3.5.4.16) 31298912_c1_93 263 16834 471 156 130 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 1301681_c1_94 264 16835 831 276 151 −11 Enterobacter cloacae CONTIG375 GTC ORF with score 151 to: (ai:7000757550) (or:Pseudomonas aeruginosa) 5276706_c1_95 265 16836 504 167 456 −43 Klebsiella Contig450A GTC ORF with score 456 to: pneumoniae (ai:7000757551) (or:Pseudomonas aeruginosa) 16886542_c1_98 266 16837 465 154 132 −8 Klebsiella Contig496A GTC ORF with score 193 to: pneumoniae (ai:7000807650) (or:Pseudomonas aeruginosa) 17057067_c1_100 267 16838 402 133 137 −10 Klebsiella Contig385A GTC ORF with scorc 552 to: pneumoniae (ai:7000831233) (or:Enterobacter cloacae) 14666267_c1_104 268 16839 735 244 112 −6 Aspergillus Contig7664 GTC ORF with score 112 to: fumigatus (ai:7000757560) (or:Pseudomonas aeruginosa) 479756_c1_114 269 16840 1140 380 673 −66 Escherichia coli B65005 35331963_c2_120 270 16841 1290 429 593 −58 Cyanobacterium Q55759 (sr:pcc 6803,) (cc:3.5.4.16) (de:gtp synechocystis cyclohydrolase i, (gtp-ch-i)) 14972886_c2_121 271 16842 813 270 334 −30 Methylobacterium U87316 (de:methylobacterium extorquens extorquens putative glycerate kinase and pyruvatekinase (pyka) genes, complete cds.) (nt:orf2; putative) 17051418_c2_122 272 16843 390 129 35558537_c2_124 273 16844 813 270 106 −3 Mycobacterium AF027770 (de:mycobacterium smegmatis iron smegmatis uptake genes, fxba (fxba) gene, partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc (fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf) genes, complete cds.) (nt:similar to membrane b . . . 33792902_c2_125 274 16845 495 164 377 −35 Klebsiella Contig450A GTC ORF with score 377 to: pneumoniae (ai:7000757581) (or:Pseudomonas aeruginosa) 29585126_c2_126 275 16846 453 150 119 −6 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 6111393_c2_129 276 16847 672 223 309 −28 Klebsiella Contig450A GTC ORF with score 309 to: pneumoniae (ai:7000757585) (or:Pseudomonas aeruginosa) 31891431_c2_132 277 16848 816 271 166 −11 Klebsiella Contig506A GTC ORF with score 104 to: pneumoniae (ai:7500984984) (or:Dictyostelium discoideum) (sr:dictyostelium discoideum (str:ax2) dna) (de:dictyostelium discoideum gene for trfa, complete cds.) 32604540_c2_133 278 16849 1200 399 157 −9 Klebsiella Contig496A GTC ORF with score 209 to: pneumoniae (ai:7000807650) (or:Pseudomonas aeruginosa) 26344162_c2_135 279 16850 1737 578 1854 −191 Escherichia coli P33940 (de:hypothetical 60.2 kd protein in eco-alkb intergenic region) 32661416_c2_136 280 16851 435 144 119 −8 Klebsiella Contig554A GTC ORF with score 112 to: pneumoniae (ai:6000692284) (or:Physarum polycephalum) (sr:slime mold) (de:physarum polycephalum dna topoisomerase i (top 1) mrna, complete cds.) 26694468_c2_137 281 16852 1785 594 159 −11 Klebsiella Contig347A GTC ORF with score 349 to: pneumoniae (ai:7000795297) (or:Pseudomonas aeruginosa) 29926906_c2_142 282 16853 411 136 105 −6 Enterobacter cloacae CONTIG449 GTC ORF with score 105 to: (ai:7000757598) (or:Pseudomonas aeruginosa) 23690807_c3_144 283 16854 870 289 166 −9 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 135916_c3_145 284 16855 780 259 518 −50 Escherichia coli P52109 (ec:1.—.—.—) (de:(ec 1.—.—.—)) 573282_c3_146 285 16856 387 128 91 −3 Schizosaccharomyce Z95620 (sr:fission yeast) (de:s. pombe s pombe chromosome ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 16695455_c3_147 286 16857 390 129 370 −34 Escherichia coli P80449 (ec:5.—.—.—) (de:(dihydroneopterin triphosphate 2′-epimerase) 13144683_c3_149 287 16858 432 143 96 −2 Drosophila Q05319 (sr:, fruit fly) (ec:3.4.21.—) melanogaster (de:serine proteinase stubble, (stubble-stubbloid protein)) 32597917_c3_150 288 16859 837 278 149 −7 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 15913330_c3_153 289 16860 1365 454 475 −45 Klebsiella Contig450A GTC ORF with score 475 to: pneumoniae (ai:70000757609) (or:Pseudomonas aeruginosa) 1417537_c3_155 290 16861 417 138 179 −14 Klebsiella Contig496A GTC ORF with score 209 to: pneumoniae (ai:7000807650) (or:Pseudomonas aeruginosa) 10276086_c3_158 291 16862 993 330 209 −17 Klebsiella Contig545A GTC ORF with score 598 to: pneumoniae (ai:7000845728) (or:Enterobacter cloacae) 22146033_c3_159 292 16863 447 148 96 −2 Leishmania U78522 (de:leishmania donovani histidine (Leishmania) secretory acid phosphatase (sacp-1) donovani gene, complete cds.) 12987962_c3_161 293 16864 780 259 177 −12 Aspergillus Contig5048 GTC ORF with score 177 to: fumigatus (ai:7000757617) (or:Pseudomonas aeruginosa) 32660331_c3_167 294 16865 492 163 230 −19 Klebsiella Contig560A GTC ORF with score 106 to: pneumoniae (ai:1500692508) (or:Borcogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 30364786_c3_169 295 16866 426 141 105 −4 Alphaherpesvirus P11675 (sr:indiana-funkhauser/beckcr, prv) pseudorabies virus (de:immediate-early protein ie180) PRV 10651012_c3_170 296 16867 1041 347 105 −2 Acanthamoeba P10569 (sr:,amoeba) (de:myosin ic heavy castellanii chain) 16272582_f1_3 297 16868 510 169 112 −4 Klebsiella Contig465A GTC ORF with score 123 to: pneumoniae (ai:7000702062) (de:pseudomonas fluorescens alkaline protease, protease inhibitor, zinc-protease transporter (aprd), zinc-protease transporter (apre), and zinc-protease transporter (aprf) genes complete cds.) 1448462_f1_13 298 16869 729 242 286 −25 Escherichia coli P77216 (de:hypothetical 47.8 kd protein in csta-dsbg intergenic region) 15752316_f1_16 299 16870 672 223 156 −9 Enterobacter cloacae CONTIG450 GTC ORF with score 1547 to: (ai:7000795773) (or:Pseudomonas aeruginosa) 24112581_f1_17 300 16871 444 147 124 −7 Enterobacter cloacae CONTIG412 GTC ORF with score 304 to: (ai:7000758236) (or:Pseudomonas aeruginosa) 22913252_f1_18 301 16872 2337 778 133 −6 Klebsiella Contig536A GTC ORF with score 662 to: pneumoniae (ai:7000758235) (or:Pseudomonas aeruginosa) 25502061_f1_28 302 16873 402 133 21535400_f1_31 303 16874 1959 652 163 −11 Aspergillus Contig7727 GTC ORF with score 163 to: fumigatus (ai:7000757657) (or:Pseudomonas aeruginosa) 31379825_f1_35 304 16875 1380 459 872 −87 Ralstonia eutropha X99639 (fn:transport of 4-methylmuconolactone) (de:ralstonia eutropha mmlh, mmli & mmlj genes.) (nt:putative) 31847283_f1_36 305 16876 1254 417 951 −95 Pseudomonas putida AF029714 (de:pseudomonas putida repressor (phan), regulatory protein (pham), enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad), phenylacetyl-coa ligase (phae), ring-oxidation 5917638_f2_41 306 16877 2250 749 113 −3 Euprymna scolopes JN0867 31760430_f2_47 307 16878 843 280 356 −32 Escherichia coli P77216 (de:hypothetical 47.8 kd protein in csta-dsbg intergenic region) 4401568_f2_49 308 16879 645 214 534 −51 Escherichia coli P77174 (de:hypothetical 23.9 kd protein in csta-dsbg intergenic region) 16901087_f2_51 309 16880 759 252 183 −14 Azospirillum X70360 (de:a. brasilense carr gene.) (nt:orf2) brasilense 11183441_f2_58 310 16881 606 201 105 −3 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 33397215_f2_59 311 16882 1008 335 187 −11 mice|C57BL/6xCBA/ A45748 (cl:unassigned collagens) CaJ hybrid (sr:, house mouse) 4380068_f2_61 312 16883 1110 369 1709 −176 Ralstonia eutropha P14940 (ec:1.1.1.1) (de:alcohol dehydrogenase,) 6511542_f2_62 313 16884 777 258 157 −10 mice|C57BL/6xCBA/ A24264 (cl:proline-rich protein) CaJ hybrid (sr:, housc mouse) 35364182_f2_63 314 16885 402 133 117 −6 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene, complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 31378965_f2_64 315 16886 1014 337 32682080_f2_67 316 16887 1218 405 12994405_f2_69 317 16888 435 144 155 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22676592_f2_71 318 16889 534 177 140 −10 Klebsiella Contig349A GTC ORF with score 149 to: pneumoniae (ai:7000836613) (or:Enterobacter cloacae) 3380216_f2_72 319 16890 1026 341 318 −28 Pyrococcus AP000004 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna) (de:pyrococcus horikoshii ot3 genomic dna, 777001-994000 nt. position(4/7).) (nt:similar to swiss p:p42967 percent ident:) 26681528_f3_76 320 16891 1401 466 98 −4 Klebsiella Contig409A GTC ORF with score 98 to: pneumoniae (ai:7000757702) (or:Pseudomonas aeruginosa) 30725905_f3_86 321 16892 639 212 103 −3 Homo sapiens A47234 (cl:unassigned homeobox proteins:homeobox homology) (sr:, man) 33495655_f3_91 322 16893 774 257 100 −5 longfin squid S56117 (sr:, longfin squid) 4303193_f3_95 323 16894 915 304 442 −42 Pseudomonas AF087482 (de:pseudomonas aeruginosa clcc and aeruginosa ohbh genes, lys-r type regulatoryprotein (clcr), chlorocatechol-1,2-dioxygenase (clca), chloromuconate cycloisomerase (clcb), dienelactone hydrolase (clcd), maleylacetate reductase (clce). transposas . . . 29584653_f3_96 324 16895 576 191 371 −34 Acinetobacter CONTIG195 GTC ORF with score 371 to: baumannii C (ai:7000757722) (or:Pseudomonas aeruginosa) 10647667_f3_100 325 16896 411 136 164 −12 Klebsiella Contig117A GTC ORF with score 164 to: pneumoniae (ai:7000757726) (or:Pseudomonas aeruginosa) 32552326_f3_101 326 16897 933 310 98 −3 Klebsiella Contig117A GTC ORF with score 164 to: pneumoniae (ai:7000757726) (or:Pseudomonas aeruginosa) 12975755_f3_102 327 16898 546 181 154 −9 Caenorhabditis U80846 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 502158_f3_108 328 16899 2085 694 109 −5 longfin squid S56117 (sr:, longfin squid) 16583301_f3_109 329 16900 909 302 108 −3 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase-binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein,) 14742256_f3_110 330 16901 759 252 586 −57 Bordetella pertussis AF006000 (de:bordetella pertussis d-3-phosphoglycerate dehydrogenase homolog(scra) and brg1 (brg1) genes, complete cds.) (nt:orf7; similar to b. subtilis yesf) 12552141_c1_116 331 16902 3141 1046 137 −5 African clawed frog U85970 (sr:african clawed frog) (de:xenopus laevis middle molecular weight neurofilament proteinnf-m(2) mrna, complete cds.) (nt:neuronal intermediate filament protein; duplicated) 30682817_c1_117 332 16903 936 311 702 −69 Bacillus P42966 (de:hypothetical 28.1 kd protein in subtilis/Bacillus sipu-pbpc intergenic region) globigii 4033408_c1_119 333 16904 1422 473 135 −5 Gallus gallus A90458 (cl:collagen alpha 1(i) chain:fibrillar domesticus collagen carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 3400782_c1_122 334 16905 414 137 117 −7 Staphylococcus CONTIG080 GTC ORF with score 203 to: epidermidis C (ai:7000771238) (or:Pseudomonas aeruginosa) 36429131 _c1_126 335 16906 792 263 190 −13 Homo sapiens X98705 (sr:human) (de:h. sapiens dna sequence of collal gene fused with intron 1 of pdgfbgene.) 4315927_c1_127 336 16907 1350 449 103 −5 Klebsiella Contig532A GTC ORF with score 110 to: pneumoniae (ai:7000806016) or:Pseudomonas aeruginosa) 31723766_c1_130 337 16908 1677 558 654 −64 Rhodococcus sp. P46371 (sr:ni86/21,) (de:hypothetical 53.0 kd gmc-type oxidoreductase in thca 5′ region (orf2)) 26738456_c1_131 338 16909 1470 489 829 −83 Bacillus P71016 (ec:1.2.1.8) (de:betaine aldehyde subtilis/Bacillus dehydrogenase, (badh)) globigii 32711537_c2_148 339 16910 654 217 114 −3 Acanthamoeba P19706 (sr:, amoeba) (de:myosin heavy chain castellanii ib (myosin heavy chain il)) 25807681 _c2_149 340 16911 549 182 198 −16 Enterobacter cloacae CONTIG484 GTC ORF with score 248 to: (ai:7501736005) (or:Klebsiella pneumoniae) 13150250_c2_154 341 16912 1263 420 4588505_c2_158 342 16913 1113 370 978 −98 Escherichia coli M10315 (sr:e. coli (strain b/r) dna, clone pcs68) (de:e. coli (strain b) ada gene coding for ada polyprotein, regulatoryprotein of adaptive response.) (nt:ada polyprotein) 16275655_c2_161 343 16914 933 310 139 −7 Klebsiella Contig557A GTC ORF with score 331 to: pneumoniae (ai:7000776648) (or:Pseudomonas aeruginosa) 31720655_c2_163 344 16915 795 264 16105455_c2_164 345 16916 969 322 441 41 Haemophilus U20964 (de:haemophilus influenzae dna influenzae topoisomerase i (topa) gene, complete cds, putative pyridine nucleotide transhydrogenase beta subunit(pntb) gene, partial cds, orf2 and orf3 genes, complete cds andputative threonyl-trna synthetase (thrs) ge . . . 20973781 _c2_169 346 16917 213 70 93 −5 Enterobacter cloacae CONTIG450 GTC ORF with score 146 to: (ai:7000808962) (or:Pseudomonas aeruginosa) 35447962_c2_179 347 16918 594 197 230 −19 Escherichia coli L43373 (sr:escherichia coli (strain 31a/o6) dna) (de:escherichia coli (clone 20kpil) pilin 20k gene complete cds.) 16932077_c2_180 348 16919 834 277 398 −37 Escherichia coli L77091 (fn:stabilization of major subunit proteins) (sr:escherichia coli (individual_isoIate natural isolate, strai) (de:escherichia coli f17d fimbrial gene clustcr encoding the majorfimbrial subunit protein (f17d-a), the chaperone protein f17d . . . 22785066_c2_182 349 16920 2943 981 186 −10 Micrococcus luteus JQ0405 5156563_c3_189 350 16921 1074 357 255 −22 Bacillus C69635 subtilis/Bacillus globigii 16103956_c3_190 351 16922 2016 671 10808456_c3_192 352 16923 717 238 93 −2 Schizosaccharomyce Z95620 (sr:fission yeast) (de:s. pombe s pombe chromosome ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 2393831_c3_193 353 16924 1719 572 121 −4 Klebsiella Contig469A GTC ORF with score 476 to: pneumoniae (ai:7000841954) (or:Enterobacter cloacae) 12630068_c3_201 354 16925 1482 493 126 −7 longfin sguid S56117 (sr: longfin squid 16307276_c3_202 355 16926 1689 562 94 −1 Escherichia coli D90890 (pn:succinate-semialdehyde dehydrogenase (nadp+) (ec) (sr:eschcrichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #443(59.8-60.2 min.).) (nt:similar to swissprot accession number p25526):) 35258530_c3_203 356 16927 1014 337 190 −15 Klebsiella Contig554A GTC ORF with score 190 to: pneumoniae (ai:7000757829) (or:Pseudomonas aeruginosa) 13001666_c3_206 357 16928 678 225 130 −7 Klebsiella Contig554A GTC ORF with score 130 to: pneumoniae (ai:7000757832) (or:Pseudomonas aeruginosa) 13791555_c3_211 358 16929 2652 883 1127 −114 Escherichia coli P75857 (de:region precursor) 5183453_f1_1 359 16930 879 292 169 −11 Enterobacter cloacae CONTIG480 GTC ORF with score 707 to: (ai:7501752834) (or:Klebsiella pneumoniae) 13027080_f1_2 360 16931 501 166 824 −82 Pseudomonas P24560 (de:hypothctical 17.0 kd protein in aeruginosa pilt 5′ region (orf1)) 24713125_f1_3 361 16932 372 123 437 −41 Pseudomonas P24561 (de:hypothetical 8.9 kd protein in aeruginosa pilt 5′ region (orf2)) 11996075_fI_4 362 16933 1047 348 1728 −178 Pseudomonas P24559 (de:twitching mobility protein) aeruginosa 24817828_f1_5 363 16934 1164 387 1937 −200 Pseudomonas S54702 aeruginosa 3367078_f1_9 364 16935 1437 478 720 −71 Mycobacterium AL021897 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 48/162.) (nt:rv1077, (mtv017.30), cysm, len: 464. cysm2,) 14958408_f1_10 365 16936 429 142 138 −9 Orgyia O10341 (sr:, opmnpv) (de:hypothetical 29.3 kd protein pseudotsugata (orf92)) multinucleocapsid nuclear polyhedrosis virus OpMNPV 11744805_f1_17 366 16937 738 245 100 −2 Lysobacter A31772 (cl:streptomyces proteinase enzymogenes a:trypsin homology) (ec:3.4.21.12) 5960761_f1_26 367 16938 1347 448 103 −2 Caenorhabditis U23520 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid c35b8.) (nt:similar to cuticular collagen) 2991706_f1_28 368 16939 561 186 123 −5 Nephila clavipes AF027972 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 22439766_f1_29 369 16940 1470 489 159 −9 Caenorhabditis Z81503 (de:caenorhabditis elegans cosmid elegans f14f7, complete sequence.) (nt:predicted using genefinder similar to collagen;) 35369716_f1_31 370 16941 2019 672 213 −13 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein mispl mrna, partialcds.) 32047627_f1_32 371 16942 582 193 135 −7 Epstein-Barr virus S27923 16660458_f1_33 372 16943 561 186 167 −11 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 12321041_f1_34 373 16944 444 147 107 −6 longfin squid S56117 (sr:, longfin squid) 16484455_f1_37 374 16945 915 304 114 −4 Human P50809 (de: regulatory protein e2) papillomavirus type 36 14563156_f1_38 375 16946 618 205 259 −22 Pseudomonas U79580 (de:pseudomonas aeruginosa pilk aeruginosa gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:similar to xyls/arac protein family) 12161030_f1_39 376 16947 642 213 1050 −106 Pseudomonas U79580 (de:pseudomonas aeruginosa pilk aeruginosa gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:similar to bacillus subtilis ycgf and unknown orf) 33614582_f1_40 377 16948 522 173 103 −2 Strongylocentrotus S23809 (cl:collagen alpha 2(i) chain:fibrillar purpuratus collagen carboxyl-terminal homology) (sr:, purple urchin) 15886531_f1_42 378 16949 564 187 145 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 14145658_f1_44 379 16950 537 178 268 −23 Klebsiella Contig526A GTC ORF with score 825 to: pneumoniae (ai:7000844364) (or:Enterobacter cloacae) 17064555_f1_45 380 16951 426 141 125 −7 Caenorhabditis AF022985 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 12679763_f1_46 381 16952 1617 538 247 −20 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 137/162.) (nt:rv3170, (mtv014.14), len: 448. probable) 2541631_f1_47 382 16953 675 224 636 −62 Escherichia coli F64848 30213580_f1_55 383 16954 1584 527 2415 −251 Pseudomonas AB011381 (sr:pseudomonas aeruginosa aeruginosa (str:tnp058) dna) (de:pseudomonas aeruginosa gene for oprm, complete cds.) 30191575_f1_58 384 16955 1446 481 149 −6 Chinese oak AF083334 (sr:chinese oak silkmoth) silkmoth (de:antheraea pernyi fibroin gene, complete cds.) 10633293_f2_65 385 16956 1164 387 638 −62 Pseudomonas M55524 (sr:pseudomonas aeruginosa (strain aeruginosa paol) (library: banhi genomi) (de:pseudomonas aeruginosa twitching motility protein (pilt) gene, andorf's 1,2,4,5,6 and 7, complete cds.) nt:orf4: putative) 22784416_f2_69 386 16957 774 257 178 −14 Enterobacter cloacae CONTIG361 GTC ORF with score 178 to: (ai:7000757907) (or:Pseudomonas aeruginosa) 21619756_f2_70 387 16958 453 150 12995955_f2_71 388 16959 405 134 154 −11 Klebsiella Contig332A GTC ORF with score 263 to: pneumoniae (ai:7000822288) (or:Enterobacter cloacae) 14661633_f2_75 389 16960 291 96 245 −20 Caenorhabditis Z83106 (de:caenorhabditis elegans cosmid elegans f22b8, complete sequence.) (nt:predicted using genefinder; similar to cystathione) 7042918_f2_76 390 16961 417 138 119 −6 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 35438883_f2_80 391 16962 561 186 167 −13 Klebsiella Contig526A GTC ORF with score 237 to: pneumoniae (ai:7000844516) (or:Enterobacter cloacae) 33255461_f2_86 392 16963 471 156 681 −67 Pseudomonas P46384 (de:pilg protein) aeruginosa 31847526_f2_87 393 16964 927 308 938 −94 Pseudomonas P43502 (de:pili protein) aeruginosa 31446011_f2_88 394 16965 2091 696 3275 −9999 Pseudomonas P42257 (de:pilj protein) aeruginosa 13152083_f2_89 395 16966 912 303 1346 −137 Pseudomonas S61498 (cl:protein-glutamate aeruginosa o-methyltransferase homology) 33616093_f2_90 396 16967 7449 2482 8157 −9999 Pseudomonas U79580 (de:pseudomonas aeruginosa pilk aeruginosa gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:cheay homolog) 32605191_f2_93 397 16968 708 235 823 −82 Pseudomonas U79580 (fn:unknown) (de:pseudomonas aeruginosa aeruginosa pilk gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) 12603875_f2_102 398 16969 1995 664 289 −25 Enterobacter cloacae CONTIG439 GTC ORF with score 727 to: (ai:7501761442) (or:Klebsiella pneumoniae) 32203875_f2_107 399 16970 465 154 93 −3 mice|C57BL/6xCBA/ Q06666 (sr:, mouse) (de:octapeptide-repeat CaJ hybrid protein t2) 26377143_f2_114 400 16971 1011 336 120 −4 Escherichia coli S18537 3379541_f2_115 401 16972 486 161 133 −9 Enterobacter cloacae CONTIG410 GTC ORF with score 133 to: (ai:7000757953) (or:Pseudomonas aeruginosa) 35829541_f2_116 402 16973 633 210 224 −19 Enterobacter cloacae CONTIG410 GTC ORF with score 224 to: (ai:7000757954) (or:Pseudomonas aeruginosa) 12632067_f2_121 403 16974 462 153 196 −16 Klebsiella Contig525A GTC ORF with score 275 to: pneumoniae (ai:7000775494) (or:Pseudomonas aeruginosa) 6036628_f2_124 404 16975 972 323 198 −15 Enterobacter cloacae CONTIG481 GTC ORF with score 520 to: (ai:7501762729) (or:Klebsiella pneumoniae) 9859718_f3_130 405 16976 2001 666 2910 −9999 Pseudomonas P24563 (de:hypothetical 57.4 kd protein in aeruginosa pilt region (orf4)) 31273328_f3_132 406 16977 684 227 250 −20 Pseudomonas P24563 (de:hypothetical 57.4 kd protein in aeruginosa pilt region (orf4)) 15728966_f3_139 407 16978 732 243 151 −11 Klebsiella Contig332A GTC ORF with score 151 to: pneumoniae (ai:7000757977) (or:Pseudomonas aeruginosa) 12277036_f3_140 408 16979 1392 463 1112 −113 Stenotrophomonas AF031709 (de:stenotrophomonas maltophilia maltophilia cystathionine gamma-lyase-like protein(cys1) gene, complete cds.) 32683318_f3_152 409 16980 1326 441 550 −53 Klebsiella Contig526A GTC ORF with score 825 to: pneumoniae (ai:7000844364) (or:Enterobacter cloacae) 31256290_f3_153 410 16981 390 129 611 −59 Pseudomonas P43501 (de:pilh protein) aeruginosa 31289537_f3_165 411 16982 513 170 95 −4 Aspergillus Contig8078 GTC ORF with score 219 to: fumigatus (ai:175260) (or:Volvox carteri) 35797680_f3_174 412 16983 1155 384 1806 −186 Pseudomonas U79580 (de:pseudomonas aeruginosa pilk aeruginosa gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:cheb homolog) 11042255_f3_176 413 16984 1656 551 1067 −108 Pseudomonas U79580 (de:pseudomonas aeruginosa pilk aeruginosa gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:similar to xyls/arac protein family) 34636380_f3_180 414 16985 1089 362 121 −5 Enterobacter cloacae CONTIG508 GTC ORF with score 460 to: (ai:7501774708) (or:Klebsiella pneumoniae) 35707307_f3_185 415 16986 1254 417 14179055_13_189 416 16987 603 200 770 −76 Escherichia coli P37904 (de:18.7 kd protein in htrb-dini intergenic region precursor) 10550950_f3_191 417 16988 1362 453 1890 −195 Pseudomonas P52477 (de:multidrug resistance protein mexa aeruginosa precursor) 1074055_f3_192 418 16989 3156 1051 5248 −9999 Pseudomonas P52002 (de:multidrug resistance protein mexb aeruginosa (multidrug-efflux transporter mexb)) 12988966_f3_194 419 16990 1038 345 181 −10 Homo sapiens Z74615 (sr:human) (de:h. sapiens mrna for prepro-alpha1(i) collagen.) 261393_f3_195 420 16991 1473 490 284 −23 Klebsiella Contig525A GTC ORF with score 1123 to: pneumoniae (ai:7000829218) (or:Enterobacter cloacae) 33863875_c1_208 421 16992 1488 495 686 −67 Escherichia coli P25888 (de:putative atp-dependent ma helicase rhle) 25910937_c1_210 422 16993 1557 518 282 −24 Klebsiella Contig558A GTC ORF with score 282 to: pneumoniae (ai:7000758048) (or:Pseudomonas aeruginosa) 3395753_c1_219 423 16994 1569 522 16535207_c1_229 424 16995 489 162 134 −8 Caenorhabditis P34391 (de:putative cuticle collagen f09g8.6) elegans 24083256_c1_232 425 16996 552 183 151 −9 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm 160) mrna, complete cds.) (nt:160 kda) 11212705_c1_235 426 16997 531 176 119 −8 Acinetobacter CONTIG220 GTC ORF with score 119 to: baumannii C (ai:7000758073) (or:Pseudomonas aeruginosa) 5354791_c1_236 427 16998 984 327 161 −8 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain (type 6/strain uganda-1102) ie2hom mrna, complete Uganda-1102) cds.) (nt:similar to the immediate-early 2 protein of human) 34064092_c1_237 428 16999 414 137 116 −6 no gb taxonomy P28284 (sr:type 2/hg52,) (de:trans-acting match transcriptional protein icp0 (vmw 118 protein)) 33676092_c1_238 429 17000 537 178 143 −8 Saccharomyces X89715 (sr:baker's yeast) (de:s. cerevisiae cerevisiae aob567, aof1001, aoe110, aoe264 and aoe130 genes.) 10283415_c1_240 430 17001 837 278 151 −8 Dictyostelium P14328 (sr:, slime mold) (de:spore coat discoideum protein sp96) 7072716_c1_241 431 17002 981 326 282 −23 Saccharomyces X89715 (sr:baker's yeast) (de:s. cerevisiae cerevisiae aob567, aof1001, aoe110, aoe264 and aoe130 genes.) 1307341_c1_247 432 17003 705 234 127 −8 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 21563886_c1_256 433 17004 1524 507 145 −7 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′ region of gyra and gyrb (orf 3) 36120791_c1_257 434 17005 618 205 399 −37 Escherichia coli P52049 (de:hypotheiical 20.7 kd protein in gshb-ansb intergenic region (o211)) 21978293_c1_259 435 17006 2181 726 754 −75 Pseudomonas L19649 (fn:unknown) (sr:pseudomonas aeruginosa aeruginosa (strain pao) dna) (de:pseudomonas aeruginosa aspartate transcarbamoylase (pyrb) and dihydroorotase-like (pyrx) genes, complete cds's.) (nt:dihydroorotase- like 1305416_c1_261 436 17007 519 172 104 −3 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase-binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein:) 32511656_c1_264 437 17008 1413 470 589 −57 Klebsiella Contig332A GTC ORF with score 589 to: pneumoniae (ai:7000758102) (or:Pseudomonas aeruginosa) 12632162_c1_265 438 17009 1068 355 192 −15 Enterobacter cloacae CONTIG508 GTC ORF with score 257 to: (ai:7000758105) (or:Pseudomonas aeruginosa) 20051938_c1_267 439 17010 768 255 257 −22 Enterobacter cloacae CONTIG508 GTC ORF with score 257 to: (ai:7000758105) (or:Pseudomonas aeruginosa) 31773288_c1_269 440 17011 1419 472 1321 −135 Pseudomonas JQ0418 (ec:1.5.1.2) aeruginosa 31739416_c2_275 441 17012 357 118 100 −4 Beta vulgaris S51939 (sr:, beet) (ec:3.2.1.14) 14708291_c2_276 442 17013 1278 425 567 −55 Escherichia coli P25888 (de:putative atp-dependent rna helicase rhle) 33636705_c2_280 443 17014 2862 953 99 −1 southeastern Asian U70657 (sr:southeastern asian house mouse) house mouse (de:mus musculus castaneus sex determining protein (sry) gene, completccds.) (nt:hmg box transcription factor) 15644805_c2_282 444 17015 1251 416 212 −17 Klebsiella Contig425A GTC ORF with score 278 to: pneumoniae (ai:7000819900) (or:Enterobacter cloacae) 33985693_c2_284 445 17016 669 222 185 −15 Enterobacter cloacae CONTIG358 GTC ORF with score 185 to: (ai:7000758122) (or:Pseudomonas aeruginosa) 36033512_c2_292 446 17017 1077 358 537 −52 Escherichia coli A65080 31722635_c2_293 447 17018 1101 366 186 −12 Epstein-Barr virus M17294 (sr:human herpesvirus 4 (clone: h6) dna) (de:epstein-barr virus bamhi-h (bhlfl) region encoding an orf, partialcds.) (nt:orf; putative) 32438537_c2_294 448 17019 417 138 137 −8 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 33864656_c2_295 449 17020 294 97 91 −4 Aspergillus Contig5344 GTC ORF with score 103 to: fumigatus (ai:120246) (or:Mycoplasma pneumoniae) (de:mycoplasma pneumoniae section 38 of 63 of the complete genome.) (nt:similar to genbank accession number 138997 6, from) 16932306_c2_300 450 17021 537 178 119 −5 Pseudomonas putida X80272 (de:p. putida pprb gene.) 16526583_c2_307 451 17022 252 83 113 −6 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain= elegans bristol n2) (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 12626080_c2_310 452 17023 489 162 190 −14 Volvox carteri S22697 36033262_c2_311 453 17024 465 154 132 −8 Homo sapiens U89278 (fn:interacts with the vertebrate polycomb-group) (sr:human) (de:human polyhomeotic 2 homology (hph2) mrna, complete cds.) 36072933_c2_315 454 17025 363 120 105 −4 Caenorhabditis Z78418 (de:caenorhabditis elegans cosmid elegans f25d7, complete sequence.) (nt:similar to claustrin like: cdna cst ccmsh64f comes) 10001942_c2_319 455 17026 555 184 104 −3 Homo sapiens S65954 (sr:, man) 32282161_c2_321 456 17027 1107 368 1048 −106 Escherichia coli P04425 (ec:6.3.2.3) (de:synthetase) (gsh-s) (gshase)) 4877332_c2_326 457 17028 1095 364 1666 −171 Pseudomonas Q59653 (ec:2.1.3.2) (de:transcarbamylase) aeruginosa (atcase)) 9901031_c2_327 458 17029 891 296 1354 −138 Pseudomonas L19649 (fn:unknown) (sr:pseudomonas aeruginosa aeruginosa (strain pao) dna) (de:pseudomonas aeruginosa aspartate transcarbamoylase (pyrb) and dihydroorotase-like (pyrx) genes, complete cds's.) (nt:dihydroorotase-like 15838330_c2_329 459 17030 1434 477 499 −48 Klebsiella Contig332A GTC ORF with score 499 to: pneumoniae (ai:7000758167) (or:Pseudomonas aeruginosa) 35681966_c2_334 460 17031 309 102 173 −13 Pseudomonas P24564 (de:hypothetical 19.5 kd protein in aeruginosa pilt region (orf6)) 16225152_c2_336 461 17032 654 217 896 −90 Pseudomonas P24564 (de:hypothetical 19.5 kd protein in aeruginosa pilt region orf6)) 30208402_c2_338 462 17033 1059 352 1157 −117 Pseudomonas P24562 (de:hypothctical 24.5 kd protein in aeruginosa pilt 5′ region orf5)) 10641330_c2_339 463 17034 231 76 112 −6 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 5350961_c3_341 464 17035 603 200 154 −10 Aquifex acolicus A70373 14539205_c3_342 465 17036 900 299 602 −58 Aquifex acolicus D70424 32130160_c3_343 466 17037 1140 379 6520431_c3_348 467 17038 636 211 174 −13 Drosophila erecta P13730 (sr:, fruit fly) (de:salivary glue protein sgs-3 precursor 31377258_c3_349 468 17039 483 160 150 −9 Gallus gallus M25984 (sr:gallus gallus dna) (de:chicken alpha-2 domesticus collagen gene type i gene, exon 52.) 13958412_c3_351 469 17040 483 160 333 −30 Klebsiella Contig545A GTC ORF with score 333 to: pneumoniae (ai:7000758189) (or:Pseudomonas aeruginosa) 21976701_c3_352 470 17041 636 211 295 −26 Enterobacter cloacae CONTIG438 GTC ORF with score 295 to: (ai:7000758190) (or:Pseudomonas aeruginosa) 7129027_c3_353 471 17042 426 141 531 −51 Enterobacter cloacae CONTIG314 GTC ORF with score 531 to: (ai:7000758191) (or:Pseudomonas aeruginosa) 14300901_c3_356 472 17043 477 158 97 −3 Klebsiella Contig171A GTC ORF with score 726 to: pneumoniae (ai:7000824242) (or:Enterobacter cloacae) 12926582_c3_357 473 17044 246 81 109 −7 Klebsiella Contig262A GTC ORF with score 159 to: pneumoniae (ai:7000804762) (or:Pseudomonas aeruginosa) 16879378_c3_359 474 17045 462 153 757 −75 Pseudomonas P52003 (de:multidrug resistance operon repressor) aeruginosa 14714657_c3_362 475 17046 435 144 104 −4 Pleuronectes U39735 (de:pleuronectes americanus sperm americanus chromatin protein hmrbnp-1 mrna, partial cds.) (nt:hmrbnp-1; crosslinks nucleosomes in sperm) 5181258_c3_363 476 17047 1434 477 1268 −129 Bacillus sphaericus P22805 (cc:2.6.1.62) (de:aminotransferase)) 12994457_c3_364 477 17048 447 148 117 −7 Homo sapiens S53363 (sr:, man) (mp:11p15.5-11p15.5) 30730016_c3_365 478 17049 1491 496 11223392_c3_367 479 17050 492 163 110 −4 Dictyostelium P14328 (sr:, slime mold) (de:spore coat protein sp96) discoideum 34480056_c3_372 480 17051 948 315 115 −4 Enterobacter cloacae CONTIG456 GTC ORF with score 239 to: (ai:7000801274) (or:Pseudomonas aeruginosa) 32595161_c3_373 481 17052 7419 2472 100 −1 Drosophila U65431 (sr:fruit fly) (de:drosophila melanogaster melanogaster collagen type iv alpha 2 (dmcola2) mrna, complete cds.) (nt:d.m. collagen typc iv alpha 2) 6379806_c3_374 482 17053 2208 735 155 −8 Enterobacter cloacae CONTIG490 GTC ORF with score 300 to: (ai:7000797020) (or:Pseudomonas aeruginosa) 12984382_c3_378 483 17054 2001 666 367 −33 Escherichia coli U28377 (de:escherichia coli k-12 genome; approximately 65 to 68 minutes.) (nt:orf_o180; was also orf_o62p before splice) 16540906_c3_379 484 17055 624 207 316 −28 Thermus Y09536 (de:t. aquaticus pyrr, pyrb, bbc and pyrc genes.) thermophilus/T. aqua ticus/T. flavus 14722958_c3_380 485 17056 570 189 94 −2 Gallus gallus S53710 (cl:unassigned ribonucleoprotein domesticus repeat-containing proteins: ribonucleoprotein repeat homology) (sr:, chicken) 17072781_c3_381 486 17057 564 187 131 −7 Klebsiella Contig332A GTC ORF with score 499 to: pneumoniae (ai:7000758167) (or:Pseudomonas aeruginosa) 1406412_c3_386 487 17058 1563 520 970 −97 Ralstonia eutropha P13512 (de:cation efflux system protein czcd) 10275958_c3_390 488 17059 633 210 141 −7 Micrococcus luteus JQ0405 11914682_f1_5 489 17060 438 145 299 −26 Haemophilus P44886 (de:hypothetical protein hi0827 precursor) influenzae 32245207_f1_6 490 17061 1758 585 662 −65 Klebsiella Contig536A GTC ORF with score 662 to: pneumoniae (ai:7000758235) (or:Pseudomonas aeruginosa) 32527036_f1_7 491 17062 2313 770 159 −10 Azospirillum X70360 (de:a. brasilense carr gene.) brasilense 10260206_f1_9 492 17063 339 112 108 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16660216_f1_11 493 17064 2181 726 282 −24 Enterobacter cloacae CONTIG431 GTC ORF with score 117 to: (ai:99504) (or: Mus musculus domesticus) cl: unassigned hmg box proteins: hmg box homology) (sr:, western european house mouse) (mp:y) 12891340_f1_14 494 17065 1638 545 1424 −146 Streptomyces AL031184 (de: streptomyces coelicolor cosmid coelicolor 2a11.) (nt: sc2a11.03c, sdaa, probable 1-serine dehydratase.) 12611068_f1_16 495 17066 1116 371 621 −60 Pseudomonas AF012537 (de:pseudomonas aeruginosa aeruginosa acetyl-coa synthetase gene, partial cds, andarginine and ornithine binding protein (aotj), membrane protein (aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), and argr (argr) genes, complete cds.) (. . . 26760443_f1_20 496 17067 1299 432 201 −12 Micrococcus luteus JQ0405 13151387_f1_21 497 17068 420 139 150 −10 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 24658262_f1_22 498 17069 915 304 97 −2 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 30339792_f1_26 499 17070 1620 539 16284705_f1_28 500 17071 528 175 93 −2 Pseudomonas S29309 aeruginosa 12598790_f1_31 501 17072 672 223 159 −10 Burkholderia U41162 (sr:burkholderia cepacia cepacia strain=17616) (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 33337705_f1_33 502 17073 2100 699 22906291_f1_35 503 17074 1095 364 294 −26 Pyrococcus AP000004 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna) (de:pyrococcus horikoshii ot3 genomic dna, 777001-994000 nt. position (4.7).) (nt:similar to:Imrpongen percent ident: 37.019) 22010151_f1_36 504 17075 657 218 34198533_f1_37 505 17076 2049 682 626 −61 Archacoglobus G69306 fulgidus 3251041_f1_38 506 17077 2100 699 632 −62 Bacillus P45866 (de:hypothetical 79.2 kd protein in subtilis/Bacillus acda 5′ region) globigii 12125841_f1_39 507 17078 816 271 183 −12 Pseudomonas Z54213 (de:p. aeruginosa algy gene.) aeruginosa 31429758_f1_41 508 17079 516 171 109 −4 Orf virus B34768 20391463_f1_45 509 17080 228 75 218 −18 Bacillus C69931 subtilis/Bacillus globigii 14583537_f1_47 510 17081 411 136 144 −10 Bos primigenius A39762 (cl:collagen alpha 1(xiv) taurus chain:fibronectin type iii repeat homology:von willebrand factor type a repeat homology) (sr:, cattle) 31915916_f1_48 511 17082 294 97 33712530_f1_49 512 17083 894 297 114 −3 no gb taxonomy U52064 (de:kaposi's sarcoma-associated match herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 16900817_f1_58 513 17084 522 173 149 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 36062662_fI _60 514 17085 924 307 137 −6 Streptomyces Z46913 (de:s. ambofaciens gene for ambofaciens hypothetical polyketide gene.) (nt:putative) 31505287_f1_61 515 17086 513 170 113 −5 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain= elegans bristol n2) (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 13101592_f2_66 516 17087 1275 424 445 −42 Klebsiella Contig451A GTC ORF with score 445 to: pneumoniae (ai:7000758295) (or:Pseudomonas aeruginosa) 3239706_f2_71 517 17088 444 147 469 −45 Enterobacter cloacae CONTIG459 GTC ORF with score 173 to: (ai:212910) (or:Azospirillum brasilense) (de:a. brasilense carr gene.) (nt:orf2) 3019812_f2_74 518 17089 1662 553 36456955_f2_76 519 17090 1206 401 133 −8 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna, cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. nosition (6/7).) 15085218_f2_89 520 17091 1182 393 929 −93 Escherichia coli P33019 (de:hypothetical 36.9 kd protein in lysp-nfo intergenic region) 30199066_f2_93 521 17092 3177 1058 561 −53 Pseudomonas AF012537 (de:pseudomonas aeruginosa acetyl-coa aeruginosa synthetase gene, partial cds; and arginine and ornithine binding protein (aotj), membrane protein (aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), and argr (argr) genes, complete cds.) (. . . 25522558_f2_98 522 17093 1434 477 7244203_f2_102 523 17094 678 225 490 −47 Streptomyces AF072709 (de:streptomyces lividans amplifiable lividans element aud4: putativetranscriptional regulator, putative ferredoxin, putative cytochrome450 oxidoreductase, and putative oxidoreductase genes, completecds; and unknown genes.) (nt:orf1; hypothe . . . 16253843_f2_105 524 17095 411 136 114 −5 Saccharomyces P08640 (sr:, baker's yeast) (cc:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 11957292_f2_106 525 17096 336 111 110 −5 Sus scrofa domestica I47141 (sr:, domestic pig) 10819580_f2_107 526 17097 1062 353 335 −29 Thermoanaerobacter S35706 brockii 22370206_f2_114 527 17098 2067 688 34119692_f2_117 528 17099 540 179 11886080_f2_118 529 17100 576 191 31659381_f2_121 530 17101 1341 446 30267558_f2_122 531 17102 1983 660 105 −3 Aspergillus Contig8591 GTC ORF with score 247 to: fumigatus (ai:405746) (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator { clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 16275091_f2_124 532 17103 831 276 92 −1 Dictyostelium AJ224893 (fn:spore differentiation) discoidcum (de:dictyostelium discoideum srfa gene. 3160408_f3_138 533 17104 1641 546 1221 −124 Escherichia coli P17447 (de:high-affinity choline transport protein) 31535332_f3_143 534 17105 1695 564 15750841_f3_144 535 17106 1146 381 125 −4 mice|C57BL/6xCBA/ U76716 (sr:house mouse) (de:mus musculus CaJ hybrid voltage-sensitive calcium channel alpha 1 a (ccha1a) mrna, complete cds.) (nt:ion channel) 25488876_f3_146 536 17107 1518 505 2353968_f3_147 537 17108 1056 351 143 −9 Klebsiella Contig523A GTC ORF with score 206 to: pneumoniae (ai:7000796429) (or:Pseudomonas aeruginosa) 36069557_f3_152 538 17109 1623 540 12973202_f3_153 539 17110 720 239 96 −2 equine herpesvirus P28968 (sr:ab4p,chv-1) (de:glycoprotein x type 1 EVH-1 precursor) 16611466_f3_158 540 17111 972 323 197 −16 Klebsiella Contig441A GTC ORF with score 536 to: pneumoniae (ai:7000835893) (or:Enterobacter cloacae) 36066391_f3_174 541 17112 1968 655 90 −2 Klebsiella Contig346A Klebsiella pneumoniae, GTC, pneumoniae rel 1.0, 9812146 32620916_f1_175 542 17113 1002 333 200 −14 Schizosaccharomyce P78790 (sr:, fission yeast) (de:(alpha-etf)) s pombe 11895750_f3_177 543 17114 609 202 16661415_f3_179 544 17115 564 187 120 −5 Caenorhahditis Z78418 (de:caenorhabditis elegans elegans cosmid f25d7, complete sequence.) (nt:similar to claustrin like; cdna est ccmsh64f comes) 29927206_f3_180 545 17116 705 234 133 −6 Homo sapiens X87248 (sr:human) (de:h. sapiens mrna for hp8 protein.) 10808332_f3_182 546 17117 462 153 101 −3 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early pseudorabies virus protein ie175 PRV 22161577_f3_186 547 17118 1176 391 333 −30 Mycobacterium Z92774 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 150/162.) (nt:rv3571, (mtcy06g11.18), len: 358. electron) 33704590_f3_188 548 17119 663 220 99 −2 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 15121018_c1_202 549 17120 615 204 166 −12 Mycobacterium Z95554 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 72/162.) (nt:rv1624c, (mtcy01b2.16c), len: 195. function:) 31808406_c1_210 550 17121 540 179 112 −4 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ic-b) 2853792_c1_212 551 17122 1908 635 1286532_c1_214 552 17123 669 222 105 −6 Enterococcus CONTIG707 GTC ORF with score 107 to: faccalis (ai:7500720569) (or:Clostridium acetobutylicum) 6433286_c1_215 553 17124 2871 956 154 −8 Aspergillus Contig8948 GTC ORF with score 249 to: fumigatus (ai:7000782680) (or:Pseudomonas aeruginosa) 15052158_c1_216 554 17125 1740 579 1735 −179 Pseudomonas putida P31048 (de:hypothetical 54.3 kd protein in lpd-3 5′ region (orf2)) 10800331_c1_219 555 17126 789 262 154 −8 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene, complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 10260406_c1_222 556 17127 1320 439 10272555_c1_227 557 17128 384 127 111 −5 Chlamydomonas S50755 reinhardtii strain UTEX 1061 31423966_c1_229 558 17129 927 308 123 −7 Enterobacter cloacae CONTIG509 GTC ORF with score 123 to: (ai:7000758458) (or:Pseudomonas aeruginosa) 31644791_c1_230 559 17130 525 174 103 −6 Treponema pallidum AE001200 (de:treponema pallidum section 16 of 87 of the complete genome.) (nt:similar to gb:142023 sp:p44679 pid:1003656) 34511283_c1_232 560 17131 1038 345 240 −20 Klebsiella Contig523A GTC ORF with score 518 to: pneumoniae (ai:7000817451) (or:Enterobacter cloacae) 12392028_c1_235 561 17132 1053 350 122 −5 Brassica napus Y08986 (sr:rape) (de:b. napus gene encoding oleosin-like protein.) 15113455_c1_236 562 17133 1401 466 14978466_c1_237 563 17134 1659 552 605 −59 Klebsiella Contig496A GTC ORF with score 897 to: pneumoniae (ai:7000824038) (or:Enterobacter cloacae) 5097840_c1_240 564 17135 852 283 598 −58 Bacillus P46921 (de:glycine betaine transport system subtilis/Bacillus permease protein opuab) globigii 15744033_c1_241 565 17136 1182 393 716 −71 Salmonella P17328 (de:glycine betaine/l-proline transport atp- choleraesuis binding protein prov) serotype typhimurium 7120766_c1_246 566 17137 639 212 556 −54 Escherichia coli P17446 (de:regulatoty protein beti) 12695818_c1_247 567 17138 1533 510 1978 −204 Escherichia coli S15181 (cl:aldehyde dehydrogenase (nad+): aldehyde dehydrogenase homology) (cc:1.2.1.8) (mp:7.5 min) 11192931_c1_248 568 17139 1794 597 2433 −253 Escherichia coli P17444 (ec:1.1.99.1) (de:choline dehydrogenase, (chd)) 16930456_c2_259 569 17140 1608 535 25891068_c2_261 570 17141 1458 485 16219592_c2_262 571 17142 189 62 32672956_c2_269 572 17143 1209 402 101 −4 Chrysemys picta A58208 (cl:sperm histone) (sr:, painted turtle) 5212535_c2_275 573 17144 282 93 109 −7 Enterobacter cloacae CONTIG464 GTC ORF with score 109 to: (ai:7000758504) or:Pseudomonas aeruginosa) 33839405_c2_281 574 17145 219 72 99 −5 Schizophyllum AF005405 (fn:oxidation of the 5′-hydroxymethyl commune of) (de:schizophyllum commune b2-aldehyde-forming enzyme mrna, completecds.) (nt:secreted enzyme) 35789182_c2_285 575 17146 699 232 103 −3 Aspergillus Contig9071 GTC ORF with score 103 to: fumigatus (ai:7000758514) or:Pseudomonas aeruginosa) 34269756_c2_287 576 17147 825 274 150 −10 Homo sapiens P52758 (sr:, human) (de:homology)) 32552318_c2_288 577 17148 1899 632 586 −57 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene, complete cds; and unknown gene.) (nt:arginine biosynthetic protein; arge) 33720808_c2_291 578 17149 1353 450 21735767_c2_292 579 17150 1890 629 533 −51 Archaeoglobus E69400 fulgidus 31879205_c2_293 580 17151 663 220 137 −7 Plasmodium P08675 (sr:london,) (de:circumsporozoite cynomolgi protein precursor (cs)) 32511255_c2_294 581 17152 549 182 123 −8 Aspergillus Contig9654 GTC ORF with score 123 to: fumigatus (ai:7000758523) (or:Pseudomonas aeruginosa) 24422677_c2_295 582 17153 921 306 684 −67 Escherichia coli P32484 (de:hypothetical transcriptional regulator in lysp-nfo intergenic region 261278_c2_296 583 17154 654 217 103 −2 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 7125308_c2_301 584 17155 435 144 142 −10 Clostridium Contig192H GTC ORF with score 205 to: acetobutylicum (ai:4500689127) (or:Enterococcus faccalis) 10167793_c2_303 585 17156 402 133 121 −8 Enterobacter cloacae CONTIG456 GTC ORF with score 146 to: (ai:7000780481) (or:Pseudomonas aeruginosa) 15838458_c2_305 586 17157 1071 356 266 −23 Lyme disease H70117 (sr:, lyme disease spirochete) spirochete 10291040_c2_306 587 17158 750 249 112 −4 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35754766_c2_307 588 17159 1428 475 317 −28 Enterobacter cloacae CONTIG459 GTC ORF with score 533 to: (ai:7501748159) (or:Klebsiella pneumoniae) 29808406_c2_311 589 17160 570 189 107 −4 Homo sapiens A48018 (sr:, man) (mp:4q13−4q21) 10675958_c2_313 590 17161 534 177 163 −11 Borcogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10726692_c2_315 591 17162 570 189 205 −17 Klebsiella Contig451A GTC ORF with score 205 to: pneumoniae (ai:7000758544) (or:Pseudomonas aeruginosa) 16800800_c3_318 592 17163 2478 825 21650811_c3_322 593 17164 1350 449 351 −32 Escherichia coli P76253 (ec:1.14.1.—) (de:putative dioxygenase alpha subunit yeaw,) 7161407_c3_331 594 17165 1245 414 32110068_c3_332 595 17166 456 151 112 −5 Homo sapiens X63071 (sr:human) (de:h. sapiens mrna for novel dna binding protein.) 34620793_c3_333 596 17167 1779 592 120 −4 Streptomyces AL022268 (de:streptomyces coelicolor cosmid coelicolor 4h2.) (nt:sc4h2.20, probable aminotransferase, len: 532); 31489441_c3_338 597 17168 771 256 354 −33 Klebsiella Contig498A GTC ORF with score 354 to: pneumoniae (ai:7000758567) (or:Pseudomonas aeruginosa) 21961391_c3_339 598 17169 660 219 124 −5 Homo sapiens Y13247 (sr:human) (de:homo sapiens fb19 mrna.) 13791681_c3_341 599 17170 1458 485 683 −67 Cyanobacterium S77027 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803,) syncchocystis 14963275_c3_343 600 17171 711 236 7235411_c3_348 601 17172 852 283 116 −7 Enterobacter cloacae CONTIG436 GTC ORF with score 325 to: (ai:7501791606) (or:Klebsiella pneumoniae) 36535831_c3_349 602 17173 957 318 225 −19 Lyme disease H70117 (sr:, lyme disease spirochete) spirochete 4007281_c3_350 603 17174 957 318 317 −42 Mycobacterium Z81360 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 78/162.) (nt:rv1718, (mtcy04c12.03), len: 272. similar to) 11812625_c3_351 604 17175 342 113 119 −6 Streptomyces L20249 (sr:streptomyces coriofaciens (library: coriofaciens isp 5485) dna) (de:streptomyces coriofaciens beta-ketoacyl synthase homologue gene, partial cds.) (nt:homologous to saccharopolyspora erythraea) 36226643_c3_354 605 17176 1245 414 430 −40 Mycobacterium Z80108 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 62/162.) (nt:rv 1400c, (mtcy21b4.17c), len: 320. possible) 22161711_c3_355 606 17177 423 140 192 −15 Klebsiella Contig523A GTC ORF with score 97 to: pneumoniae (ai:73282) (or:Dictyostelium discoideum) (sr:,slime mold) (de:g-box binding factor (gbf)) 6738336_c3_356 607 17178 606 201 109 −3 African clawed frog U85970 (sr:african clawed frog) (de:xenopus laevis middle molecular weight neurofilament proteinnf-m(2) mrna, complete cds.) (nt:neuronal intermediate filament protein; duplicated) 32667580_c3_358 608 17179 912 303 114 −4 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 11851430_c3_367 609 17180 2196 731 96 −1 Mycobacterium AL009198 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 144/162.) (nt:rv3370c, (mtv004.28c), len: 1079, dnae, probable) 23628207_c3_371 610 17181 1932 643 133 −8 Pseudomonas U54795 (de:pseudomonas aeruginosa aeruginosa betaine semialdehyde dehydrogenase (betb) gene, partial cds.) 32305191 _c3_372 611 17182 333 110 231 −19 Klebsiella Contig536A GTC ORF with score 231 to: pneumoniae (ai:7000758601) (or:Pseudomonas aeruginosa) 32707256_c3_375 612 17183 543 180 184 −14 Enterobacter cloacae CONTIG459 GTC ORF with score 184 to: (ai:7000758604) (or:Pseudomonas aeruginosa) 11723913_c3_376 613 17184 396 131 222 −19 Enterobacter cloacae CONTIG459 GTC ORF with score 222 to: (ai:7000758605) (or:Pseudomonas aeruginosa) 26360957_c3_377 614 17185 1341 446 592 −59 Rickettsia AJ235269 Rickettsia prowazekii strain prowazekii Madrid E, complete genome. 32620840_f1_1 615 17186 1278 425 239 −20 Klebsiella Contig551A GTC ORF with score 239 to: pneumoniae (ai:7000758607) (or:Pseudomonas aeruginosa) 23521883_f1_5 616 17187 1728 575 111 −4 Klebsiella Contig549A GTC ORF with score 124 to: pneumoniae (ai:405746) (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator (clone t2, repetitive sequence) (mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author) 16491467_f1_8 617 17188 849 282 646 −63 Mycobacterium AL021958 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 35/162.) (nt:rv0753c, (mtv04l.27c), len: 510. mmsa, probable) 14534842_f1_9 618 17189 519 172 433 −41 Escherichia coli P25527 (de:permease)) 7225330_f1_16 619 17190 345 114 118 −7 Rhizobium sp. P55533 (sr:ngr234,) (de:hypothetical 9.2 kd protein y4ko) 2551651_f1_17 620 17191 366 121 672 −66 Enterococcus CONTIG108 GTC ORF with score 672 to: faecalis (ai:7000758623) (or:Pseudomonas aeruginosa) 35682333_f1_20 621 17192 573 190 145 −10 mice|C57BL/6xCBA/ D29149 (cl:proline-rich protein) (sr:, house CaJ hybrid mouse) 33830291_f1_22 622 17193 741 246 100 −2 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 4035436_f1_25 623 17194 1488 495 33675913_f1_27 624 17195 582 193 429 −40 Escherichia coli P52077 (de:elaa protein) 26052206_fI_30 625 17196 1584 527 121 −3 Molluscum L10127 (sr:molluscum contagiosum virus contagiosum virus type 1 dna) (de:molluscum subtype 1 contagiosum virus type 1 orf1 and orf2 dna.) (nt:orf17) 16276081_f1_42 626 17197 702 233 36134828_f1_47 627 17198 1500 499 13927281 _f1_63 628 17199 486 161 136 −9 Achromobacter A61183 georgiopolitanum 32166380_f1_65 629 17200 420 139 103 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35604030_f1_69 630 17201 1356 451 151 −7 Escherichia coli D90774 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 10817661_f1_86 631 17202 1677 558 225 −18 Orgyia O10341 (sr:,opmnpv) (de:hypothetical 29.3 kd pseudotsugata protein (or(92)) multinuclcocapsid nuclear polyhedrosis virus OpMNPV 12620317_f1_87 632 17203 456 151 133 −8 Sus scrofa domestica I47141 (sr:, domestic pig) 16925681_f1_92 633 17204 354 117 177 −13 Aquifex aeolicus F70386 16541290_f1_96 634 17205 456 151 138 −8 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b) 16995656_f1_99 635 17206 1626 541 161 −8 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′ region of gyra and gyrb (orf 3)) 34192942_f2_101 636 17207 1404 467 1134 −115 Escherichia coli P76641 (de:hypothetical 50.2 kd protein in kdui-lyss intergenic region) 11848405_f2_104 637 17208 1407 468 1862 −192 Pseudomonas putida A42800 (cl:beta-alanine--pyruvate transaminase) (ec:2.6.1.18) 16510305_f2_105 638 17209 900 299 160 −12 Klebsiella Contig471A GTC ORF with score 160 to: pneumoniae (ai:7000758711) (or:Pseudomonas aeruginosa) 26567030_f2_109 639 17210 255 84 14195840_f2_110 640 17211 837 278 775 −77 Escherichia coli P25527 (de:permease)) 31817028_f2_111 641 17212 468 155 209 −17 Enterobacter cloacae CONTIG482 GTC ORF with score 209 to: (ai:7000758717) (or:Pseudomonas aeruginosa) 12971893_f2_112 642 17213 1314 437 33690625_f2_114 643 17214 948 315 427 −40 Escherichia coli P45691 (de:hypothetical transcriptional regulator in argr-cafa intergenic region) 32673291_f2_122 644 17215 702 233 131 −7 Klebsiella Contig551A GTC ORF with score 131 to: pneumoniae (ai:7000758728) (or:Pseudomonas aeruginosa) 33869583_f2_127 645 17216 1104 367 98 −2 Nocardioides Z93338 (de:a. simplex ksdi genes and three simplex open reading frames.) (nt:low similarity to phytoene dehydrogenase from) 10626887_f2_133 646 17217 1641 546 25886265_f2_135 647 17218 696 231 129 −5 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain (type 6/strain uganda-1102) ie2hom mrna, complete Uganda-1102) cds.) (nt:similar to the immediate-early 2 protein of human) 820833_f2_141 648 17219 435 144 101 −3 Dictyostelium P14328 (sr:, slime mold) (de:spore coat discoideum protein sp96) 35425755_f2_142 649 17220 558 185 92 −4 Klebsiella Contig517A GTC ORF with score 333 to: pneumoniae (ai:7000822737) (or:Enterobacter cloacae) 25798577_f2_150 650 17221 2367 788 314 −27 Enterobacter cloacae CONTIG370 GTC ORF with score 322 to: (ai:7000807782) (or:Pseudomonas aeruginosa) 32130263_f2_152 651 17222 837 278 199 −14 Microbacterium X79027 (de:m. ammoniaphilum genes ammoniaphilum mamir and mamim.) 35603251_f2_154 652 17223 387 128 133 −9 Enterobacter cloacae CONTIG222 GTC ORF with score 133 to: (ai:7000758760) (or:Pseudomonas aeruginosa) 16144708_f2_155 653 17224 540 179 101 −3 Enterobacter cloacae CONTIG370 GTC ORF with score 322 to: (ai:7000807782) (or:Pseudomonas aeruginosa) 16300201_f2_156 654 17225 1581 526 227 −18 Enterobacter cloacae CONTIG435 GTC ORF with score 227 to: (ai:7000758762) (or:Pseudomonas aeruginosa) 31339558_f2_158 655 17226 408 135 135 −8 Streptomyccs fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 30760205_f2_165 656 17227 630 209 117 −5 infectious bovine P30022 (sr:p8-2,) (de:tegument protein ul49 rhinotracheitis virus homolog) 35679206_f2_170 657 17228 621 206 163 −12 Enterobacter cloacae CONTIG436 GTC ORF with score 163 to: (ai:7000758776) (or:Pseudomonas aeruginosa) 21738816_f2_171 658 17229 2019 672 750 −74 Enterobacter cloacae CONTIG436 GTC ORF with score 750 to: (ai:7000758777) (or:Pseudomonas aeruginosa) 16897933_f2_172 659 17230 468 155 122 −6 Homo sapiens AB002322 (sr:homo sapiens male brain edna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 6142706_f2_178 660 17231 6885 2294 295 −21 Micrococcus luteus JQ0405 5101443_f2_179 661 17232 738 245 343 −32 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 2/162.) (nt:rv0018c, (mtcy 10h4. 18c), len: 514,highly similar to) 35336663_f2_180 662 17233 402 134 97 −4 migratory locust AJ000390 (sr:migratory locust) (de:locusta migratoria mrna for nachr alpha1 subunit.) 35286580_f3_183 663 17234 618 205 154 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 24110042_f3_187 664 17235 450 149 97 −2 Caenorhabditis Z75539 (de:caenorhabditis elegans cosmid elegans f28c1, complete sequence.) (nt:predicted using genefinder, cdna est embl:c 13354) 17070467_f3_188 665 17236 861 286 708 −71 Mycobacterium AL123456 (de:mycobacterium tubcrculosis tuberculosis h37rv complete genome; segment 35/162.) (nt:rv0753c, (mtv041.27c), len: 510. mmsa, probable) 12994215_f3_189 666 17237 723 240 129 −8 Klebsiella Contig471A GTC ORF with score 129 to: pneumoniae (ai:7000758795) (or:Pseudomonas aeruginosa) 2585191_f3_190 667 17238 564 187 112 −7 Klebsiella Contig493A GTC ORF with score 195 to: pneumoniae (ai:7000812226) (or:Pseudomonas aeruginosa) 12578816_f3_191 668 17239 468 155 176 −14 Acinetobacter CONTIG220 GTC ORF with score 176 to: baumannii C (ai:7000758797) (or:Pseudomonas aeruginosa) 31744043_f3_193 669 17240 1104 367 31922092_f3_194 670 17241 351 116 488532_f3_198 671 17242 459 152 123 −6 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ic-b) 3367207_f3_199 672 17243 2316 771 194 −12 malaria parasite X69926 (sr:malaria parasite) (de:p. falciparum (b3) hrpii gene, exon 2.) 29767706_f3_205 673 17244 543 180 126 −6 Acanthamoeba P10569 (sr:, amoeba) (de:myosin ic heavy castellanii chain) 6850791_f3_207 674 17245 714 237 121 −6 Enterobacter cloacae CONTIG430 GTC ORF with score 485 to: (ai:7000776269) (or:Pseudomonas aeruginosa) 32707076_f3_211 675 17246 456 151 33708542_f3_214 676 17247 1587 528 184 −10 Oryctolagus P16230 (sr:, rabbit) (de:precursor (hep)) cuniculus 22142255_f3_218 677 17248 1350 449 3322665_f3_221 678 17249 483 160 91 −3 Enterobacter cloacae CONTIG500 GTC ORF with score 107 to: (ai:7000723201) (or:no gb taxonomy match) (de:human papillomavirus type 80 e6, e7, e1, e2, e4, 12, and 11 genes.) (nt:putative) 31891467_f3_222 679 17250 1800 599 148 −6 equine herpesvirus AF030027 (fn:very large tegument protein) type 4 EHV-4 (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 7301083_f3_225 680 17251 672 223 106 −4 Gallus gallus K02113 (sr:chicken) (de:gallus gallus domesticus vitellogenin gene coding for phosvitin, exons 23 and 24.) 10438276_f3_230 681 17252 867 288 159 −9 Homo sapiens Z34277 (sr:human) (de:h. sapiens (jer47) muc5ac mrna for mucin (partial).) 24782151_f3_232 682 17253 468 155 31807905_f3_233 683 17254 1308 435 31910958_f3_237 684 17255 2955 984 603 −58 Enterobacter cloacae CONTIG435 GTC ORF with score 603 to: (ai:7000758843) (or:Pseudomonas aeruginosa) 11988266_f3_238 685 17256 444 147 146 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 34258293_f3_239 686 17257 2379 792 289 −25 Enterobacter cloacae CONTIG435 GTC ORF with score 289 to: (ai:7000758845) (or:Pseudomonas aeruginosa) 16277168_f3_242 687 17258 288 95 196 −16 Acinetobacter CONTIG187 GTC ORF with score 196 to: baumannii C (ai:7000758848) (or:Pseudomonas aeruginosa) 16037583_f3_246 688 17259 1266 421 15723886_f3_248 689 17260 1674 557 159 −8 Murine herpesvirus U97553 (de:murine herpesvirus 68 strain 68 wums, (complete genome.) 6925032_f3_249 690 17261 1350 449 337 −30 Vibrio cholerae AJ231091 (de:vibrio cholerae z29f gene.) 12932183_f3_250 691 17262 1131 376 641 −63 Enterobacter cloacae CONTIG436 GTC ORF with score 216 to: (ai:4000713594) (or:Vibrio alginolyticus) (sr:vibrio alginolyticus (strain:vi05) dna) (de:vibrio alginolyticus dna for poma, pomb, complete cds.) (nt:essential for rotation of the sodium-driven polar) 16898316_f3_251 692 17263 3756 1251 250 −17 Legionella Y15044 (de:legionella pneumophila 22kb dna pneumophila fragment from icm gene cluster.) 13026031_f3_254 693 17264 453 150 196 −14 Bacillus H69878 subtilis/Bacillus globigii 5989705_c1_269 694 17265 1605 534 155 −10 Aspergillus Contig8591 GTC ORF with score 247 to: fumigatus (ai:405746) (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence} (mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 12757691_c1_271 695 17266 747 248 147 −7 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 2598556_c1_281 696 17267 2499 832 144 −6 blue mussel AF015539 (sr:blue mussel) (de:mytilus edulis precollagen p (precol-p) mrna, complete cds.) 11930441_c1_283 697 17268 693 230 109 −6 longfin squid S56117 (sr:, longfin squid) 22744581_c1_284 698 17269 801 266 154 −9 Plasmodium vivax P08677 (de:circumsporozoite protein precursor (cs)) 16902205_c1_290 699 17270 411 136 127 −8 Drosophila P13238 (sr:, fruit fly) (de:sv23)) melanogaster 14960033_c1_297 700 17271 621 206 169 −12 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopcptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16847555_c1_301 701 17272 1206 401 32286291_c1_307 702 17273 1311 436 21769081_c1_308 703 17274 837 278 567 −55 Escherichia coli P17582 (ec:4.2.1.1) (de:carbonic anhydrase,) 20174207_c1_309 704 17275 1392 463 569 −57 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 141/162.) (nt:rv3273, (mtcy71.13), len: 764, membrane protein,) 480055_c1_314 705 17276 1359 452 138 −8 Glossus humanus AF008298 (sr:glossus humanus) (de:glossus humanus cytochrome c oxidase subunit i (coi) gene, mitochondrial gene encoding mitochondrial protein, partial cds.) 13776916_c1_315 706 17277 1086 361 190 −25 Paracoccus P06030 (ec:1.9.3.1) (de:subunit 3) denitrificans (oxidase aa(3) subunit 3)) 24072842_c1_318 707 17278 1179 392 150 −8 Aquifex acolicus D70314 33848780_c1_320 708 17279 504 167 275 −24 Pseudomonas P47206 (sr:, pseudomonas perfectomarina) stutzeri (de:hypothetical protein in apt 3′ region (fragment)) 2422650_c1_321 709 17280 642 213 240 −20 Klebsiella Contig302A GTC ORF with score 240 to: pneumoniae (ai:7000758927) (or:Pseudomonas aeruginosa) 2041301_c1_323 710 17281 780 259 275 −24 Rhizobium S72165 leguminosarum bv. viciae 32135155_c1_324 711 17282 612 203 299 −26 Rhizobium S72164 leguminosarum bv. viciae 36148506_c1_326 712 17283 1080 359 116 −7 Enterobacter cloacae CONTIG451 GTC ORF with score 181 to: (ai:7000767457) (or:Pseudomonas aeruginosa) 35725168_c1_329 713 17284 369 122 112 −6 Achromobacter A61183 georgiopolitanum 14707183_c1_340 714 17285 477 158 107 −4 infectious bovine Z78205 (de:bovine herpesvirus type 1 rhinotracheitis virus ul22-35 genes.) (nt:homolog of icp18.5 or hsv-1) 24417700_c1_341 715 17286 741 246 379 −35 Klebsiella Contig471A GTC ORF with score 379 to: pneumoniae (ai:7000758947) (or:Pseudomonas aeruginosa) 35345287_c1_344 716 17287 543 180 142 −9 Achromobacter A61183 georgiopolitanum 31276666_c1_346 717 17288 336 111 90 −5 Apergillus Contig9020 GTC ORF with score 126 to: fumigatus (ai:113583) (or:Saccharomyces cerevisiae) de:(yjr151c) (pn:hypothetical 118:similarity to mucin proteins, yk1224c, sta1p) (gn:j2223) (gtcfc:11.1) (ec:) (yj9p_yeast) (keggfc:11.2) (sgdfc:9.1.0) (db:gtc-saccharomyces cerevisiae)) 5901055—c2_351 718 17289 408 135 108 −5 Homo sapiens PN0099 (sr:, man) 31892191_c2_352 719 17290 3774 1257 376 −33 Enterobacter cloacae CONTIG436 GTC ORF with score 376 to: (ai:7000758958) (or:Pseudomonas aeruginosa) 16849041_c2_353 720 17291 3054 1017 219 −17 Enterobacter cloacae CONTIG436 GTC ORF with score 219 to: (ai:7000758959) (or:Pseudomonas aeruginosa) 5183326_c2_355 721 17292 816 271 229 −18 silkworm S74439 (sr:silkworm) (de:silk fibroin heavy chain {3′ region} (bombyx mori=silkworms, mrnapartial, 2008 nt).) (nt:this sequence comes from FIG. 1c.) 33853968_c2_357 722 17293 1074 357 471 −45 Enterobacter cloacae CONTIG436 GTC ORF with score 471 to: (ai:7000758963) (or:Pseudomonas aeruginosa) 16928291_c2_358 723 17294 681 226 120 −6 Klebsiella Contig217A GTC ORF with score 282 to: pneumoniae (ai:5500695239) (or:Alcelaphine herpesvirus 1) (sr:wildebeest herpesvirus) (de:alcelaphine herpesvirus 1 1-dna, complete sequence.) (nt:orf73; similar to h, saimiri and kshv orf73) 13067628_c2_359 724 17295 1485 494 343 −31 Enterobacter cloacae CONTIG436 GTC ORF with score 343 to: (ai:7000758965) (or:Pseudomonas aeruginosa) 36428877_c2_361 725 17296 882 293 385 −36 Enterobacter cloacae CONTIG435 GTC ORF with score 385 to: (ai:7000758967) (or:Pseudomonas aeruginosa) 14708511_c2_362 726 17297 2367 788 1353 −138 Enterobacter cloacae CONTIG435 GTC ORF with score 1353 to: (ai:7000758968) (or:Pseudomonas aeruginosa) 34635030_c2_365 727 17298 3150 1049 1418 −145 Cyanobacterium S76431 (cl:atp-dependent clp proteinase synechocystis chain a) (sr:pcc 6803,, pcc 6803) (sr:pcc 6803,) (ec:3.4.21.—) 32523556_c2_369 728 17299 1056 351 166 −9 Micrococcus luteus JQ0405 35367276_c2_372 729 17300 780 259 110 −3 Homo sapiens M77663 (sr:homo sapiens cdna to mrna) (de:human keratin 10 mrna, 3′ end.) 14345125_c2_373 730 17301 1863 620 165 −8 Homo sapiens Q07283 (sr:, human) (de:trichohyalin) 35414756_c2_374 731 17302 705 234 93 −4 Saccharomyces S66936 (rnp:15r) cerevisiae 36364466_c2_375 732 17303 522 173 125 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32696006_c2_377 733 17304 1863 620 26740706_c2_378 734 17305 939 312 13025805_c2_382 735 17306 441 146 106 −6 Trypanosoma cruzi U61533 (de:trypanosoma cruzi mucin-like protein (muc.t0-1) gene, complete cds.) (nt:mucin-like protein) 16535705_c2_387 736 17307 732 243 323 −29 Streptomyces AL023517 (de:streptomyces coelicolor cosmid coelicolor 1b5.) (nt:sc1b5.14c, probable transmembrane transport) 15730157_c2_388 737 17308 1524 507 31901080_c2_389 738 17309 1278 425 1357 −138 Rhizobium Q08855 (ec:1.9.3.1) (de:subunit 1)) leguminosarum 16300656_c2_392 739 17310 222 73 267 −23 Atlantic cod P55777 (sr:,atlantic cod) (ec:1.9.3.1) (de:cytochrome c oxidase polypeptide iii,) 31457961_c2_394 740 17311 834 277 98 −3 Candida albicans CONTIG580 GTC ORF with score 474 to: 5 (ai:112109) (or:Saccharomyces cerevisiae) (de:(ygr112w) (pn:hypothetical 45:similarity to human surf-1 protein) (gn:g6150) (gtcfc:13.7) (ec:) (yg2x_yeast) (keggfc:11.2) (sgdfc:13.0.0) (db:gtc-saccharomyces cerevisiae)) 25494592_c2_397 741 17312 951 316 567 −55 Cyanobacterium S75620 (sr:pcc 6803,, pcc 6803) synechocystis (sr:pcc 6803,) 10011462_c2_403 742 17313 435 144 117 −6 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 23629535_c2_404 743 17314 1407 468 1082 −109 Salmonella P50334 (de:c4-dicarboxylate transport choleraesuis protein) serotype typhimurium 17004166_c2_405 744 17315 735 244 198 −16 no gb taxonomy AF033674 (de:pseudomonas marginalis pv. match alfalfae strain lmg2214 unknown genes.) (nt:orf1) 13019580_c2_406 745 17316 855 284 142 −6 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 12003958_c2_407 746 17317 474 157 263 −23 Aspergillus S47523 fumigatus 36525826_c2_411 747 17318 333 110 617 −60 Enterococcus CONTIG108 GTC ORF with scorc 617 to: faccalis (ai:7000759017) (or:Pseudomonas aeruginosa) 509831_c2_422 748 17319 1032 343 244 −21 Klebsiella Contig471A GTC ORF with score 277 to: pneumoniae (ai:7000775135) (or:Pseudomonas aeruginosa) 36352000_c2_424 749 17320 939 312 198 −14 Achromobacter P52686 (sr:atcc 19151,) (de:sds degradation georgiopolitanum transcriptional activation protein) 4307292_c3_435 750 17321 399 132 96 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat discoideum protein sp96) 33869528_c3_455 751 17322 432 143 131 −8 Chlamydomonas S50755 reinhardtii strain UTEX 1061 35635216_c3_456 752 17323 600 199 301 −27 Edwardsiella ictaluri AF037441 (de:edwardsiella ictaluri putative 18.8 kda protein (eip19) putative 17.8 kda protein (eip18), putative 54.5 kda protein (eip55), and putative 19.5 kda protein (eip20) genes, complete cds.) (nt:eip20; possibly antigenic to catfish) 33673588_c3_457 753 17324 1509 502 1275 −130 Edwardsiella ictaluri AF037441 (de:edwardsiella ictaluri putative 18.8 kda protein (eip19) putative 17.8 kda protein (eip18), putative 54.5 kda protein (eip55), and putative 19.5 kda protein (eip20) genes, complete cds.) (nt:eip55; antigenic to catfish) 16299016_c3_458 754 17325 519 172 210 −17 Edwardsiella ictaluri AF037441 (de:edwardsiella ictaluri putative 18.8 kda protein (eip19), putative 17.8 kda protein (eip18), putative 54.5 kda protein (eip55), and putative 19.5 kda protein (eip20) genes, complete cds.) (nt:eip18; possibly antigenic to catfish) 16254058_c3_460 755 17326 792 263 317 −29 Enterobacter cloacae CONTIG435 GTC ORF with score 317 to: (ai:7000759066) (or:Pseudomonas aeruginosa) 31923781_c3_462 756 17327 420 139 117 −6 equine herpesvirus P28968 (sr:ab4p,ehv-1) (de:glycoprotein x type 1 EVH-1 precursor) 36031376_c3_466 757 17328 966 321 116 −4 pig roundworm A44982 (cl:unassigned collagens) (sr:, pig roundworm) 10241705_c3_467 758 17329 435 144 122 −8 Homo sapiens I53641 (sr:, man) (mp:11p15.5 p15.5) 11039212_c3_470 759 17330 1953 650 827 −82 Escherichia coli AF044503 (de:excherichia coli strain ec11 unknown (498), hep gene, complete cds; and rhsg accessory genetic element vgrg protein, core component and dsorf-g1 genes, complete cds.) 5322840_c3_476 760 17331 2250 749 978 −98 Escherichia coli AF044503 (de:excherichia coli strain ec11 unknown (498), hep gene, complete cds; and rhsg accessory genetic element vgrg protein, core component and dsorf-g1 genes, complete cds.) 26302292_c3_477 761 17332 477 158 32662627_c3_479 762 17333 1980 659 16151056_c3_487 763 17334 609 202 120 −5 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 260811_c3_488 764 17335 1371 456 178 −10 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 35586567_c3_491 765 17336 1335 444 483 −47 Rickettsia AJ235269 Rickettsia prowazekii strain prowazekii Madrid E, complete genome. 4425963_c3_492 766 17337 360 119 202 −15 Nitrobacter X89566 (ec:1.9.3.1) (de:n. winogradskyi dna winogradskyi for coxa, coxb and coxc genes.) 10026907_c3_494 767 17338 843 280 296 −26 Homo sapiens AF044321 (fn:controls the formation (possibly by catalyzing) (sr:human) (de:homo sapiens cytochrome c oxidase assembly protein cox11 (cox11) mrna, complete cds.) (nt:yeast cox11 ortholog; putative heme a) 22445443_c3_495 768 17339 744 247 114 −3 infectious bovine AJ004801 (de:bovine herpesvirus rhinotracheitis virus 1 complete genome.) 14927156_c3_498 769 17340 801 266 25979568_c3_499 770 17341 1188 395 143 −7 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 10161292_c3_501 771 17342 771 256 223 −18 Pseudomonas P47206 (sr:, pseudomonas perfectomarina) stutzeri (de:hypothetical protein in apt 3′ region (fragment)) 35417643_c3_503 772 17343 642 213 359 −33 Mycobacterium Z95150 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome: segment 135/162.) (nt:rv3095, (mtcy164.06), len: 158. possible) 29806932_c3_512 773 17344 864 287 162 −10 Streptomyces P32425 (de:hypothetical transcriptional ambofaciens regulator in instable dna locus (orf 1)) 16978201_c3_515 774 17345 912 303 1137 −115 Enterococcus CONTIG108 GTC ORF with score 1137 to: faecalis (ai:7000759121) (or:Pseudomonas aeruginosa) 1307282_c3_519 775 17346 819 272 15823567_c3_520 776 17347 354 117 419 −39 Escherichia coli P16680 (de:phna protein) 16301416_c3_522 777 17348 570 189 361 −33 Klebiella Contig329A GTC ORF with score 361 to: pneumoniae (ai:7000759128) (or:Pseudomonas aeruginosa) 16876327_c3_524 778 17349 786 261 265 −23 Klebsiella Contig471A GTC ORF with score 265 to: pneumoniae (ai:7000759130) (or:Pseudomonas aeruginosa) 12900157_c3_526 779 17350 1317 438 217 −15 Klebsiella Contig536A GTC ORF with score 238 to: pneumoniae (ai:7000809741) (or:Pseudomonas aeruginosa) 26835406_c3_529 780 17351 855 284 267 −23 Klebsiella Contig551A GTC ORF with score 274 to: pneumoniae (ai:7000809943) (or:Pseudomonas aeruginosa) 32674193_c3_530 781 17352 762 253 157 −12 Klebsiella Contig551A GTC ORF with score 180 to: pneumoniae (ai:7000810058) (or:Pseudomonas aeruginosa) 16616588_f1_1 782 17353 201 66 24323592_f1_2 783 17354 225 74 10003966_f1_12 784 17355 2259 752 1264 −129 Klebsiella Contig402A GTC ORF with score 1331 to: pneumoniae (ai:7000838221) (or:Enterobacter cloacae) 32680433_f1_19 785 17356 498 165 283 −25 Escherichia coli P31055 (ec:4.1.2.25) (de:probable dihydroneopterin aldolase, (dhna)) 7206393_f1_24 786 17357 1491 496 757 −75 Enterobacter cloacae CONTIG387 GTC ORF with score 911 to: (ai:7501737381) (or:Klebsiella pneumoniae) 24652167_f1_25 787 17358 747 248 249 −21 Klebsiella Contig500A GTC ORF with score 249 to: pneumoniae (ai:7000759161) (or:Pseudomonas aeruginosa) 15822151_f1_26 788 17359 1617 538 1006 −102 Klebsiella Contig500A GTC ORF with score 1006 to: pneumoniae (ai:7000759162) (or:Pseudomonas aeruginosa) 31453283_f1_27 789 17360 606 201 190 −15 Enterobacter cloacae CONTIG287 GTC ORF with score 514 to: (ai:7501763901) (or:Klebsiella pneumoniae) 14175961_f1_28 790 17361 1170 389 265 −23 Klebsiella Contig426A GTC ORF with score 423 to: pneumoniae (ai:7000825490) (or:Enterobacter cloacae) 6523961_f1_31 791 17362 1050 349 328 −30 Enterobacter cloacae CONTIG421 GTC ORF with score 328 to: (ai:7000759167) (or:Pseudomonas aeruginosa) 25822527_f1_36 792 17363 1644 547 14338907_f1_50 793 17364 2508 835 367 −32 Ralstonia S41544 solanacearum 12679811_f1_51 794 17365 678 225 427 −40 Ralstonia I40540 (cl:response regulator homology) solanacearum 34164162_f1_54 795 17366 750 249 397 −37 Clostridium Contig075H GTC ORF with score 397 to: acetobutylicum (ai:7000759190) (or:Pseudomonas aeruginosa) 33489562_f1_61 796 17367 672 223 107 −6 Enterobacter cloacae CONTIG408 GTC ORF with score 169 to: (ai:7000804017) (or:Pseudomonas aeruginosa) 3335336_f2_70 797 17368 2955 984 99 −1 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) georgiopolitanum dna) (de:pseudomonas sp. (strain imt37) monooxygenase subunit gene, completecds.) 16033543_f2_72 798 17369 660 219 609 −60 Enterobacter cloacae CONTIG490 GTC ORF with score 609 to: (ai:7000759208) (or:Pseudomonas aeruginosa) 20961456_f2_73 799 17370 786 261 106 −3 Schizosaccharomyces Z95620 (sr:fission yeast) (de:s. pombe pombe chromosome ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 12128332_f1_75 800 17371 1533 510 235 −19 Enterobacter cloacae CONTIG490 GTC ORF with score 436 to: (ai:7501727989) (or:Klebsiella pneumoniae) 7322675_f2_78 801 17372 1206 401 1248 −127 Escherichia coli F65094 (cl:o-sialoglycoprotein endopeptidase) (ec:3.4.24.57) (mp:67 min) 7161628_f2_79 802 17373 522 173 107 −6 Klebsiella Contig362A GTC ORF with score 348 to: pneumoniae (ai:7000838282) (or:Enterobacter cloacae) 1182256_f2_80 803 17374 1014 337 120 −7 Klebsiella Contig362A Klebsiella pneumoniae, GTC, rel pneumoniae 1.0, 9812146 16807333_f2_96 804 17375 288 95 90 −5 Klebsiella Contig426A GTC ORF with score 90 to: pneumoniae (ai:7000759232) (or:Pseudomonas aeruginosa) 14894375_f2_102 805 17376 336 111 3254141_f2_106 806 17377 777 258 228 −19 Streptomyces griseus P08075 (cc:2.7.7.24) (de:enzyme)) 16900040_f2_116 807 17378 1212 403 407187_f2_117 808 17379 1197 398 713 −70 Archaeoglobus G69450 (cl:atp-binding cassette homology) fulgidus 25660031_f2_119 809 17380 2367 788 35802013_f2_122 810 17381 933 310 957 −96 Pseudomonas putida P42509 (de:hypothetical protein in type 5′ region (fragment)) 11800081_f2_123 811 17382 1506 501 2524 −262 Pseudomonas P20580 (ec:4.1.3.27) (de:anthranilate aeruginosa synthase component i,) 2458252_f3_130 812 17383 210 69 34650842_f3_151 813 17384 318 105 186 −15 Klebsiella Contig362A GTC ORF with score 186 to: pneumoniae (ai:7000759287) (or:Pseudomonas aeruginosa) 22549066_f3_152 814 17385 891 296 214 −17 Aquifex acolicus C70315 31535125_f3_157 815 17386 1527 508 337 −31 Klebsiella Contig500A GTC ORF with score 337 to: pneumoniae (ai:7000759293) (or:Pseudomonas aeruginosa) 16148526_f3_161 816 17387 507 168 142 −10 Klebsiella Contig533A GTC ORF with score 142 to: pneumoniae (ai:7000759297) (or:Pseudomonas aeruginosa) 31892931_f3_163 817 17388 1575 524 232 −19 Klebsiella Contig426A GTC ORF with score 321 to: pneumoniae (ai:7000825513) (or:Enterobacter cloacae) 16289583_f3_165 818 17389 1296 431 202 −16 Klebsiella Contig426A GTC ORF with score 303 to: pneumoniae (ai:7000825478) (or:Enterobacter cloacae) 25594452_f3_172 819 17390 1017 338 250 −21 Chlorobium tepidum U58313 (de:chlorobium tepidum 7.5 kda chlorosome protein (csmb) gene, completecds.) (nt:orft) 12925930_f3_173 820 17391 1284 427 217 −17 Coxiella burnetii Q45885 (de:dnaj-like protein djla (mucoidy activation protein mucz)) 14664193_f3_181 821 17392 1047 348 410 −38 Agrobacterium U60011 (de:agrobacterium tumefaciens tumefaciens (TI plasmid pti15955 occr (occr) gene, PLASMID partial cds; mcl pseudogene, PTIBO542) complete sequence; trar-like regulator (trlr), motd (motd), motc (motc), motb (motb), and mota (mota) genes, complete cds; and unknown genes,) (nt . . . 14927093_f3_184 822 17393 1131 376 446 −42 Agrobacterium U60011 (de:agrobacterium tumefaciens tumefaciens (TI plasmid pti15955 occr (occr) gene, PLASMID partial cds; mel pseudogene, PTIBO542) complete sequence; trar-like regulator (trlr), motd (motd), motc (motc), motb (motb), and mota (mota) genes, complete cds; and unknown genes,) (nt . . . 25494405_f3_185 823 17394 1362 453 503 −48 Agrobacterium U60011 (de:agrobacterium tumefaciens tumefaciens (TI plasmid pti15955 occr (occr) gene, PLASMID partial cds; mel pseudogene, PTIBO542) complete sequence; trar-like regulator (trlr), motd (motd), motc (motc), motb (motb), and mota (mota) genes, complete cds; and unknown genes,) (nt . . . 31644842_f3_186 824 17395 936 311 489 −47 Agrobacterium U60011 (de:agrobacterium tumefaciens tumefaciens (TI plasmid pti15955 occr (occr) gene, PLASMID partial cds; mel pseudogene, PTIBO542) complete sequence; trar-like regulator (trlr), motd (motd), motc (motc), motb (motb), and mota (mota) genes, complete cds; and unknown genes,) (nt . . . 34375780_f3_187 825 17396 693 230 867 −87 Escherichia coli P32661 (ec:5.1.3.1) (de:epimerase) (ppe) (r5p3e)) 14103766_c1_204 826 17397 279 92 129 −9 Clostridium Contig146H GTC ORF with score 129 to: acetobutylicum (ai:7000759340) (or:Pseudomonas aeruginosa) 13141382_c1_219 827 17398 597 198 135 −7 Homo sapiens PN0099 (sr:, man) 36148901_c1_220 828 17399 2577 858 437 −40 Clostridium Contig075H GTC ORF with score 437 to: acetobutylicum (ai:7000759356) (or:Pseudomonas aeruginosa) 32695391_c1_225 829 17400 639 212 104 −3 Mycobacterium P96942 (ec:3.4.24.—) (de:cell division tuberculosis protein ftsh homolog,) 33864213_c1_232 830 17401 1725 574 1551 −159 Escherichia coli AB011549 (sr:escherichia coli (str:o157:h7, sub_str:rimd 0509952) (de:escherichia coli plasmid po157 dna, complete sequence.) (nt:putative reverse transcriptase; similar to) 36134583_c1_233 831 17402 2907 968 503 −89 Escherichia coli P31554 (de:organic solvent tolerance protein precursor) 26272892_c1_234 832 17403 702 233 106 −3 Klebisella Contig501A GTC ORF with score 1258 to: pneumoniae (ai:1500687053) (or:Escherichia coli) (ec:2.7.4.7) (de:(hmp-p kinase)) 30205441_c1_235 833 17404 1416 471 1002 −101 Escherichia coli P19624 (de:pyridoxal phosphase biosynthetic protein pdxa) 13145656_c1_236 834 17405 906 301 130 −5 Homo sapiens L12347 (sr:homo sapiens (library: atcc 1136, stratagene) (female embryonal cdn) (de:homo sapiens collagen chain mrna, 3′ end. 21735288_c1_237 835 17406 1260 419 692 −68 Escherichia coli P05637 (ec:3.6.1.41) (de:(diadenosine tetraphosphatase)) 12972001_c1_239 836 17407 2169 722 2647 −275 Escherichia coli P77391 (de:hypothetical 74.5 kd protein in gapa-rnd intergenic region) 26345182_c1_241 837 17408 918 305 113 −6 longfin squid S56117 (sr:, longfin squid) 2132953_c1 _242 838 17409 1821 606 1880 −194 Escherichia coli P29013 (de:hypothetical 60.8 kd protein in fadr-dada intergenic region) 6453580_c1_243 839 17410 891 296 121 −4 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10969143_c1_256 840 17411 1860 619 3084 −9999 Pseudomonas P26480 (de:rna polymerase sigma factor rpod aeruginosa (sigma-70)) 12307191_c1_257 841 17412 1494 497 12541430_c1_258 842 17413 225 74 95 −4 Homo sapiens AB014562 (sr:homo sapiens adult male brain cdna to mrna, clone_:pbluescripti) (de:homo sapiens mrna for kiaa0662 protein, partial cds.) 32553806_c1_259 843 17414 420 139 130 −7 Saccharomyces P08640 (sr:, baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 32245768_c2_272 844 17415 480 159 264 −23 Klebsiella Contig472A GTC ORF with score 264 to: pneumoniae (ai:7000759408) (or:Pseudomonas aeruginosa) 16015816_c2_274 845 17416 2298 765 96 −2 mice|C57BL/6xCBA/ U46463 (sr:house mouse) (de:mus musculus CaJ hybrid glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 12995463_c2_275 846 17417 1266 421 20025688_c2_277 847 17418 1215 404 12632331_c2_279 848 17419 867 288 392 −37 Clostridium Contig075H GTC ORF with score 392 to: acetobutylicum (ai:7000759415) (or:Pseudomonas aeruginosa) 31409752_c2_284 849 17420 1083 360 111 −3 Drosophila K02621 (sr:d. melanogaster dna, clone tm17) melanogaster (de:d. melanogaster tropomyosin gene isoform 33 (9c), exon 10c.) (nt:tropomyosin isoform 33 (9c)) 16928902_c2_297 850 17421 411 136 124 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 23204058_c2_298 851 17422 1344 447 831 −83 Escherichia coli P21202 (ec:5.2.1.8) (de:sura), (ppiase) (rotamase c)) 2474137_c2_302 852 17423 873 290 670 −66 Escherichia coli P06992 (ec:2.1.1.—) (de:dimethyltransferase)) 15048505_c2_303 853 17424 417 138 352 −32 Escherichia coli P05636 (de:apag protein) 15666633_c2_306 854 17425 432 143 273 −24 Escherichia coli P09390 (de:glpe protein) 31757091_c2_309 855 17426 429 142 151 −10 Litomosoides U54556 (de:litomosoides sigmodontis sigmodontis microfilarial sheath proteins shp3a (shp3a) and shp3 (shp3) genes, complete cds.) (nt:structural protein; similar to shp3 genes from) 4304193_c2_311 856 17427 1281 426 1318 −134 Escherichia coli P76235 (de:hypothetical 49.4 kd protein in gapa-rnd intergenic region) 12363180_c2_313 857 17428 618 205 21661006_c2_315 858 17429 1662 553 140 −5 Streptomyces AL031124 (de:streptomyces coelicolor cosmid coelicolor 1c2.) (nt:sc1c2.25c, unknown,: 1329 aa; contains two) 32525341_c2_316 859 17430 852 283 114 −3 Oryctolagus D14157 (sr:oryctolagus cuniculus edna cuniculus to mrna) (de:rabbit mrna for rabbit brain calcium channel biii, complete cds.) (nt:alpha-1 subunit) 31928892_c2_317 860 17431 471 156 122 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 3334408_c2_318 861 17432 408 135 343 −31 Pseudomonas putida AF014397 (de:pseudomonas putida macromolecular synthesis operon: 30s subunitribosomal protein s21 (rpsu), dna primase (dnag), and sigma-70 (rpod) genes, complete cds.) 32282155_c2_319 862 17433 519 172 346 −31 Legionella U63641 (fn:unknown) (de:legionella pneumophilia pneumophila rpod operon lporfx, lpdnag, and lprpodgenes, complete cds.) 12704131_c2_320 863 17434 1788 595 205 −13 Bos primigenius P23206 (sr:, bovine) (de:collagen 1(x) taurus chain precursor) 35822906_c2_324 864 17435 2970 989 308 −23 Bordetella pertussis P16575 (ec:2.7.3.—) (de:virulence sensor protein bvgs precursor,) 21734502_c2_325 865 17436 1014 337 95 −2 Aspergillus Contig8669 GTC ORF with score 124 to: fumigatus (ai:5500701392) (or:Nephila clavipes) (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds. 10178250_c2_331 866 17437 261 86 24495341_c3_333 867 17438 855 284 1310 −133 Pseudomonas Q06553 (de:transcription rcgulatory protein aeruginosa prtr (pyosin repressor protein)) 22461557_c3_334 868 17439 375 124 515 −49 Pseudomonas Q06552 (de:transcription regulatory protein aeruginosa prtn (pyocin activator protein)) 31894767_c3_336 869 17440 2142 713 149 −10 Klebsiella Contig472A GTC ORF with score 149 to: pneumoniae (ai:7000759472) (or:Pseudomonas aeruginosa) 1308530_c3_337 870 17441 360 119 131 −9 Enterobacter cloacae CONTIG487 GTC ORF with score 131 to: (ai:7000759473) (or:Pseudomonas aeruginosa) 7115706_c3_338 871 17442 417 138 125 −8 Enterobacter cloacae CONTIG399 GTC ORF with score 115 to: (ai:58918) (or:Saccharomyces cerevisiae) (mp: 14r) 2000457_c3_344 872 17443 786 261 305 −27 Klebsiella Contig545A GTC ORF with score 598 to: pneumoniae (ai:7000845728) (or:Enterobacter cloacae) 30367781_c3_349 873 17444 417 138 116 −7 Pseudomonas S29309 aeruginosa 26821906_c3_358 874 17445 189 62 29782330_c3_367 875 17446 279 92 100 −6 Aspergillus Contig10074 GTC ORF with score 200 to: fumigatus (ai:58918) (or:Saccharomyces cerevisiae) (mp: 14r) 16894580_c3_374 876 17447 822 273 115 −4 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 9866583_c3_376 877 17448 477 158 133 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35253277_c3_378 878 17449 807 268 114 −3 Canadian hard S18733 (cl:glutenin) (sr:, common wheat) winter wheat 6360418_c3_380 879 17450 501 166 168 −12 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10824040_c3_381 880 17451 492 163 117 −6 Schizosaccharomyces Z95620 (sr:fission yeast) (de:s. pombe pombe chromosome ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial: serine rich,) 2400181_c3_382 881 17452 1374 457 107 −3 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 10291433_c3_384 882 17453 1365 454 1253 −127 Escherichia coli P06961 (ec:2.7.7.25) (de:(trna cca- pyrophosphorylase)) 11956437_c3_387 883 17454 666 221 366 −33 Escherichia coli P31056 (de:hypothetical 22.2 kd protein in baca-ttda intergenic region (o205)) 35258326_c3_388 884 17455 1059 352 339 −31 Enterobacter cloacae CONTIG490 GTC ORF with score 339 to: (ai:7000759524) (or:Pseudomonas aeruginosa) 10286467_c3_389 885 17456 2097 698 2442 −253 Pseudomonas putida AF014397 (de:pseudomonas putida macromolecular synthesis operon: 30s subunitribosomal protein s21 (rpsu), dna primase (dnag), and sigma-70 (rpod) genes, complete cds.) 17082636_c3_397 886 17457 2472 823 1346 −137 Cyanobacterium S74707 (cl:response regulator homology) synechocystis (sr:pcc 6803, pcc 6803) (sr:pcc 6803,) 33867338_c3_399 887 17458 1698 565 1532 −157 Escherichia coli AB011549 (sr:escherichia coli (str:o157:h7, sub_str:rimd 0509952) (de:escherichia coli plasmid po157 dna, complete sequence.) (nt:putative reverse transcriptase: similar to) 16588533_f1_1 888 17459 1425 474 148 −7 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt: 160 kda) 16541303_f1_5 889 17460 1944 647 585 −57 Bacillus Z93940 (de:b. subtilis genomic dna fragment subtilis/Bacillus from yuca to yuch.) (nt:putative) globigii 12245687_f1_6 890 17461 819 272 142 −7 Caenorhabditis Q09456 (de:putative cuticle collagen c09g5.5) elegans 31657277_f1_7 891 17462 2001 666 638 −62 Bacillus C69830 subtilis/Bacillus globigii 12157700_f1_8 892 17463 1257 418 127 −4 Gallus gallus A90458 (cl:collagen alpha 1(i) chain:fibrillar domesticus collagen carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 12291263_f1_9 893 17464 678 225 131 −7 Homo sapiens A60533 (sr:, man) (mp:1q21-q24) 14583507_f1_10 894 17465 468 155 146 −9 Homo sapiens O00268 (sr:, human) (de:(tafii135) (tafii-130) 32547642_f1_13 895 17466 363 120 126 −7 Homo sapiens AB011108 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0536 protein, partial cds.) 13022906_f1_15 896 17467 1470 489 108 −3 Home sapiens I72525 (sr:, man) 32134817_f1_18 897 17468 1524 507 288 −25 Enterobacter cloacae CONTIG447 GTC ORF with score 1123 to: (ai:7501774336) (or:Klebsiella pneumoniae) 16876080_f1_20 898 17469 1788 595 887 −89 Escherichia coli P39455 (de:hypothetical 46.6 kd protein in phep-nfnb intergenic region) 35828950_f1_22 899 17470 639 212 234 −20 Acinetobacter CONTIG180 GTC ORF with score 124 to baumannii C (ai:7000694271) (or:Bacillus subtilis) 31532091_f1_26 900 17471 435 144 175 −13 Pseudomonas AF054868 (de:pseudomonas aeruginosa aeruginosa autoinducer synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phec), hypothetical 0299 protein (yigm), chloramphenicol-sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete . . . 15128326_f1_28 901 17472 1140 379 171 −9 no gb taxonomy U52064 (de:kaposi's sarcoma-associated match herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 22087791_f1_29 902 17473 201 66 33726083_f1_34 903 17474 471 156 189 −15 Enterobacter cloacae CONTIG147 GTC ORF with score 189 to: (ai:7000759570) (or:Pseudomonas aeruginosa) 32681533_f1_39 904 17475 1254 417 419 −39 Klebsiella Contig501A GTC ORF with score 820 to: pneumoniae (ai:7000821374) (or:Enterobacter cloacae) 24472842_f1_41 905 17476 447 148 144 −9 Saccharomyces P32323 (sr:, baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 34267082_f1_43 906 17477 465 154 141 −10 Pyrus communis U14009 (sr:pear) (de:pyrus communis arabinogalactan-protein (agp) mrna, complete cds.) 2992951_f1_44 907 17478 714 237 102 −2 Streptomyces griseus P54742 (ec:2.7.1.—) (de:serine/threonine protein kinase afsk,) 32520431_f1_45 908 17479 903 300 11745802_f1_47 909 17480 765 254 581 −56 Escherichia coli F64919 14300833_f1_48 910 17481 486 161 118 −6 Apspergillus Contig8154 GTC ORF with score 433 to: fumigatus (ai:177837) (or:Zea mays) (sr:, maize) 25886567_f1_53 911 17482 870 289 123 −7 Aspergillus Contig1817 GTC ORF with score 143 to: fumigatus (gn:wsp1+) (fn:actin patch assembly and localization) (sr:fission yeast) (de:schizosaccharomycepombe wiskott-aldrich syndrome protein homolog (wsp1+) gene, complete cds, and btf3/beta-nac gene, partialsequence.) (nt:wasp 32605166_f1_54 912 17483 1080 359 409 −38 Escherichia coli A64920 11727182_f1_55 913 17484 714 237 258 −22 Rhodobacter S39906 capsulatus 16067806_f1_57 914 17485 1308 435 30330168_f1_58 915 17486 315 104 90 −3 herpes simplex virus Z86099 (fn:internal protein of immature type 2 HSV-2 capsids) (de:herpes simplex virus type 2 (strain hg52), complete genome.) 35799156_f1_59 916 17487 558 185 97 −4 Mycobacterium AL123456 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 120/162.) (nt:rv2703, (mtcy05a6.24), len: 528. function: siga.) 6535287_f1_71 917 17488 420 139 387 −36 Klebsiella Contig516A GTC ORF with score 612 to: pneumoniae (ai:7000845890) (or:Enterobacter cloacae) 29791287_f1_73 918 17489 417 138 415 −39 Enterobacter cloacae CONTIG210 GTC ORF with score 415 to: (ai:7000759609) (or:Pseudomonas aeruginosa) 2227155_f1_80 919 17490 2391 796 32557837_f1_81 920 17491 1197 398 1644 −169 Pseudomonas P72170 (ec:3.5.2.3) (de:dihydroorotase, aeruginosa (dhoase)) 16204833_f1_84 921 17492 894 297 384 −36 Klebsiella Contig546A GTC ORF with score 716 to: pneumoniae (ai:7000835662) (or:Enterobacter cloacae) 25402126_f1_86 922 17493 549 182 642 −63 Azotobacter P22759 (de:bacterioferritin (bfr) vinelandii (cytochrome b-557.5)) 31379791_f1_91 923 17494 2433 810 7150708_f1_96 924 17495 876 291 250 −20 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at _ conserved spacers r or) 33647337_f1_101 925 17496 939 312 117 −4 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 12972212_f1_102 926 17497 552 183 96 −5 Klebsiella Contig547A GTC ORF with score 117 to: pneumoniae (ai:7000786349) (or:Pseudomonas aeruginosa) 5103457_f1_104 927 17498 783 260 878 −88 Escherichia coli P11288 (de:hypothctical 29.6 kd protein in thrc-talb intergenic region) 30704517_f1_108 928 17499 1260 419 90 −1 Mycobacterium Q50589 (de:hypothetical protein cy19g5.10 tuberculosis (fragment)) 25556931_f1_111 929 17500 1263 420 1397 −143 Pseudomonas L22611 (fn:related to alginate biosynthesis.) aeruginosa (sr:pseudomonas aeruginosa (strain 8830) dna) (de:pseudomonas aeruginosa alginate synthesis related protein (alg44)gene, complete cds, algd and alg8 genes, 3′ end and 5′ end.) 25881706_f1_112 930 17501 4563 1520 2808 −292 Pseudomonas U27829 (de:pseudomonas aeruginosa aeruginosa alginate-c5-mannuronan-epimerase (algg), algx (algx) and alginate lyase (algl) genes, complete cds.) 32300818_f1_113 931 17502 1437 478 2476 −257 Pseudomonas U27829 (de:pseudomonas aeruginosa aeruginosa alginate-c5- mannuronan-epimerase (algg), algx (algx) and alginate lyase (algl) genes, complete cds.) 14650332_f1_114 932 17503 1107 368 1915 −198 Pseudomonas A40610 (ec:4.2.2.3) aeruginosa 32307942_f1_116 933 17504 2766 921 2028 −210 Pseudomonas U50202 (fn:required for alginate aeruginosa o-acctylation) (sr:pseudomonas aeruginosa strain=frd1) (de:pseudomonas aeruginosa alginate gene cluster algi (algi), algj (algj) and algf (algf) genes. complete cds.) 24102192_f1_117 934 17505 675 224 1113 −113 Pseudomonas U50202 (fn:required for alginate aeruginosa o-acctylation) (sr:pseudomonas aeruginosa strain=frd1) (de:pseudomonas aeruginosa alginate gene cluster algi (algi), algj (algj) and algf (algf) genes, complete cds.) 12142316_f1_118 935 17506 1578 525 115 −4 Orf virus B34768 13922006_f1_119 936 17507 1188 395 1302 −133 Escherichia coli P77690 (de:hypothctical 42.9 kd protein in ais-pmrd intergenic region) 31897681 _f1_121 937 17508 3195 1064 1002 −101 Salmonella AF036677 (de:salmonella typhimurium putative choleraesuis operon regulated by pmrab, necessary serotype for 4-aminoarabinose lipid a typhimurium modification and polymyxinresistance, pmrg (pmrg) gene, partial cds; pmrf (pmrf) gene and 6orfs, complete cds: and pmrd (pmrd) gene . . . 10830408_f1_125 938 17509 486 161 174 −13 Salmonella AF036677 (de:salmonella typhimurium putative choleraesuis operon regulated by pmrab, necessary serotype for 4-aminoarabinose lipid a typhimurium modification and polymyxinresistance, pmrg (pmrg) gene, partial cds; pmrf (pmrf) gene and 6orfs, complete cds: and pmrd (pmrd) gene . . . 13022780_f1_128 939 17510 573 190 296 −26 Aquifex aeolicus H70301 16100341_f1_129 940 17511 861 287 409 −38 Enterobacter cloacae CONTIG266 GTC ORF with score 566 to: (ai:7501773210) (or:Klebsiella pneumoniae) 1367341_f2_130 941 17512 1065 354 409 −37 Escherichia coli B65005 14706583_f2_135 942 17513 1890 629 402 −34 Anabaena flos-aquae AJ005201 (fn:catalyzes atp-dependent formation (strain IUCC 1444) of) (de:anabaena variabilis cphb and cpha genes, complete.) 34073967_f2_137 943 17514 408 135 155 −10 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 33876633_f2_139 944 17515 2859 952 593 −55 Pseudomonas AF030352 (de:pseudomonas aeruginosa two aeruginosa component sensor (lema) gene, partialcds.) (nt:protein histidine kinase; similar to p. fluorescens) 14940632_f2_143 945 17516 1839 612 331 −29 Mycobacterium U46844 (de:mycobacterium smegmatis smegmatis catalase-peroxidase (katg), putativearabinosyl transferase (embc, emba, embb), genes complete cds andputative propionyl-coa carboxylase beta chain (pccb) genes, partialcds.) (nt:orf7; hypothetical membrane. . . 3135028_f2_146 946 17517 1092 363 107 −2 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HRV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b) 36067901_f2_147 947 17518 1230 409 10042665_f2_150 948 17519 711 236 304 −27 Bacillus P45862 (de:hypothetical 19.6 kd protein in subtilis/Bacillus acda 5′ region) globigii 32241283_f2_152 949 17520 1143 380 227 −17 Klebsiella Contig543A GTC ORF with score 888 to: pneumoniae (ai:7000830083) (or:Enterobacter cloacae) 5105408_f2_153 950 17521 804 267 400 −37 Klebsiella Contig543A GTC ORF with score 888 to: pneumoniae (ai:7000830083) (or:Enterobacter cloacae) 33711431_f2_154 951 17522 651 216 714 −70 Pseudomonas AF054868 (de:pseudomonas aeruginosa aeruginosa autoinducer synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phec), hypothectical 0299 protein (yigm), chloramphenicol-sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete . . . 4554762_f2_176 952 17523 2115 704 150 −7 Burkholderia U41162 (sr:burkholderia cepacia cepacia strain=17616) (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 12187843_f2_179 953 17524 630 209 703 −69 Escherichia coli E64919 14975830_f2_181 954 17525 693 230 141 −7 Micrococcus luteus JQ0405 14713966_f2_184 955 17526 504 167 112 −5 mice|C57BL/6xCBA/ Q06666 (sr:, mouse) (de:octapeptide-repeat CaJ hybrid protein t2) 34507215_f2_185 956 17527 282 93 2448806_f2_186 957 17528 1038 345 690 −68 Escherichia coli P76182 (de:hypothetical 38.1 kd protein in add-nth intergenic region) 16917817_f2_188 958 17529 549 182 383 −35 Haemophilus Q57020 (de:hypothetical protein hi1688) influenzae 12554135_f2_195 959 17530 1515 504 161 −11 Klebsiella Contig541A GTC ORF with score 278 to: pneumoniae (ai:7000809606) (or:Pseudomonas aeruginosa) 16025652_f2_197 960 17531 237 78 115 −7 Klebsiella Contig541A GTC ORF with score 403 to: pneumoniae (ai:7000809729) (or:Pseudomonas aeruginosa) 15815967_f2_204 961 17532 732 243 130 −5 Escherichia coli D90774 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 12206261_f2_216 962 17533 255 84 115 −6 Pseudomonas P72170 (ec:3.5.2.3) (de:dihydroorotase, aeruginosa (dhoase)) 31679208_f2_218 963 17534 615 204 110 −3 Alphaherpesvirus P11675 (sr:indiana-funkhauser/becker, prv) pseudorabies virus (de:immediate-early protein ie180) PRV 10163186_f2_222 964 17535 282 93 121 −8 Cyanobacterium S77421 (sr:pcc 6803,, pcc 6803) synechocystis (sr:pcc 6803,) 11133405_f2_223 965 17536 1389 462 157 −8 Trypanosoma cruzi A44937 (cl:kinetoplast-associated protein) 11844541_f2_234 966 17537 537 178 99 −5 longfin squid S56117 (sr:, longfin squid) 13063506_f2_235 967 17538 891 296 127 −6 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence} (mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 15797217_f2_237 968 17539 324 107 34416680_f2_240 969 17540 924 307 1553 −159 Pseudomonas A32013 (cl:ornithine aeruginosa carbamoyltransferase: aspartate/ornithine carbamoyltransferase homology) (ec:2.1.3.3) 13095158_f2—241 970 17541 999 332 145 −10 Enterobacter cloacae CONTIG483 GTC ORF with score 190 to: (ai:7000771209) (or:Pseudomonas aeruginosa) 22158443_f2_246 971 17542 1368 455 2236 −232 Pseudomonas P11759 (ec:1.1.1.132) (de:gdp-mannose 6- aeruginosa dehydrogenase, (gmd)) 12605031_f2_252 972 17543 1461 486 2426 −252 Pseudomonas X99206 (de:p. aeruginosa algk gene and aeruginosa partial alg44 and alge genes.) 16897567_f2_253 973 17544 1335 444 2170 −225 Pseudomonas P18895 (de:alginate production protein alge aeruginosa precursor) 26438166_f2_263 974 17545 1584 527 2734 −284 Pseudomonas U50202 (fn:required for alginate aeruginosa o-acetylation) (sr:pseudomonas aeruginosa strain=frd1) (de:pseudomonas aeruginosa alginate gene cluster algi (algi), algj (algj) and algf (algf) genes, complete cds.) 34089530_f2_264 975 17546 531 176 151 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 25433342_f2_266 976 17547 1653 550 2482 −258 Pseudomonas P07874 (cc:5.3.1.8:2.7.7.22) (de:(gdp), aeruginosa (gdp-mannose pyrophosphorylase) (gmp)) 14551908_f2_270 977 17548 3114 1037 2396 −249 Escherichia coli E64996 12755032_f2_273 978 17549 1692 563 162 −8 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid elegans c18h7.) (nt:similar to cuticular collagen; c18h7.3) 16220816_f2_274 979 17550 597 198 211 −17 Salmonella AF036677 (de:salmonella typhimurium putative choleraesuis operon regulated by pmrab, necessary serotype for 4-aminoarabinose lipid a typhimurium modification and polymyxinresistance, pmrg (pmrg) gene, partial cds; pmrf (pmrf) gene and 6orfs, complete cds; and pmrd (pmrd) gene . . . 13006956_f2_275 980 17551 1083 360 149 −8 Homo sapiens AB010962 (sr:homo sapiens female uterurs cdna to mrna, clone_:lamda gt11) (de:homo sapiens mrna for mifr-2, complete cds.) (nt:metalloproteinase in the female reproductive) 24066668_f2_277 981 17552 264 87 238 −20 Enterobacter cloacae CONTIG266 GTC ORF with score 238 to: (ai:7000759813) (or:Pseudomonas aeruginosa) 26604080_f3_281 982 17553 759 252 228 −19 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna) (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:similar to :d888021 percent ident:28.708 in) 15798536_f3_286 983 17554 474 157 104 −3 Epstein-Barr virus P03181 (sr:b95-8, human herpesvirus 4) (de:hypothetical bhlf1 protein) 12771080_f3_287 984 17555 363 120 99 −4 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 13088180_f2_291 985 17556 420 139 98 −3 Homo sapiens U47924 (sr:human) (de:human chromosome 12p13 sequence, complete sequence.) (nt:human dentatorubral and pallidoluysian atrophy) 16253957_f3_300 986 17557 489 162 225 −17 Rhodobater AF016236 (de:rhodobacter sphaeroides sphaeroides dmso/tmao-sensor kinase (dors), dmso/tmao-response regulator (dorr), dmso/tmao-cytochromec-containing subunit (dorc), dmso-membrane protein (dorb), and dmso/tmao-reductase (dora) genes, complete cds.) 5208211_f3_301 987 17558 282 93 119 −8 Enterobacter cloacae CONTIG457 GTC ORF with score 318 to: (ai:112766) (or:Escherichia coli) nt:o72; 072; alternate orf with good statistics. 16931905_f3_307 988 17559 705 234 220 −17 Enterobacter cloacae CONTIG488 GTC ORF with score 274 to: (de:mycobacterium smegmatis catalase-peroxidase (katg), putativearabinosyl transferase (embc, emba, embb), genes complete cds and putative propionyl-coa carboxylase beta chain (pccb) genes, partialcds.) (nt:orf7: hypothetical . . . 32525091_f3_310 989 17560 1521 506 531 −51 Bacillus P37514 (de:hypothetical 49.7 kd protein in subtilis/Bacillus tetb-exoa intergenic region) globigii 11067658_f3_311 990 17561 1431 476 134 −6 mice|C57BL/6xCBA/ P05143 (sr:, mouse) (de:proline-rich protein CaJ hybrid mp-3 (fragment) 22074166_f3_314 991 17562 276 91 196 −16 Klebsiella Contig543A GTC ORF with score 196 to: pneumoniae (ai:7000759850) (or:Pseudomonas aeruginosa) 22665708_f3_315 992 17563 618 205 412 −39 Enterobacter cloacae CONTIG452 GTC ORF with score 412 to: (ai:7000759851) (or:Pseudomonas aeruginosa) 12210455_f3_319 993 17564 564 187 183 −13 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12632191_f3_321 994 17565 903 300 284 −25 Enterobacter cloacae CONTIG437 GTC ORF with score 299 to: (ai:7501778850) (or:Klebsiella pneumoniae) 4398533_f3_334 995 17566 2043 680 2369 −246 Escherichia coli P00959 (ec:6.1.1.10) (de:(metrs)) 32133416_f3_335 996 17567 834 277 10807330_f3_337 997 17568 489 162 122 −7 Rattus norvegicus S24169 (sr:, norwawy rat) 32661390_f3_340 998 17569 462 153 92 −2 Human P50768 (de:regulatory protein e2) papillomavirus type 22 31822191_f3_341 999 17570 2331 776 1267 −129 Escherichia coli G64919 32683157_f3_344 1000 17571 729 242 103 −3 Araneus diadematus U47856 (de:araneus diadematus fibroin-4 mrna, partial cds.) 16142202_f3_347 1001 17572 639 212 798 −79 Escherichia coli P20625 (ec:4.2.99.18) (de:lyase)) 24664753_f3_348 1002 17573 195 64 30552030_f3_351 1003 17574 423 140 93 −4 Pyrococcus AP000003 (su:pyrococcus horikoshii (str:ot3) horikoshii dna) (de:pyrococcus horikoshii ot3 genomic dna, 544001-777000 nt. position(3/7).) 12752306_f3_355 1004 17575 519 172 140 −8 Caenorhahditis AF000298 (sr:caenorhahditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 10414581_f3_362 1005 17576 3882 1293 157 −7 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 35659768_f3_365 1006 17577 486 161 99 −3 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 103887_f3_366 1007 17578 423 140 521 −50 Neisseria Y14298 (ec:4.4.1.5) (de:neisseria meningitidis meningitidis gloa gene.) (nt:subunit glyoxalase i) 21538563_f3_372 1008 17579 1266 421 704 −69 Vibrio P46232 (ec:3.1.13.—) (de:ribonuclease t, parahaemolyticus (exoribonuclease t) (rnase t)) 9891411_f3_376 1009 17580 1449 482 131 −5 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 33726452_f3_378 1010 17581 597 198 247 −21 Enterobacter cloacae CONTIG313 GTC ORF with score 247 to: (ai:7000759914) (or:Pseudomonas aeruginosa) 17050806_f3_379 1011 17582 567 188 134 −6 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 2040657_f3_384 1012 17583 3045 1014 3404 −9999 Pseudomonas AJ007828 (de:pseudomonas tolaasii cprs gene.) tolaasii 31927207_f3_385 1013 17584 549 182 125 −6 Canadian hard JN0690 (cl:glutenin) (sr:, common wheat) winter wheat 13004705_f3_386 1014 17585 1110 369 680 −67 Cyanobacterium S75652 (cl:unassigned atp-binding cassette synechocystis proteins:atp binding cassette homology) (sr:pcc 6803,, pcc 6803) (sr:pcc 6803,) 16585811_f3_391 1015 17586 1539 512 2574 −267 Pseudomonas L22611 (fn:related to alginate biosynthesis.) aeruginosa (sr:pseudomonas aeruginosa (strain 8830) dna) (de:pseudomonas aeruginosa alginate synthesis related protein (alg44) gene, complete cds, algd and alg8 genes, 3′ end and 5′ end.) (nt:initiation site unkno . . . 31447681_f3_392 1016 17587 1269 422 111 −3 Human P06422 (de:regulatory protein e2) papillomavirus type 8 10645692_f3_393 1017 17588 900 299 199 −12 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 12994405_f3_395 1018 17589 813 270 114 −3 Saccharomyces P47179 (sr:, baker's yeast) (de:precursor) cerevisiae 16094780_f3_398 1019 17590 1251 416 131 −5 Homo sapiens O00268 (sr:, human) (de:(tafii135) (tafii-130) 22945836_f3_399 1020 17591 1647 548 183 −10 Oryctolagus P27884 (sr:, rabbit) (de:brain calcium channel cuniculus bi-2 protein) 32057716_f3_400 1021 17592 1599 532 32516292_f3_403 1022 17593 918 305 152 −7 Alphaherpesvirus P11675 (sr:indiana-funkhauser/becker, prv) pseudorabies virus (de:immediate-early protein ie180) PRV 31922708_f3_405 1023 17594 918 305 151 −7 Oryctolagus P27884 (sr:, rabbit) (de:brain calcium channel cuniculus bi-2 protein) 9847802_f3_410 1024 17595 1005 334 140 −7 mice|C57BL/6xCBA/ C29149 (cl:proline-rich protein) CaJ hybrid (sr:, house mouse) 876466_f3_411 1025 17596 1191 396 1046 −106 Escherichia coli P77757 (de:hypothetical 36.3 kd protein in ais-pmrd intergenic region) 13777255_f3_417 1026 17597 1836 611 329 −27 Salmonella AF036677 (de:salmonella typhimurium choleraesuis putative operon regulated by pmrab, serotype necessary for 4-aminoarabinose lipid typhimurium a modification and polymyxinresistance, pmrg (pmrg) gene, partial cds; pmrf (pmrf) gene and 6orfs, complete cds; and pmrd (pmrd) gene . . . 25801533_f3_418 1027 17598 1257 418 836 −83 Salmonella AF036677 (de:salmonella typhimurium putative choleraesuis operon regulated by pmrab, necessary serotype for 4-aminoarabinose lipid a typhimurium modification and polymyxinresistance, pmrg (pmrg) gene, partial cds; pmrf (pmrf) gene and 6orfs, complete cds; and pmrd (pmrd) gene . . . 20875162_13_421 1028 17599 1629 542 951 −95 Xanthomonas JC2525 (ec:1.1.99.—) campestris pv. campestris 11915830_c1_423 1029 17600 723 240 766 −76 Escherichia coli P20966 (ec:2.7.1.69) (de:(ec 2.7.1.69) (eii-fru)) 16538530_c1_428 1030 17601 498 165 134 −8 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b 16510317_c1_429 1031 17602 489 162 135 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33463505_c1_430 1032 17603 1143 380 508 −49 Klebsiella Contig502A GTC ORF with score 508 to: pneumoniae (ai:7000759966) (or:Pseudomonas aeruginosa) 12991318_c1_436 1033 17604 1200 399 589 −57 Klebsiella Contig502A GTC ORF with score 589 to: pneumoniae (ai:7000759972) (or:Pseudomonas aeruginosa) 2520433_c1_439 1034 17605 1491 496 13016018_c1_444 1035 17606 1527 508 5989791_c1_445 1036 17607 2847 948 17034575_c1_450 1037 17608 1497 498 12970033_c1_458 1038 17609 984 327 248 −21 Enterobacter cloacae CONTIG393 GTC ORF with score 248 to: (ai:7000759994) (or:Pseudomonas aeruginosa) 2205407_c1_470 1039 17610 2178 725 518 −48 Mycobacterium AL021928 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 11/162.) (nt:rv0197, (mtv033.05), len: 762.unknown but similar) 35336592_c1_476 1040 17611 615 204 775 −77 Legionella L46863 (sr:legionella pneumophila pneumophila (individual_isolate philadelphia 1) dna) (de:legionella pneumophila alkylhydrogenperoxide reductase (tsaa) gene, complete cds and glutaredoxin-like protein (grla) gene, completecds.) 11192667_c1_477 1041 17612 2262 753 310 −27 Vibrio alginolyticus D84310 (sr:vibrio alginolyticus (strain:138-2) dna) (de:vibrio alginolyticus gene for rnase t and moty gene for component of sodium-driven polar flagellar motor, complete cds.) 30566441_c1_478 1042 17613 1239 412 954 −96 Rattus norvegicus P09034 (sr:, rat) (ec:6.3.4.5) (de:ligase)) 31267283_c1_483 1043 17614 1059 352 106 −2 Rattus norvegicus Q63003 (sr:, rat) (de:5e5 antigen) 35407666_c1_484 1044 17615 900 299 137 −7 Caenorhabditis P20630 (de:cuticle collagen 12 precursor) elegans 16511403_c1_485 1045 17616 2505 834 644 −63 Pseudomonas X99514 (fn:outer membrane component of aeruginosa multidrug efflux) (de:p. aeruginosa mexe, mexf & oprn genes.) 25955006_c1_487 1046 17617 252 83 180 −14 Enterobacter cloacae CONTIG210 GTC ORF with score 94 to: (ai:4000710458) (or:Synechocystis) (gtcf:14.1) (kcggfc:14.2) (kazusafc:16.1) 25631336_c1_488 1047 17618 336 111 14656417_c1_489 1048 17619 1947 648 160 −8 Homo sapiens M63730 (sr:human, cdna to mrna) (de:human bullous pemphigoid (bp180) mrna, partial cds.) 36428876_c1_490 1049 17620 1464 487 744 −74 Schizosaccharomyces AL021815 (sr:fission yeast) (de:s. pombe pombe chromosome i cosmid c8e4.) (nt:spac8e4.05c, putative cis- muconate cycloisomerase,) 10647831_c1_494 1050 17621 1449 482 413 −38 Mycobacterium AL021925 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 100/162.) (nt:rv2258c, (mtv022.08c), len: 353. unknown but) 34234808_c1_497 1051 17622 537 178 104 −3 Dictyostelium AJ224893 (fn:spore differentiation) discoidcum (de:dictyostelium discoideum srfa gene.) 29823278_c1_498 1052 17623 582 193 110 −7 Klebsiella Contig311A GTC ORF with score 164 to: pneumoniae (ai:7000822108) (or:Enterobacter cloacae) 13011578_c1_500 1053 17624 504 167 133 −9 Enterobacter cloacae CONTIG388 GTC ORF with score 133 to: (ai:7000760036) (or:Pseudomonas aeruginosa) 9813433_c1_504 1054 17625 480 159 105 −5 Aspergillus Contig9493 GTC ORF with score 181 to: fumigatus (ai:5500701468) (or:Equine herpesvirus 4) (fn:very large tegument protein) (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 35261428_c1_507 1055 17626 1131 376 351 −32 Enterobacter cloacae CONTIG388 GTC ORF with score 351 to: (ai:7000760043) (or:Pseudomonas aeruginosa) 5163581_c1_517 1056 17627 1134 377 1223 −124 Pseudomonas fragi P72190 (de:hypothetical 30.2 kd protein in capb 3′ region) 32557262_c1_520 1057 17628 897 298 92 −4 Aspergillus Contig6660 GTC ORF with score 92 to: fumigatus (ai:7000760056) (or:Pseudomonas aeruginosa) 15041631_c1_521 1058 17629 1338 445 2259 −234 Pseudomonas B53652 aeruginosa 16532941 _c1_522 1059 17630 1464 487 1046 −106 Pseudomonas P54291 (de:autoinducer synthesis protein rhli) aeruginosa 16289691_c1_524 1060 17631 2262 753 1501 −154 Pseudomonas AF054868 (de:pseudomonas aeruginosa aeruginosa autoinducer synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phcc), hypothetical 0299 protein (yigm), chloramphenicol- sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete . . . 30713192_c1_527 1061 17632 216 71 167 −12 Pseudomonas AF054868 (de:pseudomonas aeruginosa aeruginosa autoinducer synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phcc), hypothctical 0299 protein (yigm), chloramphenicol- sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete . . . 35792777_c1_532 1062 17633 1419 472 261 −22 Klebsiella Contig442A GTC ORF with score 261 to: pneumoniae (ai:7000760068) (or:Pseudomonas aeruginosa) 26660317_c1_535 1063 17634 603 200 128 −6 rainbow trout AB008374 (sr:oncorhynchus mykiss fibroblast cell_l:rtt cdna to mrna) (de:oncorhynchus mykiss mrna for alpha 3 type i collagen, partial cds.) 16275167_c1_536 1064 17635 1398 465 739 −73 Escherichia coli P21507 (de:atp-dependent rna helicase srmb) 29536267_c1_543 1065 17636 663 220 125 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16929005_c1_544 1066 17637 561 186 143 −8 Homo sapiens M94131 (sr:homo sapiens intestine cdna to mrna) (de:human mucin 2 (muc2) mrna, partial cds.) 10676666_c1_546 1067 17638 627 208 124 −5 mice|C57BL/6xCBA/ I49607 (cl:collagen alpha 1(i) chain:fibrillar CaJ hybrid collagen carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, house mouse) 7089591_c1_548 1068 17639 384 127 97 −5 Enterobacter cloacae CONTIG456 GTC ORF with score 479 to: (ai:7501757122) (or:Klebsiella pneumoniae) 13129158_c1_549 1069 17640 336 111 162 −12 Klebsiella Contig535A GTC ORF with score 479 to: pneumoniae (ai:7000846281) (or:Enterobacter cloacae) 35290711_c1_552 1070 17641 1362 453 24070918_c1_556 1071 17642 1368 455 29802083_c2_564 1072 17643 1083 360 107 −6 Aspergillus Contig7202 GTC ORF with score 107 to: fumigatus (ai:7000760100) (or:Pseudomonas aeruginosa) 13022341_c2_567 1073 17644 312 103 99 −4 Molluscum L10127 (sr:molluscum contagiosum virus type contagiosum virus 1 dna) (de:molluscum contagiosum subtype 1 virus type 1 orf1 and orf2 dna.) (nt:orf17) 26385791_c2_568 1074 17645 1083 360 108 −2 Petromyzon marinus I51116 (sr:, sea lamprey) 24714091_c2_569 1075 17646 801 266 389 −36 Klebsiella Contig502A GTC ORF with score 389 to: pneumoniae (ai:7000760105) (or:Pseudomonas aeruginosa) 10836406_c2_571 1076 17647 603 200 133 −6 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 14658567_c2_573 1077 17648 1128 375 116 −4 Saimiriine Q01042 (sr:11,) (de:immediate-early protein) herpesvirus 2 31380433_c2_597 1078 17649 639 212 109 −3 Rana catesbeiana AB015440 (sr:rana catesbeiana cdna to mrna) (de:rana catesbeiana mrna for alpha 1 type i collagen, complete cds.) 30719080_c2_600 1079 17650 1596 531 15056468_c2_604 1080 17651 1275 424 255 −22 Klebsiella Contig471A GTC ORF with score 428 to: pneumoniae (ai:7000787132) (or:Pseudomonas aeruginosa) 32557843_c2_607 1081 17652 642 213 35448283_c2_610 1082 17653 2649 882 153 −6 Chinese oak AF083334 (sr:chinese oak silkmoth) silkmoth (de:antheraea pernyi fibroin gene, complete cds.) 4509658_c2_616 1083 17654 330 109 421 −39 Escherichia coli P37010 (de:hypothetical 12.9 kd protein in lhr-sodb intergenic region) 4744840_c2_622 1084 17655 294 97 196 −16 Enterobacter cloacae CONTIG474 GTC ORF with score 196 to: (ai:7000760158) (or:Pseudomonas aeruginosa) 34095667_c2_628 1085 17656 591 196 205 −17 Enterobacter cloacae CONTIG313 GTC ORF with score 205 to: (ai:7000760164) (or:Pseudomonas aeruginosa) 36114381_c2_630 1086 17657 4404 1467 3222 −9999 Pseudomonas X99514 (fn:cytoplasmic membrane aeruginosa component of multidrug) (de:p. aeruginosa mexe, mexf & oprn genes.) 2461086_c2_636 1087 17658 1236 411 3172017_c2_649 1088 17659 1026 341 361 −33 Enterobacter cloacae CONTIG388 GTC ORF with score 361 to: (ai:7000760185) (or:Pseudomonas aeruginosa) 22916653_c2_653 1089 17660 1974 657 467 −44 Enterobacter cloacae CONTIG388 GTC ORF with score 580 to: (ai:7501733302) (or:Klebsiella pneumoniae) 31916680_c2_656 1090 17661 3138 1045 732 −72 Klebsiella Contig244A GTC ORF with score 1073 to: pneumoniae (ai:7000821392) (or:Enterobacter cloacae) 10806888_c2_661 1091 17662 609 202 690 −69 Rickettsia AJ235269 Rickettsia prowazckii strain prowazekii Madrid E, complete genome. 29494376_c2_662 1092 17663 216 71 29812576_c2_663 1093 17664 924 307 1523 −156 Pseudomonas A53652 aeruginosa 13845836_c2_667 1094 17665 786 261 1268 −129 Pseudomonas P54292 (de:rhlr regulatory protein (elastase aeruginosa modulator)) 16285030_c2_669 1095 17666 270 89 405 −38 Pseudomonas A42325 aeruginosa 35784505_c2_670 1096 17667 840 279 1372 −140 Pseudomonas Q01269 (ec:4.2.1.51.4.—.—.—) aeruginosa (de:(ec4.2.1.51)/arogenate dehydratase,)) 35839660_c2_671 1097 17668 954 317 1428 −146 Pseudomonas AF054868 (de:pseudomonas aeruginosa aeruginosa autoinducer synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phec), hypothetical 0299 protein (yigm), chloramphenicol-sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete. . . 285416_c2_676 1098 17669 1350 449 36146025_c2_684 1099 17670 1002 333 135 −6 Klebsiella Contig544A GTC ORF with score 422 to: pneumoniae (ai:7000837913) (or:Enterobacter cloacae) 30167715_c2_690 1100 17671 1416 471 160 −8 Ruminococcus S21323 flavefaciens 7164581_c2_691 1101 17672 1062 353 118 −3 Acanthamoeba P10569 (sr:, amoeba) (de:myosin ic heavy castellanii chain) 36188266_c2_699 1102 17673 417 138 107 −5 Drosophila P48608 (sr:, fruit fly) (de:diaphanous protein) melanogaster 885452_c2_704 1103 17674 849 282 149 −10 Bacillus A69860 (cl:regulatory protein mpra) subtilis/Bacillus globigii 22058281_c2_706 1104 17675 714 237 99 −2 herpes simplex virus Z86099 (fn:immediate early protein; type 2 HSV-2 transcriptional) (de:herpes simplex virus type 2 (strain hg52), complete genome.) 25671927_c3_709 1105 17676 1068 355 123 −5 Caenorhabditis Z81518 (de:caenorhabditis elegans cosmid elegans f28d9, complete sequence.) (nt:cdna cst embl:c09269 comes from this gene; cdna est) 33439517_c3_717 1106 17677 537 178 139 −9 Orf virus B34768 11211567_c3_718 1107 17678 2610 869 1578 −162 Klebsiella Contig502A GTC ORF with score 1578 to: pneumoniae (ai:7000760254) (or:Pseudomonas aeruginosa) 10978785_c3_721 1108 17679 816 271 430 −41 Klebsiella Contig544A GTC ORF with score 488 to: pneumoniae (ai:7000788018) (or:Pseudomonas aeruginosa) 21890768_c3_722 1109 17680 783 260 258 −22 Enterobacter cloacae CONTIG420 GTC ORF with score 258 to: (ai:7000760258) (or:Pseudomonas aeruginosa) 20837933_c3_726 1110 17681 1695 564 114 −3 Strongylocentrotus L34680 (sr:strongylocentrotus purpuratus purpuratus (library: lambda gt11) gastrula stag) (de:strongylocentrotus purpuratus calcium-binding protein (endo16) mrna, complete cds.) 6719507_c3_733 1111 17682 1653 550 133 −4 equine herpesvirus AF030027 (fn:very large tegument protein) type 4 EHV-4 (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 35751086_c3_734 1112 17683 1458 485 14261280_c3_742 1113 17684 225 74 119 −7 Enterobacter cloacae CONTIG507 GTC ORF with score 150 to: (ai:7000772159) (or:Pseudomonas aeruginosa) 35597160_c3_744 1114 17685 768 255 149 −11 Klebsiella Contig398A GTC ORF with score 469 to: pneumoniae (ai:7000839977) (or:Enterobacter cloacae) 1270391_c3_755 1115 17686 702 233 123 −5 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithccine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 16844590_c3_756 1116 17687 1443 480 466 −44 Rhizobium sp. P55682 (sr:ngr234,) (de:hypothetical transport protein y4wd) 30721030_c3_764 1117 17688 261 86 101 −6 Enterobacter cloacae CONTIG507 GTC ORF with score 101 to: (ai:7000760300) (or:Pseudomonas aeruginosa) 15914591_c3_767 1118 17689 696 231 133 −7 mice|C57BL/6xCBA/ E29149 (cl:proline-rich protein) CaJ hybrid (sr:, house mouse) 35430201_c3_768 1119 17690 1176 391 162 −8 Ruminococcus S21323 flavefaciens 2628581_c3_770 1120 17691 1377 458 769 −76 Pseudomonas X99514 (fn:periplasmic link protein of aeruginosa multidrug efflux) (de:p. aeruginosa mexc, mexf & oprn genes.) 11039512_c3_786 1121 17692 657 218 133 −6 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 36035888_c3_787 1122 17693 1707 568 671 −66 Methanococcus Q58339 (ec:4.3.2.2) (de:adenylosuccinate jannaschii lyase, (adenylosuccinase) (asl)) 16895832_c3_792 1123 17694 684 227 130 −6 Homo sapiens X07884 (sr:human) (de:human mrna for alpha-1 (i) chain of procollagen type i.) (nt:preprocollagen (aa −22 to 450) (1500 is 1st base in) 12626002_c3_795 1124 17695 1533 510 171 −9 Nephila clavipes U37520 (de:nephila clavipes dragline silk protein spidroin 1 gene, partialcds.) 32697541_c3_796 1125 17696 648 215 157 −9 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b) 13026458_c3_797 1126 17697 543 180 235 −20 Klebsiella Contig311A GTC ORF with score 235 to: pneumoniae (ai:7000760333) (or:Pseudomonas aeruginosa) 32672881_c3_800 1127 17698 777 258 209 −16 Klebsiella Contig376A GTC ORF with score 550 to: pneumoniae (ai:7000762499) (or:Pseudomonas aeruginosa) 14148931_c3_801 1128 17699 1551 516 3261593_c3_805 1129 17700 648 215 123 −5 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase-binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein;) 7086058_c3_806 1130 17701 723 240 131 −6 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 35407691_c3_810 1131 17702 918 305 118 −4 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14152041_c3_814 1132 17703 432 143 144 −10 Klebsiella Contig534A GTC ORF with score 144 to: pneumoniae (ai:7000760350) (or:Pseudomonas aeruginosa) 35284757_c3_816 1133 17704 1203 400 95 −4 Klebsiella Contig396A GTC ORF with score 222 to: pneumoniae (ai:7000817275) (or:Enterobacter cloacae) 31297256_c3_817 1134 17705 1791 596 1813 −187 Escherichia coli P26616 (ec:1.1.1.38) (de:probable malate oxidoreductase (nad), (malic enzyme)) 16147543_c3_818 1135 17706 489 162 106 −6 Aspergillus Contig9437 GTC ORF with score 106 to: fumigatus (ai:7000760354) (or:Pseudomonas aeruginosa) 2525258_c3_826 1136 17707 1446 481 131 −5 Homo sapicns Z74616 (sr:human) (de:h. sapiens mrna for prepro-alpha2 (i) collagen.) 30260276_c3_827 1137 17708 1662 553 331 −30 Enterobacter cloacae CONTIG488 GTC ORF with score 618 to: (ai:7000806161) (or:Pseudomonas aeruginosa) 34198890_c3_828 1138 17709 1512 503 15839211_c3_832 1139 17710 1575 524 115 −3 Molluscum U60315 (de:molluscum contagiosum virus contagiosum virus subtype 1, complete genome.) subtype 1 (nt:contains large predicted non-globular regions and) 16035842_c3_835 1140 17711 1812 603 31385056_c3_837 1141 17712 486 161 144 −8 Oryctolagus P27884 (sr:, rabbit) (de:brain calcium channel cuniculus bi-2 protein) 13089652_c3_841 1142 17713 1467 488 30166407_f1_1 1143 17714 861 286 177 −14 Enterobacter cloacae CONTIG165 GTC ORF with score 216 to: (ai:7000773303) (or:Pseudomonas aeruginosa) 13086686_f1_4 1144 17715 948 315 871 −87 Bacillus E69902 subtilis/Bacillus globigii 11225693_f1_10 1145 17716 522 173 104 −3 Schizosaccharomyces Z98529 (sr:fission yeast) (de:s. pombe pombe chromosome i cosmid c16e8.) (nt:spac16c8.01, putative cytoskeleton assembly control) 12994581 _f1_16 1146 17717 390 129 106 −5 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 25910461_f1_24 1147 17718 2754 917 17047702_f1_33 1148 17719 2130 709 35255068_f1_36 1149 17720 453 150 174 −12 slime mold AF023910 (sr:slime mold) (de:physarum polycephalum dna topoisomerase i (top1) mrna, completecds.) 14745381_f1_47 1150 17721 444 147 34086637_f1_53 1151 17722 333 110 15103955_f1_54 1152 17723 2022 673 218 −15 Enterobacter cloacae CONTIG370 GTC ORF with score 322 to: (ai:7000807782) (or:Pseudomonas aeruginosa) 10321041_f1_60 1153 17724 444 147 96 −2 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 1370950_f1_64 1154 17725 513 170 155 −11 Klebsiella Contig560A GTC ORF with score 155 to: pneumoniae (ai:7000760442) (or:Pseudomonas aeruginosa) 2613152_f1_76 1155 17726 1551 516 315 −28 Rhodobacter AF010496 (de:rhodobacter capsulatus strain capsulatus sb1003, partial genome.) 12110458_f1_77 1156 17727 1326 441 699 −69 Bacillus H69784 subtilis/Bacillus globigii 31922906_f1_86 1157 17728 681 226 101 −2 Homo sapiens P18825 (sr:, human) (de:alpha-2c-1 adrenergic receptor (alpha-2c-1 adrenoceptor) (subtype c4)) 2864142_f1_88 1158 17729 987 328 163 −8 Alphaherpesvirus P11675 (sr:indiana-funkhauser/becker, prv) pseudorabies virus (de:immediate-early protein ie180) PRV 32523958_f1_90 1159 17730 1506 501 182 −10 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 22157016_f1_92 1160 17731 1980 659 122 −3 no gb taxonomy U52064 (de:kaposi's sarcoma-associated match herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 16878341 _f1_97 1161 17732 612 203 148 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33729206_f1_98 1162 17733 1089 362 320 −29 Pseudomonas AF061070 (de:pseudomonas stutzeri orf117 stutzeri (orf117), orf86 (orf86) genes, completecds; and ptxabcde operon, partial sequence.) (nt:putative binding protein component of) 16255455_f1_100 1163 17734 1746 581 409 −38 Pseudomonas AF061070 (de:pseudomonas stutzeri orf117 stutzeri (orf117), orf86 (orf86) genes, completecds; and ptxabcde operon, partial sequence.) (nt:putative inner membrane component of) 13020313_f1_101 1164 17735 852 283 11973916_f1_102 1165 17736 309 102 31929168_f1_103 1166 17737 2310 769 3161700_f1_105 1167 17738 1011 336 427 −40 Pseudomonas AJ007825 (de:pseudomonas aeruginosa mext aeruginosa gene.) 33726441_f1_108 1168 17739 900 299 14714580_f1_111 1169 17740 435 144 217 −17 Mycobacterium Z70283 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 98/162.) (nt:rv2214c, (mtcy190.25c),: 592.ephd, equivalent) 4422713_f1_112 1170 17741 897 298 598 −58 Mycobacterium AL008967 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 122/162.) (nt:rv2777c, (mtv002.42c), len: 356 aa. unknown) 12510938_f1_113 1171 17742 738 245 254 −22 Enterobacter cloacae CONTIG488 GTC ORF with score 254 to: (ai:7000760491) (or:Pseudomonas aeruginosa) 16274156_f1_116 1172 17743 1179 392 189 −14 Klebsiella Contig554A GTC ORF with score 211 to: pneumoniae (ai:7000780407) (or:Pseudomonas aeruginosa) 32598952_f1_117 1173 17744 930 309 133 −5 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hybrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 36189201_f1_119 1174 17745 876 291 153 −7 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 6072556_f1_120 1175 17746 1122 373 109 −2 Micrococcus luteus JQ0406 32520006_f1_124 1176 17747 2298 765 194 −11 Pseudomonas S53999 (cl:gramicidin s synthetase i repeat aeruginosa homology:acetate--coa ligase homology:acyl carrier protein homology) 21484761_f1_125 1177 17748 846 281 106 −2 Homo sapiens AF065164 (sr:human) (de:homo sapiens hyperpolarization activated channel 1 (ih 1) mrna, partial cds.) 31885430_f1_130 1178 17749 1650 549 90 −3 longfin squid S56117 (sr:, longfin squid) 12348841_f1_133 1179 17750 1308 435 653 −64 Streptomyces U09991 (fn:antibiotic efflux; transmembrane venezuelae protein) (de:streptomyces venezuelae isp5230 chloramphenicol resistance protein (cmlv) and chloramphenicol phosphotransferase genes, complete cds.) 36035202_f1_137 1180 17751 825 274 114 −4 Indian corn P14918 (sr:, maize) (de:extensin precursor (proline-rich glycoprotein)) 7286461_f1_142 1181 17752 1809 602 13016086_f1_146 1182 17753 1407 468 103 −2 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) georgiopolitanum dna) (de:pseudomonas sp. (strain imt37) monooxygenase subunit gene, completecds.) 16302018_f1_149 1183 17754 678 225 108 −6 Aspergillus Contig4037 GTC ORF with score 110 to: fumigatus (ai:187452) (or:Chironomus tentans) 24478803_f1_158 1184 17755 1230 409 16097557_f1_161 1185 17756 912 303 5113331_f1_168 1186 17757 1605 534 479 −45 Escherichia coli P00926 (ec:4.2.1.14) (de:d-serine dehydratase, (d-serine deaminase)) 3413533_f1_169 1187 17758 1080 359 363 −33 Streptomyces AL031124 (de:streptomyces coelicolor cosmid coelicolor 1c2.) (nt:sc1c2.12c, probable integral membrane protein,:) 35667691_f2_174 1188 17759 993 330 708 −70 Escherichia coli P36767 (de:hypothetical 34.0 kd protein in arom-araj intergenic region) 31882331_f2_176 1189 17760 261 86 116 −7 Enterobacter cloacae CONTIG432 GTC ORF with score 116 to: (ai:7000760554) (or:Pseudomonas aeruginosa) 21586443_f2_177 1190 17761 390 129 360 −33 Escherichia coli P30743 (de:surge protein) 31297691_f2_179 1191 17762 1698 565 95 −1 no gb taxonomy U52064 (de:kaposi's sarcoma-associated match herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 36383291_f2_180 1192 17763 2391 796 31911082_f2_185 1193 17764 3687 1228 196 −12 mice|C57BL/6xCBA/ A28996 (cl:proline-rich protein) (sr:, CaJ hybrid house mouse) 24098916_f2_187 1194 17765 519 172 96 −2 Schizosaccharomyces Z99161 (sr:fission yeast) (de:s. pombe pombe chromosome i cosmid c11g7.) (nt:spac11g7.01, unknown; serine rich, len:536aa) 10276416_f2_190 1195 17766 630 209 90 −2 Schizosaccharomyces D89103 (sr:schizosaccharomycepombe pombe (strain:pr745) cdna to mrna) (de:schizosaccharomycepombe mrna, partial cds, clone: sy 0143.) (nt:unnamed protein product) 10244467_f2_191 1196 17767 1335 444 107 −5 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna, cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) 20447153_f2_193 1197 17768 459 152 9978457_f2_195 1198 17769 1257 418 33681906_f2_211 1199 17770 414 137 124 −6 Bos primigenius P04258 (sr:, bovine) (de:collagen alpha 1 taurus (iii) chain) 32071055_f2_216 1200 17771 402 133 99 −5 Pisum sativum S57948 (sr:, garden pea) 12630032_f2_226 1201 17772 855 284 93 −2 Indian corn AF001635 (de:zea mays physical impedance induced protein (iig2) mrna, completecds.) (nt:contains a nuclear targeting sequence; the mrna was) 31330391_f2_227 1202 17773 1089 362 117 −7 Enterobacter cloacae CONTIG431 GTC ORF with score 406 to: (ai:7501741747) (or:Klebsiella pneumoniae) 30729155_f2_233 1203 17774 468 155 120 −6 Caenorhabditis AF000298 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 35757330_f2_236 1204 17775 1887 628 638 −63 Klebsiella Contig452A GTC ORF with score 975 to: pneumoniae (ai:7000824092) (or:Enterobacter cloacae) 25409665_f2_238 1205 17776 1737 578 594 −58 Klebsiella Contig452A GTC ORF with score 975 to: pneumoniae (ai:7000824092) (or:Enterobacter cloacae) 26666637_f2_239 1206 17777 990 329 184 −13 Archaeoglobus H69468 fulgidus 17038130_f2_241 1207 17778 327 108 107 −6 Ovis orientalis aries P26372 (sr:, sheep) (de:keratin, ultra high- sulfur matrix protein (uhs keratin)) 13141432_f2_242 1208 17779 1206 401 207 −16 Enterobacter cloacae CONTIG454 GTC ORF with score 229 to: (ai:7501747091) (or:Klebsiella pneumoniae) 21978957_f2_243 1209 17780 2100 699 110 −2 no gb taxonomy U93872 (sr:kaposi's sarcoma-associated match herpesvirus-human herpesvirus 8) (de:kaposi's sarcoma- associated herpesvirus glycoprotein m, dna replication protein, glycoprotein, dna replication protein, flieeinhibitory protein and y-cyclin genes . . . 16147688_f2_248 1210 17781 2985 994 1824 −188 Escherichia coli P23852 (de:rna polymerase associated protein (atp-dependent helicase hepa)) 14588291_f2_249 1211 17782 738 245 183 −14 Methanobacterium A69233 thermoautotrophicum 12791285_f2_251 1212 17783 276 91 106 −6 Enterobacter cloacae CONTIG363 GTC ORF with score 130 to: (ai:7000809218) (or:Pseudomonas aeruginosa) 16144716_f2_253 1213 17784 1383 460 35439566_f2_254 1214 17785 1266 421 139 −9 mice|C57BL/6xCBA/ M19419 (sr:mouse cdna to mrna, clone CaJ hybrid pump4) (de:mouse proline-rich salivary protein mrna, partial cds.) (nt:proline-rich salivary protein) 29975830_f2_256 1215 17786 573 190 123 −5 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 25495392_f2_258 1216 17787 1632 543 333 −30 Pseudomonas AF061267 (de:pseudomonas stutzeri putative stutzeri alpha-ketoglutarate- dependenthypophosphite dioxygenase (htxa), binding protein component htxb (htxb), inner membrane component htxc (htxc), atpase component htxd (htxd), inner membrane component htxc ( . . . 32557793_f2_264 1217 17788 345 114 164 −12 Mycobacterium Q04001 (de:mtp40 antigen protein) tuberculosis 25808576_f2_274 1218 17789 1113 370 147 −7 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′ region of gyra and gyrb (orf 3)) 19739561_f2_279 1219 17790 6858 2285 2109 −217 Bacillus D69681 (cl:surfactin synthetase:acetate--coa subtilis/Bacillus ligase homology:acyl carrier protein globigii homology:gramicidin s synthetase i repeat homology) 13098967_f2_280 1220 17791 1572 523 387 −36 Bordetella pertussis AF006000 (de:bordetella pertussis d-3- phosphoglycerate dehydrogenase homolog (scra) and brg1 (brg1) genes, complete cds.) (nt:orf4; similar to salicylate hydroxylase) 9876082_f2_284 1221 17792 1089 362 440 −41 mice|C57BL/6xCBA/ AF013288 (fn:oxidizes 9-cis retinol into 9-cis CaJ hybrid retinaldehyde) (sr:house mouse) (ec:1.1.1.105) (de:mus musculus 9-cis retinol dehydrogenase (rdh4) mrna, complete cds.) (nt:membrane bound enzyme) 25507705_f2_285 1222 17793 1671 556 243 −20 Bacillus G69795 subtilis/Bacillus globigii 32525283_f2_286 1223 17794 996 331 827 −82 Streptomyces AL021409 (pn:3-oxoacyl-(acyl-carrier-protein) coelicolor synthase) (de:streptomyces coelicolor cosmid 3f7.) (nt:sc3f7.08, probable 3-oxoacyl-(acyl-carrier-protein)) 29871083_f2_289 1224 17795 1086 361 371 −34 Klebsiella Contig555A GTC ORF with score 405 to: pneumoniae (ai:7000828165) (or:Enterobacter cloacae) 21485206_f2_291 1225 17796 1257 418 161 −9 mice|C57BL/6xCBA/ S19560 (cl:proline-rich protein) (sr:, house CaJ hybrid mouse) 12969501_f2_292 1226 17797 1458 485 175 −10 Microbacterium X79027 (de:m. ammoniaphilum genes mamir ammoniaphilum and mamim.) 13025702_f2_293 1227 17798 426 141 134 −7 Chinese oak AF083334 (sr:chinese oak silkmoth) silkmoth (de:antheraea pernyi fibroin gene, complete cds.) 3385441_f2_304 1228 17799 1701 566 385 −36 Klebsiella Contig534A GTC ORF with score 519 to: pneumoniae (ai:7000828790) (or:Enterobacter cloacae) 9800706_f2_311 1229 17800 345 114 94 −4 Arabidopsis thaliana AC000098 (sr:thale cress) (de:arabidopsis thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts 1136 comes from this gene.) 11855091_f2_327 1230 17801 855 284 977 −98 Escherichia coli P00926 (ec:4.2.1.14) (de:d-serine dehydratase, (d-serine deaminase)) 24713131_f3_335 1231 17802 1077 358 102 −2 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 29806652_f3_336 1232 17803 336 111 359 −33 Pseudomonas P95459 (de:major cold shock protein cspa) aeruginosa 24614408_f3_344 1233 17804 465 154 98 −2 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b) 10995332_f3_346 1234 17805 4266 1421 642 −61 Paracoccus AJ223460 (de:paracoccus denitrificans flhs, denitrificans flhr, abca, abcb, abcc, pqqe genesand orf's.) 12985053_f3_352 1235 17806 441 146 127 −7 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus CaJ hyhrid plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 26032708_f3_354 1236 17807 468 155 122 −6 Burkholderia U41162 (sr:burkholderia cepacia cepacia strain=17616) (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 16036062_f3_366 1237 17808 1452 483 11775817_f3_377 1238 17809 1038 345 220 −18 Pseudomonas U59457 (de:pseudomonas aeruginosa ankyrin aeruginosa (ankb) gene, complete cds.) (nt:ankyrin) 9785968_f3_379 1239 17810 1410 469 33629040_f3_384 1240 17811 303 100 35659656_f3_386 1241 17812 504 167 119 −6 Caenorhabditis Z82268 (de:caenorhabditis elegans cosmid elegans f52b11, complete sequence.) (nt:predicted using genefinder; cdna est embl:d65629) 33458531_f3_389 1242 17813 1875 624 26666286_f3_390 1243 17814 1491 496 1740 −179 Serratia marcescens P19147 (ec:3.1.3.1) (de:alkaline phosphatase precursor, (apase)) 24786080_f3_391 1244 17815 4179 1392 403 −36 Enterobacter cloacae CONTIG513 GTC ORF with score 445 to: (ai:7501799795) (or:Klebsiella pneumoniae) 29969705_f3_403 1245 17816 630 209 112 −4 Homo sapiens I78877 (cl:fos/jun dna-binding domain homology) (sr:, man) 2870331_f3_404 1246 17817 1419 472 103 −2 Gallus gallus Y14166 (sr:chicken) (de:gallus gallus mrna domesticus for attachment region binding protein (arbp).) 29863965_f3_406 1247 17818 546 181 146 −9 Homo sapiens PN0099 (sr:, man) 4427162_f3_408 1248 17819 696 231 158 −9 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain (type 6/strain uganda-1102) ie2hom mrna, Uganda-1102) complete cds.) (nt:similar to the immediate-early 2 protein of human) 24729717_f3_415 1249 17820 588 195 119 −4 human herpesvirus U13194 (fn:transcriptional regulation) type 6 HRV-6 (de:human herpesvirus 6 replication origin-binding protein (hdrfo), partial cds, helicase-primase component (hdrf1), virion protein (hdlf1), putative helicase (hdrf2), putative phosphoprotein(cdrf1), replica . . . 12634542_f3_418 1250 17821 336 111 112 −7 Aspergillus Contig5670 GTC ORF with score 206 to: fumigatus (ai:380588) (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 34503292_f3_425 1251 17822 2418 805 820 −82 Cyanobacterium S74707 (cl:response regulator homology) synechocystis (sr:pcc 6803,, pcc 6803) (sr:pcc 6803,) 25803768_f3_426 1252 17823 558 185 96 −3 Klebsiella Contig548A GTC ORF with score 443 to: pneumoniae (ai:7000843295) (or:Enterobacter cloacae) 2946032_f3_428 1253 17824 1674 557 370 −34 Pseudomonas AF061070 (de:pseudomonas stutzeri orf117 stutzeri (orf117), orf86 (orf86) genes, completecds; and ptxabcde operon, partial sequence.) (nt:putative atpase component of) 32526906_f3_429 1254 17825 330 109 97 −4 mice|C57BL/6xCBA/ U95016 (sr:house mouse) (de:mus musculus CaJ hybrid myocyte nuclear factor-beta (mnf-b) mrna, completecds.) (nt:hnf-3/forkhead, aminoacids 279..389: winged helix) 29766658_f3_430 1255 17826 1257 418 133 −5 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 16145283_f3_432 1256 17827 513 170 12969586_f3_437 1257 17828 582 193 103 −2 Molluscum U60315 (de:molluscum contagiosum virus contagiosum virus subtype 1, complete genome.) subtype 1 (nt:contains large predicted non-globular regions and) 20807131_f3_438 1258 17829 1173 390 192 −13 Achromobacter A61183 georgiopolitanum 32517881_f3_441 1259 17830 2409 802 842 −84 Mycobacterium Z98741 (de:mycobacterium leprae cosmid leprae b22.) (nt:mlcb22.16c, possible oxidoreductase, len: 596 aa;) 12989566_f3_442 1260 17831 852 283 111 −3 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 35753537_f3_445 1261 17832 564 187 132 −6 equine herpesvirus P28968 (sr:ab4p,chv-1) (de:glycoprotein x type 1 EVH-1 precursor) 31760458_f3_457 1262 17833 471 156 145 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29870917_f3_458 1263 17834 1260 419 450 −42 Bacillus Z82015 (de:b. subtilis yuk(a,b,c,d,e,f), subtilis/Bacillus yuk(i,j,k,l,m) and ald genes.) globigii 26738131_f3_461 1264 17835 801 266 181 −12 Burkholderia U41162 (sr:burkholderia cepacia cepacia strain=17616) (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 30369705_f3_464 1265 17836 1314 437 866 −86 Saccharopolyspora P33271 (sr:, streptomyces erythracus) erythraca (ec:1.14.—.—) (de:cytochrome p450 107b1, (p450cviib1)) 9895706_f3_466 1266 17837 615 204 179 −12 Caenorhabditis U80846 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 31308506_f3_468 1267 17838 306 101 97 −5 Streptomyces AF058302 (de:streptomyces roseofulvus roseofulvus frenolicin biosynthetic gene cluster, complete sequence.) (nt:frnj; second acp for putative starter unit) 14713918_f3_469 1268 17839 870 289 6301028_f3_470 1269 17840 1050 349 99 −4 Lycopersicon S14977 (sr:, tomato) esculentum 17046941_f3_474 1270 17841 2280 759 316 −44 Bacillus H69874 subtilis/Bacillus globigii 34239518_f3_476 1271 17842 1035 344 201 −12 equine herpesvirus AF030027 (fn:very large tegument protein) type 4 EHV-4 (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 6376592_f3_478 1272 17843 486 161 110 −4 Bos primigenius P02453 (sr:, bovine) (de:collagen alpha 1(i) taurus chain (fragments)) 16532006_f3_488 1273 17844 1839 612 24314076_f3_493 1274 17845 852 283 220 −18 Vibrio U51896 (sr:vibrio parahaemolyticus parahacmolyticus strain=bb22) (de:vibrio parahaemolyticus lateral flagellar lafx locus: lfgn gene, partial cds, lfgm, lfga, lfgb, lfgc, and lfgd genes, complete cds,and lfge gene, partial cds.) (nt:potential lateral flagellar p . . . 32230382_f3_494 1275 17846 417 138 13097632_f3_495 1276 17847 486 161 12133331_f3_496 1277 17848 489 162 107 −3 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 14704791_f3_497 1278 17849 627 208 163 −11 mice|C57BL/6xCBA/ A28996 (cl:proline-rich protein) (sr:, house CaJ hybrid mouse) 16281636_f3_499 1279 17850 2571 856 95 −1 Drosophila Q24266 (sr:, fruit fly) (de:transcription factor melanogaster btd buttonhead)) 525033_f3_500 1280 17851 573 190 106 −3 Orf virus B34768 34620716_f3_502 1281 17852 609 202 192 −14 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4859705_f3_504 1282 17853 483 161 180 −14 Plasmid pAH4 JC2320 10004030_c1_506 1283 17854 1023 340 164 −9 Canadian hard P10388 (sr:, wheat) (de:glutenin, high winter wheat molecular weight subunit dx5 precursor) 20839205_c1_508 1284 17855 672 223 234 −20 Enterobacter cloacae CONTIG500 GTC ORF with score 234 to: (ai:7000760886) (or:Pseudomonas aeruginosa) 4939067_c1_510 1285 17856 2538 845 199 −12 Micrococcus luteus JQ0405 6071058_c1_512 1286 17857 627 208 209 −17 Cyanobacterium S75866 (sr:pcc 6803,, pcc 6803) synechocystis (sr:pcc 6803,) 36052081_c1_515 1287 17858 1092 363 358 −33 Helicobacter pylori JHP17 (de:regulatory functi:chemotaxis and motil:chemotaxis protein) (sr:strain j99) 31258540_c1_516 1288 17859 1431 476 22944215_c1_519 1289 17860 390 129 111 −5 Cyanobacterium S75142 (sr:pcc 6803,, pcc 6803) synechocystis (sr:pcc 6803,) 11774040_c1_524 1290 17861 432 143 96 −5 Klebsiella Contig512A GTC ORF with score 96 to: pneumoniae (ai:7000760902) (or:Pseudomonas aeruginosa) 22735141_c1_528 1291 17862 1218 405 364 −33 Cyanobacterium S74653 (cl:response regulator homology) synechocystis (sr:pcc 6803,, pcc 6803) (sr:pcc 6803,) 25995826_c1_529 1292 17863 1125 374 398 −37 Acinetobacter CONTIG134 GTC ORF with score 398 to: baumannii C (ai:7000760907) (or:Pseudomonas aeruginosa) 4892180_c1_530 1293 17864 465 154 250 −21 Salmonella P40676 (de:transcriptional regulator slya (salmolysin) choleraesuis (cytolysin slya)) serotype typhimurium 26211016_c1_531 1294 17865 2112 703 476 −70 Pseudomonas U93274 (de:pseudomonas aeruginosa yafe (yafe), lcub aeruginosa (lcub), asd (asd), fimv (fimv), and hist (hist) genes, complete cds; trpf (trpf) gene, partial cds: and unknown gene.) 10047830_c1_532 1295 17866 408 135 94 −4 common tobacco PQ0475 (sr:, common tobacco) 4504158_c1_534 1296 17867 300 99 307 −28 Klebsiella Contig485A GTC ORF with score 307 to: pneumoniae (ai:7000760912) or:Pseudomonas aeruginosa) 11771077_c1_538 1297 17868 864 287 181 −14 Klebsiella Contig374A GTC ORF with score 217 to: pneumoniae (ai:7000782681) (or:Pseudomonas aeruginosa) 14978443_c1_548 1298 17869 1869 622 16658465_c1_553 1299 17870 462 153 119 −6 Plasmodium P08672 (sr:berok,) (de:circumsporozoite cynomolgi protein precursor (cs)) 31886583_c1_554 1300 17871 513 170 112 −4 human herpesvirus U92288 (fn:helicase, helicase-primase type 6 HHV-6 complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie-b) 12942826_c1_563 1301 17872 414 137 105 −5 Dictyostelium P14328 (sr:, slime mold) (de:spore coat discoideum protein sp96) 104667_c1_566 1302 17873 753 250 475 −45 Paracoccus P54414 (ec:3.4.21.92) denitrificans (de:(endopeptidase clp)) 36580141_c1_579 1303 17874 2178 725 3699 −9999 Pseudomonas P15713 (cc:3.1.4.3) (de:(phosphatidylcholine aeruginosa cholinephosphohydrolase 15636336_c1_582 1304 17875 1098 365 107 −2 Caenorhabditis Z68011 (de:caenorhabditis elegans cosmid elegans t21b6, complete sequence.) (nt:similarity to xenopus f- spondin precursor (pir acc.) 11849135_c1_587 1305 17876 1032 343 105 −2 Pseudomonas ZS4213 (de:p. aeruginosa algy gene.) aeruginosa 16306892_c1_591 1306 17877 1716 571 1154 −117 Salmonella P36555 (de:hypothetical 61.6 kd protein in choleraesuis bass/pmra-adiy intergenic region) serotype typhimurium 10036333_c1_598 1307 17878 900 299 108 −3 Gallus gallus K02113 (sr:chicken) (de:gallus gallus domesticus vitellogenin gene coding for phosvitin, exons 23 and 24.) 16145337_c1_600 1308 17879 375 124 35785280_c1_607 1309 17880 462 153 11069581_c1_610 1310 17881 1164 387 188 −11 Canadian hard S02262 (cl:glutenin) (sr:, common wheat) winter wheat 1969681_c1_617 1311 17882 1275 424 161 −9 Plasmodium vivax P13826 (sr:sal-i,) (de:circumsporozoite protein (cs) (fragment)) 32291703_c1_620 1312 17883 1215 404 32283518_c1_621 1313 17884 1089 362 171 −10 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid elegans c18h7.) (nt:similar to cuticular collagen; c18h7.3) 36038191 _c1_622 1314 17885 525 174 267 −23 Klebsiella Contig462A GTC ORF with score 267 to: pneumoniae (ai:7000761000) (or:Pseudomonas aeruginosa) 26041386_c1_624 1315 17886 3084 1027 465 −41 Escherichia coli AF044499 (de:escherichia coli strain ec50 rhse accessory genetic element vgreprotein, core protein, and dsorf-e5 genes, complete cds.) 32710801_c1_631 1316 17887 1431 476 189 −12 Plasmodium P08675 (sr:london,) (de:circumsporozoite cynomolgi protein precursor (cs)) 20594505_c1_638 1317 17888 336 111 24354503_c1_639 1318 17889 432 143 162 −12 Haemophilus P44269 (de:hypothetical protein hi1601 influenzae precursor) 34650168_c1_640 1319 17890 873 290 504 −48 Haemophilus P44268 (de:hypothetical protein hi1600) influenzae 2473783_c1_648 1320 17891 1512 503 2296 −238 Pseudomonas P05695 (de:porin p precursor (outer aeruginosa membrane protein d1)) 17047918_c1_649 1321 17892 468 155 12589126_c1_650 1322 17893 564 187 10728808_c1_652 1323 17894 771 256 14960140_c1_656 1324 17895 3540 1179 1177 −119 Streptomyces AL031031 (de:streptomyces coelicolor cosmid coelicolor 7c7.) (nt:sc7c7.16c, probable atp dependent dna helicase,) 13130417_c1_658 1325 17896 549 182 131 −6 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early pseudorabies virus protein ie175) PRV 35432208_c1_668 1326 17897 504 167 181 −14 Homo sapiens S53363 (sr:, man) (mp: 11p15.5-11p15.5) 21580143_c1_672 1327 17898 1719 572 143 −6 Canadian hard P10388 (sr:, wheat) (de:glutenin, high winter wheat molecular weight subunit dx5 precursor) 4775_c1_674 1328 17899 972 323 474 −45 Aeronionas U56832 (fn:converts prolyl-imidic bonds from hydrophila cis to trans) (cc:5.2.1.8) (de:aeromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf3; immunonphilin: peptidyl prolyl isomerase:) 14949042_c2_677 1329 17900 906 301 97 −2 Pseudomonas S29309 aeruginosa 14878563_c2_681 1330 17901 1350 449 1112 −113 Pseudomonas putida M57613 (sr:pseudomonas putida (strain ppg2) dna) (de:pseudomonas putida branched-chain keto acid dehydrogenase operon (bkda1, bkda1 and bkda2), transacylase e2 (bkdb), bkdr andlipoamide dehydrogenase (lpdv) genes, complete cds.) (nt:orf) 14111281_c2_682 1331 17902 1467 488 429 −40 Escherichia coli P21503 (de:hypothetical 41.4 kd protein in dmsc-pfla intergenic region (orf y)) 7120942_c2_687 1332 17903 996 331 1395 −143 Pseudomonas AB012768 (fn:methyltransferase) aeruginosa (sr:pseudomonas aeruginosa (str:pao1) dna) (de:pseudomonas aeruginosa gene for cher, complete cds.) (nt:cher is involved in methylation of transducer) 10816306_c2_689 1333 17904 1980 659 236 −18 Rickettsia AJ235269 Rickettsia prowazekii strain prowazekii Madrid E, complete genome. 31379165_c2_691 1334 17905 471 156 177 −14 Klebsiella Contig534A GTC ORF with score 177 to: pneumoniae (ai:7000761069) (or:Pseudomonas aeruginosa) 1270318_c2_693 1335 17906 1059 352 157 −8 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid elegans c18h7.) (nt:similar to cuticular collagen; c18h7.3) 2938330_c2_706 1336 17907 2616 871 123 −4 Chlamydomonas 550754 eugametos 22135141_c2_708 1337 17908 666 221 102 −2 cabbage looper AF000605 (sr:cabbage looper) (de:trichoplusia ni insect intestinal mucin iiml4 mrna, complete cds.) 11194792_c2_715 1338 17909 1482 493 9875828_c2_717 1339 17910 1230 409 123 −4 Homo sapiens X63071 (sr:human) (de:h. sapiens mrna for novel dna binding protein.) 36016316_c2_720 1340 17911 1209 402 12007052_c2_724 1341 17912 204 67 96 −5 Enterobacter cloacae CONTIG419 GTC ORF with score 105 to: (ai:7000763709) (or:Pseudomonas aeruginosa) 14961393_c2_725 1342 17913 543 180 103 −4 Persian tobacco JQ1686 (sr:, persian tobacco) 16541392_c2_726 1343 17914 402 133 101 −5 longfin squid S56117 (sr:, longfin squid) 36579131_c2_728 1344 17915 717 238 128 −5 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early pseudorabies virus protein ie175) PRV 35755125_c2_734 1345 17916 1491 496 4401915_c2_736 1346 17917 1167 388 150 −7 Arancus diadematus U47855 (de:arancus diadematus fibroin-3 (adf-3) mrna, partial cds.) 29710936_c2_739 1347 17918 501 166 113 −7 Escherichia coli P76111 (de:hypothetical 15.9 kd protein in tchb-ansp intergenic region) 14730290_c2_740 1348 17919 432 143 154 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14556881_c2_742 1349 17920 282 93 106 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16142208_c2_745 1350 17921 396 131 108 −6 Orf virus D34768 17004708_c2_746 1351 17922 417 138 113 −6 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 16926965_c2_752 1352 17923 993 330 469 −44 Escherichia coli P23523 (de:hypothetical 31.0 kd protein in rnpb-soha intergenic region (orf 2)) 2631907_c2_753 1353 17924 2262 753 110 −2 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 31742765_c2_770 1354 17925 1098 365 150 −7 Nephila clavipes A36068 12507328_c2_772 1355 17926 1311 436 156 −8 Nephila clavipes A44112 14708457_c2_776 1356 17927 711 237 131 −6 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 32243877_c2_777 1357 17928 849 282 107 −2 mice|C57BL/6xCBA/ U32107 (sr:house mouse) (de:mus musculus CaJ hybrid type vii collagen (col7a1) mrna, complete cds.) 21688516_c2_778 1358 17929 795 264 92 −4 Klebsiella Contig452A GTC ORF with score 223 to: pneumoniae (ai:7000824048) (or:Enterobacter cloacae) 5275458_c2_779 1359 17930 1599 532 194 −12 Microbacterium X79027 (de:m. ammoniaphilum genes mamir ammoniaphilum and mamim.) 31844561_c2_780 1360 17931 459 152 22082202_c2_781 1361 17932 3981 1326 2580 −268 Haemophilus P45018 (de:atp-dependent helicase hrpa influenzae homolog) 16277187_c2_782 1362 17933 1551 516 112 −2 Mycobacterium AL022022 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 148/162.) (nt:rv3508, (mtv023.15), len: 1901. member of) 9781311_c2_783 1363 17934 546 181 255 −22 Bacillus O07513 (de:hit protein) subtilis/Bacillus globigii 31677141_c2_784 1364 17935 1239 412 248 −18 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) 35213556_c2_785 1365 17936 408 135 127 −7 Litomosoides U54556 (de:litomosoides sigmodontis sigmodontis microfilarial sheath proteins shp3a (shp3a) and shp3 (shp3) genes, complete cds.) (nt:structural protein; similar to shp3 genes from) 35363176_c2_791 1366 17937 2712 903 16017781_c2_793 1367 17938 549 182 26455383_c2_796 1368 17939 792 263 103 −5 Klebsiella Contig545A GTC ORF with score 138 to: pneumoniae (ai:7000757952) (or:Pseudomonas aeruginosa) 6290807_c2_798 1369 17940 621 206 225 −19 Escherichia coli P34086 (de:rna polymerase sigma-e factor (sigma-24)) 4145958_c2_802 1370 17941 1413 470 120 −4 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 12268763_c2_803 1371 17942 1563 520 2303 −239 Pseudomonas P32977 (de:porin o precursor) aeruginosa 16150642_c2_807 1372 17943 807 268 233 −18 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hhl) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for membrane glcoprotein complete cds. 22783541_c2_813 1373 17944 633 210 101 −3 Azospirillum P25315 (de:nify protein) brasilense 14113530_c2_822 1374 17945 3402 1133 115 −3 Klebsiella Contig560A GTC ORF with score 189 to: pneumoniae (ai:7000777501) (or:Pseudomonas aeruginosa) 35572677_c2_826 1375 17946 1827 608 33786581_c2_833 1376 17947 891 296 128 −5 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hhl) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for membrane glycoprotein complete cds.) 1424025_c2_835 1377 17948 246 81 94 −5 Enterobacter cloacae CONTIG305 GTC ORF with score 101 to: (ai:91365) (or:Porphyromonas gingivalis) (sr:, bacteroides gingivalis) (ec:3.4.22.—) (de:protease prth,) 4861027_c3_838 1378 17949 201 66 134 −8 Enterobacter cloacae CONTIG412 GTC ORF with score 1554 to: (ai:7501795377) (or:Klebsiella pneumoniae) 32672967_c3_840 1379 17950 1158 385 279 −25 Enterobacter cloacae CONTIG500 GTC ORF with score 279 to: (ai:7000761218) (or:Pseudomonas aeruginosa) 32692207_c3_847 1380 17951 831 276 165 −9 Alphaherpesvirus B40505 pseudorabies virus PRV 34474081_c3_854 1381 17952 909 302 130 −6 mice|C57BL/6xCBA/ S19560 (cl:proline-rich protein) (sr:, house CaJ hybrid mouse) 35236330_c3_859 1382 17953 2550 849 1412 −144 Escherichia coli M30198 (sr:escherichia coli (strain k-12) dna) (de:e. coli recq gene complete cds, and plda gene, 3′ end.) 12992632_c3_865 1383 17954 468 155 130 −7 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 31927040_c3_867 1384 17955 555 184 147 −9 Epstein-Barr virus P03181 (sr:b95-8, human herpesvirus 4) (de:hypothetical bhlf1 protein) 22355131_c3_874 1385 17956 1119 372 954 −96 Neisseria L07845 (fn:d to 1 conversion of the glycero gonorrhoeae moiety of the) (sr:neisseria gonorrhoeae (strain ms11b2) dna) (de:neisseria gonorrhoeae ribokinase (rbk) gene, 3′ end; adp-1-glycero-d- mannoheptose epimerase (gme) gene, complete cds.) 35676591_c3_880 1386 17957 1917 638 138 −5 Nephila clavipes A36068 33838542_c3_883 1387 17958 1083 360 158 −10 Klebsiella Contig487A GTC ORF with score 470 to: pneumoniae (ai:7000825199) (or:Enterobacter cloacae) 35806955_c3_887 1388 17959 2484 827 258 −19 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 1199156_c3_888 1389 17960 1110 369 237 −18 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 35754151_c3_889 1390 17961 870 289 171 −10 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 4379155_c3_900 1391 17962 822 273 99 −5 Archaeoglobus A69334 (cl:transcriptional repressor glnr) fulgidus 36072892_c3_902 1392 17963 573 190 140 −8 Homo sapiens O00268 (sr:, human) (de:(tafii135) (tafii-130) 11142881_c3_904 1393 17964 783 260 105 −3 Homo sapiens Q15427 (sr:, human) (de:spliceosome associated protein 49 (sap 49) (s(3b53)) 25519776_c3_905 1394 17965 1401 466 12368955_c3_924 1395 17966 1788 595 34257887_c3_926 1396 17967 2667 888 1056 −107 Enterobacter cloacae CONTIG499 GTC ORF with score 1793 to: (ai:7501787714) (or:Klebsiella pneumoniae) 36614816_c3_929 1397 17968 726 241 359 −33 Acinetobacter CONTIG211 GTC ORF with score 359 to: baumannii C (ai:7000761307) (or:Pseudomonas aeruginosa) 22683385_c3_931 1398 17969 2067 688 427 −38 Escherichia coli P46481 (de:hypothetical 73.6 kd protein in argr-cafa intergenic region (f655)) 36349152_c3_932 1399 17970 1074 357 593 −58 Escherichia coli P46482 (de:hypothetical 34.8 kd protein in argr-cafa intergenic region) 25492077_c3_938 1400 17971 1689 562 1569 −161 Escherichia coli P29212 (ec:6.2.1.3) (de:synthetase)) 9901963_c3_939 1401 17972 170I 566 1625 −167 Escherichia coli P29212 (ec:6.2.1.3) (de:synthetase)) 29791656_c3_955 1402 17973 696 231 124 −5 Arabidopsis thaliana AC000098 (sr:thale cress) (de:arabidopsis thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts1136 comes from this gene.) 34650655_c3_956 1403 17974 267 88 106 −5 Litomosoides U54556 (de:litomosoides sigmodontis sigmodontis microfilarial sheath proteins shp3a (shp3a) and shp3 (shp3) genes, complete cds.) (nt:structural protein; similar to shp3 genes from) 9895930_c3_957 1404 17975 930 309 93 −1 Aeromonas sp. I39540 (ec:3.2.1.14) 16541008_c3_959 1405 17976 846 281 127 −5 Caenorhabditis U41557 (sr:caenorhabditis elegans elegans strain=bristol n2) (de:caenorhabditis elegans cosmid c50f7.) (nt:histidine-rich) 21967_c3_961 1406 17977 579 192 29807330_c3_970 1407 17978 423 140 98 −3 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hhl) type 1 EVH-1 dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 35679831_c3_972 1408 17979 1476 491 280 −24 Haemophilus P43711 (ec:2.3.1.41) (de:ketoacyl-acp influenzae synthase iii) (kas iii)) 15741667_c3_980 1409 17980 765 254 16307956_c3_990 1410 17981 879 292 354 −32 Mycobacterium AL022004 (de:mycobacterium tuberculosis tuberculosis h37rv complete genome; segment 40/162.) (nt:rv0851c, (mtv043.44c), len: 275. unknown) 2204527_c3_991 1411 17982 738 245 206 −17 Bacillus O31553 (de:hypothetical 11.9 kd protein in subtilis/Bacillus acor-glva intergenic region) globigii 35801028_c3_994 1412 17983 1782 593 598 −57 Streptomyces AL031031 (de:streptomyces coelicolor cosmid coelicolor 7c7.) (nt:sc7c7.16c, probable atp dependent dna helicase,) 22469793_c3_998 1413 17984 1662 553 305 −24 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 34636090_c3_1007 1414 17985 609 202 289 −25 Myxococcus xanthus U81516 (de:myxococcus xanthus abc transporter homolog gene, partial cds and rna polymerase sigma-54 factor (rpon) gene, complete cds.) (nt:orf: 3′ of rpon) 31652042_c3_1008 1415 17986 921 306 479 −45 Streptomyces AL031031 (de:streptomyces coelicolor cosmid coelicolor 7c7.) (nt;sc7c7.17, possible transcriptional regulatory) 14089028_c3_1009 1416 17987 2262 753 1264 −129 Escherichia coli P13036 (de:iron (iii) dicitrate transport protein feca precursor) 469841_c3_1010 1417 17988 1890 629 860 −87 Rickettsia AJ235269 Rickettsia prowazekii strain prowazekii Madrid E, complete genome. 10442816_c3_1012 1418 17989 1212 403 141 −9 Enterobacter cloacae CONTIG480 GTC ORF with score 141 to: (ai:7000761390) (or:Pseudomonas aeruginosa) 3260043_f1_5 1419 17990 1056 351 143 −6 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain (type 6/strain uganda-1102) ie2hom mrna, Uganda-1102) complete cds.) (nt:similar to the immediate-early 2 protein of human) 31492917_f1_19 1420 17991 1572 523 9791566_f1 _22 1421 17992 426 141 106 −6 Candida albicans CONTIG525 GTC ORF with score 106 to: 3 (ai:7000761414) (or:Pseudomonas aeruginosa) 10800066_f1_32 1422 17993 1266 421 130 −6 Klebsiella Contig275A GTC ORF with score 199 to: pneumoniae (ai:7000843618) (or:Enterobacter cloacae) 6308563_f1_46 1423 17994 573 190 91 −4 Klebsiella Contig536A GTC ORF with score 91 to: pneumoniae (ai:7000761438) (or:Pseudomonas aeruginosa) 22520300_f1_60 1424 17995 828 275 99 −5 Klebsiella Contig421A GTC ORF with score 177 to: pneumoniae (ai:7000821620) (or:Enterobacter cloacae) 20206455_f1_67 1425 17996 1356 451 163 −8 no gb taxonomy U93872 (sr:kaposi's sarcoma-associated match herpesvirus- human herpesvirus 8) (de:kaposi's sarcoma-associated herpesvirus glycoprotein m, dna replication protein, glycoprotein, dna replication protein, fliceinhibitory protein and y-cyclin genes . . . 26307665_f1_72 1426 17997 510 169 175 −13 Klebsiella Contig551A GTC ORF with score 217 to: pneumoniae (ai:7000761465) (or:Pseudomonas aeruginosa) 413966_f1_73 1427 17998 720 239 217 −18 Klebsiella Contig551A GTC ORF with score 217 to: pneumoniae (ai:7000761465) (or:Pseudomonas aeruginosa) 7160200_f1_75 1428 17999 1260 419 1269150_f1_82 1429 18000 1896 631 16300711_f1_84 1430 18001 3843 1280 120 −4 Sus scrofa domestica S55316 (sr:, domestic pig) 10167086_f1_85 1431 18002 612 203 100 −2 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) discoideum dna) (de:dictyostelium discoideum gene for trfa, complete cds.) 22757216_f1_88 1432 18003 1398 465 2135841_f1_90 1433 18004 1230 409 23837791_f1_93 1434 18005 1437 478 34570187_f1_94 1435 18006 831 276 204 −17 Klebsiella Contig550A GTC ORF with score 714 to: pneumoniae (ai:7000838996) (or:Enterobacter cloacae) 12141657_f1_95 1436 18007 990 329 198 −15 Klebsiella Contig534A GTC ORF with score 278 to: pneumoniae (ai:7000828862) (or:Enterobacter cloacae) 2383561_f1_96 1437 18008 1302 433 145 −7 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 30332817_f1_102 1438 18009 1770 589 512 −49 Klebsiella Contig218A GTC ORF with score 664 to: pneumoniae (ai:7000815432) (or:Enterobacter cloacae) 15832250_f1_103 1439 18010 978 325 350 −32 Escherichia coli F65039 472965_f1_104 1440 18011 1305 434 840 −84 Escherichia coli D90888 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #438(58.9—59.3 min.).) (nt:similar to (swissprot accession number p37908)) 31925681_f1_106 1441 18012 636 211 418 −39 Escherichia coli P37643 (de:region (o440)) 31673916_f1_110 1442 18013 1104 367 543 −53 Klebsiella Contig460A GTC ORF with score 543 to: pneumoniae (ai:7000761502) (or:Pseudomonas aeruginosa) 12995755_f1_111 1443 18014 666 221 159 −11 Klebsiella Contig560A GTC ORF with score 565 to: pneumoniae (ai:7000846961) (or:Enterobacter cloacae) 16507340_f1_113 1444 18015 798 265 372 −34 Arabidopsis thaliana U90439 (sr:thale cress) (de:arabidopsis thaliana chromosome ii bac t06d20 genomic sequence, complete sequence.) (nt:unknown protein) 21517891_f1_116 1445 18016 1092 363 102 −2 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16925380_f1_121 1446 18017 405 134 111 −7 Enterobacter cloacae CONTIG424 GTC ORF with score 211 to: (ai:7501777927) (or:Klebsiella pneumoniae) 17066580_f1_122 1447 18018 702 233 138 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12628805_f1_123 1448 18019 720 239 432 −40 Xanthomonas P45597 (sr:, pvcampestris) campestris (ec:2.7.3.9:2.7.1.69) (de:(eiii-fru))) 10726686_f1_124 1449 18020 2016 671 1268 −129 Klebsiella P45604 (ec:2.7.1.69) (de:enzyme ii, abc pneumoniae component), (eii-nag) 30120958_f1_129 1450 18021 582 193 377 −35 Klebsiella Contig350A GTC ORF with score 377 to: pneumoniae (ai:7000761521) (or:Pseudomonas aeruginosa) 3322582_f1_130 1451 18022 417 138 92 −2 Candida albicans P40954 (sr:, yeast) (ec:3.2.1.14) (de:chitinase 3 precursor,) 26019416_f1_131 1452 18023 432 143 317 −29 Klebsiella Contig387A GTC ORF with score 317 to: pneumoniae (ai:7000761523) (or:Pseudomonas aeruginosa) 32525308_f1_134 1453 18024 2088 695 801 −80 Haemophilus P44587 (de:hypothetical protein hi0232) influenzae 32689762_f1_135 1454 18025 402 133 136 −8 herpes simplex virus Z86099 (fn:immediate early protein; type 2 HSV-2 transciptional) (de:herpes simplex virus type 2 (strain hg52), complete genome.) 21960887_f1_136 1455 18026 1617 538 421 −40 Klebsiella Contig397A GTC ORF with score 421 to: pneumoniae (ai:7000761528) (or:Pseudomonas aeruginosa) 12628930_f1_139 1456 18027 1494 497 29791077_f1_141 1457 18028 486 161 257 −22 Enterococcus CONTIG484 GTC ORF with score 257 to: faecium C (ai:7000761533) (or:Pseudomonas aeruginosa) 14978958_f1_144 1458 18029 447 148 114 −6 Homo sapiens A37232 (sr:, man) 525042_f1_145 1459 18030 465 154 228 −19 Pyrococcus AP000001 (sr:pyrococcus horikoshii (str:ot3) horikoshii dna) (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 32438508_f1_148 1460 18031 1632 543 16536693_f1_149 1461 18032 387 128 269 −23 Klebsiella Contig519A GTC ORF with score 171 to: pneumoniae (de:pseudomonas fluorescens hypothetical metabolite transport protein, positive transcriptional regulator (phnr), phosphonoacetatehydrolase (phna), 2-phosphonopropionate transporter (phnb), putative putrescine/spermidine . . . 2910465_f1_150 1462 18033 1893 630 544 −52 Archaeoglobus O30107 (de:hypothetical protein af0130) fulgidus 32213566_f1_153 1463 18034 621 206 186 −14 Achromobacter A61183 georgiopolitanum 11738191_f1_155 1464 18035 2352 783 367 −30 Strongylocentrotus S23809 (cl:collagen alpha 2 (i) chain:fibrillar purpuratus collagen carboxyl-terminal homology) (sr:, purple urchin) 469841_c3_1010 1417 17988 1890 629 860 −87 Rickettsia prowazekii AJ235269 Rickettsia prowazekii strain Madrid E, complete genome. 10442816_c3_1012 1418 17989 1212 403 141 −9 Enterobacter cloacae CONTIG480 GTC ORF with score 141 to: (ai:7000761390) (or: Pseudomonas aeruginosa) 3260043_f1_5 1419 17990 1056 351 143 −6 Herpes simplex virus (type AF015297 (de:human herpesvirus 6 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate-early 2 protein of human) 31492917_f1_19 1420 17991 1572 523 9791566_f1_22 1421 17992 426 141 106 −6 Candida albicans CONTIG525 GTC ORF with score 106 to: 3 (ai:7000761414) (or: Pseudomonas aeruginosa) 10800066_f1_32 1422 17993 1266 421 130 −6 Klebsiella pneumoniae Contig275A GTC ORF with score 199 to: (ai:7000843618) (or: Enterobacter cloacae) 6308563_f1_46 1423 17994 573 190 91 −4 Klebsiella pneumoniae Contig536A GTC ORF with score 91 to: (ai:7000761438) (or: Pseudomonas aeruginosa) 22520300_f1_60 1424 17995 828 275 99 −5 Klebsiella pneumoniae Contig421A GTC ORF with score 177 to: (ai:7000821620) (or: Enterobacter cloacae) 20206455_f1_67 1425 17996 1356 451 163 −8 no gb taxonomy match U93872 (sr:kaposi's sarcoma- associated herpesvirus - human herpesvirus 8) (de: kaposi's sarcoma-associated herpesvirus glycoprotein m, dnareplication protein, glyco- protein, dna replication protein, fliceinhibitory protein and v-cyclin genes. . . . 26307665_f1_72 1426 17997 510 169 175 −13 Klebsiella pneumoniae Contig551A GTC ORF with score 217 to: (ai:7000761465) (or: Pseudomonas aeruginosa) 413966_f1_73 1427 17998 720 239 217 −18 Klebsiella pneumoniae Contig551A GTC ORF with score 217 to: (ai:7000761465) (or: Pseudomonas aeruginosa) 7160200_f1_75 1428 17999 1260 419 1269150_f1_82 1429 18000 1896 631 16300711_f1_84 1430 18001 3843 1280 120 −4 Sus scrofa domestica S55316 (sr:, domestic pig) 10167086_f1_85 1431 18002 612 203 100 −2 Dictyostelium discoideum AB009080 (sr:dictyostelium discoideum (str:ax2) dna) (de: dictyostelium discoideum gene for trfa, complete cds.) 22757216_f1_88 1432 18003 1398 465 2135841_f1_90 1433 18004 1230 409 23837791_f1_93 1434 18005 1437 478 34570187_f1_94 1435 18006 831 276 204 −17 Klebsiella pneumoniae Contig550A GTC ORF with score 714 to: (ai:7000838996) (or: Enterobacter cloacae) 12141657_f1_95 1436 18007 990 329 198 −15 Klebsiella pneumoniae Contig534A GTC ORF with score 278 to: (ai:7000828862) (or: Enterobacter cloacae) 2383561_f1_96 1437 18008 1302 433 145 −7 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 30332817_f1_102 1438 18009 1770 589 512 −49 Klebsiella pneumoniae Contig218A GTC ORF with score 664 to: (ai:7000815432) (or: Enterobacter cloacae) 15832250_f1_103 1439 18010 978 325 350 −32 Escherichia coli F65039 472965_f1_104 1440 18011 1305 434 840 −84 Escherichia coli D90888 (sr:escherichia coli (strain: k12) dna, clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #438(58.9-59.3 min.).) (nt: similar to (swissprot accession number p37908)) 31925681_f1_106 1441 18012 636 211 418 −39 Escherichia coli P37643 (de:region (o440)) 31673916_f1_110 1442 18013 1104 367 543 −53 Klebsiella pneumoniae Contig460A GTC ORF with score 543 to: (ai:7000761502) (or: Pseudomonas aeruginosa) 12995755_f1_111 1443 18014 666 221 159 −11 Klebsiella pneumoniae Contig560A GTC ORF with score 565 to: (ai:7000846961) (or: Enterobacter cloacae) 16507340_f1_113 1444 18015 798 265 372 −34 Arabidopsis thaliana U90439 (sr:thale cress) (de: arabidopsis thaliana chromosome ii bac t06d20 genomic sequence, complete sequence.) (nt:unknown protein) 21517891_f1_116 1445 18016 1092 363 102 −2 Boreogadus saida U43200 (de;boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16925380_f1_121 1446 18017 405 134 111 −7 Enterobacter cloacae CONTIG424 GTC ORF with score 211 to: (ai:7501777927) (or: Klebsiella pneumoniae) 17066580_f1_122 1447 18018 702 233 138 −7 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12628805_f1_123 1448 18019 720 239 432 −40 Xanthomonas campestris P45597 (sr:,pvcampestris) (ec: 2.7.3.9:2.7.1.69) (de:(eiii- fru))) 10726686_f1_124 1449 18020 2016 671 1268 −129 Klebsiella pneumoniae P45604 (ec:2.7.1.69) (de:enzyme ii, abc component), (eii-nag)) 30120958_f1_129 1450 18021 582 193 377 −35 Klebsiella pneumoniae Contig350A GTC ORF with score 377 to: (ai:7000761521) (or: Pseudomonas aeruginosa) 3322582_f1_130 1451 18022 417 138 92 −2 Candida albicans P40954 (sr:,yeast) (ec:3.2.1.14) (de: chitinase 3 precursor,) 26019416_f1_131 1452 18023 432 143 317 −29 Klebsiella pneumoniae Contig387A GTC ORF with score 317 to: (ai:7000761523) (or: Pseudomonas aeruginosa) 32525308_f1_134 1453 18024 2088 695 801 −80 Haemophilus influenzae P44587 (de:hypothetical protein hi0232) 32689762_f1_135 1454 18025 402 133 136 −8 herpes simplex virus type 2 Z86099 (fn:immediate early protein; HSV-2 transcriptional) (de:herpes simplex virus type 2 (strain hg52), complete genome.) 21960887_f1_136 1455 18026 1617 538 421 −40 Klebsiella pneumoniae Contig397A GTC ORF with score 421 to: (ai:7000761528) (or: Pseudomonas aeruginosa) 12628930_f1_139 1456 18027 1494 497 29791077_f1_141 1457 18028 486 161 257 −22 Enterococcus faecium CONTIG484 GTC ORF with score 257 to: C (ai:7000761533) (or: Pseudomonas aeruginosa) 14978958_f1_144 1458 18029 447 148 114 −6 Homo sapiens A37232 (sr:, man) 525042_f1_145 1459 18030 465 154 228 −19 Pyrococcus horikoshii AP000001 (sr:pyrococcus horikoshii (str: ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 32438508_f1_148 1460 18031 1632 543 16536693_f1_149 1461 18032 387 128 269 −23 Klebsiella pneumoniae Contig519A GTC ORF with score 171 to: (de:pseudomonas fluorescens hypothetical metabolite transport protein, positive transcriptional regulator (phnr), phosphonoacetate- hydrolase (phna), 2-phos- phonopropionate transporter (phnb), putative putrescine/ spermidine . . . 2910465_f1_150 1462 18033 1893 630 544 −52 Archaeoglobus fulgidus O30107 (de:hypothetical protein af0130) 32213566_f1_153 1463 18034 621 206 186 −14 Achromobacter A61183 georgiopolitanum 11738191_f1_155 1464 18035 2352 783 367 −30 Strongylocentrotus purpuratus S23809 (cl:collagen alpha 2(i) chain: fibrillar collagen carboxyl- terminal homology) (sr:, purple urchin) 15113317_f1_158 1465 18036 1917 638 707 −70 Haemophilus influenzae P44993 (de:hypothetical protein hi1029) 2213876_f1_159 1466 18037 2346 781 199 −15 Bacillus subtilis/Bacillus G69776 (cl:hypothetical protein yddq) globigii 16197532_f1_161 1467 18038 531 176 97 −5 Aspergillus fumigatus Contig9629 GTC ORF with score 116 to: (ai:7000774232) (or: Pseudomonas aeruginosa) 32676343_f2_165 1468 18039 426 141 137 −9 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 14144131_f2_168 1469 18040 549 182 12636305_f2_171 1470 18041 483 160 94 −2 mice|C57BL/6xCBA/CaJ S04336 (cl:unassigned ribonucleo- hybrid protein repeat-containing proteins:ribonucleoprotein repeat homology) (sr:, house mouse) 21664131_f2_172 1471 18042 834 277 133 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 30364216_f2_173 1472 18043 483 160 108 −4 Caenorhabditis elegans Z81503 (de:caenorhabditis elegans cosmid f14f7, complete sequence.) (nt:predicted using genefinder; similar to collagen;) 16289767_f2_174 1473 18044 471 156 127 −8 Enterobacter cloacae CONTIG495 GTC ORF with score 167 to: (ai:7501764598) (or: Klebsiella pneumoniae) 24882087_f2_175 1474 18045 444 147 14886550_f2_176 1475 18046 801 266 290 −25 Pseudomonas fluorescens L21198 (fn:major outer membrane protein) (sr:pseudomonas fluorescens dna) (de: pseudomonas fluorescens (pgsb 7941) protein f (oprf) gene, partialcds.) (nt: putative) 7206258_f2_177 1476 18047 771 256 196 −16 Klebsiella pneumoniae Contig289A GTC ORF with score 271 to: (ai:7000813428) (or: Enterobacter cloacae) 35276030_f2_187 1477 18048 210 69 99 −5 Enterobacter cloacae CONTIG493 GTC ORF with score 99 to: (ai:7000761579) (or: Pseudomonas aeruginosa) 21884577_f2_191 1478 18049 1152 383 116 −5 Enterobacter cloacae CONTIG479 GTC ORF with score 196 to: (ai:7000797019) (or: Pseudomonas aeruginosa) 26619580_f2_202 1479 18050 831 276 100 −2 Mycobacterium tuberculosis AL021841 (de:mycobacterium tuberculosis h37rv complete genome; segment 143/162.) (nt:rv3345c, (mtv004.01c- mtv016.45c), member of the m.) 1963506_f2_214 1480 18051 708 235 114 −5 Klebsiella pneumoniae Contig361A GTC ORF with score 105 to: (ai:69657) (or:Human herpes- virus 4) (cl:epstein-barr virus nuclear antigen) 22133441_f2_219 1481 18052 1512 503 25792902_f2_220 1482 18053 657 218 389 −36 Erwinia amylovora Y09848 (fn:activator of exopoly- saccharide synthesis) (de: e.amylovora resb gene.) 13151058_f2_221 1483 18054 924 307 6370468_f2_222 1484 18055 1632 543 10441030_f2_223 1485 18056 417 138 288 −25 Neisseria meningitidis P25138 (ec:5.2.1.8) (de:(ec 5.2.1.8) (rotamase)) 13087953_f2_226 1486 18057 759 252 99 −2 Escherichia coli D90774 (sr:escherichia coli (strain: k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 6519702_f2_228 1487 18058 765 254 137 −8 Mycobacterium tuberculosis Z92539 (de:mycobacterium tuberculosis h37rv complete genome; segment 47/162.) (nt: rv1019, (mtcy10g2.30c), len: 197. probable) 16151956_f2_231 1488 18059 510 169 205 −17 Aspergillus fumigatus v3x12050.x GTC ORF with score 205 to: (ai:7000761623) (or: Pseudomonas aeruginosa) 22146030_f2_235 1489 18060 1386 461 261 −22 Enterobacter cloacae CONTIG493 GTC ORF with score 261 to: (ai:7000761627) (or: Pseudomonas aeruginosa) 32672915_f2_236 1490 18061 234 77 91 −5 Enterobacter cloacae CONTIG502 GTC ORF with score 141 to: (ai:1500696760) (or:Homo sapiens) (sr:homo sapiens cdna to mrna) (de:homo sapiens mrna for n-wasp, complete cds.) 16924166_f2_243 1491 18062 906 301 152 −7 Herpes simplex virus (type AF015297 (de:human herpesvirus 6 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate-early 2 protein of human) 36032718_f2_250 1492 18063 1740 579 111 −4 Klebsiella pneumoniae Contig540A GTC ORF with score 131 to: (ai:7000804742) (or: Pseudomonas aeruginosa) 14322133_f2_256 1493 18064 1233 410 533 −51 Sphingomonas AF079317 (de:sphingomonas aromaticivorans aromaticivorans plasmid pn11, complete plasmid- sequence.) (nt:putative inner membrane protein similar to b.) 11192930_f2_266 1494 18065 1956 651 786 −78 Cyanobacterium synechocystis S75742 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 14552041_f2_267 1495 18066 708 235 117 −5 Homo sapiens E25372 (cl:proline-rich protein) (sr:, man) (mp:12p13.2-12p13.2) 31695430_f2_270 1496 18067 873 290 220 −18 Enterobacter cloacae CONTIG254 GTC ORF with score 220 to: (ai:7000761662) (or: Pseudomonas aeruginosa) 36412568_f2_271 1497 18068 1089 362 124 −7 Pyrococcus horikoshii AP000006 (sr:pyrococcus horikoshii (str: ot3) dna, (cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position (6/7).) 26697582_f2_272 1498 18069 459 152 246 −21 Enterococcus faecium CONTIG143 GTC ORF with score 399 to: C (ai:7000726277) (or: Streptococcus pneumoniae) 10244830_f2_278 1499 18070 990 329 775 −77 Escherichia coli P37643 (de:region (o440)) 12635431_f2_281 1500 18071 567 188 337 −31 Klebsiella pneumoniae Contig460A GTC ORF with score 337 to: (ai:7000761673) (or: Pseudomonas aeruginosa) 7119031_f2_284 1501 18072 996 331 170 −10 Klebsiella pneumoniae Contig452A GTC ORF with score 473 to: (ai:7000824041) (or: Enterobacter cloacae) 22831875_f2_287 1502 18073 795 264 334 −30 Bacillus subtilis/Bocillus D70044 globigii 34632206_f2_288 1503 18074 2127 708 355 −29 Thermus thermophilus/ Q56213 (sr:,subspthermophilus) (cc: T.aquaticus/T.flavus 2.6.1.16) (de:amido- transferase) (glucosamine-6- phosphate synthase)) 22005208_f2_289 1504 18075 936 311 110 −3 Klebsiella pneumoniae P33906 (de:atp-dependent rna helicase dead) 10682091_f2_290 1505 18076 1038 345 156 −8 Nephila clavipes A44112 22301393_f2_310 1506 18077 444 147 91 −3 Enterobacter cloacae CONTIG337 GTC ORF with score 395 to: (ai:7501739904) (or: Klebsiella pneumoniae) 9902325_f2_318 1507 18078 576 191 114 −4 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 30210400_f2_321 1508 18079 1251 416 116 −3 Klebsiella pneumoniae U10553 (fn:trans-acting regulatory protein of aco operon) (de: klebsiella pneumoniae cg43 aco operon regulatory protein acok(acok) gene, complete cds.) (nt:contains a nucleotide binding domain and) 12629031_f2_322 1509 18080 429 142 148 −9 Caenorhabditis elegans U80846 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 5166037_f2_324 1510 18081 927 308 475 −45 Klebsiella pneumoniae Contig519A GTC ORF with score 171 to: (de:pseudomonas fluorescens hypothetical metabolite transport protein, positive transcriptional regulator (phnr), phosphonoacetate- hydrolase (phna), 2- phosphonopropionate transporter (phnb), putative putrescine/spermidine . . . 24469431_f2_329 1511 18082 939 312 392 −36 Klebsiella terrigena P52666 (de:bud operon transcriptional regulator) 12145205_f2_330 1512 18083 1416 471 936 −94 Haemophilus influenzae P43913 (ec:3.1.11.6) (de:large subunit)) 5119783_f2_331 1513 18084 942 313 285 −25 Rhizobium leguminosarum U39409 (de:rhizobium leguminosarum bv. trifolii bv. trifolii tfua (tfua), gene, completecds.) (nt:orf1; high similarity to members of the lysr) 31895841_f2_332 1514 18085 801 266 120 −7 Enterobacter cloacae CONTIG24 GTC ORF with score 133 to: (ai:286830) (or:Ensis minor) (sr:ensis minor (clone: 1/6) male adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 2598881_f2_333 1515 18086 690 229 99 −3 Escherichia coli P37674 (de:hypothetical 17.5 kd protein in avta-selb intergenic region (o157a)) 29970656_f2_335 1516 18087 795 264 268 −23 Cyanobacterium synechocystis S75903 (sr:pcc 6803, , pcc 6803) (sr: pcc 6803, ) 15739656_f2_339 1517 18088 480 159 180 −13 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 6300082_f3_344 1518 18089 885 294 460 −44 Klebsiella pneumoniae Contig441A GTC ORF with score 612 to: (ai:7000835977) (or: Enterobacter cloacae) 22667086_f3_345 1519 18090 1593 530 508 −49 Klebsiella pneumoniae Contig441A GTC ORF with score 612 to: (ai:7000835977) (or: Enterobacter cloacae) 36506450_f3_350 1520 18091 2268 755 1379 −141 Staphylococcus aureus P37386 (ec:3.6.1.—) (de:atpase)) 33485005_f3_357 1521 18092 1575 524 12364062_f3_358 1522 18093 1770 589 802 −80 Klebsiella pneumoniae Contig550A GTC ORF with score 1626 to: (ai:7000838990) (or: Enterobacter cloacae) 25832277_f3_359 1523 18094 1026 341 687 −68 Klebsiella pneumoniae Contig550A GTC ORF with score 687 to: (ai:7000761751) (or: Pseudomonas aeruginosa) 3366375_f3_360 1524 18095 1284 427 103 −2 Achromobacter L81125 (sr:pseudomonas sp (strain georgiopolitanum imt37) dna) (de:pseudomonas sp. (strain imt37) mono- oxygenase subunit gene, completecds.) 31876058_f3_363 1525 18096 546 181 93 −2 Aspergillus fumigatus Contig8154 GTC ORF with score 433 to: (ai:177837) (or:Zea mays) (sr:, maize) 17038417_f3_364 1526 18097 927 308 151 −7 Saccharomyces cerevisiae Q04893 (sr:,baker's yeast) (de: hypothetical 113.1 kd protein in pre5-fet4 intergenic region) 16135453_f3_369 1527 18098 867 288 125 −7 Pyrococcus horikoshii AP000002 (sr:pyrococcus horikoshii (str: ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position (2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 3395438_f3_371 1528 18099 1785 594 94 −1 Oenothera picensis S29795 (sr:, evening primrose) picensis 36019441_f3_372 1529 18100 726 241 216 −18 Klebsiella pneumoniae Contig536A GTC ORF with score 662 to: (ai:7000758235) (or: Pseudomonas aeruginosa) 2226081_f3_374 1530 18101 1029 342 291 −26 Escherichia coli P45463 (de:hypothetical transcriptional regulator in baca-ttda intergenic region) 15891467_f3_376 1531 18102 2034 677 99 −1 Mycobacterium tuberculosis Z83864 (de:mycobacterium tuberculosis h37rv complete genome; segment 159/162.) (nt:rv3854c, (mtcy01a6.14), len: 489. possible) 33597541_f3_398 1532 18103 546 181 97 −3 Gallus gallus domesticus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene coding for phosvitin, exons 23 and24.) 32283283_f3_410 1533 18104 534 177 98 −5 Klebsiella pneumoniae Contig545A GTC ORF with score 107 to: (ai:139109) (or:Glycine max) (cl:human dna-directed rna polymerase ii largest chain) (sr:, soybean) (ec:2.7.7.6) 32671908_f3_411 1534 18105 1806 601 163 −8 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 30210965_f3_417 1535 18106 474 157 119 −6 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14661393_f3_421 1536 18107 2025 674 16423325_f3_431 1537 18108 723 240 136 −6 Vibrio cholerae L19085 (sr:vibrio cholerae (strain n16961) dna) (de:vibrio cholerea mannose-sensitive hemagglutinin d (mshd) gene, complete cds and mannose- sensitive hemagglutinin e (mshe) gene, partial cds.) 31741633_f3_439 1538 18109 564 187 150 −9 equine herpesvirus type 4 AF030027 (fn:very large tegument EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene ul36 and vzv gene 22) 31376011_f3_440 1539 18110 1671 556 153 −8 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 16026061_f3_444 1540 18111 687 228 120 −4 Hemicentrotus pulcherrimus S42731 (cl:collagen alpha 2(i) chain: fibrillar collagen carboxyl- terminal homology) 31734408_f3_449 1541 18112 411 136 99 −4 Streptomyces coriofaciens L20249 (sr:streptomyces coriofaciens (library: isp 5485) dna) (de: streptomyces coriofaciens betaketoacyl synthase homologue gene, partial cds.) (nt:homologous to saccharopolyspora erythraca) 24633438_f3_450 1542 18113 573 190 13772831_f3_452 1543 18114 1164 387 555 −53 Vibrio furnissii P96166 (ec:3.5.1.25) (de:deacetylase)) 12589058_f3_455 1544 18115 2061 686 732 −72 Xanthomonas campestris P45597 (sr:,pvcampestris) (ec:2.7.3.9: 2.7.1.69) (de:(eiii-fru))) 12994577_f3_457 1545 18116 456 151 106 −6 longfin squid S56117 (sr:, longfin squid) 12754501_f3_459 1546 18117 1068 355 154 −8 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 20517261_f3_460 1547 18118 4359 1452 1131 −115 Enterobacter cloacae CONTIG396 GTC ORF with score 1739 to: (ai:7501736107) (or: Klebsiella pneumoniae) 34192941_f3_462 1548 18119 1566 521 147 −10 Aspergillus fumigatus Contig9612 GTC ORF with score 147 to: (ai:7000761854) (or: Pseudomonas aeruginosa) 862502_f3_469 1549 18120 1005 334 737 −73 Klebsiella pneumoniae Contig448A GTC ORF with score 2000 to: (ai:7000821054) (or: Enterobacter cloacae) 35176711_f3_470 1550 18121 735 244 431 −41 Klebsiella pneumoniae Contig448A GTC ORF with score 2000 to: (ai:7000821054) (or: Enterobacter cloacae) 31508505_f3_471 1551 18122 1512 503 121 −5 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 15/162.) (nt: rv0278c, (mtv035.06c), len: 957. member of m.) 15100753_f3_476 1552 18123 1272 423 109 −3 Klebsiella pneumoniae Contig519A GTC ORF with score 171 to: (de:pseudomonas fluorescens hypothetical metabolite transport protein, positive transcriptional regulator (phnr), phosphonoacetate- hydrolase (phna), 2- phosphonopropionate transporter (phnb), putative putrescine/spermidine . . . 14547707_f3_478 1553 18124 1779 592 6355030_f3_484 1554 18125 528 175 121 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 25972302_f3_487 1555 18126 1158 385 359 −33 Escherichia coli P37676 (de:hypothetical 36.0 kd protein in avta-selb intergenic region precursor) 29928781_f3_488 1556 18127 1362 453 133 −6 Streptomyces coelicolor AL031155 (de:streptomyces coelicolor cosmid 3a7.) (nt:sc3a7.04, questionable orf, : 384 aa; this orf) 9884783_f3_489 1557 18128 831 276 181 −11 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 13127333_f3_491 1558 18129 1554 517 23964512_c1_497 1559 18130 489 162 167 −12 Streptomyces lividans P49322 (de:hypothetical protein in cpol 5′region (orf1) (fragment)) 2629788_c1_498 1560 18131 501 166 254 −22 Streptomyces aureofaciens U21191 (fn:unknown) (de: streptomyces aureofaciens glyceraldehyde-3-phosphate dehydrogenase(gap) gene, complete cds, arac family transcription activatorhomolog and delta-5-3-ketosteroid isomerase homolog (ksi) genes, partial cds.) (nt:arac family . . . 15021033_c1_500 1561 18132 1587 528 189 −12 Bordetella pertussis P33445 (de:hypothetical 33.8 kd protein in fhac 3′region (orfa)) 477066_c1_507 1562 18133 858 285 155 −8 Homo sapiens PN0099 (sr:, man) 11968917_c1_513 1563 18134 1080 359 507 −49 Klebsiella pneumoniae Contig519A GTC ORF with score 507 to: (ai:7000761905) (or: Pseudomonas aeruginosa) 10989775_c1_514 1564 18135 468 155 91 −2 Caenorhabditis elegans AF000198 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 36148886_c1_520 1565 18136 876 291 134 −8 longfin squid S56117 (sr:, longfin squid) 35728328_c1_521 1566 18137 1659 552 154 −7 Burkholderia cepacia U41162 (sr:burkholderia cepacia strain=17616) (de: burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 17070463_c1_522 1567 18138 1536 511 318 −26 Pseudomonas syringae P12374 (sr:,pvtomato) (de:copper resistance protein a precursor) 32156260_c1_525 1568 18139 1479 492 223 −16 Escherichia coli P18199 (de:tyrosine-specific transport protein (tyrosine permease)) 13133327_c1_526 1569 18140 1611 536 180 −13 Klebsiella pneumoniae Contig387A GTC ORF with score 180 to: (ai:7000761918) (or: Pseudomonas aeruginosa) 31886391_c1_530 1570 18141 759 252 147 −7 Burkholderia cepacia U41162 (sr:burkholderia cepacia strain=17616) (de: burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 36111661_c1_531 1571 18142 486 161 105 −3 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase-binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein;) 6914581_c1_532 1572 18143 1155 384 114 −3 Neisseria gonorrhoeae S75490 (sr:neisseria gonorrhoeae ms11) (de:competence region: iga=iga protease, coma= transformation competence (neisseria gonorrhoeae, ms11, genomic, 3 genes, 2664 nt).) 11179081_c1_534 1573 18144 2022 673 147 −6 African clawed frog U85970 (sr:african clawed frog) (de: xenopus laevis middle molecular weight neuro- filament proteinnf-m(2) mrna, complete cds.) (nt:neuronal intermediate filament protein; duplicated) 6540791_c1_535 1574 18145 654 217 108 −4 Enterobacter cloacae CONTIG481 GTC ORF with score 255 to: (ai:7000808495) (or: Pseudomonas aeruginosa) 32286003_c1_548 1575 18146 567 188 905 −91 Pseudomonas aeruginosa P40882 (de:ferripyochelin binding protein) 34494683_c1_549 1576 18147 1299 432 1324 −135 Escherichia coli A54227 (cl:phosphoribosylamino- imidazole carboxylase carbon dioxide-fixation chain: phosphoribosylamino- imidazole carboxylase carbon dioxide-fixation chain homology) (ec:2.1.2.—) 25885376_c1_555 1577 18148 477 158 134 −8 Mycobacterium tuberculosis Z81368 (de:mycobacterium tuberculosis h37rv complete genome; segment 106/162.) (nt:rv2396, (mtcy253.25c), len: 361. member of pe) 23960200_c1_557 1578 18149 663 220 253 −22 Klebsiella pneumoniae Contig064A GTC ORF with score 484 to: (ai:7000815407) (or: Enterobacter cloacae) 36510806_c1_558 1579 18150 960 319 139 −6 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 11823793_c1_560 1580 18151 1485 494 1647 −169 Haemophilus influenzae P44518 (de:signal recognition particle protein (fifty-four homolog)) 11751967_c1_562 1581 18152 255 84 94 −5 Aspergillus fumigatus Contig9333 GTC ORF with score 136 to: (ai:203141) (or:Rattus norvegicus) (sr:, norway rat) 20210166_c1_571 1582 18153 951 316 926 −93 Proteus mirabilis AF033497 (de:proteus mirabilis site- specific recombinase (xerd) gene, completecds.) (nt: tyrosine recombinase family) 6509661_c1_572 1583 18154 732 243 1228 −125 Pseudomonas aeruginosa AF057031 (de:pseudomonas aeruginosa putative th:disulfide inter- change proteinprecursor (dsbc) gene, complete cds.) (nt:dsbc) 2088515_c1_573 1584 18155 1473 490 1875 −193 Pseudomonas aeruginosa P29365 (ec:1.1.1.3) (de:homoserine dehydrogenase, (hdh)) 4386015_c1_584 1585 18156 630 209 188 −15 Escherichia coli P39291 (de:hypothetical 14.9 kd protein in vacb-aidb intergenic region (o133a)) 17070342_c1_587 1586 18157 717 238 13088330_c1_591 1587 18158 669 222 124 −5 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 13072958_c1_592 1588 18159 5337 1778 93 −1 Thermus thermophilus/ Q56214 (sr:,subspthermophilus) (de: T.aquaticus/T.flavus holliday junction dna helicase ruvb) 26770193_c1_593 1589 18160 711 236 179 −15 Rickettsia prowazekii AJ235269 Rickettsia prowazekii strain Madrid E, complete genome. 25916333_c1_597 1590 18161 1545 514 2601 −270 Pseudomonas aeruginosa P14756 (ec:3.4.24.26) (de:metallo- proteinase)) 6147517_c1_598 1591 18162 1152 383 809 −80 Bacillus subtilis/Bacillus P54550 (ec:1.—.—.—) (de:probable globigii nadh-dependent flavin oxido- reductase yqjm,) 4956508_c1_601 1592 18163 1308 435 221 −15 Streptomyces pristinaespiralis S70171 11927056_c1_615 1593 18164 579 192 123 −6 Alphaherpesvirus pseudo- X79983 (de:pseudorabies virus dna.) rabies virus PRV (nt:putative assembly protein) 32526043_c1_618 1594 18165 1521 506 32667532_c1_623 1595 18166 570 189 120 −6 Lyme disease spirochete D70170 (sr:, lyme disease spirochete) 7073432_c1_627 1596 18167 696 231 15822950_c1_629 1597 18168 1521 506 810 −79 Pseudomonas aeruginosa U79580 (de:pseudomonas aeruginosa pilk gene, partial cds; and pill, chpa, chpb, chpc, chpd, and chpe genes, complete cds.) (nt:cheay homolog) 25567930_c1_632 1598 18169 1005 334 176 −10 Gallus gallus domesticus I50206 (cl:collagen alpha 2(i) chain: fibrillar collagen carboxyl- terminal homology) (sr:, chicken) 11963257_c1_634 1599 18170 894 297 141 −9 Klebsiella pneumoniae Contig429A GTC ORF with score 141 to: (ai:7000762026) (or: Pseudomonas aeruginosa) 2214691_c1_635 1600 18171 813 270 142 −10 Klebsiella pneumoniae Contig429A GTC ORF with score 142 to: (ai:7000762027) (or: Pseudomonas aeruginosa) 24738900_c1_636 1601 18172 774 257 108 −6 Klebsiella pneumoniae Contig411A GTC ORF with score 108 to: (ai:7000762028) (or: Pseudomonas aeruginosa) 25672941_c1_638 1602 18173 1509 502 14569568_c1_640 1603 18174 1239 412 97 −2 Plasmodium knowlesi P04922 (sr:nuri,) (de:circumsporozoite protein precursor (cs)) 14975752_c1_650 1604 18175 801 266 286 −25 Haemophilus influenzae P45277 (de:hypothetical transcriptional regulator hi1623) 32714583_c1_652 1605 18176 975 324 139 −7 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 123/162.) (nt:rv2839c, (mtcy16b7.03), len: 900. probable infb.) 2477041_c1_653 1606 18177 1542 513 126 −5 Aspergillus fumigatus Contig8665 GTC ORF with score 154 to: (ai:7501004138) (or:Mus musculus) (sr:house mouse) (de:mus musculus plenty-of- prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 31656291_c2_657 1607 18178 1311 436 100 −3 Klebsiella pneumoniae Contig548A GTC ORF with score 90 to: (ai:158543) (or:Orf virus) (sr: orf virus (strain nz2) dna) (de: orf virus homologue of retro- viral pseudoprotease gene, completecds.) (nt:orf4) 6355205_c2_659 1608 18179 189 62 90 −4 Klebsiella pneumoniae Contig498A GTC ORF with score 90 to: (ai:7000762051) (or: Pseudomonas aeruginosa) 30167642_c2_663 1609 18180 414 137 110 −7 Enterobacter cloacae CONTIG495 GTC ORF with score 172 to: (ai:7000779951) (or: Pseudomonas aeruginosa) 9769381_c2_664 1610 18181 462 153 104 −4 Enterobacter cloacae CONTIG495 GTC ORF with score 140 to: (ai:7000779952) (or: Pseudomonas aeruginosa) 16915933_c2_665 1611 18182 1314 437 13016333_c2_668 1612 18183 441 146 151 −9 Nephila clavipes AF027972 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 6505168_c2_670 1613 18184 522 173 135 −8 Nephila clavipes AF027972 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 7213517_c2_671 1614 18185 813 270 31929182_c2_675 1615 18186 432 143 194 −16 Klebsiella pneumoniae Contig519A GTC ORF with score 194 to: (ai:7000762067) (or: Pseudomonas aeruginosa) 20885266_c2_678 1616 18187 1677 558 1601 −164 Acinetobacter calcoaceticus P31002 (ec:1.1.1.205) (de: dehydrogenase) (impdh) (impd)) 16839191_c2_679 1617 18188 1590 529 1982 −205 Escherichia coli P04079 (ec:6.3.5.2) (de:amido- transferase) (gmp synthetase)) 11897155_c2_684 1618 18189 591 196 124 −5 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 13147887_c2_688 1619 18190 4293 1430 4335 −9999 Escherichia coli P15254 (ec:6.3.5.3) (de:synthase) (formylglycinamide ribotide amidotransferase) (fgarat)) 2628913_c2_689 1620 18191 909 302 141 −7 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11207291_c2_691 1621 18192 420 139 159 −12 Klebsiella pneumoniae Contig114A GTC ORF with score 305 to: (ai:7000815986) (or: Enterobacter cloacae) 13025331_c2_692 1622 18193 666 221 105 −6 Klebsiella pneumoniae Contig553A GTC ORF with score 138 to: (ai:7000757300) (or: Pseudomonas aeruginosa) 31880211_c2_695 1623 18194 612 203 117 −6 Enterobacter cloacae CONTIG511 GTC ORF with score 126 to: (ai:7000725906) (or: Streptococcus pneumoniae) 11172542_c2_698 1624 18195 1209 402 1433416_c2_702 1625 18196 861 286 124 −5 Epstein-Barr virus P03181 (sr:b95-8, human herpesvirus 4) (de:hypothetical bhlf1 protein) 5339708_c2_704 1626 18197 900 299 15121081_c2_708 1627 18198 228 75 90 −4 Klebsiella pneumoniae Contig389A GTC ORF with score 438 to: (ai:7000835991) (or: Enterobacter cloacae) 16838162_c2_709 1628 18199 507 168 105 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 4567088_c2_720 1629 18200 360 119 417 −39 Escherichia coli S07951 (cl:escherichia coli ribosomal protein 119) (mp:57 min) 22444181_c2_721 1630 18201 480 159 116 −7 Zymomonas mobilis X93605 (de:zymomonas mobilis pdhb & lpd genes & orf's 4, 5, 6, 7 & 8.) 12000641_c2_725 1631 18202 195 64 14704752_c2_733 1632 18203 1467 488 2311 −240 Pseudomonas aeruginosa X65033 (ec:4.2.99.2) (de:p.aeruginosa hom and thrc genes for homo- serine dehydrogenase and threonine synthase.) 30267905_c2_736 1633 18204 369 122 13175837_c2_740 1634 18205 840 279 157 −8 Nephila clavipes U37520 (de:nephila clavipes dragline silk protein spidroin 1 gene, partialcds.) 15758518_c2_745 1635 18206 1071 356 248 −19 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 11222955_c2_747 1636 18207 489 162 171 −12 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34614767_c2_757 1637 18208 420 139 122 −6 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 4010455_c2_758 1638 18209 702 233 275 −24 Salmonella choleraesuis O33809 (de:hypothetical 20.8 kd serotype typhimurium protein in mesj-cutf intergenic region) 20829756_c2_759 1639 18210 1770 589 149 −7 Homo sapiens Y13247 (sr:human) (de:homo sapiens fb19 mrna.) 31492711_c2_766 1640 18211 372 123 109 −6 Paracentrotus lividus A32249 (cl:collagen alpha 2(i) chain:fibrillar collagen carboxyl-terminal homology) (sr:, common urchin) 3335841_c2_771 1641 18212 567 188 131 −7 Aspergillus fumigatus Contig9870 GTC ORF with score 111 to: (ai:195953) (or:Homo sapiens) (sr:, man) 20000313_c2_775 1642 18213 1332 443 32509761_c2_777 1643 18214 828 275 238 −20 Escherichia coli P33218 (de:hypothetical 23.7 kd protein in ptrb-purt intergenic region (orf153)) 2610332_c2_779 1644 18215 1758 585 1026 −103 Pseudomonas oleovorans Q00593 (ec:1.1.99.—) (de:alcohol dehydrogenase (acceptor),) 30277062_c2_780 1645 18216 1674 557 583 −56 Burkholderia cepacia U29532 (fn:4-methyl-o-phthalate/ phthalate permease) (de: burkholderia cepacia plasmid pmop pdxa homolog gene, partial cds, 4-methyl-o- phthalate reductase (mopa) and 4-methyl-o-phthalate- permease (mopb) genes, complete cds.) 32672191_c2_782 1646 18217 843 280 144 −7 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 33791280_c2_784 1647 18218 1479 492 29821041_c2_787 1648 18219 1194 397 160 −9 Achromobacter A61183 georgiopolitanum 13025833_c2_793 1649 18220 1119 372 471 −45 Cyanobacterium synechocystis S75143 (cl:response regulator homology) (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 20838342_c2_794 1650 18221 1176 391 1242 −126 Salmonella choleraesuis P28353 (de:peptide chain release serotype typhimurium factor 2 (rf-2)) 14180431_c2_795 1651 18222 1524 507 1663 −171 Acinetobacter calcoaceticus Q43990 (ec:6.1.1.6) (de:lysyl- trna synthetase, (lysine-- trna ligase) (lysrs)) 25432091_c2_796 1652 18223 780 259 170 −13 Mycobacterium tuberculosis Z83866 (de:mycobacterium tuberculosis h37rv complete segment 133/162.) (nt:rv3066, (mtcy22d7.15c), len: 202. some similarity) 21745381_c2_797 1653 18224 648 215 10626092_c2_799 1654 18225 1986 661 305 −26 Escherichia coli E65030 14859387_c2_804 1655 18226 1293 430 195 −15 Enterobacter cloacae CONTIG495 GTC ORF with score 195 to: (ai:7000762196) (or: Pseudomonas aeruginosa) 22917711_c2_805 1656 18227 1152 383 212 −17 Klebsiella pneumoniae Contig502A GTC ORF with score 488 to: (ai:7000839835) (or: Enterobacter cloacae) 7057783_c2_808 1657 18228 2406 801 2287 −237 Escherichia coli P00864 (ec:4.1.1.31) (de: phosphoenolpyruvate carboxylase, (pepcase) (pepc)) 34266588_c2_809 1658 18229 354 118 323 −29 Bordetella pertussis S66937 (de:orf1 . . . orf3 {transposon- like sequence} (bordetella pertussis, genomic, 3 genes, 2300 nt).) 6337692_c3_810 1659 18230 450 149 590 −57 Brodetella pertussis S66937 (de:orf1 . . . orf3 {transposon- like sequence} (bordetella pertussis, genomic, 3 genes, 2300 nt).) 22947893_c3_811 1660 18231 573 190 30175751_c3_812 1661 18232 540 179 199 −16 Aquifex aeolicus C70408 29696043_c3_815 1662 18233 1821 606 116 −3 Caenorhabditis elegans AF026211 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid t13b5.) (nt:similar to cuticular collagen) 3251651_c3_821 1663 18234 3429 1142 98 −1 common tobacco S34666 (cl:phaseolus glycine-rich protein 1.0) (sr:, common tobacco) 32520217_c3_840 1664 18235 1350 449 417 −39 Haemophilus influenzae P44931 (de:hyopthetical protein hi0906) 21043_c3_844 1665 18236 681 226 287 −25 Acinetobacter baumannii CONTIG192 GTC ORF with score 287 to: C (ai:7000762236) (or: Pseudomonas aeruginosa) 12223915_c3_855 1666 18237 420 139 32160207_c3_856 1667 18238 483 160 236 −19 Mycobacterium leprae AL023635 (de:mycobacterium laprae cosmid b1243.) (nt: mlcb1243.36, unknown, : 385 aa; similar to) 29946958_c3_861 1668 18239 618 205 138 −7 Sus scrofa domestica S55316 (sr:, domestic pig) 30722902_c3_862 1669 18240 609 202 144 −8 human herpesvirus U92288 (fn:helicase, helicase- type 6 HHV-6 primase complex) (de: human herpesvirus 6 serotype b putative major immediate- carlygenes.) (nt:similar to hhv6a u86, region ie-b) 31760465_c3_863 1670 18241 1296 431 200 −14 Enterobacter cloacae CONTIG273 GTC ORF with score 135 to: (ai:105942) (or:Equine herpesvirus 1) (sr:ab4p,ehv-1) (de:glycoprotein x precursor) 29963333_c3_866 1671 18242 1200 399 16902042_c3_868 1672 18243 963 320 318 −28 Escherichia coli P43337 (de:hypothetical 21.4 kd protein in pabb-sdaa intergenic region) 26032943_c3_869 1673 18244 726 241 114 −6 Escherichia coli P76188 (de:hypothetical 14.4 kd protein in sodc-nema intergenic region precursor) 31649167_c3_870 1674 18245 1590 529 117 −3 blue mussel AF015539 (sr:blue mussel) (de: mytilus edulis precollagen p (precol-p) mrna, complete cds.) 26432881_c3_872 1675 18246 1131 376 122 −4 Saimiriine herpesvirus 2 Q01042 (sr:11,) (de:immediate- early protein) 29426030_c3_878 1676 18247 411 136 91 −3 Aspergillus fumigatus Contig136 GTC ORF with score 865 to: (ai:74529) (or:Petunia x hybrida) (sr:,petunia) (de: glycine-rich cell wall structural protein 1 precursor) 20521905_c3_882 1677 18248 333 110 270 −23 Haemophilus influenzae P44382 (de:30s ribosomal protein s16) 34409783_c3_883 1678 18249 543 180 360 −33 Haemophilus influenzae P44568 (de:16s rrna processing protein rimm) 26597555_c3_884 1679 18250 765 254 885 −88 Escherichia coli P07020 (ec:2.1.1.31) (de:methyl- transferase)) 6522583_c3_885 1680 18251 939 312 150 −10 Bacillus subtilis/Bacillus P49851 (de:hypothetical 20.1 kd globigii protein in hmp 5′region (orf1)) 6503216_c3_887 1681 18252 1248 415 116 −3 Dictyostelium discoideum AB009080 (sr:dictyostelium discoideum (str:ax2) dna) (de: dictyostelium discoideum gene for trfa, complete cds.) 31907212_c3_890 1682 18253 1020 339 99 −2 Homo sapiens P10163 (sr:,human) (de:salivary proline-rich protein po precursor (allele s)) 1386638_c3_892 1683 18254 714 237 92 −4 longfin squid S56117 (sr:, longfin squid) 12125781_c3_898 1684 18255 1353 450 14579528_c3_900 1685 18256 1335 444 341 −31 Escherichia coli P39292 (de:(o232)) 34647563_c3_902 1686 18257 1695 564 485 −46 Escherichia coli A65093 17072930_c3_915 1687 18258 1839 612 1692 −174 Escherichia coli P21893 (ec:3.1.—.—) (de:single- stranded-dna-specific exonuclease recj,) 11798140_c3_923 1688 18259 405 134 12394657_c3_925 1689 18260 768 255 10331656_c3_927 1690 18261 3591 1196 31886037_c3_930 1691 18262 456 151 103 −5 Klebsiella pneumoniae Contig275A GTC ORF with score 280 to: (ai:7000843367) (or: Enterobacter cloacae) 24472701_c3_938 1692 18263 360 119 104 −6 Homo sapiens I53641 (sr:, man) (mp:11p15.5- 11p15.5) 7166430_c3_943 1693 18264 1962 653 426 −39 Bacillus subtilis/ F70028 Bacillus globigii 36441592_c3_945 1694 18265 1368 455 321 −29 Rhodospirillum centenum U64519 (de:rhodospirillum centenum (Rhodocista centenaria) cheay, chew, chey, cheb, and cher genes, complete cds.) 12712701_c3_946 1695 18266 1566 521 176 −10 Treponema pallidum AE001215 (de:treponema pallidum section 31 of 87 of the complete genome.) (nt:similar to gp:1765973 percent ident: 99.75;) 16303966_c3_947 1696 18267 888 295 148 −7 Oryctolagus cuniculus P27884 (sr:,rabbit) (de:brain calcium channel bi-2 protein) 35281418_c3_949 1697 18268 1053 350 436 −41 Archaeoglobus fulgidus A69380 29822931_c3_953 1698 18289 543 180 195 −14 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14972580_c3_960 1699 18270 456 151 102 −5 Aspergillus fumigatus Contig3749 GTC ORF with score 178 to: (ai:203144) (or:Rattus norvegicus) (sr:, norway rat) 12987832_c3_962 1700 18271 2181 726 337 −29 Archaeoglobus fulgidus B69328 2438391_c3_964 1701 18272 828 275 427 −40 Ralstonia eutropha I39569 16490668_c3_965 1702 18273 807 268 114 −5 Klebsiella pneumoniae Contig463A GTC ORF with score 544 to: (ai:7000821222) (or: Enterobacter cloacae) 32427062_c3_967 1703 18274 681 226 106 −3 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 24745832_c3_970 1704 18275 555 184 263 −23 Enterobacter cloacae CONTIG311 GTC ORF with score 263 to: (ai:7000762362) (or: Pseudomonas aeruginosa) 13161653_c3_971 1705 18276 447 148 94 −2 mice|C57BL/6xCBA/CaJ P54728 (sr:,mouse) (de:repair hybrid complementing complex 58 kd protein) (p58)) 31739068_f1_1 1706 18277 1818 605 407 −38 Rhodococcus sp. Q53139 (sr:ni86/21,) (ec:1.3.1.54) (de: precorrin-6x reductase,) 12367292_f1_2 1707 18278 660 219 213 −18 Enterobacter cloacae CONTIG304 GTC ORF with score 213 to: (ai:7000762372) (or: Pseudomonas aeruginosa) 13008513_f1_4 1708 18279 2172 723 472 −42 Pseudomonas aeruginosa AF051693 (de:pseudomonas aeruginosa hydroxamate-type ferrisiderophore receptor (pfua) gene, complete cds.) (nt:pfua) 12785282_f1_5 1709 18280 1764 587 162 −7 equine herpesvirus type AF030027 (fn:very large tegument 4 EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene ul36 and vzv gene 22) 32292830_f1_12 1710 18281 1002 333 120 −7 Klebsiella pneumoniae Contig508A GTC ORF with score 224 to: (ai:7000810707) (or: Pseudomonas aeruginosa) 15875337_f1_13 1711 18282 915 304 324 −29 Norway spruce Q08632 (sr:,norway spruce:picea excelsa) (ec:1.—.—.—) (de: short-chain type dehydrogenase/reductase,) 12635205_f1_19 1712 18283 519 172 189 −13 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 16835455_f1_24 1713 18284 1071 356 132 −5 Microbacterium X79027 (de:m.ammoniaphilum genes ammoniaphilum marnir and mamim.) 11069780_f1_25 1714 18285 432 143 118 −6 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 13129005_f1_26 1715 18286 1587 528 921 −92 Pseudomonas aeruginosa AF012537 (de:pseudomonas aeruginosa acetyl-coa synthetase gene, partial cds; andarginine and ornithine binding protein (aotj), membrane protein (aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), andargr (argr) genes, complete cds.) ( . . . 10448783_f1_27 1716 18287 1653 550 12711631_f1_35 1717 18288 1737 578 537 −52 Escherichia coli C64923 (cl:hypothetical protein hi0135) 36113908_f1_36 1718 18289 981 326 382 −35 Cyanobacterium syncchocystis S77308 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 16147593_f1_37 1719 18290 204 67 5081466_f1_40 1720 18291 726 241 262 −23 Acinetobacter baumannii CONTIG160 GTC ORF with score 262 to: C (ai:7000762410) (or: Pseudomonas aeruginosa) 178762_f1_42 1721 18292 1755 584 741 −73 Mycobacterium tuberculosis Z84724 (de:mycobacterium tuberculosis h37rv complete genome; segment 21/162.) (nt:rv0418, (mtccy22g10.15), len: 500 aa, lpql,) 33728456_f1_43 1722 18293 522 173 263 −23 Klebsiella pneumoniae Contig560A GTC ORF with score 106 to: (ai:1500692508) (or: Boreogadus saida) (de: boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16805388_f1_44 1723 18294 1482 493 171 −9 Herpes simplex virus AF015297 (de:human herpesvirus 6 (type 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 16895907_f1_49 1724 18295 216 71 152 −10 Escherichia coli P00886 (ec:4.1.2.15) (de:synthetase) (3-deoxy-d-arabino- heptulosonate 7-phosphate synthase)) 30364458_f1_51 1725 18296 1404 467 189 −11 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 30345457_f1_53 1726 18297 441 146 110 −6 Drosophila melanogaster P50887 (sr:,fruit fly) (de:60s ribosomal protein 122) 33706916_f1_57 1727 18298 1281 426 159 −8 Saccharomyces cerevisiae X89715 (sr:baker's yeast) (de: s.cerevisiae aob567, aof1001, aoe110, aoe264 and aoe130 genes.) 11042917_f1_58 1728 18299 255 84 10682080_f1_61 1729 18300 708 235 118 −4 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15093917_f1_63 1730 18301 963 320 486 −46 Moraxella sp. P24640 (ec:3.1.1.3) (de:lipase 3 precursor, (triacylglycerol lipase)) 12708312_f1_64 1731 18302 1287 428 19740681_f1_69 1732 18303 777 258 192 −15 Aspergillus fumigatus Contig2661 GTC ORF with score 192 to: (ai:7000762439) (or: Pseudomonas aeruginosa) 34479192_f1_71 1733 18304 1389 462 1554 −159 Acinetobacter calcoaceticus P94132 (ec:1.5.5.1) (de: dehydrogenase) (electron- transferring-flavoprotein dehydrogenase)) 16423780_f1_81 1734 18305 1623 540 110 −3 Drosophila melanogaster K02620 (sr:d.melanogaster dna, clone tm17) (de:d. melanogaster tropomyosin gene isoform 33 (9b0, exon 10b.) (nt:tropomyosin isoform 34 (9b)) 29428816_f1_86 1735 18306 1545 514 295 −26 Klebsiella pneumoniae Contig522A GTC ORF with score 650 to: (ai:7000788463) (or: Pseudomonas aeruginosa) 33603317_f1_89 1736 18307 1314 437 97 −4 Enterobacter cloacae CONTIG495 GTC ORF with score 105 to: (ai:7000799777) (or: Pseudomonas aeruginosa) 12698906_f1_99 1737 18308 1026 341 150 −7 Microbacterium X79027 (de:m.ammoniaphilum genes ammoniaphilum mamir and mamim.) 13152011_f1_100 1738 18309 459 152 195 −16 Klebsiella pneumoniae Contig226A GTC ORF with score 195 to: (ai:7000762470) (or: Pseudomonas aeruginosa) 26050043_f1_108 1739 18310 1344 447 370 −34 Klebsiella pneumoniae Contig538A GTC ORF with score 507 to: (ai:7000833443) (or: Enterobacter cloacae) 32628291_f1_110 1740 18311 993 330 247 −21 Klebsiella pneumoniae Contig538A GTC ORF with score 287 to: (ai:7000833448) (or: Enterobacter cloacae) 12317786_f1_112 1741 18312 534 177 103 −5 Klebsiella pneumoniae Contig511A GTC ORF with score 93 to: (ai:343484) (or:Pneumocystis carinii) (sr:pneumocystis carinii cdna to mrna) (de: pneumocystis carinii (clone gp22) major surface glyco- protein (msg)mrna, 3′ end.) (nt:‘one of multiple genes encoding the major surface) 2598338_f1_113 1742 18313 819 272 263 −22 African clawed frog S07498 (cl:dermal gland protein apeg: trefoil homology) (sr:, african clawed frog) 15835056_f1_115 1743 18314 405 134 132 −8 Achromobacter A61183 georgiopolitanum 31891416_f1_116 1744 18315 276 91 106 −5 Homo sapiens S16506 (sr:, man) 20900325_f1_118 1745 18316 414 137 171 −13 Klebsiella pneumoniae Contig508A GTC ORF with score 465 to: (ai:7000827259) (or: Enterobacter cloacae) 33597567_f1_119 1746 18317 630 209 137 −10 Acinetobacter baumannii CONTIG174 GTC ORF with score 146 to: C (ai:7000763044) (or: Pseudomonas aeruginosa) 4011541_f1_120 1747 18318 858 285 203 −17 Klebsiella pneumoniae Contig508A GTC ORF with score 203 to: (ai:7000762490) (or: Pseudomonas aeruginosa) 4947706_f1_122 1748 18319 594 197 131 −6 Drosophila melanogaster K02620 (sr:d.melanogaster dna, clone tm17) (de:d. melanogaster tropomyosin gene isoform 33 (9b0, exon 10b.) (nt:tropomyosin isoform 34 (9b)) 5181638_f1_123 1749 18320 318 105 4400203_f1_128 1750 18321 1368 455 313 −28 Enterobacter cloacae CONTIG353 GTC ORF with score 423 to: (ai:7501738653) (or: Klebsiella pneumoniae) 11845890_f1_129 1751 18322 882 293 550 −53 Klebsiella pneumoniae Contig376A GTC ORF with score 550 to: (ai:7000762499) (or: Pseudomonas aeruginosa) 15660425_f1_131 1752 18323 1029 342 134 −6 Plasmodium knowlesi P04922 (sr:nuri,) (de:circumsporozoite protein precursor (cs)) 25598556_f1_132 1753 18324 936 311 338 −31 Enterobacter cloacae CONTIG353 GTC ORF with score 338 to: (ai:7000762502) (or: Pseudomonas aeruginosa) 520316_f1_133 1754 18325 594 197 244 −21 Klebsiella pneumoniae Contig235A GTC ORF with score 245 to: (ai:7000819432) (or: Enterobacter cloacae) 10269817_f1_134 1755 18326 1545 514 105 −3 mice|C57BL/6xCBA/CaJ U46463 (sr:house mouse) (de:mus hybrid musculus glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 1254706_f1_135 1756 18327 423 140 131 −9 Aspergillus fumigatus Contig9906 GTC ORF with score 215 to: (ai:7500759215) (or: Candida albicans) 13145831_f1_139 1757 18328 3558 1185 3198 −9999 Haemophilus influenzae P45128 (de:transcription-repair coupling factor (tref)) 20053193_f1_140 1758 18329 768 255 191 −14 Micrococcus luteus JQ0405 22533330_f1_143 1759 18330 1944 647 251 −21 Klebsiella pneumoniae Contig279A GTC ORF with score 441 to: (ai:7000827322) (or: Enterobacter cloacae) 24730291_f1_144 1760 18331 705 234 1036 −104 Pseudomonas aeruginosa P37452 (ec:3.4.21.88) (de:lexa repressor.) 16056531_f1_154 1761 18332 873 290 375 −35 Enterobacter cloacae CONTIG509 GTC ORF with score 375 to: (ai:7000762524) (or: Pseudomonas aeruginosa) 660202_f1_158 1762 18333 429 142 100 −5 Aspergillus fumigatus Contig4476 GTC ORF with score 149 to: (ai:7000775270) (or: Pseudomonas aeruginosa) 30572955_f1_159 1763 18334 936 311 30360207_f1_162 1764 18335 1206 401 33672783_f1_164 1765 18336 447 148 105 −6 Acinetobacter baumannii CONTIG202 GTC ORF with score 116 to: C (ai:7000762535) (or: Pseudomonas aeruginosa) 21885205_f1_165 1766 18337 873 290 127 −5 Saccharomyces cerevisiae S59310 (mp:13r) 24710007_f1_166 1767 18338 270 89 92 −4 Aspergillus fumigatus Contig10292 GTC ORF with score 229 to: (ai:59485) (or:Saccharomyces cerevisiae) (sr:baker's yeast) (de:s.cerevisiae chromosome ix cosmid 9168.) (nt:mal5, sta1, : 1367, cai: 0.3, amyh yeast p08640) 21586687_f1_168 1768 18339 543 180 97 −2 Homo sapiens Q07283 (sr:,human) (de:trichohyalin) 7300028_f1_169 1769 18340 300 99 174 −13 Enterobacter cloacae CONTIG162 GTC ORF with score 174 to: (ai:7000762539) (or: Pseudomonas aeruginosa) 31458283_f1_176 1770 18341 675 224 104 −4 Aspergillus fumigatus Contig9367 GTC ORF with score 182 to: (ai:99171) (or:Dictyostelium discoideum) (de:dictyostelium discoideum sp96 gene for spore coat protein sp96.) 10828957_f1_197 1771 18342 1011 336 123 −5 Streptomyces coelicolor AL021529 (de:streptomyces coelicolor cosmid 10a5.) (nt:sc10a5.35, possible ntp pyrophospho- hydrolase, len:) 14177205_f1_198 1772 18343 621 206 124 −5 Escherichia coli D90774 (sr:escherichia coli (strain: k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 5213205_f1_208 1773 18344 576 191 97 −5 Enterobacter cloacae CONTIG416 GTC ORF with score 290 to: (ai:7501753985) (or: Klebsiella pneumoniae) 2041390_f1_214 1774 18345 1512 503 653 −64 Neisseria gonorrhoeae AF071224 (de:neisseria gonorrhoeae penicillin binding protein 3 (pbp3) gene, complete cds.) (nt:pbp3) 12288968_f1_221 1775 18346 225 74 153 −11 Escherichia coli X70111 (de:e.coli rmf gene for ribosome modulation factor.) 32147833_f1_222 1776 18347 1272 423 275 −24 Klebsiella pneumoniae Contig450A GTC ORF with score 432 to: (ai:7000820977) (or: Enterobacter cloacae) 2526436_f1_223 1777 18348 429 142 142 −8 Acanthamoeba castellanii AF085185 (de:acanthamoeba castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 10241641_f1_224 1778 18349 3111 1036 35829128_f1_234 1779 18350 420 139 114 −7 longfin squid S56117 (sr:, longfin squid) 11213191_f1_262 1780 18351 1824 607 1729 −178 Escherichia coli P75776 (de:hypothetical abc transporter atp-binding protein ybhf) 16288330_f1_264 1781 18352 1158 385 756 −75 Escherichia coli P75774 (de:hypothetical 41.6 kd protein in moae-rhle intergenic region) 12195758_f1_265 1782 18353 1122 373 333 −30 Pseudomonas aeruginosa X99514 (fn:outer membrane component of multidrug efflux) (de:p.aeruginosa mexc, mexf & oprn genes.) 31765807_f1_266 1783 18354 1452 483 676 −66 Vibrio cholerae AB012956 (sr:vibrio cholerae (str:mo45) dna) (de:vibrio cholerae genes for o-antigen synthesis, strain mo45, complete cds.) (nt:unknown) 12761316_f1_274 1784 18355 576 191 107 −6 Enterobacter cloacae CONTIG500 GTC ORF with score 107 to: (ai:7000723201) (or:no gb taxonomy match) (de:human papillomavirus type 80 e6, e7, e1, e2, e4, 12, and 11 genes.) (nt:putative) 29942291_f2_284 1785 18356 1194 397 681 −67 Bacillus megaterium AJ000758 (fn:involved in cobalamin synthesis) (de:bacillus megaterium 16kb genomic sequence, cobalamin operon.) 16885780_f2_287 1786 18357 402 133 191 −15 Enterobacter cloacae CONTIG304 GTC ORF with score 270 to: (ai:7501734140) (or: Klebsiella pneumoniae) 13089787_f2_288 1787 18358 639 212 146 −8 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35276056_f2_289 1788 19359 261 86 124 −7 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33698782_f2_291 1789 18360 294 97 107 −5 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de: human mucin-2 gene, partial cds.) 525656_f2_292 1790 18361 951 316 510 −49 Rhodobacter capsulatus AF010496 (de:rhodobacter capsulatus strain sb1003, partial genome.) 11175812_f2_294 1791 18362 1152 383 123 −5 Homo sapiens U82987 (sr:human) (de:human bcl-2 binding component 3 (bbc3) mrna, partial cds.) (nt:bbc3; approximately 500 base pairs missing from 5′ 10605140_f2_297 1792 18363 813 270 123 −4 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 14929081_f2_301 1793 18364 1224 407 164 −10 Enterobacter cloacae CONTIG486 GTC ORF with score 304 to: (ai:7000797020) (or: Pseudomonas aeruginosa) 36510461_f2_304 1794 18365 3096 1031 668 −65 Escherichia coli P39182 (de:histidine-binding periplasmic protein precursor (hbp)) 31344137_f2_305 1795 18366 1401 466 829 −83 Escherichia coli P20091 (de:histidine transport system permease protein hism) 34614217_f2_309 1796 18367 207 68 94 −5 Aspergillus fumigatus Contig4048 GTC ORF with score 145 to: (ai:380588) (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem- 11 (stratagene)) bloo) (de: human mucin-2 gene, partial cds.) 30707291_f2_311 1797 18368 441 146 117 −6 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 24506965_f2_315 1798 18369 1020 339 459 −43 Pseudomonas aeruginosa S12643 22307066_f2_317 1799 18370 1164 387 1016 −102 Pseudomonas putida S64687 35628330_f2_321 1800 18371 687 228 103 −3 Orf virus D34768 36067068_f2_322 1801 18372 348 115 24691283_f2_334 1802 18373 759 252 109 −4 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna, completecds.) 16126456_f2_337 1803 18374 987 328 114 −4 Pseudomonas alcaligenes U84154 (de:pseudomonas alcaligenes insertion sequence is1491 putativetransposase subunit genes, complete cds.) 16605040_f2_338 1804 18375 2586 861 3167278_f2_339 1805 18376 1353 450 139 −5 Alphaherpesvirus pseudo- P11675 (sr:indiana-funkhauser/becker, rabies virus PRV prv) (de:immediate-early protein ie180) 10680166_f2_345 1806 18377 1119 372 677 −66 Rhodobacter capsulatus AF010496 (ec.2.1.1.—) (de:rhodobacter capsulatus strain sb1003, partial genome.) 3223437_f2_352 1807 18378 978 325 274 −24 Aspergillus fumigatus Contig2004 GTC ORF with score 274 to: (ai:7000762722) (or: Pseudomonas aeruginosa) 33409713_f2_356 1808 18379 447 148 115 −7 longfin squid S56117 (sr:, longfin squid) 16511562_f2_358 1809 18380 516 171 138 −8 Saccharomyces cerevisiae P47179 (sr:,baker's yeast) (de: precursor) 103527_f2_364 1810 18381 1368 455 388 −36 Methanobacterium G69051 thermoautotrophicum 4305406_f2_365 1811 18382 837 278 558 −54 Pseudomonas aeruginosa L42622 (sr:pseudomonas aeruginosa (strain pao1) dna) (de: pseudomonas aeruginosa pilz and holb genes, complete cds.) (nt:orf3) 4428802_f2_368 1812 18383 684 227 93 −2 Klebsiella pneumoniae Contig168A GTC ORF with score 93 to: (ai:7000762738) (or: Pseudomonas aeruginosa) 3152336_f2_373 1813 18384 753 250 138 −9 Staphylococcus epidermidis CONTIG081 GTC ORF with score 138 to: C (ai:7000762743) (or: Pseudomonas aeruginosa) 12292681_f2_377 1814 18385 930 309 160 −8 equine herpesvirus type 1 D88734 (sr:equine herpesvirus 1 EVH-1 (strain:bk343, isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glyco- protein, complete cds.) 445818_f2_381 1815 18386 642 213 119 −4 Alphaherpesvirus pseudo- S04713 (cl:herpesvirus immediate- rabies virus PRV early protein ie175) 6103838_f2_387 1816 18387 3228 1075 2003 −207 Escherichia coli P21513 (ec:3.1.4.—) (de:ribonuclease c, (rnase c)) 26265638_f2_389 1817 18388 993 330 96 −2 Volvox carteri S22697 10260293_f2_390 1818 18389 510 169 105 −3 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 21502067_f2_394 1819 18390 1521 506 99 −3 Enterobacter cloacae CONTIG292 GTC ORF with score 489 to: (ai:236122) (or:Escherichia coli) (sr:escherichia coli dna) (de:escherichia coli tolqra gene cluster dna.) (nt:orf 4; putative) 14348936_f2_395 1820 18391 2112 703 252 −18 Canadian hard winter wheat B30843 (cl:glutenin) (sr:, common wheat) 33618776_f2_400 1821 18392 1989 662 280 −24 Klebsiella pneumoniae Contig508A GTC ORF with score 364 to: (ai:7000763040) (or: Pseudomonas aeruginosa) 32166456_f2_407 1822 18393 1122 373 417 −39 Klebsiella penumoniae Contig376A GTC ORF with score 550 to: (ai:7000762499) (or: Pseudomonas aeruginosa) 14978401_f2_410 1823 18394 270 89 223 −19 Klebsiella pneumoniae Contig376A GTC ORF with score 577 to: (ai:7000819414) (or: Enterobacter cloacae) 33792208_f2_411 1824 18395 525 174 138 −10 Enterobacter cloacae CONTIG353 GTC ORF with score 138 to: (ai:7000762781) (or: Pseudomonas aeruginosa) 21886525_f2_413 1825 18396 405 134 113 −7 Enterobacter cloacae CONTIG353 GTC ORF with score 113 to: (ai:7000762783) (or: Pseudomonas aeruginosa) 13800830_f2_422 1826 18397 450 149 116 −6 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 650256_f2_425 1827 18398 633 210 17031917_f2_433 1828 18399 2541 846 733 −73 Klebsiella pneumoniae Contig559A GTC ORF with score 733 to: (ai:7000762803) (or: Pseudomonas aeruginosa) 33864417_f2_438 1829 18400 1293 430 231 −19 Coxiella burnetii P45680 (de:hypothetical 15.8 kd protein in fmu-rpmh intergenic region) 11895933_f2_444 1830 18401 2505 834 98 −4 Homo sapiens I39004 (sr:, man) (mp:9p21-9p21) 29429068_f2_449 1831 18402 432 143 130 −8 Volvox carteri S22697 31673956_f2_450 1832 18403 1656 551 15034706_f2_459 1833 18404 1098 365 328 −29 Pseudomonas aeruginosa U73506 (de:pseudomonas aeruginosa ornithine utilization regulatory (orur)gene, complete cds.) (nt: regulatory locus for ornithine utilization) 32546958_f2_463 1834 18405 456 151 177 −14 Klebsiella pneumoniae Contig525A GTC ORF with score 177 to: (ai:7000762833) (or: Pseudomonas aeruginosa) 19777080_f2_464 1835 18406 636 211 1050 −106 Pseudomonas aeruginosa AF053982 (de:pseudomonas aeruginosa putative molybdoterin-guanine dinucleotidebiosynthesis protein a (moba) and cytochrome c precursor protein(snr1) genes, complete cds; and unknown genes.) 1253541_f2_465 1836 18407 861 286 783 −78 Pseudomonas aeruginosa AF053982 (de:pseudomonas aeruginosa putative molybdoterin-guanine dinucleotidebiosynthesis protein a (moba) and cytochrome c precursor protein(snr1) genes, complete cds; and unknown genes.) 32449068_f2_467 1837 18408 531 176 107 −4 Homo sapiens M13228 (sr:human la-n-5 neuro- blastoma cell dna; clone n- myc1) (de:human n-myc oncogene protein mrna.) (nt: n-myc protein) 11223577_f2_471 1838 18409 1506 501 36041375_f2_473 1839 18410 1362 453 156 −7 Homo sapiens Q07283 (sr:,human) (de:trichohyalin) 3339181_f2_478 1840 18411 345 114 155 −11 Escherichia coli P42617 (de:hypothetical 11.1 kd protein in exur-tdcc intergenic region) 26056533_f2_479 1841 18412 384 127 124 −8 Escherichia coli P42618 (de:hypothetical 15.1 kd protein in exur-tdcc intergenic region) 36114383_f2_481 1842 18413 1392 463 729 −72 Cyanobacterium synechocystis S76527 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 33708152_f2_497 1843 18414 450 149 139 −10 Klebsiella pneumoniae Contig450A GTC ORF with score 139 to: (ai:7000762867) (or: Pseudomonas aeruginosa) 16135080_f2_498 1844 18415 483 160 109 −7 Aspergillus fumigatus Contig9443 GTC ORF with score 109 to: (ai:7000762868) (or: Pseudomonas aeruginosa) 12366327_f2_499 1845 18416 2055 684 197 −15 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 150/162.) (nt:rv3569c, (mtcy06g11.16c), len: 291. probable) 31349016_f2_509 1846 18417 1023 340 102 −2 Alphaherpesvirus pseudo- S04713 (cl:herpesvirus immediate- rabies virus PRV early protein ie175) 6519791_f2_511 1847 18418 1536 511 109 −2 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 26267643_f2_515 1848 18419 519 172 129 −8 Medicago sativa Y16672 (de:medicago sativa mrna for putative arginine/serine- rich splicingfactor.) 11041531_f2_517 1849 18420 990 329 157 −8 Saccharomyces cerevisiae P08640 (sr:,baker's yeast) (ec:3.2.1.3) (de:glucosidase) (1,4-alpha-d- glucan glucohydrolase)) 32558336_f2_520 1850 18421 1236 411 14972715_f2_524 1851 18422 927 308 157 −11 Aquifex aeolicus F70487 34244831_f2_532 1852 18423 669 222 178 −14 Klebsiella pneumoniae Contig525A GTC ORF with score 178 to: (ai:7000762902) (or: Pseudomonas aeruginosa) 9852000_f2_545 1853 18424 1335 444 174 −11 Helicobacter pylori F64606 17039705_f3_561 1854 18425 429 142 126 −7 Pseudomonas aeruginosa P15276 (de:algr3)) 12391418_f3_562 1855 18426 546 181 102 −3 Caenorhabditis elegans Z83107 (de:caenorhabditis elegans cosmid f32a7, complete sequence.) (nt:predicted using genefinder; similar to claustrin) 4895958_f3_566 1856 18427 2247 748 132 −5 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 12508506_f3_569 1857 18428 906 301 159 −8 Micrococcus luteus JQ0405 16192931_f3_570 1858 18429 1110 369 536 −51 Pseudomonas aeruginosa AF055999 (de:pseudomonas aeruginosa hemin uptake locus, hypo- thetical proteinphuw (phuw), atpase component (phuv), abc-type permease (phuu), periplasmic binding protein (phut), hemin degrading factor (phus), and outer membrane hemin receptor (ph . . . 13067826_f3_574 1859 18430 507 168 92 −2 rainbow trout Q04617 (sr:,rainbow trout:salmo gairdneri) (de:corticotropin- lipotropin a precursor (pro- opiomelanocortin) (pomc)) 12364505_f3_577 1860 18431 1002 333 101 −5 longfin squid S56117 (sr:, longfin squid) 3260458_f3_578 1861 18432 1200 399 199 −12 equine herpesvirus type 1 D88733 (sr:equine herpesvirus 1 EVH-1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 7227061_f3_581 1862 18433 1290 429 862 −86 Campylobacter jejuni P45493 (ec:3.5.1.32) (de:- (hippuricase)) 31897556_f3_583 1863 18434 417 138 105 −5 Cyanobacterium synechocystis S76563 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 29949057_f3_584 1864 18435 834 277 742 −73 Escherichia coli P52094 (de:histidine transport system permease protein hisq) 36501018_f3_585 1865 18436 867 288 106 −3 Globodera pallida X96713 (de:g.pallida mrna for collagen.) (nt:putative) 15908516_f3_587 1866 18437 1293 430 116 −4 Trypanosoma cruzi A40215 31382308_f3_588 1867 18438 1113 370 163 −9 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16922580_f3_593 1868 18439 1500 499 104 −5 Klebsiella pneumoniae Contig386A GTC ORF with score 104 to: (ai:7000762963) (or: Pseudomonas aeruginosa) 2601002_f3_596 1869 18440 615 204 13142956_f3_597 1870 18441 1965 654 252 −18 Oryctolagus cuniculus P16230 (sr:,rabbit) (de:precursor (hcp)) 30708336_f3_598 1871 18442 276 91 22136006_f3_600 1872 18443 765 254 166 −10 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 1430216_f3_601 1873 18444 1680 559 196 −15 Klebsiella pneumoniae Contig347A GTC ORF with score 349 to: (ai:7000795297) (or: Pseudomonas aeruginosa) 26303933_f3_602 1874 18445 483 160 113 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 36458456_f3_603 1875 18446 1506 501 12995816_f3_604 1876 18447 1272 423 712 −70 Escherichia coli P00888 (ec:4.1.2.15) (de:synthetase) (3-deoxy-d-arabino- heptulosonate 7-phosphate synthase)) 675808_f3_605 1877 18448 402 133 111 −5 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 33869416_f3_606 1878 18449 615 204 117 −4 Caenorhabditis elegans AF000298 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 16208412_f3_608 1879 18450 2016 671 134 −8 Enterobacter cloacae CONTIG450 GTC ORF with score 220 to: (ai:7501795304) (or: Klebsiella pneumoniae) 13089787_f3_609 1880 18451 1107 368 14188331_f3_610 1881 18452 501 166 171 −13 Pseudomonas denitrificans P21635 (de:code protein) 3256891_f3_611 1882 18453 1104 367 112 −3 Trypanosoma cruzi A44937 (cl:kinetoplast-associated protein) 33478158_f3_616 1883 18454 1005 334 458 −43 Acinetobacter calcoaceticus P94132 (ec:1.5.5.1) (de:dehydro- genase) (electron-transferring- flavoprotein dehydrogenase)) 29822506_f3_624 1884 18455 702 233 122 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16538555_f3_628 1885 18456 510 169 104 −4 Homo sapiens AF053536 (sr:human) (de:homo sapiens a-kinase anchoring like protein mrna, complete cds.) (nt:akalp) 7042705_f3_631 1886 18457 1629 542 112 −3 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 3932307_f3_636 1887 18458 867 288 190 −13 Mycobacterium avium AF002133 (de:mycobacterium avium strain gir10 transcriptional regulator (mav81)gene, partial cds, aconitase (acn), invasin 1 (inv1), invasin 2(inv2), transcriptional regulator (moxr), ketoacyl- reductase(fabg), enoyl- reductase (inha) and ferro . . . 15103575_f3_640 1888 18459 201 66 91 −4 Haemophilus influenzae U20229 (de:haemophilus influenzae bola (bola), glutathione reductase (gor), phosphatidyl- serine decarboxylase (psd), 30k protein (rpmf), genes, complete cds.) (nt:orf121) 1277012_f3_642 1889 18460 606 201 570 −55 Escherichia coli P27244 (de:hypothetical 23.2 kd protein in rne-rpmf intergenic region (orfy)) 11175767_f3_652 1890 18461 711 236 254 −21 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12995431_f3_655 1891 18462 636 211 102 −4 Aspergillus fumigatus Contig9346 GTC ORF with score 102 to: (ai:7000763025) (or: Pseudomonas aeruginosa) 29317706_f3_657 1892 18463 477 158 92 −5 Enterobacter cloacae CONTIG470 GTC ORF with score 92 to: (ai:7000763027) (or: Pseudomonas aeruginosa) 12520635_f3_661 1893 18464 636 211 92 −1 mice|C57BL/6xCBA/CaJ AJ001116 (sr:house mouse) (de:mus hybrid musculus mrna for uncx4.1 protein.) 30198417_f3_666 1894 18465 735 244 180 −12 Herpes simplex virus (type 6/ AF015297 (de:human herpesvirus 6 strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate-early 2 protein of human) 16117205_f3_668 1895 18466 540 179 129 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 2616660_f3_669 1896 18467 564 187 152 −11 Cyanobacterium synechocystis S76054 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 22551030_f3_670 1897 18468 1320 439 364 −34 Klebsiella pneumoniae Contig508A GTC ORF with score 364 to: (ai:7000763040) (or: Pseudomonas aeruginosa) 22469466_f3_671 1898 18469 459 152 207 −17 Klebsiella pneumoniae Contig508A GTC ORF with score 207 to: (ai:7000763041) (or: Pseudomonas aeruginosa) 10944462_f3_674 1899 18470 717 238 100 −2 Collectotrichum L76169 (sr:collectotrichum gloeosporioides gloeosporioides (individual_isolate 21808, strai) (de:colletotrichum gloeosporioides reverse transcriptase gene, 3′ endof cds.) (nt:orf2) 33775958_f3_677 1900 18471 1173 390 268 −23 Bacillus subtilis/Bacillus P54527 (de:hypothetical 270.0 kd globigii protein in spo0a-mmga intergenic region) 2438933_f3_678 1901 18472 1779 592 354 −32 Klebsiella pneumoniae Contig441A GTC ORF with score 662 to: (ai:7000835900) (or: Enterobacter cloacae) 6742816_f3_679 1902 18473 1095 364 130 −6 Enterobacter cloacae CONTIG343 GTC ORF with score 130 to: (ai:7000763049) (or: Pseudomonas aeruginosa) 16697812_f3_688 1903 18474 1587 528 178 −12 Aspergillus fumigatus Contig9906 GTC ORF with score 286 to: (ai:7501763937) (or: Klebsiella pneumoniae) 6772636_f3_689 1904 18475 954 317 179 −14 Klebsiella pneumoniae Contig508A GTC ORF with score 341 to: (ai:7000827262) (or: Enterobacter cloacae) 13072766_f3_690 1905 18476 1056 351 144 −7 Homo sapiens P17600 (sr:,human) (de:synapsins ia and ib (brain protein 4.1)) 36070216_f3_691 1906 18477 1164 387 97 −2 mice|C57BL/6xCBA/CaJ Q60987 (sr:,mouse) (de:transcription hybrid factor bf-1 (brain factor 1) (bf1)) 32713278_f3_696 1907 18478 291 96 116 −7 Klebsiella pneumoniae Contig550A GTC ORF with score 116 to: (ai:7000763066) (or: Pseudomonas aeruginosa) 25864503_f3_700 1908 18479 576 191 137 −9 Enterobacter aerogenes P08848 (sr:,aerobacter aerogenes) (de:cell division inhibitor) 32520308_f3_709 1909 18480 3546 1181 973 −98 Klebsiella pneumoniae Contig534A GTC ORF with score 973 to: (ai:7000763079) (or: Pseudomonas aeruginosa) 2817790_f3_716 1910 18481 2169 722 193 −14 Pseudomonas aeruginosa JQ0133 35806528_f3_717 1911 18482 1932 643 813 −81 Escherichia coli S56616 (cl:soluble lytic trans- glycosylase) (ec:3.2.1.—) (mp:100 min) 15682058_f3_718 1912 18483 1977 658 31891452_f3_723 1913 18484 471 156 121 −6 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 31895790_f3_724 1914 18485 1908 635 12629456_f3_727 1915 18486 1545 514 186 −14 Enterobacter cloacae CONTIG461 GTC ORF with score 423 to: (ai:7501780823) (or: Klebsiella pneumoniae) 2226376_f3_730 1916 18487 255 84 367 −34 Pseudomonas aeruginosa AF053982 (de:pseudomonas aeruginosa putative molybdoterin-guanine dinucleotidebiosynthesis protein a (moba) and cytochrome c precursor protein(snr1) genes, complete cds; and unknown genes.) 15022137_f3_738 1917 18488 654 217 417 −39 Rhizobium leguminosarum Q52828 (de:gsta protein) 34646026_f3_739 1918 18489 945 314 92 −3 Aspergillus fumigatus Contig6884 GTC ORF with score 92 to: (ai:7000763109) (or: Pseudomonas aeruginosa) 12931277_f3_740 1919 18490 873 290 167 −10 Xanthomonas campestris U70053 (de:xanthomonas campestris gumn, gumo, and gump genes, complete cds.) 21724206_f3_741 1920 18491 1341 446 1071 −108 Pseudomonas putida AF029714 (de:pseudomonas putida repressor (phan), regulatory protein (pham), enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab), 3- hydroxyacyl-coa dehydro- genase (phac), ketothiolase (phad), phenylacetyl-coa ligase (phae), ring- oxidation . . . 29938580_f3_747 1921 18492 450 149 21892961_f3_752 1922 18493 699 232 173 −13 Klebsiella pneumoniae Contig275A GTC ORF with score 199 to: (ai:7000843618) (or: Enterobacter cloacae) 7052083_f3_753 1923 18494 1089 362 173 −13 Klebsiella pneumoniae Contig479A GTC ORF with score 325 to: (ai:7000801275) (or: Pseudomonas aeruginosa) 16041452_f3_763 1924 18495 2475 824 284 −24 Enterobacter cloacae CONTIG334 GTC ORF with score 458 to: (ai:7501749986) (or: Klebsiella penumoniae) 24694567_f3_769 1925 18496 567 188 2603913_f3_773 1926 18497 642 213 132 −8 Klebsiella pneumoniae Contig529A GTC ORF with score 94 to: (ai:200446) (or:Mus musculus) (sr:, house mouse) 14495841_f3_776 1927 18498 900 299 122 −7 Hydra magnipapillata A41132 (cl:unassigned collagens) 10057907_f3_777 1928 18499 321 106 9792667_f3_780 1929 18500 543 180 119 −8 Klebsiella pneumoniae Contig446A GTC ORF with score 134 to: (ai:5500701468) (or:Equine herpesvirus 4) (fn:very large tegument protein) (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene ul36 and vzv gene 22) 10547683_f3_805 1930 18501 1065 354 717 −71 Escherichia coli C64816 20211638_f3_811 1931 18502 1185 394 863 −86 Escherichia coli P75775 (de:hypothetical 42.1 kd protein in moae-rhlc intergenic region) 2558257_f3_813 1932 18503 1338 445 314 −27 Pseudomonas aeruginosa X99514 (fn:outer membrane component of multidrug efflux) (de:p.aeruginosa mexe, mexf & oprn genes.) 16531381_f3_818 1933 18504 954 317 350 −32 Aquifex aeolicus D70462 16276087_f3_827 1934 18505 672 223 24640756_c1_835 1935 18506 954 317 309 −27 Bacillus subtilis/Bacillus I40425 (ec:3.1.1.1) globigii 4382831_c1_836 1936 18507 600 199 35572961_c1_855 1937 18508 330 109 2082711_c1_856 1938 18509 762 253 302 −27 Enterobacter cloacae CONTIG447 GTC ORF with score 302 to: (ai:7000763226) (or: Pseudomonas aeruginosa) 36222655_c1_865 1939 18510 300 99 13172307_c1_870 1940 18511 1188 395 714 −70 Agrobacterium tumefaciens AB006858 (sr:agrobacterium tumefaciens (TI PLASMID PTIBO542) (strain:maff301001) plasmid: pti-sakur) (de:agrobacterium tumefaciens plasmid pti- sakura trai and trb(b, c, d, e, j, k, l, f, g, h and i) genes, complete cds.) (nt:probable conjugal transfer protein) 14272716_c1_873 1941 18512 1239 412 29346031_c1_874 1942 18513 1239 412 171 −11 Agrobacterium tumefaciens AB006858 (sr:agrobacterium tumefaciens (TI PLASMID PTIBO542) (strain:maff301001) plasmid: pti-sakur) (de:agrobacterium tumefaciens plasmid pti- sakura trai and trb(b, c, d, e, j, k, l, f, g, h and i) genes, complete cds.) (nt:probable conjugal transfer protein) 16151716_c1_875 1943 18514 345 114 10838205_c1_877 1944 18515 753 250 133 −6 Volvox carteri S22697 36064783_c1_879 1945 18516 561 186 121 −5 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 32292936_c1_881 1946 18517 1332 443 454 −43 Agrobacterium tumefaciens AB006858 (sr:agrobacterium tumefaciens (TI PLASMID PTIBO542) (strain:maff301001) plasmid: pti-sakur) (de:agrobacterium tumefaciens plasmid pti- sakura trai and trb(b, c, d, e, j, k, l, f, g, h and i) genes, complete cds.) (nt:probable conjugal transfer protein) 33629068_c1_884 1947 18518 501 166 32630406_c1_889 1948 18519 492 163 114 −4 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 14316576_c1_893 1949 18520 1746 581 959 −96 Escherichia coli P05021 (ec:1.3.3.1) (de:(dhodchase)) 4943765_c1_896 1950 18521 432 143 154 −11 Caenorhabditis elegans U55366 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid f41f3.) (nt:similar to cuticle collagen) 11929780_c1_902 1951 18522 1542 513 34425628_c1_904 1952 18523 747 248 617 −60 Bordetella pertussis P16574 (de:virulence factors putative position transcription regulator bvga) 32552308_c1_906 1953 18524 996 331 236 −17 mice|C57BL/6xCBA/CaJ S59856 (cl:collagen alpha 1(i) chain: hybrid fibrillar collagen carboxyl- terminal homology:von willebrand factor type c repeat homology) (sr:, house mouse) 12300707_c1_915 1954 18525 1395 464 668 −67 Methanococcus jannaschii L77117 (de:methanococcus jannaschii section 116 of 150 of the complete genome.) (nt:similar to gb:x75879 sp:p54144 pid: 2299143) 26383586_c1_919 1955 18526 408 135 104 −5 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpes- virus papio brrf2 homolog gene, partial cds, ebnal, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebnal of epstein-bar v . . . 12236683_c1_927 1956 18527 1299 432 157 −7 Acanthamoeba castellanii AF085185 (de:acanthamoeba castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 31275968_c1_932 1957 18528 2439 812 639 −62 Mycobacterium leprae P53435 (ec:1.1.99.5) (de:glycerol-3- phosphate dehydrogenase,) 34104683_c1_938 1958 18529 618 205 152 −10 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 36041716_c1_939 1959 18530 1389 462 144 −6 Pseudomonas aeruginosa Z54213 (de:p.aeruginosa algy gene.) 13021006_c1_944 1960 18531 1701 566 103 −2 Pinctada fucata D86074 (sr:pinctada fucata cdna to mrna) (de:pinctada fucata mrna for insoluble protein, complete cds.) 31926091_c1_945 1961 18532 720 239 6892666_c1_952 1962 18533 402 133 110 −6 Aspergillus fumigatus Contig8029 GTC ORF with score 318 to: (ai:120145) (or:Bos taurus) (sr:, cattle) 31427037_c1_954 1963 18534 699 232 106 −3 mice|C57BL/6xCBA/CaJ A55817 (cl:unassigned ser/thr or tyr- hybrid specific protein kinases: protein kinase homology) (sr:, house mouse) 10680142_c1_958 1964 18535 420 139 106 −5 Chlamydomonas reinhardtii S50755 strain UTEX 1061 14978900_c1_961 1965 18536 249 82 133 −9 Klebsiella pneumoniae Contig559A GTC ORF with score 133 to: (ai:7000763331) (or: Pseudomonas aeruginosa) 32442881_c1_962 1966 18537 567 188 16658261_c1_965 1967 18538 816 271 317 −29 Klebsiella pneumoniae Contig435A GTC ORF with score 386 to: (ai:7000841537) (or: Enterobacter cloacae) 6745642_c1_966 1968 18539 834 277 322 −29 Vibrio parahaemolyticus PC2359 (n:na+/h+ antiporter hypothetical 175 protein) 16917080_c1_967 1969 18540 1200 399 789 −78 Escherichia coli P75949 (de:hypothetical 37.6 kd protein in fhue-ndh intergenic region) 35443780_c1_970 1970 18541 966 321 438 −41 Enterobacter cloacae CONTIG434 GTC ORF with score 1384 to: (ai:7501766959) (or: Klebsiella pneumoniae) 6520831_c1_972 1971 18542 2124 707 666 −66 Enterobacter cloacae CONTIG434 GTC ORF with score 666 to: (ai:7000763342) (or: Pseudomonas aeruginosa) 22838341_c1_973 1972 18543 1149 382 138 −7 mice S50883 (sr:mice macrophage) (de: putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 4765643_c1_974 1973 18544 1419 472 1633 −168 Escherichia coli H64733 (cl:arginine permease) (mp: 2.6 min) 4506433_c1_975 1974 18545 1347 448 1359 −139 Actinobacillus U24492 (de:actinobacillus pleuro- pleuropneumoniae pneumoniae 48 kda outer membrane protein(aopa) gene, complete cds.) (nt:similar to ngra gene of vibrio alginolyticus) 290908_c1_976 1975 18546 1215 404 1392 −142 Vibrio alginolyticus AB008030 (sr:vibrio alginolyticus dna) (de:vibrio alginolyticus genes for na-translocating nadh- quinonereductase complex, nqr operon, complete genome.) (nt:hydrophobic membrane protein with pi 8.14; ngrb.) 21914680_c1_977 1976 18547 1449 482 759 −75 Haemophilus influenzae P43958 (de:hypothetical protein hi0168/169) 17033265_c1_979 1977 18548 1275 424 1586 −163 Haemophilus influenzae D64052 (pn:nadh-quinone reductase beta chain, na+-translocating) 10652016_c1_981 1978 18549 807 268 94 −4 Haemophilus influenzae P43960 (de:hypothetical protein hi0173) 5197540_c1_986 1979 18550 1254 417 385 −35 Haemophilus influenzae P45247 (de:hypothetical abc transporter atp-binding protein hi1549) 11970183_c1_987 1980 18551 1056 351 180 −14 Klebsiella pneumoniae Contig508A GTC ORF with score 180 to: (ai:7000763357) (or: Pseudomonas aeruginosa) 32708527_c1_994 1981 18552 1149 382 727 −72 Haemophilus influenzae P44491 (ec:2.7.1.130) (de:tetra- acyldisaccharide 4′-kinase, (lipid a 4′-kinase)) 6385456_c1_995 1982 18553 987 328 684 −67 Escherichia coli P04951 (ec:2.7.7.38) (de:synthetase) (cmp-2-keto-3- deoxyoctulosonic acid synthetase) (cks)) 16578506_c1_998 1983 18554 501 166 96 −5 Staphylococcus epidermidis CONTIG007 GTC ORF with score 207 to: C (ai:7000811044) (or: Pseudomonas aeruginosa) 9894758_c1_1000 1984 18555 1071 356 199 −12 Herpes simplex virus (type 6/ AF015297 (de:human herpesvirus 6 strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 20125952_c1_1006 1985 18556 693 230 168 −12 Bacillus subtilis/Bacillus G70044 globigii 16831555_c1_1010 1986 18557 189 62 227 −19 Haemophilus influenzae G64051 (cl:escherichia coli ribosomal protein 132) 16103155_c1_1011 1987 18558 1014 337 731 −72 Salmonella choleraesuis AF044668 (fn:putative role in fatty acid serotype typhimurium or phospholipid) (de: salmonella typhimurium (g30k) gene, partial cds; and 50s ribosomalprotein 132 (rpmf), plsx (plsx), 3-oxoacyl- acyl carrier proteinsynthase iii (fabh), malonyl coa-acyl carrier prote . . . 35666015_c1_1012 1988 18559 1044 347 1540 −158 Pseudomonas aeruginosa U91631 (de:pseudomonas aeruginosa plsx protein homolog (plsx) gene, partialcds; and malonyl- coa:acyl carrier protein transacylase (fabd), 3-oxo- acylacyl carrier protein reductase (fabg), acyl carrierprotein (acpp), and 3- oxoacyl-acyl carrier . . . 26370387_c1_1015 1989 18560 1266 421 2119 −219 Pseudomonas aeruginosa U91631 (de:pseudomonas aeruginosa plsx protein homolog (plsx) gene, partialcds; and malonyl- coa:acyl carrier protein transacylase (fabd), 3-oxo- acylacyl carrier protein reductase (fabg), acyl carrierprotein (acpp), and 3- oxoacyl-acyl carrier . . . 4110452_c1_1020 1990 18561 987 328 1445 −148 Pseudomonas aeruginosa P52024 (ec:2.7.7.7) (de:dna poly- merase iii, delta subunit,) 25519512_c1_1021 1991 18562 390 129 617 −60 Pseudomonas aeruginosa L42622 (sr:pseudomonas aeruginosa (strain paol) dna) (de: pseudomonas aeruginosa pilz and holb genes, complete cds.) (nt:involved in bio- genesis of type 4 fimbriae) 11048783_c1_1025 1992 18563 441 146 100 −4 Caenorhabditis elegans U88170 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid c10g11.) (nt:coded for by c. elegans cdna yk65e4.5; coded for by) 2223506_c1_1026 1993 18564 654 217 132 −7 Methanobacterium B69008 thermoautotrophicum 14975792_c1_1028 1994 18565 405 134 105 −4 Saccharomyces cerevisiae P47179 (sr:,baker's yeast) (de: precursor) 26769182_c1_1029 1995 18566 588 195 235 −20 Acinetobacter baumannii CONTIG230 GTC ORF with score 235 to: C (ai:7000763399) (or: Pseudomonas aeruginosa) 22838586_c1_1030 1996 18567 1365 454 132 −8 Aspergillus fumigatus Contig10032 GTC ORF with score 132 to: (ai:7000763400) (or: Pseudomonas aeruginosa) 9948887_c1_1031 1997 18568 930 309 841 −84 Bradyrhizobium japonicum P53575 (de:transfer flavoprotein small subunit) (etfss)) 6056401_c1_1035 1998 18569 1239 412 888 −89 Clostridium acetobutylicum Contig243H GTC ORF with score 888 to: (ai:7000763405) (or: Pseudomonas aeruginosa) 15754152_c1_1047 1999 18570 621 206 125 −6 Haemonchus contortus B44984 (cl:unassigned collagens) 35797931_c1_1057 2000 18571 462 153 107 −5 Acinetobacter baumannii CONTIG180 GTC ORF with score 159 to: C (ai:195953) (or:Homo sapiens) (sr:, man) 4160083_c1_1059 2001 18572 258 85 11198757_c1_1060 2002 18573 993 330 144 −6 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 10441627_c1_1061 2003 18574 732 243 173 −13 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 124/162.) (nt:rv2850c, (mtcy24a1.07), possible) 31274191_c1_1063 2004 18575 417 138 97 −3 Acanthamoeba castellanii P19706 (sr:,amoeba) (de:myosin heavy chain ib (myosin heavy chain il)) 2745830_c1_1064 2005 18576 1644 547 198 −15 Aspergillus fumigatus Contig7828 GTC ORF with score 198 to: (ai:7000763434) (or: Pseudomonas aeruginosa) 12711442_c1_1066 2006 18577 1470 489 124 −7 Acinetobacter baumannii CONTIG160 GTC ORF with score 124 to: C (ai:7000763436) (or: Pseudomonas aeruginosa) 22128143_c1_1070 2007 18578 1767 588 135 −5 Canadian hard winter wheat P10387 (sr:,wheat) (de:glutenin, high molecular weight subunit dy10 precursor) 33792590_c1_1076 2008 18579 513 170 134 −9 Rhodobacter capsulatus P14172 (sr:,rhodopseudomonas capsulata) (de:hypothetical 28.2 kd protein in ampr 5′region) 1276012_c1_1078 2009 18580 1575 524 13016455_c1_1079 2010 18581 1464 487 7166638_c1_1080 2011 18582 231 76 10444533_c1_1081 2012 18583 822 273 93 −1 Mycobacterium smegmatis AF027770 (de:mycobacterium smegmatis iron uptake genes, fxba (fxba) gene, partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf)genes, complete cds.) (nt:similar to membrane b . . . 36369666_c1_1088 2013 18584 843 280 296 −26 Streptomyces coelicolor AL031031 (de:streptomyces coelicolor cosmid 7c7.) (nt:sc7c7.17, possible transcriptional regulatory) 24032001_c1_1090 2014 18585 1002 333 149 −8 Oryza sativa D16685 (sr:oryza sativa (strain aichiasaki) (library: lambda embl3) seedlin) (ec:1.1.1.27) (de:rice gene for lactate dehydrogenase, complete cds.) 34242663_c1_1091 2015 18586 543 180 138 −8 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 4504842_c1_1096 2016 18587 2241 746 120 −3 Chinese oak silkmoth AF083334 (sr:chinese oak silkmoth) (de: antheraca pernyi fibroin gene, complete cds.) 35650276_c1_1098 2017 18588 594 197 562 −54 Escherichia coli P76264 (de:hypothetical 22.1 kd protein in manz-cspc intergenic region) 26666708_c1_1099 2018 18589 1203 400 177 −12 Achromobacter F36145 georgiopolitanum 26032030_c2_1101 2019 18590 1059 352 1391 −142 Klebsiella pneumoniae P13092 (ec:2.7.1.87) (de:phospho- transferase) (sph)) 24042150_c2_1105 2020 18591 450 149 31541261_c2_1112 2021 18592 540 179 16927158_c2_1122 2022 18593 1338 445 29474033_c2_1123 2023 18594 438 145 103 −5 Acinetobacter baumannii CONTIG143 GTC ORF with score 104 to: C (ai:7500720039) (or: Clostridium acetobutylicum) 22829693_c2_1125 2024 18595 552 183 121 −5 Dictyostelium discoideum P36417 (sr:,slime mold) (de:g-box binding factor (gbf)) 11073452_c2_1127 2025 18596 408 135 269 −23 Entamoeba histolytica Y14328 (de:entamoeba histolytica mrna for 3e1 protein.) 30191531_c2_1128 2026 18597 579 192 343 −31 Klebsiella pneumoniae Contig525A GTC ORF with score 497 to: (ai:7000829287) (or: Enterobacter cloacae) 25391652_c2_1131 2027 18598 840 279 148 −9 Klebsiella pneumoniae Contig525A GTC ORF with score 358 to: (ai:7000829290) (or: Enterobacter cloacae) 32445453_c2_1134 2028 18599 945 314 1385 −141 Achromobacter D38633 (sr:pseudomonas sp. (strain: georgiopolitanum kks102) dna) (de: pseudomonas sp. bphr gene for regulatory protein, complete cds.) 15802155_c2_1142 2029 18600 525 174 16229843_c2_1145 2030 18601 2475 824 1231 −125 Agrobacterium tumefaciens P54910 (de:conjugal transfer protein (TI PLASMID PTIBO542) trbe precursor) 25675442_c2_1151 2031 18602 1236 411 353 −32 Plasmid RK2 H44020 16288341_c2_1155 2032 18603 888 295 103 −2 minor jackknife clam L41834 (sr:ensis minor (clone: 1/6) male adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 10054042_c2_1163 2033 18604 297 98 16034388_c2_1166 2034 18605 2337 778 1540 −158 Haemophilus influenzae P44524 (de:hypothetical protein hi0116/115) 25601637_c2_1171 2035 18606 618 205 209 −17 Escherichia coli F65081 31385207_c2_1173 2036 18607 2295 764 1230 −125 Bordetella parapertussis P40330 (ec:2.7.3.—) (de:virulence sensor protein bvgs precursor,) 11880416_c2_1183 2037 18608 1407 468 11072581_c2_1187 2038 18609 1515 504 266 −22 Streptomyces lividans AF072709 (de:streptomyces lividans amplifiable element aud4: putativetranscriptional regulator, putative ferredoxin, putative cytochromep450 oxidoreductase, and putative oxidoreductase genes, completecds; and unknown genes.) (nt:orf2; similar . . . 3183333_c2_1188 2039 18610 285 94 31538516_c2_1195 2040 18611 1545 514 757 −75 Escherichia coli P12281 (de:molybdopterin bio- synthesis moca protein) 16297928_c2_1197 2041 18612 441 146 125 −7 Caenorhabditis elegans P17656 (de:cuticle collagen 2) 31877307_c2_1199 2042 18613 1629 542 723 −73 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 100/162.) (nt:rv2251, (mtv022.01), len: 475. unknown but similar) 35625806_c2_1201 2043 18614 3024 1007 615 −59 Escherichia coli P76407 (de:hypothetical 32.0 kd protein in ogrk-gatr intergenic region) 9782711_c2_1202 2044 18615 837 278 419 −39 Escherichia coli B64835 5992666_c2_1205 2045 18616 2946 981 1613 −166 Escherichia coli P43672 (de:abc transporter atp- binding protein uup) 24885208_c2_1207 2046 18617 492 163 106 −4 Homo sapiens Q16676 (sr:,human) (de:forkhead- related transcription factor 4 (freac-4)) 21696016_c2_1210 2047 18618 2163 720 3176 −9999 Pseudomonas fragi P28793 (ec:4.2.1.17:5.3.3.8:1.1.1.35:- 5.1.2.3) (de:hydroxybutyryl- coa epimerase,)) 25667292_c2_1211 2048 18619 1191 396 1863 −192 Pseudomonas fragi JS0624 (cl:acetyl-coa acetyl- transferase) 13023916_c2_1215 2049 18620 891 296 266 −23 Klebsiella pneumoniae Contig559A GTC ORF with score 266 to: (ai:7000763585) (or: Pseudomonas aeruginosa) 5947942_c2_1218 2050 18621 246 81 3251711_c2_1220 2051 18622 588 195 284 −25 Klebsiella pneumoniae Contig435A GTC ORF with score 284 to: (ai:7000763590) (or: Pseudomonas aeruginosa) 15676066_c2_1227 2052 18623 507 168 101 −4 Aspergillus fumigatus v1x1c353.x GTC ORF with score 355 to: (ai:345414) (or:Arabidopsis thaliana) (sr:thale cress c24) (de:glycine-rich protein {clone atgrp-1} (arabidopsis thaliana, c24,mrna partial, 740 nt).) (nt:this sequence comes from FIG. 3a; atgrp) 13129035_c2_1230 2053 18624 444 147 408 −38 Klebsiella pneumoniae Contig508A GTC ORF with score 408 to: (ai:7000763600) (or: Pseudomonas aeruginosa) 17036290_c2_1231 2054 18625 228 75 171 −13 Enterobacter cloacae CONTIG355 GTC ORF with score 678 to: (ai:7501784160) (or: Klebsiella pneumoniae) 13010216_c2_1232 2055 18626 576 191 149 −9 human herpesvirus type 6 U13194 (fn:transcriptional regulation) HHV-6 (de:human herpesvirus 6 replication origin-binding protein (hdrfo), partial cds, helicase-primase component (hdrf1), virion protein(dhlf1), putative helicase (hdrf2), putative phosphoprotein (edrf1), replica . . . 9824043_c2_1234 2056 18627 1836 611 1458 −149 Streptomyces roseofulvus AF058302 (de:streptomyces roseofulvus frenolicin biosynthetic gene cluster, complete sequence.) (nt:gapx; probably not the g3phd isoform used in) 9800955_c2_1240 2057 18628 327 108 166 −12 Haemophilus influenzae P43957 (de:hypothetical protein hi0167) 24635163_c2_1241 2058 18629 507 168 411 −38 Vibrio alginolyticus S65528 (pn:na+-translocating nadh- quinone reductase, chain gamma) 13172555_c2_1243 2059 18630 714 237 96 −5 Enterobacter cloacae CONTIG484 GTC ORF with score 195 to: (ai:7000788528) (or: Pseudomonas aeruginosa) 13776030_c2_1246 2060 18631 426 141 120 −6 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 10399055_c2_1247 2061 18632 1086 361 656 −64 Haemophilus influenzae P44550 (de:hypothetical lipoprotein hi0172 precursor) 4553568⁻c2_1249 2062 18633 1404 467 2118 −219 Pseudomonas fluorescens U91523 (fn:transfers reducing equivalents between nad and) (de:pseudomonas fluorescens soluble pyridine nucleotide- transhydrogenase (sth) gene, complete cds.) 12365751_c2_1257 2063 18634 498 165 137 −10 Klebsiella pneumoniae Contig508A GTC ORF with score 180 to: (ai:7000763357) (or: Pseudomonas aeruginosa) 32160455_c2_1258 2064 18635 342 113 273 −24 Escherichia coli P75957 (de:hypothetical abc transporter atp-binding protein ycfv) 35755466_c2_1259 2065 18636 1314 437 719 −71 Escherichia coli P75958 (de:hypothetical 45.3 kd protein in mfd-cobb intergenic region) 6251711_c2_1261 2066 18637 1641 546 319 −25 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 32055142_c2_1264 2067 18638 468 155 140 −10 Neisseria gonorrhocae U79563 (de:neisseria gonorrhacae tonb (tonb), exbb (exbb) and exbd (exbd)genes, complete cds.) 5352206_c2_1266 2068 18639 354 117 165 −12 Escherichia coli P75844 (de:hypothetical 6.9 kd protein in msba-kdsb intergenic region) 6303751_c2_1267 2069 18640 447 148 100 −6 Enterobacter cloacae CONTIG470 GTC ORF with score 100 to: (ai:7000763637) (or: Pseudomonas aeruginosa) 35251631_c2_1268 2070 18641 1236 411 665 −65 Escherichia coli L14557 (sr:escherichia coli (strain rdd012) dna) (de:escherichia coli udp-n-acetylpyruvoyl- glucosamine reductase (murb) gene, complete cds, and biotin operon repressor/biotin holoenzyme(bira) gene, 3′ end.) 35286381_c2_1270 2071 18642 759 252 131 −6 Achromobacter A61183 georgiopolitanum 34652153_c2_1273 2072 18643 237 78 31291080_c2_1277 2073 18644 1170 389 391 −38 Rickettsia prowazekii AJ235269 Rickettsia prowazekii strain Madrid E, complete genome. 13144165_c2_1284 2074 18645 1089 362 1216 −124 Pseudomonas aeruginosa U91631 (de:pseudomonas aeruginosa plsx protein homolog (plsx) gene, partialcds; and malonyl- coa:acyl carrier protein transacylase (fabd), 3-oxo- acylacyl carrier protein reductase (fabg), acyl carrierprotein (acpp), and 3- oxoacyl-acyl carrier . . . 4195187_c2_1285 2075 18646 246 81 366 −33 Pseudomonas aeruginosa U91631 (de:pseudomonas aeruginosa plsx protein homolog (plsx) gene, partialcds; and malonyl- coa:acyl carrier protein transacylase (fabd), 3-oxo- acylacyl carrier protein reductase (fabg), acyl carrierprotein (acpp), and 3- oxoacyl-acyl carrier . . . 29801081_c2_1289 2076 18647 801 266 99 −2 Paramecium bursaria U42580 (de:paramecium bursaria Chlorella virus 1 chlorella virus 1, complete genome.) (nt:lys-, pro-rich, papk (10x); similar to wheat pro-,) 12772882_c2_1290 2077 18648 1092 363 625 −61 Escherichia coli P28306 (de:hypothetical 38.2 kd protein in pabc-holb intergenic region) 35282257_c2_1291 2078 18649 828 275 118 −4 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 35667642_c2_1293 2079 18650 861 286 117 −4 Plasmodium cynomolgi P08674 (sr:gombak,) (de: circumsporozoite protein precursor (cs)) 16881590_c2_1296 2080 18651 1125 374 551 −53 Archaeoglobus fulgidus F69413 20173291_c2_1302 2081 18652 447 148 118 −7 longfin squid S56117 (sr:, longfin squid) 1433318_c2_1308 2082 18653 438 145 115 −7 Haemonchus contortus B44984 (cl:unassigned collagens) 11195887_c2_1310 2083 18654 897 298 103 −2 Nephila clavipes U37520 (de:nephila clavipes dragline silk protein spidroin 1 gene, partialcds.) 12777158_c2_1313 2084 18655 1206 401 965 −97 Pseudomonas denitrificans P29937 (de:cobw protein) 12150405_c2_1314 2085 18656 1737 578 322 −28 Cyanobacterium synechocystis S75635 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 16836631_c2_1315 2086 18657 2208 735 183 −10 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:cbna-1 nuclear protein) 14929576_c2_1316 2087 18658 432 143 188 −14 Klebsiella pneumoniae Contig474A GTC ORF with score 523 to: (ai:7000819999) (or: Enterobacter cloacae) 35682666_c2_1317 2088 18659 414 137 157 −12 Klebsiella pneumoniae Contig423A GTC ORF with score 347 to: (ai:7000834638) (or: Enterobacter cloacae) 31751532_c2_1318 2089 18660 1269 422 742 −75 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 124/162.) (nt:rv2850c, (mtcy24a1.07), possible) 25479707_c2_1320 2090 18661 1272 423 788 −78 Bacillus subtilis/Bacillus D70021 globigii 22477087_c2_1326 2091 18662 1548 515 834 −83 Escherichia coli Q46821 (de:hypothetical 54.4 kd protein in kdui-lyss intergenic region) 13125343_c2_1331 2092 18663 513 170 107 −6 Klebsiella pneumoniae Contig475A GTC ORF with score 230 to: (ai:7000796532) (or: Pseudomonas aeruginosa) 4494218_c2_1332 2093 18664 729 242 200 −16 Corynebacterium glutamicum U85507 (de:corynebacterium glutamicum plasmid pxz10145.1 putative replicase (repa), chloramphenicol resistance protein (cmr), and putativetransposase (tnp) genes, complete cds, and complete plasmidsequence.) 4865955_c2_1335 2094 18665 615 204 406 −38 Myxococcus xanthus C55208 11025377_c2_1337 2095 18666 651 216 273 −24 Escherichia coli P27846 (de:hypothetical 22.5 kd protein in recq-pldb intergenic region) 16510030_c2_1339 2096 18667 1023 340 105 −5 Enterobacter cloacae CONTIG419 GTC ORF with score 105 to: (ai:7000763709) (or: Pseudomonas aeruginosa) 10272830_c2_1343 2097 18668 447 148 109 −6 Pyrococcus horikoshii AP000001 (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) 35252188_c2_1345 2098 18669 1065 354 312 −28 Klebsiella pneumoniae Contig338A GTC ORF with score 312 to: (ai:7000763715) (or: Pseudomonas aeruginosa) 33689540_c2_1348 2099 18670 1215 404 142 −9 Rhizobium sp. P55535 (sr:ngr234,) (de:very hypo- thetical 15.3 kd protein y4kg) 14658283_c2_1350 2100 18671 921 306 105 −2 Gallus gallus domesticus X91637 (sr:chicken) (de:g.gallus mrna for brg1 protein.) 12977086_c2_1352 2101 18672 537 178 106 −6 Human adenovirus type 40 U14651 (de:human adenovirus type 40 protein mu precursor and protein viprecursor genes, complete cds.) 16900791_c2_1353 2102 18673 1116 371 145 −7 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpes- virus papio brrf2 homolog gene, partial cds, ebna1, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebna1 of epstein-barr v . . . 35808181_c2_1358 2103 18674 909 302 220 −20 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 31/162.) (nt: rv0634c, (mtcy20h10.15c), len: 237, putative) 16922930_c2_1359 2104 18675 1116 371 163 −8 Trypanosoma cruzi A44937 (cl:kinetoplast-associated protein) 34267643_c2_1361 2105 18676 816 271 138 −6 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 36344718_c3_1370 2106 18677 399 132 672 −66 Klebsiella pneumoniae P13081 (de:bleomycin resistance protein (brp) (c1990 resistance protein)) 22915841_c3_1380 2107 18678 237 78 25785025_c3_1381 2108 18679 444 147 160 −11 Escherichia coli Q00184 (de:trag protein) 3126058_c3_1382 2109 18680 201 66 16289068_c3_1402 2110 18681 2040 679 921 −92 Escherichia coli Q00185 (de:trag protein) 34610251_c3_1407 2111 18682 402 133 141 −10 Rhizobium sp. P55396 (sr:ngr234,) (de:probable conjugal transfer protein trbc) 29932282_c3_1412 2112 18683 2598 865 292 −22 Enterobacter aerogenes U67194 (fn:mating pair formation) (de:enterobacter aerogenes plasmid r751, complete plasmid sequence.) (nt: cleavage point for export signal sequence between) 22345415_c3_1413 2113 18684 729 242 277 −24 Agrobacterium tumefaciens P54914 (de:conjugal transfer protein (TI PLASMID PTIBO542) trbf) 36051036_c3_1416 2114 18685 756 251 102 −3 Burkholderia cepacia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 667956_c3_1418 2115 18686 261 86 33848532_c3_1421 2116 18687 741 246 92 −2 Gallus gallus domesticus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene coding for phosvitin, exons 23 and 24.) 30503782_c3_1423 2117 18688 1158 385 386 −36 Enterobacter cloacae CONTIG500 GTC ORF with score 386 to: (ai:7000763793) (or: Pseudomonas aeruginosa) 13145657_c3_1426 2118 18689 1308 435 131 −5 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpes- virus papio brrf2 homolog gene, partial cds, ben1, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebna1 of epstein-barr v . . . 6511705_c3_1440 2119 18690 1245 414 515716_c3_1442 2120 18691 1536 511 97 −2 Candida albicans CONTIG420 GTC ORF with score 204 to: 7 (ai:184077) (or: Saccharomyces cerevisiae) (sr:baker's yeast) (de: s.cerevisiae ysa1, ssn6, rad16, and lys2 genes.) 34111665_c3_1443 2121 18692 1233 410 5320843_c3_1451 2122 18693 1572 523 1807 −186 Desulfomonile tiedjei AF015192 (de:desulfomonile tiedjei cytochrome c precursor (hsc) gene, completecds.) (nt: 50 kda membrane cytochrome c co-induced with) 12120438_c3_1453 2123 18694 1272 423 872 −87 Pseudomonas aeruginosa AF053982 (de:pseudomonas aeruginosa putative molybdoterin-guanine dinucleotidebiosynthesis protein a (moba) and cyto- chrome c precursor protein (snr1) genes, complete cds; and unknown genes.) 21661651_c3_1458 2124 18695 1206 401 16876037_c3_1460 2125 18696 1221 406 2632183_c3_1462 2126 18697 1632 543 553 −53 Thermoanerobacter AF001974 (fn:atp-dependent phosphoryl- ethanolicus ation of xylulose to) (de: thermoanaerobacter ethanolicus putative trkg gene, partial cds, andputative trka, xylose isomerase (xyla) and xylulose kinase (xylb) genes, complete cds.) (nt: xylb) 1253057_c3_1473 2127 18698 366 121 166 −13 Klebsiella pneumoniae Contig454A GTC ORF with score 310 to: (ai:7000833177) (or: Enterobacter cloacae) 17056280_c3_1476 2128 18699 1368 455 25781331_c3_1477 2129 18700 459 152 16914667_c3_1481 2130 18701 540 179 237 −20 Acinetobacter baumannii CONTIG212 GTC ORF with score 237 to: C (ai:7000763851) (or: Pseudomonas aeruginosa) 16270716_c3_1482 2131 18702 2670 889 3100 −9999 Escherichia coli P06612 (ec:5.99.1.2) (de:(untwisting enzyme) (swivelase)) 241037_c3_1486 2132 18703 858 285 148 −8 Paralvinella grasslei S53787 22163250_c3_1487 2133 18704 411 136 102 −6 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 17/162.) (nt: rv0338c, (mtcy279.05c), len: 882, unknown) 3339700_c3_1489 2134 18705 753 250 493 −47 Pyrococcus horikoshii AP000005 (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 994001-1166000 nt. position (5/7).) (nt:similar to pir: d64307 percent ident: 48.790 in) 26351681_c3_1501 2135 18706 1023 340 253 −22 Enterobacter cloacae CONTIG503 GTC ORF with score 253 to: (ai:7000763871) (or: Pseudomonas aeruginosa) 22516631_c3_1506 2136 18707 1230 409 16589131_c3_1510 2137 18708 993 330 750 −74 Vibrio alginolyticus S65530 (pn:na+-translocating nadh- quinone reductase nqr5) 31267942_c3_1512 2138 18709 1194 397 153 −8 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 32677043_c3_1519 2139 18710 1317 438 752 −74 Escherichia coli P75958 (de:hypothetical 45.3 kd protein in mfd-cobb intergenic region) 14892031_c3_1524 2140 18711 2283 760 799 −79 Neisseria gonorrhoeae P51973 (de:competence protein coma) 32666438_c3_1525 2141 18712 708 235 209 −17 Aquifex aeolicus G70470 16268893_c3_1529 2142 18713 825 274 336 −30 Cyanobacterium synechocystis Q55535 (sr:pcc 6803,) (ec:3.1.3.48) (de:(cc 3.1.3.48)) 15839687_c3_1531 2143 18714 3546 1181 1077 −109 Klebsiella pneumoniae Contig226A GTC ORF with score 1128 to: (ai:7000834222) (or: Enterobacter cloacae) 29492202_c3_1532 2144 18715 981 326 885 −88 Escherichia coli P23851 (de:hypothetical 36.0 kd protein in rne-rpmf intergenic region (orfx)) 36588586_c3_1537 2145 18716 570 189 297 −26 Escherichia coli P14189 (de:hypothetical 19.3 kd protein in rne-rpmf intergenic region (g30k)) 30751540_c3_1538 2146 18717 828 275 104 −3 Plasmodium cynomolgi P08672 (sr:berok,) (de: circumsporozoite protein precursor (cs)) 16148292_c3_1545 2147 18718 909 302 420 −39 Vibrio harveyi Q56693 (ec:4.—.—.—) (de:4-amino- 4-deoxychorismate lyase, (adc lyase)) 31378542_c3_1548 2148 18719 717 238 451 −42 Yersinia pestis AF065312 (de:yersinia pestis hypothetical protein (yceg) gene, partial cds; thymidylate kinase (tmk) gene; complete cds; and putative dnapoly- merase iii delta‘ subunit (holb) gene, partial cds.) 35597942_c3_1550 2149 18720 606 201 110 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 12363936_c3_1552 2150 18721 867 288 642 −63 Escherichia coli P37346 (de:hypothetical 29.8 kd protein in holb-ptsg intergenic region) 22665956_c3_1558 2151 18722 636 211 11926956_c3_1561 2152 18723 468 155 95 −4 Aspergillus gumigatus Contig8591 GTC ORF with score 247 to: (ai:405746) (or:Mus sp.) (sr: mice macrophage) (de: putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 26439757_c3_1562 2153 18724 969 322 1029 −104 Bradyrhizobium japonicum P53573 (de:transfer flavoprotein large subunit) (etfls)) 21765656_c3_1563 2154 18725 1494 497 13145706_c3_1565 2155 18726 645 214 92 −1 halophilic bacterium P29143 (ec:3.4.21.—) (de:halolysin (strain 172P1) precursor.) 15114455_c3_1567 2156 18727 666 221 98 −4 Mycobacterium tuberculosis M15467 (sr:mycobacterium tuberculosis (strain erdman) dna) (de:m.tuberculosis 65 kda antigen (cell wall protein a) gene.) (nt:orf e145; putative) 34463192_c3_1571 2157 18728 357 118 118 −6 Saccharomyces cerevisiae P47179 (sr:,baker's yeast) (de: precursor) 16800833_c3_1572 2158 18729 3378 1125 2675 −278 Pseudomonas denitrificans P29929 (de:cobn protein) 14098958_c3_1575 2159 18730 429 142 95 −5 Aspergillus furnigatus Contig9850 GTC ORF with score 95 to: (ai:7000763945) (or: Pseudomonas aeruginosa) 34573907_c3_1578 2160 18731 1221 406 163 −9 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10027042_c3_1581 2161 18732 576 191 91 −4 Daucus carota var. sativus U47097 (sr:carrot strain=danver half- long) (de:daucus carota glycine-rich protein mrna, somatic embryo clonegea44, partial cds.) 12977030_c3_1584 2162 18733 750 249 120 −6 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome segment 28/162.) (nt: rv0538, (mtcy25d10.17), len: 748, unknown.) 9789080_c3_1585 2163 18734 495 164 13126042_c3_1587 2164 18735 525 174 111 −5 Aspergillus fumigatus Contig10147 GTC ORF with score 245 to: (ai:175201) (or: Chlamydomonas reinhardtii) (de:chlamydomonas reinhardtii vsp-3 mrna, complete cds.) (nt:amino acid feature: rod protein domain. aa 266 . . . ) 16538317_c3_1589 2165 18736 462 153 103 −3 Streptomyces griseus P54742 (ec:2.7.1.—) (de:serine/ threonine protein kinase afsk,) 32683292_c3_1590 2166 18737 1302 433 225 −18 Enterobacter cloacae CONTIG313 GTC ORF with score 225 to: (ai:7000763960) (or: Pseudomonas aeruginosa) 12165968_c3_1594 2167 18738 456 151 107 −6 Klebsiella pneumoniae Contig453A GTC ORF with score 107 to: (ai:7000763964) (or: Pseudomonas aeruginosa) 16688566_c3_(—1595) 2168 18739 603 200 146 −9 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35328933_c3_1604 2169 18740 873 290 319 −29 Enterobacter cloacae CONTIG339 GTC ORF with score 319 to: (ai:7000763974) (or: Pseudomonas aeruginosa) 35682312_c3_1606 2170 18741 900 299 185 −14 Klebsiella pneumoniae Contig519A GTC ORF with score 185 to: (ai:7000763976) (or: Pseudomonas aeruginosa) 16097830_c3_1607 2171 18742 603 200 283 −25 Aspergillus fumigatus Contig6757 GTC ORF with score 283 to: (ai:7000763977) (or: Pseudomonas aeruginosa) 36614683_c3_1609 2172 18743 1026 341 365 −33 Comamonas testosteroni U32622 (fn:putative regulator of tsambcd) (de:comamonas testosteroni tsar (tsar), toluenesulfonatemethyl- monooxygenase oxygenase component (tsam), toluene- sulfonatemethyl-monooxy- genase reductase component (tsab), toluenesulfonatezinc- independent . . . 16818900_c3_1610 2173 18744 1722 573 622 −61 Pseudomonas aeruginosa D50642 (sr:pseudomonas aeruginosa (strain:paol) dna) (de: pseudomonas aeruginosa pcta gene for transducer, complete cds.) (nt:chemotaxis system) 31533465_c3_1612 2174 18745 1086 361 96 −2 Pseudomonas putida X80272 (de:p.putida pprb gene.) 31737717_c3_1613 2175 18746 621 206 173 −13 Bacillus AB015670 (sr:bacillus sp. dna) (de: bacillus sp. genes for cdase, cgtase, mbp and 15 orfs, partial andcomplete cds.) (nt:a2-5a orf2) 29941317_c3_1616 2176 18747 693 230 148 −8 Arabidopsis thaliana AC000098 (sr:thale cress) (de: arabidopsis thaliana chromosome 1 yac yup8h12 complete sequence.) (nt: est gblatts1136 comes from this gene.) 23941542_c3_1617 2177 18748 336 111 100 −3 equine herpesvirus type 4 AF030027 (fn:very large tegument- EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 16283583_c3_1619 2178 18749 480 159 125 −8 Klebsiella pneumoniae Contig519A GTC ORF with score 164 to: (ai:7000769991) (or: Pseudomonas aeruginosa) 35281530_c3_1621 2179 18750 453 150 91 −4 Holothuria tubulosa P14309 (sr:,sea cucumber) (de:sperm- specific protein phi-0) 35286466_c3_1624 2180 18751 981 326 111 −2 Mycobacterium bovis BCG JC4743 (ec:2.3.1.85) 35283541_c3_1626 2181 18752 945 314 202 −14 Klebsiella pneumoniae Contig553A GTC ORF with score 202 to: (ai:7000763996) (or: Pseudomonas aeruginosa) 3242807_f1_7 2182 18753 1557 518 1338 −136 Corynebacterium sp. P40875 (ec:1.5.3.1) (de:sarcosine oxidase beta subunit,) 12995311_f1_8 2183 18754 414 137 260 −22 Corynebacterium sp. Q46336 (sr:p-1,) (ec:1.5.3.1) (de: sarcosine oxidase delta subunit,) 14947525_f1_10 2184 18755 540 179 144 −9 Homo sapicns M74027 (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 10010457_f1_11 2185 18756 408 135 134 −8 Chlamydomonas reinhardtii S50755 strain UTEX 1061 22860841_f1_16 2186 18757 915 304 734 −72 Corynebacterium sp. Q46339 (ec:3.5.1.10) (de:hydrolase)) 31678841_f1_18 2187 18758 804 267 104 −3 southern root-knot nematode S34665 (cl:unassigned collagens) 7117887_f1_19 2188 18759 966 321 331 −30 Escherichia coli P39173 (de:unknown protein from 2d- page (spots t26/pr37)) 33798280_f1_22 2189 18760 2070 689 151 −8 Klebsiella pneumoniae Contig487A GTC ORF with score 567 to: (ai:7000825229) (or: Enterobacter cloacae) 13006966_f1_24 2190 18761 651 216 124 −5 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhy6a u86, region ie-b) 12554553_f1_27 2191 18762 918 305 102 −3 Aspergillus fumigatus Contig243 GTC ORF with score 212 to: (ai:7000707570) (or: Plasmodium yoelii) (de:plasmodium yoelii yoelii crythrocyte binding protein (maebl) gene, complete cds.) (nt:maebl) 14352255_f1_34 2192 18763 486 161 279 −24 Acinetobactcr sp. ADP1 AF009672 (de:acinetobacter sp. adp1 vanillate demethylase region, vanillate demethylase (vanb) and vanillate demethylase (vana) genes, completecds.) (nt:putative acetyl transferase; orf2) 12239757_f1_35 2193 18764 894 297 212 −15 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15729180_f1_39 2194 18765 477 158 111 −6 Enterococcus faecium CONTIG321 GTC ORF with score 227 to: C (ai:7500727678) (or: Clostridium acetobutylicum) 24428181_f1_45 2195 18766 1005 334 615 −60 no gb taxonomy match AF012127 (de:thiobacillus intermedius k12 cbbr, ribulose bisphosphatecarboxylase/ oxygenase form ii (cbbm) and putative calvin cycleprotein (cbbq) genes, complete cds.) (nt:up regulator of cbbm; calvin cycle regulator of the) 23988800_f1_50 2196 18767 1518 505 1213 −123 Pseudomonas aeruginosa AF029673 (ec:1.1.1.49) (de: pseudomonas aeruginosa hexr (hexr), glucose-6-phosphate1- dehydrogenase (zwf), and 2- keto-3-deoxy-6-phospho- gluconatealdolase (cda) genes, complete cds.) 15722255_f1_54 2197 18768 1971 656 5207262_f1_60 2198 18769 2196 731 2446 −254 Serratia marcescens AF028736 (de:serratia marcescens site specific recombinase (xerc) and dnahelicase ii (uvrd) genes, complete cds.) 4883342_f1_62 2199 18770 1560 519 2511 −261 Pseudomonas aeruginosa AF010184 (de:pseudomonas aeruginosa coenzyme a transferase psecoa (psecoa) gene, complete cds.) (nt:located downstream of the a-band polysaccharide) 15839381_f1_68 2200 18771 1449 482 475627_f1_77 2201 18772 996 331 150 −7 Herpes simplex virus AF015297 (de:human herpesvirus 6 (type 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 33792906_f1_78 2202 18773 597 198 146 −10 Pseudomonas aeruginosa A35630 10657205_f1_80 2203 18774 858 285 122 −5 Orgyia pseudotsugata O10341 (sr:,opmnpv) (de:hypothetical multinucleocapsid nuclear 29.3 kd protein (or(92)) polyhedrosis virus OpMNPV 32683258_f1_81 2204 18775 1332 443 34066257_f1_82 2205 18776 801 266 164 −9 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31897931_f1_85 2206 18777 546 181 16136292_f1_89 2207 18778 474 157 112 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15050951_f1_96 2208 18779 789 262 731 −72 Haemophilus influenzae P43932 (de:hypothetical protein hi0056) 103332_f1_104 2209 18780 1887 628 112 −3 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase-binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein,) 20175292_f1_105 2210 18781 690 229 155 −11 Drosophila silvestris AF026507 (ec:3.4.24.64) (de:drosophila silvestris mitochondrial processing protease beta- precursor (beta mpp) gene, nuclear gene encoding mitochondrialprotein, partial cds.) 29947832_f1_106 2211 18782 534 177 99 −2 equine herpesvirus type 1 D88733 (sr:equine herpesvirus 1 EVH-1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 10956437_f1_110 2212 18783 1311 436 2617641_f1_111 2213 18784 1275 424 149 −7 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus or173 homolog gene, complete cds.) (nt:herpes- virus saimiri orf73 homolog) 14105282_f1_113 2214 18785 693 230 319 −28 Escherichia coli C42384 16500840_f1_120 2215 18786 1155 384 95 −2 mice|C57BL/6xCBA/CaJ S22373 (cl:proline-rich protein) (sr:, hybrid house mouse) 33769417_f1_125 2216 18787 1296 431 127 −4 Herpes simplex virus AF015297 (de:human herpesvirus 6 (type 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 13760033_f1_127 2217 18788 1080 359 120 −4 California red abalone AF023459 (sr:california red abalone) (de: haliotis rufescens lustrin a mrna, complete cds.) (nt:extra- cellular matrix protein; modular structure) 19819438_f1_130 2218 18789 1215 404 26259656_f1_131 2219 18790 651 216 522 −50 Escherichia coli P24253 (de:hypothetical gtp-binding protein in pola-hemn intergenic region) 24353826_f1_132 2220 18791 519 172 97 −2 Saccharomyces cerevisiae S51892 (mp:151) 33675917_f1_135 2221 18792 678 225 105 −3 no gb taxonomy match JW0067 6144136_f1_137 2222 18793 882 293 164 −9 Acanthamocba castellanii AF085185 (de:acanthamoeba castellanii myosin-ia(mia) gene, complete cds.) (nt:myosin-i) 12268891_f1_144 2223 18794 531 176 450 −42 Pseudomonas aeruginosa U58365 (sr:pseudomonas aeruginosa strain=pak) (de:pseudomonas aeruginosa in vivo inducible (np20) gene, partial cds.) (nt: in vivo inducible; fur-like protein) 10972907_f1_146 2224 18795 1005 334 717 −71 Escherichia coli P39832 (de:hypothetical 27.8 kd protein in msbb-ruvb intergenic region) 9861390_f1_147 2225 18796 333 110 99 −4 Volvox carteri S22697 22004076_f1_149 2226 18797 1020 339 96 −2 Human cytomegalovirus P09711 (sr:ad169,) (de:hypothetical protein hkrfx (i1i)) 35397766_f1_150 2227 18798 702 233 535 −51 Bacillus subtilis/Bacillus C70020 globigii 36117003_f1_152 2228 18799 543 180 104 −3 Molluscum contagiosum L10127 (sr:molluscum contagiosum virus subtype 1 virus type 1 dna) (de: molluscum contagiosum virus type 1 orf1 and orf2 dna.) (nt: orf17) 5176031_f1_154 2229 18800 333 110 110 −5 equine herpesvirus type 1 P28968 (sr:ab4p,chv-1) (de:glyco- EVH-1 protein x precursor) 30707066_f1_155 2230 18801 756 251 206 −17 Escherichia coli A64843 (cl:hypothetical protein b1011) 16682205_f1_156 2231 18802 450 149 118 −6 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 527091_f1_158 2232 18803 789 262 278 −24 Methylobacterium extorquens U87316 (de:methylobacterium extorquens putative glycerate kinase and pyruvate- kinase (pyka) genes, complete cds.) (nt:orf3; putative) 16931916_f1_162 2233 18804 465 154 174 −13 Klebsiella pneumonia Contig496A GTC ORF with score 313 to: (ai:7000786831) (or: Pseudomonas aeruginosa) 13173255_f1_166 2234 18805 582 193 164 −10 Rattus norvegicus Z78279 (sr:norway rat) (de: r.norvegicus mrna for collagen alpha1 type i.) (nt: type i) 11183306_f1_171 2235 18806 1038 345 96 −3 Enterobacter cloacae CONTIG495 GTC ORF with score 96 to: (ai:7000764167) (or: Pseudomonas aeruginosa) 24089567_f1_173 2236 18807 966 321 100 −2 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf3 homolog gene, complete cds.) (nt:herpesvirus saimiri orf3 homolog) 22554791_f1_174 2237 18808 738 245 169 −13 Enterobacter cloacae CONTIG438 GTC ORF with score 169 to: (ai:7000764170) (or: Pseudomonas aeruginosa) 99132_f1_177 2238 18809 774 257 13007331_f1_179 2239 18810 906 301 173 −13 Klebsiella pneumoniae Contig532A GTC ORF with score 181 to: (ai:7000795298) (or: Pseudomonas aeruginosa) 24335955_f1_185 2240 18811 765 254 221 −18 Escherichia coli E64897 16660831_f1_188 2241 18812 2184 727 35786431_f1_190 2242 18813 237 78 10836657_f1_193 2243 18814 588 195 186 −13 silkworm S74439 (sr:silkworm) (de:silk fibroin heavy chain (3′region) (bombyx mori=silkworms, mrnapartial, 2008 nt).) (nt: this sequence comes from FIG. 1c.) 14331593_f1_194 2244 18815 984 327 153 −8 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved (spacers r or) 13151580_f1_199 2245 18816 744 247 242 −21 Acinetobacter baumannii CONTIG167 GTC ORF with score 242 to: C (ai:7000764195) (or: Pseudomonas aeruginosa) 35838506_f1_201 2246 18817 390 129 149 −11 Klebsiella pneumoniae Contig553A GTC ORF with score 230 to: (ai:7000810813) (or: Pseudomonas aeruginosa) 22088903_f1_203 2247 18818 1380 459 34510056_f1_204 2248 18819 672 223 121 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 2911016_f1_205 2249 18820 954 317 136 −6 Homo sapiens P23246 (sr:,human) (de:ptb-associated splicing factor (psf)) 36040691_f1_206 2250 18821 1311 436 14735191_f1_212 2251 18822 1377 458 22831375_f1_217 2252 18823 1527 508 32635451_f1_223 2253 18824 1323 440 435 −41 Klebsiella pneumoniae Contig480A GTC ORF with score 717 to: (ai:7000832649) (or: Enterobacter cloacae) 22165793_f1_224 2254 18825 897 298 193 −15 Enterobacter cloacae CONTIG466 GTC ORF with score 654 to: (ai:7501757337) (or: Klebsiella pneumoniae) 641416_f1_232 2255 18826 528 175 131 −9 Enterobacter cloacae CONTIG466 GTC ORF with score 502 to: (ai:7501729059) (or: Kiebsiella pneumoniae) 13179180_f1_238 2256 18827 1497 498 341 −31 Enterobacter cloacae CONTIG258 GTC ORF with score 341 to: (ai:7000764234) (or: Pseudomonas aeruginosa) 21891053_f1_239 2257 18828 750 249 143 −10 Enterobacter cloacae CONTIG258 GTC ORF with score 143 to: (ai:7000764235) (or: Pseudomonas aeruginosa) 16932078_f1_241 2258 18829 951 316 105 −2 Saccharomyces cerevisiae P32323 (sr:,baker's yeast) (de:a- agglutinin attachment subunit precursor) 9797083_f1_247 2259 18830 1590 529 2139 −221 Pseudomonas putida P13454 (de:chromosomal replication initiator protein dnaa) 26056542_f1_252 2260 18831 2424 807 3590 −9999 Pseudomonas putida P13364 (ec:5.99.1.3) (de:dna gyrase subunit b,) 31836456_f1_253 2261 18832 273 90 94 −5 Klebsiella pneumoniae Contig434A GTC ORF with score 101 to: (ai:113149) (or:Rhizobium sp.) (sr:rhizobium sp) (de: rhizobium insertion element isr1.) (nt:orf a (aa 1-278)) 16797093_f1_274 2262 18833 1023 340 463 −44 Enterobacter cloacae CONTIG509 GTC ORF with score 1255 to: (ai:7501794485) (or: Kiebsiella pneumoniae) 35432680_f1_282 2263 18834 525 175 335 −30 Escherichia coli P37619 (de:hypothetical 25.3 kd protein in ftsy-nika intergenic region (o221)) 34480217_f2_283 2264 18835 1251 416 33869830_f2_289 2265 18836 945 314 167 −9 Microbacterium X79027 (de:m.ammoniaphilum genes ammoniaphilum mamir and mamim.) 35285458_f2_290 2266 18837 1818 605 142 −9 mice|C57BL/6xCBA/CaJ Q06666 (sr:,mouse) (de:octapeptide- hybrid repeat protein t2) 35808156_f2_292 2267 18838 1482 493 1222 −124 Pseudomonas putida P46154 (ec:1.2.1.46) (de:(fdh) (faldh)) 5338580_f2_298 2268 18839 570 189 186 −15 Aspergillus fumigatus Contig10344 GTC ORF with score 186 to: (ai:7000764294) (or: Pseudomonas aeruginosa) 318451_f2_299 2269 18840 846 281 105 −3 Human papillomavirus P36783 (de:regulatory protein e2) type 14 31848906_f2_302 2270 18841 426 141 113 −5 Rubella virus P08563 (sr:m33,) (de:glycoproteins e1 and e2)) 32507340_f2_303 2271 18842 1470 489 2145 −222 Pseudomonas fluorescens P07346 (ec:4.3.1.1) (de:asparatate ammonia-lyase, (asparatase)) 5960066_f2_309 2272 18843 624 207 117 −5 Aspergillus fumigatus Contig2869 GTC ORF with score 104 to: (ai:5500685970) (or: Caenorhabditis elegans) (de:(sm-dl)) 34486292_f2_310 2273 18844 981 326 156 −11 Klebsiella pneumoniae Contig242A GTC ORF with score 184 to: (ai:7000827084) (or: Enterobacter cloacae) 16253965_f2_320 2274 18845 252 83 99 −5 Klebsiella pneumoniae Contig460A GTC ORF with score 103 to: (ai:7000797662) (or: Pseudomonas aeruginosa) 35260217_f2_322 2275 18846 2343 780 143 −7 Caenorhabditis elegans Z81503 (de:caenorhabditis elegans cosmid f15f7, complete sequence.) (nt:predicted using genefinder; similar to collagen;) 16150087_f2_326 2276 18847 423 140 104 −4 no gb taxonomy match P28284 (sr:type 2/hg52,) (de:trans- acting transcriptional protein icp0 (vmw118 protein)) 21973251_f2_328 2277 18848 2565 854 117 −3 Dictyostelium discoideum P36417 (sr:,slime mold) (de:g-box binding factor (gbf)) 13806915_f2_332 2278 18849 456 151 338 −30 Pseudomonas denitrificans P29939 (de:hypothetical 15.0 kd protein in cobo 3′region (orf6)) 12932040_f2_340 2279 18850 1554 517 26426916_f2_343 2280 18851 1359 452 384 −36 Klebsiella pneumoniae Contig544A GTC ORF with score 488 to: (ai:7000788018) (or: Pseudomonas aeruginosa) 14349156_f2_344 2281 18852 1107 368 288 −26 Enterobacter cloacae CONTIG420 GTC ORF with score 288 to: (ai:7000764340) (or: Pseudomonas aeruginosa) 33711533_f2_348 2282 18853 3135 1044 180 −10 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 16210458_f2_349 2283 18854 306 101 100 −5 Gallus gallus domesticus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene coding for phosvitin, exons 23 and24.) 16119583_f2_351 2284 18855 408 135 109 −5 Caenorhabditis elegans Z75539 (de:caenorhabditis elegans cosmid f28c1, complete sequence.) (nt:predicted using genefinder; cdna est embl: c13354) 22396016_f2_354 2285 18856 402 133 29789757_f2_357 2286 18857 2040 679 239 −16 Homo sapiens Z74616 (sr:human) (de:h.sapiens mrna for prepro-alpha2(i) collagen.) 16980056_f2_358 2287 18858 1725 574 157 −7 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 20425955_f2_359 2288 18859 1584 527 1379 −141 Bacillus subtilis/Bacillus P42308 (de:hypothetical 45.5 kd globigii protein in bgis-katb intergenic region) 29377157_f2_360 2289 18860 990 329 104 −2 equine herpesvirus type 1 D88685 (sr:equine herpesvirus 1 EVH-1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 36620165_f2_364 2290 18861 1767 588 1826 −188 Escherichia coli P32683 (de:hypothetical 59.5 kd protein in meth-pepe intergenic region) 2556450312_f2_365 2291 18862 420 139 91 −4 Aspergillus fumigatus Contig9871 GTC ORF with score 160 to: (ai:58918) (or:Saccharomyces cerevisiae) (mp:14r) 14177158_f2_373 2292 18863 840 279 113 −4 Orf virus D34768 26066066_f2_381 2293 18864 669 222 155 −10 Caenorhabditis elegans Z79694 (de:caenorhabditis elegans cosmid c15a11, complete sequence.) (nt:predicted using genefinder; similar to collagen) 12292716_f2_382 2294 18865 2418 805 2929 −9999 Pseudomonas aeruginosa U97063 (de:pseudomonas aeruginosa algb (algb) gene, partial cds, and histidineprotein kinase (kinb) gene, complete cds.) (nt:kinb) 26649183_f2_386 2295 18866 2139 712 22000752_f2_392 2296 18867 465 154 118 −6 Acanthamoeba castellanii P10569 (sr:,amoeba) (de:myosin ic heavy chain) 7224092_f2_396 2297 18868 306 101 11726015_f2_397 2298 18869 984 327 625 −124 Pseudomonas aeruginosa P29364 (ec:2.7.1.39) (de:homoserine kinase, (hk)) 35782831_f2_405 2299 18870 1326 441 163 −8 Herpes simplex virus AF015297 (de:human herpesvirus 6 (type 6/strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 29775003_f2_406 2300 18871 948 315 109 −4 Aspergillus fumigatus Contig6633 GTC ORF with score 140 to: (ai:7000774632) (or: Pseudomonas aeruginosa) 31892086_f2_407 2301 18872 1038 345 775 −77 Bacillus subtilis/Bacillus D70020 globigii 33681905_f2_409 2302 18873 921 306 581 −56 Helicobacter pylori D64715 13022636_f2_411 2303 18874 666 221 122 −7 Rattus norvegicus B55663 (sr:, norway rat) 36453830_f2_412 2304 18875 1791 596 141 −5 equine herpesvirus type 4 AF030027 (fn:very large tegument EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 16179566_f2_414 2305 18876 1440 479 32675806_f2_417 2306 18877 1806 601 12915791_f2_418 2307 18878 1065 354 247 −21 Acinetobacter baumannii CONTIG174 GTC ORF with score 108 to: C (ai:70006931 15) (or: Bacillus subtilis) fn:unknown de:bacillus subtilis complete genome section 18 of 21: from 3399551 to 3609060. 29850781_f2_423 2308 18879 906 301 862 −86 Escherichia coli P77150 (ec:2.7.1.35) (de: pyridoxamine kinase, (pm kinase)) 33697208_f2_428 2309 18880 573 190 480 −46 Klebsiella pneumoniae Contig487A GTC ORF with score 141 to: (ai:1500696587) (or:Equine herpesvirus 1) (sr:equine herpesvirus 1 (strain:bk343, isolate:3f clone) dna) (de: equine herpesvirus 1 dna for membrane glycoprotein complete cds.) 33863532_f2_438 2310 18881 1377 458 5181958_f2_446 2311 18882 2868 955 526 −50 Escherichia coli P39830 (de:hypothetical 59.4 kd protein in gsk-fsr intergenic region) 5093892_f2_452 2312 18883 1095 364 186 −12 Klebsiella pneumoniae Contig317A GTC ORF with score 354 to: (ai:7000816188) (or: Enterobacter cloacae) 31770767_f2_453 2313 18884 399 132 33712953_#_455 2314 18885 540 179 103 −3 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 36066455_f2_456 2315 18886 405 134 100 −4 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved st: spacers r or) 13005031_f2_458 2316 48887 462 153 142 −10 Enterobacter cloacae CONTIG441 GTC ORF with score 161 to: (ai:7000811178) (or: Pseudomonas aeruginosa) 14198916_f2_459 2317 18888 513 170 152 −11 Enterobacter cloacae CONTIG511 GTC ORF with score 152 to: (ai:7000764455) (or: Pseudomonas aeruginosa) 24735015_f2_463 2318 18889 2046 681 488 −46 Methanobacterium O27199 (ec:3.5.2.3) (de: thermoautotrophicum dihydroorotase, (dhoase)) 16931942_f2_464 2319 18890 543 180 127 −8 Klebsiella pneumoniae Contig523A GTC ORF with score 181 to: (ai:175260) (or:Volvox carteri) 16532207_f2_465 2320 18891 1116 371 186 −11 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene complete cds.) (nt:herpesvirus saimiri orf73 homolog) 7057032_f2_468 2321 18892 204 67 12988532_f2_469 2322 18893 1131 376 203 −14 Klebsiella pneumoniae Contig465A GTC ORF with score 123 to: (ai:7000702062) (de: pseudomonas fluorescens alkaline protease, protease inhibitor,zinc-protease transporter (aprd), zinc- protease transporter (apre), and zinc-protease transporter (aprf) genes. complete cds.) 5181568_f2_470 2323 18894 633 210 305 −27 Caulobacter crescentus AJ010321 (de:caulobacter crescentus partial tig gene and clpp, cica, clpx, longenes.) 31901906_f2_472 2324 18895 1275 424 276 −22 Bacillus subtilis/Bacillus D85082 (sr:bacillus subtilis dna) (de: globigii bacillus subtilis dna, genome sequence, 79 to 81 degree region.) 130239661_f2_473 2325 18896 2172 723 403 −37 Enterobacter cloacae CONTIG466 GTC ORF with score 405 to: (ai:7501757306) (or: Klebsiella pneumoniae) 32241557_f2_481 2326 18897 249 82 312 −28 Enterobacter cloacae CONTIG466 GTC ORF with score 312 to: (ai:7000764477) (or: Pseudomonas aeruginosa) 10728790_f2_483 2327 18898 1773 590 1044 −106 Klebsiella pneumoniae Contig480A GTC ORF with score 1472 to: (ai:7000832653) (or: Enterobacter cloacae) 15760027_f2_485 2328 18899 258 85 97 −5 Klebsiella pneumoniae Contig199A GTC ORF with score 97 to: (ai:7000764481) (or: Pseudomonas aeruginosa) 13016691_f2_486 2329 18900 1068 355 131 −5 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 16064838_f2_490 2330 18901 1233 410 153 −10 Enterobacter cloacae CONTIG258 GTC ORF with score 153 to: (ai:7000764486) (or: Pseudomonas aeruginosa) 10807167_f2_495 2331 18902 369 122 143 −10 Saccharomyces cerevisiae P53071 (sr:,baker's yeast) (de: hypothetical 19.3 kd protein in hap2-ade5,6 intergenic region) 32291316_f2_501 2332 18903 1920 639 463 −44 Klebsiella pseumoniae Contig104A GTC ORF with score 463 to: (ai:7000764497) (or: Pseudomonas aeruginosa) 181532_f2_505 2333 18904 1107 368 1601 −164 Pseudomonas putida P13455 (ec:2.7.7.7) (de:dna poly- merase iii, beta chain,) 14863202_f2_506 2334 18905 1110 369 1561 −160 Pseudomonas putida P13456 (de:recf protein) 22132256_f2_510 2335 18906 537 178 105 −4 Rhizobium sp. P17986 (de:insertion element isr1 hypothetical 30.8 kd protein a) 30335438_f2_523 2336 18907 330 109 93 −3 Oryctolagus cuniculus P55787 (sr:,rabbit) (de:collagen alpha 4 (iv) chain (fragment)) 22058303_f2_524 2337 18908 864 287 340 −31 Klebsiella pneumoniae Contig555A GTC ORF with score 1255 to: (ai:7000844685) (or: Enterobacter cloacae) 35677276_f2_525 2338 18909 1083 360 425 −40 Klebsiella pneumoniae Contig555A GTC ORF with score 1255 to: (ai:7000844685) (or: Enterobacter cloacae) 30759818_f2_529 2339 18910 1527 508 1046 −106 Pseudomonas fluorescens Y14568 (de:pseudomonas fluorescens tag gene and partial glyq, htrb genes.) 6542193_f2_530 2340 18911 351 116 11805193_f3_533 2341 18912 1725 574 1596 −164 Acinetobacter AF073769 (de:acinetobacter radioresistens radioresistens serine hydroxy- methyltransferase (glya)gene, complete cds.) 34238283_f3_534 2342 18913 639 212 95 −1 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 31757938_f3_536 2343 18914 3051 1016 1822 −202 Corynebacterium sp. Q46337 (sr:p-1,) (ec:1.5.3.1) (de: sarcosine oxidase alpha subunit,) 34414562_f3_537 2344 18915 642 213 236 −20 Corynebacterium sp. Q46338 (sr:p-1,) (ec:1.5.3.1) (de: sarcosine oxidase gamma subunit,) 12113558_f3_538 2345 18916 936 311 167 −9 pig roundworm P27393 (sr:,pig roundworm:ascaris lumbricoides) (de:procollagen alpha 2(iv) chain precursor) 17073467_f3_539 2346 18917 630 209 560 −54 Pseudomonas putida A55577 (ec:1.2.1.46) 12673531_f3_542 2347 18918 1470 489 12677055_f3_547 2348 18919 1398 465 1191 −121 Rhizobium meliloti AF031940 (de:sinorhizobium meliloti (megaplasmid pRME41B SYM) alcohol dehydrogenase (adha) gene, completecds.) 32713506_f3_548 2349 18920 1026 341 148 −8 Klebsiella pneumoniae Contig482A GTC ORF with score 172 to: (ai:7000809604) (or: Pseudomonas aeruginosa) 32679218_f3_551 2350 18921 1383 460 142 −6 Saimiriine herpesvirus 2 Q01042 (sr:11,) (de:immediate-early protein) 4589780_f3_552 2351 18922 720 239 179 −14 Klebsiella pneumoniae Contig403A GTC ORF with score 179 to: (ai:7000764548) (or: Pseudomonas aeruginosa) 36036456_f3_554 2352 18923 1671 556 455 −43 Saccharomyces cerevisiae P40586 (sr:,baker's yeast) (de: hypothetical 27.4 kd protein in hyri 3′region) 36072031_f3_555 2353 18924 1341 446 262 −22 Enterobacter cloacae CONTIG433 GTC ORF with score 262 to: (ai:7000764551) (or: Pseudomonas aeruginosa) 16276083_f3_556 2354 18925 2907 968 238 −19 Aspergillus fumigatus Contig1576 GTC ORF with score 238 to: (ai:7000764552) (or: Pseudomonas aeruginosa) 15828528_f3_557 2355 18926 948 315 189 −12 Epstein-Barr virus P03181 (sr:b95-8,human herpesvirus 4) (de:hypothetical bhlf1 protein) 35828216_f3_558 2356 18927 2532 843 139 −5 Canadian hard winter wheat JC2099 (cl:glutenin) (sr:, common wheat) (mp:lb) 13020767_f3_559 2357 18928 1428 475 1806 −186 Escherichia coli P76403 (ec:3.4.—.—) (de:putative protease in bacr-ogrk intergenic region,) 31297667_f3_563 2358 18929 705 234 102 −2 Caenorhabditis elegans Z78418 (de:caenorhabditis elegans cosmid f25d7, complete sequence.) (nt:similar to claustrin like; cdna est cemsh64f comes) 34630392_f3_569 2359 18930 2019 672 180 −10 Acanthamoeba castellanii AF085185 (de:acanthamoeba castellanii myosin-ia (mia) gene, complete cds.) (nt:myosin-i) 14175801 _f3_574 2360 18931 237 78 16819058_f3_578 2361 18932 894 297 171 −10 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31694592_f3_584 2362 18933 840 279 154 −8 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 5953951_f3_590 2363 18934 1791 596 116 −6 Amsacta moorei U30297 (de:amsacta moorei entomopoxvirus entomopoxvirus filament- associated late protein,faipe, complete cds.) (nt:contains 10 repeats of the proline-glutamic acid) 14147555_f3_591 2364 18935 1296 431 16275680_f3_593 2365 18936 2013 670 150 −8 Mycobacterium leprae Z99263 (de:mycobacterium leprae cosmid b637.) (nt: m1cb637.02c, unknown, len: 280 aa; n-terminus has) 11141306_f3_596 2366 18937 426 141 31297656_f3_597 2367 18938 2265 754 22898331_f3_599 2368 18939 1047 348 361 −34 Rickettsia prowazekii AJ235269 Rickettsia prowazekii strain Madrid E, complete genome. 16229566_f3_600 2369 18940 420 139 116 −6 Chlamydomonas eugametos S50754 7320407_f3_604 2370 18941 1059 352 107 −3 Klebsiella pneumoniae Contig316A GTC ORF with score 90 to: (ai:195134) (or:Homo sapiens) (de:human (clone c5.1) mrna-binding protein mrna, complete cds.) (nt: putative) 10633415_f3_61 1 2371 18942 480 159 152 −10 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15757312_f3_613 2372 18943 438 145 134 −9 Aspergillus fumigatus Contig10074 GTC ORF with score 123 to: (ai:82733) (or:Gallus gallus) (sr:gallus gallus (strain white leghorn, sub_species domesticus) (de:gallus gallus domesticus aortic lysyl oxidase mrna, complete cds.) 3332663_f3_614 2373 18944 675 224 14538455_f3_617 2374 18945 519 172 242 −20 Klebsiella pneumoniae Contig557A GTC ORF with score 106 to: (ai:392664) (or:Mus musculus) (sr:house mouse) (de:mus musculus glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 22392283_f3_618 2375 18946 993 330 541 −52 Klebsiella pneumoniae Contig557A GTC ORF with score 106 to: (ai:392664) (or:Mus musculus) (sr:house mouse) (de:mus musculus glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 10802305_f3_622 2376 18947 1251 416 413 −38 Escherichia coli B42384 5194812_f3_626 2377 18948 1359 452 2243 −232 Pseudomonas aeruginosa P23747 (de:alginate biosynthesis transcriptional regulatory protein algb) 11182308_f3_631 2378 18949 1941 646 146 −8 Klebsiella pneumoniae Contig385A GTC ORF with score 146 to: (ai:7000764627) (or: Pseudomonas aeruginosa) 10628830_f3_637 2379 18950 900 299 128 −5 Bos primigenius taurus P02459 (sr:,bovine) (de:collagen alpha 1 (ii) chain (fragments)) 21933543_f3_638 2380 18951 879 292 231 −19 Enterobacter cloacae CONTIG267 GTC ORF with score 231 to: (ai:7000764634) (or: Pseudomonas aeruginosa) 15837768_f3_639 2381 18952 1263 420 214 −17 Klebsiella pneumoniae Contig039A GTC ORF with score 214 to: (ai:7000764635) (or: Pseudomonas aeruginosa) 2527276_f3_640 2382 18953 753 250 141 −8 Enterobacter cloacae CONTIG267 GTC ORF with score 141 to: (ai:7000764636) (or: Pseudomonas aeruginosa) 34464406_f3_642 2383 18954 471 156 468 −44 Pseudomonas aeruginosa P29364 (ec:2.7.1.39) (de:homoserine kinase, (hk)) 5182328_f3_644 2384 18955 2388 795 3185O837_f3_650 2385 18956 870 289 758 −75 Escherichia coli P52648 (de:hypothetical abc transporter atp-binding protein yebm) 21610126_f3_651 2386 18957 1611 536 110 −3 Human papillomavirus Q80910 (de:regulatory protein e2) type 38 14869582_f3_654 2387 18958 786 261 119 −7 Klebsiella pneumoniae Contig357A GTC ORF with score 217 to: (ai:7000814129) (or: Enterobacter cloacae) 11019432_f3_655 2388 18959 1191 396 135 −6 Clostridium perfringens P26833 (de:hypothetical 31.2 kd protein in nagh 5′region (orfb)) 21532906_f3_656 2389 18960 1986 661 443 −43 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 85/162.) (nt: rv1878, (mtcy180.40c), len: 450. glna3, similar to) 12994831_f3_658 2390 18961 1443 480 713 −70 Salmonella choleraesuis X99945 (de:s.typhimunum orf's 32 & serotype typhimurium 48 & gene pykf.) 34503291_f3_659 2391 18962 1473 490 237 −19 Aeromonas hydrophila U56832 (de:aeromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 22160392_f3_665 2392 18963 1119 372 445 −42 Pseudomonas aeruginosa Q00982 (ec:3.5.2.6) (de:beta- lactamase oxa-5 precursor,) 6453531_f3_673 2393 18964 1518 505 21875380_f3_683 2394 18965 816 271 429 −40 Escherichia coli P25716 (ec:1.1.1.100) (de:acyl carrier protein reductase)) 6837651_f3_688 2395 18966 711 236 26053963_f3_689 2396 18967 1623 540 1204 −122 Escherichia coli P17448 (de:alpha-ketoglutarate permease) 6270950_f3_690 2397 18968 1431 476 95 −3 human herpesvirus type 6 S43071 HHV-6 3239581_f3_692 2398 18969 570 189 114 −4 Saccharomyces cerevisiae P08640 (sr:,baker's yeast) (ec:3.2.1.3) (de:glucosidase) (1,4-alpha-d- glucan glucohydrolase)) 26032041_f3_695 2399 18970 1275 424 12615686_f3_696 2400 18971 492 163 22147511_f3_700 2401 18972 447 148 98 −2 infectious bovine rhino- Z78205 (de:bovine herpesvirus type 1 tracheitis virus u122-35 genes.) (nt:very large tegument protein) 3928876_f3_701 2402 18973 1053 350 285 −24 Synechococcus sp. AF015889 (de:synechococcus pcc7002 (strain PCC 7002) carbon dioxide concentrating mechanismproteins (ccmk), (ccml), (ccmm), and (ccmn) genes, complete cds,and ribulose bisphosphate carboxylase/oxygenase large subunit gene partial cds.) (nt:inactivation leads t . . . 32676965_f3_722 2403 18974 222 73 103 −6 Aspergillus famigatus Contig6611 GTC ORF with score 103 to: (ai:7000705864) (or: Mycobacterium tuberculosis) (de:mycobacterium tuberculosis h37rv complete genome; segment 35/162.) (nt: rv0746, (mtv04.20), len: 783. member of pe pgrs) 16066458_f3_724 2404 18975 1416 471 712 −70 Klebsiella pneumoniae Contig480A GTC ORF with score 1173 to: (ai:7000832623) (or: Enterobacter cloacae) 2540627_f3_725 2405 18976 1050 349 393 −37 Klebsiella pneumoniae Contig480A GTC ORF with score 913 to: (ai:7000832653) (or: Enterobacter cloacae) 5192702_f3_729 2406 18977 528 175 179 −14 Enterobacter cloacae CONTIG466 GTC ORF with score 323 to: (ai:7501729055) (or: Klebsiella pneumoniae) 12135443_f3_752 2407 18978 600 199 122 −4 mice|C57BL/6xCBA/CaJ P11087 (sr:,mouse) (de:procollagen hybrid alpha 1(i) chain precursor) 2914131_f3_759 2408 18979 402 133 147 −9 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 3143750_f3_763 2409 18980 999 332 232 −19 Insertion sequence IS476 M28557 (sr:insertion sequence is476 (clone: pxv2m101.) dna) (de: insertion sequence (from x.campestris).) (nt:orf2; putative) 32611540_f3_770 2410 18981 1824 607 250 −35 Rhizobium sp. P55493 (sr:ngr234,) (de:hypothetical 65.5 kd protein y4ij) 13160458_f3_773 2411 18982 480 159 94 −5 Streptococcus pneumoniae CONTIG201 GTC ORF with score 94 to: D (ai:7000764769) (or: Pseudomonas aeruginosa) 33853958_f3_774 2412 18983 483 160 109 −7 Klebsiella pneumoniae Contig555A GTC ORF with score 99 to: (ai:59178) (or:Pseudomonas aeruginosa) (de:algr3)) 31882001_f3_776 2413 18984 420 139 128 −9 Klebsiella pneumoniae Contig027A GTC ORF with score 128 to: (ai:7000764772) (or: Pseudomonas aeruginosa) 32114755_f3_777 2414 18985 666 221 833 −83 (seudomonas fluorescens Y14568 (de:pseudomonas fluorescens tag gene and partial glyq, htrb genes.) 10024131_c1_781 2415 18986 387 128 190 −15 Klebsiella pneumoniae Contig502A GTC ORF with score 425 to: (ai:7000839778) (or: Enterobacter cloacae) 30562543_c1_785 2416 18987 1050 349 1372 −140 Moraxella catarrhalis P77892 (ec:6.1.1.14) (de:alpha chain) (glyrs)) 10975715_c1_790 2417 18988 555 184 131 −7 Cacnorhabditis elegans Z71178 (de:caenorhabditis elegans cosmid b0024, complete sequence.) (nt:similar to collagen) 13087781_c1_797 2418 18989 2841 946 679 −65 Halobacterium sp. AF016485 (de:halobacterium sp. nrc-1 NRC-1 plasmid pnrc100, complete plasmid sequence.) (nt:orf h1186; similar to escherichia coli hepa,) 24714401_c1_801 2419 18990 2070 689 616 −60 Haloferax sp. P21562 (sr:aa 2.2,) (de:hypothetical 80.2 kd protein in the 5′region of gyra and gyrh (orf 4)) 22556525_c1_802 2420 18991 420 139 277 −23 Haloferax sp. P21562 (sr:aa 2.2,) (de:hypothetical 80.2 kd protein in the 5′region of gyra and gyrb (orf 4)) 29775916_c1_807 2421 18992 441 146 92 −2 Saccharomyces cerevisiae P53832 (sr:,baker's yeast) (de: precursor) 10281405_c1_808 2422 18993 1338 445 524 −51 Enterobacter cloacae CONTIG146 GTC ORF with score 608 to: (ai:7501797703) (or: Klebsiella pneumoniae) 10019756_c1_811 2423 18994 219 72 201 −16 Pseudomonas putida P16498 (de:50s ribosomal protein 134) 32506391_c1_815 2424 18995 1788 595 2765777_c1_818 2425 18996 1950 649 2961 −9999 Pseudomonas putida P25756 (de:glucose inhibited division protein a) 10979056_c1_820 2426 18997 213 70 223 −18 Pseudomonas putida P31856 (de:hypothetical 28.9 kd protein in gidb-unci intergenic region) 4550943_c1_821 2427 18998 882 293 1158 −117 Pseudomonas putida P31857 (de:hypothetical 32.4 kd protein in gidb-unci intergenic region) 13760056_c1_823 2428 18999 348 115 331 −30 Vibrio alginolyticus P12991 (ec:3.6.1.34) (de:(dicyclo- hexylcarbodiimide-binding protein)) 24725966_c1_824 2429 19000 498 165 461 −44 Vibrio alginolyticus P12989 (ec:3.6.1.34) (de:atp synthase b chain,) 4167168_c1_834 2430 19001 435 144 378 −35 Escherichia coli B90106 (pn:h+-transporting atp synthase, epsilon chain: hydrogen ion-transporting atpase epsilon chain) (cl: h+-transporting atp synthase epsilon chain) (ec: 3.6.1.34) (mp:84 min) 14741431_c1_835 2431 19002 1389 462 1280 −130 Escherichia coli P17114 (ec:2.7.7.23) (de: acetylglucosamine-1- phosphate uridyltransferase)) 475781 _c1_838 2432 19003 390 129 100 −4 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 33855041_c1_842 2433 19004 507 168 90 −4 Aspergillus famigatus Contig8831 GTC ORF with score 93 to: (ai:7000740656) (or: Enterococcus faecium) 12586581_c1_847 2434 19005 438 145 106 −6 Homo sapiens 153641 (sr:, man) (mp:11p15.5-11p15.5) 34241630_c1_850 2435 19006 1044 347 558 −54 Archaeoglobus fulgidus C69329 35832083_c1_853 2436 19007 1383 460 450 −42 Achromobacter D10678 (sr:pseudomonas sp. (strain: georgiopolitanum nk87) plasmid:pnad2 dna) (ec: 3.5.1.46) (de:pseudomonas sp. plasmid pnad2 gene for 6- aminohexanoate-dimer- hydrolase, complete cds.) 492665_c1_860 2437 19008 1224 407 531 −51 Escherichia coli Q46929 (ec:3.5.1.28) (de:n- acetylmuramoyl-1-alanine amidase amic precursor,) 24879706_c1_862 2438 19009 597 198 100 −4 Aspergillus fumigatus Contig159S GTC ORF with score 115 to: (ai:380588) (or:Homo sapiens) (sr:homo sapiens (tissue library:lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 25602041_c1_865 2439 19010 714 237 16015706_c1_869 2440 19011 732 243 126 −5 Molluscum contagiosum L10127 (sr:molluscum contagiosum virus subtype 1 virus type 1 dna) (de: molluscum contagiosum virus type 1 orf1 and orf2 dna.) (nt:orf17) 14183456_(‘3)c1_877 2441 19012 1317 438 34494430_c1_883 2442 19013 273 90 90 −3 Heterodera glycines AF092449 (de:heterodera glycines mucin-like protein (svg 1) mrna, complete cds.) 15673781_c1_884 2443 19014 1476 491 746 −74 Escherichia coli P78061 (ec:6.3.1.2)(de:ligase)) 12272701_c1_885 2444 19015 1452 483 26301563_c1_888 2445 19016 2016 671 1715 −176 Escherichia coli P39830 (de:hypothetical 59.4 kd protein in gsk-tsr intergenic region) 32626441_c1_900 2446 19017 654 217 109 −4 Arancus diadematus U47853 (de:araneus diadematus fibroin-1 (adf-1) mrna, partial cds.) 6495838_c1_901 2447 19018 852 283 139 −7 Caenorhabditis elegans Z49131 (de:caenorhabditis elegans cosmid zc373, complete sequence.) (nt:simiiar to cuticular collagen; cdna est embl:d66257) 12552306_c1_907 2448 19019 708 235 100 −3 Enterobacter cloacae CONTIG424 GTC ORF with score 700 to: (ai:7501742805) (or: Klebsiella pneumoniae) 10417706_c1_913 2449 19020 519 172 301 −27 Klebsiella pneumoniae Contig486A GTC ORF with score 301 to: (ai:7000764909) (or: Pseudomonas aeruginosa) 9853791_c1_915 2450 19021 729 242 373 −35 Enterococcus faecium CONTIG433 GTC ORF with score 110 to: C (ai:7500982114) (or: Pyrococcus horikoshii) (sr: pyrococcus horikoshii (str:ot3) dna, cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) 13022931_c1_918 2451 19022 915 304 116 −3 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 31897842_c1_920 2452 19023 1539 512 574 −56 Escherichia coli P39172 (de:31.1 kd protein in msbb- ruvb intergenic region precursor) 12292003_c1_922 2453 19024 1008 335 111 −3 Streptomyces coelicolor AL022268 (de:streptomyces coelicolor cosmid 4h2.) (nt:sc4h2.20, probable aminotransferase, len: 532;) 885967_c1_932 2454 19025 6i2 203 102 −2 Homo sapiens O00268 (sr:,human) (de:(tafii135) (tafii-130) 15752291_c1_934 2455 19026 1407 468 109 −6 Enterobacter cloacae CONTIG267 GTC ORF with score 109 to: (ai:7000764930) (or: Pseudomonas aeruginosa) 10558511_c1_938 2456 19027 480 159 258 −22 Shewanella putrefaciens AF044582 (de:shewanella putrefaciens nrfg homolog gene, partial cds; andmono-heme c-type cytochrome scya (scya), cytochrome c maturation- protein a (ccma), cytochrome c maturation protein b (ccmb), cytochrome c maturation protein c (ccmc), cytoc . . . 24025326_c1_939 2457 19028 609 202 932 −93 Pseudomonas aeruginosa P00106 (de:cytochrome c4) 35828836_c1_943 2458 19029 642 213 113 −4 herpes simplex virus type 2 Z86099 (de:herpes simplex virus type HSV-2 2 (strain hg52), complete genome.) 30642933_c1_945 2459 19030 789 262 168 −10 Plasmodium knowlesi P04922 (sr:nuri,) (de:circumsporozoite protein precursor (cs)) 1370416_c1_949 2460 19031 813 270 132 −5 Herpes simplex virus (type 6/ AF015297 (de:human herpesvirus 6 strain Uganda-1102) (strain uganda-1102) ie2hom mrna, complete cds.) (nt: similar to the immediate- early 2 protein of human) 36364066_c1_958 2461 19032 1446 481 635 −62 Escherichia coli P21345 (de:protein)) 35743952_c1_959 2462 19033 1230 409 376 −35 Cyanobacterium synechocystis S74647 (sr:pcc 6803, , pcc 6803) (sr: pcc 6803, ) 1445152_c1_963 2463 19034 1467 488 268 −23 Klebsiella pneumoniae Contig557A GTC ORF with score 268 to: (ai:7000764959) (or: Pseudomonas aeruginosa) 16831563_c1_970 2464 19035 471 156 468 −45 Klebsiella pneumoniae Contig490A GTC ORF with score 614 to: (ai:7000826942) (or: Enterobacter cloacae) 15094580_c1_975 2465 19036 762 253 174 −11 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22132306_c1_977 2466 19037 1095 364 305 −27 Klebsiella pneumoniae Contig544A GTC ORF with score 422 to: (ai:7000776439) (or: Pseudomonas aeruginosa) 16523968_c1_983 2467 19038 729 242 135 −6 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 23711443_c1_998 2468 19039 459 152 133 −8 Caenorhabditis elegans Z81138 (de:caenorhabditis elegans cosmid w05b2, complete sequence.) (nt:protein predicted using genefinder; preliminary) 22897512_c1_1000 2469 19040 255 84 22445430_c1_1001 2470 19041 1017 338 1446 −148 Pseudomonas aeruginosa AF009955 (fn:putative oxidoreductase, converting) (de:pseudomonas aeruginosa oxidoreductase rmd (rmd) gene, complete cds.) 36368882_c1_1008 2471 19042 1272 423 2144 −222 Pseudomonas aeruginosa U63723 (de:pseudomonas aeruginosa atp-binding protein (wzt) gene, completecds.) (nt:atp- binding protein component of an abc transport) 10833330_c1_1013 2472 19043 1182 393 1951 −201 Pseudomonas aeruginosa AF010182 (fn:transfers d-rhamnose in an alpha1-3 linkage) (de: pseudomonas aeruginosa glycosyltransferase wbpy (wbpy) gene,partial cds.) (nt: one of three glycosyl- transferases that function to) 2792702_c1_1014 2473 19044 1146 381 1949 −201 Pseudomonas aeruginosa AF010183 (fn:transfers d-rhamnose in an alpha1-3 linkage) (de: pseudomonas aeruginosa glycosyltransferase wbpz (wbpz) gene,complete cds.) (nt:one of three transferase that function to assemble) 16486662_c1_1016 2474 19045 1551 516 164 −11 Saccharomyces cerevisiae X68577 (sr:baker's yeast) (de: s. cerevisiae 11.4kb segment of chromosome ii.) 26737836_c1_1017 2475 19046 1773 590 417 −39 Enterobacter cloacae CONTIG444 GTC ORF with score 558 to: (ai:7501778866) (or: Klebsiella pneumoniae) 2786681_c1_1018 2476 19047 882 293 513 −49 Klebsiella pneumoniae Contig534A GTC ORF with score 1491 to: (ai:7000828858) (or: Enterobacter cloacae) 4305193_c1_1024 2477 19048 2211 736 36428808_c1_1026 2478 19049 573 190 94 −2 Caenorhabditis elegans AF000198 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 4774158_c1_1031 2479 19050 1521 506 388 −36 Klebsiella pneumoniae Contig460A GTC ORF with score 572 to: (ai:7000817687) (or: Enterobacter cloacae) 35570838_c1_1033 2480 19051 885 294 143 −7 southern root-knot nematode S34665 (cl:unassigned collagens) 40675_c1_1036 2481 19052 1953 650 545 −52 Aquifex aeolicus A70432 13141631_c1_1041 2482 19053 1179 392 100 −5 Klebsiella pneumoniae Contig242A GTC ORF with score 100 to: (ai:7000765037) (or: Pseudomonas aeruginosa) 32156682_c1_1045 2483 19054 1278 425 144 −6 Homo sapiens O00268 (sr:,human) (de:(tafii135) (tafii-130) 12351676_c1_1046 2484 19055 1275 424 25986318_c1_1051 2485 19056 546 181 153 −10 Achromobacter A61183 georgiopolitanum 32557031_c1_1055 2486 19057 648 215 812 −81 Pseudomonas aeruginosa P72157 (ec:4.1.1.21) (de:(ec 4.1.1.21) (air carboxylase) (airc)) 16986688_c1_1056 2487 19058 1101 366 1830 −189 Pseudomonas aeruginosa P72158 (ec:4.1.1.21) (de:(air carboxylase) (airc)) 5980443_c1_1057 2488 19059 258 85 i56 −11 Escherichia coli P76246 (de:hypothetical 8.7 kd protein in gapa-md intergenic region) 30333506_c1_1059 2489 19060 1245 414 7315778_c1_1063 2490 19061 1059 352 182 −13 Enterobacter cloacae CONTIG256 GTC ORF with score 729 to: (ai:7501728492) (or: Klebsiella pneumoniae) 33463306_c1_1064 2491 19062 405 134 131 −8 Orf virus D34768 15705141 _c1_1067 2492 19063 420 139 123 −8 longrin squid S56117 (sr:, longfin squid) 30161630_c1_1071 2493 19064 1635 544 92 −2 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 81/162.) (nt: rv1800, (rntv049.22), len: 655. member of m.) 10401007_c1_1076 2494 19065 672 223 16492717_c1_1078 2495 19066 378 125 108 −5 Boreogadus saida U432(X) (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spaccrs r or) 24851082_c2_1082 2496 19067 288 95 94 −4 Saccharomyces cerevisae S67570 (mp:41) 31849131_c2_1086 2497 19068 537 178 134 −7 Micrococcus luteus JQ0405 12398917_c2_1087 2498 19069 2079 692 35836631_c2_1089 2499 19070 927 308 407 −39 Rickettsia prowazekii AJ235269 Rickettsia prowazekii strain Madrid E, complete genome. 32549018_c2_1091 2500 19071 2280 759 94 −1 Arabidopsis thaliana AC002534 (sr:thale cress) (de: arabidopsis thaliana bac t32n15 from chromsome v, completesequence.) (nt:similar to maize nucleolar histone deacetylase) 4963285_c2_1097 2501 19072 261 86 103 −5 Pseudomonas aeruginosa U97065 (de:pseudomonas aeruginosa exou operon, complete sequence.) (nt:similar to hypothetical proteins from several) 26375331_c2_1098 2502 19073 951 316 915 −92 Xanthomonas campestris P25438 (de:insertion element is476 hypothetical 39.2 kd protein) 10942791_c2_1 102 2503 19074 582 193 6i2 −60 Klebsiella pneumoniae Contig558A GTC ORF with score 612 to: (ai:7000765098) (or: Pseudomonas aeruginosa) 32525656_c2_1111 2504 19075 432 143 156 −12 Enterobacter cloacae CONTIG146 GTC ORF with score 156 to: (ai:7000765107) (or: Pseudomonas aeruginosa) 15741555_c2_1117 2505 19076 1512 503 1903 −196 Pseudomonas putida P25755 (de:possible thiophene and furan oxidation protein thdf) 16880465_c2_1118 2506 19077 711 236 15136682_c2_1125 2507 19078 495 164 447 −42 Pseudomonas putida P25760 (de:atp synthase protein i) 31308575_c2_1126 2508 19079 468 155 110 −7 Klebsiella pneumoniae Contig199A GTC ORF with score 110 to: (ai:7000765122) (or: Pseudomonas aeruginosa) 30736031_c2_1136 2509 19080 876 291 1034 −104 Escherichia coli P00837 (ec:3.6.1.34) (de:atp synthase gamma chain,) 21542063_c2_1137 2510 19081 1407 468 2028 −210 Haemophilus influenzae P43715 (ec:3.6.1.34) (de:atp synthase beta chain,) 5213192_c2_1140 2511 19082 657 218 159 −12 Aquifex acolicus H70450 22520788_c2_1147 2512 19083 894 297 139 −6 Homo sapiens X15332 (sr:human) (de:human col3a1 mrna for pro alpha-1 (iii) collagen.) 12157253_c2_1151 2513 19084 1215 404 129 −5 Rattus norvegicus Q63003 (sr:,rat) (de:5e5 antigen) 2930418_c2_1155 2514 19085 2388 795 114 −3 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 51510_c2_1170 2515 19086 1653 550 1088 −110 Pseudomonas fluorescens P31521 (de:47 kd protein (p47k)) (biotype D) 33687633_c2_1172 2516 19087 1047 348 107 −2 Chinese oak silkmoth AF083334 (sr:chinese oak silkmoth) (de: antheraea pernyi fibroin gene, complete cds.) 26381925_c2_1174 2517 19088 1083 360 1794 −185 Pseudomonas aeruginosa Q51368 (de:tonb protein) 36066691 _c2_1175 2518 19089 1641 546 255 −19 Klebsiella pneumoniae Contig557A GTC ORF with score 106 to: (ai:392664) (or:Mus musculus) (sr:house mouse) (de:mus musculus glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 7163131_c2_1179 2519 19090 723 240 29767642_c2_1183 2520 19091 945 314 96 −1 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:cbna-1 nuclear protein) 13149140_c2_1185 2521 19092 1266 421 35672957_c2_1188 2522 19093 849 282 335 −30 Comamonas testosteroni U32622 (fn:catalyzes conversion of 4-sulfobenzyl alcohol) (de: comamonas testosteroni tsar (tsar), toluenesulfonatemethyl- monooxygcnase oxygenase component (tsam), toluene- sulfonatemethyl-mono- oxygenase reductase component (tsab), toluene- sulfonate . . . 32520937_c2_1189 2523 19094 609 202 353 −34 Helicobacter pylori GTC_H.pylori Hypothetical Conserved with J99 (GTC) no known function 34511305_c2_1192 2524 19095 684 227 373 −34 Rhodobacter capsulatus AF010496 (de:rhodobacter capsulatus strain sb1003, partial genome.) 32695752_c2_1193 2525 19096 351 116 95 −4 Achromobacter A61183 georgiopolitanum 2348538_c2_1195 2526 19097 531 176 34480162_c2_1198 2527 19098 1116 371 99 −2 Pinctada fucata D86074 (sr:pinctada fucata cdna to mrna) (de:pinctada fucata mrna for insoluble protein, complete cds.) 23698536_c2_1201 2528 19099 1359 452 1162 −118 Rhizobium meliloti P13632 (de:c4-dicarboxylate transport (megaplasmid pRME41B transcriptional regulatory SYM) protein dcdt) 6432893_c2_1203 2529 19100 1332 443 122 −4 Drosophila melanogaster P29617 (sr:,fruit fly) (de:protein prospero) 10041452_c2_1205 2530 19101 1416 471 182907_c2_1213 2531 19102 210 69 21500213_c2_1214 2532 19103 1200 399 208 −16 Kiebsiella pneumoniae Contig509A GTC ORF with score 208 to: (ai:7000765210) (or: Pseudomonas aeruginosa) 15652276_c2_1217 2533 19104 690 229 197 −16 Klebsiella pneumoniae Contig460A GTC ORF with score 197 to: (ai:7000765213) (or: Pseudomonas aeruginosa) 24304181_c2_1219 2534 19105 435 144 103 −3 Rattus norvegicus A54895 (sr:, norway rat) 3931327_c2_1221 2535 19106 2205 734 370 −30 Streptomyces coelicolor AL022268 (de:streptomyces coelicolor cosmid 4h2.) (nt:sc4h2.26, nrdj, ribonucleotide reductase, len: 967) 31538330_c2_1226 2536 19107 480 159 135 −8 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 473756_c2_1227 2537 19108 2814 937 2869 −299 Escherichia coli P00582 (ec:2.7.7.7) (de:dna poly- merase i, (pol i)) 36456316_c2_1235 2538 19109 2820 939 373 −33 Aquifex aeolicus H70302 33713592_c2_1236 2539 19110 711 236 42l −39 Escherichia coli P46851 (de:hypothetical 21.5 kd protein in asd-gntu intergenic region (o197)) 2583306_c2_1237 2540 19111 807 268 487 −46 Escherichia coli C64825 641665 l_c2_1241 2541 19112 1149 382 187 −14 Aeromonas hydrophila U56832 (de:aeromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 35720893_c2_1242 2542 19113 273 90 172 −13 Enterobacter cloacae CONTIG469 GTC ORF with score 172 to: (ai:7000765238) (or: Pseudomonas aeruginosa) 23954831_c2_1243 2543 19114 489 162 22111342_c2_1245 2544 19115 780 259 963 −97 Escherichia coli P21345 (de:protein)) 2597766_c2_1251 2545 19116 1359 452 1362 −139 Escherichia coli A23103 (cl:citrate utilization determinant) 16145693_c2_1260 2546 19117 1263 420 2i616456_c2_1262 2547 19118 1107 368 483 −46 Escherichia coli E64748 32683343_c2_1267 2548 19119 1482 493 131 −5 Molluscum contagiosum L10127 (sr:molluscum contagiosum virus subtype 1 virus type 1 dna) (de: molluscum contagiosum virus type 1 orf1 and orf2 dna.) (nt: orf17) 1305291_c2_1268 2549 19120 2343 780 24710067_c2_1276 2550 19121 1521 506 24851055_c2_1277 2551 19122 1641 546 25913467_c2_1282 2552 19123 486 161 91 −2 Rhesus Epstein Barr virus U93909 (sr:rhesus epstein barr virus) (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 15875161_c2_1284 2553 19124 1308 435 1348 −138 Pseudomonas aeruginosa U63722 (fn:integral membrane protein of an abc transport) (de: pseudomonas aeruginosa membrane-spanning domain msd (wzm) gene,complete cds.) 35798783_c2_1286 2554 19125 1866 621 104 −2 mice|C57BL/6xCBA/CaJ P17208 (sr:,mouse) (de:brain-specific hybrid homeobox/pou domain protein 3a (brn-3a) (brn-3.0)) 33838202_c2_1294 2555 19126 798 265 543 −53 Acinetobacter baumannii CONTIG183 GTC ORF with score 543 to: C (ai:7000765290) (or: Pseudomonas aeruginosa) 36062881_c2_1300 2556 19127 1773 590 213 −14 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 33678581_c2_1305 2557 19128 801 266 140 −6 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86. region ie-b) 35447018_c2_1308 2558 19129 567 188 116 −4 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 22397291_c2_1309 2559 19130 1449 482 745 −74 Klebsiella pneumoniae Contig544A GTC ORF with score 745 to: (ai:7000765305) (or: Pseudomonas aeruginosa) 14347910_c2_1311 2560 19131 228 75 146 −10 Enterobacter cloacae CONTIG322 GTC ORF with score 572 to: (ai:7501752341) (or: Klebsiella pneumoniae) 23989010_c2_1313 2561 19132 921 306 572 −55 Escherichia coli P46118 (de:hypolhetical 32.0 kd protein in pyka-zwf intergenic region) 13163165_c2_1316 2562 19133 954 317 857 −85 Aquifex aeolicus G70427 22870343_c2_1317 2563 19134 1839 612 1834 −189 Legionella pneumophila X99678 (de:l.pneumophila oada gene.) 97540_c2_1318 2564 19135 1398 465 1399 −143 Escherichia coli P22306 (de:tryptophan-specific transport protein (tryptophan permease)) 33879083_c2_1319 2565 19136 729 242 234 −20 Klebsiella pneumoniae Contig536A GTC ORF with score 358 to: (ai:7000843842) (or: Enterobacter cloacae) 30277283_c2_1320 2566 19137 1563 520 762 −75 Rhizobium leguminosarum AF076240 (de:rhizobium leguminosarum bv. viciae plasmid psyma mocc (mocc), putativenadh-inositol dehydrogenase moca (moca), putative rhizopineperiplasmic transport protein mocb precursor (mocb), putative- regulatory protein mocr (mocr). putative hydrocarb . . . 35644762_c2_1321 2567 19138 606 201 119 −5 Escherichia coli P33015 (de:hypothetical 38.1 kd protein in sbcb-hisl intergenic region) 29589590_c2_1322 2568 19139 555 184 219 −17 Salmonella choleraesuis Q06400 (de:hypothetical 44.2 kd serotype typhimurium protein in amya-flie intergenic region) 30589590_c2_1325 2569 19140 948 315 478 −45 Escherichia coli P39376 (de:hypothetical trans- criptional regulator in uxur- iada intergenic region) 36521057_c2_1326 2570 19141 441 146 204 −16 Klebsiella pneumoniae Contig543A GTC ORF with score 369 to: (ai:7000830111) (or: Enterobacter cloacae) 35182650_c2_1327 2571 19142 648 215 203 −17 Aspergillus fumigatus Contig8517 GTC ORF with score 203 to: (ai:7000765323) (or: Pseudomonas aeruginosa) 10041256_c2_1330 2572 19143 564 187 125 −6 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 4961555_c2_1332 2573 19144 624 207 14175416_c2_1338 2574 19145 3156 1051 30505016_c2_1342 2575 19146 1428 475 787 −78 Enterobacter cloacae CONTIG497 GTC ORF with score 1130 to: (ai:7501726099) (or: Klebsiella pneumoniae) 35267816_c3_1351 2576 19147 2088 695 1672 −172 Escherichia coli S47780 (cl:glycine--trna ligase beta chain) (ec:6.1.1.14) (mp: 80 min) 477012_c3_1356 2577 19148 573 190 282 −25 Cyanobacterium S76604 (cl:lmbk protein) (sr:pcc synechocystis 6803, , pcc 6803) (sr:pcc 6803, ) 9775767_c3_1365 2578 19149 291 96 365 −33 Burkholderia cepacia P24580 (sr:,pseudomonas cepacia) (de:insertion element is407 hypothetical 10.0 kd protein (orf4)) 11958580_c3_1366 2579 19150 195 64 145 −10 Pseudomonas aeruginosa U97065 (de:pseudomonas aeruginosa exou operon, complete sequence.) (nt:similar to hypothetical proteins from several) 10835458_c3_1369 2580 19151 342 113 154 −11 Enterobacter cloacae CONTIG500 GTC ORF with score 227 to: (ai:7501797512) (or: Klebsiella pneumoniae) 22792300_c3_1373 2581 19152 1197 398 307 −28 Klebsiella pneumoniae Contig558A GTC ORF with score 539 to: (ai:7000841433) (or: Enterobacter cloacae) 31844458_c3_1377 2582 19153 438 145 507 −48 Pseudomonas putida P25752 (ec:3.1.26.5) (de:ribonuclease p protein component, (protein c5) (rnase p)) 15711456_c3_1378 2583 19154 1980 659 1499 −216 Pseudomonas putida P25754 (de:60 kd inner-membrane protein) 11880168_c3_1384 2584 19155 252 83 103 −6 Enterobacter cloacae CONTIG258 GTC ORF with score 103 to: (ai:7000765380) (or: Pseudomonas aeruginosa) 12604693_c3_1386 2585 19156 648 215 142 −10 Enterobacter cloacae CONTIG258 GTC ORF with score 142 to: (ai:7000765382) (or: Pseudomonas aeruginosa) 35444531_c3_1387 2586 19157 939 312 832 −83 Pseudomonas putida P25757 (de:glucose inhibited division protein b) 36055468_c3_1388 2587 19158 666 221 913 −91 Pseudomonas putida P31856 (de:hypothetical 28.9 kd protein in gidb-unci intergenic region) 31354140_c3_1389 2588 19159 993 330 146 −7 Micrococcus luteus JQ0405 22461090_c3_1390 2589 19160 912 303 725 −72 Haemophilus influenzae P43719 (ec:3.6.1.34) (de:atp synthase a chain, (protein 6)) 12760167_c3_1392 2590 19161 753 250 394 −36 Escherichia coli P00831 (ec:3.6.1.34) (de:atp synthase delta chain,) 35817967_c3_1393 2591 19162 1557 518 2057 −213 Escherichia coli P00822 (ec:3.6.1.34) (de:atp synthase alpha chain,) 2469O953_c3_1403 2592 19163 774 257 490 −47 Escherichia coli P15082 (de:glucitol operon repressor) 26370462_c3_1404 2593 19164 1851 616 2001 −207 Escherichia coli X01631 (de:e. coli origin of replication oric and genes gid, unc, ecourf- 1 andglms.) (nt:glus protein) 32635786_c3_1406 2594 19165 840 279 121 −4 Bos primigenius taurus S20969 (pn:na+/ca2+,k+-exchanging protein:na+/ca2+,k+ anti- porter:na/ca,k-exchanger) (sr:, cattle) 2206890_c3_1410 2595 19166 1215 404 1445 −148 Pseudomonas putida P31049 (de:hypothetical 44.7 kd protein in lpd-3 5′region (orf3)) 6339531_c3_1412 2596 19167 2082 693 970 −97 Archacoglobus fulgidus B69308 14947176_c3_1422 2597 19168 552 183 127 −6 Gallus gallus domesticus M25984 (sr:gallus gallus dna) (de: chicken alpha-2 collagen gene type i gene, exon 52.) 16667936_c3_1423 2598 19169 837 278 140 −8 Klebsiella pneumoniae Contig553A GTC ORF with score 410 to: (ai:7000828295) (or: Enterobacter cloacae) 7206877_c3_1424 2599 19170 423 140 264 −23 Caulobacter crescentus AF034413 (de:caulobacter crescentus dksa (dksa) gene, complete cds.) (nt:dnak suppressor protein homolog) 679030_c3_1429 2600 19171 999 332 416 −39 Escherichia coli P33030 (de:hypothetical 36.1 kd protein in frub-spr integenic region) 33681877_c3_1431 2601 19172 450 149 159 −10 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 3214092_c3_1436 2602 19173 1146 381 169 −10 Sus scrofa P18175 (sr:,pig) (de:involucrin) 6822636_c3_1437 2603 19174 1233 410 2422193_c3_1439 2604 19175 303 100 151 −11 Pseudomonas aeruginosa AF053982 (de:pseudomonas aeruginosa putative molybdotcrin-guanine dinucleotidebiosynthesis protein a (moba) and cyto- chrome c precursor protein (snrl) genes, complete cds; and unknown genes.) 5911583_c3_1442 2605 19176 612 203 106 −5 Enterobacter cloacae CONTIG508 GTC ORF with score 106 to: (ai:7000765438) (or: Pseudomonas aeruginosa) 26025087_c3_1444 2606 19177 1428 475 446 −42 Aquifex aeolicus C70371 24687780_c3_1451 2607 19178 1734 577 114 −4 Orf virus D34768 24511265_c3_1453 2608 19179 948 315 329 −30 Enterobacter cloacae CONTIG388 GTC ORF with score 330 to: (ai:7501734519) (or: Klebsiella pneumoniae) 32704566_c3_1457 2609 19180 1854 617 480 −46 Rhizobium leguminosarum P10047 (ec:2.7.3.—) (de:c4- dicarboxylate transport sensor protein dctb,) 30556381_c3_1471 2610 19181 1041 346 232 −20 Klebsiella pneumoniae Contig357A GTC ORF with score 397 to: (ai:7000813860) (or: Enterobacter cloacae) 24741682_c3_1472 2611 19182 1221 406 243 −20 Klebsiella pneumoniae Contig520A GTC ORF with score 466 to: (ai:7000822272) (or: Enterobacter cloacae) 33650331_c3_1477 2612 19183 321 106 123 −8 Klebsiella pneumoniae Contig502A GTC ORF with score 123 to: (ai:7000765473) (or: Pseudomonas aeruginosa) 25469438_c3_1481 2613 19184 600 199 109 −3 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 14558158_c3_i485 2614 19185 543 180 159 −12 Drosophila virilis A60095 (cl:salivary glue protein) (mp: x16a) 4042212_c3_1486 2615 19186 732 243 32320136_c3_1496 2616 19187 420 139 96 −5 Oryza sativa D16340 (sr:oryza sativa (strain nippon- bare, sub_species japonica) dna, clon) (ec:2.6.1.1) (de:rice dna, full sequence of rflp marker.) 23697207_c3_1497 2617 19188 639 212 1094 −111 Pseudomonas aeruginosa P95460 (de:thiol:disulfide interchange protein dsba precursor) 1208525_c3_1498 2618 19189 885 294 10245917_c3_1505 2619 19190 600 199 247 −21 Enterobacter cloacae CONTIG504 GTC ORF with score 682 to: (ai:7501777172) (or: Klebsiella pneumoniae) 12929205_c3_1514 2620 19191 1506 501 33370830_c3_1515 2621 19192 414 137 124 −7 Orf virus D34768 24883557_c3_1519 2622 19193 612 203 209 −16 Escherichia coli P76594 (de:hypothetical 98.0 kd protein in ung-pssa intergenic region) 12366683_c3_1522 2623 19194 2250 749 363 −33 Enterobacter cloacae CQNTIG432 GTC ORF with score 363 to: (ai:7000765518) (or: Pseudomonas aeruginosa) 16019582_c3_1525 2624 19195 1221 406 289 −25 Escherichia coli D64748 10330417_c3_1528 2625 19196 1416 471 119 −4 Sus scrofa domestica S27953 (sr:, domestic pig) 16306708_c3_1530 2626 19197 474 157 106 −4 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 3220340_c3_1532 2627 19198 501 166 189 −15 Aspergillus fumigatus Contig9993 GTC ORF with score 189 to: (ai:7000765528) (or: Pseudomonas aeruginosa) 1462791_c3_1537 2628 19199 576 191 102 −2 Alphaherpesvirus pseudo- B40505 rabies virus PRV 5103165_c3_1547 2629 19200 552 183 111 −3 California red abalone AF023459 (sr:california red abalone) (de: haliotis rufcscens lustrin a mrna, complete cds.) (nt: extracellular matrix protein; modular structure) 15896876_c3_1550 2630 19201 969 322 1630 −167 Pseudomonas aeruginosa Q51366 (ec:4.2.1.47) (de:gdp-mannose 4,6-dehydratase, (gdp-d- mannose dehydratase)) 5103408_c3_1551 2631 19202 1443 480 2443 −254 Pseudomonas aeruginosa AF009956 (fn:putative bifunctional enzyme having both) (de: pseudomonas aeruginosa phosphomannose isomerase/ gdp-mannosepyrophos- phorylase wbpx (wbpx) gene, complete cds.) 13804165_c3_1553 2632 19203 2790 929 2422 −251 Pseudomonas aeruginosa AF010181 (fn:transfers d-rhamnose in an alpha1-2 linkage) (de: pseudomonas aeruginosa glycosyltransferase wbpx (wbpx) gene,complete cds.) (nt:one of three transferases which function to) 12001011_c3_1556 2633 19204 555 184 111 −7 Klebsiella pneumoniae Contig274A GTC ORF with score 111 to: (ai:7000765552) (or: Pseudomonas aeruginosa) 16486593_c3_1565 2634 19205 3066 1021 1039 −105 Cyanobacterium S74707 (cl:response regulator synechocystis homology) (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) 35292666_c3_1567 2635 19206 1248 415 25883561_c3_1568 2636 19207 1077 358 24879067_c3_1577 2637 19208 354 117 10647808_c3_1584 2638 19209 372 123 123 −7 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 9933408_c3_1585 2639 19210 516 171 96 −2 Fundulus heteroclitus Q90508 (sr:,killifish:mummichog) (de: phosvitin (pv); lipovitcllin 2 (lv2))) 4397580_c3_1588 2640 19211 720 239 131 −9 Enterobacter cloacae CONTIG438 GTC ORF with score 131 to: (ai:7000765584) (or: Pseudomonas aeruginosa) 25784408_c3_1591 2641 19212 1563 520 195 −14 Escherichia coli X02307 (de:e. coli aspa gene for aspartase (l-aspartate ammonia-lyase) (ec4.3.1.1).) (nt:urf 4) 14542583_c3_1593 2642 19213 750 249 190 −15 Aspergillus fumigatus Contig8125 GTC ORF with score 106 to: (ai:194929) (or:Homo sapiens) (sr:, man) 22072543_c3_1595 2643 19214 1278 425 103 −2 mice|C57BL/6xCBA/CaJ S04336 (cl:unassigned ribo- hybrid nucleoprotein repeat- containing proteins:ribo- nucleoprotein repeat homology) (sr:, house mouse) 2161667_c3_1600 2644 19215 687 228 111 −5 Aspergillus fumigatus Contig8669 GTC ORF with score 138 to: (ai:7000784485) (or: Pseudomonas aeruginosa) 31910205_c3_1602 2645 19216 291 96 108 −5 mice|C57BL/6xCBA/CaJ A55840 (cl:scavenger receptor hybrid cysteine-rich domain homology) (sr:, house mouse) 31823938_c3_1618 2646 19217 1374 457 1633 −168 Achromobacter AB001577 (sr:pseudomonas sp. georgiopolitanum cell_line:ncimb 10558 dna) (de:pseudomonas sp. dna for low specificity 1-threonine aidoiase,complete cds.) (nt: pyridoxal 5′-phosphate binding site: lysine 207.) 15836416_f1_1 2647 192i8 1251 416 459 −43 Sphingomonas AF079317 (de:sphingomonas aromaticivorans aromaticivorans plasmid pn11, complete plasmid- sequence.) (nt:putative transmembrane fusion component efflux nump) 11892266_f1_3 2648 19219 948 315 97 −3 Enterobacter cloacae CONTIG431 GTC ORF with score 145 to: (ai:7501742244) (or: Klebsiella pneumoniae) 31269817_f1_9 2649 19220 474 157 128 −7 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 16522930_f1_10 2650 19221 1401 466 173 −12 Klebsiella pneumoniae Contig305A GTC ORF with score 234 to: (ai:7000816743) (or: Enterobacter cloacae) 21775811_f1_12 2651 19222 1029 342 99 −2 Drosophila melanogaster P50887 (sr:,fruit fly) (de:60s ribosomal protein 122) 15907002_f1_14 2652 19223 531 176 137 −7 equine herpesvirus type 4 AF030027 (fn:very large tegument EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 3213205_f1_17 2653 19224 1452 483 139 −6 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4894427_f1_18 2654 19225 918 305 469 −44 Rhizobium sp. P55619 (sr:ngr234,) (de:syrm protein homolog 1 (symbiotic regulator)) 6770793_f1 _27 2655 19226 582 193 157 −10 Epstein-Barr virus P03181 (sr:b95-8,human herpesvirus 4) (de:hypothetical bhlf1 protein) 12708507_f1_28 2656 19227 1161 386 i2589442_f1_31 2657 19228 438 145 110 −6 mice|C57BL/6xCBA/CaJ A60830 (cl:cytoskeletal keratin) (sr:, hybrid house mouse) 16129017_f1_33 2658 19229 831 276 158 −8 equine herpesvirus type 1 D88733 (sr:equine herpesvirus 1 EVH-1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 35254566_f1_34 2659 19230 1476 491 129 −5 Burkholderia cepacia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 36523952_f1_35 2660 19231 1866 621 172 −9 Methanococcus jannaschii Q58516 (ec:6.3.5.4) (de:putative asparagine synthetase (glutamine-hydrolyzing),) 13072958_f1_39 2661 19232 1269 422 14884716_f1_40 2662 19233 771 256 508 −49 Escherichia coli P46852 (de:hypothetical 26.3 kd protein in gntr-ggt intergenic region (f231)) 12226007_f1 _41 2663 19234 1014 337 98 −5 Klebsiella pneumoniae Contig542A GTC ORF with score 174 to: (ai:7000781708) (or: Pseudomonas aeruginosa) 14947958_f1_43 2664 19235 2148 715 115 −4 mice|C57BL/6xCBA/CaJ U46463 (sr:house mouse) (de:mus hybrid musculus glutamine repeat protein-1 mrna, complete cds.) (nt:grp-1) 5208418_f1_46 2665 19236 996 331 141 −9 Enterobacter cloacae CONTIG466 GTC ORF with score 141 to: (ai:7000765660) (or: Pseudomonas aeruginosa) 292556_f1_47 2666 19237 810 269 234 −20 Klebsiella pneumoniae Contig380A GTC ORF with score 609 to: (ai:7000813950) (or: Enterobacter cloacae) 14651012_f1_48 2667 19238 1074 357 528 −51 Cyanobacterium synechocystis S77111 (sr:pcc6803, , pcc6803) (sr:pcc6803,) 12536703_f1_52 2668 19239 612 203 115 −4 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 29775826_f1_53 2669 19240 507 168 228 −19 Enterobacter cloacae CONTIG396 GTC ORF with score 467 to: (ai:7501736100) (or: Klebsiella pneumoniae) 15089705_f1_56 2670 19241 1599 532 187 −14 Klebsiella pneumoniae Contig560A GTC ORF with score 187 to: (ai:7000765670) (or: Pseudomonas aeruginosa) 35583330_f1_58 2671 19242 972 323 561 −54 Klebsiella pneumoniae Contig560A GTC ORF with score 561 to: (ai:7000765672) (or: Pseudomonas aeruginosa) 4392505_f1_59 2672 19243 603 200 15753955_f1_61 2673 19244 576 191 156 −10 black rat D88461 (sr:rattus rattus cdna to mrna) (de:rat mrna for n-wasp, complete cds.) 9870906_f1_62 2674 19245 420 139 99 −4 Schizosaccharomyces pombe Z95620 (sr:fission yeast) (de:s.pombe chromosome ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 7238576_f1_64 2675 19246 1440 479 104 −5 Acinetobacter baumannii CONTIG220 GTC ORF with score 104 to: C (ai:7000765678) (or: Pseudomonas aeruginosa) 6041701 _f1_68 2676 19247 1869 622 378 −35 Enterobacter cloacae CONTIG426 GTC ORF with score 122 to: (ai:163896) (or:Escherichia coli) 34510342_f1_79 2677 19248 540 179 168 −12 Orf virus D34768 12991682_f1_80 2678 19249 1020 339 222 −18 Klebsiella pneumoniae Contig508A GTC ORF with score 442 to: (ai:7000822876) (or: Enterobacter cloacae) 25527032_f1_82 2679 19250 303 100 139 −9 Rhodobacter sphaeroides Z46806 (de:rhodobacter sphaeroides yntc, napk, nape, napf, napd, nab and napegenes.) (nt:single transmembrane protein. similarity to) 13025667_f1_83 2680 19251 675 224 152 −8 equine herpesvirus type 4 AF030027 (fn:very large tegument EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 36114502_f1_84 2681 19252 2499 832 1177042_f1_85 2682 19253 687 228 831 −83 Paracoccus denitrificans Q56352 (sr:,subspthiosphaera pantotropha) (de:cytochrome c-type protein napc) 31375162_f1_89 2683 19254 1101 366 99 −3 Aspergillus fumigatus Contig3470 GTC ORF with score 121 to: (ai:7000812615) (or: Pseudomonas aeruginosa) 2464830_f1_94 2684 19255 816 271 340 −31 Caenorhabditis elegans U23517 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid d1022.) 10207207_f1_96 2685 19256 489 162 138 −9 Pseudomonas aeruginosa S29309 33786257_f _100 2686 19257 2715 904 1468 −150 Bradyrhizobium japonicum AF047687 (fn:cyclic beta-(1-3)-glucan synthase) (de:bradyrhizobium japonicum beta-(1-3)- glucosyl transferase (ndvb) gene complete cds.) (nt: processive glycosyl transferase.) 34508268_f1_101 2687 19258 2070 689 483 −46 Escherichia coli P36999 (ec:2.1.1.51) (de:methyl- transferase)) 23698813_f1_105 2688 19259 1548 5I5 169 −10 Klebsiella pneumoniae Contig560A GTC ORF with score 189 to: (ai:7000777501) (or: Pseudomonas aeruginosa) 13025705_f1_107 2689 19260 606 201 132 −9 Klebsiella pneumoniae Contig560A GTC ORF with score 132 to: (ai:7000765721) (or: Pseudomonas aeruginosa) 34100807_f1_110 2690 19261 417 138 151 −9 Saccharomyces cerevisiae P47179 (sr:,baker's yeast) (de: precursor) 13772692_f1_112 2691 19262 543 180 106 −3 Volvox carteri S22697 16507631 _f1_114 2692 19263 984 327 134 −6 Homo sapiens S10889 (cl:proline-rich protein) (sr:, man) 2189140_(‘3)f1_119 2693 19264 210 69 21875790_f1_122 2694 19265 399 132 25894431_f1_123 2695 19266 807 268 9847712_f1_124 2696 19267 918 305 106 −5 longfin squid S56117 (sr:, longfin squid) 21664756_f1_125 2697 19268 426 141 158 −10 Homo sapiens X65120 (fn:structural short chain collagen of cartilage) (sr: human) (de:h.sapiens co110al gene for alpha 1 (x) collagen.) 13177077_f1_126 2698 19269 783 260 114 −4 Araneus diadematus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, partial cds.) 15713506_f1_127 2699 19270 1629 542 325 −27 Schizosaccharomyces pombe Q10087 (sr:,fission yeast) (de: hypothetical amino-acid perinease c11d3.08c) 35338576_f1_134 2700 19271 855 284 98 −2 Pseudomonas putida X80272 (de:p.putida pprb gene.) 31760157_f1_136 2701 19272 864 287 528 −51 Salmonella choleraesuis U69493 (fn:probable repressor protein of gntr serotype typhimurium family) choleraesuis (de:salmonella typhimurium thij and orf1 genes, partial cds, and phnx,phnw, phnr, phns, phnt, phnu and phnv genes, complete cds.) 35828956_f1_137 2702 19273 1035 344 332 −30 Escherichia coli P36771 (de:probable transcriptional regulator lrha) 17057292_f1_142 2703 19274 1206 401 700 −69 Arabidopsis thaliana AL022603 (sr:thale cress) (de: arabidopsis thaliana dna chromosome 4, bac clone f18c5 (essaiiproject).) (nt: similarity to pig3 homo sapiens. pat:g2754812.) 26255168_f1_143 2704 19275 1785 594 815 −81 Escherichia coli P31658 (de:31.1 kd protein in dem- seru intergenic region) 2425705_f1_144 2705 19276 480 159 158 −11 Bacillus subtilis/Bacillus P40761 (de:hypothetical 15.7 kd globigii protein in pbpd-coma intergenic region (orf2)) 16097041_f1_145 2706 19277 417 138 15628887_f1_147 2707 19278 1488 495 601 −58 Escherichia coli P02982 (de:tetracycline resistance protein, class a (transposon tn1721)) 30605057_f1_148 2708 19279 405 134 109 −6 Aspergillus fumigatus Contig10292 GTC ORF with score 229 to: (ai:59485) (or:Saccharomyces cerevisiae) (sr:baker's yeast) (de:s.cerevisiae chromosome ix cosmid 9168.) (nt:ma15, stal, : 1367, cai: 0.3, amyh yeast D08640) 16875655_f1_155 2709 19280 396 131 96 −5 Klebsiella pneumoniae Contig485A GTC ORF with score 96 to: (ai:7000765769) (or: Pseudomonas aeruginosa) 34551041_f1_157 2710 19281 1866 621 228 −18 Klebsiella pneumoniae Contig443A GTC ORF with score 228 to: (ai:7000765771) (or: Pseudomonas aeruginosa) 16914536_f1_160 271 I T9282 1983 660 661 −65 Escherichia coli P46139 (de:hypothetical 46.0 kd protein in arof-rpls intergenic region) 3378387_f1_163 2712 19283 429 142 12929205_f1_167 2713 19284 459 152 105 −4 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15097681_f1_168 2714 19285 345 114 108 −5 equine herpesvirus type 1 P28968 (sr:ab4p,ehv-1) (de:glyco- EVH-1 protein x precursor) 13019442_f1_171 2715 19286 417 138 32317833_f1_173 2716 19287 2133 710 228 −18 Aspergillus fumigatus Contig9884 GTC ORF with score 228 to: (ai:7000765787) (or: Pseudomonas aeruginosa) 30605281_f1_182 2717 19288 447 148 164 −12 Klebsiella pneumoniae Contig511A GTC ORF with score 187 to: (ai:7000777179) (or: Pseudomonas aeruginosa) 12972581_f1_184 2718 19289 1206 401 145 −7 Caenorhahditis elegans Z70756 (de:caenorhabditis elegans cosmid t06e4, complete sequence.) (nt:predicted using genefinder; similar to collagen;) 16285840_f1_185 2719 19290 2235 744 355 −31 Aquifex acolicus H70302 10425641_f1_186 2720 19291 1728 575 610 −60 Enterobacter cloacae CONTIG458 GTC ORF with score 610 to: (ai:7000765800) (or: Pseudomonas aeruginosa) 16500716_f1_188 2721 19292 585 194 117 −4 Saccharomyces cerevisiae P32323 (sr:,baker's yeast) (de:a- agglutinin attachment subunit precursor) 31699041_f1_195 2722 19293 495 164 94 −5 Klebsiella pneumoniae Contig531A GTC ORF with score 94 to: (ai:7000765809) (or: Pseudomonas aeruginosa) 33863331_f1_198 2723 19294 1575 524 9864592_f1_199 2724 19295 597 198 115 −5 Bordetella parapertussis ZS4268 (fn:transposition) (de: b.parapertussis tnpa gene (insertion sequence is1002).) (nt:incomplete coding region (scc note under) 10244831_f1_206 2725 19296 372 123 106 −6 Aspergillus fumigatus Contig9493 GTC ORF with score 181 to: (ai:5500701468) (or:Equine herpesvirus 4) (fn:very large tegument protein) (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 24692783_f1_207 2726 19297 1287 428 146 −6 Herpes simplex virus AF015297 (de:human herpesvirus 6 (type 6/strain Uganda-1102) ie2hom mrna, complete cds.) (nt:similar to the immediate- early 2 protein of human) 33853782_f1_225 2727 19298 1437 478 3907962_f1_241 2728 19299 1512 503 189 −12 Enterobacter cloacae CONTIG474 GTC ORF with score 189 to: (ai:7000765855) (or: Pseudomonas aeruginosa) 35672026_f1_242 2729 19300 1284 427 140 −9 Enterobacter cloacae CONTIG474 GTC ORF with score 140 to: (ai:7000765856) (or: Pseudomonas aeruginosa) 35647566_f1_247 2730 19301 1197 398 1898 −196 Pseudomonas aeruginosa A36125 (cl:liv-binding protein) (mp: 64 min) 29933155_f1_249 2731 19302 1314 437 1178 −120 Pseudomonas aeruginosa P21628 (de:high-affinity branched- chain amino acid transport protein brae) 33723536_f1_255 2732 19303 579 192 112 −3 Fundulus heteroclitus Q90508 (sr:,killifish:mummichog) (de: phosvitin (pv); lipovitellin 2 (1v2))) 31928758_f1_261 2733 19304 483 160 93 −3 Enterobacter cloacae CONTIG365 GTC ORF with score 92 to: (ai:130638) (or:Plasmodium vivax) (cl:circumsporozoite protein:thrombospondin type 1 repeat homology) 36063250_f1_262 2734 19305 435 144 143 −10 Pseudomonas aeruginosa S29309 4558516_f1_265 2735 19306 696 231 10744840_f1_267 2736 19307 1386 461 250 −21 Enterobacter cloacae CONTIG455 GTC ORF with score 267 to: (ai:7501748555) (or: Klebsiella pneumoniae) 13021056_f1_272 2737 19308 657 218 106 −3 Homo sapiens U80742 (sr:human) (de:homo sapiens cagh4s mrna, complete cds.) (nt:glutamine rich) 12552281_f1_278 2738 19309 1848 615 159 −7 no gb taxonomy match U52064 (de:kaposi's sarcoma- associated herpes-like virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 15752336_f1_284 2739 19310 1284 427 171 −9 Saimiriine herpesvirus 2 Q01033 (sr:11,) (de:hypothetical gene 48 protein) 14183293_f1_287 2740 19311 987 328 195 −15 Klebsiella pneumoniae Contig443A GTC ORF with score 195 to: (ai:7000765901) (or: Pseudomonas aeruginosa) 23943837_f1_291 2741 19312 1227 408 33707306_f1_294 2742 19313 660 219 142 −8 Pseudomonas aeruginosa M32077 (sr:p.aeruginosa (strain pao, isolate pa02003) dna, from patien) (de:p.aeruginosa exopolysaccharide alginate regulatory protein (algpand algq) genes, complete cds.) (nt:alginate regulatory protein p; (put.); nutative) 970451_f1_298 2743 19314 1620 539 158 −8 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10038332_f1_302 2744 19315 843 280 149 −10 Klebsiella pneumoniae Contig541A GTC ORF with score 149 to: (ai:7000765916) (or: Pseudomonas aeruginosa) 13016638_f1_303 2745 19316 969 322 198 −16 Klebsiella pneumoniae Contig542A GTC ORF with score 198 to: (ai:7000765917) (or: Pseudomonas aeruginosa) 5213275_f1_305 2746 19317 234 77 123 −8 Aeromonas hydrophila U56832 (de:aeromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf1; similar to escherichia coli slyd gene product) 10286516_f1_307 2747 19318 2589 862 555 −52 Achromobacter P15558 (sr:se83,) (ec:3.5.1.11) (de: georgiopolitanum (cephalosporin acylase ii)) 14144376_f1_311 2748 19319 399 132 100 −4 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 2753783_f1_312 2749 19320 549 183 25801016_f2_313 2750 19321 231 76 107 −5 Burkholderia cepacia U38944 (sr:burkholderia cepacia strain=pc138) (de: burkholderia cepacia outer membrane lipoprotein (opcm) gene,partial cds.) (nt:outer membrane lipoprotein) 30569580_f2_317 2751 19322 1554 517 652 −64 Pseudomonas aeruginosa AF047693 (de:pseudomonas aeruginosa multidrug resistance efflux pump homologpmra (pmra) and multidrug resistance efflux pump homolog pmrb (pmrb) genes, complete cds.) (nt:14 tms efflux pump; similar to emrb of escherichia) 4823780_f2_320 2752 19323 888 295 118 −4 Plasmodium vivax M34697 (sr:p.vivax (strain thai; isolate nyu thai) sporozoite dna) (de: p.vivax circumsporozoite protein gene, complete cds.) (nt:circumsporozoite protein) 995336_f2_322 2753 19324 1656 551 136 −7 Klebsiella pneumoniae Contig305A GTC ORF with score 159 to: (ai:7000760621) (or: Pseudomonas aeruginosa) 16976068_f2_325 2754 19325 894 297 621 −60 Escherichia coli P76241 (de:hypothetical trans- criptional regulator in gapa-rnd intergenic region) 2354131_f2_333 2755 19326 654 217 95 −2 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 32605191_f2_334 2756 19327 426 141 103 −4 Drosophila melanogaster A37282 (cl:unassigned ribonucleo- protein repeat-containing proteins:ribonucleoprotein repeat homology) 14348528_f2_335 2757 19328 3291 1096 243 −16 Streptomyces chrysomallus AF047717 (fn:peptide synthetase) (de: streptomyces chrysomallus actinomycin synthetase ii (acmb) gene,complete cds.) (nt:acms ii) 10625330_f2_336 2758 19329 3027 1008 161 −9 white spruce LA7672 (sr:picea glauca mature somatic embryo cdna to mrna) (de:picca glauca embryo- abundant protein (emb34) mrna, complete cds.) (nt: embryo-abundant protein) 4582318_f2_337 2759 19330 1488 495 307 −23 Amycolatopsis mediterranei AF040570 (de:amycolatopsis mediterranei rifamycin biosynthetic gene cluster.) (nt:rifa) 16255031_f2_339 2760 19331 576 191 127 −6 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10446041_f2_342 2761 19332 2061 686 435 −40 Bacillus subtilis/Bacillus P54559 (de:hypothetical 44.7 kd globigii protein in glnq-ansr intergenic region) 12991342_f2_346 2762 19333 1155 384 173 −12 Cyanobacterium Q55705 (sr:pcc 6803,) (de:hypothetical synechocystis 23.8 kd protein slr0232) 5362837_f2_350 2763 19334 756 251 117 −5 Klebsiella pneumoniae Contig487A GTC ORF with score 141 to: (ai:1500696587) (or: Equine herpesvirus 1) (sr: equine herpesvirus 1 (strain: bk343, isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 14944591 _f2_351 2764 19335 501 166 282 −25 Klebsiella pneumoniae Contig426A GTC ORF with score 607 to: (ai:7000825532) (or: Enterobacter cloacae) 29978816_f2_363 2765 19336 411 136 114 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 22786293_f2_364 2766 19337 276 91 114 −6 Streptomyces coelicolor AL022374 (de:streptomyces coelicolor cosmid 5b8.) (nt:sc5b8.08, probable abc transporter, len: 744 aa;) 31853805_f2_365 2767 19338 495 164 108 −4 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 16141081_f2_366 2768 19339 2598 865 1132 −115 Pseudomonas aeruginosa P18275 (de:arginine/ornithine anti- porter) 12223780_f2_371 2769 19340 585 194 346 −31 Haemophilus influenzae P44119 (de:sprt protein homolog) 33460215_f2_373 2770 19341 570 189 102 −3 Pseudomonas aeruginosa P15276 (de:algr3)) 12995337_f2_375 2771 19342 492 163 109 −7 Candida albicans b3x16037.y GTC ORF with score 404 to: (ai:7501916224) (or: Aspergillus fumigatus) 5987882_f2_380 2772 19343 1122 373 500 −48 Escherichia coli P32064 (de:glycine cleavage system transcriptional activator) 31426458_f2_384 2773 19344 1185 394 240 −17 Gallus gallus domesticus A90458 (cl:collagen alpha 1(i) chain: fibrillar collagen carboxyl- terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 2525786_f2_389 2774 19345 852 283 141 −7 Klebsiella pneumoniae Contig508A GTC ORF with score 141 to: (ai:7000766003) (or: Pseudomonas aeruginosa) 32550956_f2_392 2775 19346 2544 847 3287 −9999 Rhodobacter sphaeroides AB016290 (sr:rhodobacter sphaeroides f. sp. denitrificans f. sp. denitrificans (str:i1106) dna) (de:rhodobacter sphaeroides f. sp. denitrificans napk, nape, napf, napd, napa, napb and napc genes, partial and complete cds.) 22135443_f2_393 2776 19347 516 171 100 −4 Aspergillus fumigatus Contig1021 GTC ORF with score 114 to: (ai:7000796469) (or: Pseudomonas aeruginosa) 10629587_f2_394 2777 19348 573 190 177 −13 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33485467_f2_395 2778 19349 1224 407 25682337_f2_396 2779 19350 1020 339 433 −41 Bacillus subtilis/Bacillus E69843 globigii 36585838_f2_397 2780 19351 429 142 116 −6 Caenorhabditis elegans Z81503 (de:caenorhabditis elegans cosmid f1417, complete sequence.) (nt:predicted using genefinder; similar to collagen;) 35838340_f2_405 2781 19352 594 197 115 −4 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22166076_f2_407 2782 19353 858 285 115 −4 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 12994761 _f2_410 2783 19354 456 151 115 −7 Homo sapiens I53641 (sr:, man) (mp:11p15.5- 11p15.5) 33713455_f2_417 2784 19355 873 290 915 −92 Escherichia coli P24176 (ec:3.5.1.18) (de:succinyl- diaminopimelate desuccinylase, (sdap)) 31894082_f2_422 2785 19356 240 79 130 −9 Enterobacter cloacae CONTIG392 GTC ORF with score 130 to: (ai:7000766036) (or: Pseudomonas aeruginosa) 35676903_f2_428 2786 19357 288 95 6275716_f2_433 2787 19358 1431 476 1072 −110 Chlamydia trachomatis AE001273 (de:chlamydia trachomatis section 82 of 87 of the complete genome.) 2585966_f2_436 2788 19359 627 208 7113163_f2_440 2789 19360 240 79 16879715_f2_449 2790 19361 2304 767 3318 −9999 Pseudomonas aeruginosa P11439 (ec:2.4.2.—) (de: (ec 2.4.2.—))) 22894457_f2_452 2791 19362 507 168 102 −3 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus hybrid musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 31454166_f2_453 2792 19363 993 330 131 −6 Orf virus D34768 4881532_f2_457 2793 19364 1590 529 443 −42 Salmonella choleraesuis P27669 (de:regulatory protein uhpc) serotype typhimurium 25909537_f2_458 2794 19365 771 256 102 −2 Alphaherpesvirus pseudo- B40505 rabies virus PRV 24096033_f2_461 2795 19366 870 289 304 −27 Escherichia coli P75713 (de:hypothetical 28.7 kd protein in gip-fdra intergenic region) 33808343_f2_462 2796 19367 483 160 97 −2 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib: pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 31925806_f2_464 2797 19368 654 217 133 −7 Caenorhahditis elegans Z70208 (de:caenorhabditis elegans cosmid f54b11, complete sequence.) (nt:predicted using genefinder, similar to collagen) 11744831_f2_476 2798 19369 984 327 204 −13 equine herpesvirus type 4 AF030027 (fn:very large tegument protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzv gene 22) 10407767_f2_480 2799 19370 1056 351 1039 −105 Bacillus subtilis/Bacillus P80874 (de:general stress protein 69 globigii (gsp69)) 31926705_f2_481 2800 19371 876 291 140 −7 Caenorhabditis elegans Z81124 (de:caenorhabditis elegans cosmid t21b4, complete sequence.) (nt:predicted using genefinder, similar to collagen) 25895375_f2_488 2801 19372 681 226 185 −14 Escherichia coli F65038 12525432_f2_492 2802 19373 510 169 300 −26 Escherichla coli P07021 (de:putative 15.3 kd lipo- proteinin arof-rpls intergenic region precursor) 31380030_f2_493 2803 19374 939 312 95 −2 Indian corn PQ0450 (cl:tryptophan synthase beta chain:tryptophan synthase beta chain homology) (sr:, maize) (ec:4.2.1.20) (mp: 10-41) 15037657_f2_495 2804 19375 2016 671 143 −5 herpes simplex virus type 2 Z86099 (de:herpes simplex virus type EHV-4 2 (strain hg52), complete genome.) 14312530_f2_496 2805 19376 453 150 211 −17 Acinetobacter baumannii CONTIG211 GTC ORF with score 211 to: C (ai:7000766110) (or: Pseudomonas aeruginosa) 33805290_f2_503 2806 19377 213 70 9879206_f2_506 2807 19378 549 182 92 −5 Klebsiella pneumoniae Contig410A GTC ORF with score 92 to: (ai:7000766120) (or: Pseudomonas aeruginosa) 25902253_f2_508 2808 19379 798 265 218 −18 Escherichia coli P32684 (de:hypothetical 32.5 kd protein in pepe-lysc intergenic region) 13020432_f2_509 2809 19380 435 144 142 −9 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 13145041_f2_510 2810 19381 1392 463 324 −29 Pseudomonas aeruginosa P32482 (de:chloramphenicol resistance protein) 2082276_f2_512 2811 19382 837 278 26050466_f2_514 28i2 19383 630 209 295 −26 Bacillus subtilis/Bacillus S14505 globigii 35781933_f2_518 2813 19384 2103 700 154 −10 Enterobacter cloacae CONTIG458 GTC ORF with score 154 to: (ai:7000766132) (or: Pseudomonas aeruginosa) 30566936_f2_527 2814 19385 1590 529 128 −5 Aeromonas hydrophila U56832 (de:aeromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 10666663_f2_529 2815 19386 1929 642 34239506_f2_530 2816 19387 1692 563 1452 −149 Pseudomonas aeruginosa AF003906 (de:pseudomonas aeruginosa a-type flagellin (flic) gene, partial cds.) 31270787_f2_532 2817 19388 465 154 103 −4 Pseudomonas aeruginosa P15276 (de:algr3)) 13933311_f2_541 2818 19389 1263 420 10427325_f2_544 2819 19390 300 99 112 −6 rhesus monkey I51920 (sr:, rhesus macaque) 16486683_f2_555 2820 19391 285 94 98 −4 Micrococcus luteus JQ0406 5330286_f2_557 2821 19392 1431 476 35336653_f2_558 2822 19393 1380 459 135 −7 Enterobacter cloacae CONTIG474 GTC ORF with score 135 to: (ai:7000766172) (or: Pseudomonas aeruginosa) 10636257_f2_559 2823 19394 1545 514 95 −1 Brassica napus S31415 (cl:phaseolus glycine-rich cell wall protein 1.8) (sr:, rape) 3184459i_f2_570 2824 19395 1482 493 915 −92 Pseudomonas aeruginosa P21628 (de:high-affinity branched- chain amino acid transport protein brae) 13095167_f2_571 2825 19396 1476 491 1157 −117 Pseudomonas aeruginosa P21630 (de:brag) 31517881_f2_572 2826 19397 645 214 170 −11 mice|C57BL/6xCBA/CaJ AF062655 (sr:house mouse) (de:mus musculus plenty-of-prolines- 101 mrna, complete cds.) (nt: binds to several sh3 domain containing proteins) 33471058_f2_573 2827 19398 429 142 120 −5 equine herpesvirus type 4 AF030027 (fn:very large tegument EHV-4 protein) (de:equine herpes- virus 4 strain ns80567, complete genome.) (nt: counterpart of hsv-1 gene u136 and vzy gene 22) 14142515_f2_575 2828 19399 525 174 146 −9 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 10808542_f2_577 2829 19400 843 280 120 −4 no gb taxonomy match P13290 (sr:type 2/hg52,) (de: glycoprotein g) 36432716_f2_579 2830 19401 1425 474 402 −37 Cyanobactcrium synechocystis S77469 (sr:pcc 6803, , pcc 6803) (sr: pcc 6803,) 1959708_f2_580 2831 19402 456 151 117 −6 Klebsiella pneumoniae Contig559A GTC ORF with score 250 to: (ai:1500692508) (or: Boreogadus saida) (de: borcogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4417581_f2_583 2832 19403 666 221 96 −2 Homo sapiens P41161 (sr:,human) (de:ets-related protein erm (ets translocation variant 5)) 5083141_f2_586 2833 19404 435 144 114 −6 Saccharomyces cerevisiae P32323 (sr:,baker's yeast) (de:a- agglutinin attachment subunit precursor) 16286533_f2_592 2834 19405 408 135 105 −5 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33651076_f2_595 2835 19406 996 331 101 −2 silkworm P05790 (sr:,silk moth) (de:fibroin heavy chain precursor (fib-h) (fragments)) 13719426_f2_597 2836 19407 645 214 131 −7 Enterobacter cloacae CONTIG505 GTC ORF with score 214 to: (ai:7501756990) (or: Klebsiella pneumoniae) 25828591_f2_598 2837 19408 714 237 245 −21 Klebsiella pneumoniae Contig479A GTC ORF with score 275 to: (ai:7000830930) (or: Enterobacter cloacae) 29976057_(—)f2_603 2838 19409 498 165 146 −10 Canadian hard winter wheat D87065 (sr:triticum aestivum dna, clone:th325) (de:triticum aestivum gene for histone h1, complete cds, clone:th325.) 12712678_f2_609 2839 19410 1671 556 35642026_f2_611 2840 19411 2823 940 15037943_f2_615 2841 19412 1065 354 323 −29 Haemophilus influenzae P44609 (de:hypothetical protein hi0277) 13072887_f2_617 2842 19413 654 217 636 −62 Haemophilus influenzae P45122 (de:hypothetical protein hi1240 precursor) 1265767_f2_622 2843 19414 684 227 673 −66 Escherichia coli P77526 (de:hypothetical 24.5 kd protein in pta-folx intergenic region) 15120788_f2_627 2844 19415 411 136 94 −3 Dictyostelium discoideum P14328 (sr:,slime mold) (de:spore coat protein sp96) 26297883_f2_630 2845 19416 819 272 171 −11 white sandalwood AF020261 (sr:white sandalwood) (de: santalum album proline rich protein mrna, complete cds.) 14925828_f3_631 2846 19417 1371 456 194 −12 Murine herpesvirus 68 U97553 (de:murine herpesvirus 68 strain wums, complete genome.) 35667208_f3_635 2847 19418 735 244 24105158_f3_637 2848 19419 438 145 110 −5 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 24852015_f3_638 2849 19420 444 147 153 −10 human herpesvirus type 6 U92288 (fn:helicase, helicase-primase HHV-6 complex) (de:human herpes- virus 6 serotype b putative major immcdiate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 11173817_f3_642 2850 19421 420 139 98 −4 Aspergillus fumigatus Contig6655 GTC ORF with score 100 to: (ai:362125) (or: Schizosaccharomyces pombe) (gn:dis 1+) (sr: schizosaccharomyces pombc dna) (de:yeast dis1+ gene for p93dis1, complete cds.) 33728756_f3_645 2851 19422 903 300 97 −2 Chlamydomonas reinhardtii S19114 strain UTEX 1061 33693753_f3_648 2852 19423 684 227 225 −19 Homo sapiens P16083 (sr:,human) (ec:1.6.99.2) (de: reductase)) 14978880_f3_651 2853 19424 921 306 113 −6 Murine herpesvirus 68 U97553 (de:murine herpesvirus 68 strain wums, complete genome.) 5157341 _f3_652 2854 19425 1191 396 323 −29 Escherichia coli P46885 (ec:3.2.1.—) (de:(murein hydrolase a) (mlt38)) 16291705_f3_656 2855 19426 1122 373 470 −43 Bacillus licheniformis U95370 (fn:antibiotic-biosynthesis) (de:bacillus licheniformis lichenysin biosynthesis ope: lichenysinsynthetase a (lica), lichenysin synthetase b (licb), lichenysinsynthetase c (licc), and thioesterase (licte) genes, complete cds ) (nt:licb) 26801041_f3_658 2856 19427 540 179 108 −3 Homo sapiens AC004493 (sr:human) (de:homo sapiens chromosome 16, cosmid clone 373c8 (lan1), complete- sequence.) 13142001_f3_659 2857 19428 1470 489 16924080_f3_660 2858 19429 1251 416 343 −31 Pyrococcus horikoshii AP000007 (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1485001-1738505 nt. position (717).) (nt:similar to pir: g64473 percent ident: 42.202 in) 12580030_f3_662 2859 19430 537 178 140 −8 equine herpesvirus type 4 AF030027 (fn:envelope glycoprotein EHV-4 (gp2)) (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:positional counterpart of hsv-1 gene us5; no) 16901082_f3_663 2860 19431 2616 871 173 −9 Burkholderia cepacia U41162 (sr:burkholderia cepacia strain=17616) (de: burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 29926930_f3_664 2861 19432 684 227 91 −4 Enterobacter cloacae CONTIG483 GTC ORF with score 190 to: (ai:7000771209) (or: Pseudomonas aeruginosa) 31892316_f3_666 2862 19433 837 278 105 −3 Caenorhabditis elegans Z36948 (de:caenorhabditis elegans cosmid d2089, complete sequence.) (nt:contains a valine and arginine rich domain,) 12191592_f3_668 2863 19434 1743 580 101 −2 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna, completecds.) 33724167_f3_683 2864 19435 2790 929 310 −26 Rattus norvegicus D86041 (sr:rattus norvegicus (strain:wistar) female kidney cdna to mrna) (de:rat mrna for n-g,n-g-dimethylarginine dimethylaminohydrolase, complete cds.) (nt:ddah) 30757831_f3_688 2865 19436 786 261 106 −4 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna, completecds.) 36227063_f3_689 2866 19437 618 205 600 −58 Escherichia coli P33365 (de:hypothetical 22.4 kd protein in pbpg-cdd intergenic region) 16926930_f3_691 2867 19438 1386 461 5339458_f3_702 2868 19439 1125 374 361 −33 Pseudomonas aeruginosa U73506 (de:pseudomonas aeruginosa ornithine utilization regulatory (orur)gene, complete cds.) (nt: regulatory locus for ornithine utilization) 22006917_f3_703 2869 19440 2856 951 145 −6 Achromobacter L81125 (sr:pseudomonas sp (strain georgiopolitanum imt37) dna) (de:pseudomonas sp. (strain imt37) mono- oxygenase subunit gene, completecds.) 33753133_f3_710 2870 19441 702 233 392 −36 Rhodobacter sphaeroides AB016290 (pn:iron-sulfur protein f. sp. dentirificans containing four (4fe-4s)) (sr: rhodobacter sphaeroides f. sp. denitriticans (str:i1106)dna) (de:rhodobacter sphacroides f. sp. denitriticans napk, napc, napf,napd, napa, napb and napc genes, partial and complet . . . 11210305_f3_716 2871 19442 597 198 398 −37 Ralstonia eutropha P39186 (de:cytochrome c-type protein napb precursor) 16302202_f3_725 2872 19443 1107 368 181 −11 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg- related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 25650833_f3_726 2873 19444 768 255 186 −14 Streptomyces coelicolor AL031107 (de:streptomyces coelicolor cosmid 5a7.) (nt:sc5a7.23, unknown, : 226 aa; similar to) 11771055_f3_727 2874 19445 861 286 423 −40 Klebsiella pneumoniae Contig417A GTC ORF with score 460 to: (ai:7000815727) (or: Enterobacter cloacae) 16926062_f3_728 2875 19446 2814 937 105 −1 Acanthamocba castellanii P19706 (sr:,amocba) (de:myosin heavy chain ib (myosin heavy chain iI)) 12973793_f3_732 2876 19447 579 192 94 −4 Klebsiella pneumoniae Contig492A GTC ORF with score 94 to: (ai:7000766346) (or: Pseudomonas aeruginosa) 32548941 _f3_733 2877 19448 639 212 36069806_f3_738 2878 19449 978 325 223 −18 Rhizobium sp. S28675 31895917_f3_740 2879 19450 2997 998 2474 −258 Chlamydia trachomatis AE001273 (de:chlamydia trachomatis section 82 of 87 of the complete genome.) 25970066_f3_742 2880 19451 1767 588 19411_f3_743 2881 19452 1269 422 14588332_f3_754 2882 19453 417 138 107 −5 Dictyostelium discoideum PJ4328 (sr:,slime mold) (de:spore coat protein sp96) 11191631_f3_755 2883 19454 438 145 153 −10 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 20572630_f3_756 2884 19455 1725 574 1457291_f3_757 2885 19456 1011 336 496 −47 Ralstonia eutropha 139568 (cl:lactaldehyde reductase: lactaldehyde reductase homology) (ec:1.1.1.61) 3260430_f3_763 2886 19457 993 330 310 −29 Mycobacterium tuberculosis AL123456 (de:mycobacterium tuberculosis h37rv complete genome; segment 25/162.) (nt:rv0505c, (mtcy20g9.32c), len: 373, probable) 31297706_f3_765 2887 19458 900 299 204 −15 Achromobacter A61183 georgiopolitanum 31758587_f3_768 2888 19459 1578 525 25836036_f3_769 2889 19460 1023 340 118 −5 Homo sapiens X06814 (sr:human) (de:human mrna for hul-70k small nuclear rnp protein (rnp12).) (nt:hul-70k protein (234 aa)) 24488956_f3_773 2890 19461 594 197 104 −4 Pseudomonas aeruginosa S29309 16198881_f3_776 2891 19462 1818 605 278 −23 Shigella flexneri P37782 (ec:2.—.—.—) (de:dtdp- rhamnosyl transferase rfbf,) 17089433_f3_777 2892 19463 873 290 127 −6 Klebsiella pneumoniae Contig501A GTC ORF with score 361 to: (ai:7000757282) (or: Pseudomonas aeruginosa) 12976082_f3_780 2893 19464 813 270 32511556_f3_783 2894 19465 489 162 5166458_f3_784 2895 19466 264 87 36120662_f3_788 2896 19467 1413 470 159 −8 Mycobacterium smegmatis AF034152 (de:mycobacterium smegmatis exochelin gene cluster, exit (exit) andfxbb (fxbb) genes, complete cds; and fxbc (fxbc) gene, partial cds.) (nt:abc transporter; this abc transporter probably) 24087702_f3_790 2897 19468 684 227 22146042_f3_791 2898 19469 447 148 127 −7 Murine herpesvirus 68 U97553 (de:murine herpesvirus 68 strain wums, complete genome.) 29297067_f3_793 2899 19470 2427 808 126 −4 Rattus norvegicus L07318 (fn:membrane protein of rat glomcrular epithelial) (sr: rattus norvegicus (strain sprague-dawley) kidney cdna to mrna) (de:rattus norvegicus minimal change nephritis trans- membraneglycoprotein mrna, partial cds.) 13944458_f3_794 2900 19471 564 187 113 −4 Caenorhabditis elegans AF000198 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 11039067_f3_798 2901 19472 501 166 239 −20 Klebsiella pneumoniae Contig482A GTC ORF with score 296 to: (ai:7000823980) (or: Enterobacter cloacae) 32553342_f3_799 2902 19473 660 219 344 −31 Enterobacter cloacae CONTIG461 GTC ORF with score 526 to: (ai:7501742639) (or: Klebsiella pneumoniae) 9879687_f3_804 2903 19474 873 290 109 −3 mice|C57BL/6xCBA/CaJ P49749 (sr:,mouse) (de:homeobox hybrid even-skipped homolog protein 2 (evx-2)) 26644830_f3_808 2904 19475 1125 374 105 −2 Gallus gallus domesticus S16501 (cl:unassigned collagens) (sr:, chicken) 32660083_f3_815 2905 19476 1617 538 436 −41 Enterobacter cloacae CONTIG458 GTC ORF with score 436 to: (ai:7000766429) (or: Pseudomonas aeruginosa) 32503800_f3_819 2906 19477 2142 713 169 −10 Acromonas hydrophila U56832 (de:acromonas hydrophila fk506 binding protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 32433415_f3_825 2907 19478 195 64 106 −6 Klebsiella pneumoniae Contig494A GTC ORF with score 134 to: (ai:7000793176) (or: Pseudomonas aeruginosa) 13769687_f3_827 2908 19479 543 180 92 −5 Klebsiella pneumoniae Contig512A GTC ORF with score 108 to: (ai:175201) (or: Chlamydomonas reinhardtii) (de:chlamydomonas reinhardtii vsp-3 mrna, complete cds.) (nt:amino acid feature: rod protein domain. aa 266 . . .) 13072076_f3_840 2909 19480 1383 460 22924150_f3_843 2910 19481 348 115 35566451_f3_861 2911 19482 489 162 94 −3 Enterococcus faecium CONTIG046 GTC ORF with score 199 to: C (ai:4500688524) (or: Enterococcus faecalis) 12994415_f3_866 2912 19483 1140 379 190 −15 Enterobacter cloacae CONTIG368 GTC ORF with score 619 to: (ai:7501750617) (or: Klebsiella pneumoniae) 35330341_f3_868 2913 19484 1422 473 10963338_f3_875 2914 19485 1233 410 333 −30 Enterobacter cloacae CONTIG474 GTC ORF with score 333 to: (ai:7000766489) (or: Pseudomonas aeruginosa) 17050328_f3_876 2915 19486 438 145 131 −9 Enterobacter cloacae CONTIG474 GTC ORF with score 131 to: (ai:7000766490) (or: Pseudomonas aeruginosa) 32660817_f3_883 2916 19487 1704 567 34098311_f3_884 2917 19488 1197 398 230 −16 Microbacterium X79027 (de:m.ammoniaphilum ammoniaphilum genes mamir and mamim.) 11995441_f3_886 2918 19489 936 311 1514 −155 Pseudomonas aeruginosa P21627 (de:high-affinity branched- chain amino acid transport protein brad) 29947715_f3_887 2919 19490 498 165 161 −12 Klebsiella pneumoniae Contig397A GTC ORF with score 315 to: (ai:7000836256) (or: Enterobacter cloacae) 2515778_f3_888 2920 19491 996 331 1300 −132 Pseudomonas aeruginosa P21629 (de:braf) 36073951_f3_891 2921 19492 2412 803 16821083_f3_892 2922 19493 525 174 120 −6 Caenorhabditis elegans U88170 (sr:caenorhabditis elegans strain=bristol n2) (de: caenorhabditis elegans cosmid c10g11.) (nt:coded for by c. elegans cdna yk65c4.5; coded for by) 11207340_f3_893 2923 19494 750 249 106 −3 Boreogadus saida U43200 (de:boreogadus saida anti- freeze glycopeptide afgp poly- protein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 2604543_f3_902 2924 19495 747 248 148 −9 Klebsiella pneumoniae Contig531A GTC ORF with score 250 to: (ai:7000842789) (or: Enterobacter cloacae) 6692013_f3_903 2925 19496 711 236 134 −6 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 26300833_f3_908 2926 19497 264 87 33697581_f3_909 2927 19498 1044 347 257 −21 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 472908_f3_912 2928 19499 1488 495 239 −20 Klebsiella Contig443A GTC ORF with score 552 to: (ai:7000832416) pneumoniae (or:Enterobacter cloacae) 36445332_f3_931 2929 19500 711 236 104 −4 Klebsiella Contig557A GTC ORF with score 104 to: (ai:7000766545) pneumoniae (or:Pseudomonas aeruginosa) 4948755_f3_932 2930 19501 528 175 148 −11 Acinetobacter CONTIG143 GTC ORF with score 148 to: (ai:7000766546) baumannii C (or:Pseudomonas aeruginosa) 22397878_f3_938 2931 19502 546 181 91 −2 Arabidopsis thaliana AC004005 (sr:thale cress) (de:arabidopsis thaliana chromosome ii bac f6e13 genomic sequence, complete sequence.) 31892592_f3_940 2932 19503 591 196 108 −4 Rattus norvegicus S24169 (sr:, norway rat) 31297916_f3_942 2933 19504 3876 1291 310 −26 Klebsiella Contig534A GTC ORF with score 414 to: (ai:7000827696) pneumoniae (or:Enterobacter cloacae) 12505443_c1_945 2934 19505 738 245 182 −12 Rattus norvegicus Z78279 (sr:norway rat) (de:r.norvegicus mrna for collagen alpha1 type i.) (nt:type i) 26769151_c1_949 2935 19506 2076 691 15101631_c1_951 2936 19507 687 228 12594592_c1_955 2937 19508 252 83 16511408_c1_958 2938 19509 849 282 192 −12 Mycobacterium AL021942 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 29/162.) (nt:rv0578c, (mtv039.16c), len: 1306. member of) 16916456_c1_969 2939 19510 567 188 134 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 13145282_c1_971 2940 19511 1455 484 1536 −157 Achromobacter A44832 georgiopolitanum 12281691_c1_973 2941 19512 1155 384 679 −67 Cyanobacterium P74211 (sr:pcc 6803,) (cc:1.4.3.5) (de:pyridoxamine 5′- synechocystis phosphate oxidase, (pnp/pmp oxidase)) 6034528_C1_974 2942 19513 723 240 149 −8 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 12366716_c1_976 2943 19514 1680 559 646 −63 Haemophilus D64108 influenzae 1994031_c1_981 2944 19515 2805 934 1766 −182 Rhizobium meliloti X93358 (de:r.meliloti pha(a,b,c,d,e,f,g) genes.) (megaplasmid pRME41B SYM) 31770452_c1_982 2945 19516 1362 453 119 −4 Human P16818 (sr:ad169,) (de:hypothetical protein ul61) cytomegalovirus 35273916_c1_983 2946 19517 690 229 223 −18 Rhodobacter AF010496 (ec:2.3.1.—) (de:rhodobacter capsulatus strain capsulatus sb1003, partial genome.) (nt:phae subunit) 6929757_c1_987 2947 19518 1113 370 1022 −103 Mycobacterium AL022121 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 155/162.) (nt:rv3684, (mtv025.032), len: 346. probable lyase,) 24345193_c1_994 2948 19519 891 296 97 −2 Streptomyces D85898 (sr:streptomyccs thermoviolaceus (strain:opc- thermoviolaccus 520) dna) (ec:3.1.1.6) (de:streptomyces thermoviolaceus dna for acetyl xylan esterase,complete cds.) 32038316_c1_995 2949 19520 939 312 164 −9 Plasmodium vivax U08977 (de:plasmodium vivax isolate ch-3 circumsporozoite protein gene,partial cds.) 6142951_c1_(—)999 2950 19521 492 163 100 −3 Human P16818 (sr:ad169,) (de:hypothetical protein ul61) cytomegalovirus 36069591_c1_1001 2951 19522 858 285 458 −44 Enterobacter cloacae CONTIG483 GTC ORF with score 533 to: (ai:7501740945) (or: Klebsiella pneumoniae) 10440707_c1_1003 2952 19523 1320 439 515 −50 Klebsiella Contig397A GTC ORF with score 801 to: (ai:7000836509) pneumoniae (or:Enterobacter cloacae) 26062892_c1_1006 2953 19524 897 298 342 −31 Vibrio U51896 (sr:vibrio parahaemolyticus strain=bb22) parahaemolyticus (de:vibrio parahaemolyticus lateral flagellar lafx locus: lfgn gene,partial cds, lfgm, lfga, lfgb, lfgc, and lfgd genes, complete cds,and lfge gene, partial cds.) (nt:potential lateral flagellar p . . . 4572167_c1_1007 2954 19525 717 238 310 −28 Salmonella P16321 (de:basal-body rod modification protein flgd) choleraesuis serotype typhimurium 9817908_c1_1008 2955 19526 1416 471 518 −50 Treponema Q56326 (de:flagellar hook protein flge) phagedenis 35673966_c1_1009 2956 19527 972 323 100 −5 common cuttlefish P80001 (sr:,common cuttlefish) (de:spermatid-specific protein t1 (contains: sperm protamine sp1)) 14588307_c1_1013 2957 19528 1533 510 135 −5 Homo sapiens AC004760 (sr:human) (de:homo sapiens chromosome 16, cosmid clone 316h7 (lanl), completesequence.) (nt:creb-binding protein) 11854667_c1_1014 2958 19529 909 302 210 −15 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 21688317_c1_1025 2959 19530 1098 365 383 −35 Streptomyces AL021409 (pn:3-oxoacyl-(acyl-carrier-protein) synthase) coelicolor (de:streptomyces coelicolor cosmid 3f7.) (nt:sc3f7.08, probable 3-oxoacyl-(acyl-carrier- protein)) 32673516_c1_1030 2960 19531 765 254 138 −9 Caulobacter AF062345 (fn:predicted to be involved in s-lps synthesis) crescentus (de:caulobacter crescentus sts1 (sts1), s-layer protein subunit (rsaa),abc transporter (rsad), rsae (rsae), lpsa (lpsa), lpsb (lpsb), andlpsc (lpsc) genes, complete cds.) (nt:predicted . . . 31333557_c1_1044 2961 19532 879 292 131 −6 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 14975463_c1_1049 2962 19533 399 132 609 −59 Pseudomonas L81176 (de:pseudomonas aeruginosa flagellin (flic), aeruginosa flag (flag), flagellar cap(flid), and flis (flis) genes, complete cds.) 32541567_c1_1053 2963 19534 399 132 555 −53 Pseudomonas L43064 (sr:pseudomonas aeruginosa (strain dg 1) dna) aeruginosa (de:pseudomonas aeruginosa flis, orf4, and regulatory protein (orf5)genes, complete cds, regulatory protein (orf6) and flagellum capprotein (flid) genes, partial cds.) (nt:orf4; putative) 33210937_c1_1057 2964 19535 1287 428 2012 −208 Pseudomonas L41213 (sr:pseudomonas aeruginosa (strain pak) dna) aeruginosa (de:pseudomonas aeruginosa (strain pak) putative fler kinase (fles) andtranscriptional activator (fler) genes, complete cds.) (nt:putative fler kinase) 33876406_c1_1058 2965 19536 1239 412 118 −3 Alphaherpesvirus P33479 (sr:kaplan,prv) (de:immediate-early protein pseudorabies virus ie180) PRV 31338188_c1_1062 2966 19537 1053 350 221 −18 Enterobacter cloacae CONTIG458 GTC ORF with score 221 to: (ai:7000766676) (or:Pseudomonas aeruginosa) 10004667_c1_1065 2967 19538 1443 480 1319 −134 Legionella U85783 (fn:secretion and assembly of flagella) pneumophila (de:legionella pneumophila flih (flih) gene, partial cds and nucleotidebinding protein flii (flii) gene, complete cds.) 34401043_c1_1066 2968 19539 510 169 126 −7 Rattus norvegicus S52418 (sr:, norway rat) 31379081_c1_1068 2969 19540 669 222 268 −22 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) dna) georgiopolitanum (de:pseudomonas sp. (strain imt37) monooxygenase subunit gene, completecds.) 30574083_c1_1076 2970 19541 510 169 90 −2 Anolis pulchellus U46857 (fn:precursor of yolk proteins, serum transport) (de:anolis pulchellus vitellogenin mrna, partial cds.) (nt:apvtg5; similar to chicken and xenopus phosvitin) 26457193_c1_1077 2971 19542 645 214 12713506_c1_1081 2972 19543 1800 599 880 −89 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 12238512_c1_1087 2973 19544 870 289 263 −23 Bacillus E69840 subtilis/Bacillus globigii 30525700_c1_1091 2974 19545 1821 606 108 −2 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) dna) georgiopolitanum (de:pseudomonas sp. (strain imt37) monooxygenase subunit gene, completecds.) 35788165_c1_1093 2975 19546 1734 577 1088 −110 Escherichia coli P15723 (ec:3.1.5.1) (de:deoxyguanosinetriphosphate triphosphohydrolase, (dgtpase)) 23855077_c1_1099 2976 19547 819 272 101 −5 Klebsiella Contig492A GTC ORF with score 113 to: (ai:7000776384) pneumoniae (or:Pseudomonas aeruginosa) 15760216_c1_1100 2977 19548 723 240 102 −3 Homo sapiens S37593 (sr:, man) 22081691_c1_1103 2978 19549 1071 356 143 −6 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 11720066_c1_1104 2979 19550 816 271 12187593_c1_1110 2980 19551 801 266 234 −19 Rhizobium Q03316 (sr:,biovar viciae) (de:rhir regulatory protein) leguminosarum 36019833_c1_1111 2981 19552 1107 368 219 −18 Klebsiella Contig559A GTC ORF with score 219 to: (ai:7000766725) pneumoniae (or:Pseudomonas aeruginosa) 26257083_c1_1114 2982 19553 1032 343 100 −3 Aspergillus Contig4441 GTC ORF with score 100 to: (ai:7000766728) fumigatus (or:Pseudomonas aeruginosa) 22159541_c1_1118 2983 19554 549 182 100 −3 Klebsiella Contig560A GTC ORF with score 163 to: (ai:7000693920) pneumoniae (or:Bacillus subtilis) (fn:unknown) (de:bacillus subtilis complete genome (section 16 of 21): from 2997771to 3213410.) 15761416_c1_1119 2984 19555 897 298 173 −13 Klebsiella Contig558A GTC ORF with score 186 to: (ai:7000773682) pneumoniae (or:Pseudomonas aeruginosa) 33867157_c1_1125 2985 19556 1137 378 223 −17 Achromobacter P52686 (sr:atcc 19151,) (de:sds degradation georgiopolitanum transcriptional activation protein) 31746033_c1_1128 2986 19557 1629 542 119 −4 Sus scrofa P18175 (sr:,pig) (de:involucrin) 34097562_c1_1138 2987 19558 288 95 457 −43 Pseudomonas Q06578 (de:immunity protein for pyocin s1) aeruginosa 16833452_c1_1140 2988 19559 273 90 30526958_c1_1149 2989 19560 963 320 95 −1 Saccharomyces P47033 (sr:,baker's yeast) (de:hypothetical 89.2 kd cerevisiae protein in scp160-smc3 intergenic region) 26353140_c1_1155 2990 19561 2523 840 488 −46 Escherichia coli P18392 (ec:2.7.3.—) (de:sensor protein rstb,) 34431877_c1_1160 2991 19562 510 169 184 −14 Klebsiella Contig545A GTC ORF with score 340 to: (ai:7000845528) pneumoniae (or:Enterobacter cloacae) 13132158_c1_1161 2992 19563 654 217 171 −13 Acinetobacter CONTIG220 GTC ORF with score 255 to: (ai:7501786126) baumannii C (or:Klebsiella pneumoniae) 16209667_c1_1162 2993 19564 2673 890 113 −2 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 16902080_c1_1166 2994 19565 1335 444 35836631 _c1_1170 2995 19566 264 87 97 −4 Homo sapiens X15332 (sr:human) (de:human col3al mrna for pro alpha-1 (iii) collagen.) 22768781 _c1_1186 2996 19567 1092 363 135 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 16286456_c1_1189 2997 19568 753 250 600 −58 Salmonella P14146 (de:virulence transcriptional regulatory protein choleraesuis phop) serotype typhimurium 5198783_c1_1192 2998 19569 2460 819 108 −4 Enterobacter cloacae CONTIG489 GTC ORF with score 108 to: (ai:7000766806) (or:Pseudomonas aeruginosa) 16689693_c1_1194 2999 19570 852 283 95 −2 Enterobacter cloacae CONTIG488 GTC ORF with score 537 to: (ai:7000808294) (or:Pseudomonas aeruginosa) 4573442_c1_1198 3000 19571 1461 486 1628 −167 Salmonella P50334 (de:c4-dicarboxylate transport protein) choleraesuis serotype typhimurium 12973782_c1_1200 3001 19572 222 73 117 −7 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region) 33439807_c1_1201 3002 19573 327 108 3160001_c1_1202 3003 19574 2592 863 967 −99 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 121/162.) (nt:rv2724c, (mtcy154.04c), len: 386.fade20, probable) 12523261_c1_1204 3004 19575 825 274 121 −5 Plasmodium simium L05069 (sr:plasmodium simium dna) (de:plasmodium simium circumsporozoite protein type 2 (cs) gene,complete cds.) 25886438_c1_1207 3005 19576 1569 522 1012 −102 Escherichia coli P76055 (de:hypothetical 35.6 kd protein in dbpa-intr intergenic region) 7052257_c1_1212 3006 19577 1110 369 124 −4 no gb taxonomy P08393 (sr:type 1/17,) (de:ie110) (vmw110) (alpha-0 match protein)) 6307163_c1_1215 3007 19578 627 208 313 −28 Pseudomonas AF054868 (de:pseudomonas aeruginosa autoinducer aeruginosa synthetase (rhli) gene, partialcds; cyclohexadienyl dehydratase (phec), hypothetical 0299 protein(yigm), chloramphenicol-sensitive protein (rard), and hypotheticalprotein (yafl) genes, complete . . . 36586451 _c1_1219 3008 19579 657 218 143 −9 Enterdcoccus CONTIG108 GTC ORF with score 1137 to: faecalis (ai :7000759121) (or:Pseudomonas aeruginosa) 36582291_c1_1220 3009 19580 810 269 847 −84 Escherichia coli P21367 (de:hypothetical 23.1 kd protein in dmsc-pfla intergenic region) 12992716_cl _1225 3010 19581 2163 720 1293 −132 Myxococcus xanthus U37008 (sr:myxococcus xanthus strain=1s500) (de:myxococcus xanthus socd (socd500 allele) and kefc genes, completecds.) 31848966_c1_1227 3011 19582 987 328 93 −1 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 6489541_c1_1229 3012 19583 828 275 223 −19 Klebsiella Contig533A GTC ORF with score 733 to: (ai:7000836442) pneumoniae (or:Enterobacter cloacae) 6333566_c1_1235 3013 19584 1533 510 15750452_c1_1252 3014 19585 438 145 111 −7 Streptococcus CONTIG811 GTC ORF with score 650 to: (ai:7000802493) pneumoniae D (or:Pseudomonas aeruginosa) 7292626_c1_1254 3015 19586 483 160 162 −12 Klebsiella Contig556A GTC ORF with score 162 to: (ai:7000766868) pneumoniae (or:Pseudomonas aeruginosa) 22784591_c1_1256 3016 19587 1083 360 393 −36 Homo sapiens A32667 (sr:, man) (ec:1.6.99.2) (mp:6pter-6q12) 10199081_c1_1262 3017 19588 249 82 92 −4 Enterobacter cloacae CONTIG398 GTC ORF with score 373 to: (ai:7501763789) (or:Klebsiella pneumoniae) 29583155_c1_1263 3018 19589 360 119 205 −17 Klebsiella Contig500A GTC ORF with score 373 to: (ai:7000822950) pneumoniae (or:Enterobacter cloacae) 4112928_c1_1264 3019 19590 288 95 12167283_c1_1265 3020 19591 921 306 554 −53 Escherichia coli P76185 (de:hypothetical 33.0 kd protein in slya-sodc intergenic region) 16286062_c1_1269 3021 19592 822 273 362 −33 Escherichia coli P76241 (de:hypothetical transcriptional regulator in gapa-rnd intergenic region) 5291083_c1_1273 3022 19593 1323 440 219 −18 Klebsiella Contig560A GTC ORF with score 219 to: (ai:7000766887) pneumoniae (or:Pseudomonas aeruginosa) 494530_c2_1275 3023 19594 1833 610 902 −90 Escherichia coli P27850 (de:hypothetical 54.7 kd protein in udp-ubie intergenic region precursor) 651915_c2_1290 3024 19595 708 235 274 −24 Pseudomonas U19743 (fn:major outer membrane protein) fluorescens (de:pseudomonas fluorescens major outer- membrane protein f precursor(oprf) gene, partial cds.) (nt:sequence from pcr products) 31488331_c2_1295 3025 19596 807 268 123 −5 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 16296880_c2_1297 3026 19597 1140 379 150 −8 Burkholderia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob cepacia (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 12755068_c2_1298 3027 19598 768 255 124 −4 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 16988291_c2_1302 3028 19599 408 135 120 −8 Aspergillus Contig6746 GTC ORF with score 139 to: (ai:175201) fumigatus (or:Chlamydomonas reinhardtii) (de:chlamydomonas reinhardtii vsp-3 mrna, complete cds.) (nt:amino acid feature: rod protein domain, aa 266 . . .) 25447956_c2_1304 3029 19600 945 314 214 −17 Escherichia coli P37665 (de:precursor (o219)) 35235006_c2_1305 3030 19601 1473 490 481 −46 Escherichia coli P37047 (de:hypothetical 44.3 kd protein in htra-dapd intergenic region) 35254783_c2_1308 3031 19602 1014 337 168 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 20802193_c2_1309 3032 19603 450 149 113 −7 longfin squid S56117 (sr:, longfin squid) 13771031_c2_1313 3033 19604 237 78 98 −4 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32605131_c2_1315 3034 19605 1551 516 884 −88 Rhizobium meliloti X93358 (de:r.meliloti pha(a,b,c,d,e,f,g) genes.) (megaplasmid pRME41B SYM) 9852217_c2_1316 3035 19606 627 208 197 −16 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 29791705_c2_1319 3036 19607 753 250 100 −3 Enterococcus CONTIG588 GTC ORF with score 331 to: (ai:7000741201) faccalis (or:Enterococcus faecium) 32302157_c2_1322 3037 19608 516 171 292 −26 Escherichia coli P76243 (de:hypothetical 14.2 kd protein in gapa-rnd intergenic region) 31442193_c2_1323 3038 19609 1017 338 131 −5 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 16848466_c2_1324 3039 19610 1917 638 310 −24 Homo sapiens AF043254 (fn:molecular chaperone) (sr:human) (de:homo sapiens heat shock protein 75 (hsp75) mrna, partial cds.) (nt:similar to gallus gallus heat shock protein 90 beta) 24633465_c2_1325 3040 19611 2310 769 16533266_c2_1327 3041 19612 1284 427 619 −61 Klebsiella Contig397A GTC ORF with score 911 to: (ai:7000836411) pneumoniae (or:Enterobacter cloacac) 10438468_c2_1330 3042 19613 912 303 173 −10 Saimiriine Q01033 (sr:11,) (de:hypothetical gene 48 protein) herpesvirus 2 24485707_c2_1333 3043 19614 432 143 7167780_c2_1334 3044 19615 429 142 36442875_c2_1335 3045 19616 471 156 289 −25 Escherichia coli P75934 (de:flagellar basal-body rod protein flgb (putative proximal rod protein)) 30211557_c2_1337 3046 19617 402 133 119 −6 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 24100633_c2_1338 3047 19618 408 135 148 −9 Saccharomyces P47179 (sr:,baker's yeast) (de:precursor) cerevisiae 24491631_c2_1340 3048 19619 795 264 446 −42 Escherichia coli P75938 (de:flagellar basal-body rod protein flgf (putative proximal rod protein)) 17083556_c2_1343 3049 19620 1416 471 1584 −163 Pseudomonas putida Q52082 (de:flagellar p-ring protein precursor) 22133318_c2_1344 3050 19621 1500 499 16657931_c2_1345 3051 19622 417 138 94 −2 blue mussel AF015539 (sr:blue mussel) (de:mytilus edulis precollagen p (precol-p) mrna, complete cds.) 15052158_c2_1350 3052 19623 1320 439 308 −27 Salmonella P16326 (de:protein)) choleraesuis serotype typhimurium 29706961_c2_1351 3053 19624 1425 474 554 −53 Saccharopolyspora Y11199 (fn:involved in desosamine biosynthesis) erythraea (de:s.erythraea erythromycin gene cluster dna.) 22470336_c2_1352 3054 19625 261 86 25485955_c2_1354 3055 19626 804 267 321 −29 Gluconobacter P50199 (ec:1.1.1.69) (de:reductase)) oxydans 31297806_c2_1356 3056 19627 1590 529 279 −22 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromaticivorans pn11, complete plasmidsequence.) (nt:similar to a. calcoaceticus benzoate) 36531557_c2_1358 3057 19628 1158 385 24230143_c2_1362 3058 19629 822 273 379 −35 Escherichia coli P42216 (ec:2.7.7.38) (de:synthetase) (cmp-2-keto-3- deoxyoctulosonic acid synthetase) (cks)) 2995458_c2_1363 3059 19630 1116 371 21931590_c2_1364 3060 19631 1620 539 254 −22 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 1471162.) (nt:rv3469c, (mtcy13e12.22c), len: 336. mhpe: probable) 22770191_c2_1365 3061 19632 3621 1206 531 −56 Rhizobium sp. P55465 (sr:ngr234,) (de:hypothetical 102.8 kd protein y4gi) 29813336_c2_1374 3062 19633 429 142 660 −65 Pseudomonas L81176 (de:pseudomonas aeruginosa flagellin (flic), aeruginosa flag, (flag), flagellar cap(flid), and flis (flis) genes, complete cds.) 20729578_c2_1376 3063 19634 192 63 140 −10 Pseudomonas L81176 (de:pseudomonas aeruginosa flagellin (flic), aeruginosa flag (flag), flagellar cap(flid), and flis (flis) genes, complete cds.) (nt:orf 96) 31335816_c2_1378 3064 19635 1437 478 138 −6 Orf virus B34768 32683275_c2_1384 3065 19636 1461 486 2355 −244 Pseudomonas L41213 (fn:regulates adhesion to mucin; regulates) aeruginosa (sr:pseudomonas aeruginosa (strain pak) dna) (de:pseudomonas aeruginosa (strain pak) putative fler kinase (fles) andtranscriptional activator (flcr) genes, complete cds.) 24065776_c2_1386 3066 19637 387 128 527 −51 Pseudomonas Q51462 (de:flagellar hook-basal body complex protein aeruginosa flic) 35328551_c2_1387 3067 19638 876 291 92 −4 Enterobacter cloacae CONTIG472 GTC ORF with score 155 to: (ai:7000784293) (or:Pseudomonas aeruginosa) 35807626_c2_1388 3068 19639 732 243 102 −3 Klebsiella Contig559A GTC ORF with score 111 to: (ai:7500988895) pneumoniae (or:Caenorhabditis elegans) (de:caenorhabditis elegans cosmid c18h7.) (nt:similar to cuticular collagen; c18h7.3) 4427178_c2_1389 3069 19640 1026 341 1125 −114 Pseudomonas Q51464 (de:flagellar motor switch protein flig aeruginosa (fragment)) 24822168_c2_1393 3070 19641 447 148 204 −16 Escherichia coli P52613 (de:flagellar flij protein) 24862715_c2_1402 3071 19642 867 288 345 −31 Escherichia coli P76241 (de:hypothetical transcriptional regulator in gapa-rnd intergenic region) 49142_c2_1405 3072 19643 1182 393 757 −75 Escherichia coli P75804 (de:hypothetical 41.1 kd protein in moea-dacc intergenic region precursor) 10836708_c2_1409 3073 19644 477 158 90 −4 Enterobacter cloacac CONTIG467 GTC ORF with score 90 to: (ai:7000767023) (or:Pseudomonas aeruginosa) 31335041_c2_1411 3074 19645 2556 851 123 −3 Trypanosoma cruzi A44937 (cl:kinetoplast-associated protein) 12932342_c2_1417 3075 19646 609 202 100 −2 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain uganda-1102) (type 6/strain ie2hom mrna, complete cds.) (nt:similar to the Uganda-1102) immediate-early 2 protein of human) 36021881_c2_1421 3076 19647 558 185 290 −27 Chlamydia AE001273 (de:chlamydia trachomatis section 35 of 87 of trachomatis the complete genome.) 4566581_c2_1428 3077 19648 813 270 586 −58 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 50/162) (nt:rv1151c, (mtci65.18c), len: 237. similar to) 14728881_c2_1433 3078 19649 939 312 556 −54 Escherichia coli P75836 (de:hypothetical transcriptional regulator in dmsc-pfla intergenic region) 31511281_c2_1434 3079 19650 1236 411 128 −4 Molluscum L10127 (sr:molluscum contagiosum virus type 1 dna) contagiosum virus (de:molluscum contagiosum virus type 1 orf1 subtype 1 and orf2 dna.) (nt:orf17) 5159412_c2_1436 3080 19651 468 155 92 −5 Clostridium Contig226H GTC ORF with score 92 to: (ai:7000767050) acetobutylicum (or:Pseudomonas aeruginosa) 15027207_c2_1440 3081 19652 501 166 118 −5 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 36416542_c2_1447 3082 19653 1155 384 230 −19 Azospirillum AF083219 (de:azospirillum brasilense transcription brasilense activator (atrab) gene,partial cds.) (nt:atrab) 16208158_c2_1448 3083 19654 939 312 170 −11 Bacillus C69870 subtilis/Bacillus globigii 6520956_c2_1451 3084 19655 591 196 117 −7 Enterobacter cloacae CONTIG260 GTC ORF with score 147 to: (ai:7000806997) (or:Pseudomonas aeruginosa) 17050040_c2_1453 3085 19656 714 237 167 −13 Klebsiella Contig060A GTC ORF with score 167 to: (ai:7000767067) pneumoniae (or:Pseudomonas aeruginosa) 16485208_c2_1454 3086 19657 417 138 98 −5 Klebsiella Contig481A GTC ORF with score 98 to: (ai:7000767068) pneumoniae (or:Pseudomonas aeruginosa) 32599153_c2_1457 3087 19658 1107 368 237 −18 Klebsiella Contig507A GTC ORF with score 308 to: (ai:7000768344) pneumoniae (or:Pseudomonas aeruginosa) 24714667_c2_1458 3088 19659 447 148 106 −4 mice|C57BL/6xCBA/ B34457 (sr:, house mouse) CaJ hybrid 31895765_c2_1463 3089 19660 405 134 131 −7 Paracentrotus lividus A36226 (cl:collagen alpha 2(i) chain:fibrillar collagen carboxyl-terminal homology) (sr:, common urchin) 21891691_c2_1473 3090 19661 207 68 26O38518_c2_1479 3091 19662 3009 1002 109 −2 Plasmodium JC6164 gallinaceum 34272028_c2_1482 3092 19663 945 314 516 −49 Escherichia coli P03025 (de:transcriptional regulatory protein ompr) 4426590_c2_1484 3093 19664 351 116 239 −20 Pseudomonas P95459 (de:major cold shock protein cspa) aeruginosa 30339693_c2_1488 3094 19665 423 140 191 −15 Klebsiella Contig545A GTC ORF with score 255 to: (ai:7000754118) pneumoniae (or:Acinetobacter baumannii) 22916665_c2_1496 3095 19666 855 284 798 −79 Escherichia coli Q46927 (de:hypothetical 28.6 kd protein in gcva-mlta intergenic region) 29738413_c2_1501 3096 19667 684 227 35359665_c2_1504 3097 19668 2079 692 609 −58 Plexaura homomalla AF003692 (fn:converts arachidonic acid to an allene oxide) (de:plexaura homomalla 8r- lipoxygenase-allene oxide synthase fusionprotein mrna, complete cds.) (nt:peroxidase-lipoxygenase fusion protein; naturally) 22786633_c2_1512 3098 19669 561 186 133 −6 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 1354166_c2_1515 3099 19670 1542 513 152 −7 Nephila clavipes A36068 10426590_c2_1516 3100 19671 1575 524 226 −15 Micrococcus luteus JQ0405 31808416_c2_1517 3101 19672 3387 1128 1720 −177 Escherichia coli P38097 (de:hypothetical 123.9 kd protein in udk-alka intergenic region) 34078215_c2_1519 3102 19673 702 233 134 −6 Gallus gallus A90458 (cl:collagen alpha 1(i) chain:fibrillar collagen domesticus carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 21897183_c2_1521 3103 19674 1185 394 177 −11 Mycobacterium P71557 (de:hypothetical 30.9 kd protein cy10d7.21) tuberculosis 22907258_c2_1524 3104 19675 1233 410 556 −54 Mycobacterium Z95584 (dc.:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 50/162.) (nt:rv1143, (mtci65.10), len: 360. strong similarity) 17047268_c2_1525 3105 19676 924 307 282 −25 Klebsiella Contig523A GTC ORF with score 282 to: (ai:7000767139) pneumoniae (or:Pseudomonas aeruginosa) 13094407_c2_1529 3106 19677 726 241 128 −7 Escherichia coli P05100 (ec:3.2.2.20) (de:glycosylase i, constitutive) (tag i)) 25782941_c2_1533 3107 19678 1437 478 616 −60 Escherichia coli P71229 (de:hydrogenase-4 transcriptional activator) 14557961_c2_1534 3108 19679 786 261 300 −26 Archaeoglobus C69459 fulgidus 259428_c2_1537 3109 19680 597 198 329 −30 Escherichia coli P76190 (de:hypothetical 29.9 kd protein in 1hr-sodb intergenic region precursor) 30604215_c2_1542 3110 19681 426 141 138 −9 white sandalwood AF020261 (sr:white sandalwood) (de:santalum album proline rich protein mrna, complete cds.) 9899030_c2_1543 3111 19682 2136 711 175 −11 Mycobacterium Z97050 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 10/162.) (nt:rv0181c, (mtci28.21c), unknown, len: 244 aa:) 15867643_c2_1544 3112 19683 633 210 2600775_c2_1546 3113 19684 1632 543 1422 −145 Mycobacterium Z83864 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 159/162.) (nt:rv3854c, (mtcy01a6.14), len: 489. possible) 12210067_c2_1547 3114 19685 420 139 130 −7 Micrococcus luteus JQ0406 11922082_c2_1564 3115 19686 792 263 120 −4 Beta vulgaris S51939 (sr:, beet) (ec:3.2.1.14) 31725817_c2_1571 3116 19687 1365 454 13100836_c2_1574 3117 19688 1305 434 16931705_c2_1577 3118 19689 405 134 136 −9 Klebsiella Contig560A GTC ORF with score 233 to: (ai:7000806518) pneumoniae (or:Pseudomonas aeruginosa) 33204003_c2_1580 3119 19690 558 185 134 −8 Mycobacterium U15180 (de:mycobacterium leprae cosmid b1756.) lepiae 26660402_c2_1581 3120 19691 666 221 173 −12 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 31929131_c2_1590 3121 19692 1278 425 9869781_c2_1593 3122 19693 618 205 174 −12 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 34509592_c3_1605 3123 19694 867 288 156 −9 Klebsiella Contig539A GTC ORF with score 156 to: (ai:7000767219) pneumoniae (or:Pseudomonas aeruginosa) 13173316_c3_1609 3124 19695 939 312 295 −26 Klebsiella Contig542A GTC ORF with score 347 to: (ai:7000823199) pneumoniae (or:Enterobacter cloacae) 36431575_c3_1614 3125 19696 549 182 154 −11 Achromobacter JC1119 georgiopolitanum 12760216_c3_1616 3126 19697 3204 1067 817 −81 Escherichia coli P27296 (de:probable atp-dependent helicase ding (dna- damage-inducible protein g)) 2626041 _c3_1617 3127 19698 2352 783 917 −92 Vibrio sp. P48840 (sr:jt0107,) (ec:3.2.1.81) (de:beta-agarase b,) 21503816_c3_1623 3128 19699 663 220 99 −3 Aspergillus Contig1907 GTC ORF with score 134 to: (ai:7000757549) fumigatus (or:Pseudomonas aeruginosa) 4884701_c3_1628 3129 19700 1149 382 977 −98 Bacillus P42100 (de:hypothetical 39.4 kd protein in gntr-htpg subtilis/Bacillus intergenic region) globigii 6728760_c3_1629 3130 19701 498 165 289 −25 Salmonella Q53549 (de:outer membrane lipoprotein slyb choleraesuis precursor) serotype typhimurium 17086006_c3_1631 3131 19702 1893 630 211 −13 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 14314532_c3_1632 3132 19703 366 121 296 −26 Rhizobium meliloti X93358 (de:r.meliloti pha(a,b,c,d,e,f,g) genes.) (megaplasmid pRME41B SYM) 5985140_c3_1635 3133 19704 720 239 204 −16 Rhizobium meliloti X93358 (de:r.meliloti pha(a,b,c,d,c,f,g) genes.) (megaplasmid pRME41B SYM) 10004180_c3_1636 3134 19705 1134 377 310 −28 Bacillus C69749 subtilis/Bacillus globigii 13755041_c3_1641 3135 19706 612 203 199 −16 Klebsiella Contig134A GTC ORF with score 199 to: (ai:7000767255) pneumoniae (or:Pseudomonas aeruginosa) 10720655_c3_1642 3136 19707 957 318 437 −41 Bradyrhizobium AF007569 (de:bradyrhizobium japonicum gstr (gstr) gene, japonicum partial cds, andsuccinate dehydrogenase membrane anchor subunit (sdhc), membraneanchor subunit (sdhd), flavoprotein subunit (sdha) and iron-sulfurprotein subunit (sdhb) genes, complete c . . . 10824093_c3_1648 3137 19708 363 120 117 −7 Aspergillus Contig8669 GTC ORF with score 160 to: (ai:5500691725) fumigatus (or:Santalum album) (sr:white sandalwood) (de:santalum album proline rich protein mrna, complete cds.) 9775843_c3_1650 3138 19709 765 254 93 −2 Mycobacterium AF027770 (de:mycobacterium smegmatis iron uptake smegmatis genes, fxba (fxba) gene,partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf)genes, complete cds.) (nt:similar to membrane b . . . 34239505_c3_1654 3139 19710 552 183 192 −15 Klebsiella Contig397A GTC ORF with score 587 to: (ai:7000836507) pneumoniae (or:Enterobacter cloacae) 35980138_c3_1655 3140 19711 528 175 130 −9 Klebsiella Contig397A GTC ORF with score 587 to: (ai:7000836507) pneumoniae (or:Enterobacter cloacae) 12117650_c3_1657 3141 19712 645 214 117 −4 Arabidopsis thaliana AC000098 (sr:thale cress) (de:arabidopsis thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts1136 comes from this gene.) 9819433_c3_1658 3142 19713 444 147 148 −9 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem- 11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 22917016_c3_1660 3143 19714 771 256 105 −3 African malaria S27770 (sr:, african malaria mosquito) mosquito 12292662_c3_1664 3144 19715 810 269 792 −79 Salmonella P16439 (de:flagellar basal-body rod protein flgg (distal choleraesuis rod protein)) serotype typhimurium 24642251_c3_1665 3145 19716 702 233 594 −58 Pseudomonas putida Q52081 (de:flagellar l-ring protein precursor (basal body l-ring protein)) 25995380_c3_1667 3146 19717 1218 405 396 −37 Vibrio cholerae AF019213 (de:vibrio cholerae flgi (flgi) gene, partial cds; and flagellarprotein (flgj), hook associated protein (flgm), hook associatedprotein (flgl), and flagellin core protein a (flaa) genes, completecds.) (nt:similar to s. typhimurium flg . . . 25869031_c3_1668 3147 19718 2052 683 627 −61 Escherichia coli G64851 (cl:flagellar hook-associated protein 1) 14536282_c3_1669 3148 19719 510 169 128 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16488183_c3_1670 3149 19720 567 188 127 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 16042805_c3_1671 3150 19721 1119 372 106 −2 mice|C57BL/6xCBA/ U30292 (sr:house mouse) (de:mus musculus collagen Cal hybrid type xiii alpha-1 chain mrna, complete cds.) 25444431_c3_1673 3151 19722 654 217 201 −16 Bacillus E70037 subtilis/Bacillus globigii 24612942_c3_1678 3152 19723 1287 428 11988458_c3_1680 3153 19724 603 200 36348843_c3_1695 3154 19725 1254 417 1884 −194 Pseudomonas AF034764 (de:pseudomonas aeruginosa flagellin gene, aeruginosa partial cds.) 16839042_c3_1698 3155 19726 1443 480 2352 −244 Pseudomonas L81176 (de:pseudomonas aeruginosa flagellin (flic), aeruginosa flag (flag), flagellar cap(flid), and flis (flis) genes, complete cds.) (nt:flid) 4113456_c3_1699 3156 19727 426 141 622 −61 Pseudomonas L81176 (de:pseudomonas aeruginosa flagellin (flic), aeruginosa flag (flag), flagellar cap(flid), and flis (flis) genes, complete cds.) (nt:orf 126; similar to flis) 12162558_c3_1701 3157 19728 1536 511 2493 −259 Pseudomonas L43064 (fn:regulation/activation) (sr:pseudomonas aeruginosa aeruginosa (strain dg 1) dna) (de:pseudomonas aeruginosa flis, orf4, and regulatory protein (orf5)genes, complete cds, regulatory protein (orf6) and flagellum capprotein (flid) genes, partial cds . . . 26428841_c3_1703 3158 19729 972 323 178 −11 Globodera pallida X96713 (de:g.pallida mrna for collagen.) (nt:putative) 34510130_c3_1705 3159 19730 504 167 157 −12 Enterobacter cloacae CONTIG504 GTC ORF with score 281 to: (ai:7501777202) (or:Klebsiella pneumoniae) 25915900_c3_1708 3160 19731 1800 599 2974 −9999 Pseudomonas Q51463 (de:flagellar m-ring protein) aeruginosa 9853765_c3_1709 3161 19732 297 98 105 −5 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 7089130_c3_1710 3162 19733 813 270 174 −13 Escherichia coli P31068 (de:flagellar assembly protein flih) 1348458_c3_1711 3163 19734 1560 519 223 −17 Streptococcus CONTIG811 GTC ORF with score 703 to: (ai:5500687212) pneumoniae D (or:Pseudomonas aeruginosa) (de:pseudomonas aeruginosa pscn (pscn) gene, complete cds, and psco(psco) gene, partial cds.) 2479131_c3_1719 3164 19735 1830 609 370 −33 Escherichia coli P75804 (de:hypothetical 41.1 kd protein in moca-dacc intergenic region precursor) 11188287_c3_1727 3165 19736 1065 354 115 −3 Caenorhabditis Z75539 (de:caenorhabditis elegans cosmid f28c1, elegans complete sequence.) (nt:predicted using genefinder; cdna est embl:c13354) 5909662_c3_1734 3166 19737 795 264 107 −6 Klebsiella Contig549A GTC ORF with score 107 to: (ai:7000767348) pneumoniae (or:Pseudomonas aeruginosa) 4308290_c3_1738 3167 19738 789 262 110 −3 Nephila clavipes U20329 (fn:spider silk) (de:nephila clavipes spidroin 1 mrna, partial cds.) (nt:fibroin) 2539836_c3_1746 3168 19739 1503 500 171 −9 Homo sapiens M58526 (sr:human cdna to mrna) (de:human alpha-5 collagen type iv (co4a5) mrna, 3′ end.) 4375082_c3_1749 3169 19740 1266 421 14979155_c3_1752 3170 19741 471 156 379 −35 Escherichia coli A60635 (c1:fosfomycin resistance protein) (ec:2.5.1.18) 15679778_c3_1756 3171 19742 576 191 178 −12 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-carlygenes.) (nt:similar to hhv6a u86, region ie-b) 9816683_c3_1761 3172 19743 564 187 127 −8 Aspergillus Contig9870 GTC ORF with score 146 to: (ai:7000722943) fumigatus (or:Human herpesvirus 6) (fn:helicase, helicase primase complex) (de:human herpesvirus 6 serotype b putative major immediate- earlygenes.) (nt:similar to hhv6a u86, region ie- b) 10804155_c3_1769 3173 19744 489 162 142 −9 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 34550791 _c3_1772 3174 19745 1629 542 160 −9 Klebsiella Contig558A GTC ORF with score 983 to: (ai:7000841379) pneumoniae (or:Enterobacter cloacae) 14703958_c3_1780 3175 19746 441 146 107 −4 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 36042782_c3_1782 3176 19747 519 172 93 −2 no gb taxonomy P08393 (sr:type 1/17,) (de:ie110) (vmw110) (alpha-0 match protein)) 22165890_c3_1783 3177 19748 2001 666 4084713_c3_1787 3178 19749 1866 621 3133 −9999 Pseudomonas A36907 aeruginosa 20907808_c3_1788 3179 19750 510 169 34460881_c3_1796 3180 19751 1707 568 35369758_c3_1807 3181 19752 990 329 177 −11 Globodera pallida X96713 (de:g.pallida mrna for collagen.) (nt:putative) 32661432_c3_1813 3182 19753 1536 511 447 −42 Enterobacter cloacae CONTIG511 GTC ORF with score 837 to: (ai:7501786250) (or:Klebsiella pneumoniae) 32710433_c3_1823 3183 19754 213 70 5321925_c3_1825 3184 19755 504 167 34464717_c3_1828 3185 19756 1308 435 120 −3 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 6362581_c3_1829 3186 19757 1221 406 374 −34 Haemophilus AB010415 (sr:actinobacillus actinomycetemcomitans actinomycetem- (str:nctc9710) dna) (de:actinobacillus comitans actinomycetemcomitans gene cluster for6- deoxy-1-talan synthesis, complete cds.) (nt:orf5) 16886581_c3_1830 3187 19758 2691 896 135 −5 Klebsiella Contig506A GTC ORF with score 649 to: (ai:7000834773) pneumoniae (or:Enterobacter cloacae) 15647032_c3_1832 3188 19759 786 261 1031 −104 Pseudomonas A44762 aeruginosa 32167932_c3_1833 3189 19760 1956 651 574 −56 Salmonella B32932 (cl:envz protein:sensor histidine kinase choleraesuis homology) (mp:25 min) serotype typhimurium 16292555_c3_1836 3190 19761 717 238 124 −5 equine herpesvirus P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) type 1 EVH-1 33673958_c3_1843 3191 19762 1386 461 277 −24 Klebsiella Contig481A GTC ORF with score 277 to: (ai:7000767457) pneumoniae (or:Pseudomonas aeruginosa) 15755280_c3_1845 3192 19763 654 217 404 −37 Escherichia coli P77526 (de:hypothetical 24.5 kd protein in pta-folx intergenic region) 3302137_c3_1854 3193 19764 951 316 331 −30 Klebsielia Contig560A GTC ORF with score 331 to: (ai:7000767468) pneumoniae (or:Pseudomonas aeruginosa) 32598916_c3_1855 3194 19765 1566 521 92 −1 Dictyostelium AJ224893 (fn:spore differentiation) (de:dictyostelium discoideum discoideum srfa gene.) 32604132_c3_1858 3195 19766 213 70 98 −5 Klebsiella Contig329A GTC ORF with score 107 to: (ai:7000764020) pneumoniae (or:Pseudomonas aeruginosa) 16900283_c3_1865 3196 19767 846 281 538 −52 Legionella AF075724 (de:legionella pneumophila legiolysin(lly) pneumophila gene, complete cds; andunknown genes.) (nt:orf1) 16063527_c3_1869 3197 19768 522 173 90 −2 domestic horse P37998 (sr:,horse) (de:t-cell surface antigen cd2 precursor) 31500266_c3_1870 3198 19769 774 257 103 −5 Escherichia coli P24246 (de:hypothetical 14.5 kd protein in prkb-crp intergenic region (f134)) 22770782_c3_1871 3199 19770 585 194 395 −37 Escherichia coli P31465 (de:hypothetical 20.4 kd protein in tnab-bglb intergenic region) 34650681_c3_1876 3200 19771 765 254 149 −7 Homo sapiens L23982 (sr:homo sapiens (tissue library: lambda embl3, lambda fix) placent) (de:homo sapiens (clones: cw52-2, cw27-6, cw15-2, cw26-5, 11- 67)collagen type vii intergenic region and (col7a1) gene. completecds.) 12234667_c3_1879 3201 19772 321 106 107 −5 Homo sapiens S53363 (sr:,man) (mp:11p15.5-11p15.5) 31878930_c3_1880 3202 19773 342 113 90 −5 Klebsiella Contig544A GTC ORF with score 140 to: (ai:380588) pneumoniae (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 14972706_c3_1881 3203 19774 1233 410 112 −6 Klebsiella Contig487A GTC ORF with score 126 to: (ai:163272) pneumoniae (or:Escherichia coli) (mp:11.1 min) 36049182_c3_1884 3204 19775 570 189 102 −4 Klebsiella Contig438A GTC ORF with score 115 to: (ai:7000772235) pneumoniae (or:Pseudomonas aeruginosa) 26739826_c3_1885 3205 19776 1140 379 150 −7 African clawed frog U85970 (sr:african clawed frog) (de:xenopus laevis middle molecular weight neurofilament proteinnf-m(2) mrna, complete cds.) (nt:neuronal intermediate filament protein; duplicated) 31532182_c3_1888 3206 19777 699 232 132 −7 Orf virus D34768 31886412_c3_1891 3207 19778 2298 765 12586387_c3_1897 3208 19779 555 184 96 −2 Nephila clavipes U37520 (de:nephila clavipes dragline silk protein spidroin 1 gene, partialcds.) 22159541 _c3_1898 3209 19780 1413 470 16586683_c3_1911 3210 19781 402 133 196 −16 Klebsiella Contig556A GTC ORF with score 196 to: (ai:7000767525) pneumoniae (or:Pseudomonas aeruginosa) 12207330_c3_1914 3211 19782 1002 333 149 −8 Enterococcus U51479 (de:enterococcus gallinarum gentamicin gallinarum resistance protein gene,complete cds.) (nt:similar with 2″-aminoglycoside phosphotransferase) 11922556_c3_1915 3212 19783 1455 484 141 −9 Klebsiella Contig500A GTC ORF with score 141 to: (ai:7000767529) pneumoniae (or:Pseudomonas aeruginosa) 16835441_c3_1916 3213 19784 2640 879 211 −23 Escherichia coli P46481 (de:hypothetical 73.6 kd protein in argr-cafa intergenic region (f655)) 15916632_c3_1920 3214 19785 2031 676 115 −3 Saimiriine Q01042 (sr:11,) (de:immediate-early protein) herpesvirus 2 2189841_f1_3 3215 19786 606 201 128 −6 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpesvirus papio brrf2 homolog gene, partial cds, ebna 1, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebna 1 of epstein-barr v . . . 21586392_fl_13 3216 19787 939 312 95 −3 Klebsiella Contig349A GTC ORF with score 149 to: (ai:7000836613) pneumoniae (or:Enterobacter cloacae) 25494643_f1_14 3217 19788 1551 516 112 −3 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 10197503_f1_16 3218 19789 1044 347 436 −41 Escherichia coli P75745 (de:hypothetical 34.4 kd protein in phrb-nei intergenic region) 31416412_f1_19 3219 19790 210 69 2392530_f1_20 3220 19791 1182 393 1262 −128 Escherichia coli P12996 (ec:2.8.1.6) (de:biotin synthase, (biotin synthetase)) 24848181_f1_21 3221 19792 1311 436 821 −82 Erwinia herbicola Q47829 (ec:2.3.1.47) (de:ligase)) 14864441 _f1_23 3222 19793 603 200 104 −3 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14317831_f1_28 3223 19794 306 101 127 −8 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline- rich cell wall protein mrna, completecds.) 16277266_f1_32 3224 19795 1200 399 32527007_f1_33 3225 19796 1863 620 769 −76 Acinetobacter sp. L05770 (de:acinetobacter sp. adp1 pca-qui-pob ADP1 supraoperonic cluster, completesequence.) (nt:encodes protein similar to acyl-coa dehydrogenase) 16033340_f1_34 3226 19797 1623 540 35816682_f1_39 3227 19798 909 302 107 −3 Caenorhabditis Z92826 (de:caenorhabditis elegans cosmid c18d11, elegans complete sequence.) (nt:similar to rna recognition motif. (aka rrm, rbd, or) 2227013_f1_48 3228 19799 912 303 155 −8 Nephila clavipes AF027973 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 35291280_f1_49 3229 19800 405 134 183 −14 Pseudomonas Q51483 (de:hypothetical 9.1 kd protein in nirq 3′region aeruginosa (orf3)) 10736576_f1_50 3230 19801 534 177 785 −78 Pseudomonas S53712 (ec:1.7.99.7) aeruginosa 16300633_f1_52 3231 19802 1869 622 3181 −9999 Pseudomonas S53714 aeruginosa 4536505_f1_57 3232 19803 741 246 434 −41 Escherichia coli P32157 (de:hypothetical 26.6 kd protein in kdgt-cpxa intergenic region (o234)) 25525337_f1_58 3233 19804 1173 390 652 −64 Pseudomonas AF011922 (de:pseudomonas aeruginosa aru gene cluster, aeruginosa argr regulatory protein(argr) succinylornithine aminotransferase (aruc),arginine/ornithine succinyltransferase ai subunit (aruf),arginine/ornithine succinyltransferase aii subunit (arug) . . . 31925756_f1_62 3234 19805 1965 654 238 −16 domestic horse U62528 (sr:domestic horse) (de:equus caballus type ii collagen mrna, complete cds.) 25885937_f1_67 3235 19806 1047 348 121 −5 Chlamydomonas S19114 reinhardtii strain UTEX 1061 2620312_f1_73 3236 19807 474 157 17056967_f1_75 3237 19808 474 157 775 −77 Staphylococcus CONTIG005 GTC ORF with score 775 to: (ai:7000767614) epidermidis C (or:Pseudomonas aeruginosa) 16894156_f1_76 3238 19809 255 84 437 −41 Staphylococcus CONTIG005 GTC ORF with score 437 to: (ai:7000767615) epidermidis C (or:Pseudomonas aeruginosa) 24713567_f1_81 3239 19810 1470 489 811 −81 Klebsiella Contig526A GTC ORF with score 1384 to: pneumoniae (ai:7000844444) (or:Enterobacter cloacae) 31698910_fl_84 3240 19811 2229 742 2608 −271 Escherichia coli P27302 (ec:2.2.1.1) (de:transketolase 1, (tk 1)) 7211026_f1_88 3241 19812 759 252 167 −13 Klebsiella Contig341A GTC ORF with score 167 to: (ai:7000767627) pneumoniae (or:Pseudomonas aeruginosa) 13944680_f1_92 3242 19813 1191 396 1404 −143 Haemophilus D64074 (cl:phosphoglycerate kinase) (ec:2.7.2.3) influenzae 36586541_f1_93 3243 19814 273 90 13163586_f1_94 3244 19815 426 141 12619432_f1_95 3245 19816 888 295 103 −4 Aspergillus v3x15c18.y GTC ORF with score 152 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 31734506_f1_96 3246 19817 909 302 380 −35 Mycobacterium AL021841 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 143/162.) (nt:rv3342, (mtv016.42), len: 243. unknown but some) 16285466_f1_100 3247 19818 828 275 555 −53 Escherichia coli P42597 (de:hypothetical 20.9 kd protein in ebgc-uxaa intergenic region (o179)) 16058336_f1_107 3248 19819 456 151 100 −3 Caenorhabditis U53333 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid f36a4.) (nt:coded for by c. elegans cdna yk120g12.5; similar to) 14648541_f1_111 3249 19820 222 73 183 −14 Cyanobacterium P74805 (sr:pcc 6803,) (de:hypothetical 9.1 kd protein synechocystis ssr1169) 10394543_f1_112 3250 19821 1395 464 95 −3 Aspergillus Contig6523 GTC ORF with score 129 to: (ai:148203) fumigatus (or:Drosophila melanogaster) (c1:helix- destabilizing protein :ribonucleoprotein repeat homology) 29586041_f1_115 3251 19822 1893 630 22786331_f1_116 3252 19823 663 220 103 −3 Streptomyces AL031013 (de:streptomyces coelicolor cosmid 8a6.) coelicolor (nt:sc8a6.21c, probable transcriptional regulator, :) 16025452_f1_119 3253 19824 204 67 10393903_f1_130 3254 19825 774 258 108 −3 human herpesvirus X83413 (de:human herpesvirus-6 (hhv-6) u1102, type 6 HHV-6 variant a, complete viriongenome.) (nt:cys repeats; this loci is open in all six reading) 32598586_f2_132 3255 19826 831 276 375 −35 Klebsiella Contig534A GTC ORF with score 447 to: (ai:7000828776) pneumoniae (or:Enterobacter cloacae) 9792831_f2_135 3256 19827 1134 377 178 −12 Klebsiella Contig474A GTC ORF with score 178 to: (ai:7000767674) pneumoniae (or:Pseudomonas aeruginosa) 17056418_f2_140 3257 19828 771 256 540 −52 Pyrococcus AP000004 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna 777001-994000 nt. position(4/7).) (nt:similar to :af0060004 percent ident: 48.980) 29927182_f2_142 3258 19829 1362 453 1156 −117 Pseudomonas P37798 (ec:6.3.4.14:6.4.1.2) (de:carboxylase,) (acc)) aeruginosa 9897840_f2_153 3259 19830 987 328 247 −21 Escherichia coli P13001 (de:bioh protein) 5985213_f2_154 3260 19831 1434 477 171 −9 Strongylocentrotus S23809 (cl:collagen alpha 2(i) chain:fibrillar collagen purpuratus carboxyl-terminal homology) (sr:, purple urchin) 14195427_f2_155 3261 19832 423 140 105 −6 Klebsiella Contig471A GTC ORF with score 306 to: (ai:7000774112) pneumoniae (or:Pseudomonas aeruginosa) 5367626_f2_160 3262 19833 1845 614 938 −94 Acinetobacter sp. L05770 (de:acinetobacter sp. adp1 pca-qui-pob ADP1 supraoperonic cluster, completesequence.) (nt:encodes protein similar to acyl-coa dehydrogenase) 31893955_f2_176 3263 19834 846 281 112 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna partialcds.) 26822163_f2_181 3264 19835 786 261 1347 −137 Pseudomonas Q51481 (de:denitrification regulatory protein nirq) aeruginosa 29931706_f2_183 3265 19836 210 69 257 −22 Pseudomdnas Q51483 (de:hypothetical 9.1 kd protein in nirq 3′region aeruginosa (orf3)) 17051957_f2_184 3266 19837 1626 541 29885407_f2_185 3267 19838 654 217 149 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26064787_f2_191 3268 19839 771 256 129 −6 Klebsiella Contig482A GTC ORF with score 172 to: (ai:7000809604) pneumoniae (or:Pseudomonas aeruginosa) 26777041_f2_198 3269 19840 222 73 21735915_f2_200 3270 19841 1572 523 206 −13 Cyanobacterium S76989 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 32672908_f2_204 3271 19842 1062 353 152 −10 Azotobacter U94420 (de:azotobacter vinelandii aldehyde vinelandii dehydrogenase (aldh) gene, partialcds, cytochrome c5 (cycb) gene, complete cds, and xanthinephosphoribosyltransferase-like protein (xrpt) gene, partial cds.) 7050257_f2_211 3272 19843 543 180 100 −4 Klebsiella Contig542A GTC ORF with score 298 to: (ai:7000845362) pneumoniae (or:Enterobacter cloacae) 11724141_f2_217 3273 19844 819 272 1234 −126 Staphylococcus CONTIG005 GTC ORF with score 1234 to: epidermidis C (ai:7000767756) (or:Pseudomonas aeruginosa) 12972067_f2_223 3274 19845 681 226 133 −6 Escherichia coli D90774 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 104200_f2_233 3275 19846 1104 367 914 −92 Escherichia coli P11603 (ec:1.2.1.—) (de:d-erythrose 4-phosphate dehydrogenase, (e4pdh)) 26355192_f2_240 3276 19847 1284 427 6914756_f2_247 3277 19848 1197 398 31489506_f2_249 3278 19849 1566 521 36364567_f2_250 3279 19850 429 142 370 −34 Haemophilus Q57498 (de:hypothetical protein hi1053) influenzae 32163506_f2_262 3280 19851 363 120 16489656_f3_277 3281 19852 1515 504 13022930_f3_279 3282 19853 732 243 147 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein prccursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4346943_f3_280 3283 19854 258 85 178 −14 Haemophilus P43874 (ec:6.4.1.2) (de:(ec 6.4.1.2) (bccp)) influenzae 7066330_f3_282 3284 19855 1080 359 143 −8 Escherichia coli P75744 (de:hypothetical 23.9 kd protein in phrb-nei intergenic region) 16579143_f3_283 3285 19856 783 260 114 −3 Gibberella fujikuroi P78688 (sr:,gibberella fujikuroi) (de:nitrogen regulation protein area) 29792640_f3_292 3286 19857 1221 406 109 −3 mice|C57BL/6xCBA/ AF079527 (sr:house mouse) (de:mus musculus ier5 (ier5) Caj hybrid mrna, complete cds.) 16019388_f3_294 3287 19858 846 281 512 −49 Serratia marcescens P36571 (de:biotin synthesis protein bioc) 16900282_f3_295 3288 19859 690 229 532 −51 Erwinia herbicola U51208 (de:erwinia herbicola dethiobiotin synthetase (biod) gene, completecds.) 4900467_f3_296 3289 19860 234 77 15743842_f3_297 3290 19861 1818 605 1090 −110 Acinetobacter sp. L05770 (de:acinetobacter sp. adp1 pca-qui-pob ADP1 supraoperonic cluster, completesequence.) (nt:encodes protein similar to acyl-coa dehydrogenase) 35808293_f3_306 3291 19862 654 217 131 −6 Streptomyces P2010186 (de:hypothetical 35.5 kd protein in transposon fradiae tn4556) 221347l7_f3_307 3292 19863 846 281 329 −30 Klebsiella Contig413A GTC ORF with score 577 to: (ai:7000828496) pneumoniae (or:Enterobacter cloacae) 32672915_f3_313 3293 19864 1662 553 599150_f3_315 3294 19865 1359 452 11022840_f3_319 3295 19866 591 196 933 −94 Pseudomonas JC2289 aeruginosa 14317637_f3_320 3296 19867 1872 623 2446 −254 Pseudomonas Q59647 (ec:1.7.99.7) (de:(nor)) aeruginosa 31271013_f3_321 3297 19868 729 242 123 −4 Rana catesbeiana D88764 (sr:rana catesbeiana larva tail cdna to mrna) (de:rana catesbeiana mrna for alpha 2 type collagen, complete cds.) 31379131_f3_322 3298 19869 2283 760 136 −4 equine herpesvirus AF030027 (fn:very large tegument protein) (de:equine type 4 EHV-4 herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene ul36 and vzv gene 22) 31504757_f3_326 3299 19870 429 142 25494756_f3_327 3300 19871 1878 625 492 −47 Cyanobacterium S75988 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 34505206_f3_331 3301 19872 501 166 96 −2 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 6328_f3_332 3302 19873 1338 445 790 −78 Escherichia coli P37906 (ec:1.—.—.—) (de:probable oxidoreductase ord1,) 5161563_f3_338 3303 19874 1635 544 97 −3 Pseudomonas P29939 (de:hypothetical 15.0 kd protein in cobo denitrificans 3′region (orf6)) 11772878_f3_339 3304 19875 417 138 219 −18 Acinetobacter CONTIG186 GTC ORF with score 219 to: (ai:7000767878) baumannii C (or:Pseudomonas aeruginosa) 24089686_f3_342 3305 19876 1122 373 319 −28 Mycobacterium U00012 (de:mycobacterium leprae cosmid b1308.) leprae 23475968_f3_345 3306 19877 1374 457 157 −8 Methylosinus C48360 (ec:1.14.13.25) trichosporium 32681408_f3_348 3307 19878 330 109 140 −9 mice|C57BL/6xCBA/ C29149 (cl:proline-rich protein) (sr:, house mouse) Caj hybrid 22126413_f3_354 3308 19879 2007 668 173 −12 Klebsiella Contig545A GTC ORF with score 173 to: (ai:7000767893) pneumoniae (or:Pseudomonas aeruginosa) 16297941_f3_360 3309 19880 471 156 151 −10 Burkholderia U41162 (sr:burkholderia cepacia strain=17616) cepacia (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 32519707_f3_365 3310 19881 1095 364 1304 −133 Xanthobacter flavus U29134 (ec:4.1.13) (de:xanthobacter flavus transketolase (cbbt) and class iifructose-1,6- bisphosphate aldolase (cbba) genes, complete cds, andpentose-5-phosphate-3-epimerase (cbbe) gene, partial cds.) 35284816_f3_369 3311 19882 1758 585 293 −25 Enterobacter cloacae CONTIG451 GTC (ORF with score 389 to: (ai:7501738882) (or:Klebsiella pneumoniae) 13025827_f3_377 3312 19883 405 134 106 −4 Molluscum L10127 (sr:molluscum contagiosum virus type 1 dna) contagiosum virus (de:molluscum contagiosum virus type 1 orf1 subtype 1 and orf2 dna.) (nt:orf17) 13161542_f3_381 3313 19884 1452 483 26804812_c1_398 3314 19885 576 191 185 −13 Schizo- Q10475 (sr:,fission yeast) (de:probable eukaryotic saccharomyces initiation factor c17c9.03) pombe 34413586_c1_405 3315 19886 2532 843 36151958_c1_406 3316 19887 234 77 16141936_c1_407 3317 19888 2808 935 15745791_c1_409 3318 19889 558 185 12777307_c1_410 3319 19890 474 157 26183581_c1_417 3320 19891 1020 339 119 −4 Orf virus B34768 26197711_c1_419 3321 19892 573 190 266 −23 Klebsiella Contig548A GTC ORF with score 410 to: (ai:7000843055) pneumoniae (or:Enterobacter cloacae) 26807958_c1_420 3322 19893 1995 664 1413328_c1_425 3323 19894 1371 456 233 −17 Klebsiella Contig526A GTC ORF with score 1412 to: pneumoniae (ai:7000844111) (or:Enterobacter cloacae) 2551001_c1_426 3324 19895 720 239 459 −44 Klebsiella Contig526A GTC ORF with score 1412 to: pneumoniae (ai:7000844111) (or:Enterobacter cloacae) 30157912_c1_429 3325 19896 882 293 1001 −101 Ralstonia eutropha Q44015 (de:hypothetical 28.3 kd protein in gbd 5′region (orf4)) 31347906_c1_431 3326 19897 2709 902 100 −2 Homo sapiens A47234 (cl:unassigned homeobox proteins:homeobox homology) (sr:, man) 29480285_c1_432 3327 19898 1047 348 163 −9 Streptomyces fradiae P20187 (de:hypothetical 37.1 kd protein in transposon tn4556) 31839640_c1_433 3328 19899 1206 401 1475 −151 Haemophilus P43762 (ec:2.5.1.6) (de:adenosyltransferase) (adomet influenzae synthetase)) 12708208_c1_441 3329 19900 642 213 95 −1 mice|C57BL/6xCBA/ P97347 (sr:,mouse) (de:repetin) Caj hybrid 30208443_c1_446 3330 19901 426 141 112 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29425837_c1_449 3331 19902 513 170 374 −34 Treponema pallidum AE001232 (de:treponema pallidum section 48 of 87 of the complete genome.) (nt:similar to gb:x61227 pid:48231 percent ident:) 31900283_c1_450 3332 19903 1029 342 310 −38 Escherichia coli P55140 (de:hypothetical 34.9 kd protein in cysj-eno intergenic region (o313)) 13128956_c1_452 3333 19904 579 192 143 −10 Orf virus D34768 29578917_c1_460 3334 19905 759 252 136 −9 Crithidia fasciculata AF034951 (de:crithidia fasciculata h1 histone-like protein p21 (kap1) mrna,nuclear gene encoding kinetoplast protein complete cds.) (nt:highly- basic dna binding protein; targeted to; 2471078_c1_461 3335 19906 1122 373 255 −20 Klebsiella Contig560A GTC ORF wiih score 629 to: (ai:7000799453) pneumoniae (or:Pseudomonas aeruginosa) 36066041_c1_462 3336 19907 1197 398 106 −3 Homo sapiens AJ006692 (sr:human) (de:homo sapiens uhs kerb gene.) 4553192_c1_463 3337 19908 897 298 172 −11 Homo sapiens S10889 (cl:proline-rich protein) (sr:, man) 16487793_c1_465 3338 19909 1650 549 14708555_c1_467 3339 19910 1104 367 120 −3 Alphaherpesvirus P11675 (sr:indiana-funkhauser/becker,prv) pseudorabies virus (de:immediate-early protein ie180) PRV 21539587_c1_471 3340 19911 1377 458 2210753_cl _472 3341 19912 402 133 544 −52 Pseudomonas P00099 (de:cytochrome c-551 precursor (c551) aeruginosa (cytochrome c8)) 16147931 _c1_473 3342 19913 1587 528 762 −75 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 16150905_c1_475 3343 19914 603 200 762 −75 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 31375791_c1_476 3344 19915 1647 548 2032 −210 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 21589068_c1_477 3345 19916 2322 773 2579 −268 Pseudomonas D84475 (fn:unknown) (sr:pseudomonas aeruginosa aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) (nt:show high homology with nir protein) 26695206_c1_478 3346 19917 2154 717 31539531_c1_482 3347 19918 462 153 98 −5 Chironomus thummi A05231 33722951_c1_488 3348 19919 3150 1049 178 −9 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain uganda-1102) (type 6/strain ie2hom mrna, complete cds.) (nt:similar to the Uganda-1102) immediate-early 2 protein of human) 16596931_c1_489 3349 19920 1092 363 91 −1 Pseudomonas A36128 aeruginosa 6891068_c1_491 3350 19921 774 257 13781967_c1_492 3351 19922 1434 477 124 −7 Klebsiella Contig349A GTC ORF with score 182 to: (ai:7000789747) pneumoniae (or:Pseudomonas aeruginosa) 31458557_c1_504 3352 19923 1095 364 183 −14 Escherichia coli P46126 (de:hypothetical 9.9 kd protein in pssa-kgtp intergenic region) 9860205_c1_506 3353 19924 648 215 155 −10 Escherichia coli P32127 (de:hypothetical 38.1 kd protein in moba-dsba intergenic region) 22401588_c2_509 3354 19925 639 212 202 −16 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 23610215_c2_510 3355 19926 246 81 3925677_c2_511 3356 19927 1131 376 637 −62 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromaticivorans pn11, complete plasmidsequence.) (nt:similar to h. pylori plasmid phpm 180 hypothetical) 16413887_c2_512 3357 19928 864 287 200 −16 Enterobacter cloacae CONTIG228 GTC ORF with score 200 to: (ai:7000768051) (or:Pseudomonas aeruginosa) 14242151_c2_513 3358 19929 2736 911 3417826_c2_526 3359 19930 798 265 52283_c2_529 3360 19931 657 218 1266260_c2_530 3361 19932 1071 356 121 −5 white sandalwood AF020261 (sr:white sandalwood) (de:santalum album proline rich protein mrna, complete cds.) 21978406_c2_533 3362 19933 678 225 324 −29 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 20980033_c2_537 3363 19934 1317 438 1129 −114 Escherichia coli P37631 (de:hypothetical 43.8 kd protein in rhsb-pit intergenic region) 10292541_c2_539 3364 19935 708 235 35816693_c2_541 3365 19936 1368 455 10409713_c2_543 3366 19937 789 262 173 −13 Saccharomyces P25614 (sr:,baker's yeast) (de:very hypothetical 22.8 cerevisiae kd protein in pgk1 region) 13769632_c2_551 3367 19938 1329 442 34552080_c2_555 3368 19939 363 120 166 −13 Enterobacter cloacae CONTIG508 GTC ORF with score 166 to: (ai:7000768094) (or:Pseudomonas aeruginosa) 16917581_c2_561 3369 19940 1434 477 4776006_c2_562 3370 19941 825 274 32553783_c2_563 3371 19942 747 248 1219 −124 Staphylococcus CONTIG005 GTC ORF with score 1219 to: epidermidis C (ai:7000768102) (or:Pseudomonas aeruginosa) 30480408_c2_565 3372 19943 630 209 190 −15 Escherichia coli P42616 (de:hypothetical 14.5 kd protein in exur-tdcc intergenic region precursor) 29886325_c2_568 3373 19944 864 287 164 −9 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 16894005_c2_569 3374 19945 708 235 242 −20 Vibrio alginolyticus Q56578 (de:(fragment)) 16250790_c2_575 3375 19946 906 301 177 −11 Klebsiella Contig532A GTC ORF with score 632 to: (ai:7000771478) pneumoniae (or:Pseudomonas aeruginosa) 12316703_c2_576 3376 19947 432 143 107 −5 Klebsiella Contig532A GTC ORF with score 632 to: (ai:7000771478) pneumoniae (or:Pseudomonas aeruginosa) 14973941_c2_584 3377 19948 360 119 141 −10 Klebsiella Contig507A GTC ORF with score 193 to: (ai:7000827946) pneumoniae (or:Enterobacter cloacae) 12973900_c2_589 3378 19949 801 266 1149 −116 Pseudomonas S66482 aeruginosa 9855330_c2_592 3379 19950 423 140 125 −6 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain uganda-1102) (type 6/strain ie2hom mrna, complete cds.) (nt:similar to the Uganda-1102) immediate-early 2 protein of human) 26838532_c2_593 3380 19951 1923 640 31891667_c2_594 3381 19952 834 277 96 −1 Trypanosoma cruzi A44937 (cl:kinetoplast-associated protein) 16897183_c2_597 3382 19953 300 99 884657_c2_598 3383 19954 1710 569 2989 −9999 Pseudomonas P24474 (ec:1.9.3.2) (de:oxidase)) aeruginosa 22767662_c2_599 3384 19955 1842 613 2038 −211 Pseudomonas Q51480 (de:nirf protein) aeruginosa 30179213_c2_600 3385 19956 1002 333 177 −11 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29970682_c2_601 3386 19957 630 209 887 −89 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 10354165_c2_603 3387 19958 1452 483 1407 −144 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 12989687_c2_618 3388 19959 2115 704 2526416_c2_621 3389 19960 1470 489 111 −4 Klebsiella Contig549A GTC ORF with score 191 to: (ai:5500701468) pneumoniae (or:Equine herpesvirus 4) (fn:very large tegument protein) (de:equine herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene ul36 and vzv gene 22) 35782287_c2_622 3390 19961 792 263 135 −6 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 16212782_c2_626 3391 19962 879 292 222 −18 Escherichia coli L77091 (fn:stabilization of major subunit proteins) (sr:escherichia coli (individual_isolate natural isolate, strai) (de:escherichia coli f17d fimbrial gene cluster encoding the majorfimbrial subunit protein (f17d-a), the chaperone protein (f17d . . . 20525793_c2_627 3392 19963 1023 340 294 −26 Klebsiella Contig516A GTC ORF with score 294 to: (ai:7000768166) pneumoniae (or:Pseudomonas aeruginosa) 21508268_c2_638 3393 19964 1080 359 188 −12 Achromobacter A61183 georgiopolitanum 35285905_c2_639 3394 19965 327 108 31510280_c2_640 3395 19966 864 287 352 −32 Escherichia coli P46846 (de:hypotheticai 27.7 kd protein in bioh-gntt intergenic region (o243)) 21895941_c2_642 3396 19967 855 284 146 −8 Plasmodium vivax U08983 (de:plasmodium vivax isolate sol101 circumsporozoite protein gene,partial cds.) 32136376_c2_644 3397 19968 1707 568 109 −3 Homo sapiens S15079 (ci:vertebrate rhodopsin) (sr:, man) (mp:11p15.5-11p15.5) 23961061 _c3_645 3398 19969 633 210 165 −12 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 16489458_c3_659 3399 19970 693 230 35260380_c3_663 3400 19971 681 226 112 −4 Araneus diadematus U47854 (de:araneus diadematus fibroin-2 (adf-2) mrna, partial cds.) 11891705_c3_664 3401 19972 924 307 514 −49 Haemophilus P45008 (de:hypothetical transcriptional regulator infuenzae hi1052) 20207586_c3_665 3402 19973 450 149 267 −23 Escherichia coli P42622 (de:hypothetical 13.5 kd protein in exur-tdcc intergenic region) 26667716_c3_670 3403 19974 408 135 101 −4 Caenorhabditis U41746 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t18h9.) (nt:coded for by c. elegans cdna yk68a8.5) 12761380_c3_673 3404 19975 288 95 117 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 33844555_c3_680 3405 19976 519 172 108 −6 longfin squid S56117 (sr:, longfin squid) 2397561 _c3_682 3406 19977 1077 358 253 −22 Klebsiella Contig526A GTC ORF with score 355 to: (ai:7000844193) pneumoniae (or:Enterobacter cloacae) 36120776_c3_683 3407 19978 849 282 105 −2 Homo sapiens U75308 (sr:human) (de:human tbp-associated factor (htafii130) mrna, partial cds.) (nt:the c- terminal region is similar to drosophila) 34242066_c3_684 3408 19979 417 138 96 −3 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene domesticus coding for phosvitin, exons 23 and24.) 33828916_c3_687 3409 19980 513 170 126 −7 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 35205213_c3_690 3410 19981 552 183 129 −6 wildebeest AF005370 (sr:wildebeest herpesvirus) (de:alcelaphine herpesvirus herpesvirus 1 l-dna complete sequence) (nt:orf73; similar to, h. saimiri and kshv orf73) 30339656_c3_697 3411 19982 627 208 130 −6 Arabidopsis thaliana AC000098 (sr:thale cress) (de:arabidopsis thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts1136 comes from this gene.) 16255405_c3_698 3412 19983 237 78 401 −37 Staphylococcus CONTIG005 GTC ORF with score 401 to: (ai:7000768237) epidermidis C (or:Pseudomonas aeruginosa) 14956262_c3_714 3413 19984 2325 774 3932688_c3_722 3414 19985 888 295 358 −33 Escherichia coli P27111 (de:cyn operon transcriptional activator) 16914665_c3_728 3415 19986 933 310 179 −10 Chinese oak AF083334 (sr:chinese oak silkmoth) (de:antheraea pernyi silkmoth fibroin gene, complete cds.) 11724183_c3_729 3416 19987 522 173 144 −9 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) aeruginosa 12753930_c3_737 3417 19988 774 257 638 −62 Pseudomonas Q51479 (de:c-type cytochrome c55x precursor) 16882292_c3_740 3418 19989 1059 352 909 −91 Pseudomonas D84475 (fn:essential for biosynthesis of heme d1) aeruginosa (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa dna for nird, nirl, nirg, nirh,nirj,methyltransferase, nirn, complete and partial cds.) 16899067_c3_743 3419 19990 1218 405 110 −2 Alphaherpesvirus P33485 (sr:kaplan,prv) (de:probable nuclear antigen) pseudorabies virus PRV 16885080_c3_745 3420 19991 2364 787 147 −7 Homo sapiens S80905 (sr:human subject “r.s.” peripheral blood leukocytes) (de:prb2 (prb21 con1+)=con1 {exon 3} (human, peripheral bloodleukocytes, subject ‘r.s.’, genomic mutant, 1179 nt).) (nt:salivary concanavalin-a binding protein; method:) 3224063_c3_747 3421 19992 1203 400 16442930_c3_753 3422 19993 1173 390 109 −2 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 10642542_c3_758 3423 19994 420 139 107 −5 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 20995886_c3_764 3424 19995 468 155 139 −9 Klebsiella Contig516A GTC ORF with score 294 to: (ai:7000768166) pneumoniae (or:Pseudomonas aeruginosa) 16806591_c3_771 3425 19996 858 285 268 −23 Enterobacter cloacae CONTIG360 GTC ORF with score 651 to: (ai:7000792986) (or:Pseudomonas aeruginosa) 6534775_c3_772 3426 19997 480 159 158 −11 Enterobacter cloacae CONTIG360 GTC ORF with score 651 to: (ai:7000792986) (or:Pseudomonas aeruginosa) 36431712_c3_774 3427 19998 945 314 147 −10 Enterobacter cloacae CONTIG484 GTC ORF with score 248 to: (ai:7501736005) (or:Klebsiella pneumoniae) 9923 127_c3_775 3428 19999 975 324 302 −27 Xanthomonas U94336 (fn:required for the induction of a regulon of) campestris (de:xanthomonas campestris alkyl hydroperoxide reductase subunits c(ahpc) and f (ahpf) and oxidative stress transcriptional regulator(oxyr) genes, complete cds.) (nt:belongs to the lvsr . . . 10630383_c3_777 3429 20000 417 138 103 −4 Molluscum U60315 (de:molluscum contagiosum virus subtype 1, contagiosum virus complete genome.) (nt:this protein is much subtype 1 longer at the n-terminus than) 22785382_c3_779 3430 20001 1179 392 389 −36 Escherichia coli P46930 (de:molybdenum transport protein mode) 25781968_c3_780 3431 20002 1005 334 1114 −113 Pseudomonas Y11998 (de:p.fluorescens fc2.1, fc2.2, fc2.3c, fc2.4 and fluorescens fc2.5c open readingframes.) (nt:similar to e. coli orf o328 (sp:p32127)) 7210012_c3_781 3432 20003 969 322 1171 −119 Pseudomonas Y11998 (de:p.fluorescens fc2.1, fc2.2, fc2.3c, fc2.4 and fluorescens fc2.5c open readingframes.) (nt:similar to e. coli rard (sp:p27844)) 35061_f1_1 3433 20004 342 113 354 −32 Escherichia coli P37619 (de:hypothetical 25.3 kd protein in ftsy-nika intergenic region (o221)) 32439403_f1_2 3434 20005 243 80 10235436_f1_3 3435 20006 216 71 95 −5 Klebsiella Contig502A GTC ORF with score 95 to: (ai:7000768323) oo pneumoniae (or:Pseudomonas aeruginosa) 24878411_c3_13 3436 20007 243 80 33488843_f1_1 3437 20008 1116 371 328 −30 Klebsiella Contig355A GTC ORF with score 328 to: (ai:7000768334) pneumoniae (or:Pseudomonas aeruginosa) 23879077_f1_3 3438 20009 921 306 385 −35 Escherichia coli P52696 (de:hypothetical transcriptional regulator in mode-bioa intergenic region) 16300790_f1_5 3439 20010 1713 570 146 −7 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 31767025_f1_6 3440 20011 1218 405 167 −12 Mycobacterium AL022121 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 155/162.) (nt:rv3755c, (mtv025.103c), len: 199. unknown.) 12636416_f1_7 3441 20012 948 315 181 −12 Klebsiella Contig486A GTC ORF with score 181 to: (ai:7000768340) pneumoniae (or:Pseudomonas aeruginosa) 11206955_f1_10 3442 20013 438 145 111 −5 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 32425215_f1_11 3443 20014 1656 551 119 −4 African clawed frog S07498 (cl:dermal gland protein apeg:trefoil homology) (sr:, african clawed frog) 26438906_f1_12 3444 20015 675 224 101 −4 Aspergillus Contig9907 GTC ORF with score 215 to: (ai:307212) fumigatus (or:Volvox carteri) (de:v.carteri mrna for pherophorin-s.) 522933_f1_13 3445 20016 741 246 118 −4 minor jackknife L41834 (sr:ensis minor (clone: 1/6) male adult gonads clam cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 12558412_f1_20 3446 20017 693 230 317 −29 Enterobacter cloacae CONTIG513 GTC ORF with score 709 to: (ai:7501751403) (or:Klebsiella pneumoniae) 36149213_f2_22 3447 20018 465 154 105 −3 Rattus norvegicus U49056 (sr:norway rat) (de:rattus norvegicus ctd- binding sr-like protein ra1 mrna, completecds.) (nt:ctd-binding sr-like protein) 7120908_f2_23 3448 20019 426 141 554 −54 Klebsiella Contig355A GTC ORF with score 121 to: (ai:1500688476) pneumoniae (or:Sus scrofa domestica) (sr:, domestic pig) 11041466_f2_24 3449 20020 756 251 567 −55 Klebsiella Contig355A GTC ORF with score 567 to: (ai:7000768357) pneumoniae or:Pseudomonas aeruginosa) 34099083_f2_27 3450 20021 2127 708 1207 −123 Archaeoglobus E69274 fulgidus 26067667_f2_28 3451 20022 336 111 253 −21 Escherichia coli P39159 (ec:5.2.1.8) (de:(rotamase c) (parvulin)) 35660407_f2_29 3452 20023 375 124 6369778_f3 2_30 3453 20024 528 175 125 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4297881_f3_31 3454 20025 1281 426 965 −97 Escherichia coli P37621 (de:hypothetical 43.8 kd protein in ftsy-nika intergenic region (f419)) 10054183_f3_34 3455 20026 417 138 111 −5 Mycobacterium Z97991 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 17/162.) (nt:rv0338c, (mtcy279.05c), len: 882, unknown) 3400831_f3_36 3456 20027 564 187 181 −14 Klebsiella Contig507A GTC ORF with score 181 to: (ai:7000768369) pneumoniae (or:Pseudomonas aeruginosa) 30730211_f2_38 3457 20028 1317 438 30705430_f2_39 3458 20029 447 148 122 −8 Enterobacter cloacae CONTIG513 GTC ORF with score 212 to: (ai:7501751379) (or:Klebsiella pneumoniae) 16250808_f2_44 3459 20030 1029 342 110 −3 Homo sapiens U89278 (fn:interacts with the vertebrate polycomb- group) (sr:human) (de:human polyhomeotic 2 homolog (hph2) mrna, complete cds.) 36509655_f2_45 3460 20031 594 198 341 −31 Klebsiella Contig516A GTC ORF with score 421 to: (ai:7000809381) pneumoniae (or:Pseudomonas aeruginosa) 10417213_f3_46 3461 20032 438 145 126 −7 Rattus norvegicus A34615 (sr:, norway rat) 4867188_f3_48 3462 20033 1263 420 199 −13 Achromobacter A61183 georgiopolitanum 10276067_f3_51 3463 20034 606 201 151 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31336067_f3_58 3464 20035 1332 443 15742680_f3_60 3465 20036 417 138 98 −5 Aspergillus v3x12050.x GTC ORF with score 125 to: (ai:7000784256) fumigatus (or:Pseudomonas aeruginosa) 7057291_f3_64 3466 20037 717 238 506 −49 Enterobacter cloacae CONTIG513 GTC ORF with score 910 to: (ai:7501751402) (or:Klebsiella pneumoniae) 22864783_f3_65 3467 20038 519 172 208 −16 Enterobacter cloacae CONTIG513 GTC ORF with score 910 to: (ai:7501751402) (or:Klebsiella pneumoniae) 12213915_f3_66 3468 20039 1203 400 554 −54 Klebsiella Contig456A GTC ORF with score 554 to: (ai:7000768399) pneumoniae (or:Pseudomonas aeruginosa) 9875656_c1_71 3469 20040 648 215 781 −77 Pseudomonas P55172 (de:coenzyme pqq synthesis protein b) fluorescens 35282941_c1_72 3470 20041 1269 422 273 −23 Klebsiella P27506 (de:coenzyme pqq synthesis protein d) pneumoniae 17080212_c1_73 3471 20042 1200 399 15822831_c1_78 3472 20043 1221 406 878 −88 Methanobacterium G69231 thermo- autotrophicum 36069808_c1_79 3473 20044 1302 433 94 −1 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 35672905_c1_80 3474 20045 378 125 169 −12 Paracoccus AJ223460 (de:paracoccus denitrificans flhs, flhr, abca, denitrificans abcb, abcc, pqqe genesand orf's.) 16285208_c1_81 3475 20046 300 99 212 −17 Enterobacter cloacae CONTIG449 GTC ORF with score 212 to: (ai:7000768414) (or:Pseudomonas aeruginosa) 12932326_c1_83 3476 20047 216 71 110 −7 Klebsiella Contig486A GTC ORF with score 110 to: (ai:7000768416) pneumoniae (or:Pseudomonas aeruginosa) 12989206_c1_93 3477 20048 984 327 492 −47 Klebsiella Contig355A GTC ORF with score 492 to: (ai:7000768426) pneumoniae (or:Pseudomonas aeruginosa) 16989531 _c1_94 3478 20049 1083 360 671 −66 Xanthomonas Y11313 (de:x.campestris lpsi, lpsj, xana genes and campestris orfx.) 3151627_c2_96 3479 20050 741 246 157 −12 Klebsiella Contig536A GTC ORF with score 231 to: (ai:7000758601) pneumoniae (or:Pseudomonas aeruginosa) 22144591 _c2_98 3480 20051 819 272 409 −38 Pseudomonas P55172 (de:coenzyme pqq synthesis protein b) fluorescens 4488593_c2_99 3481 20052 762 253 1002 −101 Acinetobacter P07780 (de:coenzyme pqq synthesis protein c calcoaceticus (coenzyme pqq synthesis protein i)) 10667207_c2_101 3482 20053 1179 392 1448 −148 Klebsiella P27507 (de:coenzyme pqq synthesis protein e) pneumoniae 31532793_c2_102 3483 20054 1536 511 12147705_c2_104 3484 20055 216 71 110 −7 Klebsiella Contig507A GTC ORF with score 110 to: (ai:7000768437) pneumoniae (or:Pseudomonas aeruginosa) 34063330_c2_105 3485 20056 1722 573 477 −45 Paracoccus AJ223460 (de:paracoccus denitrificans flhs, flhr, abca, denitrificans abcb, abcc, pqqe genesand orf's.) 24667912_c2_116 3486 20057 1392 463 178 −13 Klebsiella Contig355A GTC ORF with score 178 to: (ai:7000768449) − pneumoniae (or:Pseudomonas aeruginosa) 14948277_c3_118 3487 20058 369 122 557 −54 Alteromonas sp. AB009654 (sr:alteromonas sp. (strain:ke10) dna) (de:alteromonas sp. dna for aldehyde dehydrogenase, complete cds.) 33612958_c3_119 3488 20059 429 142 117 −7 Pseudomonas S58242 fluorescens 13163505_c3_125 3489 20060 1845 614 926 −93 Cyanobactenum S75772 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 16033252_c3_126 3490 20061 495 164 132 −8 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 25518891_c3_127 3491 20062 1026 341 95 −I Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12630331_c3_128 3492 20063 1896 631 141 −6 Petromyzon marinus I51116 (sr:, sea lamprey) 25880216_c3_129 3493 20064 558 185 201 −16 Klebsiella Contig502A GTC ORF with score 201 to: (ai:7000768462) pneumoniae (or:Pseudomonas aeruginosa) 16042781_c3_131 3494 20065 2112 703 121 −4 Actinoplanes S16995 teichomyceticus 14649127_c3_132 3495 20066 807 268 790 −78 Bacillus P42315 (ec:2.8.3.5) (de:(ec 2.8.3.5) (succinyl coa:3- subtilis/Bacillus oxoacid coa-transferase) (oxct a)) globigii 3230216_c3_133 3496 20067 891 296 289 −26 Klebsiella Contig355A GTC ORF with score 289 to: (ai:7000768466) pneumoniae (or:Pseudomonas aeruginosa) 26257688_f2_3 3497 20068 381 127 440 −41 Pseudomonas P28812 (de:hypothetical protein in mmsb 3′region aeruginosa (orf1) (fragment)) 22783528_f3_4 3498 20069 330 109 530 −51 Pseudomonas P28811 (ec:1.1.1.31) (de:3-hydroxyisobutyrate aeruginosa dehydrogenase, (hibadh)) 2869567_f1_1 3499 20070 273 90 31925908_f1_2 3500 20071 852 283 132 −5 Homo sapiens Q07283 (sr:,human) (de:trichohyalin) 5182083_f2_5 3501 20072 594 198 95 −2 Schizo- Z95620 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c3d6.) (nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 16839693_f3_7 3502 20073 459 152 103 −4 Homo sapiens Q01130 (sr:,human) (de:protein) (splicing factor, arginine/serine-rich, 2)) 33728751_c1_9 3503 20074 732 243 295 −25 Cyanobacterium S77250 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 5867888_c3_12 3504 20075 978 326 123 −7 Klebsiella Contig520A GTC ORF with score 125 to: (ai:7000783750) pneumoniae (or:Pseudomonas aeruginosa) 13721091_f2_4 3505 20076 963 321 115 −3 Arabidopsis thaliana AL031032 (sr:thale cress) (de:arabidopsis thaliana dna chromosomc 4, bac clone f17i5 (essaiiproject).) (nt:strong similarity to extensin-like protein, zea) 20976412_f3_6 3506 20077 744 248 484 −46 Salmonella P40680 (de:protein erfk/srfk precursor) choleraesuis serotype typhimurium 2818818_c1_8 3507 20078 504 168 98 −3 Drosophila S49193 melanogaster 2469160_f3_6 3508 20079 1089 362 466 −44 Enterobacter cloacae CONTIG506 GTC ORF with score 803 to: (ai:7000778466) (or:Pseudomonas aeruginosa) 20175011_c1_9 3509 20080 1143 380 138 −9 Klebsiella Contig449A GTC ORF with score 138 to: (ai:7000768509) pneumoniae (or:Pseudomonas aeruginosa) 14974187_c2_11 3510 20081 1116 371 840 −84 Escherichia coli P08194 (de:permease)) 16878957_c3_12 3511 20082 255 84 14705181_f2_3 3512 20083 660 219 318 −29 Klebsiella Contig526A GTC ORF with score 615 to: (ai:7000844139) pneumoniae (or:Enterobacter cloacae) 4552081_f2_4 3513 20084 501 166 124 −7 Enterobacter cloacae CONTIG460 GTC ORF with score 1659 to: (ai :7501761809) (or: Klebsiella pneumoniae) 7245254_c2_11 3514 20085 216 71 2345458_c2_12 3515 20086 1125 375 253 −19 Pseudomonas putida P19176 (ec:2.7.7.6) (de:beta' chain) (rna polymerase beta' subunit)) 11798966_c3_13 3516 20087 1086 361 584 −57 Cyanobacterium S76771 (sr:pcc 6803,, pcc 6803) (sr:pcc 6803, ) synechocystis (ec:4.1.1.19) 6345168_f3_4 3517 20088 450 149 153 −10 Achromobacter D38633 (sr:pseudomonas sp. (strain:kks102) dna) georgiopolitanum (de:pseudomonas sp. bphr gene for regulatory protein, complete cds.) 26853275_f3_6 3518 20089 258 86 24229750_c1_7 3519 20090 360 119 104 −5 Rhizobium sp. P55411 (sr:ngr234,) (de:hypothetical 21.8 kd protein y4dl) 10364658_f1_2 3520 20091 336 111 171 −13 Klebsiella Contig556A GTC ORF with score 171 to: (ai:7000768539) pneumoniae (or:Pseudomonas aeruginosa) 23678811_f1_4 3521 20092 519 172 102 −4 Klebsiella Contig519A GTC ORF with score 102 to: (ai:7000768541) pneumoniae (or:Pseudomonas aeruginosa) 22930138_f1_7 3522 20093 495 164 134 −9 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 6456456_f1_22 3523 20094 2832 943 610 −59 Rhizobium Z70305 (fn:regulatory protein) (de:r.leguminosarum leguminosarum fix(k,l,n) and azu genes.) (nt:putative heme- binding, oxygen sensing protein) 31883253_f1_28 3524 20095 1227 408 319 −29 Acinciobacter CONTIG145 GTC ORF with score 382 to: (ai:7000803901) baumannii C (or:Pseudomonas aeruginosa) 26050962_f1_29 3525 20096 1833 610 249 −18 Pseudomonas X99514 (fn:outer membrane component of multidrug aeruginosa efflux) (de:p.aeruginosa mexe, mexf & oprn genes.) 12911643_f2_33 3526 20097 1836 611 577 −56 Escherichia coli JQ1475 (cl:methyl-accepting chemotaxis protein) 26054156_f2_34 3527 20098 2226 741 3579753_f2_36 3528 20099 468 155 99 −5 Klebsiella Contig446A GTC ORF with score 261 to: (ai:7000797825) pneumoniae (or:Pseudomonas aeruginosa) 35782001_f2_38 3529 20100 450 149 117 −6 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.). elegans (nt:similar to cuticular collagen; c18h7.3) 34494403_f2_51 3530 20101 432 143 93 −2 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt: cleavage of polyprotein at conserved spacers r or) 10020931_f2_55 3531 20102 1926 641 6851676_f2_58 3532 20103 846 281 345 −31 Mycobacterium AL022022 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 148/162.) (nt:rv3516, (mtv023.23), len: 263. echa19. probable) 12969842_f2_60 3533 20104 609 202 168 −12 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31677288_f2_61 3534 20105 297 98 26076_f2_62 3535 20106 1122 373 329 −30 Pseudomonas X99514 (fn:outer membrane component of multidrug aeruginosa efflux) (de:p. aeruginosa mexe, mexf & oprn genes.) 19635427_f3_71 3536 20107 2196 731 112 −5 Enterobacter cloacae CONTIG467 GTC ORF with score 129 to: (ai7000803168) (or:Pseudomonas aeruginosa) 25416013_f3_73 3537 20108 1119 372 93 −2 Homo sapiens AJ223093 (sr:human) (de:homo sapiens lage-1 gene.) 24487526_f3_78 3538 20109 339 112 36041457_f3_81 3539 20110 1002 333 124 −5 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, completecds.) 12679501_f3_82 3540 20111 1176 391 107 −3 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen; coded for by c. elegans) cdna) 13159828_f3_85 3541 20112 1074 357 97 −4 North American P35305 (sr:,north american opossum:short-tailed grey opossum opossum) (de:sperm protamine p1) 34507330_f3_88 3542 20113 1194 397 121 −4 Micrococcus luteus JQ0405 30707157_f3_90 3543 20114 435 144 100 −3 Chlamydomonas S50755 reinhardtii strain UTEX 1061 33723458_f3_91 3544 20115 900 300 137 −6 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pblueseriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 35819826_c1_94 3545 20116 1344 447 34485458_c1_103 3546 20117 432 143 97 −3 Indian corn JQ0985 (sr:, maize) 34504192_c1_104 3547 20118 834 277 166 −12 Klebsiella Contig405A GTC ORF with score 307 to: (ai:7000836103) pneumoniae (or:Enterobacter cloacae) 25832291_c1_105 3548 20119 1644 547 5151458_c1_114 3549 20120 1581 526 2244 −232 Pseudomonas Q03024 (de:alkaline protease secretion atp-binding aeruginosa protein aprd) 35644505_c1_115 3550 20120 1380 459 135 −6 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:knp i subfragment of orf24) 13179758_c1_116 3551 20122 1698 565 316 −42 Pseudomonas AF004848 (de:pseudomonas fluorescens alkaline fluorescens protease, protease inhibitor,zinc-protease transporter (aprd), zinc-protease transporter (apre),and zinc-protease transporter (aprf) genes,complete cds.) 7113165_c1_121 3552 20123 1173 390 165 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 24022062_c2_130 3553 20124 651 216 149 −10 Bacillus P42105 (de:hypothetical 21.0 kd protien in gntr-htpg subtilis/Bacillus intergenic region) globigii 16276927_c2_132 3554 20125 1443 480 134 −5 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 13025841_c2_134 3555 20126 483 160 182 −14 Enterobacter cloacae CONTIG482 GTC ORF with score 324 to: (ai:7501741983) (or:Klebsiella pneumoniae) 11187956_c2_141 3556 20127 1317 438 2087 −216 Pseudomonas AJ003006 (de:pseudomonas aeruginosa aprx and partial aeruginosa aprd genes.) (nt:hypothetical protein secreted by type i pathway) 10683165_c2_143 3557 20128 1947 648 2152 −223 Pseudomonas Q03025 (de:alkaline protease secretion protein apre) aeruginosa 4415956_c2_144 3558 20129 1449 482 2420 −251 Pseudomonas Q03027 (de:alkaline protease secretion protein aprf) aeruginosa 25438316_c2_147 3559 20130 411 136 109 −6 longfin squid S56117 (sr:, longfin squid) 32667706_c2_153 3560 20131 417 138 121 −8 Klebsiella Contig515A GTC ORF with score 121 to: (ai:7000768690) pneumoniae (or:Pseudomonas aeruginosa) 24820143_c2_155 3561 20132 1065 354 384 −35 Methanothermus P16142 (ec:1.1.1.37:1.1.1.82) (de:malate fervidus dehydrogenase,,) 675211_c3_157 3562 20133 1746 581 260957_c3_163 3563 20134 1830 609 94 −1 Bacillus U39230 (sr:bacillus sp) (de:bacillus sp. spra gene, partial cds and sprb, sprc, and sprd genes,complete cds.) (nt:alternative start site; subtilisin-like protease b) 33683458_c3_166 3564 20135 504 167 137 −8 Micrococcus luteus JQ0405 14947955_c3_175 3565 20136 1476 491 24851030_c3_177 3566 20137 321 106 95 −5 Klebsiella Contig415A GTC ORF with score 338 to: (ai:7000833436) pneumoniae (or:Enterobacter cloacae) 12602156_c3_180 3567 20138 480 159 487 −46 Pseudomonas AF004848 (de:pseudomonas fluorescens alkaline fluorescens protease, protease inhibitor,zinc-protease transporter (aprd), zinc-protease transporter (apre),and zinc-protease transporter (aprf) genes, complete cds.) 14876717_c3_183 3568 20139 1452 483 2479 −257 Pseudomonas Q03023 (ec:3.4.24.—) (de:alkaline metalloproteinase aeruginosa precursor, (ap)) 16610416_c3_184 3569 20140 642 213 677 −66 Pseudomonas Q03026 (de:proteinase inhibitor precursor) aeruginosa 35782276_c3_185 3570 20141 1683 560 171 −10 Enterobacter cloacae CONTIG479 GTC ORF with score 273 to: (ai:7000797020) (or:Pseudomonas aeruginosa) 4882801_f1_4 3571 20142 408 135 157 −11 Acinetobacter CONTIG231 GTC ORF with score 334 to: (ai:4000707890) baumannii C (or:Escherichia coli) (ec:4.2.1.17) (de:probable enoyl-coa hydratase paaf,) 24022062_c1_10 3572 20143 204 67 36070955_c3_16 3573 20144 579 192 131 −8 Cyanobacterium D64003 (sr:synechocystis sp. (strain:pcc6803) dna) synechocystis (de:synechocystis sp. pcc6803 complete genome, 22127, 2755703-2868766.) (nt:orf id:slr0895) 4408407_f2_4 3574 20145 1056 352 494 −46 Klebsiella Contig494A GTC ORF with score 2974 to: pneumoniae (ai:7000772743) (or:Pseudomonas aeruginosa) 14948767_c1_10 3575 20146 225 74 5371090_c3_15 3576 20147 1206 402 1284 −131 Pseudomonas putida P19175 (ec:2.7.7.6) (de:beta chain) (rna polymerase beta subunit)) 22859550_f3_4 3577 20148 1572 524 24080292_f1_2 3578 20149 213 70 26758263_c2_13 3579 20150 501 166 298 −26 Salmonella P14566 (ec:2.7.7.7) (de:dna polymerase iii, epsilon choleraesuis chain,) serotype typhimurium 26036580_c3_14 3580 20151 450 149 22754151_f1_1 3581 20152 255 84 130 −7 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 35822556_f2_5 3582 20153 639 212 790 −78 Azotobacter P54085 (de:(orf5)) chroococcum (strain mcd 1) 24120843_c1_11 3583 20154 417 138 197 −16 Klebsiella Contig534A GTC ORF with score 326 to: (ai:7000827719) pneumoniae (or:Enterobacter cloacae) 5120912_c1_12 3584 20155 630 210 102 −5 tammar wallaby P42138 (sr:,tammar wallaby) (de:sperm protamine p1) 961462_c3_15 3585 20156 831 276 137 −6 Homo sapiens P23327 (sr:,human) (de:precursor) 12985207_f1_7 3586 20157 435 144 131 −9 Aspergillus Contig5594 GTC ORF with score 225 to: (ai:5500691725) fumigatus (or:Santalum album) (sr:white sandalwood) (de:santalum album proline rich protein mrna, complete cds.) 33869581_f1_8 3587 20158 480 159 102 −3 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 22552328_f1_10 3588 20159 1755 584 833 −83 Pseudomonas D00852 (sr:pseudomonas fluorescens (strain:ifo3081) fluorescens dna) (de:pseudomonas fluorescens genes for esterase a and orf, complete andpartial cds.) (nt:orf similar to initiation factor 4a family) 30288267_f1_11 3589 20160 501 166 114 −4 Pseudomonas Z54213 (de:p.aeruginosa algy gene.) aeruginosa 5339080_f1_14 3590 20161 747 248 196 −15 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22789566_f1_17 3591 20162 1272 423 183 −14 Enterobacter cloacae CONTIG339 GTC ORF with score 306 to: (ai:7501729420) (or:Klebsiella pneumoniae) 25970905_f1_22 3592 20163 642 213 490 −47 Pseudomonas AF049486 (de:pseudomonas alcaligenes plasmid pra2 alcaligenes transposon tn5563 putative iontransport protein, mercuric ion transport protein homolog,transposase (tnpa), and resolvase (tnpr) genes. complete cds.) (nt:tnpr) 31816683_f1_23 3593 20164 1407 468 108 −3 mice|C57BL/6xCBA/ A26621 (cl:pol polyprotein) (sr:, house mouse) (ec:3.1.— Caj hybrid .—) 16488528_f1_26 3594 20165 1254 417 257 −22 Enterobacter cloacae CONTIG354 GTC ORF with score 883 to: (ai:7501774320) (or:Klebsiella pneumoniae) 33672091_f1_27 3595 20166 495 164 131 −7 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-carlygenes.) (nt:similar to hhv6a u86, region ie-b) 36428792_f1_29 3596 20167 462 153 131 −9 Klebsiella Contig506A GTC ORF with score 266 to: (ai:7000817989) pneumoniae (or:Enterobacter cloacae) 32526058_f1_30 3597 20168 1842 613 742 −74 Klebsiella Contig506A GTC ORF with score 917 to: (ai:7000817991) pneumoniae (or:Enterobacter cloacae) 11113152_f1_34 3598 20169 432 143 175 −14 Enterobacter cloacae CONTIG478 GTC ORF with score 175 to: (ai:7000768832) (or:Pseudomonas aeruginosa) 10260467_f1_36 3599 20170 345 114 212 −17 Enterobacter cloacae CONT1G477 GTC ORF with score 650 to: (ai:7501765953) (or:Klebsiella pneumoniae) 7301400_f1_37 3600 20171 1077 358 410 −38 Klebsiella Contig506A GTC ORF with score 474 to: (ai:7000834684) pneumoniae (or:Enterobacter cloacae) 13004055_f1_39 3601 20172 519 172 151 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11041308_f1_41 3602 21073 879 202 135 −6 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 34073900_f1_42 3603 20174 642 213 108 −4 Plasmodium P04922 (sr:nuri,) (de:circumsporozoite protein knowlesi precursor (cs)) 16541567_f1_43 3604 21075 558 185 192 −14 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35261531_f1_44 3605 20176 1098 365 115 −4 Homo sapiens PN0099 (sr:, man) 32602263_f1_45 3606 20177 672 223 12605015_f1_46 3607 20178 1689 562 169 −9 Bacillus P46351 (de:hypothetical 45.4 kd protien in thiaminase subtilis/Bacillus i 5′region) globigii 12269662_f1_50 3608 20179 2070 689 403 −37 Archaeoglobus F69372 fulgidus 31892580_f1_53 3609 20180 1383 460 160 −10 Enterobacter cloacae CONTIG454 GTC ORF with score 229 to: (ai:`7501747091) (or:Klebsiella pneumoniae) 14721090_f1_55 3610 20181 1605 534 4726640_f1_58 3611 20182 1026 341 140 −6 Homo sapiens P08123 (sr:,human) (de:procollagen alpha 2(i) chain precursor) 14317531_f1_60 3612 20183 375 124 98 −5 common tobacco PQ0475 (sr:, common tobacco) 16517933_f1_62 3613 20184 1029 342 198 −15 Photobacterium Q51872 (de:probable transcriptional regulator lumq) leiognathi 20111012_f1_63 3614 20185 1509 502 626 −61 Pseudomonas putida S46356 20586083_f1_64 3615 20186 3297 1098 229 −15 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 21660788_f1_65 3616 20187 1581 526 35742956_f1_67 3617 20188 717 238 108 −4 Drosophilia P50887 (sr:,fruit fly) (de:60s ribosomal protein 122) melanogaster 13179591_f1_68 3618 20189 1188 395 31880141_f1_72 3619 20190 411 136 119 −6 Streptomyces L20249 (sr:streptomyces coriofaciens (library: isp coriofaciens 5485) dna) (de:streptomyces coriofaciens beta- ketoacyl synthase homologue gene,partial cds.) (nt:homologous to saccharopolyspora erythraea) 24480168_f1_81 3620 20191 528 175 128 −7 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 35798333_f1_82 3621 20192 411 136 104 −6 Holothuria tubulosa P14309 (sr:,sea cucumber) (de:sperm-specific protein phi-0) 13019443_f1_83 3622 20193 1083 360 101 −2 mice|C57BL/6xCBA/ Q60925 (sr:,mouse) (de:d-binding protein (dbp) CaJ hybrid (albumin d box-binding protein)) 16902168_f1_86 3523 20194 1710 569 114 −4 Klebsiella Contig489A GTC ORF with score 974 to: (ai:7000820328) pneumoniae (or:Enterobacter cloacae) 22526907_f1_87 3624 21095 1092 363 145 −6 mice|C57BL/6xCBA/ Q01149 (sr:,mouse) (de:procollagen alpha 2(i) chain CaJ hybrid precursor) 35676681_f1_91 3625 20196 1650 549 98 −1 Homo sapiens U80742 (sr:human) (de:homo sapiens cagh45 mrna, complete cds.) (nt:glutamine rich) 31536706_f1_98 3626 21097 1887 628 241 −18 Klebsiella Contig508A GTC ORF with score 241 to: (ai:7000768896) pneumoniae (or:Pseudomonas aeruginosa) 14166387_f1_99 3627 20198 1239 412 16300283_f1_100 3628 20199 1287 428 103 −2 Drosophila hydei Y14994 (de:drosophila hydei mrna for lola-like protein.) 32682707_f1_106 3629 20200 816 271 565 −55 Helicobacter pylori D64715 6354531_f1_107 3630 20201 1149 382 522 −50 Escherichia coli P77743 (de:propionate catabolism operon regulatory protein) 26461443_f1_108 3631 20202 2037 678 1581 −162 Escherichia coli P17447 (de:high-affinity choline transport protein) 24690812_f1_114 3632 20203 1062 353 179 −13 Enterobacter cloacae CONTIG468 GTC ORF with score 179 to: (ai:7000768912) (or:Pseudomonas aeruginosa) 29900958_f1_117 3633 20204 1071 356 229 −19 Klebsiella Contig520A GTC ORF with score 472 to: (ai:7000832967) pneumoniae (or:Enterobacter cloacae) 4416455_f1_122 3634 20205 525 174 108 −4 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 16992706_f1_126 3635 20206 519 172 96 −3 Klebsiella Contig306A GTC ORF with score 179 to: (ai:7000810282) pneumoniae (or:Pseudomonas aeruginosa) 15862962_f1_132 3636 20207 1491 496 35660416_f1_146 3637 20208 540 179 118 −5 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 12579055_f2_148 3638 20209 1314 437 228 −17 Methanobacterium C69066 thermo- autotrophicum 15830205_f2_149 3639 20210 1845 614 187 −13 Escherichia coli P45533 (de:hypothetical 27.4 kd protein in rpsl-fkpa intergenic region (f244)) 4812716_f2_151 3640 20211 324 107 91 −4 Pseudomonas putida AF052751 (de:pseudomonas putida plasmid ppgh 1 insertion sequence is 1384transposase (tnpa) gene, complete cds.) 26587661_f2_160 3641 20212 426 141 31487830_f2_164 3642 20213 855 284 202 −14 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- Cad hybrid prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 29969433_f2_166 3643 20214 828 275 249 −21 Enterobacter cloacae CONTIG328 GTC ORF with score 574 to: (ai:7501765980) (or:Klebsiella pneumoniae) 5104712_f2_175 3644 20215 198 65 176 −14 Enterobacter cloacae CONTIG477 GTC ORF with score 651 to: (ai:7501765954) (or:Klebsiella pneumoniae) 24864836_f2_179 3645 20216 939 312 196 −12 Mycobacterium AF034152 (de:mycobacterium smegmatis exochelin gene smegmatis cluster, exit (exit) and fxbb (fxbb) genes, complete cds; and fxbc (fxbc) gene, partial cds.) (nt:abc transporter; this abc transporter probably) 16666451_f2_180 3646 20217 699 232 133 −7 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome;segment 123/162.) (nt:rv2839c, (mtcy16b7.03), len: 900. probable infb,) 30085216_f2_181 3647 20218 810 269 1069 −108 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 35807283_f2_182 3648 20219 480 159 10253513_f2_183 3649 20220 1311 436 104 −3 Bos primigenius P42916 (sr:,bovine) (de:collectin-43 (cl-43)) taurus 2363533_f2_184 3650 20221 870 289 324 −29 Helicobacter pylori U94318 (de:helicobacter pylori vapd (vapd), vdld (vdld), vdlc (ydlc), hemu(hemu) and fepc (fepc) genes, complete cds.) 23848793_f2_185 3651 20222 744 247 211 −17 Acinetobacter CONTIG133 GTC ORF with score 211 to: (ai:7000768983) baumannii C (or:Pseudomonas aeruginosa) 4322806_f2_191 3652 20223 753 250 353 −32 Bacillus H69669 subtilis/Bacillus globigii 34104092_f2_193 3653 20224 1548 515 147 −7 Achromobacter A61183 georgiopolitanum 36121056_f2_195 3654 20225 636 211 119 −6 Klebsiella Contig305A GTC ORF with score 159 to: (ai:7000760621) pneumoniae (or:Pseudomonas aeruginosa) 35286418_f2_199 3655 20226 306 101 97 −4 mice|C57BL/6xCBA/ U72519 (sr:house mouse) (de:mus musculus ena-vasp Caj hybrid like protein (evl) mrna, complete cds.) (nt:cytoskelatal protein; neural-specific; ena/vasp) 1035463_f2_202 3656 20227 966 321 450 −42 Cyanobacterium S77111 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 35286418_f2_205 3657 20228 1539 512 323 −29 Enterobacter cloacae CONTIG98 GTC ORF with score 568 to: (ai:7501770497) (or:Klebsiella pneumoniae) 10393780_f2_207 3658 20229 534 177 461 −44 Pseudomonas putida S46355 32151057_f2_209 3659 20230 600 199 144 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 24886586_f2_210 3660 20231 2274 757 2463 −256 Escherichia coli P13036 (de:iron(iii) dicitrate transport protein feca precursor) 52030_f2_211 3661 20232 1644 547 1920 −198 Haemophilus P43928 (de:peptide chain release factor 3 (rf-3)) influenzae 12292641 _f2_213 3662 20233 705 234 31883507_f2_214 3663 20234 1158 385 168 −12 Ovis orientalis aries U77049 (sr:sheep) (de:ovis aries bactinecin 11 (bac11) gene, exon 4, and complete cds.) 10235417_f2_215 3664 20235 447 148 90 −5 Klebsiella Contig529A GTC ORF with score 93 to: (ai:7000831450) pneumoniae (or:Enterobacter cloacae) 17035965_f2_216 3665 20236 1230 409 25442883_f2_217 3666 20237 4167 1388 141 −6 Pleuronectes U39735 (de:pleuronectes americanus sperm chromatin americanus protein hmrbnp-1 mrna,partial cds.) (nt:hmrbnp-1; crosslinks nucleosomes in sperm) 16930141_f2_220 3667 20238 669 222 405 −38 Klebsiella Contig548A GTC ORF with score 671 to: (ai:7000827050) pneumoniae (or:Enterobacter cloacae) 22947911_f2_221 3668 20239 501 166 256 −22 Enterobacter cloacae CONTIG433 GTC ORF with score 671 to: (ai:7501788447) (or:Klebsiella pneumoniae) 11848562_f2_222 3669 20240 1656 551 193 −15 Klebsiella Contig537A GTC ORF with score 423 to: (ai:7000831855) pneumoniae (or:Enterobacter cloacae) 2366332_f2_223 3670 20241 474 157 207 −17 Klebsiella Contig525A GTC ORF with score 241 to: (ai:7000819514) pneumoniae (or:Enterobacter cloacae) 34276966_f2_224 3671 20242 807 268 305 −27 Klebsiella Contig525A GTC ORF with score 305 to: (ai:7000769022) pneumoniae (or:Pseudomonas aeruginosa) 23876661_f2_228 3672 20243 945 314 519 −49 Bacillus E70041 (cl:enterococcus cu2+−transporting subtilis/Bacillus atpase:atpase nucleotide-binding domain globigii homology:atpase transduction domain homology) 13016033_f2_229 3673 20244 450 149 94 −2 Caenorhabditis U79157 (de:caenorhabditis elegans splicing factor elegans u2af65 mrna, complete cds.) 35830166_f2_230 3674 20245 1110 369 174 −10 Araneus diadematus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, partial cds.) 10425333_f2_231 3675 20246 459 152 136 −8 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 34190780_f2_242 3676 20247 747 248 158 −12 Aspergillus Contig9833 GTC ORF with score 158 to: (ai:7000769040) fumigatus (or:Pseudomonas aeruginosa) 10972516_f2_244 3677 20248 1182 393 1945 −201 Pseudomonas U88653 (de:pseudomonas aeruginosa thiolase (phaa) aeruginosa gene, complete cds.) 32083526_f2_250 3678 20249 2742 913 131 −4 no gb taxonomy U93872 (sr:kaposi's sarcoma-associated herpesvirus - match human herpesvirus 8) (de:kaposi's sarcoma- associated herpesvirus glycoprotein m, dnareplication protein, glycoprotein, dna replication protein, fliceinhibitory protein and v-cvclin genes. . . 12755305_f2_252 3679 20250 324 107 105 −4 Rattus norvegicus A54895 (sr:, norway rat) 34510955_f2_254 3680 20251 240 79 93 −4 mice|C57BL/6xCBA/ P54728 (sr:,mouse) (de:repair complementing complex CaJ hybrid 58 kd protein) (p58)) 32682340_f2_258 3681 20252 504 167 156 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12610465_f2_260 3682 20253 624 207 99 −2 infectious bovine L14321 (sr:bovine herpesvirus type 1 (strain jura rhinotracheitis virus (subtype 1.1)) dna) (de:bovine herpesvirus type 1 immediate-early transcriptional controlprotein (bicp4) gene, 5′ end.) (nt:strain jura sequence encoding n-terminal half of) 3176033_f2_264 3683 20254 1122 373 104 −1 Homo sapiens AF010404 (sr:human) (de:homo sapiens alr mrna, complete cds.) (nt:alternatively spliced; similarity to all-1 and) 5129081_f2_271 3684 20255 672 223 96 −2 Pseudomonas S29309 aeruginosa 14557305_f2_276 3685 20256 1311 436 114 −3 Homo sapiens U75308 (sr:human) (de:human tbp-associated factor (htafii130) mrna, partial cds.) (nt:the c- terminal region is similar to drosophila) 31775833_f2_278 3686 20257 429 142 108 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 36134706_f2_282 3687 20258 1797 598 36454776_f2_283 3688 20259 1857 618 10677186_f3_296 3689 20260 777 258 705 −69 Pseudomonas Q51758 (ec:3.1.1.1) (de:carboxylesterase 1, (esterase fluorescens i)) 3338291_f3_297 3690 20261 2181 726 192 −12 Klebsiella Contig452A GTC ORF with score 975 to: (ai:7000824092) pneumoniae (or:Enterobacter cloacae) 11745756_f3_300 3691 20262 1281 426 116 −4 Klebsiella Contig558A GTC ORF with score 411 to: (ai:7000841160) pneumoniae (or:Enterobacter cloacae) 14558156_f3_302 3692 20263 1191 396 5891908_f3_307 3693 20264 264 87 34275630_f3_321 3694 20265 1869 622 270 −23 Klebsiella Contig478A GTC ORF with score 271 to: (ai:7000835176) pneumoniae (or:Enterobacter cloacae) 30739705_f3_326 3695 20266 4506 1501 1676 −173 Klebsiella Contig506A GTC ORF with score 1676 to: pneumoniae (ai:7000769124) (or:Pseudomonas aeruginosa) 10235841_f3_329 3696 20267 1296 431 119 −4 malaria parasite A25942 1954212_f3_330 3697 20268 1881 626 3130 −9999 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 16933291_f3_333 3698 20269 666 221 26777206_f3_334 3699 20270 765 254 266 −23 white spruce LA7672 (sr:picea glauca mature somatic embryo cdna to mrna) (de:picea glauca embryo-abundant protein (emb34) mrna, complete cds.) (nt:embryo-abundant protein) 11035908_f3_335 3700 20271 333 110 128 −8 Chlamydomonas S50754 eugametos 9895942_f3_337 3701 20272 690 229 115 −3 Epstein-Barr virus P03186 (sr:b95-8,human herpesvirus 4) (de:large tegument protein) 34110290_f3_338 3702 20273 468 155 99 −3 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26600431_f3_344 3703 20274 669 222 441 −41 Bacillus D69670 subtilis/Bacillus globigii 24714211_f3_345 3704 20275 1176 391 826 −82 Bacillus C69670 (cl:atp-binding cassette homology) subtilis/Bacillus globiitii 10814557_f3_351 3705 20276 1629 542 119 −5 Klebsiella Contig558A GTC ORF with score 282 to: (ai:7000758048) pneumoniae (or:Pseudomonas aeruginosa) 10730331_f3_353 3706 20277 1338 445 714 −70 Escherichia coli P37666 (de:putative 2-hydroxyacid dehydrogenase in bisc-cspa intergenic region) 865676_f3_356 3707 20278 489 162 114 −4 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 15880432_f3_357 3708 20279 819 272 178 −11 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 13783406_f3_360 3709 20280 537 178 222 −17 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) (de:glucosidase) cerevisiae (1,4-alpha-d-glucan glucohydrolase)) 5250433_f3_368 3710 20281 468 155 29942715_f3_370 3711 20282 468 155 16284836_f3_384 3712 20283 480 159 196 −16 Enterobacter cloacae CONTIG433 GTC ORF with score 196 to: (ai:7000769182) (or:Pseudomonas aeruginosa) 34071081_f3_386 3713 20284 612 203 107 −3 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 16895652_f3_387 3714 20285 423 140 195 −16 Klebsiella Contig537A GTC ORF with score 195 to: (ai:7000769185) pneumoniae (or:Pseudomonas aeruginosa) 16050706_f3_388 3715 20286 363 120 99 −4 Saccharomyces S66852 (mp:151) cerevisiae 16878780_f3_398 3716 20287 1593 530 1219 −124 Mycobacterium P77894 (ec:3.6.1.—) (de:probable cation-transporting tuberculosis atpase cy10d7.05c,) 12360183_f3_399 3717 20288 495 164 141 −10 Pseudomonas S29309 aeruginosa 16250905_f3_400 3718 20289 741 246 225 −18 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 15664818_f3_402 3719 20290 567 188 125 −6 Rhesus Epstein Barr U93909 (sr:rhesus epstein barr virus) virus (de:cercopithecine herpesvirus 15 nuclear antigen cbna-1 gene, completecds.) 255188_f3_404 3720 20291 3417 1138 29791555_f3_406 3721 20292 417 138 135 −8 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 25574156_f3_407 3722 20293 849 282 386 −36 Escherichia coli P76241 (de:hypothetical transcriptional regulator in gapa-rnd intergenic region) 33635333_f3_410 3723 20294 261 86 205 −17 Klebsiella Contig517A GTC ORF with score 205 to: (ai:7000769208) pneumoniae (or:Pseudomonas aeruginosa) 36504032_f3_412 3724 20295 630 209 331 −30 Klebsiella Contig517A GTC ORF with score 331 to: (ai:7000769210) pneumoniae (or:Pseudomonas aeruginosa) 35312510_f3_415 3725 20296 789 262 94 −2 Canis familiaris P43698 (sr:,dog) (de:thyroid transcription factor 1 (thyroid nuclear factor 1) (ttf-1)) 35260391_f3_417 3726 20297 642 213 94 −3 Klebsiella Contig550A GTC ORF with score 134 to: (ai:6000693762) pneumoniae (or:Nicotiana alata) (sr:persian tobacco) (de:nicotiana alata 120 kda style glycoprotein (naprp5) mrna, completecds.) (nt:style-specific protein possessing features of) 16054041_f3_418 3727 20298 1908 635 248 −20 Klebsiella Contig442A GTC ORF with score 248 to: (ai:7000769216) pneumoniae (or:Pseudomonas aeruginosa) 4980206_f3_419 3728 20299 1833 610 35682828_f3_422 3729 20300 291 96 252 −22 Enterobacter cloacae CONTIG468 GTC ORF with score 638 to: (ai:7501771824) (or:Klebsiella pneumoniae) 22113181_f3_423 3730 20301 960 319 344 −31 Klebsiella Contig520A GTC ORF with score 344 to: (ai:7000769221) pneumoniae (or:Pseudomonas aeruginosa) 16290875_f3_426 3731 20302 1026 341 190 −12 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 35598818_f3_427 3732 20303 477 158 200 −16 Bacillus P08821 (de:dna-binding protein ii (hb) (hu)) subtilis/Bacillus globigii 12792036_f3_430 3733 20304 498 165 110 −4 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 3914152_f3_446 3734 20305 654 218 592 −57 Bordetella pertussis P16574 (de:virulence factors putative positive transcription regulator bvga) 33773468_c1_447 3735 20306 1233 410 512 −49 Vibrio cholerae AF031552 (de:vibrio cholerae magnesium transporter (mgte) gene, partial cds;sensor kinase (vies), response regulator (viea), and response regulator (vieb) genes, complete cds; and collagenase (vcc) gene,partial cds) 34612530_c1_453 3736 20307 627 208 387 −36 Proteus mirabilis AJ000084 (de:proteus mirabilis ccm and pat genes and partial ygba gene.) 35238392_c1_457 3737 20308 312 103 93 −3 Sus scrofa domestica I47141 (sr:, domestic pig) 6522905_c1_458 3738 20309 414 137 102 −5 Human Q80910 (de:regulatory protein e2) papillomavirus type 38 11899183_c1_460 3739 20310 1005 334 233 −18 Pseudomonas AF026067 (de:pseudomonas aeruginosa putative aeruginosa reductase (slfa), putativefmnh2-dependent monooxygenase (slfb), and putative fmnh2- dependentmonooxygenase (slfc) genes, complete cds.) 22741630_c1_461 3740 20311 1116 371 894 −89 Escherichia coli Q47537 (de:induced protein 1) (ssi1)) 2994502_c1_462 3741 20312 780 259 149 −7 Micrococcus luteus JQ0405 31305155_c1_463 3742 20313 357 118 104 −6 mice|C57BL/6xCBA/ A37199 (sr:, house mouse) CaJ hybrid 34411036_c1_464 3743 20314 840 279 884 −88 Escherichia coli P37610 (ec:1.—.—.—) (de:starvation-induced protein 3) (ssi3)) 7292508_c1_465 3744 20315 537 178 512 −49 Mycobacterium Z81368 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome segment 106/162) (nt:rv2395, (mtcy253.26c), len: 667: probable membrane) 22474181_c1_467 3745 20316 1176 391 152 −7 Homo sapiens X15332 (sr:human) (de:human col3a1 mrna for pro alpha-1 (iii) collagen.) 32595461_c1_469 3746 20317 1515 504 427 −40 Enterobacter cloacae CONTIG459 GTC ORF with score 533 to: (ai:7501748159) (or:Klebsiella pneumoniae) 21536555_c1_470 3747 20318 543 180 98 −3 Klebsiella Contig535A GTC ORF with score 636 to: (ai:7000826275) pneumoniae (or:Enterobacter cloacae) 35828276_c1_472 3748 20319 996 331 220 −18 Klebsiella Contig357A GTC ORF with score 397 to: (ai:7000813860) pneumoniae (or:Enterobacter cloacae) 5213417_c1_477 3749 20320 207 68 11958256_c1_481 3750 20321 1269 422 179 −11 Streptomyces P42670 (sr:,streptomyces alboniger) (de:puromycin anulatus resistance protein pur8) 30574080_c1_483 3751 20322 465 154 175 −14 Klebsiella Contig560A GTC ORF with score 106 to: (ai:1500692508) pneumoniae (or:Boreogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26572918_c1_484 3752 20323 474 157 230 −19 Klebsiella Contig355A GTC ORF with score 250 to: (ai:7000795354) pneumoniae (or:Pseudomonas aeruginosa) 16120307_c1_485 3753 20324 1752 583 1525 −156 Archaeoglobus H69503 fulgidus 11724216_c1_486 3754 20325 225 74 25508256_c1_488 3755 20326 1218 405 32635130_c1_493 3756 20327 2766 921 566 −51 Mycobacterium Z83866 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 133/162.) (nt:rv3080c, (mtv013.01c-mtcy22d7.01),: 1110.) 26595830_c1_498 3757 20328 1398 465 671 −66 Bacillus A69873 subtilis/Bacillus globigii 32550817_c1_500 3758 20329 762 253 491 −47 Escherichia coli S34999 (mp:18 min) 13001006_c1_507 3759 20330 672 223 294 −26 Escherichia coli P45474 (de:hypothetical 19.7 kd protein in soha-mtr intergenic region (f174)) 29819833_c1_512 3760 20331 426 141 133 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33807291_c1_519 3761 20332 672 223 136 −6 Acanthamoeba P19706 (sr:,amoeba) (de:myosin heavy chain ib castellanii (myosin heavy chain il)) 26597328_c1_527 3762 20333 690 229 26302058_c1_540 3763 20334 3270 1089 636 −61 Burkholderia P24128 (sr:,pseudomonas cepacia) (de:fusaric acid cepacia resistance protein fusc) 13129706_c1_543 3764 20335 240 79 117 −7 Escherichia coli P46478 (de:hypothetical 10.3 kd protein in argr-cafa intergenic region (f90)) 16283543_c1_544 3765 20336 945 314 588 −57 Escherichia coli P76185 (de:hypothetical 33.0 kd protein in slya-sodc intergenic region) 877192_c1_546 3766 20337 927 308 177 −13 Enterobacter cloacae CONTIG513 GTC ORF with score 177 to: (ai:7000769344) (or:Pseudomonas aeruginosa) 36349206_c1_550 3767 20338 1545 514 2103 −218 Pseudomonas AB010827 (sr:pseudomonas aeruginosa (str:pao1) dna) aeruginosa (de:pseudomonas aeruginosa gene for nhap, complete cds.) 35354167_c1_558 3768 20339 522 173 115 −4 no gb taxonomy AB011489 (sr:tt virus (iso1:g104901 specific_h:homo match sapiens) dna) (de:tt virus dna for short and long orf, partial and complete cds,isolate g104901.) (nt:long orf) 25518883_c1_568 3769 20340 2784 927 1497 −153 Pseudomonas Y15252 (fn:nitrate transporter) (de:pseudomonas aeruginosa aeruginosa narx, narl, nark1, nark2, narg, narh, narj,nari, nifm, moaa genes.) 26345443_c1_569 3770 20341 1251 416 173 −13 Klebsiella Contig478A GTC ORF with score 173 to: (ai:7000769367) pneumoniae (or:Pseudomonas aeruginosa) 36148576_c1_573 3771 20342 795 264 132 −7 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 31540816_c1_574 3772 20343 1923 640 2768 −288 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 15726030_c1_575 3773 20344 510 169 98 −2 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 35282067_c1_577 3774 20345 1785 594 937 −94 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 2767566_c1_586 3775 20346 897 298 888 −89 Pseudomonas AF012537 (de:pseudomonas aeruginosa acetyl-coa aeruginosa synthetase gene, partial cds; andarginine and ornithine binding protein (aotj), membrane protein(aotq), membrane protein (aotm), aoto (aoto), atpasc (aotp), andargr (argr) genes, complete cds ) ( . . . 16932331_c1_593 3776 20347 1602 533 390 −36 Klebsiella Contig525A GTC ORF with score 1123 to: pneumoniae (ai:7000829218) (or:Enterobacter cloacae) 33724207_c1_594 3777 20348 2082 693 128 −5 Plasmodium P04922 (sr:nuri,) (de:circumsporozoite protein knowlesi precursor (cs)) 13010941_c1_595 3778 20349 417 138 121 −6 Homo sapiens X15332 (sr:human) (de:human col3a1 mrna for pro alpha-1 (iii) collagen.) 16972091_c1_596 3779 20350 1320 439 1076 −109 Escherichia coli P45766 (de:intergenic region precursor) 16225961_c1_597 3780 20351 783 260 347 −31 Lyme disease A70131 (sr:, lyme disease spirochete) spirochete 29552316_c2_603 3781 20352 1515 504 92 −1 Ralstonia eutropha AF026544 (de:ralstonia eutropha beta-ketothiolase (bktb) gene, complete cds; andunknown genes.) (nt:orf3; similar to e. coli f441 predicted product) 15119791_c2_607 3782 20353 2112 703 526 −50 Aquifex acolicus H70379 22157653_c2_608 3783 20354 516 171 102 −6 Aspergillus Contig4845 GTC ORF with score 102 to: (ai:7000769406) fumigatus (or:Pseudomonas aeruginosa) 6540818_c2_610 3784 20355 606 201 223 −18 Archaeoglobus H69365 fulgidus 5182331_c2_617 3785 20356 1089 362 699 −69 Escherichia coli Q47538 (de:taurine transport atp-binding protein taub) 15094535_c2_618 3786 20357 918 305 114 −3 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 33839465_c2_622 3787 20358 1656 551 1274 −130 Haemophilus P44016 (de:hypothetical protein hi0561/560) influenzae 30472962_c2_624 3788 20359 294 97 127 −8 Acinetobacter CONTIG231 GTC ORF with score 127 to: (ai:7000769422) baumannii C (or:Pseudomonas aeruginosa) 24650832_c2_629 3789 20360 351 116 144 −10 Klebsiella Contig350A GTC ORF with score 467 to: (ai:7000822795) pneumoniae (or:Enterobacter cloacae) 10426581_c2_630 3790 20361 414 137 100 −5 Klebsiella Contig531A GTC ORF with score 682 to: (ai:70008426S7) pneumoniae (or:Enterobacter cloacae) 17071033_c2_634 3791 20362 1182 393 117 −4 Caenorhabditis Z81479 (de:caenorhabditis elegans cosmid c34f6, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 26432218_c2_635 3792 20363 1290 429 314 −28 Klebsiella Contig469A GTC ORF with score 314 to: (ai:7000769433) pneumoniae (or:Pseudomonas aeruginosa) 10041682_c2_640 3793 20364 507 168 120 −8 Aspergiilus Contig8078 GTC ORF with score 219 to: (ai:175260) fumigatus (or:Volvox carteri) 34629162_c2_643 3794 20365 2115 704 699 −79 Pseudomonas U10470 (de:pseudomonas fluorescens pha fluorescens depolymerase (phaz) gene, complete cds.) (nt:orf1; gtg start codon translated as val) 16900890_c2_644 3795 20366 1428 475 1382 −141 Pseudomonas U10470 (de:pseudomonas fluorescens pha fluorescens depolymerase (phaz) gene, complete cds.) 33880330_c2_647 3796 20367 459 152 112 −5 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 13004192_c2_650 3797 20368 1800 599 215 −17 Enterobacter cloacae CONTIG362 GTC ORF with score 358 to: (ai:7501759418) (or:Klebsiella pneumoniae) 14925681_c2_654 3798 20369 402 133 128 −7 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) (de:glucosidase) cerevisiae (1,4-alpha-d-glucan glucohydrolase)) 31926417_c2_656 3799 20370 657 218 173 −13 Escherichia coli P30748 (de:subunit)) 22128942_c2_659 3800 20371 1119 372 131 −5 Bos primigenius P04258 (sr:,bovine) (de:collagen alpha 1(iii) chain) taurus 35674156_c2_662 3801 20372 441 146 161 −12 Enterobacter cloacae CONTIG433 GTC ORF with score 261 to: (ai:7501788573) (or:Klebsiella pneumoniae) 16147891_c2_663 3802 20373 990 329 706 −69 Escherichia coli P45475 (de:hypothetical 33.2 kd protein in soha-mtr intergenic region (o298)) 32593891_c2_667 3803 20374 795 264 124 −5 Caenorhabditis Z68011 (de:caenorhabditis elegans cosmid t21b6, elegans complete sequence.) (nt:similarity to xenopus f- spondin precursor (pir acc.) 15723916_c2_670 3804 20375 1953 650 210 −14 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 16603291_c2_675 3805 20376 1302 433 147 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34611537_c2_680 3806 20377 675 224 114 −4 minor jackknife L41834 (sr:ensis minor(clone:1/6) male adult gonads clam cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 10199081_c2_687 3807 20378 2334 777 295 −25 Klebsiella Contig463A GTC ORF with score 438 to: (ai:7000821248) pneumoniae (or:Enterobacter cloacae) 10552158_c2_689 3808 20379 1647 548 818 −81 Burkholderia P24126 (sr:,pseudomonas cepacia) (de:fusaric acid cepacia resistance protein fusa) 10005030_c2_692 3809 20380 1020 339 98 −2 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 31913205_c2_693 3810 20381 2253 750 694 −69 Enterobacter cloacae CONTIG513 GTC ORF with score 694 to: (ai:7000769491) (or:Pseudomonas aeruginosa) 34557330_c2_703 3811 20382 513 170 90 −3 Anthonomus grandis P17502 (sr:,boll weevil) (de:protamine) 11736393_c2_709 3812 20383 1998 665 243 −20 Enterobacter cloacae CONTIG477 GTC ORF with score 359 to: (ai:7501766081) (or:Klebsiella pneumoniae) 24303275_c2_710 3813 20384 1368 455 2248 −233 Pseudomonas Y15252 (fn:nitrate transporter) (de:pseudomonas aeruginosa aeruginosa narx, narl, nark1, nark2, narg, narh, narj,nari, nifm, moaa genes.) 29969765_c2_711 3814 20385 627 208 971 −98 Pseudomonas Y15252 (fn:nitrate transporter) (de:pseudomonas aeruginosa aeruginosa narx, narl, nark1, nark2, narg, narh, nari,nari, nifm, moaa genes.) 16205016_c2_712 3815 20386 3825 1274 6831 −9999 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 24338157_c2_713 3816 20387 495 164 154 −10 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerivisiae subunit precursor) 30558405_c2_716 3817 20388 1458 485 1148 −116 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 34409705_c2_717 3818 20389 825 274 1279 −130 Pseudomonas Y15252 (fn:required for activation and stabilization of) aeruginosa (de:pseudomonas aeruginosa narx, narl, nark1, nark2, narg, narh, narj,nari, nifm, moaa genes.) 13026592_c2_732 3819 20390 480 159 158 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10395682_c2_739 3820 20391 468 155 176 −14 Enterobacter cloacae CONTIG307 GTC ORF with score 733 to: (ai:7501734596) (or:Klebsiella pneumoniae) 35754793_c2_741 3821 20392 1986 661 679 −67 Archaeoglobus C69471 fulgidus 34647630_c2_745 3822 20393 294 97 109 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33863205_c2_747 3823 20394 699 232 16484408_c3_750 3824 20395 4884 1627 2171 −225 Bordetella P40330 (ec:2.7.3.—) (de:virulence sensor protein bvgs parapertussis precursor,) 31421905_c3_752 3825 20396 945 314 390 −36 Proteus mirabilis AJ000084 (de:proteus mirabilis ccm and pat genes and partial ygba gene.) 12354181_c3_754 3826 20397 1092 363 487 −46 Arabidopsis thaliana U89959 (sr:thale cress) (de:arabidopsis thaliana bac t7i23, complete sequence.) (nt:hypothetical protein) 33800406_c3_755 3827 20398 903 300 804 −80 Escherichia coli D64775 (ec:3.1.2.—) 14978840_c3_757 3828 20399 567 188 125 −8 Klebsiella Contig444A GTC ORF with score 264 to: (ai:7000803947) pneumoniae (or:Pseudomonas aeruginosa) 31275066_c3_760 3829 20400 603 200 156 −10 Araneus diadematus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, partial cds.) 12361387_c3_762 3830 20401 411 136 96 −4 Enterobacter cloacae CONTIG512 GTC ORF with score 96 to: (ai:7000769560) (or:Pseudomonas aeruginosa) 31775965_c3_764 3831 20402 978 325 728 −72 Escherichia coli G64764 (cl:hypothetical protein b0934) 15680442_c3_776 3832 20403 1479 492 2554 −265 Pseudomonas Y10528 (de:p.aeruginosa cioa and ciob genes.) aeruginosa 4197163_c3_777 3833 20404 1011 336 1765 −182 Pseudomonas Y10528 (de:p.aeruginosa cioa and ciob genes.) aeruginosa 32511581_c3_779 3834 20405 570 189 160 −12 Klebsiella Contig511A GTC ORF with score 187 to: (ai:7000777179) pneumoniae (or:Pseudomonas aeruginosa) 31542631_c3_781 3835 20406 2034 677 311 −27 Klebsiella Contig355A GTC ORF with score 521 to: (ai:7000795297) pneumoniae (or:Pseudomonas aeruginosa) 12517637_c3_782 3836 20407 1743 580 142 −8 Candida albicans b9x12t47.y GTC ORF with score 142 to: (ai:7000769580) (or:Pseudomonas aeruginosa) 22784501_c3_789 3837 20408 2874 957 353 −28 mice|C57BL/6xCBA/ A41182 (cl:collagen alpha 1(i) chain:fibrillar collagen CaJ hybrid carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, house mouse) 26036403_c3_790 3838 20409 1833 610 254 −18 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 1292681_c3_793 3839 20410 1389 462 4822956_c3_794 3840 20411 726 241 513 −49 Haemophilus P45310 (de:molybdenum cofactor biosynthesis protein influenzae c) 16276015_c3_795 3841 20412 549 182 416 −39 Escherichia coli P30749 (de:subunit)) 26272011_c3_796 3842 20413 1617 538 670 −66 Escherichia coli P12281 (de:molybdopterin biosynthesis moca protein) 25406418_c3_797 3843 20414 1110 369 1154 −117 Escherichia coli P45527 (ec:3.4.—.—) (de:(cc 3.4.—.—)) 21722666_c3_801 3844 20415 1623 540 12142842_c3_802 3845 20416 2355 784 719 −117 Cyanobacterium S74915 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) syncchocystis 32620655_c3_805 3846 20417 504 167 100 −2 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 2345467_c3_807 3847 20418 1896 631 531 −51 Klebsiella Contig346A GTC ORF with score 531 to: (ai:7000769605) pneumoniae (or:Pseudomonas aeruginosa) 5988576_c3_810 3848 20419 1245 414 12551041_c3_811 3849 20420 438 145 102 −4 Caenorhabditis Z66521 (de:caenorhabditis elegans cosmid w02b12, elegans complete sequence.) (nt:similar to pre-mrna splicing factor like protein;) 26354187_c3_817 3850 20421 978 325 167 −10 Bacillus F70030 subtilis/Bacillus globigii 15050956_c3_821 3851 20422 1350 449 172 −12 Enterobacter cloacae CONTIG512 GTC ORF with score 532 to: (ai:7501734693) (or:Klebsiella pneumoniae) 4535405_c3_824 3852 20423 681 226 99 −3 Homo sapiens JC4525 (cl:unassigned ribonucleoprotein repeat- containing proteins:ribonucleoprotein repeat homology) (sr:, man) 321578I8_c3_826 3853 20424 1122 373 416 −39 Burkholderia P24129 (sr:,pseudomonas cepacia) (de:fusaric acid cepacia resistance protein fusd) 2236638_c3_829 3854 20425 699 232 94 −1 African clawed frog P20397 (sr:,african clawed frog) (de:nucleolin (protein c23)) 1261416_c3_831 3855 20426 447 148 157 −12 Klebsiella Contig525A GTC ORF with score 133 to: (ai:7500980859) pneumoniae (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) 32665956_c3_832 3856 20427 609 202 172 −13 Staphylococcus CONTIG078 GTC ORF with score 228 to: (ai:7000735514) epidermidis C (or:Enterococcus faecium) 26771086_c3_834 3857 20428 1077 358 291 −26 Enterobacter cloacae CONTIG513 GTC ORF with score 291 to: (ai:7000769632) (or:Pseudomonas aeruginosa) 12220968_c3_835 3858 20429 1437 478 152 −8 Plasmodium P04922 (sr:nuri,) (de:circumsporozoite protein knowlesi precursor (cs)) 33855276_c3_842 3859 20430 1632 543 251 −21 Klebsiella Contig506A GTC ORF with score 251 to: (ai:7000769640) pneumoniae (or:Pseudomonas aeruginosa) 15714456_c3_848 3860 20431 1113 370 123 −7 Klebsiella Contig478A GTC ORF with score 123 to: (ai:7000769646) pneumoniae (or:Pseudomonas aeruginosa) 14142842_c3_850 3861 20432 681 226 191 −14 equine herpesvirus D88734 (sr:equine herpesvirus 1 (strain:bk343, type 1 EVH-1 isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 10275332_c3_851 3862 20433 561 186 148 −9 Homo sapiens M94131 (sr:homo sapiens intestine cdna to mrna) (de:human mucin 2 (muc2) mrna, partial cds.) 14933433_c3_853 3863 20434 603 200 104 −6 Enterobacter cloacae CONTIG328 GTC ORF with score 104 to: (ai:7000769651) (or:Pseudomonas aeruginosa) 22477053_c3_854 3864 20435 1779 592 1255 −128 Pseudomonas Y15252 (de:pseudomonas aeruginosa narx, narl, nark1, aeruginosa nark2, narg, narh, narj,nari, nifm, moaa genes.) 33722580_c3_856 3865 20436 1224 407 113 −3 Orf virus B34768 2135200_c3_865 3866 20437 2403 800 2155 −223 Pseudomonas A56394 aeruginosa 16260968_c3_880 3867 20438 1206 401 32707306_c3_883 3868 20439 321 106 3313255_c3_884 3869 20440 345 115 206 −16 Drosophila S58776 (mp:3) melanogaster 35175761_f1_1 3870 20441 1782 593 110 −6 Enterobacter cloacae CONTIG500 GTC ORF with score 107 to: (ai:7000723201) (or:no gb taxonomy match) (de:human papillomavirus type 80 e6, e7, e1, e2, e4, 12, and 11 genes.) (nt:putative) 16886667_f1_4 3871 20442 486 161 103 −5 Klebsiella Contig559A GTC ORF with score 133 to: (ai:7000763331) pneumoniae (or:Pseudomonas aeruginosa) 24303183_f1_10 3872 20443 2484 827 1226 −125 Pseudomonas P42512 (de:fe(iii)-pyochelin receptor precursor) aeruginosa 4428783_f1_12 3873 20444 351 116 109 −6 Nannocystis exedens U66220 (de:nannocystis exedens unknown protein, partial cds and microsatellitesequence 7a140.) (nt:orf1) 9824033_f1_13 3874 20445 282 93 107 −6 Klebsiella Contig549A GTC ORF with score 109 to: (ai:7000796404) pneumoniae (or:Pseudomonas aeruginosa) 16922530_f1_14 3875 20446 1335 444 281 −22 Escherichia coli P36670 (de:ampg protein) 5135201_f1_15 3876 20447 525 174 105 −4 Klebsiella Contig482A GTC ORF with score 105 to: (ai:7000769697) pneumoniae (or:Pseudomonas aeruginosa) 30161541_f1_17 3877 20448 720 239 105 −2 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 31345717_f1_21 3878 20449 438 145 96 −2 no gb taxonomy P08392 (sr:type 1/17,) (de:ie175) (alpha-4 protein)) match 12754156_f1_22 3879 20450 1128 375 150 −7 Araneus diadematus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, partial cds.) 7302282_f1_24 3880 20451 498 165 91 −2 Klebsiella Contig557A GTC ORF with score 131 to: pneumoniae (fn:transcriptional regulation) (de:human herpesvirus 6 replication origin-binding protein (hdrfo),partial cds, helicase-primase component (hdrf1), virion protein(hdlf1), putative helicase (hdrf2), putative . . . 23634712_f1_28 3881 20452 1107 368 211 −15 Actinomadura JC5855 (ec:2.—.—.—) hibisca 16281456_f1_43 3882 20453 1254 417 79437_f1_45 3883 20454 1131 376 569 −55 Bacillus B69978 subtilis/Bacillus globigii 22039010_f1_56 3884 20455 2316 771 469 −42 Bradyrhizobium S39901 japonicum 22914506_f1_60 3885 20456 429 142 92 −2 Caenorhabditis Z81567 (de:caenorhabditis elegans cosmid k08c9, elegans complete sequence.) 5993926_f1_62 3886 20457 1419 472 743 −73 Bacillus P27675 (de:glutamine transport atp-binding protein stearothermophilus glnq) 10808341_f1_67 3887 20458 483 160 113 −5 Orf virus B34768 16453276_f1_69 3888 20459 1446 481 144 −9 Azospirillum X70360 (de:a.brasilense carr gene.) brasilense 11073341_f1_78 3889 20460 1110 369 118 −3 Micrococcus luteus JQ0405 32525661_f1_80 3890 20461 441 146 109 −6 Aspergillus Contig9367 GTC ORF with score 182 to: (ai:99171) fumigatus (or:Dictyostelium discoideum) (de:dictyostelium discoideum sp96 gene for spore coat protein sp96.) 35366662_f1_84 3891 20462 1800 599 160 −8 Plasmodium vivax M34697 (sr:p.vivax (strain thai; isolate nyu thai) sporozoite dna) (de:p.vivax circumsporozoite protein gene, complete cds.) (nt:circumsporozoite protein) 35675408_f1_88 3892 20463 1533 510 31922667_f1_89 3893 20464 1089 362 164 −10 Klebsiella Contig332A GTC ORF with score 532 to: (ai:7000846136) pneumoniae (or:Enterobacter cloacae) 5885388_f1_96 3894 20465 507 168 175 −13 Bacillus D70063 subtillis/Bacillus globigii 31898916_f2_99 3895 20466 891 296 204 −15 Yersinia Y12527 (de:y.enterocolitica irp1, irp3, irp4 and irp5 enterocolitica genes.) (nt:part of thc siderophore biosynthetic operon) 31838581_f2_100 3896 20467 1278 425 246 −18 Bos primigenius A90369 (cl:collagen alpha 1(i) chain:fibrillar collagen taurus carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, cattle) 31353291_f2_102 3897 20468 1605 534 176 −9 mice|C57BL/6xCBA/ Q01149 (sr:,mouse) (de:procollagen alpha 2(i) chain CaJ hybrid precursor) 11767881_f2_103 3898 20469 606 201 129 −6 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 16928958_f2_105 3899 20470 1530 509 2601 −270 Pseudomonas P42512 (de:fe(iii)-pyochelin receptor precursor) aeruginosa 29979l51_f2_106 3900 20471 2139 712 16301037_f2_111 3901 20472 1086 361 126 −8 Klebsiella Contig554A GTC ORF with score 324 to: (ai:7000842168) pneumoniae (or:Enterobacter cloacae) 36369407_f2_112 3902 20473 2472 823 31892556_f2_115 3903 20474 708 235 131 −6 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 79375_f2_118 3904 20475 183 60 16135040_f2_119 3905 20476 420 139 146 −9 Streptomyces P42712 (sr:,streptomyces alboniger) (ec:2.1.1.38) (de:o anulatus demethylpuromycin-o-methyltransferase,) 14588506_f2_122 3906 20477 4704 1567 135 −5 Plasmodium P04929 (de:histidine-rich glycoprotein precursor) lophurae 14973936_f2_127 3907 20478 408 135 140 −10 Klebsiella Contig486A GTC ORF with score 140 to: (ai:7000769809) pneumoniae (or:Pseudomonas aeruginosa) 32322818_f2_130 3908 20479 1134 377 136 −9 Enterobacter cloacae CONTIG508 GTC ORF with score 143 to: (ai:69657) (or:Human herpesvirus 4) (cl:epstein-barr virus nuclear antigen) 3579708l_f2_132 3909 20480 1320 439 35832332_f2_134 3910 20481 1749 582 190 −12 Klebsiella Contig508A GTC ORF with score 241 to: (ai:7000768896) pneumoniae (or:Pseudomonas aeruginosa) 35286566_f2_138 3911 20482 675 224 133 −6 Plasmodium simium Q03110 (de:circumsporozoite protein precursor (cs)) 30112635_f2_139 3912 20483 942 313 316 −28 Bacillus D69633 subtillis/Bacillus globigii 31532263_f2_140 3913 20484 1353 450 391 −36 Rhizobium Q52814 (sr:,biovar viciae) (de:general 1-amino acid leguminosarum transport permease protein aapm) 1259832_f2_146 3914 20485 852 283 276 −24 Azospirillum X70360 (de:a.brasilense carr gene.) (nt:orf2) brasilense 5165652_f2_147 3915 20486 1392 463 113 −3 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 32438531_f2_149 3916 20487 534 177 133 −7 Alphaherpesvirus P33485 (sr:kaplan,prv) (de:probable nuclear antigen) pseudorabies virus PRV 31770965_f2_154 3917 20488 1104 367 376 35 Pseudomonas AF012537 (de:pseudomonas aeruginosa acetyl-coa aeruginosa synthetase gene, partial cds; andarginine and ornithine binding protein (aotj), membrane protein(aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), andargr (argr) genes, complete cds.) ( . . . 31258255_f2_156 3918 20489 414 137 122 −6 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 19923578_f2_159 3919 20490 1875 624 1165 −118 Cyanobacterium S75122 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 16691657_f2_160 3920 20491 1578 525 12110713_f2_162 3921 20492 294 97 236 −20 Escherichia coli S48658 (ec:5.2.1.8) 11041708_f2_167 3922 20493 765 254 96 −5 Acinetobacter CONTIG199 GTC ORF with score 131 to: (ai:7501770022) baumannii C (or: Klebsiella pneumoniae) 5212692_f3_174 3923 20494 717 238 1175 −118 Pseudomonas AF074705 (de:pseudomonas aeruginosa aeruginosa dihydroaeruginoic acid synthetase (pche) andpyochelin synthetase (pchf) genes, complete cds.) (nt:peptide synthetase) 5964566_f3_177 3924 20495 1977 658 621 −60 Mycobacterium Q11018 (de:hypothetical abc transporter atp-binding tuberculosis protein cy02b10.12) 32679807_f3_178 3925 20496 1335 444 351 −31 Mycobacterium Q11019 (de:hypothetical abc transporter atp-binding tuberculosis protein cy02b10.13) 17057333_f3_179 3926 20497 417 138 250 −20 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 12619533_f3_182 3927 20498 303 100 91 −4 Homo sapiens PC4397 (sr:, man) 33723808_f3_185 3928 20499 423 140 106 −5 Schizo- Z99759 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c16c9.) (nt:spbc16e9.11c, putative pombe ubiquitin protein ligase,) 13954131_f3_186 3929 20500 1413 470 1750 −180 Pseudomonas P42514 (de:hypothetical 42.2 kd protein in fptb aeruginosa 3′region) 15720451_f3_188 3930 20501 696 231 95 −3 Clostridium Contig070H GTC ORF with score 293 to: (ai:7000787341) acetobutylicum (or:Pseudomonas aeruginosa) 16286458_f3_190 3931 20502 1371 456 30292625_f3_199 3932 20503 1224 407 183 −12 Aspergillus Contig9641 GTC ORF with score 197 to: (ai:7000789067) fumigatus (or:Pseudomonas aeruginosa) 12916330_f3_206 3933 20504 1452 483 116 −4 Klebsiella Contig558A GTC ORF with score 282 to: (ai:7000758048) pneumoniae (or:Pseudomonas aeruginosa) 33645791_f3_210 3934 20505 492 163 94 −2 equine herpesvirus D88734 (sr:equine herpesvirus 1 (strain:bk343, type 1 EVH-1 isolate:3f clone) dna) (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 26427041_f3_223 3935 20506 822 273 119 −4 Herpesvirus papio U23857 (fn:binds to orip to permit replication of the) (de:herpesvirus papio brrf2 homolog gene, partial cds, ebna1, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebna1 of epstein-barr v . . . 1188201_f3_224 3936 20507 1107 368 447 −50 Escherichia coli P07862 (ec:6.3.2.4) (de:synthetase)) 7065900_f3_229 3937 20508 501 166 237 −20 Acinetobacter CONTIG120 GTC ORF with score 237 to: (ai:7000769911) baumannii C (or:Pseudomonosa aeruginosa) 23600802_f3_233 3938 20509 2061 686 188 −11 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 16658331_f3_234 3939 20510 897 298 421 −39 stem-nodulating P26487 (de:transcriptional regulatory protein fixj) bacterium 13166428_f3_237 3940 20511 975 324 361 −33 Bacillus E69633 subtilis/Bacillus globigii 35439768_f3_240 3941 20512 501 166 112 −4 Oryctolagus P16258 (sr:,rabbit) (de:oxysterol-binding protein) cuniculus 31277263_f3_241 3942 20513 1173 390 350 −32 Streptomyces P27744 (de:isopenicillin n synthetase (ipns)) lactamdurans 16426943_f3_253 3943 20514 1362 453 34614431_f3_257 3944 20515 621 206 211 −17 Klebsiella Contig535A GTC ORF with score 211 to: (ai:7000769939) pneumoniae (or:Pseudomonas aeruginosa) 2475657_f3_258 3945 20516 1434 477 328 −30 Enterobacter cloacae CONTIG293 GTC ORF with score 328 to: (ai:7000769940) (or:Pseudomonas aeruginosa) 32636465_f3_259 3946 20517 417 138 90 −3 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline- rich cell wall protein mrna, completecds.) 11769382_f3_260 3947 20518 435 144 93 −3 Drosophila virilis A60095 (cl:salivary glue protein) (nip:x16a) 31928890_f3_263 3948 20519 819 272 129 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 10052266_f3_269 3949 20520 417 138 120 −6 Homo sapiens O00268 (sr:,human) (de:(tafii135) (tafii-130) 20958167_f3_271 3950 20521 594 197 418 −39 Escherichia coli P39332 (de:hypothetical 14.6 kd protein in pyr1-argi intergenic region (f131)) 16266430_c1_283 3951 20522 897 298 418 −39 Streptomyces AL031155 (de:streptomyces coelicolor cosmid 3a7.) coelicolor (nt:sc3a7.09, probable exonuclease,: 259 aa;) 24022637_c1_285 3952 20523 957 318 478 −45 Escherichia coli P37641 (de:hypothetical transcriptional regulator in tref-kdgk intergenic region) 1033467_c1_286 3953 20524 1626 541 902 −90 Lysobacter AF083621 (fn:arginyl endopeptidase) (de:lysobacter enzymogenes enzymogenes endoproteinase arg-c precursor (ler) gene,complete cds; and s3_orf2 pseudogene, partial sequence.) (nt:similar to lysobacter enzymogenes and achromobacter) 32679541_c1_287 3954 20525 246 81 16914143_c1_289 3955 20526 528 175 245 −21 Acinetobacter CONTIG230 GTC ORF with score 266 to: (ai:7000806155) baumannii C (or:Pseudomonas aeruginosa) 16119517_c1_290 3956 20527 843 280 171 −12 Streptomyces U10405 (de:streptomyces purpurascens atcc 25489 purpurascens rdmb (rdmb), rdmc (rdmc), rdmd(rdmd), and rdme (rdme) genes, complete cds, and rdma (rdma) andrdmf (rdmf) genes partial cds) (nt:required for modification on 10-position of) 29975691_c1_291 3957 20528 672 223 153 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 20035062_c1_296 3958 20529 1521 506 95 −4 longfin squid S56117 (sr:,longfin squid) 36026686_c1_301 3959 20530 957 318 116 −4 Alphaherpesvirus Q85232 (sr:kaplan,prv) (de:transcriptional regulator pseudorabies virus ie63 homolog (protein ul54)) PRV 3338317_c1_303 3960 20531 1479 492 11854205_c1_304 3961 20532 588 195 166 −11 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem- 11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 15083342_c1_305 3962 20533 1581 526 1104 −112 Escherichia coli P23883 (ec:1.2.1.3) (de:putative aldehyde dehydrogenase,) 34271057_c1_308 3963 20534 519 172 113 −6 Klebsiella Contig452A GTC ORF with score 113 to: (ai:7000769990) pneumoniae (or:Pseudomonas aeruginosa) 10366705_c1_309 3964 20535 861 286 127 −5 Mycobacterium AF027770 (de:mycobacterium smegmatis iron uptake smegmatis genes, fxba (fxba) gene partial cds and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf)genes, complete cds.) (nt:similar to membrane b . . . 12510056_c1_314 3965 20536 2328 775 4338567_c1_316 3966 20537 633 210 144 −8 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:org; no developmental phenotype) 35820831_c1_320 3967 20538 879 292 148 −7 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 6761057_c1_325 3968 20539 465 154 124 −8 Klebsiella Contig486A GTC ORF with score 124 to: (ai:7000770007) pneumoniae (or:Pseudomonas aeruginosa) 26754191_c1_329 3969 20540 825 274 256 −22 Bacillus D69856 subtilis/Bacillus globigii 25957211_c1_330 3970 20541 360 119 187 −14 Bacillus D69856 subtilis/Bacillus globigii 24469776_c1_332 3971 20542 453 150 94 −2 migratory locust AJ000390 (sr:migratory locust) (de:locusta migratoria mrna for nachr alpha1 subunit.) 10828933_c1_336 3972 20543 462 153 111 −5 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 25574057_c1_338 3973 20544 921 306 118 −4 Caenorhabdills U41538 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid r04e5.) (nt:proline rich; coded for by c. elegans cdna) 32525331_c1_342 3974 20545 549 182 892 −89 Pseudomonas AP005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to pseudomonas fluorescens gene product) 16994787_c1_343 3975 20546 1896 631 1072 −1 08 Pseudomonas AP005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to isochorismatases) 7307281_c1_346 3976 20547 942 313 982 −99 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to pseudomonas fluorescens phzf gene) 22291633_c1_351 3977 20548 2349 782 117 −3 Molluscum L10127 (sr:molluscum contagiosum virus type 1 dna) contagiosum virus (de:molluscum contagiosum virus type 1 orf1 subtype 1 and orf2 dna.) (nt:orf17) 13027153_c1_352 3978 20549 426 141 107 −5 Homo sapiens B35363 (sr:, man) 16116431_c1_354 3979 20550 723 240 135 −6 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain uganda-1102) (type 6/strain ie2hom mrna, complete cds.) (nt:similar to the Uganda-1102) immediate-early 2 protein of human) 16304168_c1_356 3980 20551 765 254 114 −3 infectious bovine Z78205 (de:bovine herpesvirus type 1 ul22-35 genes.) rhinotracheitis virus (nt:very large tegument protein) 31930167_c1_357 3981 20552 858 285 172 −9 equine herpesvirus AP030027 (fn:very large tegument protein) (de:equine type 4 EHV-4 herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene ul36 and vzv gene 22) 31501040_c1_359 3982 20553 948 315 233 −19 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 26798888_c1_360 3983 20554 1077 358 176 −10 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 16275791_c2_368 3984 20555 1353 450 134 −5 Homo sapiens X99897 (sr:human) (de:h.sapiens mrna for p/q-type calcium channel alpha1 subunit.) (nt:p/q-type; cacn11a4) 16930340_c2_370 3985 20556 354 117 112 −5 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 14947890_c2_382 3986 20557 261 86 92 −4 Enterobacter cloacae CONTIG450 GTC ORF with score 137 to: (ai:7500981187) (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid 16265786_c2_385 3987 20558 1419 472 97 −3 Aspergillus Contig9732 GTC ORF with score 119 to: (ai:7000786467) fumigatus (or:Pseudomonas aeruginosa) 12386468_c2_389 3988 20559 801 266 808 −81 Enterobacter cloacae CONTIG293 GTC ORF with score 910 to: (ai:7501788494) (or:Klebsiella pneumoniae) 11994593_c2_390 3989 20560 666 221 196 −15 Saccharomyces P36087 (sr:,baker's yeast) (de:hypothetical 19.8 kd cerevisiae protein in lhs1-nup100 intergenic region) 21896062_c2_394 3990 20561 1674 558 262 −20 Streptomyces AL031225 (de:streptomyces coelicolor cosmid 8b7.) coelicolor (nt:sc8b7.07c, possible oxidoreductase,: 475 aa;) 5099215_c2_395 3991 20562 477 158 129 −7 Escherichia coli P37906 (ec:1.—.—.—) (de:probable oxidoreductase ordl,) 15057662_c2_396 3992 20563 1344 447 807 −80 Escherichia coli P31679 (de:region (orf65/66)) 31894657_c2_397 3993 20564 972 323 108 −6 Aspergillus Contig10074 GTC ORF with score 123 to: (ai:82733) fumigatus (or:Gallus gallus) (sr:gallus gallus (strain white leghorn, sub_species domesticus) (de:gallus gallus domesticus aortic lysyl oxidase mrna, complete cds.) 16253956_c2_399 3994 20565 234 77 91 −5 Aspergillus Contig9333 GTC ORF with score 136 to: (ai:203141) fumigatus (or:Rattus norvegicus) (sr:, norway rat) 12925705_c2_400 3995 20566 537 178 153 −10 human berpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 16150766_c2_403 3996 20567 1734 577 125 −5 Schizo- Z95620 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c3d6.) (nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 36041656_c2_405 3997 20568 600 199 160 −12 Klebsiella Contig549A GTC ORF with score 224 to: (ai:7000779823) pneumoniae (or:Pseudomonas aeruginosa) 16973958_c2_411 3998 20569 441 146 129 −7 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86 region ie-b) 4069501_c2_412 3999 20570 1320 439 12367052_c2_414 4000 20571 1920 639 113 −3 Rattus norvegicus B48013 (cl:proline-rich protein) (sr:, norway rat) 24027182_c2_415 4001 20572 888 295 280 −24 Bacillus G69997 subtilis/Bacillus globigii 16304708_c2_416 4002 20573 1326 441 165 −9 Klebsiella Contig462A GTC ORF with score 486 to: (ai:7000833080) pneumoniae (or:Enterobacter cloacae) 16807333_c2_417 4003 20574 435 144 129 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35195252_c2_423 4004 20575 567 188 97 −3 Escherichia coli P77751 (de:hypothetical 17.9 kd protein in csie-glya intergenic region) 15798543_c2_424 4005 20576 1398 465 124 −4 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrh (orf 3)) 22080391_c2_425 4006 20577 4284 1427 751 −73 Pseudomonas X99514 (fn:outer membrane component of multidrug aeruginosa efflux) (de:p.aeruginosa mexe, mexf & oprn genes.) 26355 192_c2_431 4007 20578 1359 452 2106 −218 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to plant phospho-2-keto-3 deoxyheptonate) 16297881_c2_434 4008 20579 1731 576 314 −24 Micrococcus luteus JQ0405 34626907_c2_435 4009 20580 294 97 104 −5 Mycobacterium Z83858 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 130/162.) (nt:rv2944, (rntcy24g1.05c), len: 238 aa. possible) 16020662_c2_436 4010 20581 285 94 461 −44 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to pseudomonas fluorescens phzf gene) 13179806_c2_438 4011 20582 444 147 97 −3 Alphaherpesvirus P07645 (sr:rice,prv) (de:glycoprotein gp50) pseudorabies virus PRV 31675457_c2_439 4012 20583 1269 422 300 −26 Acinetobacter sp. AF009672 (de:acinetobacter sp. adp1 vanillate ADP1 demethylase region, vanillatedemethylase (vanb) and vanillate demethylase (vana) genes, completecds.) (nt:similar to salicylate hydroxylase; orf7) 16253456_c2_441 4013 20584 1077 358 103 −2 Pneumocystis carinii JC2301 22945776_c2_443 4014 20585 951 316 146 −7 Molluscum L10127 (sr:molluscum contagiosum virus type 1 dna) contagiosum virus (de:molluscum contagiosum virus type 1 orf1 subtype 1 and orf2 dna.) (nt:orf17) 33650458_c2_445 4015 20586 2223 740 132 −4 Molluscum U60315 (de:molluscum contagiosum virus subtype 1, contagiosum virus complete genome.) (nt:contains large predicted subtype 1 non-glabular regions and) 36442711_c2_447 4016 20587 2091 696 125 −4 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 16286683_c2_448 4017 20588 666 221 115 −4 Canis familiaris S33121 (cl:homeotic protein cdp:cut repeat homology:homeobox homology) (sr:, dog) 31754036_c3_450 4018 20589 846 281 526 −50 Pseudomonas P42512 (de:fe(iii)-pyochelin receptor precursor) aeruginosa 2135436_c3_452 4019 20590 945 314 187 −12 Pyrococcus AP000006 (sr:pyrococcus horikoshii (strain:ot3) dna, horikoshii clone:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) (nt:similar to owl:bsz940436 percent identity: 51.656) 3402041_c3_453 4020 20591 699 232 272 −24 Bacillus H69808 subtilis/Bacillus globigii 16022580_(—)c3_454 4021 20592 1194 397 108 −3 mice|C57BL/6xCBA/ C29149 (cl:proline-rich protein) (sr:, house mouse) CaJ hybrid 26218826_c3_455 4022 20593 1047 348 100 −5 Enterococcus CONTIG108 GTC ORF with score 672 to: (ai:7000758623) faecalis (or:Pseudomonas aeruginosa) 519776_c3_460 4023 20594 1395 464 16073407_c3_461 4024 20595 1374 457 809 −80 Pseudomonas putida AF029714 (de:pseudomonas putida repressor (phan), regulatory protein (pham),enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad),phenylacetyl-coa ligase (phae), ring-oxidation . . . 13019158_c3_462 4025 20596 1824 607 413 −39 Klebsiella Contig549A GTC ORF with score 1011 to: pneumoniae (ai:7000843851) (or:Enterobacter cloacae) 24652057_c3_467 4026 20597 1269 422 4401557_c3_468 4027 20598 759 252 166 −12 Bacillus G69783 subtilis/Bacillus globigii 33864407_c3_473 4028 20599 1005 334 337 −30 Escherichia coli P75682 (de:hypothetical 33.3 kd protein in perr-argf intergenic region) 13094758_c3_474 4029 20600 1011 336 129 −8 Aspergillus Contig8378 GTC ORF with score 143 to: (ai:7000780803) fumigatus (or:Pseudomonas aeruginosa) 32672705_c3_475 4030 20601 1881 626 249 −18 Streptomyces AJ007932 (de:streptomyces argillaceus mithramycin argillaceus biosynthetic genes.) 16500006_c3_481 4031 20602 741 246 125 −4 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 32707666_c3_488 4032 20603 441 146 144 −9 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 33693781_c3_490 4033 20604 1668 555 1299 −132 Brassica napus X94625 (sr:rape) (de:b.napus mrna for amp-binding protein.) 16510208_c3_491 4034 20605 1899 632 764 −76 Mycobacterium AL021184 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 64/162.) (nt:rv1467c, (mtv007.14c), len: 609.fade15, possible) 14495841_c3_492 4035 20606 756 251 169 −1o Borcogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26442201_c3_496 4036 20607 444 147 118 −6 mice|C57BL/6xCBA/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- CaJ hybrid prolines- 101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 10814192_c3_499 4037 20608 867 288 541 −52 Escherichia coli P77309 (de:hypothetical transcriptional regulator in uxab-marr intergenic region) 36597958_c3_500 4038 20609 786 261 115 −4 mice|C57BL/6xCBA/ P54320 (sr:,mouse) (de:elastin precursor CaJ hybrid (tropoelastin)) 13147705_c3_504 4039 20610 1200 399 439 −41 Haemophilus G64100 (cl:lipoyl/biotin-binding homology) influenzae 16114092_c3_505 4040 20611 3102 1033 2179 −226 Haemophilus 957124 (de:hypothetical protein hi0895) influenzae 12635091_c3_506 4041 20612 471 156 130 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34479180_c3_508 4042 20613 1248 415 103 −2 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 21954466_c3_513 4043 20614 534 177 905 −91 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon completesequence.) (nt:similar to pseudomonas fluorescens gene product) 36416655_c3_515 4044 20615 495 164 106 −4 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene domesticus coding for phosvitin, exons 23 and24.) 12000840_c3_517 4045 20616 2562 853 3180 −9999 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to bacterial type-i glutamine) 16683408_c3_518 4046 20617 1521 506 1113 −113 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to bacterial pyridoxamine-5′- phosphate) 35833556_c3_525 4047 20618 663 220 125 −5 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) type EVH-1 (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 16300908_c3_527 4048 20619 2493 830 115 −2 mice|C57BL/6xCBA/ Y17034 (fn:zinc-finger cag /glutamine-repeat protein) CaJ hybrid (sr:house mouse) (de:mus musculus bassoon gene, exon 1 and joined cds.) 16285416_c3_529 4049 20620 276 91 125 −8 Klebsiella Contig503A GTC ORF with score 152 to: (ai:7000839596) pneumoniae (or:Enterobacter cloacae) 34473917_c3_530 4050 20621 1482 493 218 −14 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 32629166_c3_533 4051 20622 492 163 134 −8 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 34492218_f1_1 4052 20623 525 174 172 −12 Caenorhahditis AF078790 (de:caenorhabditis elegans cosmid f36h12.) elegans (nt:coded for by c. elegans cdna cemsf30f) 14730155_f1_5 4053 20624 522 173 130 −7 equine herpesvirus p88733 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 14979202_f1_19 4054 20625 1152 383 127 −5 Schizo- AL021746 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c1e8.) (nt:spbc1e8.05, unknown; serine pombe rich protein,) 9852293_f1_21 4055 20626 813 270 153 −8 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 31353955_f1_22 4056 20627 1686 561 2325 −241 Pseudomonas Q51397 (de:outer membrane protein oprj precursor) aeruginosa 16448781_f1_36 4057 20628 1305 434 180 −11 Escherichia coli C64816 31722042_f1_37 4058 20629 663 220 815 −81 Pseudomonas L08966 (fn:protein activator for n-alkane oxidation) aeruginosa (sr:pseudomonas aeruginosa (library: dsm2659) dna) (de:pseudomonas aeruginosa protein activator gene, complete cds.) 12527013_f1_42 4059 20630 1221 406 277 −24 Klebsiella Contig559A GTC ORF with score 277 to: (ai:7000770260) pneumoniae (or:Pseudomonas aeruginosa) 35261416_f1_47 4060 20631 414 137 104 −4 herpes simplex virus Z86099 (fn:immediate early protein; transcriptional) type 2 HSV-2 (de:herpes simplex virus type 2 (strain hg52), complete genome.) 32237631_f1_50 4061 20632 1893 630 24650458_f1_54 4062 20633 1602 533 1856 −191 Escherichia coli P38035 (de:transcriptional regulatory protein rtcr) 16657253_f1_55 4063 20634 684 227 100 −5 Klebsiella Contig356A GTC ORF with score 170 to: (ai:7000829481) pneumoniae (or:Enterobacter cloacae) 4859705_f1_56 4064 20635 798 266 179 −14 Plasmid pAH4 JC2320 16273951_f2_59 4065 20636 486 161 98 −3 Homo sapiens U15177 (sr:human) (de:human cosmid cri-jc2015 at d10s289 in 10sp13.) (nt:orf) 35730213_f2_60 4066 20637 1461 486 29806456_f2_69 4067 20638 1383 460 105 −5 Acinetobacter CONTIG217 GTC ORF with score 105 to: (ai:7000770287) baumannii C (or:Pseudomonas aeruginosa) 35833558_f2_71 4068 20639 516 171 124 −7 Pseudomonas A36128 aeruginosa 34073893_f2_73 4069 20640 498 165 156 −11 Klebsiella Contig526A GTC ORF with score 156 to: (ai:7000770291) pneumoniae (or:Pseudomonas aeruginosa) 22781965_f2_83 4070 20641 897 298 94 −1 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 35260780_f2_84 4071 20642 1275 424 457 −43 Cyanobacterium S76946 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803,) synechocystis 15725166_f2_86 4072 20643 1254 417 163 −8 Mycobacterium AF034152 (de:mycobacterium smegmatis exochelin gene smegmatis cluster, exit (exit) andfxbb (fxbb) genes, complete cds; and fxbc (fxbc) gene, partial cds.) (nt:abc transporter; this abc transporter probably) 32683156_f2_88 4073 20644 444 147 119 −8 Klebsiella Contig405A GTC ORF with score 181 to: (ai:7000795864) pneumoniae (or:Pseudomonas aeruginosa) 33706961_f2_92 4074 20645 1362 453 331 −30 Haemophilus P43838 (de:outer membrane protein p1 precursor (omp influenzae p1)) 34432062_f2_93 4075 20646 1353 450 1562 −160 Escherichia coli P00370 (ec:1.4.1.4) (de:nadp-specific glutamate dehydrogenase, (nadp-gdh)) 3146055_f2_101 4076 20647 1251 416 14588405_f2_103 4077 20648 339 112 94 −4 Homo sapiens Z34277 (sr:human) (de:h.sapiens (jer47) muc5ac mrna for mucin (partial).) 14925955_f2_104 4078 20649 1728 575 515 −49 Streptomyces AL031035 (de:streptomyces coelicolor cosmid 6a9.) coelicolor (nt:sc6a9.02, unknown, : 213 aa; some similarity to) 26770313_f3_107 4079 20650 1254 417 747 −74 Escherichia coli P32049 (de:hypothetical 27.3 kd protein in ansb-muty intergenic region (f239)) 12629030_f3_108 4080 20651 1509 502 1035 −104 Pseudomonas U10470 (de:pseudomonas fluorescens pha fluorescens depolymerase (phaz) gene, complete cds.) 24897715_f3_110 4081 20652 1059 352 277 −24 Enterobacter cloacae CONTIG508 GTC ORF with score 396 to: (ai:7501774741) (or:Klebsiella pneumoniae) 36504206_f3_111 4082 20653 297 98 112 −6 Klebsiella Contig526A GTC ORF with score 396 to: (ai:7000844509) pneumoniae (or:Enterobacter cloacae) 14558253_f3_112 4083 20654 789 262 209 −17 Enterobacter cloacae CONTIG508 GTC ORF with score 209 to: (ai:7000770330) (or:Pseudomonas aeruginosa) 6511451_f3_118 4084 20655 1377 458 4969591_f3_126 4085 20656 1800 599 2257 −234 Haemophilus P45127 (de:abc transporter atp-binding protein hi 1252) influenzae 34501717_f3_128 4086 20657 738 245 553 −53 Bacillus D69858 (cl:unassigned atp-binding cassette proteins:atp subtilis/Bacillus binding cassette homology) globigii 17057081_f3_131 4087 20658 1680 559 157 −8 Cyanobacterium S75812 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 2344206_f3_132 4088 20659 762 253 172 −11 Epstein-Barr virus P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 nuclear protein) 35574055_f3_136 4089 20660 759 252 116 −4 Dictyostelium P36417 (sr:,slime mold) (de:g-box binding factor discoideum (gbf)) 11041456_f3_142 4090 20661 741 246 102 −2 Chironomus tentans A45294 32633518_f3_152 4091 20662 501 166 118 −5 Nephila clavipes AF027973 (de:nephila clavipes flagelliform silk protein (flag) mrna, partialcds.) 16113266_c1_156 4092 20663 384 127 23957937_c1_159 4093 20664 1773 590 108 −3 Escherichia coli A30282 (cl:glycerol-3-phosphate regulon repressor) (mp:75 min) 31505206_c1_163 4094 20665 1257 418 1471 −151 Escherichia coli P46850 (de:rtcb protein) 29791716_c1_164 4095 20666 849 282 574 −56 Bacillus G69758 subtilis/Bacillus globigii 16928818_c1_166 4096 20667 564 187 97 −2 Chlamydomonas P93107 (de:flagellar wd-repeat protein pf20) reinhardtii strain UTEX 1061 34025166_c1_169 4097 20668 1194 397 185 −11 Canadian hard S02262 (cl:glutenin) (sr:, common wheat) winter wheat 16900342_c1_170 4098 20669 447 148 130 −9 Enterobacter cloacae CONTIG498 GTC ORF with score 130 to: (ai:7000770388) (or:Pseudomonas aeruginosa) 32660083_c1_175 4099 20670 669 222 110 −3 Nephila clavipes A36068 12552341_c1_178 4100 20671 1347 448 16187568_c1_187 4101 20672 360 119 34117291_c1_188 4102 20673 2019 672 114 −3 Caenorhabditis Z79694 (de:caenorhabditis elegans cosmid c15a11, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen) 35587830_c1_190 4103 20674 597 198 375 −34 Pseudomonas P25254 (de:hypothetical protein in proc 3′region aeruginosa (fragment)) 10650905_c1_191 4104 20675 2181 726 214 −14 Homo sapiens S80905 (sr:human subject “r.s.” peripheral blood leukocytes) (de:prb2 (prb21 con1+)=con1 {exon 3} (human, peripheral bloodleukocytes, subject ‘r.s.’, genomic mutant, 1179 nt).) (nt:salivary concanavalin-a binding protein; method:) 13004130_c1_192 4105 20676 489 162 152 −10 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16491657_c1_193 4106 20677 645 214 110 −4 Lactococcus lactis U80599 (fn:unknown) (de:lactococcus lactis orfa and (SUBSP. orfb genes, partial cds.) (nt:orfa; similar to CREMORIS) synechocytis sp. methyltransferase) 11210456_c1_194 4107 20678 855 284 132 −7 Mycobacterium Z95557 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 153/162.) (nt:rv3611, (mtcy07h7b.11c), len: 217. possible orf) 14660166_c1_195 4108 20679 1224 407 131 −5 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase- binding protein related protein mrna,partial cds.) (nt:divergently related to myrosinase binding protein;) 14947632_c1_196 4109 20680 366 121 31890667_c2_208 4110 20681 513 170 106 −4 Caenorhabditis U88170 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid c10g11.) (nt:coded for by c. elegans cdna yk65e4.5; coded for by) 16802066_c2_209 4111 20682 405 134 97 −3 Sus scrofa domestica I47141 (sr:, domestic pig) 24423567_c2_214 4112 20683 1209 402 220 −15 blue mussel AF015539 (sr:blue mussel) (de:mytilus edulis precollagen p (precol-p) mrna, complete cds.) 16275830_c2_215 4113 20684 501 166 142 −8 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 13094541_c2_218 4114 20685 558 185 99 −3 Orf virus D34768 35677007_c2_220 4115 20686 453 150 24414193_c2_221 4116 20687 1053 350 1807 −186 Pseudomonas P14532 (ec:1.11.1.5) (de:peroxidase) (ccp)) aeruginosa 16533290_c2_222 4117 20688 462 153 102 −4 Drosophila erecta P13730 (sr:,fruit fly) (de:salivary glue protein sgs-3 precursor) 14191002_c2_232 4118 20689 1404 467 110 −3 Orf virus B34768 16504441_c2_234 4119 20690 966 321 219 −16 Klebsiella Contig516A GTC ORF with score 124 to: pneumoniae (de:mycobacterium smegmatis iron uptake genes, fxba (fxba) gene,partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf)genes. complete cd.) (nt:similar to . . . 31895312_c2_235 4120 20691 1761 586 205 −15 Pseudomonas JQ0133 aeruginosa 32683458_c2_236 4121 20692 798 265 553 −53 Pseudomonas P32265 (de:transcriptional regulatory protein nfxb) aeruginosa 16113166_c2_242 4122 20693 2037 678 20183406_c2_247 4123 20694 1515 504 505 −48 Escherichia coli P52061 (de:hypothetical 21.0 kd protein in gshb-ansb intergenic region (o197)) 6366658_c2_248 4124 20695 1275 424 1068 −108 Escherichla coli P52062 (de:hypothetical 42.6 kd protein in gshb-ansb intergenic region (o378)) 16057080_c2_249 4125 20696 336 111 16103968_c2_250 4126 20697 2775 925 277 −23 Enterobacter cloacae CONTIG508 GTC ORF with score 452 to: (ai:7501774954) (or:Klebsiella pneumoniae) 6757637_c3_256 4127 20698 1695 564 697 −69 Anabaenaflos-aquae I39620 (strain IUCC 1444) 20017266_c3_258 4128 20699 1128 375 128 −6 Klebsiella Contig558A GTC ORF with score 129 to: (ai:7500892091) pneumoniae (or:Mus spretus) (sr:western wild mouse) (de:mus spretus sex determining protein (sry) gene, complete cds.) (nt:hmg box transcription factor) 26680383_c3_259 4129 20700 1776 591 849 −85 Escherichia coli P46849 (ec:6.5.1.4) (de:cyclase) (rna cyclase)) 34072780_c3_261 4130 20701 639 212 121 −4 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 33866708_c3_263 4131 20702 1497 498 680 −67 Enterobacter cloacae CONTIG498 GTC ORF with score 982 to: (ai:7501798241) (or:Klebsielia pneumoniae) 35569566_c3_266 4132 20703 1266 421 35631403_c3_268 4133 20704 222 73 34619577_c3_269 4134 20705 240 79 31303885_c3_270 4135 20706 513 170 130 −7 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:org; no developmental phenotype) 14947808_c3_271 4136 20707 741 246 145 −8 Streptomyces fradiae P20186 (de:hypothetical 35.5 kd protein in transposon tn4556) 3213532_c3_273 4137 20708 1104 367 103 −5 Enterobacter cloacae CONTIG494 GTC ORF with score 138 to (ai:7000787040) (or:Pseudomonas aeruginosa) 25566682_c3_274 4138 20709 465 154 196 −16 Enterobacter cloacae CONTIG419 GTC ORF with score 91 to: (ai:7500982114) (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna, cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) 432075_c3_278 4139 20710 261 86 94 −5 Enterobacter cloacae CONTIG458 GTC ORF with score 552 to: (ai:7501739628) (or:Klebsiella pneumoniae) 23906912_c3_286 4140 20711 516 171 448 −42 Pseudomonas P22008 (ec:1.5.1.2) (de:pyrroline-5-carboxylate aeruginosa reductase, (p5cr) (p5c reductase)) 125834818_c3_287 4141 20712 897 298 244 −21 Escherichia coli P52060 (de:hypothetical 10.9 kd protein in gshb-ansh intergenic region (o100)) 2474132_c3_293 4142 20713 1173 390 888 −89 Leptospira meyeri Y10744 (fn:involved in methionine biosynthesis) (de:l. meyeri mety and metx genes.) 2151888_c3_295 4143 20714 609 202 12604656_c3_298 4144 20715 504 167 141 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 19922876_f1_1 4145 20716 1734 577 722 −86 Bacillus C69794 subtilis/Bacillus globigii 12970658_f1_5 4146 20717 387 128 93 −4 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) 14194411_f1_6 4147 20718 888 295 238 −20 Klebsiella Contig321A GTC ORF with score 238 to: (ai:7000770528) pneumoniae (or:Pseudomonas aeruginosa) 2582506_f1_7 4148 20719 1113 370 800 −79 Escherichia coli P31134 (de:putrescine transport atp-binding protein potg) 24814163_f1_8 4149 20720 885 294 192 −14 Haemophilus P45170 (de:spermidine/putrescine transport system influenzae permease protein potb) 35239682_f1_10 4150 20721 618 205 16270833_f1_11 4151 20722 240 79 93 −4 Chlamydia AE001324 (de:chlamydia trachomatis section 51 of 87 of trachomatis the complete genome.) 36505211_f1_14 4152 20723 1800 599 21922706_f1_18 4153 20724 1107 368 325 −29 Aquifex aeolicus D70462 787932_f1_22 4154 20725 603 200 126 −8 Klebsiella Contig366A GTC ORF with score 126 to: (ai:7000770544) pneumoniae (or:Pseudomonas aeruginosa) 36136437_f1_23 4155 20726 1137 378 19710930_f1_41 4156 20727 942 313 452 −43 Cyanobacterium S77111 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) synechocystis 16986542_f1_42 4157 20728 1302 433 1177 −119 Escherichia coli P31064 (de:hypothetical 44.4 kd protein in amya-flie intergenic region (orf 48)) 36523563_f1_47 4158 20729 1347 448 524 −50 Schizo- L37084 (sr:schizosaccharomyces pombe cdna to mrna) saccharomyces (ec:4.2.1.11) (de:schizosaccharomyces pombe pombe phosphopyruvate hydratase mrna, completecds.) 6847536_f1_48 4159 20730 1107 368 628 −62 Klebsiella Contig316A GTC ORF with score 628 to: (ai:7000770570) pneumoniae (or:Pseudomonas aeruginosa) 5960433_f1_56 4160 20731 585 194 101 −3 Caenorhabditis Z71177 (de:caenorhabditis elegans cosmid ac3, elegans complete sequence.) (nt:similar to collagen; cdna est yk362c2.5 comes from) 9816715_f1_57 4161 20732 948 315 128 −8 Enterobacter cloacae CONTIG465 GTC ORF with score 128 to: (ai:7000770579) (or:Pseudomonas aeruginosa) 7081651_f1_58 4162 20733 2133 710 1381 −141 Klebsiella Contig395A GTC ORF with score 1409 to: pneumoniae (ai:7000832342) (or:Enterobacter cloaecae) 22148291_f1_59 4163 20734 2115 704 434 −40 Klebsiella Contig451A GTC ORF with score 434 to: (ai:7000770581) pneumoniae (or:Pseudomonas aeruginosa) 29728955_f1_66 4164 20735 255 84 190 −15 Klebsiella Contig138A GTC ORF with score 323 to: (ai:7000832349) pneumoniae (or:Enterobacter cloacae) 32160632_f1_68 4165 20736 1530 509 196 −15 Enterobacter cloacae CONTIG465 GTC ORF with score 370 to: (ai:7501728285) (or:Klebsiella pneumoniae) 35446028_f1_69 4166 20737 885 294 169 −11 Enterobacter cloacae CONTIG465 GTC ORF with score 520 to: (ai:7501728287) (or:Klebsiella pneumoniae) 33880200_f1_75 4167 20738 333 110 103 −4 equine herpesvirus D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for membrane glycoprotein, complete cds.) 2635341_f1_78 4168 20739 1488 495 14182083_f1_83 4169 20740 456 151 225 −19 Enterobacter cloacae CONTIG465 GTC ORF with score 225 to: (ai:7000770605) (or:Pseudomonas aeruginosa) 2084828_f1_84 4170 20741 999 332 515 −50 Klebsiella Contig065A GTC ORF with score 995 to: (ai:7000832458) pneumoniae (or:Enterobacter cloacae) 11189777_f1_85 4171 20742 858 285 911 −91 Escherichia coli P07906 (ec:3.4.11.18) (de:methionine aminopeptidase, (map) (peptidase m)) 36114511_f1_88 4172 20743 2406 801 868 −87 Azospirillum X92496 (de:azospirillum brasilense partial ubih-like brasilense gene, glnz gene, aat-likegene & partial ftsk- like gene.) (nt:putative) 35806417_f1_89 4173 20744 720 239 103 −4 Klebsiella Contig504A GTC ORF with score 103 to: (ai:7000770611) pneumoniae (or:Pseudomonas aeruginosa) 14944831_f1_92 4174 20745 621 206 126 −6 Enterococcus CONTIG520 GTC ORF with score 153 to: (ai:7000731853) faecium C (or:Streptococcus pneumoniae) 31852031_f1_96 4175 20746 450 149 260 −22 Escherichia coli P24178 (de:hypothetical 13.6 kd protein in acrd-dape intergenic region) 31930458_f1_97 4176 20747 636 211 242 −20 Pseudomonas P38102 (de:hypothetical 23.3 kd protein in cara-carb aeruginosa intergenic region) 29948457_f1_99 4177 20748 1197 398 793 −79 Bacillus F70019 subtilis/Bacillus globigii 15725777_f1_101 4178 20749 825 274 175 −11 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12515768_f1_116 4179 20750 549 182 117 −5 Dictyostelium P35085 (sr:,slime mold) (de:calcium binding protein) discoideum 33882080_f1_118 4180 20751 1479 492 138 −6 eastern European U70653 (sr:eastern european house mouse) (de:mus house mouse musculus musculus sex determining protein (sry) gene, completecds.) (nt:hmg box transcription factor) 31660418_f1_119 4181 20752 2250 749 142 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 31895631_f1_120 4182 20753 939 312 145 −10 Bacillus E69779 subtilis/Bacillus globigii 12380131_f1_124 4183 20754 459 152 127 −7 Volvox carteri S22697 16589541_f1_127 4184 20755 1362 453 112 −4 Klebsiella Contig509A GTC ORF with score 222 to: (ai:7000835409) pneumoniae (or:Enterobacter cloacae) 10213416_f1_130 4185 20756 792 263 130 −8 Staphylococcus CONTIG063 GTC ORF with score 130 to: (ai:7000770652) epidermidis C (or:Pseudomonas aeruginosa) 16285432_f1_137 4186 20757 2454 817 285 −24 Enterobacter cloacae CONTIG485 GTC ORF with score 285 to: (ai:7000770659) (or:Pseudomonas aeruginosa) 10630417_f1_152 4187 20758 537 178 90 −3 Aspergillus Contig4452 GTC ORF with score 90 to: (ai:7000770674) fumigatus (or:Pseudomonas aeruginosa) 4397088_f1_154 4188 20759 480 159 214 −17 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromaticivorans pn11, complete plasmidsequence.) (nt:similar to m. tuberculosis hypothetical protein) 35681691_f1_158 4189 20760 963 320 946 −95 Enterobacter cloacae CONTIG279 GTC ORF with score 946 to: (ai:7000770680) (or:Pseudomonas aeruginosa) 5987968_f1_159 4190 20761 1980 659 13161415_f1_165 4191 20762 375 124 144 −10 Enterobacter cloacae CONTIG485 GTC ORF with score 144 to: (ai:7000770687) (or:Pseudomonas aeruginosa) 31880406_f1_174 4192 20763 1248 415 729 −72 Cyanobacterium P74311 (sr:pcc 6803,) (de:hypothetical 42.4 kd protein synechocystis slr0944) 36510390_f1_208 4193 20764 972 323 113 −3 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b). 35284580_f1_223 4194 20765 264 87 3133532_f1_234 4195 20766 261 86 15645831_f1_242 4196 20767 1473 490 32319693_f1_247 4197 20768 552 183 105 −3 mice|C57BL/6xCBA/ P35550 (sr:,mouse) (de:fibrillarin (nucleolar protein CaJ hybrid 1)) 2593875_f1_260 4198 20769 1614 537 823 −82 Escherichia coli P36880 (de:hypothetical 28.5 kd protein in hpt-pand intergenic region) 31678817_(')f1_264 4199 20770 822 273 357 −33 Klebsiella Contig348A GTC ORF with score 357 to: (ai:7000770786) pneumoniae (or:Pseudomonas aeruginosa) 16902031_f1_267 4200 20771 1611 536 162 −8 Herpes simplex virus AF015297 (de:human herpesvirus 6 (strain uganda-1102) (type 6/strain ie2hom mrna, complete cds.) (nt:similar to the Uganda-1102) immediate-early 2 protein of human) 17005277_f1_270 4201 20772 735 244 402 −37 Salmonella U69493 (fn:probable repressor protein of gntr family) choleraesuis (de:salmonella typhimurium thij and orf1 serotype genes, partial cds, and phnx,phnw, phnr, phns, typhimurium phnt, phnu and phnv genes, complete cds.) 15645760_f1_280 4202 20773 516 171 281 −25 Acinetobacter CONTIG229 GTC ORF with score 281 to: (ai:7000770802) baumannii C (or:Pseudomonas aeruginosa) 29940777_f1_281 4203 20774 1278 425 102 −2 Pseudomonas putida Q59692 (de:cell division protein ftsz) 2521915_f1_286 4204 20775 1335 444 10650282_f1_292 4205 20776 618 205 92 −2 African clawed frog X96469 (sr:african clawed frog) (de:x.laevis mrna for c4sr protein.) (nt:c4 refers to the two 4xcys zinc fingers and sr to) 31460750_f1_303 4206 20777 1851 616 10631880_f2_309 4207 20778 609 202 124 −5 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 24508336_f1_310 4208 20779 369 122 16692918_f1_311 4209 20780 1038 345 738 −73 Escherichia coli P37327 (de:hypothetical 34.5 kd protein in vacj-argw intergenic region) 32714586_f1_313 4210 20781 498 165 7290638_f1_321 4211 20782 300 99 648527_f1_326 4212 20783 843 280 181 −14 Klebsiella Contig560A GTC ORF with score 274 to: (ai:7000846970) pneumoniae (or:Enterobacter cloacae) 31534830_f1_333 4213 20784 330 109 4970936_f1_335 4214 20785 330 109 25829833_f1_336 4215 20786 426 141 157 −11 Streptomyces AL023496 (de:streptomyces coelicolor cosmid 1a6.) coelicolor (nt:sc1a6.22, unknown; : 135 aa) 34119058_f1_338 4216 20787 1455 484 104 −2 Theileria annulata A45560 6538267_f1_340 4217 20788 318 105 94 −3 Indian corn D84507 (sr:zea mays (strain:inbred line h84) root cdna to mrna) (de:zea mays mrna for cdpk-related protein kinase, partial cds, clonezmcrk1.) (nt:does not require calcium for its activity (by) 25579186_f1_346 4218 20789 225 74 10627165_f2_351 4219 20790 1110 369 209 −14 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10658156_f2_356 4220 20791 882 293 366 −33 Escherichia coli P23860 (de:spermidine/putrescine transport system permease protein potb) 10672956_f2_357 4221 20792 837 278 547 −53 Escherichia coli P23859 (de:spermidine/putrescine transport system permease protein potc) 3402216_f2_366 4222 20793 1647 548 110 −3 Homo sapiens S10889 (cl:proline-rich protein) (sr:, man) 33487706_f2_393 4223 20794 489 162 293 −26 Klebsiella Contig413A GTC ORF with score 669 to: (ai:7000828461) pneumoniae (or:Enterobacter cloacae) 31500642_f2_396 4224 20795 1395 464 755 −75 Klebsiella Contig432A GTC ORF with score 755 to: (ai:7000770918) pneumoniae (or:Pseudomonas aeruginosa) 32552205_f2_399 4225 20796 405 134 112 −5 no gb taxonomy P28284 (sr:type 2 / hg52,) (de:trans-acting match transcriptional protein icp0 (vmw118 protein)) 25875832_f2_400 4226 20797 285 94 182 −14 Escherichia coli P31065 (de:hypothetical 8.6 kd protein in amya-flie intergenic region (orf 9)) 13099082_f2_401 4227 20798 822 273 149 −10 Klebsiella Contig413A GTC ORF with score 149 to: (ai:7000770923) pneumoniae (or:Pseudomonas aeruginosa) 24500880_f2_411 4228 20799 1317 438 1072836_f2_412 4229 20800 1203 400 453 −43 Enterobacter cloacae CONTIG465 GTC ORF with score 479 to: (ai:7501740727) (or:Klebsiella pneumoniae) 10942903_f2_417 4230 20801 366 121 316 −28 Enterobacter cloacae CONTIG465 GTC ORF with score 833 to: (ai:7501740713) (or:Klebsiella pneumoniae) 33683282_f2_425 4231 20802 702 233 467 −44 Enterobacter cloacae CONTIG465 GTC ORF with score 575 to: (ai:7501740732) (or:Klebsiella pneumoniae) 31651000_f2_429 4232 20803 465 154 132 −8 Enterobacter cloacae CONTIG465 GTC ORF with score 806 to: (ai:7501728546) (or:Klebsiella pneumoniae) 31805388_f2_432 4233 20804 1209 402 26062813_f2_437 4234 20805 471 156 158 −12 Klebsiella Contig092A GTC ORF with score 376 to: (ai:7000832355) pneumoniae (or:Enterobacter cloacae) 15867917_f2_438 4235 20806 627 208 102 −2 Strongyloccetrotus S23809 (cl:collagen alpha 2(i) chain:fibrillar collagen purpuratus carboxyl-terminal homology) (sr:, purple urchin) 14979200_f2_442 4236 20807 648 215 134 −9 Clostridium Contig107H GTC ORF with score 134 to: (ai:7000770964) acetobutylicum (or:Pseudomonas aeruginosa) 26756586_f2_452 4237 20808 2721 906 3787 −9999 Azotobacter P36223 (ec:2.7.7.59) (de:transferase) (uridylyl vinelandii removing enzyme)) 35723342_f2_467 4238 20809 603 200 117 −7 longfin squid S56117 (sr:, longfin squid) 10648958_f2_470 4239 20810 777 258 222 −18 Escherichia coli P76194 (de:hypothetical 15.8 kd protein in lpp-arod intergenic region) 31925456_f2_472 4240 20811 1377 458 16897567_f2_475 4241 20812 1179 392 157 −11 Klebsiella Contig525A GTC ORF with score 465 to: (ai:7000829263) pneumoniae (or:Enterobacter cloacae) 2605208_f2_477 4242 20813 480 159 103 −3 Plasmodium vivax U08977 (de:plasmodium vivax isolate ch-3 circumsporozoite protein gene,partial cds.) 16901026_f2_479 4243 20814 1389 462 154 −8 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 11854837_f2_480 4244 20815 411 136 169 −13 Escherichia coli P77717 (de:precursor) 33879167_f2_483 4245 20816 495 164 197 −16 Acinetobacter CONTIG213 GTC ORF with score 197 to: (ai:7000771005) baumannii C (or:Pseudomonas aeruginosa) 16931540_f2_487 4246 20817 660 219 273 −24 Acinetobacter CONTIG213 GTC ORF with score 273 to: (ai:7000771009) baumannii C (or:Pseudomonas aeruginosa) 7306456_f2_493 4247 20818 1425 474 7322575_f2_498 4248 20189 507 168 112 −4 Tetrahymena P40631 (de:proteins alpha, beta, delta and gamma) thermophila (mic 1h)) 17066701_f2_499 4249 20820 1164 387 223 −18 Klebsiella Contig452A GTC ORF with score 362 to: (ai:7000824095) pneumoniae (or:Enterobacter cloacae) 32697017_f2_515 4250 20821 2592 863 434 −40 Enterobacter cloacae CONTIG485 GTC ORF with score 434 to: (ai:7000771037) (or:Pseudomonas aeruginosa) 4738951_f2_516 4251 20822 477 158 123 −8 Enterobacter cloacae CONTIG485 GTC ORF with score 135 to: (ai:7000791152) (or:Pseudomonas aeruginosa) 16665793_f2_518 4252 20823 474 157 194 −15 Enterobacter cloacae CONTIG485 GTC ORF with score 242 to: (ai:7000791154) (or:Pseudomonas aeruginosa) 6492677_f2_521 4253 20824 1257 418 22548753_f2_527 4254 20825 1107 368 288 −25 Caenorhabditis Q09535 (de:hypothetical 48.0 kd protein f10b5.5 in elegans chromosome iii) 7321015_f2_530 4255 20826 1023 340 14349041_f2_532 4256 20827 642 213 136 −6 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6 u86, region ie-b) 31878331_f2_535 4257 20828 924 307 4891002_f2_537 4258 20829 1425 474 336 −31 Enterobacter cloacae CONTIG485 GTC ORF with score 336 to: (ai:7000771059) (or:Pseudomonas aeruginosa) 35211458_f2_540 4259 20830 987 328 146 −10 Enterobacter cloacae CONTIG485 GTC ORF with score 146 to: (ai:7000771062) (or:Pseudomonas aeruginosa) 16142058_f2_544 4260 20831 1278 425 412 −38 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 16509825_f2_546 4261 20832 621 206 507 −48 Escherichia coli P37311 (de:arsenate reductase (arsenical pump modifier)) 5204833_f2_587 4262 20833 1863 620 36330441_f2_604 4263 20834 924 307 171 −10 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 32555165_f2_608 4264 20835 909 302 16491430_f2_609 4265 20836 735 244 509 −49 Escherichia coli P75805 (de:hypothetical 23.9 kd protein in moea-dacc intergenic region) 29849158_f2_610 4266 20837 1008 335 1062 −107 Escherichia coli P36879 (de:hypothetical abc transporter atp-binding protein yadg) 16927333_f2_612 4267 20838 1428 475 225 −18 Klebsiella Contig348A GTC ORF with score 225 to: (ai:7000771134) pneumoniae (or:Pseudomonas aeruginosa) 16305205_f2_618 4268 20839 660 219 101 −5 Klebsiella Contig479A GTC ORF with score 101 to: (ai:7000771 140) pneumoniae (or:Pseudomonas aeruginosa) 36130055_f2_623 4269 20840 726 241 307 −27 Escherichia coli D90865 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna kohara clone #410(53.0-53.4 min.).) (nt:similar to (swissprot accession number p43262):) 23619031_f2_625 4270 20841 1188 395 292 −26 Escherichia coli P37055 (de:hnr protein) 14535465_f2_626 4271 20842 450 149 95 −5 Enterobacter cloacae CONTIG393 GTC ORF with score 95 to: (ai:7000771148) (or:Pseudomonas aeruginosa) 17067916_f2_628 4272 20843 1182 393 458 −44 Klebsiella Contig368A GTC ORF with score 459 to: (ai:7000841531) pneumoniae (or:Enterobacter cloacae) 35833588_f2_629 4273 20844 243 80 2589506_f2_635 4274 20845 540 179 144 −10 longfin squid S56117 (sr:, longfin squid) 10805458_f2_636 4275 20846 1593 530 166 −9 Human P16818 (sr:ad169,) (de:hypothetical protein ul61) cytomegalovirus 11730390_f2_645 4276 20847 474 157 114 −5 equine herpesvirus D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVR-1 (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 16848453_f2_646 4277 20848 747 248 130 −7 Acinetobacter CONTIG173 GTC ORF with score 161 to: (ai:59056) baumannii C (or:Alternaria alternata) 13011467_f2_648 4278 20849 1785 594 12932205_f2_653 4279 20850 720 239 17074040_f2_654 4280 20851 720 239 16895751_f2_659 4281 20852 531 176 115 −5 Achromobacter A61183 georgiopolitanum 10553817_f2_663 4282 20853 696 231 129 −5 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 7291638_f2_664 4283 20854 1020 339 271 −23 Escherichia coli F65017 29558527_f2_673 4284 20855 456 151 10953126_f2_676 4285 20856 510 169 535 −52 Acinetobacter CONTIG150 GTC ORF with score 535 to: (ai:7000771198) baumannii C (or:Pseudomonas aeruginosa) 68_f2_677 4286 20857 573 190 14186_f2_681 4287 20858 1050 349 221 −18 Escherichia coli B65049 259443_f3_683 4288 20859 849 282 156 −9 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3)) 31350343_f3_685 4289 20860 1074 357 218 −16 Archaeoglobus D69348 fulgidus 30192931_f3_687 4290 20861 1314 437 191 −15 Klebsiella Contig471A GTC ORF with score 306 to: (ai:7000774112) pneumoniae (or:Pseudomonas aeruginosa) 10005055_f3_689 4291 20862 255 84 98 −5 Aspergillus Contig7428 GTC ORF with score 217 to: (ai:5500691725) fumigatus (or:Santalum album) (sr:white sandalwood) (de:santalum album proline rich protein mrns, complete cds.) 4414811_f3_692 4292 20863 1074 357 525 −50 Escherichia coli P31133 (de:putrescine-binding periplasmic protein precursor) 35804178_f3_696 4293 20864 495 164 155 −10 Rattus norvegicus P02454 (sr:,rat) (de:collagen alpha 1(i) chain (fragments)) 13141387_f3_698 4294 20865 1878 625 550 −53 Vibrio cholerae AB012956 (sr:vibrio cholerae (str:mo45) dna) (de:vibrio cholerae genes for 0-antigen synthese, strain mo45,complete cds.) (nt:unknown) 26421917_f3_701 4295 20866 1242 413 747 −74 Klebsiella Contig366A GTC ORF with score 773 to: (ai:7000818022) pneumoniae (or:Enterobacter cloacae) 12360381_f3_702 4296 20867 3924 1307 3846 −9999 Azotobacter P27345 (de:dna mismatch repair protein muts) vinelandii 509687_f3_703 4297 20868 327 108 570 −55 Azotobacter A29936 (pn:ferredoxin (3fe-4s)(4fe-4s):ferredoxin i) vinelandii (cl:ferredoxin 2(4fe-4s):ferredoxin 2(4fe-4s) homology) 11031268_f3_705 4298 20869 420 139 168 −13 Klebsiella Contig485A GTC ORF with score 168 to: (ai:7000771227) pneumoniae (or:Pseudomonas aeruginosa) 11955152_f3_713 4299 20870 1686 561 238 −19 Klebsiella Contig413A GTC ORF with score 502 to: (ai:7000828491) pneumoniae (or:Enterobacter cloacae) 4792556_f3_714 4300 20871 999 332 378 −35 Klebseilla Contig523A GTC ORF with score 378 to: (ai:7000771236) pneumoniae (or:Pseudomonas aeruginosa) 10427276_f3_715 4301 20872 201 66 275 −24 Klebsiella Contig432A GTC ORF with score 275 to: (ai:7000771237) pneumoniae (or:Pseudomonas aeruginosa) 1065655_f3_716 4302 20873 318 105 97 −4 equine herpesvirus M86664 (sr:equine herpesvirus type 1 (strain ab4p) type 1 EVH-1 dna) (de:equine herpesvirus 1 complete genome.) (nt:orf 35.5) 14886667_f3_717 4303 20874 1311 436 108 −3 mice|C57BL/6xCBA/ AF071186 (sr:house mouse) (de:mus musculus ww CaJ hybrid domain binding protein 11 mrna, complete cds.) (nt:wbp11) 1433132_f3_718 4303 20875 1242 413 98 −1 Homo sapiens AF055989 (sr:human) (de:homo sapiens shaw type potassium channel kv3.3 (kcnc3) mrna,complete cds.) 4162906_f3_724 4305 20876 1722 573 522 −50 Klebsiella Contig479A GTC ORF with score 932 to: (ai:7000830881) pneumoniae (or:Enterobacter cloaecae) 10414833_726 4306 20877 441 146 106 −4 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 21925408_f3_734 4307 20878 1023 340 274 −24 Enterobacter cloacae CONTIG465 GTC ORF with score 211 to: (ai:7000771256) (or:Pseudomonas aeruginosa) 22144155_f3_735 4308 20879 969 322 227 −18 Enterobacter cloacae CONTIG465 GTC ORF with score 806 to: (ai:7501728546) (or:Klebsiella pneumoniae) 33879518_f3_736 4309 20880 1128 375 264 −23 Enterobacter cloacae CONTIG465 GTC ORF with score 567 to: (ai:7501727589) (or:Klebsiella pneumoniae) 17050206_f3_740 4310 20881 618 205 131 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 4319792_f3_742 4311 20882 1461 486 405 −38 Klebsiella Contig144A GTC ORF with score 405 to: (ai:7000771264) pneumoniae (or:Pseudomonas aeruginosa) 1454430_f3_745 4312 20883 696 231 335 −30 Klebsiella Contig120A GTC ORF with score 504 to: (ai:7000832363) pneumoniae (or:Enterobacter cloacae) 31932091_f3_746 4313 20884 1359 452 384 −36 Enterobacter cloacae CONTIG465 GTC ORF with score 925 to: (ai:7501727205) (or:Klebsiella pneumoniae) 22769408_f3_747 4314 20885 1176 391 108 −4 mice|C57Bl/6xCBA/ U46463 (sr:house mouse) (de:mus musculus glutamine CaJ hybrid repeat protein-1 mrna, complete cds.) (nt:grp- 1) 10257055_f3_748 4315 20886 489 162 133 −8 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 12594431_f3_750 4316 20887 282 93 101 −6 Aspergillus Contig8078 GTC ORF with score 219 to: (ai:175260) fumigatus (or:Volvox carteri) 24813132_f3_751 4317 20888 2865 954 422 −39 Enterobacter cloacae CONTIG501 GTC ORF with score 516 to: (ai:7501763548) (or:Klebsiella pneumoniae) 15051966_f3_752 4318 20889 474 157 33445215_f3_753 4319 20890 393 130 13072533_f3_754 4320 20891 2553 850 713 −72 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 52/162.) (nt:rv1201c, (mtci364.13c), len: 317. highly similar) 22738206_f3_755 4321 20892 1230 409 105 −5 longfin squid S56117 (sr:, longfin squid) 10393792_f3_762 4322 20893 1098 365 99 −1 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene,complete cds.) (nt:herpesvirus saimiri orf73 homolog) 32432288_f3_765 4323 20894 2598 865 1479 −151 Escherichia coli P00482 (ec:2.3.1.15) (de:glycerol-3-phosphate acyltransferase,) 16916287_f3_766 4324 20895 873 290 3255157_f3_772 4325 20896 327 108 120 −8 Acinetobacter CONTIG213 GTC ORF with score 120 to: (ai:7000771294) baumannii C (or:Pseudomonas aeruginosa) 35785277_f3_779 4326 20897 603 200 138 −10 Klebsiella Contig378A GTC ORF with score 378 to: (ai:7000829982) pneumoniae (or:Enterobacter cloacae) 25829533_f3_780 4327 20898 525 174 230 −19 Klebsiella Contig462A GTC ORF with score 230 to: (ai:7000771302) pneumoniae (or:Pseudomonas aeruginosa) 31899062_f3_786 4328 20899 747 248 396 −37 Klebsiella Contig487A GTC ORF with score 878 to: (ai:7000827902) pneumoniae (or:Enterohacter cloacae) 14086006_f3_788 4329 20900 786 261 243 −20 Bordetella pertussis S66937 (de:orf1 . . . orf3 {transposon-like sequence} (bordetella pertussis,genomic, 3 genes, 2300 nt).) 2784758_f3_793 4330 20901 489 162 159 −12 Enterobacter cloacae CONTIG485 GTC ORF with score 159 to: (ai:7000771315) (or:Pseudomonas aeruginosa) 10816653_f3_803 4331 20902 591 196 116 −4 Saccharomyces P47033 (sr:,baker's yeast) (de:hypothetical 89.2 kd cerevisiae protein in scp160-smc3 intergenic region) 16802282_f3_808 4332 20903 468 155 93 −4 Aspergillus v1x1c353.x GTC ORF with score 458 to: (ai:307212) fumigatus (or:Volvox carteri) (de:v.carteri mrna for pherophorin-s.) 32478792_f3_809 4333 20904 1098 365 161 −11 Enterobacter cloacae CONTIG485 GTC ORF with score 161 to: (ai:7000771331) (or:Pseudomonas aeruginosa) 35364808_f3_814 4334 20905 630 209 275 −24 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromaticivorans pn11, complete plasmidsequence.) (nt:similar to m. tuberculosis hypothetical protein) 34242040_f3_817 4335 20906 714 237 13017191_f3_825 4336 20907 627 208 101 −3 Gallus gallus Y14166 (sr:chicken) (de:gallus gallus mrna for domesticus attachment region binding protein (arbp).) 16485080_f3_826 4337 20908 411 136 98 −3 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 25406428_f3_827 4338 20909 672 223 153 −10 Enterobacter cloacae CONTIG485 GTC ORF with score 153 to: (ai:7000771349) (or:Pseudomonas aeruginosa) 16213333_f3_832 4339 20910 657 218 142 −10 Enterobacter cloacae CONTIG485 GTC ORF with score 142 to: (ai:7000771354) (or:Pseudomonas aeruginosa) 19696950_f1_837 4340 20911 339 112 166 −12 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 30156705_f3_841 4341 20912 894 297 812 −81 Yersinia U58366 (fn:unknown) (de:yersinia enterocolitica enterocolitica tn2502 transposon defective transposase(tnpa), resolvase (tnpr), arsenate reductase (arsc), transmembraneprotein of arsenite pump (arsb), arsenite inducible repressor(arsr), and arsh (arsh) genes, . . . 35835017_f3_842 4342 20913 1257 418 14073336_f3_845 4343 20914 1209 402 12974031_f3_851 4344 20915 414 137 92 −3 Aspergillus Contig9386 GTC ORF with score 418 to: (ai:7000707423) fumigatus (or:Haliotis rufescens) (sr:california red abalone) (de:haliotis rufescens lustrin a mrna, complete cds.) (nt:extracellular matrix protein; modular structure) 29969536_f3_866 4345 20916 1965 654 7305181_f3_867 4346 20917 2493 830 327 −27 Klebsiella Contig559A GTC ORF with score 1075 to: pneumoniae (ai:7000840697) (or:Enterobacter cloacae) 30488566_f3_873 4347 20918 1311 436 16900767_f3_876 4348 20919 420 139 101 −3 Alphaherpesvirus P33485 (sr:kaplan,prv) (de:probable nuclear antigen) pseudorabies virus PRV 3175391_f3_881 4349 20920 192 63 5291588_f3_882 4350 20921 510 169 201 −16 Enterococcus CONTIG498 GTC ORF with score 201 to: (ai:7000771404) faecium C (or:Pseudomonas aeruginosa) 25573501_f3_898 4351 20922 2571 856 471 −44 Klebsiella Contig343A GTC ORF with score 518 to: (ai:7000814935) pneumoniae (or:Enterobacter cloacae) 23728555_f3_912 4352 20923 261 86 2007080_f3_913 4353 20924 789 262 13145692_f3_914 4354 20925 927 308 716 −71 Escherichia coli Q46920 (de:hypothetical 32.6 kd protein in syd-sdac intergenic region) 13869092_f3_929 4355 20926 1320 439 5203387_f3_931 4356 20927 1788 595 26698543_f3_932 4357 20928 360 119 26845905_f3_937 4358 20929 1614 537 525 −50 Pseudomonas D50642 (sr:pseudomonas aeruginosa (strain:pao1) dna) aeruginosa (de:pseudomonas aeruginosa pcta gene for transducer, complete cds.) (nt:chemotaxis system) 839150_f3_938 4359 20930 1245 414 92 −2 Aspergillus Contig8591 GTC ORF with score 247 to: (ai:405746) fumigatus (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:mcthod: conceptual translation supplied by author.) 3384400_f3_951 4360 20931 837 278 34386566_f3_956 4361 20932 1449 482 632 −62 Klebsiella Contig532A GTC ORF with score 632 to: (ai:7000771478) pneumoniae (or:Pseudomonas aeruginosa) 26261281_f3_961 4362 20933 492 163 125 −7 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) dna) georgiopolitanum (de:pseudomonas sp. (strain imt37) monooxygenase subunit gene, completecds.) 13072893_f3_964 4363 20934 813 270 375 −34 Syncchococcus sp. U59236 (de:synechococcus pcc7942 ribosomal protein (strain PCC 7942) s1 of 30s ribosome (rps 1) org271 orf231, orf341, carboxyltransferase alpha subunit (acca),orf245, orf227, and gtp cyclohydrolase i (fole) genes, completecds, and orf205 gene, partial cds.) (nt . . . 33867655_f3_965 4364 20935 432 143 141 −10 Methanobacterium G69041 thermo- autotrophicum 35441682_f3_967 4365 20936 537 178 92 −2 Mycobacterium AF002133 (de:mycobacterium avium strain gir10 avium transcriptional regulator (mav81)gene, partial cds, aconitase (acn), invasin 1 (inv 1), invasin 2(inv2), transcriptional regulator (moxr), ketoacyl-reductase(fabg), enoyl-reductase (inha) and ferro . . . 2204566_f3_969 4366 20937 615 204 126 −6 Streptomyces AB000385 (sr:streptomyces coelicolor (sub_spec:a3, coelicolor str:m130) dna) (de:streptomyces coelicolor gene for cprb, complete cds.) 31380041_f3_971 4367 20938 471 156 107 −4 Drosophila Q05319 (sr:,fruit fly) (ec:3.4.21.—) (de:serine proteinase melanogaster stubble, (stubble-stubbloid protein)) 29822557_f3_984 4368 20939 537 178 221 −18 Klebsiella Contig353A GTC ORF with score 221 to: (ai:7000771506) pneumoniae (or:Pseudomonas aeruginosa) 15646007_c1_994 4369 20940 357 118 14307026_c1_1001 4370 20941 1350 449 2217 −230 Pseudomonas AB006797 (sr:pseudomonas aeruginosa (strain:pao1) dna) aeruginosa (de:pseudomonas aeruginosa oprq gene for opre3, complete cds.) 32442205_c1_1002 4371 20942 528 175 20050411_c1_1007 4372 20943 834 277 448 −42 Enterobacter cloacae CONTIG511 GTC ORF with score 448 to: (ai:7000771529) (or:Pseudomonas aeruginosa) 16270143_c1_1013 4373 20944 555 184 114 −5 Homo sapiens P10162 (sr:,human) (de:(fragment)) 31844566_c1_1014 4374 20945 531 176 29555166_c1_1017 4375 20946 300 99 103 −4 Alphaherpesvirus P33479 (sr:kaplan,prv) (de:immediate-early protein pseudorabies virus ic180) PRV 4869537_c1_1019 4376 20947 888 295 115 −4 African clawed frog S07498 (cl:dermal gland protein apeg:trefoil homology) (sr:, african clawed frog) 16895762_c1_1022 4377 20948 222 73 13019783_c1_1024 4378 20949 417 138 125 −6 Homo sapiens M94131 (sr:homo sapiens intestine cdna to mrna) (de:human mucin 2 (muc2) mrna, partial cds.) 7241562_c1_1026 4379 20950 546 181 95 −5 longfin squid S56117 (sr:, longfin squid) 22552280_c1_1028 4380 20951 1776 591 276 −23 Klebsiella Contig522A GTC ORF with score 276 to: (ai:7000771550) pneumoniae (or:Pseudomonas aeruginosa) 34393818_c1_1031 4381 20952 420 139 187 −15 Klebsiella Contig527A GTC ORF with score 187 to: (ai:7000771553) pneumoniae (or:Pseudomonas aeruginosa) 9819775_c1_1033 4382 20953 513 170 32160191_c1_1035 4383 20954 1950 649 26648268_c1_1040 4384 20955 1374 457 115 −6 Klebsiella Contig411A GTC ORF with score 115 to: (ai:7000771562) pneumoniae (or:Pseudomonas aeruginosa) 32525642_c1_1043 4385 20956 477 158 123 −7 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 16489512_c1_1046 4386 20957 537 178 16198961_c1_1048 4387 20958 1320 439 16195187_c1_1050 4388 20959 267 88 12782215_c1_1052 4389 20960 273 90 187 −15 Enterobacter cloacae CONTIG501 GTC ORF with score 187 to: (ai:7000771574) (or:Pseudomonas aeruginosa) 16036061_c1_1054 4390 20961 936 311 920 −92 Escherichia coli S40535 (ec:2.2.1.2) 14708156_c1_1062 4391 20962 1203 400 24652316_c1_1069 4392 20963 693 230 813 −81 Pseudomonas Q02540 (sr:,pvtomato) (de:transcriptional activator syringae protein copr) 14730083_c1_1071 4393 20964 1239 412 354 −33 Enterobacter cloacae CONTIG503 GTC ORF with score 115 to: (ai:73282) (or:Dictyostelium discoideum) (sr:,slime mold) (de:g-box hinding factor (gbf)) 7269831_c1_1073 4394 20965 273 90 99 −5 Klebsiella Contig556A GTC ORF with score 173 to: (ai:7000763498) pneumoniae (or:Pseudomonas aeruginosa) 35258341_c1_1077 4395 20966 1746 581 196 −15 Klebsiella Contig343A GTC ORF with score 196 to: (ai:7000771599) pneumoniae (or:Pseudomonas aeruginosa) 36229016_c1_1078 4396 20967 588 195 180 −13 Pseudomonas M57551 (sr:p.aeruginosa (strain 8830) dna) aeruginosa (de:p.aeruginosa transcription regulatory protein (algp) gene, completecds.) (nt:putative) 10275930_c1_1082 4397 20968 801 266 109 −4 pig roundworm A44982 (cl:unassigned collagens) (sr:, pig roundworm) 29973281_c1_1083 4398 20969 3105 1034 97 −1 Caenorhabditis Z36948 (de:caenorhabditis elegans cosmid d2089, elegans complete sequence.) (nt:contains a valine and arginine rich domain,) 26645662_c1_1084 4399 20970 876 291 25895788_c1_1085 4400 20971 471 156 201 −16 Caedibacter U04523 (de:caedibacter taeniospiralis 116 r body taeniospiralis synthesis and assembly (rebarebb, rebc, rebd) genes, complete cds.) 29533307_c1_1093 4401 20972 597 198 32213131_c1_1097 4402 20973 810 269 127 −5 blue mussel AF043944 (sr:blue mussel) (de:mytilus edulis nongradient byssal precursor, mrna, complele cds.) (nt:precol-ng) 35180467_c1_1102 4403 20974 492 163 109 −3 Alphaherpesvirus B40505 pseudorabies virus PRV 12361007_c1_1104 4404 20975 624 207 105 −6 Enterobacter cloacae CONTIG498 GTC ORF with score 105 to: (ai:7000771626) (or:Pseudomonas aeruginosa) 31681942_c1_1125 4405 20976 573 190 102 −2 Caenorhabditis U41538 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid r04e5.) (nt:proline rich; coded for by c. elegans cdna) 31292537_c1_1130 4406 20977 558 185 184 −14 Plasmid pKM101 U72482 (fn:prevention of disadvantage of reca protein) (de:plasmid pkm 101 resolvase (uvp1), repa (repa), metalloproteinase(ardk), mucab proteins (mucab), antirestriction protein (ardb),ardr (ardr), ccgd (ccgd), ccgc (ccgc), arda (arda). ccgai ( . . . 24619417_c1_1132 4407 20978 219 72 26753407_c1_1138 4408 20979 324 107 22929158_c1_1143 4409 20980 1818 605 2139 −221 Escherichia coli AB011549 (sr:escherichia coli (str:o157:h7, sub_str:rimd 0509952) (de:escherichia coli plasmid po157 dna, complete sequence.) (nt:putative reverse transcriptase; similar to) 16911456_c1_1155 4410 20981 771 256 12292331_c1_1156 4411 20982 738 245 393 −37 Enterobacter cloacae CONTIG485 GTC ORF with score 432 to: (ai:7000789601) (or:Pseudomonas aeruginosa) 20800826_c1_1157 4412 20983 408 135 123 −7 Myxococcus xanthus AF055904 (de:myxococcus xanthus acetylornithine deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 13930290_c1_1160 4413 20984 390 129 134 −9 Enterobacter cloacae CONTIG485 GTC ORF with score 134 to: (ai:7000771682) (or:Pseudomonas aeruginosa) 32447886_c1_1169 4414 20985 1800 599 33492667_c1_1174 4415 20986 183 60 12754212_c1_1177 4416 20987 783 260 167 −13 Enterobacter cloacae CONTIG485 GTC ORF with score 173 to: (ai:7000789947) (or:Pseudomonas aeruginosa) 13150805_c1_1183 4417 20988 747 248 360 −33 Enterobacter cloacae CONTIG485 GTC ORF with score 360 to: (ai:7000771705) (or:Pseudomonas aeruginosa) 2525340_c1_1190 4418 20989 576 191 349 −32 Escherichia coli Q47685 (de:hypothetical 18.1 kd protein in proa-perr intergenic region) 33864833_c1_1192 4419 20990 1161 386 783 −78 Enterobacter cloacae CONTIG485 GTC ORF with score 783 to: (ai:7000771714) (or:Pseudomonas aeruginosa) 5191643_c1_1193 4420 20991 1404 467 869 −87 Enterobacter cloacae CONTIG485 GTC ORF with score 869 to: (ai:7000771715) (or:Pseudomonas aeruginosa) 14942558_c1_1199 4421 20992 510 169 238 −20 Bordetella pertussis S66937 (de:orf1 . . . orf3 {transposon-like sequence} (bordetella pertussis,genomic, 3 genes, 2300 nt).) 16218881_c1_1201 4422 20993 306 101 210 −16 Escherichia coli P00864 (ec:4.1.1.31) (de:phosphoenolpyruvate carboxylase, (pepcase) (pepc)) 36464093_c1_1202 4423 20994 1002 333 142 −9 mice|C57BL/6xCBA/ Q06666 (sr:,mouse) (de:octapeptide-repeat protein t2) CaJ hybrid 29817655_c1_1203 4424 20995 609 202 109 −6 Aspergillus Contig8670 GTC ORF with score 157 to: (ai:112661) fumigatus (or:Saccharomyces cerevisiae) (gtcfc:11.1:5.3) (keggfc:14.2) (sgdfc:9.1.0) (db:gtc- saccharomyces cerevisiae) 2616450_c1_1204 4425 20996 402 133 29781708_c1_1205 4426 20997 885 294 521 −50 Escherichia coli P37348 (de:hypothetical 31.5 kd protein in asps-bisz intergenic region) 10417708_c1_1206 4427 20998 897 298 278 −24 Saccharopolyspora U82823 (de:saccharopolyspora erythraea putative erythraea carboxypeptidase, putativelysozyme, putative streptomyces subtilisin inhibitor-like protein,putative peptidyl-prolyl cis-trans isomerase, putative transposase,putative esterase mutated and put . . . 16269792_c1_1209 4428 20999 1416 471 252 −19 Arabidopsis thaliana AL021636 (sr:thale cress) (de:arabidopsis thaliana dna chromosome 4, bac clone f10n7 (essaiiproject).) (nt:strong similarity to flavonoid 3′, 5′-hydroxylase, 13151912_c1_1214 4429 21000 3102 1033 865 −88 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 29939515_c1_1225 4430 21001 495 164 106 −3 human herpesvirus U92288 (fn:helicase, helicase-primase complex) type 6 HHV-6 (de:human herpesvirus 6 serotype b putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 31892283_c1_1230 4431 21002 1068 355 105 −2 Pinctada fucata D86074 (sr:pinetada fucata cdna to mrna) (de:pinctada fucata mrna for insoluble protein, complete cds.) 15667932_c1_1232 4432 21003 1071 356 109 −3 Araneus diadematus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, partial cds.) 25891451_c1_1235 4433 21004 1233 410 12760168_c1_1237 4434 21005 1599 532 10056341_c1_1243 4435 21006 963 320 535 −52 Klebsiella Contig443A GTC ORF with score 884 to: (ai:7000832511) pneumoniae (or:Enterobacter cloacae) 2160331_cl_1244 4436 21007 939 312 1160 −118 Pseudomonas AB010087 (sr:pseudomonas aeruginosa (str:pao1) dna) aeruginosa (de:pseudomonas aeruginosa rpsb, tsf, pyrh, frr genes for ribosomalprotein s2, elongation factor ts, ump kinase, ribosome recyclingfactor, complete cds.) 11020943_c1_1246 4437 21008 561 186 137 10 Aspergillus Contig8591 GTC ORF with score 243 to: (ai:405746) fumigatus (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 9845207_c1_1248 4438 21009 459 152 96 −3 Pseudomonas AB010087 (sr:pseudomonas aeruginosa (str:pao1) dna) aeruginosa (de:pseudomonas aeruginosa rpsb, tsf, pyrh, frr genes for ribosomalprotein s2, elongation factor ts, ump kinase, ribosome recyclingfactor, complete cds.) 15804806_c1_1249 4439 21010 660 219 904 −90 Pseudomonas AB010087 (sr:pseudomonas aeruginosa (str:pao1) dna) aeruginosa (de:pseudomonas aeruginosa rpsb, tsf, pyrh, frr genes for ribosomalprotein s2, elongation factor ts, ump kinase, ribosome recyclingfactor, complete cds.) 25527043_c1_1250 4440 21011 771 256 667 −65 Escherichia coli Q47675 (de:hypothetical 18.8 kd protein in frr-cdsa intergenic region) 12938543_c1_1253 4441 21012 432 143 98 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 33441028_c1_1257 4442 21013 2466 821 1526 −156 Escherichia coll P39170 (de:unknown protein from 2d-page precursor (spots m621m63/o3/o9/t35)) 31876042_c1_1262 4443 21014 963 320 663 −65 Escherichia coli B28390 (de:ribonuclease h (ec 3.1.26.4) ii - escherichia coli) 16101436_c1_1263 4444 21015 1452 483 1259 −128 Escherichia coli P30143 (de:hypothetical 51.7 kd protein in thrc-talb intergenic region (orf8)) 658157_c1_1264 4445 21016 3597 1198 3478 −9999 Salmonella P14567 (ec:2.7.7.7) (de:dna polymerase iii, alpha choleraesuis chain,) serotype typhimurium 16588568_c1_1266 4446 21017 858 285 91 −1 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31426392_c1_1270 4447 21018 705 234 112 −5 Aspergiilus Contig8640 GTC ORF with score 97 to: (ai:7501000479) fumigatus (or:Homo sapiens) (sr:human) (de:homo sapiens synapsin iiia mrna, complete cds.) (nt:synaptic vesicle protein) 16116465_c1_1271 4448 21019 909 302 1031 −104 Escherichia coli P17579 (ec:4.1.2.16) (de:8-phosphate synthetase) (kdo 8-p synthase)) 15016380_c1_1272 4449 21020 1335 444 1683 −173 Escherichia coli G65059 (cl:enolase) (ec:4.2.1.11) (mp:60 min) 15676086_c1_1277 4450 21021 1128 375 134 −6 Bos primigenius AF025664 (pn:na-ca+k exchanger) (de:bos taurus na-ca+k taurus exchanger (bosnckx) mrna, partial cds.) (nt:ion exchanger; cytosolic region; expressed in) 32244216_c1_1278 4451 21022 996 331 153 −9 Enterobacter cloacae CONTIG512 GTC ORF with score 532 to: (ai:7501734693) (or:Klebsiella pneumoniae) 12750762_c1_1288 4452 21023 789 262 590 −57 Escherichia coli P36664 (de:survival protein sure) 486518_c1_1298 4453 21024 543 180 606 −59 Pseudomonas putida P72227 (de:hypothetical 16.7 kd protein in reca 5′region) 32520316_c1_1301 4454 21025 309 102 90 −4 Homo sapiens D38355 (cl:proline-rich protein) (sr:, man) 31914541_c1_1302 4455 21026 483 160 741 −73 Pseudomonas P37860 (de:regulatory protein recx) aeruginosa 16495915_c1_1306 4456 21027 2472 823 295 −22 Schizo- AL031786 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c24c6.) (nt:spbc24c6.09c, :825, pombe similarity:synechocystis) 35598777_c1_1309 4457 21028 591 196 207 −17 Enterobacterr cloacae CONTIG399 GTC ORF with score 115 to: (ai:58918) (or:Saccharomyces cerevisiae) (mp:14r) 24510205_c1_1311 4458 21029 1302 433 321 −29 Klebsiella Contig508A GTC ORF with score 727 to: (ai:7000827245) pneumoniae (or:Enterobacter cloacae) 25628918_c1_1312 4459 21030 873 290 528 −51 Escherichia coli Q47319 (de:hypothetical 27.0 kd protein in ung-pssa intergenic region) 6457063_c1_1316 4460 21031 381 126 266 −23 Haemophilus P44424 (ec:2.7.1.107) (de:(dgk)) influenzae 34630312_c1_1317 4461 21032 1653 550 181 −10 Klebsiella Contig467A GTC ORF with score 1506 to: pneumoniae (ai:7000829086) (or:Enterobacter cloacae) 12308406_c2_1318 4462 21033 765 254 100 −2 Homo sapiens P17542 (sr:,human) (de:acute lymphocytic leukemia-1 protein) (tal-1)) 2379053_c2_1319 4463 21034 357 118 140 −10 Escherichia coli P42617 (de:hypothetical 11.1 kd protein in exur-tdcc intergenic region) 32526042_c2_1321 4464 21035 351 116 117 −7 Acinetobacter CONTIG149 GTC ORF with score 117 to: (ai:7000771843) baumannii C (or:Pseudomonas aeruginosa) 12975817_c2_1322 4465 21036 642 213 452 −43 Escherichia coli U00008 (sr:escherichia coli k12 bhb2600) (de:centisome 49 region of e.coli k12 bhb2600.) (nt:dna repair protein.) 20157838_c2_1325 4466 21037 984 327 121 −5 Aspergillus Contig9951 GTC ORF with score 121 to: (ai:7000771847) fumigatus (or:Pseudomonas aeruginosa) 4814658_c2_1330 4467 21038 423 140 129 −7 no gb taxonomy JW0067 match 840_c2_1333 4468 21039 228 75 10556916_c2_1339 4469 21040 996 331 315 −28 Archaeoglobus C69370 fulgidus 22471961_c2_1340 4470 21041 1428 475 211 −17 Klebsiella Contig475A GTC ORF with score 247 to: (ai:7000838514) pneumoniae (or:Enterobacter cloacae) 33680430_c2_1341 4471 21042 1038 345 581 −56 Cyanobacterium S77453 (sr:pcc 6803, , pcc 6803) (sr:pcc 6803, ) syncchocystis 207331_c2_1346 4472 21043 1347 448 1494 −153 Escherichia coli P37906 (ec:1.—.—.—) (de:probable oxidoreductase ordl,) 24110041_c2_1356 4473 21044 432 143 24880032_c2_1361 4474 21045 279 92 100 −4 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14103382_c2_1362 4475 21046 849 282 197 −16 Bacillus C69931 subtilis/ Bacillus globigii 16307086_c2_1363 4476 21047 582 193 130 −6 Cyano- S76731 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 23885881_c2_1364 4477 21048 1305 434 749 −74 Achromobacter P06621 (sr:rs-16,) (cc:3.4.17.11) georgio- (de:(pteroylmonoglutamic acid hydrolase g2) politanum (glutamate carboxypeptidase)) 12367666_c2_1365 4478 21049 1581 526 179 −11 Enterobacter CONTIG479 GTC ORF with score 273 to: (ai:7000797020) cloacae (or:Pseudomonas aeruginosa) 36072007_c2_1366 4479 21050 1137 378 20581527_c2_1375 4480 21051 219 72 36142701_c2_1377 4481 21052 654 217 111 −4 Homo sapiens U82987 (sr:human) (dc:human bc1-2 binding component 3 (bbc3) mrna, partial cds.) (nt:bbc3; approximately 500 base pairs missing from 5′ 26192883_c2_1389 4482 21053 777 258 155 −9 Pseudomonas U45309 (de:pseudomonas aeruginosa 2- aeruginosa phosphonoacetaldehyde hydrolase gene,complete cds.) (nt:phosphonatase) 9844666_c2_1391 4483 21054 411 136 31875957_c2_1392 4484 21055 813 270 342 −31 Klebsiella Contig479A GTC ORF with score 342 to: (ai:7000771914) pneumoniae (or:Pseudomonas aeruginosa) 13151008_c2_1397 4485 21056 963 320 140 −7 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 36036537_c2_1402 4486 21057 795 264 95 −4 Klebsiella Contig523A GTC ORF with score 95 to: (ai:7000771924) pneumoniae (or:Pseudomonas aeruginosa) 16227008_c2_1405 4487 21058 2997 998 2000 −207 Escherichia F64746 coli 16901912_c2_1406 4488 21059 564 187 145 −9 Beta vulgaris S51939 (sr:,beet) (ec:3.2.1.14) 29775761_c2_1408 4489 21060 1137 378 116 −5 Escherichia P23484 (de:probable rna polymerase sigma factor feci) coli 31526061_c2_1409 4490 21061 312 103 158 −11 Caedibacter U04523 (de:caedibacter taeniospiralis 116 r body taeniospiralis synthesis and assembly (rebarebb, rebc, rebd) genes, complete cds.) 30682655_c2_1410 4491 21062 651 216 32549028_c2_1416 4492 21063 384 127 25901068_c2_1417 4493 21064 468 155 10585208_c2_1423 4494 21065 966 321 21908337_c2_1427 4495 21066 462 153 2204558_c2_1430 4496 21067 1134 377 299 −27 Enterobacter CONTIG327 GTC ORF with score 318 to: (ai:7501732075) cloacae (or:Klebsiella pneumoniae) 6384658_c2_1431 4497 21068 1236 411 320 −29 Enterobacter CONTIG327 GTC ORF with score 341 to: (ai:7000789506) cloacae (or:Pseudomonas aeruginosa) 29942915_c2_1434 4498 21069 588 195 34275932_c2_1437 4499 21070 2037 678 1136 −115 Escherichia P14294 (ec:5.99.1.2) (dc:dna topoisomerase iii,) coli 36430191_c2_1439 4500 21071 1755 584 174 −10 Bacteriophage P00476 (ec:2.1.1.73) (de:methyltransferase bsu spri) SPR (m.spri)) 32541515_c2_1440 4501 21072 801 266 14331650_c2_1441 4502 21073 408 135 34617155_c2_1442 4503 21074 414 137 22522066_c2_1446 4504 21075 1221 406 16878916_c2_1447 4505 21076 477 158 35739792_c2_1448 4506 21077 654 217 35820843_c2_1453 4507 21078 738 245 96 −1 crab-eating S55059 (cl:disintegrin homology) (sr:, crab-eating macaque macaque) 31268753_c2_1455 4508 21079 501 166 14972756_c2_1456 4509 21080 837 278 36116411_c2_1459 4510 21081 531 176 26816530_c2_1461 4511 21082 1272 423 26817542_c2_1462 4512 21083 231 76 16042667_c2_1465 4513 21084 1353 450 111 −2 Homo sapiens O14646 (sr:,human) (de:chromodomain-helicase-dna- binding protein 1 (chd-1)) 31895831_c2_1471 4514 21085 633 210 282 −25 Enterobacter CONTIG485 GTC ORF with score 434 to: (ai:7000790228) cloacae (or:Pseudomonas aeruginosa) 35347957_c2_1476 4515 21086 1155 384 332 −30 Enterobacter CONTIG485 GTC ORF with score 332 to: (ai:7000771998) cloacae (or: Pseudomonas aeruginosa) 16110752_c2_1480 4516 21087 423 140 179 −14 Klebsiella Contig434A GTC ORF with score 181 to: (ai:7000790268) pneumoniae (or:Pseudomonas aeruginosa) 35673517_c2_1481 4517 21088 951 316 478 −46 Enterobacter CONTIG485 GTC ORF with score 478 to: (ai:7000772003) cloacae (or:Pseudomonas aeruginosa) 32552256_c2_1494 4518 21089 375 124 13164131_c2_1495 4519 21090 378 125 130 −9 Enterobacter CONTIG485 GTC ORF with score 145 to: (ai:7000789613) cloacae (or:Pseudomonas aeruginosa) 3228926_c2_1498 4520 21091 1263 420 591 −58 Enterobacter CONTIG485 GTC ORF with score 591 to: (ai:7000772020) cloacae (or:Pseudomonas aeruginosa) 26430382_c2_1504 4521 21092 1542 513 32291683_c2_1505 4522 21093 909 302 93 −4 Klebsiella Contig483A GTC ORF with score 93 to: (ai:7000772027) pneumoniae (or:Pseudomonas aeruginosa) 35625930_c2_1509 4523 21094 468 155 191 −15 Enterobacter CONTIG485 GTC ORF with score 204 to: (ai:7000789631) cloacae (or:Pseudomonas aeruginosa) 12367693_c2_1515 4524 21095 1638 545 1110 −113 Enterobacter CONTIG485 GTC ORF with score 1166 to: cloacae (ai:7000790295) (or:Pseudomonas aeruginosa) 34266588_c2_1516 4525 21096 999 332 1221 −124 Bordetella S66937 (de:orf1 . . . orf3 {transposon-like sequence} pertussis (bordetella pertussis, genomic, 3 genes, 2300 nt).) 36588216_c2_1517 4526 21097 849 282 759 −75 Bordetella P39068 (ec:2.7.4.3) (de:adenylate kinase, (atp-amp pertussis transphosphorylase)) 13148911_c2_1518 4527 21098 840 279 100 −3 Klebsiella Contig544A GTC ORF with score 154 to: (ai:7000807998) pneumoniae (or:Pseudomonas aeruginosa) 32457308_c2_1520 4528 21099 516 171 116 −5 Aspergillus v1x1fj93.x GTC ORF with score 429 to: (ai: 177837) fumigatus (or:Zea mays) (sr:, maize) 31386283_c2_1525 4529 21100 831 276 487 −47 Enterobacter CONTIG468 GTC ORF with score 789 to: (ai:7501752829) cloacae (or:Klebsiella pneumoniae) 36458333_c2_1526 4530 21101 780 259 164 −9 Bos P04258 (sr:,bovine) (de:collagen alpha 1(iii) chain) primigenius taurus 32237688_c2_1531 4531 21102 1197 398 150 −8 Rattus M64793 (sr:rat (sprague-dawley) liver dna) (de:rat norvegicus salivary proline-rich protein (rp15) gene, complete cds.) 12994406_c2_1535 4532 21103 321 106 111 −7 Klebsiella Contig438A GTC ORF with score 111 to: (ai:7000772057) pneumoniae (or:Pseudomonas aeruginosa) 11223880_c2_1539 4533 21104 2874 957 384 −35 Klebsiella Contig435A GTC ORF with score 489 to: (ai:7000841821) pneumoniae (or:Enterobacter cloacae) 6509530_c2_1540 4534 21105 1719 572 365 −33 Lyme disease H70193 (sr:, lyme disease spirochete) spirochete 36426966_c2_1542 4535 21106 2094 697 162 −8 Nephila AF027735 (de:nephila clavipes minor ampullate silk clavipes protein misp 1 mrna, partial cds.) 36534833_c2_1547 4536 21107 516 171 129 −7 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32675916_c2_1549 4537 21108 1245 414 7081652_c2_1556 4538 21109 462 153 108 −4 Pinctada fucata D86074 (sr:pinctada fucata cdna to mrna) (de:pinctada fucata mrna for insoluble protein, complete cds.) 26645887_c2_1557 4539 21110 1863 620 1087 −110 Escherichia P32703 (de:hypothetical 60.5 kd protein in soxr-acs coli intergenic region (o549)) 31766253_c2_1567 4540 21111 933 310 1402 −143 Pseudomonas AB010087 (sr:pseudomonas aeruginosa (str:pao 1) dna) aeruginosa (de:pseudomonas aeruginosa rpsb, tsf, pyrh, frr genes for ribosomalprotein s2, elongation factor ts, ump kinase, ribosome recyclingfactor.complete cds.) 1430311_c2_1568 4541 21112 936 311 1117 −113 Pseudomonas AB010087 (sr:pseudomonas aeruginosa (str:pao 1) dna) aeruginosa (de:pseudomonas aeruginosa rpsb, tsf, pyrh, frr genes for ribosomalprotein s2, elongation factor ts, ump kinase, ribosome recyclingfactor.complete cds.) 31304057_c2_1572 4542 21113 1854 617 1121 −113 Escherichia P45568 (de:hypothetical 43.4 kd protein in frr-cdsa coli intergenic region) 13960431_c2_1574 4543 21114 729 242 146 −7 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 11772626_c2_1579 4544 21115 1275 424 869 −87 Escherichia P21645 (ec:2.3.1.—) (de:(ec 2.3.1.—) (fira protein) coli (rifampicin resistance protein)) 30485762_c2_1581 4545 21116 801 266 728 −72 Escherichia P10440 (ec:2.3.1.129) (de:(ec 2.3.1.129) (udp-n- coli acetylglucosamine acyltransferase)) 25525283_c2_1582 4546 21117 1140 379 983 −99 Escherichia F64742 (cl:lipid a disaccharide synthase) coli (ec:2.4.1.182) (mp:4 min) 16688503_c2_1596 4547 21118 813 270 129 −5 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 31931431_c2_1597 4548 21119 480 159 93 −2 mice|C57BL/ Q61414 (sr:,mouse) (de:keratin, type i cytoskeletal 15 6xCBA/ (cytokeratin 15) (k15) (ck 15)) CaJ hybrid 1459501_c2_1598 4549 21120 1644 547 2052 −212 Haemophilus P44341 (ec:6.3.4.2) (de:ctp synthase, (utp−−ammonia influenzae ligase) (ctp synthetase)) 24111717_c2_1601 4550 21121 330 109 167 −12 Haemophilus P44035 (de:hypothetical protein hi0673) influenzae 34511543_c2_1605 4551 21122 843 280 404 −38 Klebsiella Contig560A GTC ORF with score 404 to: (ai:7000772127) pneumoniae (or:Pseudomonas aeruginosa) 57287_c2_1607 4552 21123 2094 697 932 −93 Escherichia P33018 (de:hypothetical 31.3 kd protein in fole-cira coli intergenic region) 2473262_c2_1608 4553 21124 1572 523 511 −49 Escherichia Q57261 (de:hypothetical 39.1 kd protein in sure-cysc coli intergenic region) 11224078_c2_1614 4554 21125 1080 359 1695 −174 Pseudomonas P45684 (de:rna polymerase sigma factor rpos) aeruginosa 34581586_c2_1616 4555 21126 2685 894 667 −66 Klebsiella Contig485A GTC ORF with score 1068 to: pneumoniae (ai:7000842700) (or:Enterobacter cloacae) 34510308_c2_1619 4556 21127 1197 398 1730 −178 Pseudomonas P08280 (de:reca protein) aeruginosa 7151916_c2_1624 4557 21128 1272 423 16835205_c2_1627 4558 21129 675 224 120 −4 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 16517842_c2_1633 4559 21130 432 143 101 −4 Klebsiella Contig458A GTC ORF with score 648 to: (ai:7000794073) pneumoniae (or:Pseudomonas aeruginosa) 14261276_c2_1637 4560 21131 273 90 150 −11 Enterobacter CONTIG507 GTC ORF with score 150 to: (ai:7000772159) cloacae (or:Pseudomonas aeruginosa) 30739581_c2_1639 4561 21132 1626 541 407 −38 Pseudomonas P29369 (dc:glycerol metabolism activator (agmr aeruginosa protein)) 26020915_c2_1641 4562 21133 864 287 232 −20 Acinetobacter CONTIG189 GTC ORF with score 232 to: (ai:7000772163) baumannii C (or:Pseudomonas aeruginosa) 14947541_c3_1643 4563 21134 972 323 11132836_c3_1650 4564 21135 933 310 223 −17 Pseudomonas AF001355 (de:pseudomonas syringae pv. syringae dna syringae pv. binding protein hpkr (hpkr),histidine protein syringae kinase hpky (hpky), phosphate acceptor regulatoryprotein chey-2 (chey-2), ankyrin ankf(ankf), and catalase isozymecatalytic subunit catf (catf) . . . 12602038_c3_1659 4565 21136 441 146 94 −3 Saccharomyces P40552 (sr:,baker's yeast) (de:hypothetical 26.3 kd cerevisiae protein in pdr11-faa3 intergenic region) 32425826_c3_1663 4566 21137 444 147 98 −5 Enterobacter CONTIG507 GTC ORF with score 98 to: (ai:7000772185) cloacae (or:Pseudomonas aeruginosa) 16660330_c3_1668 4567 21138 435 144 106 −6 Toxocara canis U39815 (de:toxocara canis surface coat glycoprotein tes-120 precursor (nmuc-1)mrna, complete cds.) (nt:mucin-like apoprotein) 14163381_c3_1672 4568 21139 258 85 134 −9 Klebsiella Contig532A GTC ORF with score 134 to: (ai:7000772194) pneumoniae (or:Pseudomonas aeruginosa) 4041412_c3_1676 4569 21140 726 241 97 −2 Trypanosoma U22048 (fn:putative rna binding protein) (Trypanozoon) (de:trypanosoma brucei putative rna binding brucei brucei protein tbrrm1 gene,complete cds.) 24025382_c3_1677 4570 21141 345 114 35583518_c3_1678 4571 21142 276 91 14729080_c3_1680 4572 21143 585 194 94 −2 Rattus P47709 (sr:,rat) (de:rabphilin-3a) norvegicus 22783287_c3_1682 4573 21144 621 206 125 −7 mice|C57BL/ Q06666 (sr:,mouse) (de:octapeptide-repeat protein t2) 6xCBA/ CaJ hybrid 1422055_c3_1683 4574 21145 615 204 500933_c3_1686 4575 21146 552 183 103 −5 mice|C57BL/ AJ005566 (fn:cornified cell envelope precursor) (sr:house 6xCBA/ mouse) (de:mus musculus sprr2h gene.) CaJ hybrid 29963530_c3_1689 4576 21147 918 305 158 −11 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 16925691_c3_1693 4577 21148 333 110 92 −3 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 30251256_c3_1695 4578 21149 228 75 12972637_c3_1701 4579 21150 1038 345 997 −100 Escherichia P32695 (de:hypothetical 36.8 kd protein in dinf-qor coli intergenic region) 32292716_c3_1703 4580 21151 561 186 146 −10 Enterobacter CONTIG511 GTC ORF with score 146 to: (ai:7000772225) cloacae (or:Pseudomonas aeruginosa) 411566_c3_1706 4581 21152 1113 370 93 −2 Klebsiella Contig348A GTC ORF with score 357 to: (ai:7000770786) pneumoniae (or:Pseudomonas aeruginosa) 26665631_c3_1707 4582 21153 417 138 25939712_c3_1709 4583 21154 417 138 158 −11 Mycobacterium Z97050 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 10/162.) (nt:rv0163, (mtci28.03), len: 151. unknown, but) 12370901_c3_1710 4584 21155 459 152 149 −9 Alphaherpes- P11675 (sr:indiana-funkhauser/becker,prv) virus (de:immediate-early protein ie180) pseudorabies virus PRV 22109657_c3_1711 4585 21156 411 136 116 −6 Chlamy- S50755 domonas reinhardtii strain UTEX 1061 24417337_c3_1713 4586 21157 561 186 106 −3 Homo sapiens P23677 (sr:,human) (ec:2.7.1.127) (de:1,4,5- trisphosphate 3-kinase) (ip3k) (ip3 3-kinase)) 26306466_c3_1719 4587 21158 1836 611 617 −60 Pseudomonas Q02541 (sr:,pvtomato) (ec:2.7.3.—) (de:sensor protein syringae cops,) 12630417_c3_1720 4588 21159 999 332 352 −32 Enterobacter CONTIG503 GTC ORF with score 352 to: (ai:7000772242) cloacae (or:Pseudomonas aeruginosa) 14579686_c3_1721 4589 21160 666 221 215 −18 Enterobacter CONTIG461 GTC ORF with score 215 to: (ai:7000772243) cloacae (or:Pseudomonas aeruginosa) 10010465_c3_1723 4590 21161 402 133 96 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 20941342_c3_1725 4591 21162 411 136 33863530_c3_1727 4592 21163 591 196 31878211_c3_1728 4593 21164 846 281 165 −12 Mycobacterium AL022121 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 155/162.) (nt:rv3676, (mtv025.024), len: 224. probable) 5318841_c3_1729 4594 21165 540 179 1000 −3 Saccharomyces P53832 (sr:,baker's yeast) (de:precursor) cerevisiae 13775808_c3_1735 4595 21166 441 146 92 −4 Klebsiella Contig549A GTC ORF with score 118 to: (ai:7000770025) pneumoniae (or:Pseudomonas aeruginosa) 4964650_c3_1738 4596 21167 336 111 201 −16 Caedibacter U04523 (de:caedibacter taeniospiralis 116 r body taeniospiralis synthesis and assembly (rebarebb, rebc, rebd) genes, complete cds.) 14120427_c3_1742 4597 21168 261 86 118 −7 Bacteriophage G42465 phi-R73 12126031_c3_1743 4598 21169 888 295 155 −8 Rhizobium sp. P55393 (sr:ngr234,) (de:putative replication protein a) 32472707_c3_1744 4599 21170 1764 587 126 −5 Medicago S53504 (sr:, alfalfa) sativa 16094576_c3_1749 4600 21171 852 283 353 −32 Enterobacter CONTIG485 GTC ORF with score 353 to: (ai:7000772271) cloacae (or:Pseudomonas aeruginosa) 10817557_c3_1750 4601 21172 654 217 36614780_c3_1751 4602 21173 600 199 104 −3 Schizo- D89103 (sr:schizosaccharomyces pombe (strain:pr745) saccharomyces cdna to mrna) (de:schizosaccharomyces pombe pombe mrna, partial cds, clone: sy 0143.) (nt:unnamed protein product) 25901032_c3_1752 4603 21174 507 168 122 −7 Aspergillus Contig7774 GTC ORF with score 215 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 9885041_c3_1761 4604 21175 540 179 120 −6 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene domesticus coding for phosvitin, exons 23 and 24.) 7163382_c3_1763 4605 21176 954 317 14241451_c3_1764 4606 21177 375 124 10651581_c3_1769 4607 21178 465 154 93 −3 Toxocara canis U39815 (de:toxocara canis surface coat glycoprotein tes-120 precursor (nmuc-1)mrna, complete cds.) (nt:mucin-like apoprotein) 32595641_c3_1770 4608 21179 1119 372 261 −23 Enterobacter CONTIG485 GTC ORF with score 277 to: (ai:7000790246) cloacae (or:Pseudomonas aeruginosa) 16833535_c3_1771 4609 21180 972 323 839 −84 Escherichia P52149 (de:gene 32 protein (orf273)) coli 26692040_c3_1772 4610 21181 783 260 14897905_c3_1776 4611 21182 1245 414 16847830_c3_1779 4612 21183 480 159 109 −4 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 24880292_c3_1790 4613 21184 594 197 167 −13 Klebsiella Contig550A GTC ORF with score 219 to: (ai:7000787503) pneumoniae (or:Pseudomonas aeruginosa) 22704652_c3_1792 4614 21185 480 159 94 −2 Aspergillus Contig7924 GTC ORF with score 445 to: (ai:279944) fumigatus (or:Caenorhabditis elegans) (de:caenorhabditis elegans cosmid t05a10, complete sequence.) (nt:similar to 11-s plant seed storage proteins, zinc) 33847875_c3_1796 4615 21186 636 211 184 −16 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 12605180_c3_1798 4616 21187 2223 740 2253 −234 Enterobacter CONTIG485 GTC ORF with score 2253 to: cloacae (ai:7000772320) (or:Pseudomonas aeruginosa) 10806630_c3_1802 4617 21188 750 249 136 −6 Volvox carteri S22697 24879555_c3_1813 4618 21189 402 133 175 −14 Enterobacter CONTIG485 GTC ORF with score 175 to: (ai:7000772335) cloacae (or:Pseudomonas aeruginosa) 469378_c3_1815 4619 21190 357 118 26579066_c3_1816 4620 21191 990 329 664 −65 Enterobacter CONTIG485 GTC ORF with score 664 to: (ai:7000772338) cloacae (or:Pseudomonas aeruginosa) 16260201_c3_1817 4621 21192 1677 558 926 −93 Enterobacter CONTIG485 GTC ORF with score 926 to: (ai:7000772339) cloacae (or:Pseudomonas aeruginosa) 25598331_c3_1818 4622 21193 3225 1074 2350 −244 Enterobacter CONTIG485 GTC ORF with score 2350 to: cloacae (ai:7000772340) (or:Pseudomonas aeruginosa) 13926902_c3_1819 4623 21194 792 263 253 −22 Klebsiella Contig336A GTC ORF with score 161 to: (ai:7000698859) pneumoniae (or:Archaeoglobus fulgidus) 35633343_c3_1829 4624 21195 417 138 22751633_c3_1838 4625 21196 789 262 507 −48 Escherichia P76256 (de:hypothetical 25.2 kd protein in fadd-pabb coli intergenic region) 15056642_c3_1839 4626 21197 786 261 116 −4 Nephila A44112 clavipes 16104758_c3_1840 4627 21198 510 169 127 −7 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 31893878_c3_1842 4628 21199 585 194 94 −3 Enterobacter CONTIG24 GTC ORF with score 133 to: (ai:286830) cloacae (or:Ensis minor) (sr:ensis minor (clone: 1/6) male adult gonads cdna to mrna) (de:ensis minor (clone 1/6) nuclear protein mrna, complete cds.) (nt:putative) 29556508_c3_1843 4629 21200 1203 400 507 −48 Haemophilus P44901 (de:hypothetical protein hi0849) influenzae 3241631_c3_1845 4630 21201 462 153 136 −8 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 20719215_c3_1849 4631 21202 1170 389 345 −31 Aquifex A70361 aeolicus 2392080_c3_1850 4632 21203 1788 595 104 −4 Drosophila X05285 (sr:fruit fly) (de:d. melanogaster gc-rich melanogaster dispersed repeat gcr6 (fibrillarin genefragment).) (nt:put.fibrillarin gene) 5113468_c3_1862 4633 21204 930 309 605 −59 Cyano- S76626 (cl:atp-binding cassette homology) (sr:pcc bacterium 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 24714067_c3_1864 4634 21205 1872 623 32681541_c3_1865 4635 21206 984 327 16267666_c3_1867 4636 21207 456 151 109 −6 Klebsiella Contig438A GTC ORF with score 377 to: (ai:7000823599) pneumoniae (or:Enterobacter cloacae) 31350432_c3_1868 4637 21208 462 153 94 −5 longfin squid S56117 (sr:, longfin squid) 11207331_c3_1869 4638 21209 348 115 128 −8 Orgyia O10341 (sr:,opmnpv) (de:hypothetical 29.3 kd protein pseudotsugata (orf92)) multi- nucleocapsid nuclear polyhedrosis virus OpMNPV 26439540_c3_1871 4639 21210 678 225 25806461_c3_1881 4640 21211 690 229 141 −8 Klebsiella Contig443A GTC ORF with score 820 to: (ai:7000832539) pneumoniae (or:Enterobacter cloacae) 4581451_c3_1882 4641 21212 2178 725 391 −36 Enterobacter CONTIG465 GTC ORF with score 820 to: (ai:7501748356) cloacae (or:Klebsiella pneumoniae) 10551656_c3_1883 4642 21213 195 64 103 −6 Pseudomonas U15394 (de:pseudomonas aeruginosa clone em76 aeruginosa ribosomal protein s2-like gene, complete cds.) (nt:similar to s. platensis ribosomal protein s2,) 36353811_c3_1889 4643 21214 1503 500 1359 −139 Pseudomonas Q59640 (ec:2.7.7.41) (de:synthase)) aeruginosa 15900338_c3_1892 4644 21215 1356 451 1010 −102 Escherichia P37764 (de:hypothetical 49.1 kd protein in cdsa-hlpa coli intergenic region) 26352066_c3_1895 4645 21216 999 332 147 −6 Homo sapiens Q07283 (sr:,human) (de:trichohyalin) 14508285_c3_1897 4646 21217 546 181 185 −14 Yersinia Y12468 (de:y. enterocolitica omph gene.) enterocolitica 15625016_c3_1899 4647 21218 483 160 403 −37 Escherichia P21774 (ec:4.2.1.—) (de:(3r)-hydroxymyristoyl-(acyl coli carrier protein) dehydratase,) 10954456_c3_1902 4648 21219 1671 556 31817501_c3_1903 4649 21220 1224 407 124 −4 Homo sapiens B35363 (sr:,man) 16662668_c3_1905 4650 21221 2061 686 123 −4 mice|C57BL/ A28996 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ Cat hybrid 32222918_c3_1906 4651 21222 999 332 1131 −115 Escherichia A43452 (cl:acetyl-coa carboxylase,carboxyltransferase coli alpha chain) (ec:6.4.1.2) (mp:4.3 min) 32675283_c3_1907 4652 21223 1398 465 707 −70 Escherichia P52097 (de:cell cycle protein mesj) coli 36422137_c3_1910 4653 21224 501 166 90 −3 Klebsiella Contig549A GTC ORF with score 124 to: (ai:7000783409) pneumoniae (or:Pseudomonas aeruginosa) 25649167_c3_1912 4654 21225 558 185 134 −7 Haloferax sp. P21561 (sr:aa 2.2,) (de:hypothetical 50.6 kd protein in the 5′region of gyra and gyrb (orf 3) 12635942_c3_1914 4655 21226 813 270 510 −49 Haemophilus O05029 (de:hypothetical protein hi0672) influenzae 25409425_c3_1918 4656 21227 1200 399 1532 −157 Escherichia S57525 (cl:alcohol dehydrogenase:long-chain alcohol coli dehydrogenase homology) (ec:1.1.1.1) 36038900_c3_1920 4657 21228 495 164 556 −54 Escherichia P36663 (de:hypothetical 16.9 kd protein in sure-cysc coli intergenic region (orf0)) 35786706_c3_1921 4658 21229 588 195 105 −3 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 797641_c3_1923 4659 21230 1122 373 530 −51 Pseudomonas P45683 (ec:2.1.1.77) (de:(fragment)) aeruginosa 24742207_c3_1924 4660 21231 909 302 1527 −156 Pseudomonas P45682 (de:lipoprotein nlpd/lppb homolog precursor) aeruginosa 22927208_c3_1932 4661 21232 492 163 103 −3 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 6328280_c3_1935 4662 21233 435 144 99 −3 Riftia S28774 (cl:unassigned collagens) pachyptila 4938168_c3_1947 4663 21234 975 324 102 −2 migratory AJ000390 (sr:migratory locust) (de:locusta migratoria locust mrna for nachr alpha1 subunit.) 1346955_c3_1951 4664 21235 1080 359 142 −6 Homo sapiens AF007575 (sr:human) (de:homo sapiens es/130-related protein mrna, partial cds.) 12944552_c3_1952 4665 21236 684 227 100 −2 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 7159387_c3_1955 4666 21237 966 321 96 −1 Canis A45195 (cl:guanylate cyclase catalytic domain familiaris homology) (sr:, dog) 31652037_f1_1 4667 21238 210 69 223 −18 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to pseudomonas fluorescens phzf gene) 36042033_f1_6 4668 21239 663 220 95 −3 Enterobacter CONTIG415 GTC ORF with score 204 to: (ai:7000776594) cloacae (or:Pseudomonas aeruginosa) 30667591_f2_7 4669 21240 726 241 1091 −110 Pseudomonas AF005404 (de:pseudomonas aeruginosa pyocyanine aeruginosa biosynthesis operon, completesequence.) (nt:similar to bacterial pyridoxamine-5′- phosphate) 36616400_c1_18 4670 21241 993 330 581 −56 Rhizobium sp. P55615 (sr:ngr234,) (de:putative transposase y4pf/y4sb) 7292041_f2_2 4671 21242 324 107 291 −26 Pseudomonas AF074954 (de:pseudomonas aeruginosa plasmid ppa-1 aeruginosa is26 transposase (tnpa) gene,partial cds; beta- lactamase (shv-2a) gene, complete cds; and tn1721 methyl-accepting chemotaxis-like protein gene, partial cds.) (nt:orf-1) 12616306_f2_3 4672 21243 198 65 9767327_f3_4 4673 21244 768 256 491 −47 Rhodo- L77975 (sr:rhodopseudomonas viridis (library: pseudomonas dsm134) mrna) (de:rhodopseudomonas viridis viridis homospermidine synthase mrna, completecds.) (nt:putative) 15647500_c1_6 4674 21245 576 192 133 −9 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 16613583_f1_2 4675 21246 2865 954 108 −5 Klebsiella Contig503A GTC ORF with score 129 to: (ai:7000772531) pneumoniae (or:Pseudomonas aeruginosa) 12973316_f1_5 4676 21247 414 137 127 −7 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 HHV-6 major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 30744566_f1_6 4677 21248 447 148 92 −2 Homo sapiens PN0099 (sr:, man) 16688900_f1_7 4678 21249 1842 613 129 −8 Klebsiella Contig503A GTC ORF with score 129 to: (ai:7000772531) pneumoniae (or:Pseudomonas aeruginosa) 11757943_f1_8 4679 21250 720 239 192 −14 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 16505016_f1_9 4680 21251 405 134 118 −7 Aspergillus Contig8154 GTC ORF with score 433 to: (ai:177837) fumigatus (or:Zea mays) (sr:, maize) 12902018_f1_10 4681 21252 198 65 16114687_f1_13 4682 21253 1752 583 2808 −292 Pseudomonas X82644 (de:p. aeruginosa pchd, pchc, pchb and pcha aeruginosa genes.) (nt:similarity to adenylate-forming, activating) 31883291_f1_14 4683 21254 642 213 158 −10 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29802205_f1_15 4684 21255 1791 596 2494 −259 Pseudomonas Q51508 (ec:5.4.99.6) (de:salicylate biosynthesis aeruginosa isochorismate synthase,) 10678768_f1_18 4685 21256 1332 443 93 −2 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus glutamine 6xCBA/ repeat protein-1 mrna, complete cds.) CaJ hybrid (nt:grp-1) 23619153_f1_19 4686 21257 3060 1019 3828 −9999 Escherichia P07671 (de:excinuclease abc subunit a) coli 2442812_f1_21 4687 21258 1404 467 193 −13 Aspergillus Contig9635 GTC ORF with score 392 to: (ai:7000783985) fumigatus (or:Pseudomonas aeruginosa) 10805175_f1_24 4688 21259 1071 356 319 −29 Enterobacter CONTIG372 GTC ORF with score 319 to: (ai:7000772548) cloacae (or:Pseudomonas aeruginosa) 26016412_f1_25 4689 21260 348 115 104 −6 Staphylococcus CONTIG063 GTC ORF with score 194 to: (ai:7000730137) epidermidis C (or:Streptococcus pneumoniae) 30181336_f1_32 4690 21261 1014 337 354 −33 Enterobacter CONTIG251 GTC ORF with score 1114 to: cloacae (ai:7501731341) (or:Klebsiella pneumoniae) 29689782_f1_35 4691 21262 594 197 243 −21 Enterococcus CONTIG367 GTC ORF with score 118 to: (ai:7500982486) faecium B (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1485001-1738505 nt, position(7/7).) 29797055_f1_36 4692 21263 438 145 121 −8 Clostridium Contig170H GTC ORF with score 121 to: (ai:7000772560) acetobutylicum (or:Pseudomonas aeruginosa) 26303941_f1_37 4693 21264 273 90 183 −14 Indian corn S58640 (sr:, maize) (mp:ir(b)) 11770802_f1_39 4694 21265 681 226 340 −31 Klebsiella Contig236A GTC ORF with score 340 to: (ai:7000772563) pneumoniae (or:Pseudomonas aeruginosa) 22792337_f1_40 4695 21266 297 98 178 −14 Enterococcus CONTIG391 GTC ORF with score 178 to: (ai:7000772564) faecium B (or:Pseudomonas aeruginosa) 9848581_f1_42 4696 21267 348 115 337 −31 Klebsiella Contig049A GTC ORF with score 95 to: (ai:112597) pneumoniae (or:Eikenella corrodens) (de:e. corrodens hag2, tufa, fus, rpsg and rpsl genes encodinghemagglutinin protein, elongation factor tu, elongation factor g,ribosomal protein s7, and ribosomal protein s12.) 13725040_f1_46 4697 21268 4242 1413 1659 −171 Klebsiella Contig494A GTC ORF with score 1659 to: pneumoniae (ai :7000831624) (or:Enterobacter cloacae) 29978791_f1_55 4698 21269 444 147 117 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 259718_f1_59 4699 21270 900 299 319 −29 Enterobacter CONTIG253 GTC ORF with score 319 to: (ai:7000772583) cloacae (or:Pseudomonas aeruginosa) 9866441_f1_61 4700 21271 363 120 111 −6 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) dna, horikoshii cl:pyrococcus horikoshi) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) 32552266_f2_76 4701 21272 594 197 157 −12 Klebsiella Contig503A GTC ORF with score 157 to: (ai:7000772600) pneumoniae (or:Pseudomonas aeruginosa) 11744563_f2_79 4702 21273 507 168 153 −9 Gallus gallus A90458 (cl:collagen alpha 1(i) chain:fibrillar collagen domesticus carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 29973943_f2_80 4703 21274 702 233 192 −15 Pseudomonas P15276 (de:algr3)) aeruginosa 11183167_f2_85 4704 21275 1557 518 14714201_f2_94 4705 21276 960 319 528 −51 Pseudomonas Q51507 (de:salicylate biosynthesis protein pchb) aeruginosa 15082333_f2_98 4706 21277 534 177 138 −10 Enterobacter CONTIG501 GTC ORF with score 318 to: (ai:7501738048) cloacae (or:Klebsiella pneumoniae) 30645157_f2_100 4707 21278 591 196 427 −40 Klebsiella Contig546A GTC ORF with score 725 to: (ai:7000826725) pneumoniae (or:Enterobacter cloacae) 34480031_f2_104 4708 21279 444 147 115 −6 Sus scrofa I47141 (sr:, domestic pig) domestica 16096041_f2_115 4709 21280 1425 474 193 −14 Escherichia A04439 (mp:72 min) coli 34586541_f2_116 4710 21281 648 215 191 −15 Klebsiella Contig268A GTC ORF with score 625 to: (ai:7000815304) pneumoniae (or:Enterobacter cloacae) 26801952_f2_118 4711 21282 666 221 97 −3 Klebsiella Contig113A GTC ORF with score 726 to: (ai:7000815302) pneumoniae (or:Enterobacter cloacae) 26069582_f2_120 4712 21283 222 73 115 −7 Klebsiella Contig207A GTC ORF with score 228 to: (ai:7000815307) pneumoniae (or:Enterobacter cloacae) 10425041_f2_121 4713 21284 642 213 333 −30 Enterobacter CONTIG121 GTC ORF with score 333 to: (ai:7000772645) cloacae (or:Pseudomonas aeruginosa) 22035631_f2_123 4714 21285 639 212 370 −34 Enterobacter CONTIG246 GTC ORF with score 370 to: (ai:7000772647) cloacae (or:Pseudomonas aeruginosa) 14072708_f2_129 4715 21286 768 255 357 −33 Klebsiella Contig236A GTC ORF with score 1120 to: pneumoniae (ai:7000826623) (or:Enterobacter cloacae) 14240681_f2_149 4716 21287 555 184 243 −20 Enterobacter CONTIG120 GTC ORF with score 386 to (ai:7000772747) cloacae (or:Pseudomonas aeruginosa) 22478936_f2_157 4717 21288 312 103 281 −25 Enterococcus CONTIG534 GTC ORF with score 422 to: (ai:7000736726) faecalis (or:Enterococcus faecium) 13144780_f3_162 4718 21289 471 156 129 −7 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 34475762_f3_166 4719 21290 603 200 159 −11 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 6301086_f3_168 4720 21291 504 167 115 −4 equine AF030027 (fn:very large tegument protein) (de:equine herpesvirus herpesvirus 4 strain ns80567, complete type 4 EHV-4 genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 35652308_f3_171 4721 21292 765 254 133 −9 Klebsiella Contig503A GTC ORF with score 157 to: (ai:7000772600) pneumoniae (or:Pseudomonas aeruginosa) 11725652_f3_175 4722 21293 411 136 127 −7 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 12283582_f3_177 4723 21294 1554 517 1256 −128 Pseudomonas X82644 (de:p. aeruginosa pchd, pchc, pchb and pcha aeruginosa genes.) (nt:similarity to thioesterases) 24706437_f3_178 4724 21295 1653 550 9969513_f3_183 4725 21296 573 190 334 −29 Micrococcus JQ0405 luteus 16617308_f3_184 4726 21297 1440 479 604 −58 Micrococcus JQ0405 luteus 32281651_f3_185 4727 21298 834 277 447 −41 Micrococcus JQ0405 luteus 9801066_f3_192 4728 21299 420 139 262 −23 Klebsiella Contig268A GTC ORF with score 696 to: (ai:7000820763) pneumoniae (or:Enterobacter cloacae) 23828752_f3_200 4729 21300 762 253 291 −26 Klebsiella Contig207A GTC ORF with score 410 to: (ai:7000813597) pneumoniae (or:Enterobacter cloacae) 16267882_f3_201 4730 21301 612 203 370 −34 Enterobacter CONTIG246 GTC ORF with score 816 to: (ai:7501727816) cloacae (or:Klebsiella pneumoniae) 12931277_f3_202 4731 21302 270 89 152 −11 Acinetobacter CONTIG087 GTC ORF with score 152 to: (ai:7000772726) baumannii C (or:Pseudomonas aeruginosa) 24260067_f3_204 4732 21303 1227 408 702 −69 Klebsiella Contig236A GTC ORF with score 1718 to: pneumoniae (ai:7000815185) (or:Enterobacter cloacae) 21698340_f3_209 4733 21304 1230 409 773 −77 Enterobacter CONTIG253 GTC ORF with score 1078 to: cloacae (ai:7501726633) (or:Klebsiella pneumoniae) 10751092_f3_210 4734 21305 1677 558 832 −83 Eikenella P35649 (de:hypothetical 66.3 kd protein in hag2 corrodens 5′region 16266063_f3_211 4735 21306 957 318 406 −38 Eikenella P35648 (de:hemagglutinin 2) 4417906_f3_212 4736 21307 447 148 357 −33 Klebsiella Contig048A GTC ORF with score 357 to: (ai:7000772736) pneumoniae (or:Pseudomonas aeruginosa) 1223266_13_219 4737 21308 4074 1357 2974 −9999 Klebsiella Contig494A GTC ORF with score 2974 to: pneumoniae (ai:7000772743) (or:Pseudomonas aeruginosa) 31538957_f3_221 4738 21309 438 145 161 −12 Enterobacter CONTIG460 GTC ORF with score 161 to: (ai:7000772745) cloacae (or:Pseudomonas aeruginosa) 283133_f3_223 4739 21310 1047 348 386 −36 Enterobacter CONTIG120 GTC ORF with score 386 to: (ai:7000772747) cloacae (or:Pseudomonas aeruginosa) 2625883_f3_225 4740 21311 1356 451 767 −76 Enterobacter CONTIG253 GTC ORF with score 1078 to: cloacae (ai:7501726633) (or:Klebsiella pneumoniae) 15730413_f3_227 4741 21312 525 174 102 −3 Aspergillus Contig8154 GTC ORF with score 433 to: (ai:177837) fumigatus (or:Zea mays) (sr:, maize) 2815777_f3_228 4742 21313 516 171 10836578_c1_240 4743 21314 717 238 15822211_c1_244 4744 21315 372 123 284 −25 Escherichia P16920 (de:preprotein translocase sece subunit) coli 6380093_c1_245 4745 21316 543 180 688 −68 Escherichia P16921 (de:transcription antitermination protein nusg) coli 10438892_c1_249 4746 21317 615 204 120 −5 Homo sapiens X06814 (sr:human) (de:human mrna for hul-70k small nuclear rnp protein (rnp12).) (nt:hul-70k protein (234 aa)) 12602011_c1_253 4747 21318 291 96 262 −23 Enterobacter CONTIG460 GTC ORF with score 415 to: (ai:7501761920) cloacae (or:Klebsiella pneumoniae) 16992943_c1_263 4748 21319 4212 1403 6330 −9999 Pseudomonas P19176 (ec:2.7.7.6) (de:beta′ chain) (rna polymerase putida beta′ subunit) 31692580_c1_274 4749 21320 648 215 735 −73 Haemophilus P55836 (sr:,haemophilus actinomycetemcomitans) actinomycetem- (de:50s ribosomal protein 14) comitans 25676708_c1_276 4750 21321 207 68 237 −20 Escherichia P02429 (de:50s ribosomal protein 129) coli 3225806_c1_279 4751 21322 390 129 353 −32 Escherichia F65123 (cl:escherichia coli ribosomal protein s14) coli (mp:73 min) 14713955_c1_280 4752 21323 582 193 460 −43 Escherichia A02714 (de:ribosomal protein s8 - escherichia coli this coli protein binds to 16s ribosomal rna.) 6525311_c1_281 4753 21324 354 117 339 −31 Haemophilus P44356 (de:50s ribosomal protein 118) influenzae 24353378_c1_282 4754 21325 504 167 619 −60 Escherichia B65123 (cl:escherichia coli ribosomal protein s5) coli (mp:73 min) 15912812_c1_286 4755 21326 1017 338 1617 −166 Pseudomonas AF047025 (de:pseudomonas aeruginosa ribosomal protein aeruginosa s4 (rpsd) gene, partialcds; dna-directed rna polymerase alpha chain (rpoa), ribosomallarge subunit protein 117 (rplq), and catalase isozyme a (kata)genes, complete cds; and bacterioferriti . . . 24820452_c1_288 4756 21327 1449 482 2605 −271 Pseudomonas AF047025 (de:pseudomonas aeruginosa ribosomal protein aeruginosa s4 (rpsd) gene, partialcds; dna-directed rna polymerase alpha chain (rpoa), ribosomallarge subunit protein 117 (rplq), and catalase isozyme a (kata)genes, complete cds; and bacterioferriti . . . 266377_c1_289 4757 211328 3456 1151 1102 −111 Micrococcus JQ0406 luteus 24354166_c1_290 4758 21329 1551 516 1189 −121 Escherichia P77726 (de:hypothetical 49.0 kd protein in abpa-cyoe coli intergenic region) 12305406_c1_291 4759 21330 591 196 113 −4 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 HHV-6 major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 22753167_c1_292 4760 21331 861 286 102 −4 Klebsiella Contig554A GTC ORF with score 455 to: (ai:7000842053) pneumoniae (or:Enterobacter cloacae) 31500751_c1_295 4761 21332 420 139 100 −4 Caenorhabditis Z81518 (de:caenorhabditis elegans cosmid f28d9, elegans complete sequence.) (nt:cdna est emb1:c09269 comes from this gene; cdna est) 31346042_c1_296 4762 21333 891 296 392 −37 Enterobacter CONTIG502 GTC ORF with score 681 to: (ai:7501793383) cloacae (or:Klebsiella pneumoniae) 16927277_c1_297 4763 21334 2094 697 187 −12 Klebsiella Contig554A GTC ORF with score 189 to: (ai:7000842050) pneumoniae (or:Enterobacter cloacae) 33672942_c1_300 4764 21335 2844 947 3467 −9999 Pseudomonas AF074705 (de:pseudomonas aeruginosa aeruginosa dihydroaeruginoic acid synthetase (pche) andpyochelin synthetase (pchf) genes, complete cds.) (nt:peptide synthetase) 32671958_c1_301 4765 21336 4563 1520 7595 −9999 Pseudomonas AF074705 (de:pseudomonas aeruginosa aeruginosa dihydroaeruginoic acid synthetase (pche) andpyochelin synthetase (pchf) genes, complete cds.) (nt:peptide synthetase) 15682875_c2_304 4766 21337 762 253 127 −6 Mycobacterium Z95557 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 153/162.) (nt:rv3600c, (mtcy07h7b.22), len: 272. unknown,) 3220391_c2_306 4767 21338 1230 409 1741 −179 Escherichia A91478 (cl:translation elongation factor tu:translation coli elongation factor tu homology) (mp:90 min) 29946005_c2_309 4768 21339 765 254 835 −83 Escherichia S12573 (cl:escherichia coli ribosomal protein 11) coli (mp:90 min) 2616532_c2_310 4769 21340 606 201 558 −54 Salmonella S10895 (cl:escherichia coli ribosomal protein 110) choleraesuis serotype typhimurium 31923535_c2_311 4770 21341 411 136 426 −40 Pseudomonas P31855 (de:50s ribosomal protein 17/112) putida 36567806_c2_312 4771 21342 4092 1363 6325 −9999 Pseudomonas P19175 (ec:2.7.7.6) (de:beta chain) (rna polymerase putida beta subunit)) 4022952_c2_317 4772 21343 372 123 581 −56 Escherichia S13738 (cl:escherichia coli ribosomal protein s12) coli (mp:73 min) 25400817_c2_318 4773 21344 492 163 563 −54 Haemophilus G64078 (cl:escherichia coli ribosomal protein s7) influenzae 12348955_c2_319 4774 21345 2151 716 2542 −264 Escherichia G65127 (cl:translation elongation factor g:translation coli elongation factor tu homology) (mp:73 min) 99025_c2_320 4775 21346 1224 407 1739 −179 Salmonella S13560 (cl:translation elongation factor tu:translation choleraesuis elongation factor tu homology) serotype typhimurium 22695143_c2_321 4776 21347 318 105 490 −47 Haemophilus P44378 (de:30s ribosomal protein s10) influenzae 30760928_c2_324 4777 21348 837 278 1200 −122 Yersinia P49239 (de:50s ribosomal protein 12) enterocolitica 13949053_c2_329 4778 21349 429 142 544 −52 Haemophilus P55837 (sr:,haemophilus actinomycetemcomitans) actinomycetem- (de:50s ribosomal protein 116) comitans 35442707_c2_330 4779 21350 411 136 533 −51 Escherichia P02411 (de:50s ribosomal protein 114) coli 6381693_c2_331 4780 21351 327 108 348 −32 Escherichia P02425 (de:50s ribosomal protein 124) coli 4160452_c2_336 4781 21352 357 118 464 −44 Escherichia A23807 (cl:escherichia coli ribosomal protein s13) coli (mp:73 min) 24877080_c2_337 4782 21353 408 135 551 −53 Haemophilus I64094 (cl:escherichia coli ribosomal protein s11) influenzae 22134657_c2_340 4783 21354 393 130 654 −64 Pseudomonas AF047025 (de:pseudomonas aeruginosa ribosomal protein aeruginosa s4 (rpsd) gene, partialcds; dna-directed rna polymerase alpha chain (rpoa) ribosomallarge subunit protein 117 (rplq), and catalase isozyme a (kata)genes, complete cds; and bacterioferriti 25511292_c2_343 4784 21355 606 201 652 −64 Pseudomonas P77930 (de:bacterioferritin (bfr)) putida 1457278_c2_345 4785 21356 444 147 386 −36 Klebsiella Contig354A GTC ORF with score 426 to: (ai:7000841721) pneumoniae (or:Enterobacter cloacae) 31900082_c2_348 4786 21357 396 131 236 −20 Acinetobacter CONTIG228 GTC ORF with score 236 to: (ai:7000772872) baumannii C (or:Pseudomonas aeruginosa) 4348463_c2_353 4787 21358 744 247 309 −27 Pseudomonas P40947 (de:single-strand binding protein (ssb) (helix- aeruginosa destabilizing protein)) 16297901_c2_357 4788 21359 795 264 192 −15 Enterobacter CONTIG502 GTC ORF with score 192 to: (ai:7000772881) cloacae (or:Pseudomonas aeruginosa) 2441062_c2_361 4789 21360 963 320 1537 −158 Pseudomonas P40883 (de:regulatory protein pchr) aeruginosa 35828952_c2_363 4790 21361 1320 439 160 −8 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 17039581_c2_366 4791 21362 1107 368 1613 −166 Pseudomonas AF074705 (de:pseudomonas aeruginosa aeruginosa dihydroaeruginoic acid synthetase (pchc) andpyochelin synthetase (pchf) genes, complete cds.) (nt:peptide synthetase) 10275633_c2_372 4792 21363 630 209 106 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 16925067_c2_373 4793 21364 612 203 120 −5 Homo sapiens X87248 (sr:human) (de:h. sapiens mrna for hp8 protein.) 11074140_c3_375 4794 21365 951 316 536 −51 Escherichia P06709 (ec:6.3.4.15) (de:coa-carboxylase) synthetase), coli (biotin--protein ligase)) 23572186_c3_382 4795 21366 435 144 542 −52 Escherichia V00339 (de:e. coli operon rpobc coding for the beta- coli and beta′-subunits of rnapolymerase (genes rpoc and rpob), and genes rpll, rlpj, rpla, andrplk coding for 50s ribosomal subunit proteins 17/112, 110, 11, and 111, respectively. (map position 8 . . . 35828843_c3_392 4796 21367 432 143 94 −2 Homo sapiens AF026402 (sr:human) (de:homo sapiens u5 snrnp 100 kd protein mrna, complete cds.) (nt:dead-box, rs domain; prp28p homolog; putative rna) 30723261_c3_395 4797 21368 798 265 224 −19 Klebsiella Contig494A GTC ORF with score 224 to: (ai:7000772919) pneumoniae (or:Pseudomonas aeruginosa) 2994203_c3_397 4798 21369 513 170 143 −10 Acinetobacter CONTIG065 GTC ORF with score 143 to: (ai:7000772921) baumannii C (or:Pseudomonas aeruginosa) 16603591_c3_402 4799 21370 672 223 801 −80 Escherichia P02386 (de:50s ribosomal protein 13) coli 1444515_c3_405 4800 21371 390 129 289 −25 Haemophilus P55839 (sr:,haemophilus actinomycetemcomitans) actinomycetem- (de:50s ribosomal protein 123) comitans 14173592_c3_407 4801 21372 288 95 411 −38 Haemophilus I64092 (cl:escherichia coli ribosomal protein s19) influenzae 24881718_c3_408 4802 21373 345 114 389 −36 Haemophilus P44360 (de:50s ribosomal protein 122) influenzae 22517841_c3_409 4803 21374 699 232 847 −84 Escherichia H23129 (cl:escherichia coli ribosomal protein s3) coli (mp:73 min) 16831578_c3_410 4804 21375 273 90 310 −28 Escherichia P02373 (de:30s ribosomal protein s17) coli 16832152_c3_411 4805 21376 546 181 668 −65 Acyrthosiphon P46178 (de:50s ribosomal protein 15) kondoi endosymbiont 25907183_c3_413 4806 21377 669 222 601 −58 Haemophilus B64094 (cl:escherichia coli ribosomal protein 16) influenzae 31926017_c3_415 4807 21378 513 170 166 −12 Acyrthosiphon P46184 (de:50s ribosomal protein 130) kondoi endosymbiont 2915905_c3_416 4808 21379 438 145 478 −45 Acyrthosiphon P46185 (de:50s ribosomal protein 115) kondoi endosymbiont 22844827_c3_417 4809 21380 1329 442 1498 −153 Escherichia P03844 (de:preprotein translocase secy subunit) coli 31384688_c3_418 4810 21381 624 207 785 −78 Escherichia C23807 (cl:escherichia coli ribosomal protein s4) coli (mp:73 min) 32129455_c3_429 4811 21382 216 71 207 −17 Klebsiella Contig354A GTC ORF with score 207 to: (ai:7000772953) pneumoniae (or:Pseudomonas aeruginosa) 32626708_c3_430 4812 21383 1473 490 120 −4 Homo sapiens Q15428 (sr:,human) (de:spliceosome associated protein 62 (sap 62) (sf3a66)) 12585306_c3_431 4813 21384 411 136 551 −53 Pseudomonas P40947 (de:single-strand binding protein (ssb) (helix- aeruginosa destabilizing protein)) 16667665_c3_434 4814 21385 804 267 122 −6 Klebsiella Contig558A GTC ORF with score 411 to: (ai:7000841160) pneumoniae (or:Enterobacter cloacae) 4394818_c3_444 4815 21386 2922 973 2252 −233 Pseudomonas AF074705 (de:pseudomonas aeruginosa aeruginosa dihydroaeruginoic acid synthetase (pche) andpyochelin synthetase (pchf) genes, complete cds.) (nt:peptide synthetase) 35806416_c3_445 4816 21387 555 184 110 −4 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 16509541_c3_448 4817 21388 783 260 110 −3 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 16270126_c3_449 4818 21389 480 159 95 −4 Homo sapiens S09612 (sr:, man) 22869540_c3_450 4819 21390 804 267 116 −5 mice S50883 (sr:mice macrophage) (de:putative transcription regulator (clone t2, repetitive sequence)(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 35626701_c3_451 4820 21391 954 317 141 −6 Alphaherpes- S04713 (cl:herpesvirus immediate-early protein ie175) virus pseudorabies virus PRV 10629202_f1_1 4821 21392 621 206 722 −71 Escherichia P52082 (de:hypothetical 18.6 kd protein in hyba-exbd coli intergenic region (f164)) 15652268_f1_12 4822 21393 717 238 274 −24 Klebsiella Contig186A GTC ORF with score 274 to: (ai:7000772988) pneumoniae (or:Pseudomonas aeruginosa) 14455433_f1_13 4823 21394 333 110 384 −35 Haemophilus P44359 (de:50s ribosomal protein 121) influenzae 13130092_f1_14 4824 21395 183 60 92 −5 Klebsiella Contig484A GTC ORF with score 92 to: (ai:7000772990) pneumoniae (or: Pseudomonas aeruginosa) 16612942_f1_16 4825 21396 1629 542 673 −66 Escherichia P07005 (ec:2.7.2.11) (de:glutamate 5-kinase, (gamma- coli glutamyl kinase) (gk)) 13018928_f1_19 4826 21397 723 240 98 −2 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 25489807_f1_22 4827 21398 2844 947 4109 −9999 Pseudomonas P18330 (ec:6.1.1.5) (de:(ilers)) fluorescens 9885081_f1_25 4828 21399 1107 368 1079 −109 Escherichia P22565 (de:lytb protein) coli 6510806_f1_45 4829 21400 1014 337 928 −93 Pseudomonas P33640 (de:sfhb protein homolog (fragment)) aeruginosa 12391456_f1_48 4830 21401 789 262 122 −5 Caenorhabditis Z70756 (de:caenorhabditis elegans cosmid t06e4, elegans complete sequence.) (nt:similar to collagen) 32132267_f1_49 4831 21402 897 298 111 −4 Rhodobacter X87256 (de:r. sphaeroides hisbd, hish, hisa, hisf and sphaeroides hise genes.) 26698885_f2_56 4832 21403 456 151 12364758_f2_57 4833 21404 657 218 550 −53 Escherichia S56432 (cl:peptidylprolyl cis-trans-isomerase domain coli homology) (ec:5.2.1.8) 7282266_f2_59 4834 21405 1158 385 431 −41 Klebsiella Contig549A GTC ORF with score 831 to: (ai:7000787523) pneumoniae (or:Pseudomonas aeruginosa) 14105283_f2_67 4835 21406 240 79 126 −7 Cyano- P73071 (sr:pcc 6803,) (ec:2.7.2.11) (de:glutamate 5- bacterium kinase, (gamma-glutamyl kinase) (gk)) synechocystis 16896032_f2_70 4836 21407 1602 533 2028 −210 Salmonella P37169 (de:virulence factor mvin) choleraesuis serotype typhimurium 35635417_f2_71 4837 21408 1035 344 1157 −117 Pseudomonas P22990 (ec:2.7.1.26:2.7.7.2) (de:synthetase)) fluorescens 34073837_f2_78 4838 21409 645 214 702 −69 Pseudomonas P17942 (ec:3.4.23.36) (de:peptidase) (signal peptidase fluorescens ii) (spase ii)) 25679183_f2_80 4839 21410 441 146 98 −2 Homo sapiens AB002306 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0308 gene, partial cds.) 20984783_f2_83 4840 21411 1842 613 36223558_f2_91 4841 21412 744 247 278 −24 Pseudomonas P33642 (de:hypothetical protein in pilr 3′region (orfz) aeruginosa (fragment)) 32320462_f2_102 4842 21413 2580 859 3077 −9999 Escherichia P03815 (de:clpb protein (heat shock protein f84.1)) coli 36024140_f3_117 4843 21414 234 77 22400276_f3_122 4844 21415 261 86 332 −30 Escherichia JS0767 (cl:escherichia coli ribosomal protein coli 127:eubacterial ribosomal protein 127 homology) (mp:69 min) 6269781_f3_123 4845 21416 1248 415 1180 −120 Haemophilus P44915 (de:hypothetical 43.4 kd gtp-binding protein influenzae hi0877) 22745205_f3_126 4846 21417 834 277 101 −5 Lycopersicon S14977 (sr:, tomato) esculentum 2989138_f3_132 4847 21418 1962 653 2586416_f3_133 4848 21419 810 269 104 −3 Herpesvirus U23857 (fn:binds to orip to permit replication of the) papio (de:herpesvirus papio brrf2 homolog gene, partial cds, ebnal, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homologgene, partial cds.) (nt:similar to ebnal of epstein-barr v . . . 34510942_f3_134 4849 21420 669 222 601 −58 Pseudomonas P21863 (ec:5.2.1.8) (de:(ec 5.2.1.8) (ppiase) fluorescens (rotamase)) 861686_f3_135 4850 21421 408 135 144 −10 Klebsiella Contig408A GTC ORF with score 144 to: (ai:7000773111) pneumoniae (or:Pseudomonas aeruginosa) 31741717_f3_136 4851 21422 594 197 96 −3 Klebsiella Contig459A GTC ORF with score 96 to: (ai:7000773112) pneumoniae (or:Pseudomonas aeruginosa) 3241333_f1_147 4852 21423 1260 419 1858 −192 Pseudomonas L48934 (gn:dada*) (de:pseudomonas aeruginosa aeruginosa (isolate pric351) pilr gene, 3′ end of cds,dada*, fimt, fimu and pilv genes, complete cds.) (nt:homolgous to d-amino acid dehydrogenase enzyme) 14651068_f3_148 4853 21424 1467 488 185 −13 Aeromonas U56832 (de:aeromonas hydrophila fk506 binding hydrophila protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 10035005_f3_151 4854 21425 1590 529 258 −22 Klebsiella Contig363A GTC ORF with score 258 to: (ai:7000773127) pneumoniae (or:Pseudomonas aeruginosa) 11806933_f3_152 4855 21426 1704 567 687 −67 Escherichia P33644 (de:hypothetical 26.3 kd protein in sfhb-clpb coli intergenic region) 14086006_f3_161 4856 21427 1107 368 920 −92 Escherichia P77316 (de:intergenic region) coli 16218881_c1_165 4857 21428 951 316 141 −7 Lactobacillus X78999 (de:l. leichmannii pyrc gene.) leichmannii 16305406_c1_169 4858 21429 819 272 242 −21 Candida CONTIG554 GTC ORF with score 242 to: (ai:7000773145) albicans 7 (or:Pseudomonas aeruginosa) 34378766_c1_170 4859 21430 1116 371 598 −58 Acinetobacter CONTIG212 GTC ORF with score 598 to: (ai:7000773146) baumannii C (or:Pseudomonas aeruginosa) 31773442_c1_171 4860 21431 186 61 29864531_c1_173 4861 21432 1041 346 368 −34 Klebsiella Contig363A GTC ORF with score 911 to: (ai:7000820913) pneumoniae (or:Enterobacter cloacae) 25913918_c1_174 4862 21433 765 254 109 −4 Caenorhabditis Z68219 (de:caenorhabditis elegans cosmid t05a1, elegans complete sequence.) (nt:similar to collagen; cdna est cemse21f comes from) 11883532_c1_179 4863 21434 465 154 160 −11 Caenorhabditis Q09455 (de:putative cuticle collagen c09g5.4) elegans 16695216_c1_180 4864 21435 924 307 200 −13 Epstein-Barr S27923 virus 16500043_c1_182 4865 21436 798 265 173 −10 herpes simplex Z86099 (de:herpes simplex virus type 2 (strain hg52), virus type 2 complete genome.) HSV-2 26848418_c1_183 4866 21437 576 191 868 −87 Pseudomonas L48934 (de:pseudomonas aeruginosa (isolate pric351) aeruginosa pilr gene, 3′ end of cds,dada*, fimt, fimu and pilv genes, complete cds.) (nt:contains pre- pilin like leader sequence; involved) 34613282_c1_184 4867 21438 525 174 830 −83 Pseudomonas L48934 (de:pseudomonas aeruginosa (isolate pric351) aeruginosa pilr gene, 3′ end of cds,dada*, fimt, fimu and pilv genes, complete cds.) (nt:contains pre- pilin like leader sequence; involved) 13791692_c1_186 4868 21439 387 128 97 −5 Aspergillus Contig9422 GTC ORF with score 163 to: (ai:108708) fumigatus (or:Autographa californica nucleopolyhedrovirus) (sr:,acmnpv) (de:hypothetical 24.1 kd protein in lef4-p33 intergenic region) 12992936_c1_189 4869 21440 645 214 654 −64 Pseudomonas S72644 aeruginosa 31697657_c1_195 4870 21441 408 135 599 −58 Pseudomonas S72634 aeruginosa 21692951_c1_197 4871 21442 417 138 234 −20 Klebsiella Contig408A GTC ORF with score 496 to: (ai:7000818167) pneumoniae (or:Enterobacter cloacae) 14345428_c1_198 4872 21443 537 178 281 −25 Klebsiella Contig408A GTC ORF with score 496 to: (ai:7000818167) pneumoniae (or:Enterobacter cloacae) 22000401_c1_202 4873 21444 2571 856 831 −83 Klebsiella Contig408A GTC ORF with score 1008 to: pneumoniae (ai:7000818161) (or:Enterobacter cloacae) 6384452_c1_204 4874 21445 795 264 126 −5 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 26582061_c1_209 4875 21446 354 117 263 −23 Vibrio cholerae AJ002395 (de:vibrio cholerae nhar, hlyu, mvin, and rpst genes.) (nt:homologue of rpst encoding a ribosomal protein of) 13160325_c1_211 4876 21447 1308 435 228 −19 Enterobacter CONTIG275 GTC ORF with score 470 to: (ai:7501746207) cloacae (or:Klebsiella pneumoniae) 12206961_c1_214 4877 21448 1026 341 831 −83 Escherichia P19641 (ec:2.5.1.—) (de:synthetase)) coli 13022818_c1_219 4878 21449 423 140 108 −5 Saccharomyces P32323 (sr:,baker′s yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 10260202_c1_222 4879 21450 651 216 345 −32 Klebsiella Contig539A GTC ORF with score 345 to: (ai:7000773198) pneumoniae (or:Pseudomonas aeruginosa) 1283143_c2_224 4880 21451 588 195 152 −11 Enterobacter CONTIG502 GTC ORF with score 476 to: (ai:7501754470) cloacae (or:Klebsiella pneumoniae) 16140790_c2_225 4881 21452 1077 358 872 −87 Bordetella S66937 (de:orf1 . . . orf3 {transposon-like sequence} pertussis (bordetella pertussis,genomic, 3 genes, 2300 nt).) 16114687_c2_226 4882 21453 357 118 101 −5 Klebsiella Contig523A GTC ORF with score 181 to: (ai:175260) pneumoniae (or:Volvox carteri) 20433257_c2_227 4883 21454 564 187 137 −8 mice|C57BL AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 13172915_c2_229 4884 21455 354 117 116 −7 Enterobacter CONTIG435 GTC ORF with score 116 to: (ai:7000773205) cloacae (or:Pseudomonas aeruginosa) 5214677_c2_231 4885 21456 906 301 183 −14 Enterobacter CONTIG374 GTC ORF with score 183 to: (ai:7000773207) cloacae (or:Pseudomonas aeruginosa) 25447836_c2_233 4886 21457 1071 356 1753 −180 Pseudomonas P33641 (de:hypothetical 38.5 kd protein in pils aeruginosa 5′region (orfy) 14660830_c2_234 4887 21458 402 133 12682013_c2_237 4888 21459 1986 661 2241 −232 Pseudomonas S33674 (cl:response regulator homology:rna aeruginosa polymerase sigma factor interaction domain homology) 33725683_c2_242 4889 21460 1434 477 1396 −143 Pseudomonas S72643 aeruginosa 31270441_c2_250 4890 21461 963 320 117 −4 Actinomyces S20590 (cc:3.2.1.18) viscosus 10244706_c2_255 4891 21462 555 184 146 −10 Acinetobacter CONTIG229 GTC ORF with score 146 to: (ai:7000773231) baumannii C (or:Pseudomonas aeruginosa) 11196916_c2_269 4892 21463 1620 539 439 −42 Enterobacter CONTIG325 GTC ORF with score 439 to: (ai:7000773245) cloacae (or:Pseudomonas aeruginosa) 29814068_c2_276 4893 21464 1554 517 16141283_c2_277 4894 21465 489 162 101 −2 Homo sapiens S57132 (sr:human placenta) (de:col16a1=type xvi collagen alpha 1 chain (human, placenta, mrnapartial, 3720 nt).) (nt:this sequence comes from FIG. 2; alpha 1 (xvi)) 31922956_c2_279 4895 21466 408 135 111 −5 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 15910031_c3_282 4896 21467 420 139 434 −41 Enterobacter CONTIG502 GTC ORF with score 436 to: (ai:7000784484) cloacae (or:Pseudomonas aeruginosa) 24689192_c3_286 4897 21468 2970 989 556 −53 Enterobacter CONTIG374 GTC ORF with score 605 to: (ai:7501737323) cloacae (or:Klebsiella pneumoniae) 4431952_c3_287 4898 21469 612 203 110 −3 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) type EVH-1 32507080_c3_291 4899 21470 1791 596 2661 −277 Pseudomonas P33639 (ec:2.7.3.—) (de:sensor protein pils,) aeruginosa 34507840_c3_293 4900 21471 408 135 134 −8 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 22837758_c3_298 4901 21472 1182 393 953 −96 Pseudomonas L48934 (de:pseudomonas aeruginosa (isolate pric351) aeruginosa pilr gene, 3′ end of cds,dada*, fimt, fimu and pilv genes, complete cds.) (nt:involved in type 4 fimbrial biogenesis; contains) 14975840_c3_300 4902 21473 672 223 216 −18 Pseudomonas S72644 aeruginosa 22786391_c3_301 4903 21474 3573 1190 5075 −9999 Pseudomonas S72645 aeruginosa 15898510_c3_302 4904 21475 771 256 721 −71 Pseudomonas S54700 aeruginosa 30744381_c3_304 4905 21476 321 106 139 −10 Enterobacter CONTIG332 GTC ORF with score 139 to: (ai:7000773280) cloacae (or:Pseudomonas aeruginosa) 14932825_c3_305 4906 21477 1008 335 201 −16 Enterobacter CONTIG332 GTC ORF with score 502 to: (ai:7501742363) cloacae (or:Klebsiella pneumoniae) 22130155_c3_313 4907 21478 1548 515 114 −3 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 32444436_c3_322 4908 21479 993 330 94 −4 longfin squid S56117 (sr:, longfin squid) 10162563_c3_324 4909 21480 267 88 22275837_c3_326 4910 21481 2139 712 955 −96 Acetobacter Q03318 (de:alcohol dehydrogenase cytochrome c polyoxogenes subunit precursor) 25583290_c3_327 4911 21482 1401 466 216 −17 Enterobacter CONTIG165 GTC ORF with score 216 to: (ai:7000773303) cloacae (or:Pseudomonas aeruginosa) 21504591_f1_5 4912 21483 810 269 31354181_f1_7 4913 21484 1164 387 834 −83 Vibrio P19906 (ec:2.7.3.—) (de:nitrogen regulation protein alginolyticus ntrb,) 16539658_f2_14 4914 21485 312 103 107 −4 Gallus gallus S27939 (sr:,chicken) domesticus 14660313_f2_15 4915 21486 786 261 2605438_f2_22 4916 21487 1041 346 166 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia(mia) castellanii gene, complete cds.) (nt:myosin-i) 31817711_f1_25 4917 21488 1548 515 130 −4 no gb U52064 (de:kaposi's sarcoma-associated herpes-like taxonomy virus orf73 homolog gene,complete cds.) match (nt:herpesvirus saimiri orf73 homolog) 30569381_f3_28 4918 21489 1488 495 92 −1 Homo sapiens AF035528 (fn:inhibitor of bmp signaling) (sr:human) (de:homo sapiens smad6 mrna, complete cds.) (nt:smad family member) 16688517_f3_29 4919 21490 402 133 98 −3 Alphaherpes- B40505 virus pseudorabies virus PRV 13102077_f3_30 4920 21491 1500 499 1644 −169 Salmonella P41789 (de:nitrogen regulation protein nr(i)) choleraesuis serotype typhimurium 4426902_c1_43 4921 21492 1353 450 93 −2 Aspergillus Contig8315 GTC ORF with score 113 to: (ai:7000779042) fumigatus (or:Pseudomonas aeruginosa) 16100083_c2_46 4922 21493 1620 539 200 −15 Aeromonas U56832 (de:aeromonas hydrophila fk506 binding hydrophila protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 16583157_c2_50 4923 21494 2172 724 338 −27 Escherichia P75783 (de:hypothetical 86.8 kd protein in ding-glnq coli intergenic region) 26380342_c3_51 4924 21495 687 228 474 −45 Coxiella Q45968 (de:transposase for insertion sequence element burnetii is1111a) 11041287_c3_53 4925 21496 504 167 360 −33 Klebsiella Contig294A GTC ORF with score 444 to: (ai:7000845216) pneumoniae (or:Enterobacter cloacae) 13101433_f1_5 4926 21497 915 305 1168 −118 Alteromonas AB009654 (sr:alteromonas sp. (strain:ke10) dna) sp. (de:alteromonas sp. dna for aldehyde dehydrogenase, complete cds.) 31901466_f2_6 4927 21498 2211 736 254 −21 Klebsiella Contig535A GTC ORF with score 636 to: (ai:7000826275) pneumoniae (or:Enterobacter cloacae) 14947567_12_7 4928 21499 252 83 110 −5 Volvox carteri P21997 (de:sulfated surface glycoprotein 185 (ssg 185)) 22136566_f3_13 4929 21500 435 144 102 −3 Gallus gallus I50463 (cl:unassigned ser/thr or tyr-specific protein domesticus kinases:protein kinase homology) (sr:, chicken) 32704158_f3_14 4930 21501 432 144 98 −5 Klebsiella Contig471A GTC ORF with score 160 to: (ai:7000758711) pneumoniae (or:Pseudomonas aeruginosa) 31735174_c1_15 4931 21502 951 316 180 −13 Azospirillum X70360 (de:a. brasilense carr gene.) brasilense 31803956_c2_23 4932 21503 1278 426 231 −16 Rana AB015440 (sr:rana catesbeiana cdna to mrna) (de:rana catesbeiana catesbeiana mrna for alpha 1 type i collagen, complete cds.) 21769026_c3_26 4933 21504 1878 626 1118 −113 Ralstonia P28614 (de:acetoin catabolism regulatory protein) eutropha 31753268_f1_5 4934 21505 1665 554 22760066_f1_7 4935 21506 1356 451 145 −7 Klebsiella Contig363A GTC ORF with score 442 to: (ai:7000820879) pneumoniae (or:Enterobacter cloacae) 32053805_f1_8 4936 21507 933 310 106 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 12011461_f1_17 4937 21508 939 312 192 −13 Homo sapiens S80905 (sr:human subject “r.s.” peripheral blood leukocytes) (de:prb2 (prb21 con1+)=con1 {exon 3} (human, peripheral bloodleukocytes, subject ‘r.s.’, genomic mutant, 1179 nt).) (nt:salivary concanavalin-a binding protein; method:) 12708563_f1_18 4938 21509 1488 495 290 −25 Ralstonia P40852 (ec:3.1.3.18) (de:phosphoglycolate eutropha phosphatase, chromosomal,) 13022905_f1_19 4939 21510 1749 582 4426417_f1_22 4940 21511 1224 407 745 −74 Escherichia P19933 (de:sodium/glutamate symport carrier protein coli (glutamate permease)) 33724091_f1_23 4941 21512 1131 376 356 −32 Aquifex H70302 aeolicus 15130131_f1_32 4942 21513 543 180 104 −3 Actinomyces S20590 (ec:3.2.1.18) viscosus 6453966_f1_33 4943 21514 1908 635 146 −7 Rattus M64793 (sr:rat (sprague-dawley) liver dna) (de:rat norvegicus salivary proline-rich protein (rp15) gene, complete cds.) 31723325_f2_35 4944 21515 522 173 172 −13 Klebsiella Contig344A GTC ORF with score 172 to: (ai:7000773424) pneumoniae (or:Pseudomonas aeruginosa) 14347918_f2_36 4945 21516 996 331 131 −5 Sus scrofa I47141 (sr:, domestic pig) domestica 10275665_f2_40 4946 21517 822 273 105 −2 cabbage looper AF000606 (sr:cabbage looper) (de:trichoplusia ni insect intestinal mucin iim22 mrna, complete cds.) 2072958_f2_41 4947 21518 855 284 165 −11 Klebsiella Contig412A GTC ORF with score 523 to: (ai:7000825143) pneumoniae (or:Enterobacter cloacae) 3338206_f2_52 4948 21519 528 175 122 −8 Enterobacter CONTIG502 GTC ORF with score 308 to: (ai:7501793461) cloacae (or:Klebsiella pneumoniae) 2477080_f2_53 4949 21520 642 213 122 −7 Enterobacter CONTIG502 GTC ORF with score 373 to: (ai:7501793462) cloacae (or: Klebsiella pneumoniae) 12750156_f2_54 4950 21521 1317 438 588 −57 Aquifex G70352 aeolicus 16995886_f2_55 4951 21522 816 271 799 −79 Escherichia P17993 (ec:2.1.1.64)(de:methyltransferase)) coli 14181955_f2_58 4952 21523 864 287 594 −58 Escherichia P31808 (ec:1.—.—.—) (de:(ec 1.—.—.—)) coli 3212713_f2_59 4953 21524 648 215 168 −12 Escherichia P76268 (de:transcriptional regulator kdgr) coli 6929081_f2_60 4954 21525 951 316 404 −37 Klebsiella P19452 (ec:3.5.3.8) (de:(histidine utilization protein g) pneumoniae (fragment)) aerogenes 22914780_f2_70 4955 21526 1071 356 214 −17 Klebsiella Contig460A GTC ORF with score 605 to: (ai:7000817234) pneumoniae (or:Enterobacter cloacae) 24650842_f2_71 4956 21527 1758 585 456 −43 Klebsiella Contig460A GTC ORF with score 572 to: (ai:7000817687) pneumoniae (or:Enterobacter cloacae) 12994583_f2_72 4957 21528 909 302 1402 −143 Pseudomonas AF029673 (fn:hex regulon repressor (includes zwf, eda, aeruginosa edd,) (de:pseudomonas aeruginosa hexr (hexr), glucose-6-phosphate 1-dehydrogenase (zwf), and 2-keto-3-deoxy-6- phosphogluconatealdolase (eda) genes, complete cds.) (nt:similar to rpir) 33863183_f2_73 4958 21529 300 99 164 −12 Klebsiella Contig500A GTC ORF with score 164 to: (ai:7000773462) pneumoniae (or:Pseudomonas aeruginosa) 23672330_f2_74 4959 21530 1254 418 16273891_f3_76 4960 21531 363 120 219 −18 Klebsiella Contig344A GTC ORF with score 272 to: (ai:117022) pneumoniae (or:Escherichia coli) (de:very hypothetical 15.8 kd protein in rpsa 5′region.) 29397563_f3_79 4961 21532 438 145 139 −9 Rattus B48013 (cl:proline-rich protein) (sr:, norway rat) norvegicus 16289805_f3_82 4962 21533 234 77 95 −4 Pisum sativum Y11824 (sr:pea) (de:p. sativum mrna for hypothetical protein.) (nt:expressed in chloroplast) 35252258_f3_83 4963 21534 1125 374 220 −18 Klebsiella Contig466A GTC ORF with score 261 to: (ai:7000833372) pneumoniae (or:Enterobacter cloacae) 31894003_f3_84 4964 21535 2886 961 218 −42 Mycobacterium X84077 (de:m. smegmatis gyrb and gyra genes.) (nt:val smegmatis start codon) 16504191_f3_88 4965 21536 432 143 177 −13 Methano- O27549 (de:hypothetical protein mth1505) bacterium thermo autotrophicum 14932183_f3_91 4966 21537 393 130 105 −5 mice|C57BL/ X07244 (sr:house mouse) (de:mouse mrna for neural 6xCBA/ cell adhesion molecule (ncam-180).) (nt:ncam- CaJ hybrid 180 (278 aa)) 24110033_f3_96 4967 21538 387 128 142 −9 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10281331_f3_97 4968 21539 1620 539 109 −3 Canis A45195 (cl:guanylate cyclase catalytic domain familiaris homology) (sr:, dog) 12523961_f3_99 4969 21540 765 254 123 −8 Aspergillus Contig3226 GTC ORF with score 108 to: (ai:334261) fumigatus (or:Gossypium hirsutum) (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna. completecds.) 489583_f3_100 4970 21541 2007 668 108 −5 Cyano- S74508 (cl:mutt domain homology) (sr:pcc 6803,,pcc bacterium 6803) (sr:pcc 6803,) synechocystis 5114708_f3_102 4971 21542 792 263 142 −7 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 31926966_c1_111 4972 21543 1164 387 253 −21 Escherichia P39173 (de:unknown protein from 2d-page (spots coli t26/pr37)) 5319580_c1_116 4973 21544 363 120 119 −8 Klebsiella Contig460A GTC ORF with score 119 to: (ai:7000773505) pneumoniae (or:Pseudomonas aeruginosa) 12370333_c1_117 4974 21545 801 266 243 −20 Helicobacter F64657 pylori 35632081_c1_118 4975 21546 276 91 99 −4 Myxococcus AF055904 (de:myxococcus xanthus acetylornithine xanthus deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 13958302_c1_121 4976 21547 780 259 154 −8 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 13913207_c1_123 4977 21548 1011 336 129 −5 Achromobacter L81125 (sr:pseudomonas sp (strain imt37) dna) georgio- (de:pseudomonas sp. (strain imt37) politanum monooxygenase subunit gene, completecds.) 1730063_c1_124 4978 21549 1602 533 124 −4 no gb U93872 (sr:kaposi's sarcoma-associated herpesvirus - taxonomy human herpesvirus 8) (de:kaposi's sarcoma- match associated herpesvirus glycoprotein m, dnareplication protein, glycoprotein, dna replication protein, fliceinhibitory protein and v-cyclin genes. . . . 29924157_c1_132 4979 21550 573 190 123 −8 Aspergillus Contig2938 GTC ORF with score 123 to: (ai:7000773521) fumigatus (or:Pseudomonas aeruginosa) 6767258_c1_137 4980 21551 894 297 98 −2 Homo sapiens L02867 (sr:homo sapiens (tissue library: 1-zapii) cdna to mrna) (de:homo sapiens 62 kda paraneoplastic antigen mrna, 3′ end.) (nt:62 kda) 32282066_c1_139 4981 21552 720 239 113 −4 Aspergillus Contig8029 GTC ORF with score 318 to: (ai:120145) fumigatus (or:Bos taurus) (sr:, cattle) 22158301_c1_140 4982 21553 2046 681 1682 −173 Pseudomonas P27603 (sr:pseudomonas perfectomarina) stutzeri (ec:5.4.99.5:4.2.1.51) (de:(ec 4.2.1.51) (pdt) (p- protein)) 31692580_c1_143 4983 21554 2349 782 951 −95 Cyano- Q59975 (sr:pcc 6803,) (ec:2.5.1.19) (de:(3- bacterium enolpyruvylshikimate-5-phosphate synthase) synechocystis (epsp synthase)) 31851682_c2_153 4984 21555 1215 404 93 −1 Drosophila P49456 (sr:,fruit fly) (de:tropomyosin 1, fusion protein melanogaster 34) 494790_c2_154 4985 21556 1206 401 749 −74 Escherichia P37765 (de:hypothetical 32.7 kd protein in trpl-btur coli intergenic region (orf4)) 14333576_c2_158 4986 21557 462 153 117 −6 Pseudomonas M32077 (sr:p. aeruginosa (strain pao, isolate pa02003) aeruginosa dna, from patien) (de:p. aeruginosa exopolysaccharide alginate regulatory protein (algpand algq) genes, complete cds.) (nt:alginate regulatory protein p; (put.); putative) 30332568_c2_161 4987 21558 558 185 112 −4 Caenorhabditis Z75539 (de:caenorhabditis elegans cosmid f28c1, elegans complete sequence.) (nt:predicted using genefinder; cdna est embl:c13354) 15755378_c2_173 4988 21559 2862 953 4612 −9999 Pseudomonas P48372 (ec:5.99.1.3) (de:dna gyrase subunit a,) aeruginosa 32713168_c2_174 4989 21560 1173 390 1074 −108 Yersinia P19689 (ec:2.6.1.52) (de:phosphoserine enterocolitica aminotransferase,) 31916467_c2_183 4990 21561 396 131 99 −3 Sorangium U24241 (fn:involved in soraphen a biosynthesis) cellulosum (de:sorangium cellulosum soraphen a polyketide synthase gene, partialcds including the ketoreductase, acyl carrier protein,beta- ketoacyl synthase acyltransferase, and dehydratase domains.) (nt:si . . . 14664838_c3_185 4991 21562 1149 382 1894 −195 Pseudomonas S42207 aeruginosa 32289693_c3_187 4992 21563 1332 443 178 −13 Enterobacter CONTIG322 GTC ORF with score 178 to: (ai:7000773576) cloacae (or:Pseudomonas aeruginosa) 12929561_c3_188 4993 21564 1476 491 2552 −265 Pseudomonas AF029673 (ec:1.1.1.49) (de:pseudomonas aeruginosa aeruginosa hexr (hexr), glucose-6-phosphate1- dehydrogenase (zwf), and 2-keto-3-deoxy-6- phosphogluconatealdolase (eda) genes, complete cds.) 13145811_c3_190 4994 21565 1131 376 1117 −113 Pseudomonas AF029673 (ec:4.1.2.14) (de:pseudomonas aeruginosa aeruginosa hexr (hexr), glucose-6-phosphate 1- dehydrogenase (zwf), and 2-keto-3-deoxy-6- phosphogluconatealdolase (eda) genes, complete cds.) 32694556_c3_191 4995 21566 837 278 114 −4 Pseudomonas A35630 aeruginosa 12769808_c3_196 4996 21567 2874 957 182 −13 Klebsiella Contig559A GTC ORF with score 182 to: (ai:7000773585) pneumoniae (or:Pseudomonas aeruginosa) 16257283_c3_198 4997 21568 726 241 268 −23 Enterobacter CONTIG506 GTC ORF with score 268 to: (ai:7000773587) cloacae (or:Pseudomonas aeruginosa) 13087942_c3_199 4998 21569 1932 643 246 −18 Aquifex C70481 aeolicus 13067293_c3_200 4999 21570 723 240 558 −54 Aquifex C70481 aeolicus 25519692_c3_207 5000 21571 1269 422 1023 −103 Methylo- O07131 (cc:2.6.1.9) (de:phosphate transaminase)) bacillus flagellatum 35261006_c3_212 5001 21572 1167 388 675 −66 Escherichia X00785 (de:e. coli rpsa operon leader sequence.) coli (nt:urf p25) 12985718_f1_4 5002 21573 1047 348 155 −8 African clawed U85969 (sr:african clawed frog) (de:xenopus laevis frog middle molecular weight neurofilament proteinnf-m(1) mrna, complete cds.) (nt:neuronal intermediate filament protein; duplicated) 31349183_f1_12 5003 21574 981 326 172 −12 Rhizobium sp. S28675 31446037_f1_13 5004 21575 2223 740 289 −25 Klebsiella Contig460A GTC ORF with score 408 to: (ai:7000817235) pneumoniae (or:Enterobacter cloacae) 10016055_f1_16 5005 21576 1371 456 24781326_f1_23 5006 21577 648 215 434 −41 Escherichia U24198 (de:escherichia coli ecor28 (ycid) gene, coli partial cds, and (ycic), (ycib), (ycia), membrane protein (tonb), (ycii), putative potassiumchannel (kch), and cardiolipin synthase (cls) genes, complete cds.) 644511_f1_24 5007 21578 453 150 115 −6 Caenorhabditis U55373 (de:caenorhabditis elegans cosmid f26f12.) elegans (nt:similar to cuticular collagen; coded for by c.) 3339408_f1_25 5008 21579 327 108 91 −5 Aspergillus Contig9726 GTC ORF with score 137 to: (ai:393577) fumigatus (or:Mus musculus) (sr:house mouse) (de:mus musculus mena protein (mena) mrna, complete cds.) (nt:mammalian enabled; binds to zyxin, vinculin and) 14735216_f1_26 5009 21580 1431 476 146 −6 Drosophila AF053091 (sr:fruit fly) (de:drosophila melanogaster melanogaster eyelid (eld) mrna, complete cds.) (nt:bright family member) 31432881_f1_29 5010 21581 429 142 117 −7 mice|C57BL/ D29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 31378957_f1_30 5011 21582 510 169 149 −9 Caulobacter M69228 (fn:transcription activator) (sr:caulobacter crescentus crescentus (strain cb15) dna) (de:c. crescentus flagellar gene promoter region.) (nt:putative) 12976457_f1_33 5012 21583 519 172 172 −13 Klebsiella Contig559A GTC ORF with score 172 to: (ai:7000773635) pneumoniae (or:Pseudomonas aeruginosa) 11192887_f1_34 5013 21584 1599 532 31379825_f1_35 5014 21585 1860 619 544 −52 Aquifex H70432 aeolicus 12305388_f1_36 5015 21586 1581 526 129 −6 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 16142555_f1_44 5016 21587 1251 416 4786306_f1_45 5017 21588 924 307 145 −6 eqine AF030027 (fn:very large tegument protein) (de:equine herpesvirus herpesvirus 4 strain ns80567, complete type 4-EHV-4 genome.) (nt:counterpart of hsv-1 gene ul36 vzv gene 22) 12979708_f1_52 5018 21589 1029 342 199 −13 Micrococcus JQ0405 luteus 12632001_f1_53 5019 21590 825 274 221 −18 Brady- Y10223 (ec:3.1.1.24) (de:b. japonicum pcab, pcad & rhizobium japonicum 12986280_f1_54 5020 21591 1962 653 118 −4 Aspergillus Contig8669 GTC ORF with score 124 to: (ai:5500701392) fumigatus (or:Nephila clavipes) (de:nephila clavipes minor ampullate silk protein misp1 mrna, partialcds.) 34158131_f1_55 5021 21592 504 167 35355291_f1_57 5022 21593 1260 419 34480066_f1_62 5023 21594 531 176 98 −5 Klebsiella Contig499A GTC ORF with score 98 to: (ai:7000773664) pneumoniae (or:Pseudomonas aeruginosa) 10282691_f1_65 5024 21595 384 127 2526026_f1_67 5025 21596 1506 501 24876651_f1_68 5026 21597 999 332 186 −12 Homo sapiens Y07867 (sr:human) (de:h. sapiens mrna for pirin, isolate 1.) 13683427_f1_69 5027 21598 357 118 109 −5 Myxococcus AF055904 (de:myxococcus xanthus acetylornithine xanthus deacetylase (arge) gene, complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 16897905_f1_70 5028 21599 450 149 135 −8 Caenorhabditis Z81138 (de:caenorhabditis elegans cosmid w05b2, elegans complete sequence.) (nt:protein predicted using genefinder; preliminary) 4813278_f2_72 5029 21600 822 273 298 −26 Escherichia P18196 (de:cell division inhibitor mine) coli 19633256_f1_73 5030 21601 678 225 131 −8 Klebsiella Contig549A GTC ORF with score 95 to: (ai:7500985756) pneumoniae (or:Plasmodium chabaudi) (de:plasmodium chabaudi circumsporozoite protein (cs) gene, partialcds.) 20952_f1_74 5031 21602 255 84 256 −22 Escherichia P18198 (de:cell division topological specificity factor) coli 36536307_f1_80 5032 21603 771 256 186 −15 Klebsiella Contig558A GTC ORF with score 186 to: (ai:7000773682) pneumoniae (or:Pseudomonas aeruginosa) 22367755_f1_81 5033 21604 1149 382 881 −88 Enterococcus CONTIG031 GTC ORF with score 881 to: (ai:7000773683) faecium C (or:Pseudomonas aeruginosa) 32555416_f1_82 5034 21605 864 287 392 −37 Enterococcus CONTIG013 GTC ORF with score 392 to: (ai:7000773684) faecium C (or:Pseudomonas aeruginosa) 11175805_f1_84 5035 21606 837 278 277 −24 Campylobacter AJ000750 (de:campylobacter jejuni malf gene, partial.) jejuni 5102313_f1_96 5036 21607 1068 355 121 −5 Archaeoglobus G69278 fulgidus 24475433_f2_101 5037 21608 1269 422 422 −40 Klebsiella Contig471A GTC ORF with score 428 to: (ai:7000787132) pneumoniae (or:Pseudomonas aeruginosa) 16979167_f2_104 5038 21609 1179 392 153 10 Klebsiella Contig471A GTC ORF with score 153 to: (ai:7000773706) pneumoniae (or:Pseudomonas aeruginosa) 31666416_f2_107 5039 21610 1578 525 103 −5 Klebsiella Contig468A GTC ORF with score 148 to: (ai:7000837343) pneumoniae (or:Enterobacter cloacae) 12929157_f2_112 5040 21611 783 260 126 −6 Aspergillus Contig7774 GTC ORF with score 215 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 25992812_f2_116 5041 21612 1023 340 1674 −172 Pseudomonas P27726 (ec:1.2.1.12) (de:glyceraldehyde 3-phosphate aeruginosa dehydrogenase, (gapdh)) 21770412_f2_119 5042 21613 531 176 184 −13 California red AF023459 (sr:california red abalone) (de:haliotis abalone rufescens lustrin a mrna, complete cds.) (nt:extracellular matrix protein; modular structure) 17066705_f2_124 5043 21614 369 122 349 −30 Escherichia P31070 (de:hypothetical 10.6 kd protein in kch-tonb coli intergenic region) 16151033_f2_126 5044 21615 729 242 499 −48 Escherichia P16244 (de:transcriptional regulatory protein cpxr) coli 14332340_f2_127 5045 21616 330 109 25860091_f2_128 5046 21617 1419 472 393 −36 Pseudomonas Q04804 (ec:2.7.3.—) (de:sensor protein pfes,) aeruginosa 22005166_f2_129 5047 21618 519 172 22714817_f2_131 5048 21619 1536 511 1217 −124 Vibrio D86411 (sr:vibrio alginolyticus (str:138-2) dna) alginolyticus (de:vibrio alginolyticus fmt, fmu, fmv, trka, trkh, orf1 and f219genes, partial and complete cds.) 6144812_f2_132 5049 21620 1170 389 528 −51 Helicobacter JHP1359 (de:hypothetical (conserved with no known pylori function)) (sr:strain j99) 29787830_f2_134 5050 21621 1053 350 225 −18 Aquifex A70433 aeolicus 16022052_f2_140 5051 21622 1617 538 104 −2 mice D84435 (sr:mus sp. (strain:b6cba) 6-8 weeks old female liver cdna to mrna) (de:mus sp. mrna for hmw prekininogen, complete cds.) 16896086_f2_144 5052 21623 831 276 206 −17 Photo- Q51872 (de:probable transcriptional regulator lumq) bacterium leiognathi 22913312_f2_152 5053 21624 1083 360 278 −24 Escherichia P76369 (de:hypothetical transcriptional regulator in coli sbcb-his1 intergenic region) 13177280_f2_157 5054 21625 1875 624 1450 −148 Haemophilus Q57180 (de:hypothetical abc transporter atp-binding influenzae protein hi1051) 13761331_f2_158 5055 21626 429 142 115 −5 Micrococcus JQ0405 luteus 36381291_f2_166 5056 21627 1860 619 91 −2 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus glutamine 6xCBA/ repeat protein-1 mrna, complete cds.) (nt:grp- CaJ hybrid 1) 33721891_f2_167 5057 21628 1233 410 36463216_f2_168 5058 21629 1647 548 31915955_f2_169 5059 21630 807 268 290 −27 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 10397756_f2_170 5060 21631 654 217 305 −27 Homo sapiens Y07867 (sr:human) (de:h. sapiens mrna for pirin, isolate 1.) 3225018_f2_171 5061 21632 1296 431 24691306_f2_174 5062 21633 414 137 110 −6 common PQ0475 (sr:, common tobacco) tobacco 16800902_f2_175 5063 21634 822 273 1046 −106 Escherichia B31877 (cl:cell division inhibitor mind) (mp:26 min) coli 13944780_f2_176 5064 21635 843 280 529 −51 Escherichia P39219 (de:hypothetical 24.9 kd protein in sura-hepa coli intergenic region) 16112533_f2_177 5065 21636 1458 485 736 −73 Mycobacterium Z95151 (de:mycobacterium leprae cosmid b5.) leprae (nt:mlcb5.29, pepx, aminopeptidase, len: 443 aa,) 34105307_f2_186 5066 21637 597 198 96 −2 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine-and) 34274181_f2_187 5067 21638 1311 436 151 −8 Streptomyces AB004855 (sr:streptomyces cyaneus (strain:atcc14921 cyaneus. pk100c) dna) (de:streptomyces cyaneus dna for inhibition of morphologicaldifferentiation, complete cds.) (nt:inhibition of morphological differentiation) 16580392_f2_193 5068 21639 1191 396 124 −7 Klebsiella Contig389A GTC ORF with score 135 to: (ai:7000836094) pneumoniae (or:Enterobacter cloacae) 35330287_f2_194 5069 21640 1824 607 403 −37 Clostridium C41872 acetobutylicum 996057_f3_205 5070 21641 1467 488 16523967_f3_215 5071 21642 234 77 117 −6 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCAB/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 22933441_f3_217 5072 21643 468 155 254 −22 Enterobacter CONTIG138 GTC ORF with score 254 to: (ai:7000773819) (or:Pseudomonas aeruginosa) 36506377_f3_220 5073 21644 540 179 171 −11 equine herpes- AF030027 (fn:very large tegument protein) (de:equine virus type 4 herpesvirus 4 strain ns80567, complete EHV-4 genome.) (nt:counterpart of hsv-1 gene ul36 and vzv gene 22) 16910461_f3_222 5074 21645 711 236 205 −15 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda-1102) virus (type 6/ ie2hom mrna, complete cds.) (nt:similar to the strain Uganda- immediate-early 2 protein of human) 1102) 33724032_f3_223 5075 21646 771 256 353 −32 Enterobacter CONTIG492 GTC ORF with score 353 to: (ai:7000773825) cloacae (or:Pseudomonas aeruginosa) 29948902_f3_234 5076 21647 1056 351 206 −16 Klebsiella Contig420A GTC ORF with score 386 to: (ai:7000840702) pneumoniae (or:Enterobacter cloacae) 12973806_f3_235 5077 21648 528 175 117 −5 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 14926905_f3_237 5078 21649 663 220 108 −3 migratory AJ000390 (sr:migratory locust) (de:locusta migratoria locust mrna for nachr alpha1 subunit.) 4963555_f3_240 5079 21650 843 280 125 −4 Strongylo- S23809 (cl:collagen alpha 2(i) chain:fibrillar collagen centrotus carboxyl-terminal homology) (sr:, purple purpuratus urchin) 5958507_f3_242 5080 21651 393 130 246 −21 Acinetobacter CONTIG227 GTC ORF with score 246 to: (ai:7000773844) baumannii C (or:Pseudomonas aeruginosa) 16269031_f3_243 5081 21652 1608 535 390 −35 Treponema AE001224 (de:treponema pallidum section 40 of 87 of the pallidum complete genome.) (nt:similar to gp:1754638 percent ident: 40.99;) 32120781_f3_245 5082 21653 570 189 129 −6 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 32660331_f3_249 5083 21654 666 221 242 −20 Bacillus P37584 (de:csaa protein) subtilis/ Bacillus globigii 4394092_f3_250 5084 21655 909 302 215 −17 Bacillus Q07835 (de:hypothetical 34.3 kd protein in bglh-wapa subtilis/ intergenic region (orf1)) Bacillus globigii 16933408_f3_256 5085 21656 960 319 101 −1 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 14742037_f3_257 5086 21657 579 192 769 −76 Pseudomonas Q59641 (ec:5.2.1.8) (de:(cyclophilin) (fragment)) aeruginosa 15758341_f3_260 5087 21658 1335 444 10011306_f3_262 5088 21659 1902 633 10157327_f3_263 5089 21660 558 185 325 −29 Enterobacter CONTIG501 GTC ORF with score 325 to: (ai:7000773865) cloacae (or:Pseudomonas aeruginosa) 34510382_f3_273 5090 21661 1557 518 114 −3 Rana AB015440 (sr:rana catesbeiana cdna to mrna) (de:rana catesbeiana catesbeiana mrna for alpha 1 type i collagen, complete cds.) 16100830_f3_279 5091 21662 264 87 98 −5 Aspergillus Contig7774 GTC ORF with score 215 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 30132713_f3_286 5092 21663 981 326 119 −4 Burkholderia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob cepacia (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 15720216_f3_287 5093 21664 1458 485 174 −10 Pyrococcus AP000006 (sr:pyrococcus horikoshii (str:ot3) dna, horikoshii cl:pyrococcus horikoshii) (de:pyrococcus horikoshii ot3 genomic dna, 1166001-1485000 nt. position(6/7).) (nt:similar to :apu049541 percent ident:24.814 in) 29775955_f3_288 5094 21665 1782 593 718 −71 Escherichia P23858 (de:spermidine/putrescine transport atp- coli binding protein pota) 22750705_f3_289 5095 21666 330 109 128 −9 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 155/162.) (nt:rv3661, (mtv025.009), len: 287. unknown but) 22150086_f3_291 5096 21667 2952 983 949 −95 Escherichia P23865 (ec:3.4.21.—) (de:protein)) coli 677263_c1_299 5097 21668 705 234 16814202_c1_300 5098 21669 513 170 125 −7 Plasmodium P08672 (sr:berok,) (de:circumsporozoite protein cynomolgi precursor (cs)) 16412533_c1_305 5099 21670 864 287 133 −5 Alphaherpes- B40505 virus pseudorabies virus PRV 5880430_c1_311 5100 21671 837 278 143 −6 no gb U52064 (de:kaposi's sarcoma-associated herpes-like taxonomy virus or(73 homolog gene,complete cds.) match (nt:herpesvirus saimiri orf73 homolog) 16661683_c1_313 5101 21672 1206 401 9972033_c1_315 5102 21673 882 293 504 −48 Salmonella U69493 (fn:probable repressor protein of gntr family) choleraesuis (de:salmonella typhimurium thij and orf1 serotype genes, partial cds,and phnx,phnw, phnr, typhimurium phns, phnt, phnu and phnv genes, complete cds.) 26650705_c1_326 5103 21674 480 159 227 −19 Escherichia P24187 (ec:2.3.1.—) (de:protein b)) coli 26580142_c1_337 5104 21675 393 130 322 −29 Escherichia P32706 (de:hypothetical 11.7 kd protein in soxr-acs coli intergenic region (f104)) 2906336_c1_340 5105 21676 2415 804 171 −12 Aquifex G70380 aeolicus 15675027_c1_341 5106 21677 243 80 30182092_c1_344 5107 21678 411 136 155 −11 Aspergillus Contig2494 GTC ORF with score 155 to: (ai:7000773946) fumigatus (or:Pseudomonas aeruginosa) 30369641_c1_353 5108 21679 384 127 15719066_c1_360 5109 21680 1584 527 325 −29 Cyano- S76126 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803, ) bacterium synechocystis 12895325_c1_368 5110 21681 507 168 123 −7 Klebsiella Contig543A GTC ORF with score 315 to: (ai:7000802322) pneumoniae (or:Pseudomonas aeruginosa) 36505406_c1_369 5111 21682 930 309 109 −6 Enterobacter CONTIG416 GTC ORF with score 596 to: (ai:7501739524) cloacae (or:Klebsiella pneumoniae) 29942527_c1_376 5112 21683 468 155 333 −30 Escherichia P71300 (de:hypothetical 11.8 kd protein in intf-eaeh coli intergenic region) 3260205_c1_380 5113 21684 414 137 116 −5 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 13025705_c1_385 5114 21685 669 222 110 −4 Schizo- Z95620 (sr:fission yeast) (de:s. pombe chromosome ii saccharomyces cosmid c3d6.) (nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 32619781_c1_394 5115 21686 1197 398 251 −21 Bacillus P35155 (de:hypothetical 22.0 kd protein in ribt-dacb subtilis/ intergenic region (orfx8)) Bacillus globigii 26459755_c1_400 5116 21687 1953 650 2899 −302 Pseudomonas P31961 (ec:4.2.1.12) (de:dehydratase)) aeruginosa 12166305_c1_402 5117 21688 507 168 109 −5 Aspergillus Contig3847 GTC ORF with score 222 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 4494581_c1_403 5118 21689 831 276 1220 −124 Pseudomonas U50932 (sr:pseudomonas aeruginosa strain=pao1) aeruginosa (de:pseudomonas aeruginosa glucose uptake regulatory protein (gltr)gene, complete cds.) (nt:glucose uptake regulatory gene; two- component) 36148561_c1_407 5119 21690 1422 473 3260040_c1_409 5120 21691 909 302 485 −46 Pyrococcus AP000005 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 994001-1166000 nt. position(5/7).) (nt:similar to pir:s75972 percent ident: 35.610 in) 14179032_c1_412 5121 21692 882 294 1571 −161 Pseudomonas S42207 aeruginosa 13102281_c2_413 5122 21693 474 157 145 −10 Bacillus E69867 subtilis/ Bacillus globigii 33847306_c2_414 5123 21694 366 121 93 −5 Enterococcus CONTIG368 GTC ORF with score 191 to: (ai:115800) faecium C (or:Bacillus subtilis) 22347681_c2_415 5124 21695 705 234 24850716_c2_420 5125 21696 2247 748 97 −1 Bartonella AF014832 (de:bartonella doshiae 60 kda heat shock doshiae protein (groel) gene, partialcds.) 20097686_c2_421 5126 21697 984 327 649 −63 Arabidopsis AL022603 (sr:thale cress) (de:arabidopsis thaliana dna thaliana chromosome 4, bac clone f18e5 (essaiiproject).) (nt:similarity to pig3 homo sapiens, pat:g2754812..) 32282006_c2_423 5127 21698 1308 435 330 −30 Enterobacter CONTIG434 GTC ORF with score 343 to: (ai:7501766899) cloacae (or:Klebsiella pneumoniae) 36072917_c2_425 5128 21699 1050 349 202 −16 Klebsiella Contig057A GTC ORF with score 202 to: (ai:7000774027) pneumoniae (or:Pseudomonas aeruginosa) 29425890_c2_439 5129 21700 801 266 557 −54 Escherichia P24187 (ec:2.3.—) (de:protein b)) coli 8508_c2_441 5130 21701 1239 412 126 −4 Rattus Q99372 (sr:,rat) (de:clastin precursor (tropoelastin) norvegicus (fragment)) 10745907_c2_448 5131 21702 1188 395 132 −8 Klebsiella Contig499A GTC ORF with score 132 to: (ai:7000774050) pneumoniae (or:Pseudomonas aeruginosa) 25494033_c2_450 5132 21703 1803 600 646 −63 Aquifex F70480 aeolicus 31777130_c2_453 5133 21704 1389 462 731 −72 Arabidopis AC003040 (sr:thale cress) (de:arabidopsis thaliana thaliana chromosome ii bac f26b6 genomic sequence,complete sequence.) (nt:hypothetical protein) 9847090_c2_457 5134 21705 762 253 208 −17 Escherichia U82664 (de:escherichia coli minutes 9 to 11 genomic coli sequence.) (nt:hypothetical protein) 31847900_c2_463 5135 21706 1047 348 155 −8 Plasmodium U08977 (de:plasmodium vivax isolate ch-3 vivax circumsporozoite protein gene,partial cds.) 15708342_c2_464 5136 21707 339 112 101 −4 Canis S33121 (cl:homeotic protein cdp:cut repeat familiaris homology:homeobox homology) (sr:, dog) 12788293_c2_466 5137 21708 1041 346 16822056_c2_474 5138 21709 1530 509 14347525_c2_476 5139 21710 804 267 102 −2 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29942656_c2_480 5140 21711 669 222 405 −38 Escherichia P24250 (de:hypothetical 20.1 kd protein in seld-sppa coli intergenic region (orf183)) 36031683_c2_488 5141 21712 582 193 100 −3 Homo sapiens S16506 (sr:,man) 11892787_c2_489 5142 21713 756 251 115 −4 Plasmodium U08979 (de:plasmodium vivax isolate ch-5 vivax circumsporozoite protein gene,partial cds.) 26660750_c2_490 5143 21714 918 305 682 −67 Escherichia P45847 (de:hypothetical 24.5 kd protein in trpl-btur coli intergenic region) 32208531_c2_491 5144 21715 1020 339 207 −14 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 24847955_c2_505 5145 21716 378 125 96 −4 Dictyostelium Q04503 (sr:,slime mold) (de:prespore protein dp87 discoideum precursor) 30570905_c2_506 5146 21717 873 290 164 −10 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 123/162.) (nt:rv2839c, (mtcy16b7.03), len: 900.probable infb,) 24692302_c2_508 5147 21718 1323 440 937 −94 Brucella L35038 (de:brucella abortus cytoplasmic protein (p39) abortus gene, complete cds.) (nt:39kda protein; putative) 32308281_c2_510 5148 21719 801 266 306 −27 Klebsiella Contig471A GTC ORF with score 306 to: (ai:7000774112) pneumoniae (or:Pseudomonas aeruginosa) 31807256_c2_511 5149 21720 744 247 113 −6 Mycobacterium M15467 (sr:mycobacterium tuberculosis (strain tuberculosis erdman) dna) (de:m. tuberculosis 65 kda antigen (cell wall protein a) gene.) (nt:orf e145, putative) 7292086_c3_516 5150 21721 1398 465 107 −3 Enterobacter CONTIG261 GTC ORF with score 554 to: (ai:7501745490) cloacae (or:Klebsiella pneumoniae) 12949078_c3_526 5151 21722 498 165 152 −11 Klebsiella Contig060A GTC ORF with score 167 to: (ai:7000767067) pneumoniae (or:Pseudomonas aeruginosa) 13802191_c3_534 5152 21723 1326 441 258 −22 Bacillus F69768 subtilis/ Bacillus globigii 36426078_c3_535 5153 21724 2259 752 6304130_c3_536 5154 21725 903 300 406 −38 Klebsiella Contig452A GTC ORF with score 558 to: (ai:7000814235) pneumoniae (or:Enterobacter cloacae) 13131905_c3_540 5155 21726 381 126 97 −4 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31753806_c3_541 5156 21727 1419 472 97 −2 Acinetobacter CONTIG198 GTC ORF with score 402 to: (ai:7000692616) baumannii C (or:Bacillus subtilis) (de:bacillus subtilis genomic dna 23.9kb fragment.) 14664063_c3_543 5157 21728 1212 403 3151933_c3_545 5158 21729 1155 384 440 −41 Lyme disease H70117 (sr:, lyme disease spirochete) spirochete 16101410_c3_547 5159 21730 1935 644 2217 −230 Escherichia P32705 (de:hypothetical 59.2 kd protein in soxr-acs coli intergenic region (f549)) 32532133_c3_548 5160 21731 423 140 94 −3 Schizo- Z95620 (sr:fission yeast) (de:s. pombe chromosome ii saccharomyces cosmid c3d6.) (nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 34064692_c3_550 5161 21732 1059 352 134 −6 Pseudomonas X80272 (de:p. putida pprb gene.) putida 26073816_c3_555 5162 21733 2295 764 250 −19 Klebsiella Contig516A GTC ORF with score 124 to: pneumoniae (de:mycobacterium smegmatis iron uptake genes, fxba (fxba) gene,partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxtc (fxte), and fxtf (fxtf)genes, complete cds.) (nt:similar to . . . 5988581_c3_559 5163 21734 726 241 143 −10 Enterobacter CONTIG341 GTC ORF with score 366 to: (ai:7501746814) cloacae (or:Klebsiella pneumoniae) 11461_c3_561 5164 21735 726 241 435 −41 Escherichia G64892 coli 6337706_c3_568 5165 21736 714 237 160 −9 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 17032010_c3_573 5166 21737 1077 358 339 −31 Pseudomonas U73506 (de:pseudomonas aeruginosa ornithine aeruginosa utilization regulatory (orur)gene, complete cds.) (nt:regulatory locus for ornithine utilization) 33829542_c3_580 5167 21738 1467 488 16994842_c3_582 5168 21739 933 310 95 −1 Chlamy- U73817 (de:chlamydomonas reinhardtii lrg5 mrna, domonas complete cds.) reinhardtii strain UTEX 1061 36111693_c3_586 5169 21740 774 257 184 −14 Klebsiella Contig499A GTC ORF with score 150 to: (ai: 161948) pneumoniae (or:Rhizobium sp.) (sr:rhizobium sp (strain ic 3342) (clone: pmnu4) (clone library: cosmi) (de:rhizobium sp. lcrabcde genes, complete cds's. 4724162_c3_588 5170 21741 1080 359 502 −48 Haemophilus P44176 (de:hypothetical protein hi1400) influenzae 7276030_c3_590 5171 21742 972 323 395 −37 Bacillus P35154 (de:hypothetical 29.6 kd protein in ribt-dacb subtilis/ intergenic region (orfx7)) Bacillus globigii 12351008_c3_591 5172 21743 978 325 173 −10 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 32555441_c3_592 5173 21744 690 229 11815680_c3_593 5174 21745 270 89 6729168_c3_594 5175 21746 1107 368 271 −24 Aspergillus Contig9906 GTC ORF with score 286 to: (ai:7591763937) fumigatus (or:Klebsiella pneumoniae) 10333541_c3_595 5176 21747 2880 959 531 −50 Helicobacter G64657 pylori 31501458_c3_597 5177 21748 1581 526 378 −35 Coxiella I40646 (cl:sensor histidine kinase homology) burnetii 17058457_c3_598 5178 21749 387 128 162 −12 Escherichia P45736 (de:hypothetical 14.0 kd protein in fabi-sapf coli intergenic region) 9844681_c3_599 5179 21750 1116 371 532 −51 Pyrococcus AP000005 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 994001-1166000 nt. position(5/7).) (nt:similar to :spu435263 percent ident: 30.627) 25487916_c3_600 5180 21751 2031 676 871 −87 Rhizobium sp. P55604 (sr:ngr234,) (de:probable abc transporter atp- binding protein y4os) 17004155_f1_1 5181 21752 1794 597 29926040_f1_3 5182 21753 1629 542 126 −5 African clawed S31719 (sr:, african clawed frog) frog 34413513_f1_5 5183 21754 921 306 116 −5 Escherichia P37665 (de:precursor (o219)) coli 32536536_f1_19 5184 21755 543 180 11831656_f1_22 5185 21756 768 255 197 −16 Klebsiella Contig543A GTC ORF with score 197 to: (ai:7000774226) pneumoniae (or:Pseudomonas aeruginosa) 21891083_f1_26 5186 21757 1026 341 480 −46 Rhizobium X89816 (de:r. legominosarum dna for gsta and gstr leguminosarum genes.) 30741281_f1_28 5187 21758 765 254 123 −4 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 12542193_f1_30 5188 21759 714 237 12680340_f1_42 5189 21760 1176 391 103 −2 Plasmodium P04922 (sr:nuri,) (de:circumsporozoite protein knowlesi precursor (cs)) 29863156_f1_43 5190 21761 231 76 16112515_f1_47 5191 21762 1554 517 334 −30 Methano- C69060 bacterium thermo- autotrophicum 7235383_f1_55 5192 21763 5103 1700 236 −15 Chinese oak AF083334 (sr:chinese oak silkmoth) (de:antheraea pernyi silkmoth fibroin gene, complete cds.) 22110432_f1_58 5193 21764 249 82 91 −4 Daucus carota U47097 (sr:carrot strain=danver half-long) (de:daucus var. sativus carota glycine-rich protein mrna, somatic embryo clonegea44, partial cds.) 10286541_f1_68 5194 21765 675 224 177 −13 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region 4400127_f1_69 5195 21766 1242 413 2093 −216 Pseudomonas P07345 (ec:4.2.1.20) (de:tryptophan synthase beta aeruginosa chain,) 24848957_f1_74 5196 21767 234 77 114 −6 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region 22838455_f1_75 5197 21768 1173 390 878 −88 Rhizobium U39940 (fn:converts choline-o-sulfate to choline) meliloti (ec:3.1.6.6) (de:sinorhizobium meliloti bet (megaplasmid operon, complete sequence.) (nt:betc) pRME41B SYM) 16926030_f1_76 5198 21769 1284 427 253 −21 Lyme disease H70117 (sr:, lyme disease spirochete) spirochete 26610791_f1_77 5199 21770 1911 636 113 −3 equine herpes- D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) virus type 1 (de:equine herpesvirus 1 dna for tegument EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 12977257_f1_78 5200 21771 519 172 100 −3 Gallus gallus P09987 (sr:,chicken) (de:histone h1) domesticus 32676881_f1_80 5201 21772 549 182 156 −10 Streptomyces AL022374 (de:streptomyces coelicolor cosmid 5b8.) coelicolor (nt:sc5b8.08, probable abc transporter, len: 744 aa;) 33477268_f1_84 5202 21773 498 165 163 −11 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 16927205_f1_86 5203 21774 624 207 191 −15 Enterobacter CONTIG372 GTC ORF with score 191 to: (ai:7000774290) cloacae (or:Pseudomonas aeruginosa) 13003458_f1_87 5204 21775 1227 408 21486417_f1_89 5205 21776 579 192 485 −46 Escherichia S23107 (cl:polypeptide deformylase) (ec:3.5.1.27) coli 12204531_f1_90 5206 21777 999 332 1580 −162 Pseudomonas AF073952 (de:pseudomonas aeruginosa methionyl-trna aeruginosa formyltransferase (fmt) gene,complete cds.) 25492205_f1_92 5207 21778 1401 466 1538 −158 Vibrio P39448 (de:trk system potassium uptake protein trka) alginolyticus 2628168_f1_93 5208 21779 588 195 97 −3 Klebsiella Contig546A GTC ORF with score 127 to: (ai:7000780553) pneumoniae (or:Pseudomonas aeruginosa) 24713208_f2_99 5209 21780 2067 688 160 −8 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 9942813_f2_100 5210 21781 1167 388 131 −5 Alphaherpes- S04713 (cl:herpesvirus immediate-early protein ie175) virus pseudorabies virus PRV 25440641_f2_101 5211 21782 501 166 110 −6 Homo sapiens S72602 (sr:human 697 pre-b cell acute lymphocytic leukemia cell line) (de:bc12 (human, 697 pre-b cell acute lymphocytic leukemia cell line,genomic, 454 nt).) 16928956_f2_102 5212 21783 615 204 196 −13 equine herpes- AF030027 (fn:very large tegument protein) (de:equine virus type 4 herpesvirus 4 strain ns80567, complete EHV-4 genome.) (nt:counterpart of hsv-1 gene ul36 and vzv gene 22) 13145406_f2_103 5213 21784 513 170 96 −3 Pseudomonas X80272 (de:p. putida pprb gene.) putida 12614392_f2_107 5214 21785 453 150 106 −6 longfin squid S56117 (sr:, longfin squid) 10642628_f2_110 5215 21786 801 266 590 −57 Escherichia P45770 (de:hypothetical 28.4 kd protein in rrnd-aroe coli intergenic region (o256)) 15754541_f2_111 5216 21787 1674 557 16532331_f2_113 5217 21788 528 175 110 −7 Klebsiella Contig559A GTC ORF with score 352 to: (ai:7000838944) pneumoniae (or:Enterobacter cloacae) 478218_f2_117 5218 21789 900 299 183 −11 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, sapiens clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 10627018_f2_118 5219 21790 1011 336 245 −21 Klebsiella Contig543A GTC ORF with score 245 to: (ai:7000774322) pneumoniae (or:Pseudomonas aeruginosa) 26694155_f2_119 5220 21791 1341 446 542 −52 Escherichia P39380 (de:hypothetical 24.6 kd protein in iada-mcrd coli intergenic region (o218)) 12995658_f2_122 5221 21792 264 87 15080127_f2_127 5222 21793 567 188 114 −5 mice|C57BL/ D29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 2079581_f2_129 5223 21794 1299 432 124 −4 Streptomyces AL031231 (de:streptomyces coelicolor cosmid 3c3.) coelicolor (nt:sc3c3.03c, unknown, : 1083 aa; contains three) 1383501_f2_131 5224 21795 399 132 107 −6 Plasmid RK2 A49852 31726386_f2_136 5225 21796 525 174 123 −6 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 4089067_f2_142 5226 21797 231 76 12603967_f2_155 5227 21798 4953 1650 228 −14 Chinese oak AF083334 (sr:chinese oak silkmoth) (de:antheraea pernyi silkmoth fibroin gene, complete cds.) 1463582_f2_163 5228 21799 306 101 113 −6 white AF020261 (sr:white sandalwood) (de:santalum album sandalwood proline rich protein mrna, complete cds.) 35254163_f2_165 5229 21800 687 228 93 −3 Klebsiella Contig217A GTC ORF with score 221 to: (ai:405746) pneumoniae (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence (mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 9947806_f2_166 5230 21801 648 215 793 −79 Pseudomonas P24908 (de:putative transcriptional regulator aeruginosa (fragment)) 15800693_f2_167 5231 21802 981 326 103 −3 Orf virus B34768 26666433_f2_168 5232 21803 483 160 101 −5 Indian corn Q01900 (sr:,maize) (de:mfs14 protein precursor) 31455066_f2_171 5233 21804 417 138 125 −7 mice|C57BL/ E29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 14972931_f2_173 5234 21805 1608 535 519 −50 Aquifex G70409 aeolicus 5861656_f2_178 5235 21806 1968 655 458 −43 Pseudomonas S59507 putida 32557293_f2_181 5236 21807 411 136 108 −6 Clostridium Contig184H GTC ORF with score 108 to: (ai:7000774385) acetobutylicum (or:Pseudomonas aeruginosa) 24066656_f2_186 5237 21808 1152 383 161 −8 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 36539200_f2_189 5238 21809 333 110 110 −6 Aquifex F70422 (cl:tetratricopeptide repeat homology) aeolicus 29977041_f3_192 5239 21810 1344 447 116 −4 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 12676631_f3_193 5240 21811 1164 387 347 −31 Escherichia P75831 (de:hypothetical abc transporter atp-binding coli protein ybjz) 13022650_f3_195 5241 21812 699 232 138 −7 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10395841_f3_196 5242 21813 1806 601 32052266_f3_198 5243 21814 543 180 150 −9 Canadian hard S02262 (cl:glutenin) (sr:, common wheat) winter wheat 4426537_f3_199 5244 21815 1236 411 10447705_f3_200 5245 21816 684 227 395 −37 Klebsiella Contig378A GTC ORF with score 1490 to: pneumoniae (ai :7000829983) (or:Enterobacter cloacae) 15652041_f3_201 5246 21817 1389 462 428 −40 Klebsiella Contig378A GTC ORF with score 1490 to: pneumoniae (ai :7000829983) (or:Enterobacter cloacae) 15116292_f3_202 5247 21818 699 232 216 −19 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 99/162.) (nt:rv2233, (mtcy427.14), unknown, len: 135. similar) 29822530_f3_203 5248 21819 1341 446 35628957_f3_205 5249 21820 459 152 29323305_f3_209 5250 21821 777 258 122 −5 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 32313507_f3_211 5251 21822 561 186 344 −31 Aspergillus Contig5454 GTC ORF with score 344 to: (ai:7000774415) fumigatus (or:Pseudomonas aeruginosa) 26370951_f3_215 5252 21823 345 114 110 −5 Paramecium U42580 (de:paramecium bursaria chlorella virus 1, bursaria complete genome.) (nt:contains pro-rich px Chlorella motifs: spkpp (20x), peppa) virus 1 11817661_f3_221 5253 21824 1806 601 5097016_f3_229 5254 21825 1815 604 156 −7 African clawed M63596 (sr:xenopus laevis neurola cdna to mrna) frog (de:xenopus laevis alpha-1 collagen type ii′ mrna, complete cds.) 35255156_f3_238 5255 21826 495 164 115 −5 Caenorhabditis Z77662 (de:caenorhabditis elegans cosmid f47b8, elegans complete sequence.) (nt:predicted using genefinder) 31896030_f3_242 5256 21827 3282 1093 299 −22 Homo sapiens AC004493 (sr:human) (de:homo sapiens chromosome 16, cosmid clone 373c8 (lanl), completesequence.) 3382951_f3_247 5257 21828 1275 424 14862503_f3_250 5258 21829 2103 700 1345 −137 Pseudomonas P07344 (cc:4.2.1.20) (de:tryptophan synthase alpha aeruginosa chain,) 11932880_f3_252 5259 21830 378 125 92 −3 Erwinia Y13670 (fn:involved in regulation of virulence factors) carotovora (de:erwinia carotovora exps gene.) subsp. carotovora 13089433_f3_254 5260 21831 2592 863 286 −22 Rhizobium U39940 (fn:converts choline-o-sulfate to choline) meliloti (cc:3.1.6.6) (de:sinorhizobium meliloti bet (megaplasmid operon, complete sequence.) (nt:betc) pRME41B SYM) 22945808_f3_255 5261 21832 642 213 119 −5 Streptomyces L20249 (sr:streptomyces coriofaciens (library isp coriofaciens 5485) dna) (de:streptomyces coriofaciens beta- ketoacyl synthase homologue gene,partial cds.) (nt:homologous to saccharopolyspora erythraea) 33705033_f3_261 5262 21833 759 252 143 −8 Caenorhabditis Z70756 (de:caenorhabditis elegans cosmid t06c4, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 20806416_f3_263 5263 21834 1341 446 34645941_f3_267 5264 21835 996 331 1655 −170 Pseudomonas P43903 (ec:1.6.5.5) (de:quinone oxidoreductase, aeruginosa (nadph:quinone reductase)) 31914590_f3_271 5265 21836 462 153 109 −4 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 major immediate-earlygenes.) (nt:similar to HHV-6 hhv6a u86, region ie-b) 12398915_f3_274 5266 21837 2046 681 1023 −103 Escherichia P36929 (de:sun protein (fmu protein)) coli 22086441_f3_276 5267 21838 1302 433 15738458_f3_278 5268 21839 363 120 36526577_f3_279 5269 21840 222 73 2476658_c1_286 5270 21841 1458 485 521 −50 Enterobacter CONTIG372 GTC ORF with score 521 to (ai:7000774490) cloacae (or:Pseudomonas aeruginosa) 15704207_c1_289 5271 21842 1710 569 163 −11 Enterobacter CONTIG372 GTC ORF with score 163 to: (ai:7000774493) cloacae (or:Pseudomonas aeruginosa) 15753812_c1_290 5272 21843 1131 376 115 −4 Bacillus P45932 (de:hypothetical 25.3 kd protein in spoiiic- subtilis/ cwla intergenic region) Bacillus globigii 14964765_c1_291 5273 21844 837 278 526 −50 Escherichia P30852 (de:smf protein) coli 13782031_c1_296 5274 21845 402 133 158 −10 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin attachment cerevisiae subunit precursor) 30707068_c1_301 5275 21846 585 194 16901006_c1_302 5276 21847 471 156 114 −7 longfin squid S56117 (sr:,longfin squid) 34635417_c1_304 5277 21848 669 222 139 −7 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 major immediate-earlygenes.) (nt:similar to HHV-6 hhv6a u86, region ie-b) 31348843_c1_308 5278 21849 1227 408 392 −37 Aspergillus Contig7087 GTC ORF with score 392 to (ai:7000774512) fumigatus (or:Pseudomonas aeruginosa) 36569782_c1_309 5279 21850 552 183 139 −9 Achromobacter A61183 georgio- politanum 34246008_c1_315 5280 21851 1302 433 370 −34 Enterobacter CONTIG492 GTC ORF with score 573 to: (ai:7501798310) cloacae (or:Klebsiella pneumoniae) 32681416_c1_317 5281 21852 723 240 165 −10 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 10439512_c1_320 5282 21853 1770 589 158 −8 Burkholderia U41162 (sr:burkholderia cepacia strain=17616) cepacia (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 14925707_c1_325 5283 21854 6876 2291 402 −32 Neisseria AF030941 (de:neisseria meningitidis putative secreted meningitidis protein (pspa) gene,complete cds.) (nt:amino- terminus similar to a number of secreted) 24400450_c1_327 5284 21855 183 60 24504035_c1_330 5285 21856 522 173 36042253_c1_333 5286 21857 900 299 118 −3 mice|C57BL/ Q60847 (sr:,mouse) (de:collagen alpha 1(xii) chain 6xCBA/ precursor) CaJ hybrid 36226402_c1_337 5287 21858 438 146 12944160_c1_338 5288 21859 450 149 3251653_cl_360 5289 21860 504 167 100 −2 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 16892507_c1_365 5290 21861 513 170 449 −42 Escherichia P23929 (de:osmotically inducible protein c) coli 15723956_c1_376 5291 21862 1629 542 120 −4 Homo sapiens AF000561 (sr:human) (de:homo sapiens ttf-i interacting peptide 21 mrna, partial cds.) (nt:tip21; transcription termination factor i) 16143956_c1_377 5292 21863 1179 392 110 −3 Rattus P47709 (sr:,rat) (de:rabphilin-3a) norvegicus 10802316_c1_379 5293 21864 945 314 106 −4 Nephila AF027737 (de:nephila clavipes minor ampullate silk clavipes protein misp2 mrna, partialcds.) 16972955_c1_386 5294 21865 2547 849 143 −6 Pseudomonas A36128 aeruginosa 33958121_c2_388 5295 21866 288 95 22894708_c2_392 5296 21867 942 313 99 −4 Enterobacter CONTIG372 GTC ORF with score 99 to: (ai:7000774596) cloacae (or:Pseudomonas aeruginosa) 5176916_c2_403 5297 21868 690 229 417 −39 Escherichia P45748 (de:hypothetical 20.8 kd protein in aroe-smg coli intergenic region) 9895803_c2_404 5298 21869 1386 461 301 −27 Klebsiella Contig368A GTC ORF with score 301 to: (ai:7000774608) pneumoniae (or:Pseudomonas aeruginosa) 35272916_c2_407 5299 21870 780 259 146 −8 Aspergillus Contig9870 GTC ORF with score 111 to: (ai:195953) fumigatus (or:Homo sapiens) (sr:, man) 24397563_c2_408 5300 21871 1041 346 36427080_c2_409 5301 21872 747 248 154 −8 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 30730282_c2_411 5302 21873 846 281 155 −8 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 12632307_c2_414 5303 21874 483 160 101 −3 Dissostichus U58944 (de:dissostichus mawsoni afgp antifreeze mawsoni glycopeptide polyproteinprecursor gene, complete cds.) (nt:afgp=antifreeze glycopeptide, cleavage of) 4317063_c2_416 5304 21875 909 302 393 −36 Escherichia P32064 (de:glycine cleavage system transcriptional coli activator) 21578127_c2_420 5305 21876 1167 388 251 −21 Klebsiella Contig559A GTC ORF with score 279 to: (ai:7000838892) pneumoniae (or:Enterobacter cloacae) 16902205_c2_421 5306 21877 360 119 271 −24 Enterobacter CONTIG492 GTC ORF with score 458 to: (ai:7501798412) cloacae (or:Klebsiella pneumoniae) 31894530_c2_422 5307 21878 954 317 1477 −151 Pseudomonas S12643 aeruginosa 32671878_c2_425 5308 21879 1830 609 784 −78 Erwinia L39897 (de:erwinia chrysanthemi phospholipase c chrysanthemi (plca) gene, partial cds; hrpf(hrpf), hrpg (hrpg), hrcc (hrcc), hrpt (hrpt), hrpv (hrpv), hrpnharpin (hrpn), orf1, and hecb (hecb) genes, complete cds; and heca(heca) gene, partial cds.) (nt:simil . . . 22548191_c2_426 5309 21880 1551 516 269 −20 Canadian hard B30843 (cl:glutenin) (sr:, common wheat) winter wheat 15726467_c2_428 5310 21881 2163 720 299 −23 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 12589416_c2_432 5311 21882 411 136 140 −9 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34589592_c2_438 5312 21883 345 114 14103450_c2_440 5313 21884 285 94 292 −26 Escherichia P46857 (de:hypothetical 10.6 kd protein in gntr-ggt coli intergenic region (o94)) 15752125_c2_441 5314 21885 432 143 32714208_c2_446 5315 21886 1431 476 2266 −235 Pseudomonas JC6026 (cc:2.4.2.—) aeruginosa 31666462_c2_449 5316 21887 729 242 24488405_c2_450 5317 21888 384 127 32618967_c2_453 5318 21889 1929 642 146 −7 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 148/162.) (nt:rv3508, (mtv023.15), 1en: 1901. member of) 32286467_c2_459 5319 21890 687 228 209 −16 Bacillus F69837 subtilis/ Bacillus globigii 32548893_c2_461 5320 21891 585 194 179 −14 Enterococcus CONTIG625 GTC ORF with score 282 to: (ai:7000740108) faecalis (or:Enterococcus faecium) 7288532_c2_462 5321 21892 495 164 94 −2 equine S55618 (or:Enterococcus faecium) herpesvirus type 2 EHV-2 29922818_c2_463 5322 21893 606 201 139 −10 Aspergillus Contig5454 GTC ORF with score 139 to: (ai:7000774667) fumigatus (or:Pseudomonas aeruginosa) 25822081_c2_467 5323 21894 750 249 6447706_c2_468 5324 21895 639 212 96 −3 Aspergillus Contig7067 GTC ORF with score 217 to: (ai:194919) fumigatus (or:Homo sapiens) (sr:, man) (mp:11p15.5- 11p15.5) 11197291_c2_470 5325 21896 1380 459 36019375_c2_474 5326 21897 2118 705 2089 −216 Escherichia P27298 (ec:3.4.24.70) (de:oligopeptidase a,) coli 12383442_c2_476 5327 21898 1209 402 805 −80 Brucella AF059568 (de:brucella melitensis hypothetical protein melitensis gene, partial cds.) (nt:transmembrane protein) 16032642_c2_479 5328 21899 1209 402 12994555_c2_481 5329 21900 909 302 112 −4 Klebsiella Contig520A GTC ORF with score 466 to: (ai:7000822272) pneumoniae (or:Enterobacter cloacae) 13002167_c3_490 5330 21901 507 168 102 −5 Aspergillus Contig8431 GTC ORF with score 199 to: (ai:7500745749) fumigatus (or:Candida albicans) 2554816_c3_496 5331 21902 501 166 91 −2 Klebsiella Contig490A GTC ORF with score 124 to: (ai:4000725427) pneumoniae (or:Mus spretus) (sr:western wild mouse) (de:mus spretus sex determining protein (sry) gene, complete cds.) (nt:hmg box transcription factor) 24647903_c3_498 5332 21903 1140 379 124 −5 Haemophilus P43862 (de:dna processing chain a) influenzae 34072716_c3_501 5333 21904 1020 339 1686 −173 Pseudomonas P43898 (cc:1.3.3.3) (de:(coproporphyrinogenase) aeruginosa (coprogen oxidase)) 33847906_c3_502 5334 21905 882 293 1399 −143 Pseudomonas P43904 (cc:1.1.1.25) (de:shikimate 5-dehydrogenase,) aeruginosa 15119792_c3_504 5335 21906 441 146 146 −10 Drosophila P13728 (sr:,fruit fly) (de:salivary glue protein sgs-3 yakuba precursor) 13027181_c3_505 5336 21907 1167 388 10836456_c3_506 5337 21908 741 246 121 −5 Aspergillus Contig9386 GTC ORF with score 627 to: (ai:98607) fumigatus (or:Clostridium thermocellum) (de:c. thermocellum anca gene.) (nt:porf1) 22085166_c3_509 5338 21909 624 207 112 −3 no gb U52064 (de:kaposi's sarcoma-associated herpes-like taxonomy virus orf73 homolog gene,complete cds.) match (nt:herpesvirus saimiri orf73 homolog) 35808408_c3_510 5339 21910 414 137 100 −5 Sarcocystis S44152 muris 11819557_c3_514 5340 21911 306 101 101 −6 Aspergillus Contig7087 GTC ORF with score 101 to: (ai:7000774718) fumigatus (or:Pseudomonas aeruginosa) 10008557_c3_515 5341 21912 471 156 96 −3 Schizophyllum AF005405 (fn:oxidation of the 5′-hydroxymethyl of) commune (de:schizophyllum commune b2-aldehyde- forming enzyme mrna, completecds.) (nt:secreted enzyme) 13152155_c3_517 5342 21913 603 200 154 −11 fly agaric Y12886 (fn:betalain and muscaflavin biosynthesis) (sr:fly agaric) (de:amanita muscaria doda gene.) 15912876_c3_519 5343 21914 561 186 119 −8 Klebsiella Contig402A GTC ORF with score 119 to: (ai:7000774723) pneumoniae (or:Pseudomonas aeruginosa) 11896005_c3_523 5344 21915 474 157 138 −10 Klebsiella Contig559A GTC ORF with score 352 to: (ai:7000838944) pneumoniae (or:Enterobacter cloacae) 5178787_c3_525 5345 21916 744 247 96 −4 Aspergillus Contig8078 GTC ORF with score 219 to: (ai:175260) fumigatus (or:Volvox carteri) 24616390_c3_526 5346 21917 279 92 35254590_c3_527 5347 21918 411 136 235 −20 Pseudomonas M21093 (sr:pseudomonas aeruginosa(strain pac174) aeruginosa (clone: pzaz 167.) dna) (de:p. aeruginosa activator of trpba (trpi) gene, complete cds.) (nt:orf; putative) 20052188_c3_533 5348 21919 4158 1385 727 −67 Bordetella M60351 (sr:b. pertussis (strain bp338) dna) pertussis (de:b. pertussis filamentous hemagglutinin (fhab) gene, complete cds.) 13148961_c3_535 5349 21920 2469 822 348 −28 Micrococcus JQ0405 luteus 21589141_c3_537 5350 21921 1152 383 147 −8 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence (mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 24644638_c3_541 5351 21922 477 158 32283330_c3_544 5352 21923 534 177 105 −3 Rattus U49056 (sr:norway rat) (de:rattus norvegicus ctd- norvegicus binding sr-like protein ral mrna, completecds.) (nt:ctd-binding sr-like protein) 6354057_c3_552 5353 21924 876 291 91 −1 Orf virus B34768 11753775_c3_557 5354 21925 195 64 12111592_c3_559 5355 21926 1446 481 900 −90 Bacillus Z93940 (de:b. subtilis genomic dna fragment from yuca subtilis/ to yuch.) (nt:putative) Bacillus globigii 12159427_c3_563 5356 21927 228 75 26832902_c3_567 5357 21928 297 98 121 −7 Caenorhabditis P17656 (de:cuticle collagen 2) elegans 13083511_c3_570 5358 21929 927 308 694 −69 Klebsiella Contig543A GTC ORF with score 1088 to: pneumoniae (ai :7000830231) (or: Enterobacter cloacae) 24644216_c3_573 5359 21930 240 79 120 −7 Pseudomonas M21093 (sr:pseudomonas aeruginosa (strain pac174) aeruginosa (clone: pzaz 167.) dna) (de:p. aeruginosa activator of trpba (trpi) gene, complete cds.) (nt:orf; putative) 24739658_c3_578 5360 21931 564 187 113 −5 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus glutamine 6xCBA/ repeat protein-1 mrna, complete cds.) (nt:grp- CaJ hybrid 1) 10652042_c3_581 5361 21932 507 168 116 −5 Homo sapiens M74027 (sr:homo sapiens (tissue library: lambda-gem- 11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 10823465_c3_582 5362 21933 531 176 164 −11 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31894165_c3_583 5363 21934 657 218 91 −3 Enterobacter CONTIG451 GTC ORF with score 634 to: (ai:7501738854) cloacae (or:Klebsiella pneumoniae) 35784530_c3_587 5364 21935 1620 539 127 −5 Plasmodium A26255 (cl:circumsporozoite protein:thrombospondin cynomolgi type repeat homology) 36033131_c3_591 5365 21936 429 142 110 −6 Caenorhabditis U55373 (de:caenorhabditis elegans cosmid f26f12.) elegans (nt:similar to cuticular collagen; coded for by c.) 33730280_f1_1 5366 21937 735 244 239 −20 Bacillus S32217 megaterium 14570468_f1_4 5367 21938 573 190 135 −7 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) herpesvirus type 1 EVH-1 16277180_f1_7 5368 21939 831 276 220 −17 Boreogadus U4320O (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16910431_f1_10 5369 21940 489 162 247 −21 Acinetobacter CONTIG188 GTC ORF with score 247 to: (ai:7000774806) baumannii C (or:Pseudomonas aeruginosa) 16300907_f1_12 5370 21941 975 324 146 −10 Enterobacter CONTIG504 GTC ORF with score 331 to: (ai:7501758768) cloacae (or:Klebsiella pneumoniae) 16929068_f2_16 5371 21942 720 239 123 −5 Dictyostelium P36417 (sr:,slime mold) (de:g-box binding factor discoideum (gbf)) 16303966_f2_18 5372 21943 1461 486 149 −7 Arabidopsis AF019380 (sr:thale cress) (de:arabidopsis thaliana thaliana putative phosphatidylinositol-4-phosphate5- kinase mrna, complete cds.) 14944782_f2_19 5373 21944 897 298 482 −46 Escherichia P45469 (de:hypothetical 24.8 kd protein in agai-mtr coli intergenic region (f226)) 35785836_f3_26 5374 21945 819 272 146 −8 Enterobacter CONTIG501 GTC ORF with score 481 to: (ai:7501763574) cloacae (or:Klebsiella pneumoniae) 22127281_f3_28 5375 21946 522 173 357 −34 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 8/162.) (nt:rv0130, (mtci5.04), len: 151, unknown, most) 33692658_f3_29 5376 21947 885 294 334 −30 Cyano- S74454 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 26656665_f3_34 5377 21948 879 293 264 −23 Enterobacter CONTIG486 GTC ORF with score 750 to: (ai:7501775728) cloacae (or:Klebsiella pneumoniae) 3257699_c1_35 5378 21949 1491 496 460 −43 Bacillus U61168 (de:bacillus firmus spore germination proteins firmus c2 (gerc2) and c3(gerc3) genes, partial cds, and 4-hydroxybenzoateoctaprenyltransferase (ubia) and 3-octaprenyl-4- hydroxybenzoatecarboxy-lyase (ubix) genes, complete cds.) 3223582_c1_42 5379 21950 636 211 124 −5 Klebsiella Contig519A GTC ORF with score 1047 to: pneumoniae (ai:7000790354) (or:Pseudomonas aeruginosa) 14260266_c1_44 5380 21951 891 296 131 −5 Plasmodium AF043636 (de:plasmodium chabaudi circumsporozoite chabaudi protein (cs) gene, partialcds.) 10417164_c2_46 5381 21952 852 283 778 77 Escherichia P37773 (ec:6.3.2.—) (de:ligase,) 32676905_c2_47 5382 21953 426 141 10802292_c2_51 5383 21954 990 329 134 −7 Chlamy- S19114 domonas reinhardtii strain UTEX 1061 2478840_c2_53 5384 21955 1098 365 417 −39 Escherichia P33373 (de:hypothetical 24.5 kd protein in pbpg-cdd coli intergenic region) 34473816_c2_54 5385 21956 639 212 97 −2 Enterobacter CONTIG502 GTC ORF with score 1181 to: cloacae (ai:7501793467) (or:Klebsiella pneumoniae) 13016083_c3_59 5386 21957 1200 399 142 −9 Enterobacter CONTIG433 GTC ORF with score 142 to: (ai:7000774855) cloacae (or:Pseudomonas aeruginosa) 6527208_c3_62 5387 21958 426 141 140 −10 Escherichia P33372 (de:hypothetical 14.6 kd protein in pbpg-cdd coli intergenic region) 12901916_c3_63 5388 21959 627 208 10647681_c3_64 5389 21960 393 131 108 −6 Hordeum X68600 (sr:barley) (de:h. vulgare pze40 gene.) vulgare 21961441_f1_1 5390 21961 399 132 117 −7 mice|C57BL/ Q06666 (sr:,mouse) (de:octapeptide-repeat protein t2) 6xCAB/ CaJ hybrid 32048566_f1_5 5391 21962 1164 387 21615792_f1_8 5392 21963 1593 530 188 −14 Klebsiella Contig537A GTC ORF with score 188 to: (ai:7000774868) pneumoniae (or:Pseudomonas aeruginosa) 23572156_f1_14 5393 21964 327 108 17010331_f1_15 5394 21965 1593 530 267 −22 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt: fiur; transmembrane sensor component of) 17036656_f1_18 5395 21966 546 181 207 −15 Saccharomyces P47179 (sr:,baker's yeast) (de:precursor) cerevisiae 33689163_f2_25 5396 21967 522 173 154 −11 mice|C57BL/ Q06666 (sr:,mouse) (de:octapeptide-repeat protein t2) 6xCBA CaJ hybrid 15710027_f2_26 5397 21968 534 177 95 −5 Cyano- S75575 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 4431902_f2_27 5398 21969 987 328 258 −21 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35650666_f2_31 5399 21970 1347 448 893 −89 Escherichia E64818 coli 31661668_f2_32 5400 21971 1452 483 190 −14 Enterobacter CONTIG341 GTC ORF with score 318 to: (ai:7501726546) cloacae (or:Klebsiella pneumoniae 36141466_f2_37 5401 21972 969 322 111 −3 Streptomyecs D31792 (sr:streptomyces griseus (strain:b2682) dna) griseus (de:streptomyces griseus dna for serine/threonine protein kinases,complete cds.) 12281301_f2_38 5402 21973 1497 498 25447958_f3_45 5403 21974 1683 560 367 −33 Bacillus A70058 subtilis/ Bacillus globigii 32518768_f3_56 5404 21975 2403 800 2097 −217 Ralstonia X97499 (de:a. eutrophus aleb and cysm genes.) 15117965_f3_57 5405 21976 333 110 90 −4 Homo sapiens AB000676 (sr:homo sapiens cdna to mrna) (de:homo sapiens mrna for jab, partial cds.) 1379591_c1_61 5406 21977 660 219 125 −6 Plasmid pAH4 JC2322 25894657_c1_75 5407 21978 879 292 107 −5 Methylo- L26406 (de:methylobacterium extorquens mau gene bacterium cluster, methylaminedehydrogenase large and extorquens small subunits, and amicyanin,(maufbedacjglmn) genes, complete cds.) (nt:orf1) 33869458_c2_86 5408 21979 1179 392 106 −3 Aspergillus Contig9447 GTC ORF with score 458 to: (ai:175260) fumigatus (or:Volvox carteri) 6042716_c2_87 5409 21980 1464 487 190 −14 Enterobacter CONTIG475 GTC ORF with score 319 to: (ai:7501734057) cloacae (or:Klebsiella pneumoniae) 30333330_c2_96 5410 21981 501 166 147 −9 Pseudomonas 754213 (de:p. aeruginosa algy gene.) aeruginosa 29459683_c2_98 5411 21982 561 186 90 −2 Pseudomonas AF087482 (de:pseudomonas aeruginosa clcc and ohbh aeruginosa genes, lys-r type regulatoryprotein (clcr), chlorocatechol-1,2-dioxygenase (clca),chloromuconate cycloisomerase (clcb), dienelactone hydrolase(clcd), maleylacetate reductase (clce). transposas . . . 33727006_c2_99 5412 21983 429 142 242 −21 Staphylococcus CONTIG061 GTC ORF with score 242 to: (ai:7000774959) epidermidis C (or:Pseudomonas aeruginosa) 3208267_c2_103 5413 21984 987 328 196 −15 Streptomyces AL031317 (de:streptomyces coelicolor cosmid 6g4.) coelicolor (nt:sc6g4.34, unknown, : 118 aa; similar to a) 22754157_c2_104 5414 21985 450 149 198 −16 Escherichia P16681 (de:phnb protein) coli 12130325_c3_108 5415 21986 996 331 378 −35 Saccharomyces P38765 (sr:,baker's yeast) (de:hypothetical 32.6 kd cerevisiae protein in dap2-slt2 intergenic region) 14862531_c3_115 5416 21987 465 154 224 −18 Escherichia P37340 (de:hypothetical 49.4 kd protein in ribc-pykf coli intergenic region) 34480380_c3_116 5417 21988 1035 344 753 −74 Escherichia P37340 (de:hypothetical 49.4 kd protein in ribc-pykf coli intergenic region) 35839541_c3_117 5418 21989 825 274 134 −7 mice S50883 (sr:mice macrophage) (de:putative transcription regulator (clone t2, repetitive sequence)(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 31847961_c3_118 5419 21990 741 246 115 −4 Hordeum 518350 (cl:gliadin) (sr:, barley) vulgare 16880165_c3_119 5420 21991 723 240 119 −4 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) herpesvirus type 1 EVH-1 32556925_f1_3 5421 21992 909 302 379 −35 Pseudomonas P55176 (de:hypothetical 31.2 kd protein in pqqf fluorescens 5′region (orf2) 16265791_f1_8 5422 21993 2130 709 364 −33 Klebsiella Contig560A GTC ORF with score 364 to: (ai:7000774993) pneumoniae (or:Pseudomonas aeruginosa) 1384667_f1_10 5423 21994 285 94 94 −5 Enterobacter CONTIG475 GTC ORF with score 101 to: (ai:7000768449) cloacae (or:Pseudomonas aeruginosa) 2192816_f1_11 5424 21995 1518 505 149 −7 Epstein-Barr P03181 (sr:b95-8,human herpesvirus 4) virus (de:hypothetical bhlfl protein) 15727086_f1_12 5425 21996 1569 522 704 −69 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromatic- pnl1, complete plasmidsequence.) (nt:putative ivorans inner membrane protein similar to b.) 16495643_f1_14 5426 21997 1200 399 15755330_f1_18 5427 21998 1320 439 853 −85 Pseudomonas AF029714 (de:pseudomonas putida repressor (phan), putida regulatory protein (pham),enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad),phenylacetyl-coa ligase (phae). ring-oxidation . . . 25414058_f1_20 5428 21999 1269 422 491 −48 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 31/162.) (nt:rv0646c, (mtcy20h10.27c), len: 301 aa, similar to) 11025708_f1_41 5429 22000 1257 418 611 −59 Bacillus E69783 subtilis/ Bacillus globigii 14735941_f1_43 5430 22001 573 190 159 −10 Nephila AF027735 (de:nephila clavipes minor ampullate silk clavipes protein misp1 mrna, partialcds.) 960307_f1_44 5431 22002 1623 540 2574 −267 Pseudomonas B42902 (cl:aldehyde dehydrogenase (and+):aldehyde aeruginosa dehydrogenase homology) (cc:1.2.1.27) 35758587_f1_45 5432 22003 663 221 1018 −103 Pseudomonas P28811 (ec:1.1.1.31) (de:3-hydroxyisobutyrate aeruginosa dehydrogenase, (hibadh)) 16834808_f2_50 5433 22004 2493 830 644 −63 Pseudo- AF047839 (fn:0-6-methylguanine-dna methyltransferase) alteromonas (de:pseudoalteromonas sp. 59 putative glucosyl sp. S9 hydrolase precursor andadaptive response regulatory protein (ada) genes, complete cds.) 24089505_f2_55 5434 22005 1758 585 745 −75 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 157/162.) (nt:rv3797, (mtv026.02), len: 593. fade35, probable) 32697708_f2_58 5435 22006 2436 811 859 −86 Pseudomonas AF029714 (de:pseudomonas putida repressor (phan), putida regulatory protein (pham),enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad),phenylacetyl-coa ligase (phac), ring-oxidation 16495956_f2_62 5436 22007 366 121 119 −6 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) herpesvirus type 1 EVH-1 22781580_f2_71 5437 22008 1059 352 233 −20 Klebsiella Contig533A GTC ORF with score 233 to: (ai:7000775056) pneumoniae (or:Pseudomonas aeruginosa) 17058175_f2_75 5438 22009 585 194 115 −4 Drosophila M15765 (sr:drosophila melanogaster (strain oregon r) melanogaster (clone: p19.) pupa cdn) (de:d. melanogaster pen repeats mrna, clone p19.) (nt:orf; putative) 13145780_f2_76 5439 22010 1158 385 213 −17 Klebsiella Contig542A GTC ORF with score 421 to: (ai:7000775152) pneumoniae (or:Pseudomonas aeruginosa) 23572156_f2_79 5440 22011 318 105 16300331_f2_84 5441 22012 669 222 90 −2 Indian corn Y07781 (de:z. mays grp3 mrna for glycine-rich protein.) 12994830_f3_100 5442 22013 1008 335 584 −57 Escherichia P76037 (de:hypothetical 49.8 kd transport protein in coli sapa-aldh intergenic region) 10438755_f3_107 5443 22014 690 229 93 −2 Klebsiella Contig549A GTC ORF with score 108 to: (ai:7000777540) pneumoniae (or:Pseudomonas aeruginosa) 33791658_f3_110 5444 22015 363 120 98 −5 Klebsiella Contig533A GTC ORF with score 504 to: (ai:7000836279) pneumoniae (or:Enterobacter cloacae) 16661633_f3_113 5445 22016 1134 377 566 −55 Pseudomonas AF029714 (de:pseudomonas putida repressor (phan), putida regulatory protein (pham),enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad),phenylacetyl-coa ligase (phac). ring-oxidation . . . 16526025_f3_118 5446 22017 1533 510 1112 −113 Pseudomonas AF029714 (de:pseudomonas putida repressor (phan), putida regulatory protein (pham),enoyl-coa hydratase i (phaa), enoyl-coa hydratase ii (phab),3- hydroxyacyl-coa dehydrogenase (phac), ketothiolase (phad),phenylacetyl-coa ligase (phae). ring-oxidation . . . 5988508_f3_122 5447 22018 969 322 156 −11 Enterobacter CONTIG437 GTC ORF with score 156 to: (ai:7000775107) cloacae (or:Pseudomonas aeruginosa) 1067591_f3_123 5448 22019 921 306 126 −5 Nephila A44112 clavipes 33728216_f3_126 5449 22020 1299 432 402 −38 Klebsiella Contig533A GTC ORF with score 614 to: (ai:7000836323) pneumoniae (or:Enterobacter cloacae) 32526092_f3_130 5450 22021 2556 851 1671 −172 Klebsiella Contig542A GTC ORF with score 1671 to: pneumoniae (ai:7000775115) (or:Pseudomonas aeruginosa) 31687582_f3_131 5451 22022 630 209 767 −76 Pseudomonas U49666 (fn:regulatory protein) (sr:pseudomonas aeruginosa aeruginosa strain=pao1) (de:pseudomonas aeruginosa (orfx), glycerol dfiffusion facilitator(glpf), glycerol kinase (glpk), and glp repressor (glpr) genes,complete cds, and (orfk) gene. partial cds) ( . . . 11907283_f3_132 5452 22023 1548 515 1455 −149 Thermus AB004569 (sr:thermus flavus dna) (ec:2.7.1.30) aquaticus (de:thermus flavus gene for glycerol kinase, (SUBSP. complete cds.) FLAVUS) 31260458_f3_133 5453 22024 981 326 411 −38 Synechococcus U59236 (de:synechococcus pcc7942 ribosomal protein sp. (strain s1 of 30s ribosome (rps1),orf271, orf231, PCC 7942) orf341, carboxyltransferase alpha subunit (acca),orf245, orf227, and gtp cyclohydrolase i (fole) genes, completecds, and orf205 gene, partial cds.) (nt . . . 36225931_f3_141 5454 22025 216 71 107 −6 Bacillus F70041 subtilis/ Bacillus globigii 22156376_f3_146 5455 22026 813 270 153 −11 Klebsiella Contig471A GTC ORF with score 160 to: (ai:7000758711) pneumoniae (or:Pseudomonas aeruginosa) 26298958_f3_147 5456 22027 729 242 129 −5 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 6765791_f3_149 5457 22028 468 155 136 −8 Burkholderia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob cepacia (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 30566509_c1_150 5458 22029 2154 717 361 −32 Klebsiella Contig471A GTC ORF with score 379 to: (ai:7000758947) pneumoniae (or:Pseudomonas aeruginosa) 16531505_c1_152 5459 22030 537 178 155 −10 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32239662_c1_153 5460 22031 1302 433 270 −23 Klebsiella Contig558A GTC ORF with score 113 to: (ai:276132) pneumoniae (or:Caenorhabditis elegans) (sr:caenorhabditis elegans strain=bristol n2) (de:caenorhabditis elegans cosmid f08d12.) 34162657_c1_156 5461 22032 585 194 218 −18 Escherichia B64962 coli 32292031_c1_157 5462 22033 522 173 33403_c1_159 5463 22034 603 200 14062807_c1_165 5464 22035 636 211 99 −2 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 22163931_c1_167 5465 22036 1743 580 421 −40 Klebsiella Contig542A GTC ORF with score 421 to: (ai:7000775152) pneumoniae (or:Pseudomonas aeruginosa) 25781508_c1_170 5466 22037 1728 575 194 −11 Epstein-Barr S27923 virus 4379777_c1_180 5467 22038 648 215 99 −2 human U13194 (fn:transcriptional regulation) (de:human herpesvirus herpesvirus 6 replication origin-binding type 6 HHV-6 protein (hdrfo),partial cds, helicase-primase component (hdrf1), virion protein(hdlf1), putative helicase (hdrf2), putative phosphoprotein(edrf1). replica . . . 36431428_c1_183 5468 22039 1599 532 22932007_c1_188 5469 22040 1542 513 725 −72 Escherichia P37643 (de:region (o440)) coli 21694512_c1_196 5470 22041 456 151 102 −4 malaria Q99319 (sr:,isolate thtn/thailand) (de:merozoite parasite surface antigen 2 precursor (msa-2) (allelic form 3)) 30603955_c2_197 5471 22042 588 195 99 −5 Klebsiella Contig548A GTC ORF with score 121 to: (ai:7000794724) pneumoniae (or:Pseudomonas aeruginosa) 3229201_c2_198 5472 22043 255 84 137 −10 Klebsiella Contig471A GTC ORF with score 137 to: (ai:7000775183) pneumoniae (or:Pseudomonas aeruginosa) 15726066_c2_202 5473 22044 594 197 95 −2 Turnip yellow AF035403 (fn:involved with movement) (de:turnip yellow mosaic virus mosaic blue lake isolate, complete genome.) (nt:overlapping protein) 33789708_c2_205 5474 22045 435 144 97 −5 Klebsiella Contig558A GTC ORF with score 97 to: (ai:7000775190) pneumoniae (or:Pseudomonas aeruginosa) 22050078_c2_210 5475 22046 183 60 7164581_c2_211 5476 22047 957 318 218 −18 Klebsiella Contig475A GTC ORF with score 247 to: (ai:7000838514) pneumoniae (or:Enterobacter cloacae) 605086_c2_212 5477 22048 1641 546 754 −75 Klebsiella Contig542A GTC ORF with score 1671 to: pneumoniae (ai:7000775115) (or:Pseudomonas aeruginosa) 5364783_c2_213 5478 22049 537 178 201 −16 Klebsiella Contig487A GTC ORF with score 402 to: (ai:7000820035) pneumoniae (or:Enterobacter cloacae) 1302_c2_214 5479 22050 912 303 1411 −144 Pseudomonas Q51389 (de:glycerol uptake facilitator protein (glycerol aeruginosa dfiffusion facilitator)) 2082081_c2_215 5480 22051 1557 518 2626 −273 Pseudomonas Q51390 (ec:2.7.1.30) (de:(glycerokinase) (gk)) aeruginosa 16539191_c2_217 5481 22052 681 226 90 −4 longfin squid S56117 (sr:, longfin squid) 14353916_c2_218 5482 22053 1743 580 1761 −181 Pseudomonas P52111 (ec:1.1.99.5) (de:glycerol-3-phosphate aeruginosa dehydrogenase,) 14324033_c2_222 5483 22054 204 67 23851538_c2_223 5484 22055 975 324 689 −68 Escherichia P19797 (de:transcriptional activator protein metr) coli 24087587_c2_225 5485 22056 1497 498 286 −25 Klebsiella Contig541A GTC ORF with score 440 to: (ai:7000809610) pneumoniae (or:Pseudomonas aeruginosa) 34507206_c2_227 5486 22057 354 117 124 −7 Rattus B48013 (cl:proline-rich protein) (sr:, norway rat) norvegicus 7039563_c2_228 5487 22058 843 280 172 −13 Enterobacter CONTIG513 GTC ORF with score 194 to: (ai:7000788489) cloacae (or:Pseudomonas aeruginosa) 12948287_c2_234 5488 22059 903 300 474 −45 Escherichia P77559 (de:hypothetical transcriptional regulator in coli mlc-asr intergenic region) 36120166_c2_242 5489 22060 483 160 182 −14 Enterobacter CONTIG338 GTC ORF with score 574 to: (ai:7501758167) cloacae (or:Klebsiella pneumoniae) 275337_c2_247 5490 22061 789 262 255 −22 Rhodobacter AF084031 (de:rhodobacter sphaeroides strain 2.4.lt sphaeroides putrescine/spermidinetransport atpase pota (pota) gene, partial cds; and dmso reductaseregulatory protein dorx (dorx) and dmso reductase regulatoryprotein dory (dory) genes. complete cds.) 1181627_c3_251 5491 22062 936 311 1632 −168 Pseudomonas P28809 (de:mmsab operon regulatory protein) aeruginosa 24644777_c3_252 5492 22063 183 60 14230137_c3_255 5493 22064 693 230 283 −25 Escherichia P34000 (de:potential acrab operon repressor) coli 21923287_c3_256 5494 22065 1152 383 158 −10 Aspergillus Contig972 GTC ORF with score 158 to: (ai:7000775241) fumigatus (or:Pseudomonas aeruginosa) 14335331_c3_269 5495 22066 432 143 137 −9 Homo sapiens S53363 (sr:, man) (mp:11p15.5-11p15.5) 10430380_c3_270 5496 22067 309 102 296 −26 Klebsiella Contig542A GTC ORF with score 296 to: (ai:7000775255) pneumoniae (or:Pseudomonas aeruginosa) 16275016_c3_272 5497 22068 885 294 1222 −124 Pseudomonas Q51391 (de:glyecrol-3-phosphate regulon repressor) aeruginosa 10822717_c3_273 5498 22069 213 70 150 −10 Pseudomonas P52111 (cc:1.1.99.5) (de:glycerol-3-phosphate aeruginosa dehydrogenase,) 33677166_c3_274 5499 22070 411 136 643 −63 Pseudomonas P52111 (ec:1.1.99.5) (de:glycerol-3-phosphate aeruginosa dehydrogenase,) 33725830_c3_275 5500 22071 462 153 540 −52 Pseudomonas P52112 (de:membrane protein glpm) aeruginosa 25593836_c3_278 5501 22072 540 179 132 −9 Klebsiella Contig534A GTC ORF with score 253 to: (ai:7000827730) pneumoniae (or:Enterobacter cloacae) 16495756_c3_280 5502 22073 648 215 130 −6 Streptomyces L20249 (sr:streptomyces coriofaciens (library: isp coriofaciens 5485) dna) (de:streptomyces coriofaciens beta- ketoacyl synthase homologue gene,partial cds.) (nt:homologous to saccharopolyspora crythraea) 34480280_c3_281 5503 22074 447 148 95 −3 Pseudomonas S29309 aeruginosa 33713166_c3_282 5504 22075 450 149 372 −34 Klebsiella Contig541A GTC ORF with score 530 to: (ai:7000809735) pneumoniae (or:Pseudomonas aeruginosa) 4572558_c3_283 5505 22076 594 197 144 −10 Klebsiella Contig560A GTC ORF with score 241 to: (ai:7000847231) pneumoniae (or:Enterobacter cloacae) 22829561_c3_284 5506 22077 726 241 169 −11 Enterobacter CONTIG509 GTC ORF with score 750 to: (ai:7000763079) cloacae (or:Pseudomonas aeruginosa) 6822663_c3_285 5507 22078 1437 478 289 −25 Enterobacter CONTIG513 GTC ORF with score 289 to: (ai:7000775270) cloacae (or:Pseudomonas aeruginosa) 22163125_c3_288 5508 22079 2013 670 25422837_c3_289 5509 22080 1365 454 190 −14 Klebsiella Contig560A GTC ORF with score 190 to: (ai:7000775274) pneumoniae (or:Pseudomonas aeruginosa) 32673886_c3_290 5510 22081 1311 436 107 −4 Klebsiella Contig117A GTC ORF with score 164 to: (ai:7000757726) pneumoniae (or:Pseudomonas aeruginosa) 34557165_c3_294 5511 22082 696 231 112 −3 infectious Z78205 (de:bovine herpesvirus type 1 ul22-35 genes.) bovine (nt:homolog of icp18.5 of hsv-1) rhinotrachetis virus 29397503_c3_297 5512 22083 492 163 101 −4 Aspergillus v1x13001.x GTC ORF with score 408 to: (ai:113583) fumigatus (or:Saccharomyces cerevisiae) (de:(yjr151c) (pn:hypothetical 118:similarity to mucin proteins, yk1224c, sta1p) (gn:j2223) (gtcfc:11.1) (ec:) (yj9p_yeast) (keggfc:11.2) (sgdfc:9.1.0) (db:gtc-saccharomyces cerevisiae)) 32161681_f1_1 5513 22084 1347 448 236 −17 Bacillus AF008220 (de:bacillus subtilis rrnb-dnab genomic subtilis/ region.) (nt:similarity to hypothetical protein Bacillus f400 from e.) globigii 16881455_f1_7 5514 22085 483 160 111 −7 Klebsiella Contig462A GTC ORF with score 111 to: (ai:7000775290) pneumoniae (or:Pseudomonas aeruginosa) 4492275_f1_11 5515 22086 1170 389 394 −36 Bacillus P40402 (de:hypothetical 41.8 kd protein (orfm)) subtilis/ Bacillus globigii 17082792_f1_14 5516 22087 444 147 116 −7 Aspergillus Contig9506 GTC ORF with score 139 to: (ai:116274) fumigatus (or:Caenorhabditis elegans) (de:hypothetical 84.3 kd protein zk945.10 in chromosome ii) 32682262_f1_15 5517 22088 582 193 119 −5 Caenorhabditis Z81050 (de:caenorhabditis elegans cosmid c50b6, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 22542593_f1_29 5518 22089 591 196 141 −10 Klebsiella Contig446A GTC ORF with score 188 to: (ai:7000842334) pneumoniae (or:Enterobacter cloacae) 7042840_f1_31 5519 22090 693 230 131 −7 Klebsiella Contig446A GTC ORF with score 185 to: (ai:7000760769) pneumoniae (or:Pseudomonas aeruginosa) 12370336_f1_35 5520 22091 909 302 706 −69 Escherichia P32159 (de:hypothetical 32.9 kd protein in cpxa-pfka coli intergenic region) 6932787_f1_39 5521 22092 408 135 16268830_f1_40 5522 22093 489 162 212 −17 Enterobacter CONTIG397 GTC ORF with score 327 to: (ai:7501766991) cloacae (or:Klebsiella pneumoniae) 22867081_f1_42 5523 22094 1104 367 499 −48 Streptomyces AL031515 (de:streptomyces coelicolor cosmid 5c7.) coelicolor (nt:sc5c7.08, unknown, : 346 aa; similar to) 16258541_f1_48 5524 22095 1938 645 96 −2 Klebsiella Contig421A GTC ORF with score 96 to: (ai:7000775331) pneumoniae (or:Pseudomonas aeruginosa) 26697680_f1_56 5525 22096 918 305 293 −26 Cyano- P72965 (sr:pcc6803,) (ec:2.5.1.3) bacterium (de:pyrophosphorylase) (tmp-ppase) (thiamin- synechocystis phosphate synthase)) 22141692_f1_57 5526 22097 1197 398 249 −21 Klebsiella Contig443A GTC ORF with score 249 to: (ai:7000775340) pneumoniae (or:Pseudomonas aeruginosa) 35599193_f1_58 5527 22098 642 213 931 −93 Pseudomonas S57899 aeruginosa 29777205_f1_−64 5528 22099 648 215 435 −41 Haemophilus P71335 (de:hypothetical protein hi0004) influenzae 36062931_f1_68 5529 22100 1137 378 128 −7 Klebsiella Contig489A GTC ORF with score 128 to: (ai:7000775351) pneumoniae (or:Pseudomonas aeruginosa) 32157666_f1_73 5530 22101 1041 346 176 −13 Klebsiella Contig489A GTC ORF with score 176 to: (ai:7000775356) pneumoniae (or:Pseudomonas aeruginosa) 22163916_f1_75 5531 22102 855 284 155 −8 Micrococcus JQ0405 luteus 25417218_f1_76 5532 22103 675 224 120 −5 Achromobacter A61183 georgio- politanum 29947915_f1_78 5533 22104 201 66 16891462_f1_82 5534 22105 321 106 100 −5 Medicago X99467 (sr:barrel medic) (de:m. truncatula enod20 truncatula gene.) 33844783_f1_83 5535 22106 1245 414 32525937_f1_87 5536 22107 1083 360 421 −40 Enterobacter CONTIG198 GTC ORF with score 626 to: (ai:7501728044) cloacae (or:Klebsiella pneumoniae) 23729561_f1_94 5537 22108 1176 391 331 −30 Enterobacter CONTIG389 GTC ORF with score 331 to: (ai:7000775377) cloacae (or:Pseudomonas aeruginosa) 2382961_f1_107 5538 22109 975 324 180 −14 Clostridium Contig232H GTC ORF with score 370 to: (ai:7500956031) acetobutylicum (or:Borrelia burgdorferi) (sr:, lyme disease spirochete) 9891456_f2_113 5539 22110 1557 518 603 −59 Enterobacter CONTIG447 GTC ORF with score 1123 to: cloacae (ai:7501774336) (or:Klebsiella pneumoniae) 16505066_f2_115 5540 22111 648 215 93 −3 Klebsiella Contig449A GTC ORF with score 147 to: (ai:1500692508) pneumoniae (or:Boreogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12601056_f2_123 5541 22112 1164 387 5159781_f2_124 5542 22113 1344 447 198 −12 Gallus gallus I50694 (cl:collagen alpha 1(i) chain:fibrillar collagen domesticus carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 21688877_f2_128 5543 22114 513 170 35650207_f2_130 5544 22115 1416 471 14948383_f2_135 5545 22116 183 60 12973783_f2_143 5546 22117 249 82 106 −5 Nannocystis U66220 (de:nannocystis exedens unknown protein, exedens partial cds and microsatellitesequence 7a140.) (nt:orf1) 14963277_f2_151 5547 22118 423 140 113 −6 southern root- U40766 (sr:southern root-knot nematode) knot nematode (de:meloidogyne incognita cuticle collagen col- 1 (col-1) mrna, completecds.) (nt:cuticle collagen; method: conceptual translation) 16145837_f2_153 5548 22119 2109 702 422 −39 Klebsiella Contig121A GTC ORF with score 422 to: (ai:7000775436) pneumoniae (or:Pseudomonas aeruginosa) 13025092_f2_157 5549 22120 702 233 154 −9 Epstein-Barr M17294 (sr:human herpesvirus 4 (clone: h6) dna) virus (de:epstein-barr virus bamhi-h (bhlfl) region encoding an orf, partialcds.) (nt:orf; putative) 6769540_f2_162 5550 22121 1020 339 146 −7 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 29947155_f2_165 5551 22122 1464 487 2182 −226 Pseudomonas P48247 (ec:5.4.3.8) (de:(glutamate-1-semialdehyde aeruginosa aminotransferase) (gsa-at)) 12987532_f2_170 5552 22123 1266 421 134 −5 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 5157693_f2_173 5553 22124 1545 514 850 −85 Escherichia P23930 (ec:2.3.1.—) (de:(copper homeostasis protein coli cute)) 2448287_f2_174 5554 22125 438 145 116 −6 Caenorhabditis Z79694 (de:caenorhabditis elegans cosmid c15a11, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 35735942_f2_175 5555 22126 564 187 101 −2 Homo sapiens AB014591 (sr:homo sapiens adult male brain cdna to mrna, clone_:pbluescripti) (de:homo sapiens mrna for kiaa0691 protein, complete cds.) 33229668_f2_176 5556 22127 2742 913 2672 −278 Escherichia P07813 (ec:6.1.1.4) (de:leucyl-trna synthetase, (leucine- coli trna ligase) (leurs)) 11760410_f2_177 5557 22128 690 229 2079157_f2_178 5558 22129 600 199 106 −6 African clawed P24056 (sr:,african clawed frog) (de:sperm-specific frog basic nuclear protein sp4) 14320413_f2_184 5559 22130 411 136 131 −9 Acinetobacter CONTIG158 GTC ORF with score 212 to: (ai:7501728046) baumannii C (or:Klebsiella pneumoniae) 22673528_f2_192 5560 22131 1887 628 203 −15 Klebsiella Contig179A GTC ORF with score 203 to: (ai:7000775475) pneumoniae (or:Pseudomonas aeruginosa) 33791592_f2_195 5561 22132 2721 906 184 −11 Klebsiella Contig456A GTC ORF with score 245 to: (ai:7000822167) pneumoniae (or:Enterobacter cloacae) 10942913_f2_197 5562 22133 405 134 113 −7 Caenorhabditis Z70718 (de:caenorhabditis elegans cosmid c04g2, elegans complete sequence.) (nt:predicted using genefinder; cdna est embl:d65901) 32133280_f2_200 5563 22134 555 184 130 −6 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluesriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 4879678_f2_201 5564 22135 744 247 128 −5 Homo sapiens X65120 (fn:structural short chain collagen of cartilage) (sr:human) (de:h. sapiens co110a1 gene for alpha 1 (x) collagen.) 14978780_f3_211 5565 22136 657 218 132 −5 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda-1102) virus (type 6/ ic2hom mrna, complete cds.) (nt:similar to the strain immediate-early 2 protein of human) Uganda-1102) 25678841_f3_213 5566 22137 1401 466 312 −28 Bacillus A69973 (cl:hypothetical protein yddq) subtilis/ Bacillus globigii 35672576_f3_214 5567 22138 1992 663 126 −5 Escherichia B64873 (mp:28 min) coli 32526082_f3_215 5568 22139 501 166 187 −14 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 16047908_f3_217 5569 22140 348 115 94 −4 Pseudomonas S29309 aeruginosa 14648311_f3_219 5570 22141 762 253 35369003_f3_221 5571 22142 798 265 1382702_f3_222 5572 22143 2481 826 143 −6 Dichelobacter U20246 (de:dichelobacter nodosus strain a198 vrl gene nodosus locus, completesequence.) (nt:orf1130; vrls) 24253802_f3_224 5573 22144 1521 506 106 −3 Bacillus G69754 subtilis/ Bacillus globigii 1067208_f3_233 5574 22145 228 75 4347900_f3_243 5575 22146 447 148 31660405_f3_244 5576 22147 993 330 127 −5 Nephila A44112 clavipes 33847793_f3_245 5577 22148 327 108 103 −4 infectious Z78205 (de:bovine herpesvirus type 1 ul22-35 genes.) bovine (nt:very large tegument protein) rhinotracheitis virus 23630200_f3_247 5578 22149 543 180 344 −31 Ralstonia X91878 (de:a. eutrophus pdhr, pdhe and ampc genes.) eutropha 32220412_f3_248 5579 22150 297 98 12369758_f3_249 5580 22151 489 162 152 −10 Drosophila P49456 (sr:,fruit fly) (de:tropomyosin 1, fusion protein melanogaster 34) 34492326_f3_251 5581 22152 1668 555 135 −6 mice|C57BL/ P05143 (sr:,mouse) (de:proline-rich protein mp-3 6xCBA (fragment)) CaJ hybrid 9869541_f3_257 5582 22153 537 178 152 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 22301692_f3_259 5583 22154 1368 455 154 −10 Klebsiella Contig479A GTC ORF with score 325 to: (ai:7000801275) pneumoniae (or:Pseudomonas aeruginosa) 26769803_f3_260 5584 22155 2079 692 365 −33 Haemophilus P44697 (ec:2.7.4.7) (de:(hmp-p kinase)). influenzae 35266681_f3_261 5585 22156 630 209 102 −5 longfin squid S56117 (sr:, longfin squid) 12585943_f3_265 5586 22157 1509 502 2280 −236 Pseudomonas Q51470 (de:hypothetical 50.0 kd protein in hem1 aeruginosa 3′region (orf2) 12758293_f3_266 5587 22158 1191 396 1014 −102 Escherichia P77349 (de:phoh-like protein) coli 35829127_f3_268 5588 22159 909 302 706 −69 Escherichia P77392 (de:hypothetical 33.3 kd protein in cute-asnb coli intergenic region) 23521057_f3_269 5589 22160 570 189 101 −3 Pseudomonas A36128 aeruginosa 16027043_f3_272 5590 22161 774 257 90 −1 Canadian hard P18573 (sr:,wheat) (de:alpha/beta-gliadin mm1 winter wheat precursor (prolamin)) 11210205_f3_274 5591 22162 588 195 178 −12 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x precursor) herpesvirus type 1 EVH-1 24089531_f3_275 5592 22163 1221 406 420 −39 Escherichia P28630 (ec:2.7.7.7) (de:dna polymerase iii, delta coli subunit,) 36582191_f3_279 5593 22164 1443 480 459 −43 Haemophilus AB002668 (sr:actinobacillus actinomycetemcomitans actinomyce- (strain:y4) dna) (de:actinobacillus temcomitans actinomycetemcomitans dna for glycosyltransferase,lytic transglycosylase, dtdp- 4-rhamnose reductase. complete cds.) 24651662_f3_282 5594 22165 915 304 393 −36 Erwinia AF057064 (fn:regulate multiple virulence determinants) carotovora (de:erwinia carotovora subsp. atroseptica hexa subsp. (hexa) gene, completecds.) (nt:similar to lysr) atroseptica 33620413_f3_283 5595 22166 825 274 313 −28 Klebsiella Contig068A GTC ORF with score 313 to: (ai:7000775566) pneumoniae (or:Pseudomonas aeruginosa) 7319457_f3_284 5596 22167 645 214 201 −16 Enterobacter CONTIG231 GTC ORF with score 799 to: (ai:7501730445) cloacae (or:Klebsiella pneumoniae) 1971938_f3_285 5597 22168 576 191 310 −28 Klebsiella Contig243A GTC ORF with score 799 to: (ai:7000814858) pneumoniae (or:Enterobacter cloacae) 30163306_f3_290 5598 22169 492 163 114 −6 malaria parasite U72957 (sr:malaria parasite) (de:plasmodium falciparum merozoite surface protein 2 (msp-2) gene,partial cds.) (nt:allele: 3d7) 32690966_f3_295 5599 22170 528 175 180 −14 Klebsiella Contig489A GTC ORF with score 418 to: (ai:7000822187) pneumoniae (or:Enterobacter cloacae) 31532182_f3_297 5600 22171 1611 536 293 −25 Enterobacter CONTIG250 GTC ORF with score 293 to: (ai:7000775580) cloacae (or:Pseudomonas aeruginosa) 3132807_f3_298 5601 22172 1332 443 161 −9 Rhodococcus AF003947 (ec:3.1.1.24:4.1.1.44) (de:rhodococcus opacus opacus succinyl coa:3-oxoadipate coa transferasesubunit homolog (pcai') gene, partial cds, protocatechuatedioxygenase beta subunit (pcah), protocatechuate dioxygenase alphasubunit (pcag) 3-carb . . . 16816625_f3_301 5602 22173 1239 412 245 −20 Escherichia P30149 (de:hypothetical 26.3 kd protein in arac-tbpa coli intergenic region (orf99)) 16839040_f3_303 5603 22174 327 108 25447152_c1_307 5604 22175 861 286 387 −36 Acinetobacter CONTIG217 GTC ORF with score 387 to: (ai:7000775590) baumannii C (or:Pseudomonas aeruginosa) 16464182_c1_312 5605 22176 2118 705 371 −33 Escherichia P52085 (de:hypothetical 24.5 kd protein in phpb-hola coli intergenic region (orfuu)) 26442192_c1_313 5606 22177 399 132 115 −6 Araneus U47855 (de:araneus diadematus fibroin-3 (adf-3) mrna, diadematus partial cds.) 35260340_c1_317 5607 22178 1269 422 1033 −104 Escherichia P15035 (de:rod shape-determining protein roda) coli 10048277_c1_323 5608 22179 822 273 111 −6 Klebsiella Contig243A GTC ORF with score 111 to: (ai:7000775606) pneumoniae (or:Pseudomonas aeruginosa) 12320432_c1_326 5609 22180 1017 338 1075 −109 Escherichia L07636 (sr:escherichia coli (sub_strain w3110, coli strain k-12) (libr: kohar) (de:e. coli lipoic acid biosynthesis lipa, lipb, and orfs 1, 2 and 3 genes. complete cds; daca gene. 3′ end.) 9862888_c1_330 5610 22181 921 306 292 −27 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome segment 49/162.) (nt:rv1124, (mtcy22g8.13), len: 316. ephc, similar to) 16501880_c1_346 5611 22182 651 216 223 −19 Klebsiella Contig489A GTC ORF with score 223 to: (ai:7000775629) pneumoniae (or:Pseudomonas aeruginosa) 29376062_c1_351 5612 22183 477 158 16875833_c1_356 5613 22184 753 250 114 −3 Nephila AF027735 (de:nephila clavipes minor ampullate silk clavipes protein misp1 mrna, partialcds.) 15883561_c1_360 5614 22185 1512 503 107 −3 Rattus A54889 (cl:beta-galactoside-binding lectin) (sr:, norvegicus norway rat) 16299216_c1_361 5615 22186 405 134 112 −5 Alphaherpes- P33485 (sr:kaplan,prv) (de:probable nuclear antigen) virus pseudorabies virus PRV 16664517_c1_363 5616 22187 2187 728 1377 −142 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 33/162.) (nt:rv0672, (mtci376.02c), len: 545, fade8, probable) 16666418_c1_369 5617 22188 1224 407 31769761_c1_370 5618 22189 669 222 621 −60 Escherichia P75966 (de:hypothetical 23.7 kd protein in trmu-icda coli intergenic region) 11064408_c1_375 5619 22190 630 209 117 −4 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16927333_c1_376 5620 22191 951 316 106 −3 Nephila U20329 (fn:spider silk) (de:nephila clavipes spidroin 1 clavipes mrna, partial cds.) (nt:fibroin) 4023966_c1_377 5621 22192 519 172 252 −21 Pseudomonas AF036343 (fn:catalyzes the and dependent oxidation of) pseudo- (de:pseudomonas pseudoalcaligenes 2- alcaligenes aminomuconic acid semialdehydedehydrogenase (amnc) gene, complete cds.) 34652_c1_378 5622 22193 2631 876 1234 −125 Rhizobium U49051 (de:sinorhizobium meliloti putative deah meliloti family helicase helo gene,complete cds.) (megaplasmid (nt:putative helicase, belonging to the deah pRME41B family) SYM 10360627_c1_386 5623 22194 189 62 16661641_c1_392 5624 22195 690 229 121 −4 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 12993792_c1_394 5625 22196 1011 336 107 −3 Orf virus B34768 13145906_c1_396 5626 22197 1434 477 14167590_c1_399 5627 22198 537 178 200 −16 Cyano- S76526 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 33697517_c1_401 5628 22199 453 150 178 −14 Klebsiella Contig525A GTC ORF with score 178 to: (ai:7000775684) pneumoniae (or:Pseudomonas aeruginosa) 34239067_c1_403 5629 22200 1614 538 108 −3 no gb Y15174 (de:human papillomavirus type 76 e6, e7, e1, taxonomy e2, e4, l2, and l1 genes.) (nt:putative) match 31298758_c2_405 5630 22201 582 193 96 −3 Enterobacter CONTIG499 GTC ORF with score 96 to: (ai:7000775688) cloacae (or:Pseudomonas aeruginosa) 9802080_c2_412 5631 22202 1299 432 1074 −108 Thermus ruber AF082661 (cc:1.2.1.41) (de:meiothermus ruber gamma- glutamyl phosphate reductase (proa) gene,complete cds ) 34460257_c2_414 5632 22203 420 139 281 −24 Escherichia P05848 (de:hypothetical 11.6 kd protein in mrda-phpb coli intergenic region) 15808291_c2_415 5633 22204 774 257 157 −9 Pseudomonas AF036343 (fn:catalyzes the and dependent oxidation of) pseudo- (de:pseudomonas pseudoalcaligenes 2- alcaligenes aminomuconic acid semialdehydedehydrogenase (amnc) gene, complete cds.) 12989405_c2_421 5634 22205 939 312 118 −4 Nephila AF027973 (de:nephila clavipes flagelliform silk protein clavipes (flag) mrna, partialcds.) 26228181_c2_422 5635 22206 1185 394 887 −89 Escherichia P08506 (ec:3.4.16.4) (de:(dd-carboxypeptidase) (pbp- coli 6)) 32547691_c2_423 5636 22207 693 230 576 −56 Haemophilus H64043 influenzae 22784531_c2_428 5637 22208 768 255 133 −7 Enterococcus CONTIG108 GTC ORF with score 1137 to: faecalis (ai:7000759121) (or:Pseudomonas aeruginosa) 36143903_c2_434 5638 22209 1485 494 4005008_c2_438 5639 22210 480 159 9847877_c2_439 5640 22211 792 263 204 −16 Haemophilus P44292 (de:hypothetical protein hi1701) influenzae 29980342_c2_443 5641 22212 822 273 211 −17 Klebsiella Contig489A GTC ORF with score 397 to: (ai:7000820304) pneumoniae (or:Enterobacter cloacae) 33603328_c2_444 5642 22213 1206 401 507 −49 Klebsiella Contig489A GTC ORF with score 974 to: (ai:7000820328) pneumoniae (or:Enterobacter cloacae) 4118956_c2_445 5643 22214 1524 507 819 −82 Klebsiella Contig489A GTC ORF with score 930 to: (ai:7000820309) pneumoniae (or:Enterobacter cloacae) 32692793_c2_451 5644 22215 882 293 97 −1 Caenorhabditis U61288 (de:caenorhabditis elegans ce mrna, partial elegans cds.) (nt:similar to theoretical r08b4.1 protein.;) 30746066_c2_452 5645 22216 2436 811 632 −61 Cyano- S75136 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 21525417_c2_453 5646 22217 687 228 118 −7 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv bacterium complete genome; segment 150/162.) tuberculosis (nt:rv3557c, (mtcy06g11.04c), len: 200 aa. probable) 35242632_c2_454 5647 22218 822 273 111 −3 Acanthamoeba P19706 (sr:,amoeba) (de:myosin heavy chain ib castellanii (myosin heavy chain il)) 34182966_c2_455 5648 22219 1623 540 16072715_c2_456 5649 22220 642 213 22462686_c2_463 5650 22221 600 199 127 −8 Enterobacter CONTIG455 GTC ORF with score 127 to: (ai:7000775746) cloacae (or:Pseudomonas aeruginosa) 33713186_c2_468 5651 22222 561 186 407 −37 Rhizobium U49051 (de:sinorhizobium meliloti putative deah meliloti family helicase helo gene,complete cds.) (megaplasmid (nt:putative helicase, belonging to the deah pRME41B family) SYM) 24484418_c2_475 5652 22223 234 77 4898957_c2_476 5653 22224 654 217 465 −44 Escherichia AB011549 (sr:escherichia coli (str:o157:h7, sub_str:rimd coli 0509952) (de:escherichia coli plasmid po157 dna, complete sequence.) (nt:hypothetical protein; similar to pir accession) 34552025_c2_477 5654 22225 270 89 295 −26 Escherichia Y07545 (de:e. coli plasmid po157 dna, 5′-region of the coli ehec-hemolysin operon.) 25978536_c2_480 5655 22226 384 127 11051426_c2_488 5656 22227 252 83 10057791_c2_494 5657 22228 879 292 262 −24 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 48/162.) (nt:rv1050, (mtv017.03), len: 301. probable) 6723841_c2_495 5658 22229 873 290 112 −3 no gb U52064 (de:kaposi's sarcoma-associated herpes-like taxonomy virus orf73 homolog gene,complete cds.) match (nt:herpesvirus saimiri orf73 homolog) 36064513_c2_500 5659 22230 792 263 522 −50 Klebsiella Contig462A GTC ORF with score 522 to: (ai:7000775783) pneumoniae (or:Pseudomonas aeruginosa) 24492192_c3_508 5660 22231 900 299 12203332_c3_511 5661 22232 498 165 104 −3 Homo sapiens A53253 (cl:map2/tau repeat homology) (sr:, man) 32675665_c3_519 5662 22233 564 187 505 −48 Escherichia P05850 (de:hypothetical 17.3 kd protein in mrda-phpb coli intergenic region) 12163280_c3_520 5663 22234 1953 650 1339 −137 Escherichia P08150 (de:penicillin-binding protein 2 (pbp-2)) coli 24870675_c3_523 5664 22235 1194 397 696 −68 Escherichia P41052 (ec:3.2.1.—) (de:(murein hydrolase b) (35 kd coli soluble lytic transglycosylase) (slt35)) 11844183_c3_524 5665 22236 957 318 310 −28 Helicobacter C64716 pylori 14964417_c3_526 5666 22237 474 157 151 −11 Acinetobacter CONTIG173 GTC ORF with score 151 to: (ai:7000775809) baumannii C (or:Pseudomonas aeruginosa) 13089066_c3_538 5667 22238 1212 403 33724207_c3_539 5668 22239 3321 1106 1208 −123 Klebsiella Contig489A GTC ORF with score 2227 to: pneumoniae (ai:7000822193) (or:Enterobacter cloacae) 36463555_c3_542 5669 22240 186 61 16198336_c3_543 5670 22241 1914 637 382 −35 Klebsiella Contig489A GTC ORF with score 442 to: (ai:7000820315) pneumoniae (or:Enterobacter cloacae) 17042291_c3_545 5671 22242 738 245 125 −5 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 22911416_c3_554 5672 22243 270 89 91 −4 Arabidopsis AJ002378 (sr:thale cress) (de:arabidopsis thaliana mrna thaliana for rszp22 splicing factor.) (nt:zn-finger containing arg/ser-rich 22kd splicing) 26620136_c3_557 5673 22244 1164 387 825 −82 Klebsiella Contig443A GTC ORF with score 825 to: (ai:7000775840) pneumoniae (or:Pseudomonas aeruginosa) 33885201_c3_558 5674 22245 573 190 98 −2 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 34491258_c3_560 5675 22246 444 147 99 −3 bovine Z84818 (de:bovine herpesvirus type 4 gene encoding herpesvirus gp80.) type 4 BHV-4 3227056_c3_565 5676 22247 1428 475 98 −3 Klebsiella Contig546A GTC ORF with score 127 to: (ai:7000780553) pneumoniae (or:Pseudomonas aeruginosa) 32510418_c3_566 5677 22248 444 147 105 −6 Haemophilus P45083 (de:hypothetical protein hi1161) influenzae 34660888_c3_567 5678 22249 1554 517 1306 −133 Escherichia P15272 (ec:3.2.2.4) (de:amp nucleosidase,) coli 23956658_c3_574 5679 22250 912 303 116 −4 Cyano- S74632 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) bacterium synechocystis 4085153_c3_578 5680 22251 1221 406 3164708_c3_579 5681 22252 339 112 417 −39 Pseudomonas U00100 (de:pseudomonas aeruginosa insertion aeruginosa sequence is222, dna sequence.) 23838456_c3_591 5682 22253 1263 420 16995827_c3_595 5683 22254 435 144 106 −4 Fundulus Q90508 (sr:,killifish:mummichog) (de:phosvitin (pv); heteroclitus lipovitellin 2 (lv2))) 31691637_c3_602 5684 22255 1383 460 1084 −110 Escherichia P25888 (de:putative atp-dependent rna helicase rhle) coli 1277056_f1_14 5685 22256 2190 729 6254588_f1_17 5686 22257 1665 554 10598408_f1_29 5687 22258 483 160 107 −4 equine D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus (de:equine herpesvirus 1 dna for tegument type 1 EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 2598966_f1_41 5688 22259 2136 711 139 −5 common Y11592 (sr:common cuttlefish) (de:s. officinalis mrna cuttlefish for peroxidase.) 12987805_f1_52 5689 22260 819 272 25989582_f1_53 5690 22261 672 223 144 −8 Aspergillus Contig8555 GTC ORF with score 214 to: (ai:7000795204) fumigatus (or:Pseudomonas aeruginosa) 14062886_f1_57 5691 22262 381 126 535 −51 Pseudomonas AF060193 (de:pseudomonas aeruginosa pigacde operon, aeruginosa complete sequence;hypothetical pigb (pigb) gene, complete cds.) 24089656_f1_59 5692 22263 1821 606 109 −3 Aspergillus v1x1fj93.x GTC ORF with score 429 to: (ai:177837) fumigatus (or:Zea mays) (sr:, maize) 31897652_f1_65 5693 22264 879 292 112 −3 Homo sapiens AF046873 (sr:human) (de:homo sapiens synapsin iiia mrna, complete cds.) (nt:synaptic vesicle protein) 2603955_f2_74 5694 22265 1890 629 16270441_f2_85 5695 22266 930 309 102 −4 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 401162.) (nt:rv0833, (mtv043.25), len: 749. mycobacterium) 26816005_f2_89 5696 22267 858 285 132 −7 Aspergillus Contig8378 GTC ORF with score 102 to: (ai:179628) fumigatus (or:Saccharomyces cerevisiae) (sr:baker's yeast) (de:s. cerevisiae chromosome iv left arm (eu) dna segment (36687 bp).) 22911293_f2_90 5697 22268 468 155 114 −7 Caenorhabditis Z70718 (de:caenorhabditis elegans cosmid c04g2, elegans complete sequence.) (nt:predicted using genefinder; cdna est embl:d65901) 36463193_f2_98 5698 22269 414 137 104 −6 Aspergillus Contig6322 GTC ORF with score 120 to: (ai:1500692508) fumigatus (or:Boreogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31875693_f2_99 5699 22270 1971 656 147 −6 Acanthamoeba P10569 (sr:,amoeba) (de:myosin ic heavy chain) castellanii 16275458_f2_104 5700 22271 576 191 123 −5 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33718932_f2_106 5701 22272 363 120 126 −7 Chinese oak D83241 (sr:antheraea pernyi final instar larvae silkmoth posterior silkglands cdna t) (de:silk moth; silkworm final instar larvae posterior silkglands mrnafor antheraea pernyi fibroin, partial cds.) 31878326_f2_107 5702 22273 837 278 180 −11 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda-1102) virus ie2hom mrna, complete cds.) (nt:similar to the (type 6/strain immediate-early 2 protein of human) Uganda-1102) 14938166_f2_112 5703 22274 693 230 121 −6 Klebsiella P15749 (de:protein pulj)) pneumoniae 30349033_f2_116 5704 22275 708 235 140 −6 Escherichia D90774 (sr:escherichia coli (strain:k12) dna, coli clone_lib:kohara lambda minise) (de:e. coli genomic dna kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 34197013_f2_118 5705 22276 735 244 131 −5 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty-of- 6xCBA/ prolines-101 mrna, complete cds.) (nt:binds to CaJ hybrid several sh3 domain containing proteins) 12978958_f2_121 5706 22277 759 252 112 −3 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia(mia) castellanii gene, complete cds.) (nt:myosin-i) 11725212_f2_123 5707 22278 2160 719 1178 −121 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 144/162.) (nt:rv3370c, (mtv004.28c), len: 1079, dnae, probable) 24885083_f3_125 5708 22279 2085 694 31900701_f3_135 5709 22280 360 119 102 −6 Aspergillus Contig6847 GTC ORF with score 146 to: (ai:175201) fumigatus (or:Chlamydomonas reinhardtii) (de:chlamydomonas reinhardtii vsp-3 mrna, complete cds.) (nt:amino acid feature: rod protein domain. aa 266 . . . ) 16822705_f3_136 5710 22281 492 163 105 −3 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 25837587_f3_142 5711 22282 4230 1409 123 −3 Chinese oak AF083334 (sr:chinese oak silkmoth) (de:antheraea pernyi silkmoth fibroin gene, complete cds.) 651583_f3_143 5712 22283 1152 383 184 −12 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 35/162.) (nt:rv0747, (mtv041.21), len: 801. member of pgrs) 32039793_f3_145 5713 22284 1548 515 100 −2 Rhizobium P28155 (sr:,biovar viciae) (de:hydrogenase leguminosarum expression/formation protein hypb) 1409831_f3_146 5714 22285 438 145 141 −10 Pseudomonas P24564 (de:hypothetical 19.5 kd protein in pilt region aeruginosa (orf6)) 16973908_f3_154 5715 22286 1035 344 228 −17 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22522882_f3_158 5716 22287 624 207 123 −8 Aeromonas P31737 (de:general secretion pathway protein i hydrophila precursor) 15722917_f3_164 5717 22288 549 182 96 −2 Homo sapiens AC004079 (sr:information) (de:homo sapiens pac clone dj0167f23 from 7p15, complete sequence.) (nt:human hoxa3; 95% similarity to e307530) 4768816_f3_167 5718 22289 795 264 15802293_f3_168 5719 22290 2610 869 412 −49 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 144/162.) (nt:rv3370c, (mtv004.28c), len: 1079, dnae, probable) 36058142_c1_180 5720 22291 1515 504 6289700_c1_182 5721 22292 669 222 1002 −101 Pseudomonas AF060193 (de:pseudomonas aeruginosa pigacde operon, aeruginosa complete sequence;hypothetical pigb (pigb) gene, complete cds.) 35337957_c1_184 5722 22293 891 296 1192 −121 Pseudomonas AF060193 (de:pseudomonas aeruginosa pigacde operon, aeruginosa complete sequence;hypothetical pigb (pigb) gene, complete cds.) (nt:pigc) 2347136_c1_192 5723 22294 504 167 409 −38 Pseudomonas Q00514 (de:pdda)) aeruginosa 25567708_c1_193 5724 22295 936 311 99 −1 human U13194 (fn:transcriptional regulation) (de:human herpesvirus herpesvirus 6 replication origin-binding type 6 HHV-6 protein (hdrfo),partial cds, helicase-primase component (hdrf1), virion protein(hdlf1), putative helicase (hdrf2), putative phosphoprotein(edrf1). replica . . . 35832712_c1_194 5725 22296 1245 414 35828958_c1_195 5726 22297 2988 995 789 −78 Erwinia Q01565 (de:secretion protein outd)) chrysanthemi 13011656_c1_200 5727 22298 711 236 179 −12 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia (mia) castellanii gene, complete cds.) (nt:myosin-i) 36350041_c1_201 5728 22299 528 175 158 −12 Klebsiella Contig446A GTC ORF with score 189 to: (ai:7000797627) pneumoniae (or:Pseudomonas aeruginosa) 25677091_c1_210 5729 22300 2328 775 114 −3 Mycobacterium AF034152 (de:mycobacterium smegmatis exochelin gene smegmatis cluster, exit(exit) andfxbb (fxbb) genes, complete cds; and fxbc (fxbc) gene, partial cds.) (nt:abc transporter; this abc transporter probably) 33839582_c1_216 5730 22301 4647 1548 24725750_cl_220 5731 22302 1053 350 101 −2 Homo sapiens S53362 (sr:,man) (mp:11p15.5-11p15.5) 16925715_c1_223 5732 22303 603 200 125 −5 Canis A45195 (cl:guanylate cyclase catalytic domain familiaris homology) (sr:, dog) 31269466_c2_226 5733 22304 390 129 115 −6 Caenorhabditis Z81503 (de:caenorhabditis elegans cosmid f14f7, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 5339580_c2_232 5734 22305 468 155 112 −5 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin gene domesticus coding for phosvitin, exons 23 and24.) 10822332_c2_250 5735 22306 1062 353 281 −24 Pseudomonas Q00518 (de:general secretion pathway protein k) aeruginosa 13001907_c2_252 5736 22307 1032 343 29766340_c2_257 5737 22308 600 199 105 −3 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 HHV-6 major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 22526418_c2_258 5738 22309 2265 754 848 −85 Erwinia P31705 (de:outf)) carotovora 32051030_c2_259 5739 22310 1497 498 1892 −195 Pseudomonas AF047381 (fn:cleaves esters of organic compounds and) aeruginosa (ec:3.1.3.1) (de:pseudomonas aeruginosa alkaline phosphatase (phoa) gene, completecds.) (nt:phosphomonoesterase; phosphodiesterase; low) 35550436_c2_263 5740 22311 297 98 16308531_c2_264 5741 22312 4941 1646 36354552_c2_270 5742 22313 585 194 116 −7 Klebsiella Contig554A GTC ORF with score 324 to: (ai:7000842168) pneumoniae (or:Enterobacter cloacae) 10589211_c2_278 5743 22314 549 182 112 −4 Saccharomyces P47179 (sr:,baker's yeast) (de:precursor) cerevisiae 9895957_c2_279 5744 22315 438 145 139 −8 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26603178_c2_281 5745 22316 609 202 95 −2 Streptococcus AF064540 (de:streptococcus pyogenes c5a peptidase pyogenes (scpa) gene, partial cds;insertion sequence is1562 putative transposase gene complete cds;and protein sic (sic) gene partial cds.) 11126537_c2_282 5746 22317 1686 561 128 −5 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 20738906_c2_283 5747 22318 1854 617 255 −21 Pseudomonas P50598 (de:tolq protein) aeruginosa 32680191_c2_284 5748 22319 1143 380 136 −6 Helicobacter E64687 pylori 7205467_c3_285 5749 22320 2115 704 99 −4 Enterobacter CONTIG465 GTC ORF with score 99 to: (ai:7000776175) cloacae (or:Pseudomonas aeruginosa) 26586650_c3_294 5750 22321 1278 425 894 −89 Pseudomonas AF060193 (fn:regulatory component of two-component) aeruginosa (de:pseudomonas aeruginosa pigacde operon, complete sequence;hypothetical pigb (pigb) gene, complete cds.) (nt:pigd) 24502308_c3_295 5751 22322 1023 340 1604 −165 Pseudomonas AF060193 (fn:component of two-component regulatory aeruginosa system) (de:pseudomonas aeruginosa pigacde operon, complete sequence;hypothetical pigb (pigb) gene, complete cds.) (nt:pige) 35674133_c3_298 5752 22323 489 162 21620718_c3_302 5753 22324 450 149 163 −11 Nephila AF027735 (de:nephila clavipes minor ampullate silk clavipes protein misp1 mrna, partialcds.) 36066393_c3_303 5754 22325 666 221 148 −8 Streptococcus CONTIG811 GTC ORF with score 248 to: (ai:279167) pneumoniae D (or:Caenorhabditis elegans) (sr:caenorhabditis elegans strain=bristol n2) (de:caenorhabditis elegans cosmid zk84.) (nt:final exon in repeat region; similar to long tandem) 25911066_c3_305 5755 22326 1068 355 150 −9 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 26041686_c3_307 5756 22327 1827 608 1265 −129 Klebsiella P15645 (de:(pullulanase secretion protein pule)) pneumoniae 20564083_c3_312 5757 22328 1185 394 1301 −133 Pseudomonas AF047381 (fn:cleaves esters of organic compounds and) aeruginosa (ec:3.1.3.1) (de:pseudomonas aeruginosa alkaline phosphatase (phoa) gene, completecds.) (nt:phosphomonoesterase; phosphodiesterase; low) 13130167_c3_313 5758 22329 588 195 36431706_c3_321 5759 22330 3390 1129 2054756_c3_322 5760 22331 639 212 102 −5 Klebsiella Contig553A GTC ORF with score 93 to: (ai:7000723189) pneumoniae (or:no gb taxonomy match) (de:human papillomavirus type 76 e6, e7, e1, e2, c4, l2, and l1 genes.) (nt:putative) 24867193_c3_330 5761 22332 192 63 13027093_c3_331 5762 22333 1761 586 168 −9 Erwinia L39897 (de:erwinia chrysanthemi phospholipase c chrysanthemi (plca) gene, partial cds; hrpf(hrpf), hrpg (hrpg), hrcc (hrcc), hrpt (hrpt), hrpv (hrpv), hrpnharpin (hrpn), orf1, and hecb (hecb) genes, complete cds and heca(heca) gene, partialcds.) (nt:simil . . . 16284832_c3_334 5763 22334 438 145 111 −5 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna,complete cds.) (nt:160 kda) 16102217_c3_336 5764 22335 900 299 195 −17 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 16260458_c3_337 5765 22336 408 135 131 −9 longfin squid S56117 (sr:, longfin squid) 22667750_f1_1 5766 22337 1287 428 640 −63 Escherichia B65048 coli 22916706_f1_10 5767 22338 1986 661 446 −40 Escherichia P52095 (cc:4.1.1.18) (de:lysine decarboxylase, coli constitutive, (ldc)) 16303878_f1_11 5768 22339 1539 512 32667261_f1_12 5769 22340 1233 410 234 −19 Klebsiella Contig516A GTC ORF with score 290 to: (ai:7000839846) pneumoniae (or:Enterobacter cloacae) 22692883_f1_13 5770 22341 2007 668 741 −73 Escherichia P41074 (de:glutamate/aspartate transport system coli permease protein gltj) 204456_f1_14 5771 22342 807 268 107 −6 Enterobacter CONTIG447 GTC ORF with score 135 to: (ai:7000769922) cloacae (or:Pseudomonas aeruginosa) 4401568_f1_15 5772 22343 1683 560 1102 −111 Escherichia P18956 (ec:2.3.2.2) (de:gamma-glutamyltranspeptidase coli precursor,) 31508316_f1_17 5773 22344 2748 915 748 −74 Rhizobium B33586 meliloti (megaplasmid pRME41B SYM) 16908442_f1_21 5774 22345 207 68 23851627_f1_22 5775 22346 1335 444 95 −2 Homo sapiens AJ223093 (sr:human) (de:homo sapiens lage-1gene.) 16023257_f1_23 5776 22347 300 99 26598333_f1_26 5777 22348 1554 517 1306 −133 Escherichia P76389 (de:hypothetical 59.5 kd protein in wza-asma coli intergenic region) 1461390_f1_29 5778 22349 1611 536 437 −41 Escherichia P75836 (de:hypothetical transcriptional regulator in coli dmsc-pfla intergenic region) 16928782_f1_30 5779 22350 2190 729 32697593_f1_34 5780 22351 516 171 149 −11 Klebsiella Contig545A GTC ORF with score 149 to: (ai:7000776261) pneumoniae (or:Pseudomonas aeruginosa) 26307181_f1_42 5781 22352 1071 356 485 −46 Enterobacter CONTIG430 GTC ORF with score 485 to: (ai:7000776269) cloacae (or:Pseudomonas aeruginosa) 34475693_f1_43 5782 22353 2115 704 108 −2 Human P09263 (sr:dumas,vzv) (de:alpha trans-inducing factor herpesvirus 3 91.8 kd protein) 6069541_f1_44 5783 22354 1995 664 384 −33 Klebsiella Contig546A GTC ORF with score 1232 to: pneumoniae (ai:7000826747) (or:Enterobacter cloacae) 21761031_f1_45 5784 22355 552 183 150 −10 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12239028_f1_47 5785 22356 426 141 97 −2 Caenorhabditis Z68297 (de:caenorhabditis elegans cosmid f11a10, elegans complete sequence.) (nt:cdna est embl:d32434 comes from this gene; cdna est) 35820391_f1_50 5786 22357 1383 460 153 −7 Caenorhabditis Z68108 (de:caenorhabditis elegans cosmid t05a10, elegans complete sequence.) (nt:similar to 11-s plant seed storage proteins, zinc) 14926967_f1_51 5787 22358 192 63 96 −5 Rattus X87883 (sr:norway rat) (de:r. norvegicus mrna for norvegicus mitochondrial capsule selenoprotein (846 bp).) 16213575_f1_52 5788 22359 789 262 106 −4 Klebsiella Contig516A GTC ORF with score 106 to: (ai:7000776279) pneumoniae (or:Pseudomonas aeruginosa) 3244056_f2_62 5789 22360 696 231 103 −3 Salmonella P26319 (de:fimbriae z protein) choleraesuis serotype typhimurium 32541590_f2_76 5790 22361 306 101 144 −9 Escherichia P37902 (de:region precursor) coli 35272752_f2_78 5791 22362 513 170 108 −6 Aspergillus Contig3629 GTC ORF with score 114 to: (ai:334261) fumigatus (or:Gossypium hirsutum) (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna. completecds.) 25584838_f2_79 5792 22363 1407 468 946 −95 Escherichia P41076 (de:glutamate/aspartate transport atp-binding coli protein gltl) 33797662_f2_81 5793 22364 1182 393 1526 −156 Pseudomonas AF056495 (ec:3.5.1.38) (de:pseudomonas fluorescens fluorescens glutaminase-asparaginase precursor, gene,complete cds.) (nt:periplasmatic) 29783158_f2_84 5794 22365 615 204 112 −7 Klebsiella Contig531A GTC ORF with score 134 to: (ai:7000766992) pneumoniae (or:Pseudomonas aeruginosa) 12604206_f2_85 5795 22366 879 292 135 −6 Caenorhabditis U80451 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid f11g11.) (nt:similar to collagen) 2519790_f2_86 5796 22367 1173 390 872 −87 Pseudomonas S64687 putida 29777281_f2_92 5797 22368 1338 445 22833530_f2_97 5798 22369 1488 495 496 −48 Enterobacter CONTIG471 GTC ORF with score 496 to: (ai:7000776324) cloacae (or:Pseudomonas aeruginosa) 11845843_f2_102 5799 22370 1440 479 136517_f2_113 5800 22371 216 71 31850831_f2_115 5801 22372 528 175 101 −4 Aspergillus Contig6651 GTC ORF with score 98 to: (ai:184549) fumigatus (or:Emericella nidulans) (sr:emericella nidulans (strain fgsc26) dna) (de:aspergillus nidulans regulatory protein (figa) gene, complete cds.) 31844030_f2_116 5802 22373 735 244 149 −10 Cyano- D64003 (sr:synechocystis sp. (strain:pcc6803) dna) synechocystis (de:synechocystis sp. pcc6803 complete genome, 22/27, 2755703-2868766.) (nt:orf id:slr0895) 26208330_f2_122 5803 22374 957 318 116 −4 Human P16818 (sr:ad169,) (de:hypothetical protein ul61) cytomegalo- virus 25423250_f3_124 5804 22375 1329 442 171 −9 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4) (de:ebna-1 virus nuclear protein) 17050318_f3_126 5805 22376 594 197 149 −9 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b putative type 6 HHV-6 major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 13020768_f3_129 5806 22377 1005 334 112 −5 Klebsiella Contig496A GTC ORF with score 100 to: (ai:394491) pneumoniae (or:Mus musculus) (sr:mouse dna, clones pmpc1c and pmpc1a) (de:mouse pro-alpha-1(i) procollagen gene.) 12369827_f3_133 5807 22378 954 317 126 −5 Burkholderia U97042 (de:burkholderia cepacia ceoa (ceoa) and ceob cepacia (ceob) genes, completecds.) (nt:similar to periplasmic link proteins) 2517881_f3_140 5808 22379 567 188 90 −2 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus glutamine 6xCBA/ repeat protein-1 mrna, complete cds.) (nt:grp- CaJ hybrid 1) 24901657_f3_142 5809 22380 762 253 155 −11 Klebsiella Contig489A GTC ORF with score 155 to: (ai:7000776369) pneumoniae (or:Pseudomonas aeruginosa) 603452_f3_143 5810 22381 669 222 548 −53 Escherichia P41075 (de:glutamate/aspartate transport system coli permease protein gltk) 16605427_f3_144 5811 22382 1722 573 122 −4 mice|C57BL/ S19560 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 16101058_f3_148 5812 22383 2391 796 1088 −110 Rhizobium P13632 (de:c4-dicarboxylate transport transcriptional meliloti regulatory protein dcdt) (megaplasmid pRME41B SYM) 2582906_f3_154 5813 22384 1275 424 132 −6 mice|C57BL/ C29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 5135143_f3_156 5814 22385 843 280 154 −8 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 34236687_f3_157 5815 22386 1041 346 113 −6 Klebsiella Contig492A GTC ORF with score 113 to: (ai:7000776384) pneumoniae (or:Pseudomonas aeruginosa) 34119443_f3_159 5816 22387 447 148 142 −9 Myxococcus AF055904 (de:myxococcus xanthus acetylornithine xanthus deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotpye) 7114075_f3_164 5817 22388 273 90 170 −13 Aspergillus Contig6057 GTC ORF with score 185 to: (ai:7000833564) fumigatus (or:Enterobacter cloacae) 33727031_f3_175 5818 22389 432 143 96 −5 longfin squid S56117 (sr:, longfin squid) 29567161_f3_179 5819 22390 1863 620 197 −12 Canadian hard S02262 (cl:glutenin) (sr:, common wheat) winter wheat 16893967_f3_183 5820 22391 747 248 187 −14 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 10737882_f3_184 5821 22392 1248 415 421 −39 Pseudomonas S77670 aeruginosa 5253256_c1_188 5822 22393 1416 471 479 −45 Propioni- D85417 (sr:propionibacterium freudenreichii bacterium (strain:ifo12424) dna) (de:propionibacterium freudenreichii freudenreichii hemy, hemh, hemb, hemx, hemr andheml genes, complete cds.) 21957588_c1_191 5823 22394 1476 491 159 −8 Nephila AF027972 (de:nephila clavipes flagelliform silk protein clavipes (flag) mrna, partialcds.) 5277043_c1_194 5824 22395 1005 334 918 −92 Escherichia P18400 (ec:1.10.3.—) (de:oxidase subunit 2)) coli 1213958_c1_195 5825 22396 1983 660 2524 −262 Escherichia P18401 (ec:1.10.3.—) (de:subunit 1)) coli 14931532_c1_196 5826 22397 633 210 751 −74 Escherichia P18402 (ec:1.10.3.—) (de:cytochrome o ubiquinol coli oxidase subunit iii,) 12352040_c1_197 5827 22398 915 304 1011 −102 Escherichia P18404 (de:cytochrome o ubiquinol oxidase operon coli protein cyoe) 12760006_c1_203 5828 22399 552 183 291 −26 Bacillus P37496 (de:hypothetical 14.6 kd protein in cotf-tetb subtilis/ intergenic region) Bacillus globigii 33719507_c1_207 5829 22400 1968 655 393 −34 Rhizobium sp. P55440 (sr:ngr234,) (de:hypothetical 73.7 kd protein y4fb) 25596961_c1_208 5830 22401 888 295 125 −6 Enterobacter CONTIG512 GTC ORF with score 532 to: (ai:7501734693) cloacae (or:Klebsiella pneumoniae) 2550042_c1_209 5831 22402 468 155 181 −14 Escherichia P45504 (de:glcg protein) coli 16902331_c1_210 5832 22403 213 70 103 −6 Klebsiella Contig470A GTC ORF with score 103 to: (ai:7000776437) pneumoniae (or:Pseudomonas aeruginosa) 33869717_c1_211 5833 22404 1074 357 309 −28 Klebsiella Contig544A GTC ORF with score 733 to: (ai:7000837893) pneumoniae (or:Enterobacter cloacae) 25573308_c1_212 5834 22405 768 255 422 −40 Klebsiella Contig544A GTC ORF with score 422 to: (ai:7000776439) pneumoniae (or:Pseudomonas aeruginosa) 24871007_c1_213 5835 22406 936 311 90 −1 Ovis orientalis U77049 (sr:sheep) (de:ovis aries bactinecin 11 (bac11) aries gene, exon 4, and complete cds.) 31883316_c1_219 5836 22407 2019 672 1025940l_c1_221 5837 22408 270 89 111 −7 Aspergillus Contig6518 GTC ORF with score 111 to: (ai:7000776448) fumigatus (or:Pseudomonas aeruginosa) 1197953_c1_223 5838 22409 2772 923 131 −7 Pyrococcus AP000001 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 1- 287000 nt. position (1/7).) 866392_c1_224 5839 22410 1077 358 317 −29 Klebsiella Contig489A GTC ORF with score 317 to: (ai:7000776451) pneumoniae (or:Pseudomonas aeruginosa) 14853152_c1_225 5840 22411 942 313 229 −19 Klebsiella Contig489A GTC ORF with score 234 to: (ai:7000811046) pneumoniae (or:Pseudomonas aeruginosa) 29737883_c1_228 5841 22412 855 284 642 −63 Bacillus E70027 (cl:ribitol dehydrogenase:short-chain alcohol subtilis/ dehydrogenase homology) Bacillus globigii 14974191_c1_229 5842 22413 330 109 3205035_c1_230 5843 22414 1314 437 359 −33 Archaeoglobus G69537 fulgidus 20183433_c1_231 5844 22415 1251 416 15751883_c1_236 5845 22416 498 165 154 −11 Rhizobium L39265 (sr:rhizobium meliloti (strain 1021) dna) meliloti (de:rhizobium meliloti 1021 ribosomal protein (megaplasmid s20 (rps20), enoyl coahydratase (fadb1), dnaa, pRME41B orfx, genes, complete cds, and SYM) orfy,formamidopyrimidine-dna glycosylase (fpg) genes. partial cds.) 16895843_c1_237 5846 22417 924 307 190 −15 Aspergillus Contig1117 GTC ORF with score 190 to: (ai:7000776464) fumigatus (or:Pseudomonas aeruginosa) 36603830_c1_239 5847 22418 1857 618 203 −12 Caenorhabditis Z68108 (de:caenorhabditis elegans cosmid t05a10, elegans complete sequence.) (nt:similar to 11-s plant seed storage proteins, zinc) 961393_c2_242 5848 22419 444 147 109 −6 Klebsiella Contig557A GTC ORF with score 190 to: (ai:7000834427) pneumoniae (or:Enterobacter cloacae) 5162918_c2_245 5849 22420 444 147 222 −19 Klebsiella Contig485A GTC ORF with score 296 to: (ai:7000842887) pneumoniae (or:Enterobacter cloacae) 35597826_c2_247 5850 22421 1599 532 670 −67 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 102/162.) (nt:rv2333c, (mtcy3g12.01), len: 537.similar to) 10257812_c2_256 5851 22422 1920 639 107 −2 Bos U35363 (sr:cow) (de:bos taurus latent tgf-beta binding primigenius protein-2 (ltbp-2) mrna,complete cds.) taurus 2812507_c2_258 5852 22423 393 130 128 −8 Escherichia P42617 (de:hypothetical 11.1 kd protein in exur-tdcc coli intergenic region) 34236580_c2_261 5853 22424 1842 613 310 −24 Micrococcus JQ0405 leteus 13145818_c2_268 5854 22425 1125 374 127 −5 Caenorhabditis Z75539 (de:caenorhabditis elegans cosmid f28c1, elegans complete sequence.) (nt:predicted using genefinder; cdna est embl:c13354) 12900028_c2_272 5855 22426 1311 436 96 −3 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 107/162.) (nt:rv2423, (mtcy428.24c), len: 348. unknown) 13019042_c2_276 5856 22427 1617 538 185 −13 Acromonas U56832 (de:aeromonas hydrophila fk506 binding hydrophila protein (fkpa) gene, completecds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 22671881_c2_284 5857 22428 471 156 217 −18 Klebsiella Contig549A GTC ORF with score 224 to: (ai:7000779823) pneumoniae (or:Pseudomonas aeruginosa) 21534466_c2_289 5858 22429 588 195 16902212_c2_291 5859 22430 195 64 91 −5 Klebsiella Contig516A GTC ORF with score 91 to: (ai:7000776518) pneumoniae (or:Pseudomonas aeruginosa) 34195452_c2_297 5860 22431 735 244 101 −2 Schizo- AF038575 (gn:wsp1+) (fn:actin patch assembly and saccharomyces localization) (sr:fission yeast) pombe (de:schizosaccharomyces pombe wiskott- aldrich syndrome protein homolog(wsp1+) gene, complete cds, and btf3/beta-nac gene, partialsequence.) (nt:wasp homolog: wsp . . . 14172580_c2_300 5861 22432 420 139 121 −6 equine D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus (de:equine herpesvirus 1 dna for membrane type 1 EVH-1 glycoprotein, complete cds.) 36600791_c2_301 5862 22433 1188 395 227 −16 Epstein-Barr P03181 (sr:b95-8,human herpesvirus 4) virus (de:hypothetical bhlf1 protein) 33707061_c2_303 5863 22434 435 144 107 −6 Aspergillus v1x1fj93.x GTC ORF with score 429 to: (ai:177837) fumigatus (or:Zea mays) (sr:, maize) 12970837_c3_308 5864 22435 1017 338 128 −5 Plasmodium A32068 (cl:circumsporozoite protein:thrombospondin vivax type 1 repeat homology) 26822705_c3_315 5865 22436 366 121 101 −5 herpes simplex M24771 (sr:herpes simples virus type 2 (strain 333) virus dna) (de:herpes simplex virus type 2 type 2 HSV-2 glycoprotein b (gb2) gene, completecds.) 31914558_c3_319 5866 22437 660 219 179 −14 Klebsiella Contig546A GTC ORF with score 179 to: (ai:7000776546) pneumoniae (or:Pseudomonas aeruginosa) 3382641_c2_321 5867 22438 1029 342 113 −6 Enterobacter CONTIG430 GTC ORF with score 113 to: (ai:70007765546) cloacae (or:Pseudomonas aeruginosa) 22448966_c3_322 5868 22439 888 295 357 −33 Escherichia U82664 (de:escherichia coli minutes 9 to 11 genomic coli sequence.) 14491275_c3_324 5869 22440 2226 741 3785 −9999 Pseudomonas AF051693 (de:pseudomonas aeruginosa hydroxamate- aeruginosa type ferrisiderophore receptor(pfua) gene, complete cds.) (nt:pfua) 10272837_c3_325 5870 22441 882 293 14151056_c3_327 5871 22442 2034 677 1564 −160 Cyano- S77559 (cl:threonine dehydratase) (sr:pcc 6803,,pcc bacterium 6803) (sr:pcc 6803,) (ec:4.2.1.16) synechocystis 32214203_c3_329 5872 22443 723 240 136 −8 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 123/162.) (nt:rv2839c, (mtcy16b7.03), len:900, probable infb.) 2523943_c3_331 5873 22444 534 177 109 −5 Klebsiella Contig549A GTC ORF with score 124 to: (ai:7000783409) pneumoniae (or:Pseudomonas aeruginosa) 22755382_c3_333 5874 22445 1236 411 302 −27 Bacillus C70023 subtilis/ Bacillus/ globigii 11055283_c3_337 5875 22446 633 210 118 −6 Klebsiella Contig553A GTC ORF with score 118 to: (ai:7000776564) pneumoniae (or:Pseudomonas aeruginosa) 35802081_c3_340 5876 22447 891 296 160 −12 Enterobacter CONTIG313 GTC ORF with score 160 to: (ai:7000776567) cloacae (or:Pseudomonas aeruginosa) 31908530_c3_348 5877 22448 1335 444 163 −10 Aspergillus Contig6518 GTC ORF with score 163 to: (ai:7000776575) fumigatus (or:Pseudomonas aeruginosa) 7210442_c3_350 5878 22449 891 296 111 −3 Mycobacterium AF027770 (de:mycobacterium smegmatis iron uptake smegmatis genes, fxba (fxba) gene,partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc(fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf)genes, complete cds.) (nt:similar to membrane b . . . 20974162_c3_355 5879 22450 1458 485 140 −5 Strongylo- S23809 (cl:collagen alpha 2(i) chain:fibrillar collagen centrotus carboxyl-terminal homology) (sr:, purple purpuratus urchin) 6152001_c3_365 5880 22451 1548 515 849 −85 Streptomyces AL031317 (de:streptomyces coelicolor cosmid 6g4.) coelicolor (nt:sc6g4.35, unknown, : 419 aa; similar to) 32703958_c3_366 5881 22452 777 258 221 −17 Myxococcus AF055904 (de:myxococcus xanthus acetylornithine xanthus deacetylase (arge) gene,complete cds; and unknown gene.) (nt:orf2; no developmental phenotype) 31644793_f1_1 5882 22453 1026 341 204 −16 Enterobacter CONTIG415 GTC ORF with score 204 to: (ai:7000776594) cloacae (or:Pseudomonas aeruginosa) 21746006_f1_7 5883 22454 951 316 490 −47 Escherichia P32064 (de:glycine cleavage system transcriptional coli activator) 33832205_f1_13 5884 22455 744 247 131 −5 Alphaherpes- B40505 virsus pseudorabies virus PRV 5324092_f1_14 5885 22456 558 185 278 −24 Archaeoglobus C69427 fulgidus 21648465_f1_16 5886 22457 822 273 10942208_f1_21 5887 22458 324 107 15105292_f1_22 5888 22459 813 270 286 −25 Enterobacter CONTIG340 GTC ORF with score 286 to: (ai:7000776615) cloacae (or:Pseudomonas aeruginosa) 26343966_f1_24 5889 22460 1254 417 114 −6 Klebsiella Contig529A GTC ORF with score 98 to: (ai:234137) pneumoniae (or:Escherichia coli) (fn:ribosome assembly; putative rna helicase) (de:escherichia coli jm101 dead protein (dead) gene, partial cds.) (nt:dead protein c-terminal sequence, aa 536- 646:) 16926582_f1_38 5890 22461 1707 568 109 −4 mice|C57BL/ D29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/ CaJ hybrid 26683290_f1_41 5891 22462 1545 514 1289216_f1_42 5892 22463 1209 402 116 −4 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 29556667_f1_49 5893 22464 1674 557 1233 −125 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:psfa; similar to glutathione-s transferase and) 36333287_f1_55 5894 22465 1674 557 288 −25 Schizo- U82218 (fn:putative acetyltransferase) (sr:fission yeast) saccharomyces (de:schizosaccharomyces pombe putative pombe acetyltransferase ats1 (ats1)mrna, complete cds.) 36034375_f1_59 5895 22466 864 287 564 −54 Brady- Y10223 (ec:3.1.1.24) (de:b. japonicum pcab, pcad & rhizobium pcac genes.) japonicum 31411425_f1_60 5896 22467 486 161 35652157_f1_66 5897 22468 582 194 448 −42 Pseudomonas Y11998 (de:p. fluorescens fc2.1, fc2.2, fc2.3c, fc2.4 fluorescens and fc2.5c open readingframes.) (nt:similar to e. coli gcvr (sp:p23483)) 34471930_f2_72 5898 22469 657 218 6367655_f2_73 5899 22470 243 80 110 −7 Klebsiella Contig378A GTC ORF with score 522 to: (ai:7000829899) pneumoniae (or:Enterobacter cloacae) 2939216_f2_74 5900 22471 1296 431 120 −4 Plasmodium M34697 (sr:p. vivax (strain thai; isolate nyu thai) vivax sporozoite dna) (de:p. vivax circumsporozoite protein gene, complete cds.) (nt:circumsporozoite protein) 30667257_f2_76 5901 22472 759 252 178 −12 Human P16818 (sr:ad169,) (de:hypothetical protein ul61) cytomegalo- virus 12526906_f2_77 5902 22473 675 224 493 −47 Rhizobium AF034831 (de:rhizobium etli stomatin like protein (slp) etli gene, complete cds.) (nt:orf2) 32538217_f2_78 5903 22474 546 181 553 −53 Rhizobium AF034831 (de:rhizobium etli stomatin like protein (slp) etli gene, complete cds.) (nt:slp) 26460775_f2_86 5904 22475 228 75 279 −24 Pseudomonas P95459 (de:major cold shock protein cspa) aeruginosa 16109816_f2_87 5905 22476 570 189 33707158_f2_89 5906 22477 813 270 263 −23 Klebsiella Contig544A GTC ORF with score 422 to: (ai:7000837913) pneumoniae (or:Enterobacter cloacae) 13072916_f2_90 5907 22478 2133 710 123 −4 no gb U93872 (sr:kaposi's sarcoma-associated herpesvirus - taxonomy human herpesvirus 8) (de:kaposi's sarcoma- match associated herpesvirus glycoprotein m, dnareplication protein, glycoprotein, dna replication protein, fliceinhibitory protein and y-cyclin genes . . . 14742628_f2_91 5908 22479 2469 822 219 −14 Micro- X79027 (de:m. ammoniaphilum genes mamir and bacterium mamim.) ammonia- philum 35783331_f2_92 5909 22480 1515 504 141 −9 Enterobacter CONTIG238 GTC ORF with score 141 to: (ai:7000776685) cloacae (or:Pseudomonas aeruginosa) 29505167_f2_94 5910 22481 2085 694 1122 −114 Escherichia S56623 (cl:envz protein:sensor histidine kinase coli homology) (ec:2.7.3.—) (mp:100 min) 14144793_f2_95 5911 22482 1461 486 747 −74 Escherichia P08369 (de:inner membrane protein cred) 32445463_f2_100 5912 22483 870 289 31930412_f2_108 5913 22484 420 139 4588168_f2_109 5914 22485 822 273 105 −3 Canis A45195 (cl:guanylate cyclase catalytic domain familiaris homology) (sr:, dog) 12586683_f2_111 5915 22486 1035 344 126 −4 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda-1102) virus ie2hom mrna, complete cds.) (nt:similar to the type 6/strain immediate-early 2 protein of human) Uganda-1102) 3206341_f3_131 5916 22487 1323 440 35447956_f3_133 5917 22488 855 284 102 −3 Caenorhabditis Z79694 (de:caenorhabditis elegans cosmid c15a11, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 16844502_f3_141 5918 22489 954 317 552 −53 Rhizobium AF034831 (de:rhizobium etli stomatin like protein (slp) etli gene, complete cds.) (nt:orf2) 22860427_f3_146 5919 22490 1932 643 244 −20 Klebsiella Contig390A GTC ORF with score 244 to: (ai:7000776739) pneumoniae (or:Pseudomonas aeruginosa) 13142150_f3_147 5920 22491 1620 539 491 −47 Klebsiella Contig560A GTC ORF with score 491 to: (ai:7000776740) pneumoniae (or:Pseudomonas aeruginosa) 5348957_f3_152 5921 22492 219 72 174 −13 Enterobacter CONTIG401 GTC ORF with score 174 to: (ai:7000776745) cloacae (or: Pseudomonas aeruginosa) 31330317_f3_154 5922 22493 3135 1044 2076 −215 Streptomyces AL023861 (de:streptomyces coelicolor cosmid 3c8.) coelicolor (nt:sc3c8.27c, clpa, probable clp protease atp binding) 24643791_f3_158 5923 22494 1068 355 16175708_f3_159 5924 22495 774 257 614 −60 Acromonas U67069 (fn:involved in the regulation of b-lactamase) jandaei (de:aeromonas jandaei response regulator protein (blra) gene, completecds and putative sensor kinase protein (blrb) gene, partial cds.) (nt:blra; part of a two component regulatory system) 33698783_f3_161 5925 22496 390 129 124 −7 Streptomyces P20186 (de:hypothetical 35.5 kd protein in transposon fradiae tn4556) 16057280_f3_163 5926 22497 603 200 180 −13 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29816656_f3_165 5927 22498 417 138 7052316_f3_173 5928 22499 801 266 105 −4 Klebsiella Contig529A GTC ORF with score 188 to: (ai:7000797120) pneumoniae (or:Pseudomonas aeruginosa) 15907265_f3_174 5929 22500 942 313 244 −21 Klebsiella Contig557A GTC ORF with score 91 to: (ai:7500975980) pneumoniae (or:Streptomyces coelicolor) (de:streptomyces coelicolor cosmid 1b5.) (nt:sc1b5.05c, unknown, : 438 aa; slight similarity) 16881941_f3_178 5930 22501 414 137 101 −4 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 24706957_f3_182 5931 22502 432 143 106 −4 Homo sapiens Z72496 (sr:human) (de:h. sapiens muc5b gene (partial).) 11152253_f3_183 5932 22503 585 194 229 −20 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 11/162.) (nt:rv0196, (mtv033.04), len: 194. possible regulatory) 30286651_f3_184 5933 22504 1473 490 450 −43 Klebsiella Contig551A GTC ORF with score 450 to: (ai:7000776777) pneumoniae (or:Pseudomonas aeruginosa) 36192681_f3_193 5934 22505 3036 1011 250 −20 Bacillus D69831 subtilis/ Bacillus globigii 31375792_c1_198 5935 22506 975 324 133 −6 Cellulomonas M94865 (sr:cellulomonas fimi (library: atcc 484) dna) fimi (de:cellulomonas fimi beta-glucosidase gene, complete cds.) 22914131_c1_199 5936 22507 1026 341 119 −5 mice|C57BL/ Q06666 (sr:,mouse) (de:octapeptide-repeat protein t2) 6xCBA/ CaJ hybrid 2991636_c1_202 5937 22508 924 307 221 −18 Achromobacter A61183 georgio- politanum 32692901_c1_203 5938 22509 1596 531 395 −37 Pseudomonas P10183 (de:transcriptional activator protein nahr) putida 10751283_c1_204 5939 22510 2295 764 91 −1 Paramecium U42580 (de:paramecium bursaria chlorella virus 1, bursaria complete genome.) (nt:papk (17x); similar to Chlorella pbcv-1 orf a41r, corresponds) virus 1 35650262_c1_207 5940 22511 1539 512 831 −83 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:fiui; regulatory component of two-component) 13007168_c1_210 5941 22512 2022 673 674 −66 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:fiua) 35785780_c1_213 5942 22513 1530 509 431 −40 Cyano- S76078 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803, ) bacterium synechocystis 36112530_c1_214 5943 22514 639 212 257 −22 Actinobacillus U89957 (de:actinobacillus pleuropneumoniae urease pleuro- operon (ureabcxefgd) genes,complete cds.) pneumoniae 16055455_c1_219 5944 22515 471 156 205 −17 Klebsiella Contig454A GTC ORF with score 205 to: (ai:7000776812) pneumoniae (or:Pseudomonas aeruginosa) 29930140_c1_234 5945 22516 474 157 353 −32 Acinetobacter CONTIG179 GTC ORF with score 105 to: (ai:4000712251) baumannii C (or:Synechocystis sp.) (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) 24488812_c1_237 5946 22517 1116 371 124 −4 Bos S18251 (cl:collagen alpha 1(v) chain:fibrillar collagen primigenius carboxyl-terminal homology) (sr:, cattle) taurus 22088407_c1_239 5947 22518 951 316 118 −4 Acanthamoeba P10569 (sr:,amoeba) (de:myosin ic heavy chain) castellanii 12755175_c1_240 5948 22519 2046 681 99 −2 Persian tobacco U45958 (sr:persian tobacco strain=breakthrough) (de:nicotiana alata pistil extensin-like protein mrna, complete cds.) 6141382_c1_248 5949 22520 1263 420 26308441_c1_251 5950 22521 660 219 97 −3 Aspergillus Contig4567 GTC ORF with score 97 to: (ai:7000776844) fumigatus (or:Pseudomonas aeruginosa) 31926041_c1_252 5951 22522 1305 434 1009 −102 Sphingomonas AF079317 (de:sphingomonas aromaticivorans plasmid aromatic- pnl1, complete plasmidsequence.) (nt:putative ivorans inner membrane protein similar to b.) 35804581_c1_253 5952 22523 762 254 437 −41 Rhizobium sp. P55615 (sr:ngr234,) (de:putative transposase y4pf/y4sb) 34430292_c2_257 5953 22524 2196 731 3267 −9999 Pseudomonas Y11998 (de:p. fluorescens fc2.1, fc2.2, fc2.3c, fc2.4 fluorescens and fc2.5c open readingframes.) (nt:most probably a malate synthase cds: insertion of a) 11110891_c2_259 5954 22525 591 196 111 −4 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 16824083_c2_260 5955 22526 1101 366 257 −22 Escherichia P42623 (de:hypothetical transcriptional regulator in coli exur-tdcc intergenic region) 4893777_c2_264 5956 22527 1809 602 791 −79 Bacillus P94575 (de:hypothetical 54.0 kd protein in nrga-usd subtilis/ intergenic region) Bacillus globigii 16022580_c2_269 5957 22528 1101 366 140 −7 Orf virus B34768 16928841_c2_271 5958 22529 1200 399 1986 −205 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:fiua) 22089153_c2_272 5959 22530 855 284 1470 −150 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:fiua) 16676686_c2_276 5960 22531 1020 339 256 −21 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 31353806_c2_278 5961 22532 1005 334 117 −3 herpes simplex Z86099 (fn:immediate early protein; transcriptional) virus (de:herpes simplex virus type 2 (strain hg52), type 2 HSV-2 complete genome.) 32711392_c2_282 5962 22533 492 163 122 −6 Alphaherpes- P33479 (sr:kaplan,prv) (de:immediate-early protein virus ie180) pseudorabies virus PRV 14711413_c2_284 5963 22534 621 206 110 −4 Rhizobium sp. S28675 11066715_c2_286 5964 22535 1200 399 35438503_c2_289 5965 22536 1578 525 325 −29 Aspergillus Contig10079 GTC ORF with score 325 to: (ai:7000776882) fumigatus (or:Pseudomonas aeruginosa) 10276087_c2_291 5966 22537 1605 534 236 −19 Klebsiella Contig544A GTC ORF with score 396 to: (ai:7000837986) pneumoniae (or:Enterobacter cloacae) 10597081_c2_294 5967 22538 1407 468 1249 −127 Escherichia P21693 (de:atp-dependent rna helicase dbpa) coli 12238161_c2_295 5968 22539 2214 737 1383 −141 Escherichia P75870 (de:hypothetical 82.0 kd protein in sula-held coli intergenic region) 16510183_c2_301 5969 22540 900 299 154 −8 Rhodothermus P49425 (cc:3.2.1.78) (de:mannan endo-1,4-beta- marinus mannosidase,) 16895913_c2_307 5970 22541 237 78 114 −6 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region) 4376013_c2_308 5971 22542 1242 413 1330 −136 Homo sapiens Q92947 (sr:,human) (ec:1.3.99.7) (de:glutaryl-coa dehydrogenase precursor,) 35650683_c3_315 5972 22543 510 169 121 −7 Homo sapiens U28835 (sr:human) (de:human gata-4 gene, partial cds.) (nt:similar to human gata-4 cdna sequence, genbank) 12194761_c3_319 5973 22544 510 169 102 −4 Klebsiella Contig417A GTC ORF with score 149 to: (ai:7000815725) pneumoniae (or:Enterobacter cloacae) 31891076_c3_320 5974 22545 360 119 95 −5 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 148/162.) (nt:protein sequence is in conflict with the conceptual) 33474158_c3_323 5975 22546 432 143 112 −5 Escherichia D90774 (sr:escherichia coli (strain:k12) dna, coli clone_lib:kohara lambda minise) (de:e. coli genomic dna, kohara clone #263(30.5-30.9 min.).) (nt:orf_id:o263#22; similar to (swissprot accession) 32313331_c3_328 5976 22547 1095 364 1609 −165 Pseudomonas AF051691 (de:pseudomonas aeruginosa stress factor a aeruginosa (psfa), ecf sigma factor(fiui), transmembrane sensor (fiur), and hydroxamate- typeferrisiderophore receptor (fiua) genes, complete cds.) (nt:fiur; transmembrane sensor component of) 11728788_c3_329 5977 22548 450 149 124 −8 Aspergillus Contig10074 GTC ORF with score 123 to: (ai:82733) fumigatus (or:Gallus gallus) (sr:gallus gallus (strain white leghorn, sub_species domesticus) (de:gallus gallus domesticus aortic lysyl oxidase mrna, complete cds.) 16055168_c3_335 5978 22549 1110 369 114 −3 Neisseria S75490 (sr:neisseria gonorrhoeae ms11) gonorrhoeae (de:competence region: iga=iga protease, coma=transformation competence(neisseria gonorrhoeae, ms11, genomic, 3 genes, 2664 nt).) 36145217_c3_336 5979 22550 2796 931 124 −4 Dictyostelium AJ224893 (fn:spore differentiation) (de:dictyostelium discoideum discoideum srfa gene.) 14345418_c3_337 5980 22551 1587 528 448 −42 Klebsiella Contig454A GTC ORF with score 448 to: (ai:7000776930) pneumoniae (or:Pseudomonas aeruginosa) 10056342_c3_340 5981 22552 1095 364 613 −60 Escherichia P32129 (de:hypothetical 36.3 kd protein in dsba-pola coli intergenic region) 16302281_c3_343 5982 22553 492 163 213 −18 Staphylococcus CONTIG068 GTC ORF with score 249 to: (ai:7000741630) epidermidis C (or:Enterococcus faecium) 33806941_c3_344 5983 22554 837 278 114 −4 Arabidopsis AC000098 (sr:thale cress) (de:arabidopsis thaliana thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts1136 comes from this gene.) 13946901_c3_348 5984 22555 1623 540 1161 −118 Escherichia P31474 (de:hypothetical 51.5 kd protein in rbsr-rrsc coli intergenic region) 9797542_c3_353 5985 22556 399 132 109 −6 bovine Z84818 (de:bovine herpesvirus type 4 gene encoding herpesvirus gp80.) type 4 BHV-4 10291455_c3_354 5986 22557 576 191 158 −10 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12161592_c3_357 5987 22558 648 215 105 −4 Enterobacter CONTIG362 GTC ORF with score 566 to: (ai:7501759493) cloacae (or:Klebsiella pneumoniae) 16538557_c3_358 5988 22559 723 240 245 −19 Rhodothermus X90947 (ec:3.2.1.78) (de:r. marinus mana gene.) marinus 13150630_c3_362 5989 22560 1794 597 964 −97 Escherichia P37308 (de:low-affinity inorganic phosphate coli transporter 1) 5343883_c3_365 5990 22561 324 107 92 −3 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16150655_c3_366 5991 22562 510 169 112 −4 Paramecium U42580 (de:paramecium bursaria chlorella virus 1, bursaria complete genome.) (nt:pro-, lys-rich, papk Chlorella (30x); similar to wheat pro-,) virus 1 11923251_c3_367 5992 22563 909 302 192 −12 Gallus gallus 150694 (cl:collagen alpha 1(i) chain:fibrillar collagen domesticus carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 14667557_f1_6 5993 22564 1290 429 217 −16 Enterobacter CONTIG487 GTC ORF with score 217 to: (ai:7000776967) cloacae (or:Pseudomonas aeruginosa) 16054702_f1_10 5994 22565 906 301 1005 −101 Escherichia P17116 (de:ribosomal protein s6 modification protein) coli 10269826_f1_13 5995 22566 948 315 111 −3 Homo sapiens U94836 (sr:human) (de:human erprot 213-21 mrna, complete cds.) 16926663_f1_14 5996 22567 639 212 374 −35 Klebsiella Contig468A GTC ORF with score 180 to: (ai: 161948) pneumoniae (or:Rhizobium sp.) (sr:rhizobium sp (strain ic 3342) (clone: pmnu4) (clone library: cosmi) (de:rhizobium sp. lcrabcde genes, complete cds's.) 29885156_f1_16 5997 22568 303 100 95 −4 Persian tobacco U88587 (sr:persian tobacco) (de:nicotiana alata 120 kda style glycoprotein (naprp5) mrna, completecds.) (nt:style-specific protein possessing features of) 16291455_f1_17 5998 22569 339 112 104 −5 Aspergillus Contig7774 GTC ORF with score 215 to: (ai:380588) fumigatus (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 11188532_f1_21 5999 22570 1374 457 963 −97 Escherichia A65049 (cl:glutamate-cysteine ligase) (ec:6.3.2.2) coli (mp:58 min) 30333268_f1_22 6000 22571 447 148 94 −4 Klebsiella Contig154A GTC ORF with score 94 to: (ai:7000776983) pneumoniae (or:Pseudomonas aeruginosa) 35831407_f1_25 6001 22572 1233 410 7213591_f1_26 6002 22573 654 217 287 −25 Klebsiella Contig441A GTC ORF with score 536 to: (ai:7000835893) pneumoniae (or:Enterobacter cloacae) 22049208_f1_28 6003 22574 783 260 92 −2 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus glutamine 6xCBA/ repeat protein-1 mrna, complete cds.) (nt:grp- CaJ hybrid 1) 11173582_f1_31 6004 22575 1494 497 342 −31 Escherichia P30871 (de:hypothetical 48.4 kd protein in glne-cca coli intergenic region (orfxc)) 3228758_f1_32 6005 22576 1146 381 148 −7 Homo sapiens S16506 (sr:, man) 2211018_f1_33 6006 22577 489 162 190 −14 Pseudomonas P24563 (de:hypothetical 57.4 kd protein in pilt region aeruginosa (orf4)) 12119816_f1_35 6007 22578 585 194 32525705_f1_37 6008 22579 3294 1097 1553 −160 Klebsiella Contig550A GTC ORF with score 2097 to: pneumoniae (ai:7000839066) (or:Enterobacter cloacae) 16877166_f1_39 6009 22580 1278 425 526 −51 Klebsiella Contig550A GTC ORF with score 966 to: (ai:7000817587) pneumoniae (or:Enterobacter cloacae) 22082336_f1_40 6010 22581 1371 456 146 −6 no gb taxonomy U93872 (sr:kaposi's sarcoma-associated herpesvirus - match human herpesvirus 8) (de:kaposi's sarcoma- associated herpesvirus glycoprotein m, dna replication protein, glycoprotein, dna replication protein, fliceinhibitory protein and v-cyclin genes. . . . 13023293_f1_47 6011 22582 567 188 125 −6 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 16831317_f1_50 6012 22583 1350 449 236 −19 Klebsiella Contig550A GTC ORF with score 236 to: pneumoniae (ai:7000777011) (or:Pseudomonas aeruginosa) 35367262_f1_56 6013 22584 354 117 32210826_f1_58 6014 22585 642 213 122 −5 Volvox carteri S22697 16495790_f1_60 6015 22586 738 245 572 −56 Klebsiella Contig556A GTC ORF with score 572 to: pneumoniae (ai:7000777021) (or:Pseudomonas aeruginosa) 4306908_f1_62 6016 22587 357 118 114 −7 Entamoeba Y14328 (de:entamoeba histolytica mrna for 3e1 histolytica protein.) 20175011_f1_72 6017 22588 1671 556 129 −4 Micrococcus JQ0405 luteus 22125442_f1_74 6018 22589 1662 553 779 −78 Enterobacter CONTIG437 GTC ORF with score 779 to: cloacae (ai:7000777035) (or:Pseudomonas aeruginosa) 25808261_f1_75 6019 22590 1425 474 14949031_f1_84 6020 22591 2328 775 220 −17 Klebsiella Contig521A GTC ORF with score 516 to: pneumoniae (ai:7000845660) (or:Enterobacter cloacae) 17036330_f1_86 6021 22592 1491 496 322 −29 Escherichia coli P27845 (de:hypothetical 17.1 kd protein in rard-plda intergenic region) 7066277_f1_95 6022 22593 765 254 102 −2 Saccharomyces X04289 (sr:baker's yeast) (de:yeast cell division cerevisiae control gene cdc39.) (nt:cdc39 gene product (aa 1-834)) 10831693_f1_101 6023 22594 1806 601 2903 −302 Pseudomonas JQ0135 aeruginosa 35675191_f1_103 6024 22595 648 215 976 −98 Pseudomonas JQ0142 aeruginosa 3410392_f1_115 6025 22596 708 235 147 −8 Dictyostelium P36417 (sr:,slime mold) (de:g-box binding factor discoideum (gbf)) 20183306_f1_127 6026 22597 651 216 169 −13 Klebsiella Contig470A GTC ORF with score 179 to: pneumoniae (ai:7000781592) (or:Pseudomonas aeruginosa) 22163265_f1_128 6027 22598 186 61 24422326_f1_129 6028 22599 1293 430 16665826_f1_130 6029 22600 642 213 379 −35 Escherichia coli AF044503 (de:escherichia coli strain cc11 unknown (498), hcp gene, complete cds;and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) 22855306_f1_131 6030 22601 1380 459 35255406_f1_133 6031 22602 720 239 131 −6 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 32672881_f1_134 6032 22603 1965 654 279 −24 Enterobacter CONTIG435 GTC ORF with score 662 to: cloacae (ai:7000758887) (or:Pseudomonas aeruginosa) 34417568_f1_135 6033 22604 2640 879 1444 −148 Cyanobacterium S76431 (cl:atp-dependent proteinase chain a) synechosystis (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) (ec:3.4.21.—) 16308293_f1_141 6034 22605 645 214 100 −2 Streptomyces AL022374 (de:streptomyces coelicolor cosmid 5b8). coelicolor (nt:sc5b8.06, unknown, len: 534 aa. contains probable) 36036375_f1_142 6035 22606 579 192 183 −14 Klebsiella Contig512A GTC ORF with score 760 to: pneumoniae (ai:7000817361) (or:Enterobacter cloacae) 16822941_f1_147 6036 22607 798 265 104 −2 Homo sapiens AF018082 (sr:human) (de:homo sapiens type xviii collagen (col18a1) mrna, alternatively splices, short form, complete cds.) (nt:alternatively spliced; short form (nc1-303)) 16254058_f1_151 6037 22608 378 125 115 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 15718890_f1_154 6038 22609 1152 383 348 −31 Streptomyces D31792 (sr:streptomyces griseus (strain:b2682) dna) griscus (de:streptomyces griseus dna for serine/threonine protein kinases, complete cds.) 9844792_f1_158 6039 22610 750 249 280 −24 Synechococcus U59236 (de:synechococcus pcc7942 ribosomal sp. (strain PCC protein s1 of 30s ribosome (rps1), orf271, 7942) orf231, orf341, carboxyltransferase alpha subunit (acca), orf2445, orf227, and gtp cyclohydrolase i (fole) genes, complete cds, and orf205 gene, partial cds) (nt . . . 14086006_f1_161 6040 22611 786 261 243 −20 Bordetella S66937 (de:orf1 . . . orf3 {transposon-like sequence} pertussis (bordetella pertussis, genomic, 3 genes, 2300 nt).) 32682183_f1_162 6041 22612 474 157 22767890_f1_170 6042 22613 1836 611 1489 −152 Schizosaccharo- AL031534 (sr:fission yeast) (de:s.pombe chromosome ii myces pombe cosmid c4f6.) (nt:spbc4f6.04c, :584) 24713206_f1_175 6043 22614 1377 458 215 −15 Volvox carteri S22697 26032056_f1_178 6044 22615 1695 564 462 −44 Klebsiella Contig448A GTC ORF with score 494 to: pneumoniae (ai:7000821045) (or:Enterobacter cloacae) 12712952_f1_181 6045 22616 1293 430 32620455_f1_186 6046 22617 702 233 108 −3 Homo sapiens P35527 (sr:,human) (de:keratin, type i cytoskeletal 9 (cytokeratin 9) (k9) (ck 9)) 26690891_f1_190 6047 22618 756 251 109 −3 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 14849163_f1_191 6048 22619 228 75 217 −18 Enterobacter CONTIG497 GTC ORF with score 103 to: (ai:183341) cloacae (or:Saccharomyces cerevisiae) (mp:151) 10353578_f1_192 6049 22620 414 137 444 −42 Klebsiella Contig445A GTC ORF with score 768 to: pneumoniae (ai:70000840406) (or:Enterobacter cloacae) 12502336_f1_195 6050 22621 765 254 161 −12 Enterobacter CONTIG497 GTC ORF with score 416 to: cloacae (ai:7501748785) (or:Klebsiella pneumoniae) 6891443_f1_199 6051 2262 879 292 207 −17 Klebsiella Contig437A TGC ORF with score 207 to: pneumoniae (ai:7000777160) (or:Pseudomonas aeruginosa) 11720382_f1_200 6052 22623 777 258 122 −4 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 3175844a_f1_201 6053 22624 792 263 186 −25 Klebsiella Contig324A GTC ORF with score 448 to: pneumoniae (ai:7000827288) (or:Enterobacter cloacae) 16304206_f1_202 6054 22625 984 327 397 −37 Klebsiella Contig546A GTC ORF with score 492 to: pneumoniae (ai:7000835591) (or:Enterobacter cloacae) 10942916_f1_207 6055 22626 615 204 343 −31 Enterobacter CONTIG480 GTC ORF with score 343 to: cloacae (ai:7000777168) (or:Pseudomonas aeruginosa) 10979702_f1_208 6056 22627 897 298 380 −35 Enterobacter CONTIG480 GTC ORF with score 766 to: cloacae (ai:7501786773) (or:Klebsiella pneumoniae) 2520376_f1_213 6057 22628 864 287 137 −9 Klebsiella Contig398A GTC ORF with score 137 to: pneumoniae (ai:7000777174) (or:Pseudomonas aeruginosa) 16526031_f1_214 6058 22629 339 112 101 −5 Orf virus D34768 14149081_f1_218 6059 22630 438 145 106 −4 Homo sapiens Y10351 (sr:human) (de:h.sapiens mrna for nuclear protein sdk3, partial.) 12975955_f1_222 6060 22631 804 267 742 −73 Pseudomonas AF054622 (de:pseudomonas aeruginosa phpa (phpa) aeruginosa and dna polymerase holoenzzymechi subunit (holc) genes, complete cds.) (nt:holc; similar to escherichia coli holc) 14957283_f1_224 6061 22632 195 64 135 −9 Enterobacter CONTIG446 GTC ORF with score 367 to: cloacae (ai:7501741072) (or:Klebsiella pneumoniae) 35425956_f1_226 6062 22633 423 140 158 −11 Homo sapiens Z34278 (sr:human) (de:h.sapiens (jer58) muc5ac mrna for mucin (partial).) 34239665_f1_227 6063 22634 468 155 185 −13 Saccharomyces P08640 (sr:baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 12234827_f1_233 6064 22635 1008 335 146 −6 Homo sapiens M94173 (fn:calcium influx) (sr:homo sapiens cns cdna to mrna) (de:human n-type calcium channel alpha-1 subunit mrna, complete cds.) (nt:putative) 21505030_f1_234 6065 22636 921 306 365 −35 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 33708165_f1_236 6066 22637 2085 694 1897 −196 Escherichia coli P77741 (de:hypothetical 65.9 kd protein in Irha-acka intergenic region) 1425082_f1_239 6067 22638 1476 491 16661306_f1_241 6068 22639 1164 387 291 −26 Pseudomonas L27629 (sr:pseudomonas aeruginosa (strain 388) aeruginosa dna) (de:pseudomonas aeruginosa exoenzyme s (exos) gene, complete cds.) (nt:orf3) 16145925_f1_242 6069 22640 999 332 416 −39 Escherichia coli P77741 (de:glycine cleavage system transcriptional activator) 34270755_f1_243 6070 22641 627 208 129 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 12369193_f1_244 6071 22642 1413 470 16831333_f1_249 6072 22643 987 328 103 −2 Boreogadus saida U43200 (de:boreogadus saida antifreez glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16181961_f2_263 6073 22644 846 281 191 −15 Escherichia coli P76445 (de:hypothetical 26.8 kd protein in frub-spr intergenic region) 13020942_f2_265 6074 22645 705 234 16144667_f2_267 6075 22646 1014 337 300 −26 Cyanobacterium S75855 (sr:pcc 6803, pcc 6803) (sr:pcc 6803,) synechocystis 32317883_f2_271 6076 22647 642 213 107 −4 Pseudomonas X80272 (de:p. putida pprb gene.) putida 24422908_f2_275 6077 22648 807 268 185 −15 Klebsiella Contig373A GTC ORF with score 185 to: pneumoniae (ai:7000777236) (or:Pseudomonas aeruginosa) 35805381_f2_276 6078 22649 1284 427 154 −10 Sulfolobus S74052 solfataricus 32703842_f2_280 6079 22650 384 127 111 −6 Acinetobacter CONTIG162 GTC ORF with score 887 to: baumannii C (ai:7000688911) (or:Escherichia coli) (ec:6.3.2.2) (de: escherichia coli k-12 mg1655 section 243 of 400 of the completegenome.) (nt:f518; 99 pct identical to gsh1 ecoli sw: p06980 cg) 16175206_f2_281 6080 22651 1209 402 299 −27 Enterobacter CONTIG441 GTC ORF with score 299 to: cloacae (ai:7000777242) (or:Pseudomonas aeruginosa) 1254133_f2_282 6081 22652 756 251 554 −53 Salmonella Q56068 (de:hypothetical 23.6 kd protein in marr choleraesuis 5′region (orf221)) serotype typhimurium 14087830_f2_284 6082 22653 627 208 124 −8 Enterobacter CONTIG481 GTC ORF with score 124 to: cloacae (ai:700777245) (or:Pseudomonas aeruginosa) 33863576_f2_285 6083 22654 585 194 128 −8 Pyrococcus AP000003 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 544001-777000 nt. position(3/7).) 14969540_f2_289 6084 22655 423 140 103 −4 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 31276512_f2_291 6085 22656 1827 608 912 −91 Aquifex B70469 aeolicus 22112643_f2_295 6086 22657 225 74 203 −17 Klebsiella Contig550A GTC ORF with score 203 to: pneumoniae (ai:7000777256) (or:Pseudomonas aeruginosa) 36422257_f2_313 6087 22658 1449 482 16931443_f2_314 6088 22659 1311 436 165 −12 Enterobacter CONTIG320 GTC ORF with score 263 to: cloacae (ai:7501790323) (or:Klebsiella pneumoniae) 36431308_f2_318 6089 22660 1494 497 392 −37 Enterobacter CONTIG320 GTC ORF with score 514 to: cloacae (ai:7501793024) (or:Klebsiella pneumoniae) 34610212_f2_320 6090 22661 396 131 99 −5 Homo sapiens A60533 (sr:, man) (mp:1q21-q24) 35817281_f2_321 6091 22662 552 183 95 −3 Escherichia P09160 (de:hypothetical 21.1 kd protein in ssr-sera coli intergenic region (o182)) 4351633_f2_323 6092 22663 696 231 106 −3 Aspergillus Contig8665 GTC ORF with score 154 to: fumigatus (ai:7501004138) (or:Mus musculus) (sr:house mouse) (de:mus musculus plenty-of-prolines-101 mrna, complete cds.) (nt:binds to several sh3 domain containing proteins) 12589442_f2_326 6093 22664 420 139 122 −7 Canorhabditis Z70208 (de:caenorhabditis elegans cosmid f54b11, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen) 31369582_f2_327 6094 22665 651 216 114 −4 Orf virus D34768 12595766_f2_328 6095 22666 1263 420 465 −44 Klebsiella Contig556A GTC ORF with score 465 to: pneumoniae (ai:7000777289) (or:Pseudomonas aeruginosa ) 1177282_f2_330 6096 22667 1239 412 565 −55 Mycobacterium Z92770 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 8/162.)(nt:rv0149, (mtci5.23), len: 322 aa, putative) 14974187_f2_332 6097 22668 1380 459 1795 −185 Escherichia P08194 (de:permease)) coli 25808418_f2_340 6098 22669 1506 501 638 −63 Enterobacter CONTIG359 GTC ORF with score 649 to: cloacae (ai:7501750649) (or:Klebsiella pneumoniae) 25432025_f2_342 6099 22670 1671 556 16073401_f2_349 6100 22671 768 255 120 −6 Aspergillus Contig8218 GTC ORF with score 100 to: (ai:186949) fumigatus (or:Loligo pealei) (sr:, longfin squid) 12394807_f2_250 6101 22672 813 270 700 −69 Escherichia P26428 (de:sigma cross-reacting protein 27a (scrp- coli 27a)) 10352215_f2_356 6102 22673 561 186 171 −12 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 33854161_f2_359 6103 22674 930 309 163 −12 Klebsiella Contig534A GTC ORF with score 480 to: pneumoniae (ai:7000828725) (or:Enterbacter cloacae) 32597082_f2_363 6104 22675 831 276 1193 −121 Pseudomonas JQ0133 aeruginosa 14876918_f2_364 6105 22676 486 161 825 −82 Pseudomonas JQ0136 aeruginosa 7057338_f2_365 6106 22677 756 251 875 −87 Pseudomonas JQ0138 aeruginosa 10995803_f2_366 6107 22678 612 203 850 −85 Pseudomonas JQ0139 aeruginosa 32673341_f2_367 6108 22679 573 190 838 −83 Pseudomonas JQ0141 aeruginosa 33619552_f2_368 6109 22680 438 145 580 −56 Pseudomonas JQ0143 aeruginosa 16824216_f2_370 6110 22681 399 132 93 −3 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine-and) 12238306_f2_373 6111 22682 1374 457 14978790_f2_378 6112 22683 2052 683 166 −8 Homo sapiens AF048977 (fn:splicing factor)(sr:human)(de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrma,complete cds.)(nt:160 kda) 36114058_f2_380 6113 22684 198 65 35291681_f2_387 6114 22685 411 136 97 −3 Caenorhabditis U41538 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid r04c5.) (nt:proline rich; coded for by c. elegans cdna) 5344217_f2_392 6115 22686 1566 521 139 −6 Acinetobacter CONTIG214 GTC ORF with score 346 to: baumannii C (ai:7000787380) (or:Pseudomonas aeruginosa) 12213333_f2_393 6116 22687 1530 509 1021 −103 Edwardsiella AF037441 (de:edwardsiella ictaluri putative 18.8 kda icaluri protein (eip19), putative 17.8 kda protein (cip18), putative 54.5 kda protein (eip55), and putative 19.5 kda protein (eip20) genes, complete cds.)(nt:eip55; antigenic to catfish) 9792333_f2_394 6117 22688 420 139 120 −8 Klebsiella Contig512A GTC ORF with score 634 to: pneumoniae (ai:7000817372) (or:Enterobacter cloacae) 478533_f2_396 6118 22689 1791 596 730 −72 Klebsiella Contig512A GTC ORF with score 730 to: pneumoniae (ai:7000777357) (or:Pseudomonas aeruginosa) 30720955_f2_398 6119 22690 408 135 134 −8 Schizosacchar- Z95620 (sr:fission yeast)(de:s.pombe chromosome ii omyces cosmid c3d6.)(nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 6488191_f2_401 6120 22691 597 198 119 −4 Homosapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s)(de:homo sapiens mrna for kiaa0595 protein, partial cds.) 29800955_f2_402 6121 22692 1659 552 685 −67 Escherichia coli P14375 (de:transcriptional regulatory protein hydg) 11727205_f2_403 6122 22693 1431 476 191 −12 Enterobacter CONTIG435 GTC ORF with score 103 to: cloacae (ai:286797) (or:Entamoeba histolytica)(sr:entamoeba histolytica (strain saw142)(library: lambda zap) cdna t)(de:entamoeba histolytica k2 mrna. 3′ end. 1992257_f2_407 6123 22694 900 299 446 −42 Enterobacter CONTIG436 GTC ORF with score 216 to: cloacae (ai:4000713594) (or:Vibrio alginolyticus)(sr:vibrio alginolyticus (strain:vi05) dna)(de:vibrio alginolyticus dna for poma, pomb, complete cds.)(nt:essential for rotation of the sodium- driven polar) 32323307_f2_408 6124 22695 1506 501 589 −56 Enterobacter CONTIG436 GTC ORF with score 1002 to: cloacae (ai:7000758857) (or:Pseudomonas aeruginosa) 15907891_f2_413 6125 22696 852 283 336 −30 Mycobacterium Z70722 (de:mycobacterium leprae cosmid b1770.) leprae (nt:mlb1770.13c, ppp; putative phosphoprotein) 34183557_f2_419 6126 22697 432 143 104 −4 Brucella abortus AF070932 (de:brucella abortus 2-oxoglutaric dehydrogenase operon, partialsequence.) 12977308_f2_425 6127 22698 453 150 129 −8 Homo sapiens S16506 (sr:, man) 34636401_f2_439 6128 22699 483 160 122 −7 Microbacterium X79027 (de:m. ammoniaphilum genes mamir and ammoniaphilum mamin.) 31753457_f2_445 6129 2270 522 173 220 −18 Klebsiella Contig448A GTC ORF with score 220 to: pneumoniae (ai:7000777406) (or:Pseudomonas aeruginosa) 29792703_f2_446 6130 22701 519 172 145 −10 Klebsiella Contig448A GTC ORF with score 220 to: pneumoniae (ai:7000777406) (or:Pseudomonas aeruginosa) 35681967_f2_454 6131 22702 2202 733 532 −51 Klebsiella Contig448A GTC ORF with score 802 to: pneumoniae (ai:7000840426) (or:Enterobacter cloacae) 17035326_f2_453 6132 22703 579 192 132 −6 Epstein-Barr P03211 (sr:b95-8,human herpesvirus 4)(de:ebna-1 virus nuclear protein) 7164216_f2_455 6133 22704 1764 587 583 −57 Klebsiella Contig213A GTC ORF with score 753 to: pneumoniae (ai:7000840371) (or:Enterobacter cloacae) 3328293_f2_456 6134 22705 654 217 256 −22 Klebsiella Contig445A GTC ORF with score 405 to: pneumoniae (ai:7000840373) (or:Enterobacter cloacae) 1307183_f2_468 6135 22706 564 187 285 −25 Enterobacter CONTIG497 GTC ORF with score 285 to: cloacae (ai:7000777429) (or:Pseudomonas aeruginosa) 16148461_f2_469 6136 22707 819 272 158 −10 Klebsiella Contig555A GTC ORF with score 383 to: (ai:67716) pneumoniae (or:Escherichia coli)(sr:e.coli (strain k-12) dna)(de:e.coli cysteine regulon 33 kd (cyse) and 16 kd protein (cysx)genes, complete cds.) (nt:16 kd protein (cysx)) 14853576_f2_471 6137 22708 1005 334 744 −74 Escherichia P22783 (de:extragenic suppressor protein suhb) coli 25910388_f2_477 6138 22709 870 289 338 −31 Klebsiella Contig546A GTC ORF with score 407 to: (ai:163251) pneumoniae (or:Escherichia coli) 2239753_f2_478 6139 22710 606 201 146 −9 Klebsiella Contig546A GTC ORF with score 407 to: ai:163251) pneumoniae (or:Escherichia coli) 29941430_f2_480 6140 22711 483 160 103 −4 Drosophila P50887 (sr:,fruit fly)(de:60s ribosomal protein 122) melanogaster 10287706_f2_484 6141 22712 825 274 201 −15 Enterobacter CONTIG261 GTC ORF with score 554 to: cloacae (ai:7501745490) (or:Klebsiella pneumoniae) 15714825_f2_486 6142 22713 609 202 125 −6 Mycobacterium Z97050 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 10/162.) (nt:rv0176, (mtci28.16), unknown, len: 322 aa;) 12322280_f2_489 6143 22714 1053 350 167 −10 Klebsiella Contig398A GTC ORF with score 527 to: pneumoniae (ai:7000813455) (or:Enterobacter cloacae) 13002087_f2_495 6144 22715 1473 490 425 −40 Pseudomonas AF054622 (de:pseudomonas aeruginosa phpa (phpa) and aeruginosa dna polymerase holoenzymechi subunit (holc) genes, complete cds.)(nt:alternative putative start codon indicated at nt) 25836631_f2_498 6145 22716 918 305 153 −11 Enterobacter CONTIG446 GTC ORF with score 307 to: cloacae (ai:7501741046) (or:Klebsiella pneumoniae) 36345128_f2_501 6146 22717 861 286 145 −8 mice S50883 (sr:mice macrophage)(de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 33256517_f2_504 6147 22718 294 97 31297506_f2_506 6148 22719 1194 397 168 −11 Rickettsia AJ234269 Rickettsia prowazekki strain Madrid E, prowazekii complete genome. 29817192_f2_508 6149 22720 951 316 131 −6 mice|C57BL/ A24264 (cl:proline-rich protein)(sr:, house mouse) 6xCBA/ CaJ hybrid 29970775_f2_509 6150 22721 1125 374 877 −88 Escherichia P75782 (de:hypothetical 37.3 kd protein in ding-glnq coli intergenic region) 31656961_f2_513 6151 22722 408 135 611 −59 Pseudomonas L27629 (sr:pseudomonas aeruginosa (strain 388) dna) aeruginosa (de:pseudomonas aeruginosa exoenzyme s (exos) gene, complete cds.)(nt:orf1) 12355042_f2_518 6152 22723 582 193 152 −9 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda-1102) virus (type ie2hom mrna, complete cds.)(nt:similar to the 6/strain immediate-early 2 protein of human) Uganda-1102) 32055436_f2_521 6153 22724 750 249 144 −7 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology)(sr:, african clawed frog) 22442282_f2_526 6154 22725 1455 484 39813_f3_529 6155 22726 477 158 4400641_f3_530 6156 22727 1707 568 437 −41 Klebsiella Contig557A GTC ORF with score 884 to: pneumoniae (ai:7000837516) (or:Enterobacter cloacae) 36539558_f3_540 6157 22728 798 265 189 −14 Klebsiella Contig560A GTC ORF with score 189 to: pneumoniae (ai:7000777501) (or:Pseudomonas aeruginosa) 130415_f3_543 6158 22729 2406 801 2428 −252 Escherichia P46837 (de:hypothetical 81.4 kd protein in greb-feoa coli intergenic region) 16589566_f3_545 6159 22730 1221 406 29588507_f3_554 6160 22731 510 169 120 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s)(de:human mrna for kiaa0324 gene, partial cds.) 14923782_f3_559 6161 22732 1173 390 114 −3 Alvinella AF053538 (de:alvinella pompejana fibrillar collagen pompejana chain fap1 alpha mrna,partial cds.)(nt:includes half of the collagenous domain (171 g-x-y)) 16227066_f3_560 6162 22733 768 255 164 −10 Boreogadus U43200 (de:boreogadus saida antifreeze glycopeptide saida afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 24886403_f3_561 6163 22734 411 136 150 −9 Saccharomyces P32323 (sr:,baker's yeast)(de:a-agglutinin attachment cerevisiae subunit precursor) 22770265_f3_565 6164 22735 363 120 10937966_f3_571 6165 22736 603 200 225 −18 Klebsiella Contig550A GTC ORF with score 966 to: pneumoniae (ai:7000817587) (or:Enterobacter cloacae) 16886041_f3_575 6166 22737 408 135 113 −7 Klebsiella Contig242A GTC ORF with score 345 to: pneumoniae (ai:7000827067) (or:Enterobacter cloacae) 5117683_f3_579 6167 22738 945 314 108 −4 Klebsiella Contig549A GTC ORF with score 108 to: pneumoniae (ai:7000777540) (or:Pseudomonas aeruginosa) 15807903_f3_580 6168 22739 1299 432 399 −37 Bacillus P37498 (de:hypothetical 44.2 kd protein in cotf-tetb subtilis/Bacillus intergenic region) globigii 35629168_f3_587 6169 22740 933 310 103 −3 Chlamydomonas S19114 reinhardtii strain UTEX 1061 31830408_f3_589 6170 22741 420 139 92 −2 Caenorhabditis U41557 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid e50f7.) (nt:proline and glycine-rich) 12972280_f3_592 6171 22742 423 140 98 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 21675700_f3_593 6172 22743 555 184 133 −9 Escherichia coli P45580 (de:hypothetical 12.6 kd protein in pepp-ssr intergenic region (o109)) 24079705_f3_595 6173 22744 609 202 240 −20 Escherichia coli P09160 (de:hypothetical 21.1 kd protein in ssr-sera intergenic region (o182)) 916562_f3_596 6174 22745 564 187 376 −35 Cyanobacterium S75679 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 10407667_f3_597 6175 22746 3948 1315 128 −4 Oryctolagus P16230 (sr:,rabbit) (de:precursor (hep)) cuniculus 33728832_f3_598 6176 22747 972 323 126 −5 equine D88734 (sr:equine herpesvirus 1 (strain:bk343, herpesvirus isolate:3f clone) dna) (de:equine herpesvirus type 1 EVH-1 1 dna for membrane glycoprotein, complete cds.) 36066632_f3_605 6177 22748 249 82 192 −15 Klebsiella Contig534A GTC ORF with score 192 to: pneumoniae (ai:7000777566) (or:Pseudomonas aeruginosa) 29375833_f3_610 6178 22749 822 273 164 −10 Klebsiella Contig559A GTC ORF with score 250 to: pneumoniae (ai:15000692508) (or:Boreogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 6838537_f3_615 6179 22750 1674 557 1010 −102 Vibrio cholerae AF083928 (de:vibrio cholerae polyphosphate kinase (ppk) and exopolyphosphatase(ppx) genes, complete cds.) 35784450_f3_618 6180 22751 1167 388 283 −25 Klebsiella Contig520A GTC ORF with score 920 to: pneumoniae (ai:7000833072) (or:Enterobacter cloacae) 10026008_f3_619 6181 22752 621 206 317 −28 Escherichia coli G64981 12114777_f3_622 6182 22753 2499 832 24348881_f3_624 6183 22754 1137 378 326 −30 Klebsiella Contig544A GTC ORF with score 422 to: pneumoniae (ai:7000776439) (or:Pseudomonas aeruginosa) 26069586_f3_626 6184 22755 444 147 100 −4 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin domesticus gene coding for phosvitin, exons 23 and 24.) 10822580_f3_627 6185 22756 579 192 110 −7 Klebsiella Contig543A GTC ORF with score 110 to: pneumoniae (ai:7000777588) (or:Pseudomonas aeruginosa) 24878967_f3_631 6186 22757 912 303 1346 −137 Pseudomonas JQ0137 aeruginosa 12614532_f3_633 6187 22758 717 238 1142 −116 Pseudomonas P30417 (ec:5.2.1.8) (de:(ec 5.2.1.8) (ppiase) aeruginosa (rotamase)) 33852090_f3_636 6188 22759 1671 556 12600806_f3_640 6189 22760 1998 665 26291308_f3_643 6190 22761 1623 540 1202 −122 Cyanobacterium S77437 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis (ec:4.3.2.1) 16897931_f3_649 6191 22762 1269 422 15741681_f3_650 6192 22763 1503 500 117 −5 Enterobacter CONTIG211 GTC ORF with score 224 to: cloacae (ai:7000807782) (or:Pseudomonas aeruginosa) 23569467_f3_658 6193 22764 198 65 29557908_f3_665 6194 22765 693 230 201 −14 Rattus norvegicus Z78279 (sr:norway rat) (de:r. norvegicus mrna for collagen alpha1 type i.) (nt:type i) 36453941_f3_666 6195 22766 1053 350 121 −4 Caenorhabditis U12966 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid f54d8.) (nt:similar to triple helical region of collagens;) 4142783_f3_667 6196 22767 249 82 103 −5 mice|C57BL/ A38346 (sr:, house mouse) 6xCBA/CAJ hybrid 11210430_f3_669 6197 22768 621 206 150 −11 Enterobacter CONTIG344 GTC ORF with score 299 to: cloacae (ai:7501741357) (or:Klebsiella pneumoniae) 24651041_f3_676 6198 22769 1338 445 265 −22 Vibrio cholerae AJ231091 (de:vibrio cholerae z29f gene.) 34472505_f3_678 6199 22770 2256 751 339 −27 Legionella Y15044 (de:legionella pneumophila 22kb dna pneumophila fragment from icm gene cluster.) 12359816_f3_681 6200 22771 765 254 121 −5 Pseudomonas S29309 aeruginosa 4776081_f3_683 6201 22772 552 183 205 −15 Desulfovibrio U30319 (fn:chemoreceptor) (de:desulfovibrio vulgaris vulgaris chemoreceptor dcrh (dcrh) gene, complete cds.) (nt:similar to the class of methyl- accepting chemotaxis) 7268328_f3_686 6202 22773 918 305 327 −29 Synechococcus D13173 (sr:synechococcus elongatus dna) elongatus (de:synechococcus elongatus phycocyanin genes.) 15058431_f3_687 6203 22774 1272 423 110 −3 Dictyostelium AJ224893 (fn:spore differentiation) (de:dictyostelium discoideum discoideum srfa gene.) 21689586_f3_697 6204 22775 777 258 108 −4 Acinetobacter CONTIG180 GTC ORF with score 159 to: (ai:195953) baumannii C (or:Homo sapiens) (sr:, man) 14181541_f3_702 6205 22776 954 317 432 −40 Agrobacterium U19620 (de:agrobacterium tumefaciens plasmid tumefaciens (TI pti15955 moc operon, kinase(moce), PLASMID conjugase (mocd), repressor (mocr), PTIBO542) mannopine oxidase(mocc), dehydratase (mocb), oxido-reductase (moca), and repressor(mocr′) genes, complete cds, and mannoninc cyc. . . . 21896033_f3_704 6206 22777 312 103 29940626_f3_707 6207 22778 1197 398 289 −26 Klebsiella Contig554A GTC ORF with score 363 to: pneumoniae (ai:7000841963) (or:Enterobacter cloacae) 16917641_f3_712 6208 22779 1215 404 159 −10 Klebsiella Contig448A GTC ORF with score 159 to: pneumoniae (ai:7000777673) (or:Pseudomonas aeruginosa) 13064832_f3_716 6209 22780 543 180 407 −38 Klebsiella Contig448A GTC ORF with score 407 to: pneumoniae (ai:7000777677) (or:Pseudomonas aeruginosa) 10665705_f3_721 6210 22781 258 85 157 −12 Klebsiella Contig213A GTC ORF with score 251 to: pneumoniae (ai:7000777683) (or:Pseudomonas aeruginosa) 11027206_f3_722 6211 22782 456 151 251 −22 Klebsiella Contig213A GTC ORF with score 251 to: pneumoniae (ai:7000777683) (or:Pseudomonas aeruginosa) 35586456_f3_727 6212 22783 2112 703 507 −48 Drosophila X78403 (de:d.auraria mrna for hsp70.) auraria 20171881_f3_729 6213 22784 1599 532 749 −74 Klebsiella Contig437A GTC ORF with score 1104 to: pneumoniae (ai:7000840410) (or:Enterobacter cloacae) 13088183_f3_730 6214 22785 267 88 116 −7 Enterococcus CONTIG046 GTC ORF with score 199 to: faecium C (ai:4500688524) (or:Enterococcus faecalis) 12782058_f3_732 6215 22786 429 142 186 −15 Enterobacter CONTIG497 GTC ORF with score 299 to: cloacae (ai:7501747262) (or:Klebsiella pneumoniae) 35678818_f3_734 6216 22787 330 109 124 −8 Orf virus C34768 660777_f3_739 6217 22788 429 142 107 −6 Staphylococcus CONTIG067 GTC ORF with score 108 to: epidermidis C (ai:7000777700) (or:Pseudomonas aeruginosa) 24034668_f3_743 6218 22789 1536 511 383 −36 Enterobacter CONTIG480 GTC ORF with score 583 to: cloacae (ai:7501786772) (or:Klebsiella pneumoniae) 12994091_f3_756 6219 22790 1512 503 2010 −208 Pseudomonas AF054622 (de:pseudomonas aeruginosa phpa (phpa) aeruginosa and dna polymerase holoenzymechi subunit (holc) genes, complete cds.) (nt:alternative putative start codon indicated at nt) 1978877_f3_758 6220 22791 441 146 35805405_f3_759 6221 22792 2973 990 3243 −9999 Heamophilus P43834 (ec:6.1.1.9) (de:valyl-trna synthetase, influenzae (valine--trna ligase) (valrs)) 14939406_f3_766 6222 22793 1818 605 274 −24 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 35802336_f3_767 6223 22794 2007 668 231 −15 mice|C57BL/ A45748 (cl:unassigned collagens) (sr:, house mouse) 6xCBA/CaJ hybrid 13160417_f3_776 6224 22795 360 119 120 −7 Aspergillus v1x1fj93.x GTC ORF with score 429 to: (ai:177837) fumigatus (or:Zae mays) (sr:, maize) 22270312_f3_777 6225 22796 291 96 128 −9 Klebsiella Contig442A GTC ORF with score 128 to: pneumonia (ai:7000777738) (or:Pseudomonas aeruginosa) 15726651_f3_779 6226 22797 873 290 106 −3 Schizosaccharo- Z95620 (sr:fission yeast) (de:s.pombe chromosome ii myces pombe cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 15729836_f3_780 6227 22798 483 160 247 −22 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 63/162.) (nt:rv1443c, (mtcy493.11), len: 161. unknown.) 13806906_f3_781 6228 22799 1506 501 144 −7 mice|C57BL/ E29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/CaJ hybrid 12706712_f3_782 6229 22800 1020 339 553 −53 Escherichia coli P33920 (de:hypothetical 37.8 kd protein in rply-prol intergenic region) 9798790_c1_794 6230 22801 696 231 154 −11 Neisseria U82701 (de:neisseria gonorrhoeae glutamine gonorrhoeae synthetase (glna) gene, partial cds.) (nt:orfz) 10283508_c1_797 6231 22802 1722 573 107 −3 Acinetobacter CONTIG161 GTC ORF with score 207 to: baumannii C (ai:7500981056) (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) 13026080_c1_801 6232 22803 1491 496 35798830_c1_804 6233 22804 876 291 206 −17 Klebsiella Contig442A GTC ORF with score 206 to: pneumoniae (ai:7000777765) (or:Pseudomonas aeruginosa) 24338180_c1_805 6234 22805 633 210 141 −8 Aegilops AF004358 (fn:chloroacetamide herbicide metabolism) squarrosa (ec:2.5.1.18) (de:aegilops squarrosa glutathione s-transferase tsi-1 mrna, complete cds.) (nt:gst isozyme) 6376028_c1_806 6235 22806 243 80 1462833_c1_808 6236 22807 1419 472 2239 −232 Pseudomonas A53735 (ec:2.4.2.—) aeruginosa 30738266_c1_810 6237 22808 2019 672 110 −3 eastern European U70653 (sr:eastern european house mouse) (de:mus house mouse musculus musculus sex determining protein (sry) gene, complete cds.) (nt:hmg box transcription factor) 34585183_c1_817 6238 22809 402 133 126567_c1_818 6239 22810 396 131 11758561_c1_828 6240 22811 2169 722 304 −26 Escherichia coli Q99390 (de:hypothetical 31.7 kd protein in trax-fino intergenic region (orfc)) 11980042_c1_829 6241 22812 1104 367 682 −67 Escherichia coli P39341 (de:hypothetical 39.8 kd protein in pepa-gntv intergenic region (o361)) 13150883_c1_834 6242 22813 822 273 935 −94 Escherichia coli P21516 (ec:5.—.—.—) (de:(queuosine biosynthesis protein quea)) 21532665_c1_836 6243 22814 519 172 221 −18 Klebsiella Contig546A GTC ORF with score 221 to: (ai:000777797) pneumonia (or:Pseudomonas aeruginosa) 22786716_c1_839 6244 22815 495 164 131 −7 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 36463130_c1_842 6245 22816 969 322 679 −67 Haemophilus P44590 (de:protein-export membrane protein secf) influenzae 26569781_c1_843 6246 22817 579 192 564 −54 Escherichia coli P37796 (de:hypothetical 18.9 kd protein in ndh-mdf intergenic region) 10681280_c1_845 6247 22818 1038 345 1041 −105 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:orf1) 4428193_c1_854 6248 22819 396 131 622 −61 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iacs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:nifu homolog; iron- binding protein involved in fes) 4812943_c1_855 6249 22820 333 110 516 −49 Azobacter Af010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:hypothetical protein involved in fes cluster) 12343880_c1_868 6250 22821 1203 400 358 −33 Escherichia coli P27434 (de:hypothetical 36.2 kd protein in ndk-gcpe intergenic region) 34475931_c1_869 6251 22822 555 184 135 −7 Saccharomyces P08640 (sr:baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 6928442_c1_873 6252 22823 663 220 240 −20 Escherichia coli H65027 12361016_c1_875 6253 22824 852 283 107 −5 Klebsiella Contig554A GTC ORF with score 324 to: pneumoniae (ai:7000842168) (or:Enterobacter cloacae) 26162627_c1_876 6254 22825 1500 499 1498 −153 Escherichia coli F65027 35630437_c1_878 6255 22826 876 291 649 −63 Escherichia coli Q47679 (de:hypothetical 28.9 kd protein in dnaq- gmha intergenic region) 985165_c1_880 6256 22827 462 153 104 −4 Klebsiella Contig519A GTC ORF with score 103 to: pneumoniae (ai:7000717465) (or:Homo sapiens) (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 14879201_c1_884 6257 22828 339 112 16698437_c1_885 6258 22829 1911 636 548 −53 Enterobacter CONTIG431 GTC ORF with score 648 to: cloacae (ai:7501742203) (or:Klebsiella pneumoniae) 31777180_c1_889 6259 22830 309 102 92 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 12582830_c1_890 6260 22831 372 124 289 −24 Pseudomonas D28119 (sr:pseudomonas aeruginosa, (strain pao1), aeruginosa dna, (clone ptn100)) (de:pseudomonas aeruginosa oprc gene for outer membrane protein c, complete cds.) 16222785_c1_891 6261 22832 999 332 1784 −184 Pseudomonas D28119 (sr:pseudomonas aeruginosa, (strain pao1), aeruginosa dna, (clone ptn100)) (de:pseudomonas aeruginosa oprc gene for outer membrane protein c, complete cds.) 32601381_c1_893 6262 22833 789 262 90 −1 Homo sapiens S78452 (cl:unassigned homeobox proteins:homoeobox homology:pou domain homology) (sr:, man) 34266588_c1_896 6263 22834 999 332 1221 −124 Bordetella S66937 (de:orf1 . . . orf3 {transposon-like sequence} pertussis (bordetella pertussis, genomic, 3 genes, 2300 nt).) 15727006_c1_898 6264 22835 900 299 578 −56 Cyanobacterium Q55759 (sr:pcc 6803,) (ec:3.5.4.16) (de:gtp synechocystis cyclohydrolase i, (gtp-chi-i)) 4425682_c1_899 6265 22836 441 146 32661681_c1_904 6266 22837 240 79 98 −4 Caenorhabditis Z69787 (de:caenorhabditis elegans cosmid c44c10, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 17067833_c1_922 6267 22838 1779 592 340 −30 Klebsiella Contig470A GTC ORF with score to: (ai:7000777883) pneumoniae (or:Pseudomonas aeruginosa) 35828586_c1_923 6268 22839 555 184 280 −25 Klebsiella Contig470A GTC ORF with score 418 to: pneumoniae (ai:7000787360) (or:Pseudomonas aeruginosa) 26739836_c1_924 6269 22840 1419 472 35946938_c1_934 6270 22841 591 196 541 −52 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) (nt:similar to vibrio secreted protein hcps81006) 26679093_c1_935 6271 22842 1983 660 116 −4 Homo sapiens D28113 (sr:homo sapiens spinal cord cdna to mrna, clone:hoprp1) (de:human mrna for mobp (myelin-associated oligodendrocytic basic protein), complete cds, clone hoprp1.) 16660081_c1_936 6272 22843 3369 1122 12364792_c1_939 6273 22844 1341 446 1819 −187 Pseudomonas U52431 (fn:algr-cognate sensor, negative regulator aeruginosa of) (sr:pseudomonas aeruginosa strain= pao568) (de:pseudomonas aeruginosa algr- cognate sensor algz (algz) gene, complete cds.) (nt:sensor of two-component system; homologous to s.) 12359691_c1_941 6274 22845 918 305 93 −1 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 2203166_c1_942 6275 22846 483 160 92 −5 Klebsiella Contig534A GTC ORF with score 92 to: (ai:7000777903) pneumoniae (or:Pseudomonas aeruginosa) 6738965_c1_943 6276 22847 894 297 1234 −125 Pseudomonas P48246 (ec:4.2.1.75) (de:iii cosynthease) aeruginosa (hydroxymethylbilane hydrolase (cyclizing))) 10239692_c1_945 6277 22848 465 154 98 −3 Medicago X99467 (sr:barrel medic) (de:m.truncatula enod20 truncatula gene.) 33828958_c1_946 6278 22849 957 318 136 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11814692_c1_947 6279 22850 450 149 113 −6 Rattus norvegicus AF007583 (sr:norway rat) (de:rattus norvegicus acetylcholinestrase-associated collagen (colq)mrna, complete cds.) (nt:collagen q) 11722958_c1_948 6280 22851 525 174 831 −83 Pseudomonas P21482 (de:hypothetical 17.8 kd protein in algr2 aeruginosa 5′region 15128775_c1_950 6281 22852 519 172 842 −84 Pseudomonas P15275 (de:algr2)) aeruginosa 16302312_c1_953 6282 22853 1200 399 1698 −175 Pseudomonas M32077 (sr:p.aeruginosa(stain pao, isolate pa02003) aeruginosa dna, form patien) (de:p.aeruginosa exopolysaccharide alginate regulatory protein (algpand algq) genes, complete cds.) (nt:alginate regulatory protein p; (put.); putative) 29735418_c1_954 6283 22854 402 133 567 −55 Pseudomonas P21484 (de:hypothetical 12.6 kd protein in algr3 aeruginosa 3′region. 13005031_c1_955 6284 22855 408 135 654 −64 Pseudomonas P21485 (de:hypothetical 13.0 kd protein in algr3 aeruginosa 3′region. 31460841_c1_964 6285 22856 402 133 107 −5 Homo sapiens Y13247 (sr:human) (de:homo sapiens fb19 mrna.) 13142016_c1_965 6286 22857 1245 414 6538331_c1_967 6287 22858 735 244 169 −13 Klebsiella Contig534A GTC ORF with score 169 to: pneumoniae (ai:7000777928) (or:Pseudomonas aeruginosa) 22767202_c1_975 6288 22859 2211 736 3747 −9999 Pseudomonas AB007598 (sr:pseudomonas aeruginosa dna) aeruginosa (de:pseudomonas aeruginosa gene for polyphosphate kinase andporphobilinogen synthase, complete and partial cds.) 3375283_c1_976 6289 22860 447 148 107 −6 Klebsiella Contig548A GTC ORF with score to: (ai:7000777937) pneumoniae (or:Pseudomonas aeruginosa) 2619452_c1_980 6290 22861 1989 662 598 −58 Salmonella U65941 (ec:2.3.1.—) (de:salmonella typhimurium o- choleraesuis antigen acetylase (oafa) gene, complete cds.) serotype (nt:oafa) typhimurium 3391077_c1_981 6291 22862 1479 492 2060 −213 Escherichia coli D65189 682032_c2_989 6292 22863 486 161 130 −8 Aquifex aeolicus F70460 11222515_c1_992 6293 22864 1614 537 188 −14 Klebsiella Contig556A GTC ORF with score 188 to: pneumoniae (ai:7000777953) (or:Pseudomonas aeruginosa) 22051681_c1_994 6294 22865 2136 711 190 −14 Klebsiella Contig556A GTC ORF with score 190 to: pneumoniae (ai:7000777955) (or:Pseudomonas aeruginosa) 31736388_c1_1000 6295 22866 513 170 92 −2 Dictyostelium P1428 (sr:,slime mold) (de:spore coat protein sp96) discoideum 13150840_c1_1004 6296 22867 1221 406 711 −70 Escherichia coli C65075 (cl:ubih protein) (ec:1.14.13.—) (mp:63 min) 35673291_c1_1005 6297 22868 957 318 116 −3 Micrococcus JQ0406 luteus 32604068_c1_1012 6298 22869 732 243 186 −14 Achromobacter A61183 georgiopolitanum 13019715_c1_1015 6299 22870 1710 569 1133 −115 Cyanobacterium S76051 (cl:sfub protein) (sr:pcc 6803,,pcc 6803) synechocystis (sr:pcc 6803,) 14303268_c1_1016 6300 22871 1209 402 1069 −108 Escherichia coli A56689 (ec:2.1.2.10) 35349131_c1_1017 6301 22872 3486 1161 3269 −9999 Escherichia coli P33195 (ec:1.4.4.2) (de:decarboxylase) (glycine cleavage system p-protein)) 33697768_c1_1022 6302 22873 306 101 164 −12 Pseudomonas P24564 (de:hypothetical 19.5 kd protein in pilt aeruginosa region (orf6)) 13753765_c1_1030 6303 22874 1407 468 1166 −118 Haemophilus P45268 (de:putative phosphate permease hi1604) influenzae 5161715_c1_1031 6304 22875 1182 393 894 −89 Escherichia coli P23908 (ec:3.5.1.16) (de:(n-acetylornithinase) (nao)) 30604167_c1_1032 6305 22876 225 74 128 −9 Enterobacter CONTIG491 GTC ORF with score 518 to: cloacae (ai:7501756091) (or:Klebsiella pneumoniae) 24729208_c1_1037 6306 22877 1899 632 241 −20 Klebsiella Contig407A GTC ORF with score 241 to: pneumoniae (ai:7000777998) (or:Pseudomonas aeruginosa) 36344026_c1_1043 6307 22878 762 253 871 −87 Yersinia Y08950 (de:y.enterocolitica ompr and envz genes.) enterocolitica 30572780_c1_1047 6308 22879 1443 480 427 −40 Klebsiella Contig458A GTC ORF with score 427 to: pneumoniae (ai:7000778008) (or:Pseudomonas aeruginosa) 26431961_c1_1049 6309 22880 594 197 104 −3 Canadian hard P10387 (sr:,wheat) (de:glutenin, high molecular winter wheat weight subunit dy 10 precursor) 24744086_c1_1052 6310 22881 1062 353 595 −58 Escherichia coli P45803 (de:hypothetical 32.5 kd protein in mrca-pcka intergenic region) 34472181_c1_1060 6311 22882 186 62 488275_c2_1061 6312 22883 264 87 16895412_c2_1062 6313 22884 588 195 112 −5 Klebsiella Contig554A GTC ORF with score 124 to: pneumoniae (ai:1500696584) (or:Equine herpesvirus 1) (sr:equine herpesvirus 1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 13020933_c2_1066 6314 22885 789 262 274 −24 Agrobacterium U59485 (de:agrobacterium tumefaciens putative tumefaciens (TI acetyltransferase (attr) gene, complete cds.) PLASMID (nt:gene required for bacterial attachment to PTIBO542) host) 11720708_c2_1067 6315 22886 990 329 130 −6 Cyanobacterium S76871 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 16900293_c2_1068 6316 22887 495 164 155 −11 soybean P16313 (sr:,soybean) (de:nodulin 21 (n-21)) 17058332_c2_1069 6317 22888 1260 419 36136693_c2_1070 6318 22889 1248 415 193 —15 Klebsiella Contig239A GTC ORF with score 217 to: pneumoniae (ai:7000815240) (or:Enterobacter cloacae) 1277037_c2_1077 6319 22890 204 67 116 −6 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region 12617782_c2_1083 6320 22891 606 201 114 −4 Human P36782 (de:regulatory protein e2) papillomavirus type 12 4385208_c2_1086 6321 22892 438 145 262 −23 Klebsiella Contig477A GTC ORF with score 262 to: pneumoniae (ai:7000778047) (or:Pseudomonas aeruginosa) 36063505_c2_1090 6322 22893 1002 333 132 −6 Enterobacter CONTIG513 GTC ORF with score 694 to: cloacae (ai:7000769491) (or:Pseudomonas aeruginosa) 35391465_c2_1093 6323 22894 585 194 2604511_c2_1097 6324 22895 2430 809 1768 −182 Klebsiella Contig398A GTC ORF with score 3674 to: pneumoniae (ai:7000829129) (or:Enterobacter cloacae) 13145715_c2_1100 6325 22896 1470 489 326 −29 Klebsiella Contig398A GTC ORF with score 488 to: (ai:700013900) pneumoniae (or:Enterobacter cloacae) 32681330_c2_1101 6326 22897 1011 336 374 −36 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 159/162.) (nt:rv3833, (mtcy01a6.36c), len 263. possible) 16277030_c2_1116 6327 22898 471 156 154 −11 Enterobacter CONTIG480 GTC ORF with score 154 to: cloacae (ai:7000778077) (or:Pseudomonas aeruginosa) 16885205_c2_1117 6328 22899 306 101 299 −26 Escherichia coli P21516 (ec:5.—.—.—) (de:(queuosine biosynthesis protein quea)) 665905_c2_1118 6329 22900 1131 376 1428 −146 Shigella flexneri Q54177 (ec:2.4.2.29) (de:protein vacc)) 35751432_c2_1120 6330 22901 1890 629 369 −31 Escherichia coli P19673 (de:protein-export membrane protein secd) 10442905_c2_1126 6331 22902 645 214 95 −2 Gallus gallus Q05063 (sr:,chicken) (ec:1.4.3.13) (de:protein-lysine domesticus 6-oxidase precursor, (lysyl oxidase)) 11907713_c2_1127 6332 22903 402 133 93 −3 Azospirillum P30667 (de:nif-specific regulatory protein) brasilense 22128542_c2_1128 6333 22904 1263 420 1871 −193 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:pyridoxal phosphate-dependent 1-cysteine) 10631967_c2_1129 6334 22905 672 223 615 −60 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:member of a heat-shock-cognate molecular chaperone) 34555300_c2_1130 6335 22906 1872 623 2479 −257 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:member of a heat-shock-cognate molecular chaperone) 12932833_c2_1131 6336 22907 345 114 587 −57 Pseudomonas Q51383 (de:ferredoxin, 2fe-2s) aeruginosa 24032667_c2_1133 6337 22908 855 284 134 −9 Klebsiella Contig213A GTC ORF with score 134 to: pneumoniae (ai:7000778094) (or:Pseudomonas aeruginosa) 16109655_c2_1134 6338 22909 1008 335 980 −99 Pseudomonas JC5302 (cl:tetratricopeptide repeat homology) aeruginosa 25862541_c2_1137 6339 22910 2088 695 107 −2 no gb taxonomy P10238 (sr:type 1/17,) (de:transcriptional regulator match ie63 (vmw63) (icp27)) 13144157_c2_1138 6340 22911 309 102 215 −17 Salmonella AF047040 (de:salmonella typhimurium histidyl-trna choleraesuis synthetase (hiss) gene, complete cds.) serotype (nt:aminoacyl-trna synthetase) typhimurium 5161292_c2_1139 6341 22912 1338 445 544 −52 Escherichia coli P77774 (de:hypothetical 41.9 kd protein in xsea-hiss intergenic region) 35445830_c2_1141 6342 22913 1323 440 1066 −108 Escherichia coli P77806 (ec:2.6.1.—) (de:hypothetical aminotransferase ybdl,) 33723893_c2_1144 6343 22914 480 159 171 −11 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 6343793_c2_1145 6344 22915 705 234 134 −7 Klebsiella Contig519A GTC ORF with score 123 to: (ai:278676) pneumoniae (or:Caenorhabditis elegans) (sr:caenorhabditis elegans strain=bristol n2) (de:caenorhabditis elegans cosmid t28h11.) (nt:glycine-rich, similar to sea urchin (hemicentrotus) 36066302_c2_1147 6345 22916 477 158 5183330_c2_1150 6346 22917 447 148 200 −16 Klebsiella Contig407A GTC ORF with score 200 to: pneumoniae (ai:7000778111) (or:Pseudomonas aeruginosa) 5198832_c2_1152 6347 22918 450 149 283 −25 Klebsiella Contig407A GTC ORF with score 283 to: pneumoniae (ai:7000778113) (or:Pseudomonas aeruginosa) 22792066_c2_1154 6348 22919 1236 411 3258233_c2_1155 6349 22920 456 151 92 −4 Pseudochirops P42145 (de:sperm protamine p1) cupreus 10728405_c2_1158 6350 22921 1422 473 2460 −255 Pseudmonas D28119 (sr:pseudomonas aeruginosa, (strain poa1), aeruginosa dna, (clone ptn100)) (de:pseudomonas aeruginosa oprc gene for outer membrane protein c, complete cds.) (nt:putative) 16258250_c2_1164 6351 22922 918 305 211 −17 Escherichia coli P76053 (de:hypothetical 21.5 kd protein in ogt-dbpa intergenic region) 35631941_c2_1170 6352 22923 2445 814 29969555_c2_1171 6353 22924 276 91 113 −6 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 6720680_c2_1173 6354 22925 1446 481 16302331_c2_1182 6355 22926 426 141 290 −26 Klebsiella Contig470A GTC ORF with score 290 to: pneumoniae (ai:7000778143) (or:Pseudomonas aeruginosa) 9769842_c2_1183 6356 22927 414 137 121 −6 human U92288 (fn:helicase, helicase-primase complex) herpesvirus type (de:human herpesvirus 6 serotype b putative 6 HHV-6 major immediate-early genes.) (nt:similar to hhv6a u86, region ie-b) 13019581_c2_1185 6357 22928 492 163 339 −31 Klebsiella Contig470A GTC ORF with score 388 to: pneumoniae (ai:7000787644) (or:Pseudomonas aeruginosa) 17071938_c2_1192 6358 22929 453 150 111 −6 Aspergillus Contig8932 GTC ORF with score 246 to: (ai:175141) fumigatus (or:Chlamydomonas eugametos) (de:chlamydomonas eugametos wp6 mrna, complete cds.) (nt:amino acid feature: n- glycosylation sites, aa 41 . . . ) 21767666_c2_1195 6359 22930 2217 738 820 −82 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) 5292788_c2_1203 6360 22931 1053 350 405 −38 Klebsiella Contig441A GTC ORF with score 868 to: pneumoniae (ai:7000835840) (or:Enterobacter cloacae) 13769683_c2_1207 6361 22932 036 311 1245 −127 Pseudomonas P26275 (de:positive alginate biosynthesis regulatory aeruginosa protein) 16886466_c2_1208 6362 22933 1050 340 1536 −157 Pseudomonas Q60169 (ec:4.3.1.8) (de:synthase) (hmbs) (pre- aeruginosa uroporphyrinogen synthase)) 35661386_c2_1211 6363 22934 1344 447 359 −33 Escherichia coli P09128 (de:hemy protein) 35785092_c2_1215 6364 22935 462 153 357 −33 Pseudomonas JQ0147 aeruginosa 2617716_c2_1218 6365 22936 450 149 176 −13 Pleuronectes U39735 (de:pleuronectes americanus sperm americanus chromatin protein hmrbnp-1 mrna, partial cds.) (nt:hmrbnp-1; crosslinks nucleosomes in sperm) 2539581_c2_1219 6366 22937 423 140 141 −9 Arabidopsis P40602 (sr:,mouse-ear cress) (de:anter-specific thaliana proline-rich protein apg precursor) 26384703_c2_1224 6367 22938 582 193 26594431_c2_1225 6368 22939 765 254 728 −72 Haemorphilus P43932 (de:hypothetical protein hi0056) influenzae 34553200_c2_1227 6369 22940 1980 659 399 −36 Treponema AE001265 (de:treponema pallidum section 81 of 87 of pallidum the complete genome.) (nt:similar to gb:x73124 sp:p39595 pid:413951) 32502333_c2_1228 6370 22941 549 182 300 −26 Escherichia coli C64767 666032_c2_1233 6371 22942 1017 338 1703 −175 Pseudomonas Q59643 (ec:4.2.1.24) (de:synthase) (alad) (aladh)) aeruginosa 2135816_c2_1237 6372 22943 1743 580 436 −41 Escherichia coli AE000454 (de:escherichia coli k-12 mg1655 section 344 of 400 of the complete genome.) (nt:o127; 100 pct identical to 108 amino acids of) 15870956_c2_1244 6373 22944 369 122 194 −16 Klebsiella Contig534A GTC ORF with score to: pneumoniae (ai:7000778305) (or:Pseudomonas aeruginosa) 18814845_c2_1250 6374 22945 1275 424 185 −11 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 16852018_c2_1251 6375 22946 2790 929 3160 −9999 Escherichia coli P37624 (de:hypothetical abc transporter atp-binding protein yhih) 33853458_c2_1252 6376 22947 1128 375 1306 −133 Escherichia coli P31993 (de:hypothetical 41.1 kd protein in rhsb-pit intergenic region) 12788955_c2_1254 6377 22948 822 273 123 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 35347666_c2_1257 6378 22949 855 284 108 −3 Homo sapiens AB014591 (sr:homo sapiens adult male brain cdna to mrna, clone_:pbluescripti) (de:homo sapiens mrna for kiaa0691 protein, complete cds.) 32322257_c2_1258 6379 22950 687 228 104 −2 Actinomyces S20590 (ec:3.2.1.18) viscosus 10005406_c2_1262 6380 22951 621 206 329 −30 Acinetobacter CONTIG211 GTC ORF with score 329 to: baumannii C (ai:7000778223) (or:Pseudomonas aeruginosa) 12391416_c2_1263 6381 22952 1239 412 126 −5 Pseudomonas P15276 (de:algr3)) aeruginosa 11729218_c2_1267 6382 22953 1602 533 446 −42 Escherichia coli P77559 (de:hypothetical transcriptional regulator in mlc-asr intergenic region) 16817130_c2_1275 6383 22954 441 146 432 −40 Escherichia coli P23884 (de:glycine cleavage system h protein) 24742656_c2_1280 6384 22955 978 325 92 −2 common tobacco S34666 (cl:phaseolus glycine-rich protein 1.0) (sr:, common tobacco) 12750763_c2_1283 6385 22956 348 115 113 −6 Homo sapiens P12110 (sr:,human) (de:collagen alpha 2(vi) chain (fragment)) 16880206_c2_1285 6386 22957 474 157 98 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein sp96) discoideum 16297906_c2_1295 6387 22958 378 125 129 −9 Enterobacter CONTIG431 GTC ORF with score 129 to: cloacae (ai:7000778256) (or:Pseudomonas aeruginosa) 31375680_c2_1297 6388 22959 1269 422 789 −79 Klebsiella Contig373A GTC ORF with score 1134 to: pneumoniae (ai:7000837509) (or:Enterobacter cloacae) 12165768_c2_1298 6389 22960 1116 371 607 −59 Enterobacter CONTIG487 GTC ORF with score 797 to: cloacae (ai:7501738308) (or:Klebsiella pneumoniae) 5333455_c2_1301 6390 22961 1506 501 574 −56 Salmonella P08982 (ec:2.7.3.—) (de:osmolarity sensor protein choleraesius envz,) serotype typhimurium 30213265_c2_1303 6391 22962 1119 372 258 −22 Enterobacter CONTIG399 GTC ORF with score 258 to: cloacae (ai:7000778264) (or:Pseudomonas aeruginosa) 35317961_c2_1305 6392 22963 504 167 334 −30 Escherichia coli P45802 (de:hypothetical 15.5 kd protein in mrca-pcka intergenic region (o133)) 24719792_c2_1309 6393 22964 1590 529 1336 −136 Bacillus P54418 (ec:4.1.1.49) (de:phosphoenolpyruvate subtilis/Bacillus carboxykinase (atp),) globigii 19587642_c2_1311 6394 22965 666 221 480 −46 Cyanobacterium S75047 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 24739430_c3_1312 6395 22966 645 214 3313255_c3_1313 6396 22967 741 246 323 −29 Drosophilia S58776 (mp:3) melanogaster 14926905_c3_1320 6397 22968 411 136 95 −3 equine D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for membrane EVH-1 glycoprotein, complete cds.) 34658143_c3_1327 6398 22969 630 209 262 −22 Caenorhabditis Z69637 (de:caenorhabditis elegans cosmid f35g2, elegans complete sequence.) (nt:predicted using genefinder; similarity to e.coli) 4692716_c3_1330 6399 22970 1029 342 129 −5 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 31376093_c3_1332 6400 22971 636 211 92 −4 Klebsiella Contig556A GTC ORF with score 188 to: pneumoniae (ai:7000777953) (or:Pseudomonas aeruginosa) 14864755_c3_1334 6401 22972 420 139 145 −10 Klebsiella Contig525A GTC ORF with score 357 to: pneumoniae (ai:7000829161) (or:Enterobacter cloacae) 13963966_c3_1335 6402 22973 840 279 275 −24 Klebsiella Contig525A GTC ORF with score 357 to: pneumoniae (ai:7000829161) (or:Enterobacter cloacae) 32292942_c3_1339 6403 22974 1032 343 158 −11 Streptococcus CONTIG677 GTC ORF with score 158 to: pneumoniae D (ai:7000778300) (or:Pseudomonas aeruginosa) 24250135_c3_1342 6404 22975 573 190 94 −2 Homo sapiens A22940 (cl:cytoskeletal keratin) (sr:, man) 5213542_c3_1344 6405 22976 747 248 376 −35 Enterobacter CONTIG446 GTC ORF with score 97 to: (ai:1500696975) cloacae (or:Schizosaccharomyces pombe) (sr:fission yeast) (de:s.pombe chromosome ii cosmid c3d6.) (nt:spc3d614c, unknown; partial; serine rich.) 31891467_c3_1351 6406 22977 585 194 174 −13 Klebsiella Contig398A GTC ORF with score 210 to: pneumoniae (ai:7000813899) (or:Enterobacter cloacae) 11064653_c3_1352 6407 22978 555 184 437 −41 Acinetobacter CONTIG204 GTC ORF with score 437 to: baumannii C (ai:7000778313) (or:Pseudomonas aeruginosa) 32286716_c3_1358 6408 22979 1167 388 496 −47 Escherichia coli P39340 (de:hypothetical 40.4 kd protein in pepa-gntv intergenic region (o366)) 1258258_c3_1359 6409 22980 1083 360 96 −3 Klebsiella Contig398A GTC ORF with score 96 to: (ai:7000778320) pneumoniae (or:Pseudomonas aeruginosa) 33853130_c3_1361 6410 22981 1617 538 688 −68 Escherichia coli E64862 24088332_c3_1363 6411 22982 483 160 100 −3 Caenorhabditis AF040642 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid c50d2.) (nt:similar to cuticular collagen; codded for by c.) 20167336_c3_1367 6412 22983 351 116 252 −21 Escherichia coli P19677 (de:hypothetical 11.9 kd protein in tgt-secd intergenic region (orf12)) 29926067_c3_1368 6413 22984 1398 465 1083 −109 Escherichia coli P19673 (de:protein-export membrane protein secd) 32675937_c3_1373 6414 22985 897 298 327 −30 Klebsiella Contig437A GTC ORF with score 702 to: pneumoniae (ai:7000840276) (or:Enterobacter cloacae) 1212691_c3_1375 6415 22986 783 260 1079 −109 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:cysc2) 26805155_c3_1376 6416 22987 510 169 634 −62 Azotobacter AF010139 (de:azotobacter vinelandii iron-sulfur cluster vinelandii assembly gene cluster, suhb, cyse2, iscs, iscu, isca, hscb, hsca and fdx genes complete cds; ndk gene, partial cds.) (nt:orf2) 24738205_c3_1384 6417 22988 405 134 344 −31 Pseudomonas Q51384 (de:hypothetical 7.8 kd protein in pepb-fdx aeruginosa intergenic region) 32520762_c3_1385 6418 22989 603 200 689 −68 Pseudomonas Q59636 (ec:2.7.4.6) (de:nucleoside disphosphate aeruginosa kinase, (ndk) (ndp kinase)) 36380330_c3_1386 6419 22990 1164 387 1951 −201 Pseudomonas Q51385 (de:hypothetical 41.7 kd protein in pilf-ndk aeruginosa intergenic region (orf1)) 35835192_c3_1390 6420 22991 1644 547 1374 −140 Escherichia coli P27433 (de:gcpe protein (protein e)) 6410193_c3_1391 6421 22992 1053 350 1116 −113 Escherichia coli A23890 (cl:histidine--trna ligase:amino acid--trna ligase repeat homology:histidine--trna ligase homology) (ec:6.1.1.21) (mp:54 min) 35351665_c3_1397 6422 22993 777 258 123 −6 mice S50883 (sr:mice macrophage) (deputative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 34494805_c3_1400 6423 22994 429 142 103 −4 Saccharomyces P47179 (sr:,baker's yeast) (de:precursor) cerevisiae 12586656_c3_1408 6424 22995 408 135 204 −16 Klebsiella Contig407A GTC ORF with score 204 to: pneumoniae (ai:7000778369) (or:Pseudomonas aeruginosa) 2390837_c3_1409 6425 22996 678 225 24431527_c3_1410 6426 22997 2049 682 1735 −179 Pseudomonas D28119 (sr:Pseudomonas aeruginosa, (strain pao1), aeruginosa dna, (clone ptn100)) (de:pseudomonas aeruginosa oprc gene for outer membrane protein c, complete cds.) 11197540_c3_1415 6427 22998 534 177 114 −7 Aspergillus Contig6126 GTC ORF with score 114 to: fumigatus (ai:7000778376) (or:Pseudomonas aeruginosa) 14942558_c3_1419 6428 22999 510 169 238 −20 Bordetella S66937 (de:orf1 . . . orf3 {transposon-like sequence} pertussis (bordetella pertussis, genomic, 3 genes, 2300 nt).) 16218881_c3_1421 6429 23000 471 156 11211456_c3_1423 6430 23001 810 269 241 −20 Mucuna hassjoo S54845 (ec:3.5.4.16) 32598841_c3_1425 6431 23001 600 199 104 −2 Alphaherpesvirus P11675 (sr:indiana-funkhauser/becker, prv) pseudorabies (de:immediate-early protein ie 180) virus PRV 16485433_c3_1427 6432 23003 1068 355 97 −2 mice|C67BL/ AB011550 (sr:mus musculus testis cdna to mrna) 6xCBA/CaJ (de:mus musculus tctex-3 mrna, complete hybrid cds.) (nt:drosophila policomblike-related gene containing phd) 32635961_c3_1430 6433 23004 1704 567 4585316_c3_1436 6434 23005 1878 625 105 −3 Aeromonas U56832 (de:aeromonas hydrophilia fk506 binding hydrophila protein (fkpa) gene, complete cds in 3.9 kb fragment.) (nt:orf5; no significant similarity with known) 12238556_c3_1438 6435 23006 393 130 134 −8 blue mussel AF029249 (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 12788556_c3_1445 6436 23007 1923 640 14666317_c3_1446 6437 23008 2307 768 527 −49 Klebsiella Contig470A GTC ORF with score 767 to: pneumoniae (ai:7000817331) (or:Enterobacter cloacae) 16126031_c3_1452 6438 23009 447 148 157 −10 equine D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for membrane EVH-1 glycoprotein, complete cds.) 24691256_c3_1455 6439 23010 363 120 120 −6 equine D88733 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for membrane EVH-1 glycoprotein, complete cds.) 4163878_c3_1461 6440 23011 1215 404 30663591_c3_1465 6441 23012 873 290 95 −1 Mycobacterium Z95890 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 79/162.) (nt:rv1759c, (mtcy28.25c), wag22, len: 914. member of) 10442807_c3_1468 6442 23013 321 106 99 −5 Klebsiella Contig534A GTC ORF with score 99 to: (ai:7000778429) pneumoniae (or:Pseudomonas aeruginosa) 35370306_c3_1471 6443 23014 1146 381 291 −26 Escherichia coli P09127 (ec:2.1.107) (de:iii methylase) (orf x)) 34630412_c3_1475 6444 23015 654 217 854 −85 Pseudomonas P21483 (de:hypothetical 17.3 kd protein in algr2 aeruginosa 5′region 24507141_c3_1480 6445 23016 915 304 181 −12 Plasmodium vivax M34697 (sr:p.vivax (strain thai; isolate nyu thai) sporozoite dna) (de:p.vivax circumsporozoite protein gene, complete cds.) (nt:circumsporozoite protein) 2634525_c3_1481 6446 23017 2259 752 1780 −183 Escherichia coli P45535 (de:hypothetical abc transproter atp-binding protein yhes) 35798331_c3_1483 6447 23018 834 277 299 −26 Escherichia coli P27847 (de:hypothetical 15.4 kd protein in recq-pldb intergenic region (f138)) 1067091_c3_1489 6448 23019 792 263 154 −11 Klebsiella Contig467A GTC ORF with score 154 to: pneumoniae (ai:7000778450) (or:Pseudomonas aeruginosa) 17058402_c3_1498 6449 23020 474 157 192 −15 Klebsiella Contig488A GTC ORF with score 192 to: pneumonia (ai:7000778459) (or:Pseudomonas aeruginosa) 31488166_c3_1500 6450 23021 1344 447 2013 −208 Pseudomonas P52155 (de:transcription termination factor rho) fluorescens 6454633_c3_1503 6451 23022 1206 401 114 −4 Caenorhabditis Z70682 (de:caenorhabditis elegans cosmid f08g5, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 22363915_c3_1504 6452 23023 1083 360 346 −31 Yersinia P37911 (ec:1.18.1.—) (de:cdp-6-deoxy-delta-3,4- pseudo- glocoseen reductase, (e3)) tuberculosis 31667707_c3_1505 6453 23024 1452 483 803 −80 Enterobacter CONTIG506 GTC ORF with score 803 to: cloacae (ai:7000778466) (or:Pseudomonas aeruginosa) 11173328_c3_1506 6454 23025 1206 401 144 −8 Klebsiella Contig559A GTC ORF with score 219 to: pneumoniae (ai:7000766725) (or:Pseudomonas aeruginosa) 4384465_c3_1507 6455 23026 564 187 119 −5 Araneus U47855 (de:araneus diadematus fibroin-3 (adf-3) didaematus mrna, partial cds.) 14538516_c3_1508 6456 23027 1194 397 1030 −104 Escherichia coli P37626 (de:(f355)) 15097330_c3_1509 6457 23028 327 108 91 −3 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 2129638_c3_1521 6458 23029 615 204 194 −16 Acinetobacter CONTIG129 GTC ORF with score 194 to: baumannii C (ai:7000778482) (or:Pseudomonas aeruginosa) 4534393_c3_1522 6459 23030 1344 447 1098 −111 Cyanobacterium S76440 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 25598518_c3_1523 6460 23031 669 222 115 −5 Enterobacter CONTIG496 GTC ORF with score 121 to: cloacae (ai:7000774304) (or:Pseudomonas aeruginosa) 11739791_c3_1524 6461 23032 516 171 98 −4 Klebsiella Contig541A GTC ORF with score 138 to: pneumoniae (ai:1500696584) (or:Equine herpesvirus 1) (sr:equine herpesvirus 1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 29805340_c3_1525 6462 23033 1506 501 781 −77 Escherichia coli B65075 (cl:ubih protein) (mp:63 min) 31855441_c3_1531 6463 23034 1317 438 655 −64 Cyanobacterium S74691 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 3963331_c3_1532 6464 23035 1965 654 11822717_c3_1536 6465 23036 1659 552 115 −4 Caenorhabditis Z49131 (de:caenorhabditis elegans cosmid zc373, elegans complete sequence.) (nt:similar to cuticular collagen; cdna est embl:d66257) 12317916_c3_1537 6466 23037 486 161 101 −3 Brugia malayi M38435 (sr:b.malayi dna) (de:brugia malayi probe pbmcw3.) 22526056_c3_1538 6467 23038 1029 342 153 −11 Enterobacter CONTIG493 GTC ORF with score 153 to: cloacae (ai:7000778499) (or:Pseudomonas aeruginosa) 16298911_c3_1543 6468 23039 615 204 248 −21 Klebsiella Contig446A GTC ORF with score 437 to: pneumoniae (ai:7000798059) (or:Pseudomonas aeruginosa) 15755058_c3_1545 6469 23040 441 146 102 −3 human U92288 (fn:helicase, helicase-primase complex) herpesvirus type 6 (de:human herpesvirus 6 serotype b putative HHV-6 major immediate-early genes.) (nt:similar to hhv6a u86, region ie-b) 33673842_c3_1548 6470 23041 750 249 622 −61 Haemophilus P44271 (de:hypothetical protein hi1603) influenzae 288333_c3_1549 6471 23042 1380 459 36369033_c3_1550 6472 23043 633 210 92 −2 no gb taxonomy P17588 (sr:type I/f,) (de:latency-related protein 1) match 32547308_c3_1552 6473 23044 1107 368 120 −7 Klebsiella Contig475A GTC ORF with score 120 to: pneumoniae (or:Pseudomonas aeruginosa) 29820443_c3_1553 6474 23045 1404 467 1167 −118 Escherichia coli P08205 (ec:2.3.1.1) (de:synthase) (ags)) 16297706_c3_1555 6475 23046 591 196 101 −3 Aspergillus Contig4770 GTC ORF with score 277 to: (ai:69657) fumigatus (or:Human herpesvirus 4) (cl:epstein-barr virus nuclear antigen) 31252077_c3_1556 6476 23047 1137 378 196 −15 Enterococcus CONTIG463 GTC ORF with score 196 to: faecalis (ai:7000778517) (or:Pseudomonas aeruginosa) 30753778_c3_1557 6477 23048 651 216 92 −4 Enterococcus CONTIG269 GTC ORF with score 92 to: (ai:7000778518) faecalis (or:Pseudomonas aeruginosa) 509417_c3_1559 6478 23049 234 77 129 −9 Klebsiella Contig373A GTC ORF with score 436 to: pneumoniae (ai:7000837556) (or:Enterobacter cloacae) 32550681_c3_1562 6479 23050 519 172 91 −2 Saccaromyces P40552 (sr:,baker's yeast) (de:hypothetical 26.3 kd cerevisiae protein in pdr11-faa3 intergenic region) 16849155_c3_1567 6480 23051 1080 359 106 −2 Molluscum U60315 (de:molluscum contagiosum virus subtype 1, contagiosum virus complete genome.) (nt:contains large subtype 1 predicted non-globular regions and) 12158141_c3_1568 6481 23052 1026 341 134 −5 domestic horse U62528 (sr:domestic horse) (de:equus caballus type ii collagen mrna, complete cds.) 4859705_c3_1574 6482 23053 705 234 174 −13 Plasmid pAH4 JC2320 5332842_f1_2 6483 23054 231 76 127 −8 Agrobacterium Y13942 (fn:unknown)(de:agrobacterium radiobacter radiobacter genomic dna for glycerol trinitratereductase.) 16038558_f1_3 6484 23055 540 179 412 −38 Escherichia coli C64923 (cl:hypothetical protein hi0135) 12212578_f2_4 6485 23056 390 129 214 −16 Pseudomonas D86947 (fn:chemotactic responses toward amino aeruginosa acids) (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa gene for chemotatic transducer, complete cds.) 10276081_f3_6 6486 23057 1059 352 146 −10 Acinetobacter CONTIG228 GTC ORF with score 151 to: baumannii C (ai:4000714431) (or:Agrobacterium radiobacter) (fn:unknown) (de:agrobacterium radiobacter genomic dna for glycerol trinitratereductase.) 895919_c1_7 6487 23058 507 168 189 −15 Klebsiella Contig543A GTC ORF with score 335 to: pneumoniae (ai:7000782681) (or:Pseudomonas aeruginosa) 11922788_f1_1 6488 23059 1038 345 835 −83 Bradyrhizobium Q03073 (ec:1.9.3.1) (de:subunit)) japonicum 13145126_f1_7 6489 23060 1617 538 1605 −165 Rhizobium Z80339 (fn:subunit i of terminal cytochrome c leguminosarum oxidase) (de:r.leguminosarum fixnd and fixod genes.) 14883436_f1_10 6490 23061 963 320 472 −45 Paracoccus U34353 (fn:di-heme cytochrome c of cytochrome dentrificans cbb3) (de:paracoccus denitrificans cco locus, frn-like protein (fnrn), cytochrome cbb3 subunit i (ccon), mono-heme cytochrome c (ccoo), di-heme cytochrome c (ccop), ccoq (ccoq) and ccog (ccog) genes, c . . . 30557280_f1_12 6491 23062 639 212 95 −3 Aspergillus Contig6446 GTG ORF with score 104 to: fumigatus (ai:7000809234) (or:Pseudomonas aeruginosa) 26380317_f1_13 6492 23063 591 196 11058181_f1_16 6493 23064 315 104 109 −7 Aspergillus Contig10160 GTC ORF with score 92 to: (ai:99171) fumigatus (or:Dictyostelium discoideum) (de:dictyostelium discoideum sp96 gene for spore coated protein sp96.) 33866291_f1_18 6494 23065 456 151 116 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 25427340_f1_22 6495 23066 1521 506 2392 −248 Pseudomonas P77915 (ec:1.—.—.—) (de:(coproporphyrinogenase) aeruginosa (coprogen oxidase)) 24869805_f1_27 6496 23067 714 237 908 −91 Pseudomonas Q04633 (ec:2.4.2.7) (de:probable adenine aeruginosa phosphoribosyltransferase, (aprt)) 5256517_f1_33 6497 23068 1617 538 1338 −136 Pseudomonas AF090329 (de:pseudomonas fluorescens cyclohexanone fluorescens monooxygenase homolog gene, partial cds; lactone-specific esterase (estf1) gene, complete cds; and alkane-1 monooxygenase homolog gene; partial cds.) (nt:orf1) 29817540_f1_35 6498 23069 717 238 367 −35 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 101/162.) (nt:rv2295, (mtcy339.15c),: 212. unknown) 2479162_f1_36 6499 23070 1419 472 95 −2 Aspergillus Contig5155 GTC ORF with score 95 to: (ai:7000778585) fumigatus (or:Pseudomonas aeruginosa) 10394455_f1_39 6500 23071 591 196 253 −20 California red AF023459 (sr:california red abalone) (de:haliotis abalone rufescens lustrin a mrna, complete cds.) (nt:extracellular matrix protein; modular structure) 13910985_f1_40 6501 23072 1884 627 341 −30 Enterobacter CONTIG438 GTC ORF with score 341 to: cloacae (ai:7000778589) (or:Pseudomonas aeruginosa) 12995781_f1_45 6502 23073 477 158 593 −58 Shigella flexneri P04336 (de:mercuric transport protein (mercury ion transprot protein)) 14073580_f1_46 6503 23074 336 112 372 −34 Pseudomonas U80214 (fn:transport) (de:pseudomonas stutzeri stutzeri plasmid ppb merr(merr), mert(mert), merp(merp), mera(mera), merd(merd), urf1 (urf1), urf2(urf2), delta-tnia-like protein, and dna-invertase genes, complete cds; and delta- tnir pseudogene, co . . . 35207040_f2_47 6504 23075 369 122 212 −17 Sphigomonas sp. Y13118 (sr:sphingomonas sp.) (de:sphingomonas sp. fdx1 gene and 4 orf's.) (nt:orf3) 14563340_f2_48 6505 23076 693 230 584 −57 Rhizobium S39989 (cl:fixo protein) meliloti (megaplasmid pRME41B SYM) 22866656_f2_51 6506 23077 477 158 113 −5 Homo sapiens P23246 (sr:,human) (de:ptb-associated splicing factor (psf)) 36142667_f2_53 6507 23078 273 90 22908156_f2_56 6508 23079 1467 488 783 −78 Rhodobacter AF016223 (de:rhodobacter capsulatus phosphoribosyl- capsulatus atp pyrophosphohydrolase(hise), cylase(hisf), phosphoribosylformimino-praic ketoisomerase(hisa), cytochrome ccb3 oxidase subunit i(ccon), mono- hemecytochrome co(ccoo), cytochrome oxidase . . . 32589593_f2_58 6509 23080 1686 561 188 −11 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 25909541_f2_59 6510 23081 672 223 121 −7 Bradyrhizobium X95634 (de:b.japonicum fixg, fixh, fixi and fixs japonicum genes.) 16146007_f2_60 6511 23082 765 254 150 −7 Micrococcus JQ0405 luteus 5350805_f2_62 6512 23083 417 138 116 −6 equine D88734 (sr:equine herpesvirus 1 (strain:bk343, herpesvirus type 1 isolate:3f clone) dna) (de:equine herpesvirus EVH-1 1 dna for membrane glycoprotein, complete cds.) 22928932_f2_71 6513 23084 891 296 369 −34 Escherichia coli A64916 10416682_f2_84 6514 23085 546 181 124 −6 Persian tobacco U88587 (sr:persian tobacco) (de:nicotiana alata 120 kda style glycoprotein (naprp5) mrna, complete cds.) (nt:style-specific protein possessing features of) 4964692_f2_93 6515 23086 822 273 21677066_f2_95 6516 23087 402 133 452 −43 Entero- S07447 bacteriaceae 14883436_f3_101 6517 23088 933 310 464 −44 stem-nodulating X74410 (sr:stem-nodulating bacterium) bacterium (de:a.caulinodans genes fixn, fixo, fixq, fixp and fixg.) 22073452_f3_105 6518 23089 612 203 577 −56 Rhizobium S39989 (cl:fixo protein) meliloti (megaplasmid pRME41B SYM) 11847816_f3_111 6519 23090 2469 822 1018 −103 Rhizobium O33533 (ec:3.6.1.—) (de:(ec 3.6.1.—)) leguminosarum 32510155_f3_112 6520 23091 864 287 181 −14 Helicobacter E64627 pylori 26755256_f3_116 6521 23092 753 250 1222 −124 Pseudomonas P23926 (de:transcriptional activator protein anr) aeruginosa 34547161_f3_118 6522 23093 927 308 374 −34 Pseudomonas X57736 (de:p.aeruginosa anr gene for positive aeruginosa control element anr.) (nt:orf d) 21532635_f3_119 6523 23094 588 195 279 −24 Escherichia coli B64916 35556712_f3_121 6524 23095 267 88 21586426_f3_123 6525 23096 1899 632 674 −68 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 54/162.) (nt:rv1245c, (mtv006.17c), len: 276. unknown) 4114826_f3_128 6526 23097 489 162 161 −12 Enterobacter CONTIG438 GTC ORF with score 416 to: cloacae (ai:7501759612) (or:Klebsiella pneumoniae) 24901717_f3_129 6527 23098 978 325 184 −14 Escherichia coli U82664 (de:escherichia coli minutes 9 to 11 genomic sequence.) (nt:hypothetical protein) 14142586_f3_135 6528 23099 1398 465 323 −27 Klebsiella Contig550A GTC ORF with score 323 to: pneumoniae (ai:7000778684) (or:Pseudomonas aeruginosa) 25862918_f3_136 6529 23100 297 98 270 −23 Pseudomonas P04139 (de:hypothetical mercuric resistance protein aeruginosa merc) 36413531_c1_139 6530 23101 594 197 205 −17 Klebsiella Contig505A GTC ORF with score 236 to: pneumoniae (ai:7000785901) (or:Pseudomonas aeruginosa) 14948761_c1_145 6531 23102 1077 358 940 −94 Escherichia coli P06710 (ec:2.7.7.7) (de:dna polymerase iii subunits gamma and tau,) 2911405_c1_146 6532 23103 405 134 136 −8 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:cbna-1 nuclear protein) 31426341_c1_148 6533 23104 1152 383 110 −2 Homo sapiens X99897 (sr:human) (de:h.sapeins mrna for p/q-type calcium channel alpha1 subunit.) (nt:p/q-type; cacn11a4) 25470928_c1_149 6534 23105 1182 393 899 −91 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete geneome; segment 44/162.) (nt:rv0975c, (mtv044.03c), len: 382.fade13, probable) 2995840_c1_151 6535 23106 1665 554 18454640_c1_156 6536 23107 426 141 99 −4 Enterobacter CONTIG438 GTC ORF with score 409 to: cloacae (ai:7501734882) (or:Klebsiella pneumoniae) 32214403_c1_159 6537 23108 639 212 746 −74 Pseudomonas Q04628 (de:hypothetical 16.7 kd protein in hemn-anr aeruginosa intergenic region (orf x)) 36589837_c1_160 6538 23109 726 241 148 −11 Enterobacter CONTIG510 GTC ORF with score 237 to: cloacae (ai:7501732413) (or:Klebsiella pneumoniae) 564166_c1_161 6539 23110 747 248 99 −4 Klebsiella Contig294A GTC ORF with score 237 to: pneumoniae (ai:7000845050) (or:Enterobacter cloacae) 31928806_c1_162 6540 23111 450 149 120 −6 equine D88685 (sr:equine herpesvirus 1 (strain:hha) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for tegument EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 29727332_c1_167 6541 23112 1302 433 36034467_c1_168 6542 23113 528 175 91 −3 Enterobacter CONTIG456 GTC ORF with score 91 to: (ai:7000778717) cloacae (or:Pseudomonas aeruginosa) 16511317_c1_169 6543 23114 1218 405

TABLE 2 NT AA SEQ SEQ NT AA Orf Name ID ID Length Length Score Exponent Organism Accession Description 2504776_c2_183 6544 23115 270 89 13160331_c2_186 6545 23116 915 304 277 −23 Escherichia coli X04487 (de:e.coli dnazx gene for dna polymerase iii subunits gamma (dnaz) and tau (dnax).) 16119556_c2_187 6546 23117 513 170 100 −3 Haemophilus P43746 (ec:2.7.7.7) (de:dna polymerase iii subunits influenzae gamma and tau,) 35182331_c2_188 6547 23118 372 123 386 −36 Escherichia coli P17577 (de:hypothetical 12.0 kd protein in dnax-recr intergenic region) 31302030_c2_189 6548 23119 675 224 661 −65 Escherichia coli P12727 (de:recombination protein recr) 36230318_c2_192 6549 23120 1038 345 99 −5 Acinetobacter CONTIG218 GTC ORF with score 99 to: (ai:7000778741) baumannii C (or:Pseudomonas aeruginosa) 24730041_c2_200 6550 23121 966 321 291 −25 Enterobacter CONTIG406 GTC ORF with score 281 to: cloacae (ai:7000778749) (or:Pseudomonas aeruginosa) 26219768_c2_205 6551 23112 624 207 119 −4 Saccharomyces P14922 (sr:,baker's yeast) (de:glucose repression cerevisiae mediator protein) 32291316_c2_206 6552 23123 510 169 115 −7 Enterobacter CONTIG362 GTC ORF with score 358 to: cloacae (ai:7501759418) (or:Klebsiella pneumoniae) 25415786_c2_208 6553 23124 1740 579 114 −5 Enterobacter CONTIG362 GTC ORF with score 219 to: cloacae (ai:7501759421) (or:Klebsiella pneumoniae) 26673805_c3_220 6554 23125 456 151 672 −66 Escherichia coli U77087 (de:escherichia coli plasmid r831b organomercury resistance (omr)locus: mer operon regulatory protein (merr) and organomercuriallyase (merb) genes, complete cds.) (nt:similar to genbank accession number m24940: mer) 15789838_c3_221 6555 23126 459 152 10360057_c3_243 6556 23127 942 313 192 −15 Escherichia coli P27307 (de:hypothetical 26.6 kd protein in udha-trma intergenic region (orfa)) 33785842_c3_250 6557 23128 564 187 90 −2 Gallus gallus U37274 (sr:chicken) (de:gallus gallus winged helix domesticus protein cwh-3 mrna, complete cds.) (nt:winged helix transcription factor) 33864658_c3_256 6558 23129 1899 632 185 −11 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 33699032_c3_259 6559 23130 1266 421 6730380_f1_9 6560 23131 1305 434 34660458_f1_10 6561 23132 525 174 4423441_f1_11 6562 23133 372 123 10442883_f1_15 6563 23134 1644 547 104 −5 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) 3239780_f1_16 6564 23135 420 139 113 −6 Schizo- Z95620 (sr:fission yeast) (de:s.pombe chromosome ii saccharomyces cosmid c3d6.) (nt:spbc3d6.14c, unknown; pombe partial; serine rich,) 34462965_f1_24 6565 23136 993 330 116 −5 mice|C57BL/ U46463 (sr:house mouse) (de:mus musculus 6xCBA/CaJ glutamine repeat protein-1 mrna, complete hybrid cds.) (nt:grp-1) 2630387_f1_29 6566 23137 888 295 721 −71 Aquifex aeolicus G70456 4353776_f1_38 6567 23138 807 268 143 −9 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 4353776_f1_47 6568 23139 807 268 143 −9 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 30665906_f1_50 6569 23140 3741 1246 939 −94 Chlorobium U77780 (de:chlorobium limicola strain dsm 249 limicola f.sp. endogenous plasmid pc11, complete genomic thiosulfatophilum sequence.) (nt:orf2.1; putative; 51.9 kda, iep 6.8, ntp binding) 10011380_f1_53 6570 23141 630 209 25962782_f1_56 6571 23142 288 95 95 −5 Brassica napus L47351 (sr:brassica napus (strain westar, sub_species olifera) (clone: st) (de:brassica napus (clone sta 39-3) arabinogalactan protein mrna, complete cds.) 16815716_f1_57 6572 34143 1695 564 10833193_f1_58 6573 23144 1440 479 14558341_f1_64 6574 23145 534 177 261 −23 Enterobacter CONTIG451 GTC ORF with score to: cloacae (ai:7501738865) (or:Klebsiella pneumoniae) 7235326_f1_66 6575 23146 1065 354 164 −12 Klebsiella Contig378A GTC ORF with score 556 to: pneumoniae (ai:7000829900) (or:Enterobacter cloacae) 12239041_f1_68 6576 23147 1647 548 348 −29 Cyanobacterium S75940 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 26369457_f1_74 6577 23148 1047 348 332 −30 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 29480042_f1_76 6578 23149 3273 1090 1516 −155 Escherichia coli P07648 (ec:3.1.11.5) (de:v gamma chain)) 2864503_f1_77 6579 23150 3810 1269 877 −203 Escherichia coli P08394 (ec:3.1.11.5) (de:beta chain)) 32557092_f1_80 6580 23151 462 153 98 −5 Klebsiella Contig550A GTC ORF with score 134 to: pneumoniae (ai:6000693762) (or:Nicotiana alata) (sr:persian tobacoo) (de:nicotiana alata 120 kda style glycoprotein (naprp5) mrna, complete cds.) (nt:style-specific protein processing features of) 26815717_f2_100 6581 23152 1794 597 119 −3 Saccharomyces P18480 (sr:,baker's yeast) (de:(transcription factor cerevisiae type4)) 7270840_f2_102 6582 23153 438 145 119 −7 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 29422656_f2_105 6583 23154 1842 613 12790831_f2_110 6584 23155 702 233 115 −4 Caenorhabditis Z77662 (de:caenorhabditis elegans cosmid f47b8, elegans complete sequence.) (nt:predicted using genefinder) 35798331_f2_122 6585 23156 1974 657 187 −12 Enterobacter CONTIG479 GTC ORF with score 273 to: cloacae (ai:7000797020) (or:Pseudomonas aeruginosa) 16917542_f2_124 6586 23157 1647 548 1205 −122 Escherichia coli P39342 (de:hypothetical 54.3 kd protein in pep-gntv intergenic region (f500)) 32322941_f2_129 6587 23158 423 140 133 −7 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 4557338_f2_131 6588 23159 1194 397 10599030_f2_133 6589 23160 423 140 129 −7 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 22782318_f2_136 6590 23161 789 262 96 −3 Enterobacter CONTIG489 GTC ORF with score 188 to: cloacae (ai:7000783196) (or:Pseudomonas aeruginosa) 12972580_f2_137 6591 23162 1032 343 152 −8 Arancus U47856 (de:arancus diadematus fibroin-4 mrna, diadematus partial cds.) 11893950_f2_141 6592 23163 579 192 4549143_f2_142 6593 23164 1176 391 16667706_f2_143 6594 23165 612 203 104 −3 Caenorhabditis P18834 (de:cuticle collagen 14) elegans 22083256_f2_144 6595 23166 909 302 155 −7 Caenorhabditis P17140 (de:collagen alpha 2(iv) chain precursor) elegans 16291680_f2_152 6596 23167 465 154 169 −12 Boreogadus saida U43200 (de:boreogadus sida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 36433156_f2_161 6597 23168 867 288 153 −11 Ralstonia P27750 (de:hypothetical protein in acoc 3′region (orf cutropha 8) (fragment)) 628540_f2_163 6598 23169 921 306 224 −17 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10242833_f2_164 6599 23170 510 169 112 −5 Klebsiella Contig471A GTC ORF with score 135 to: pneumoniae (ai:7000807844) (or:Pseudomonas aeruginosa) 35260330_f2_167 6600 23171 297 98 16119781_f2_173 6601 23172 825 274 129 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 29817205_f2_174 6602 23173 966 321 146 −7 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:,african clawed frog) 31369807_f2_178 6603 23174 543 180 95 −2 Gallus gallus D88440 (sr:gallus gallus cell_line:msb-1 cdna to domesticus mrna) (de:gallus gallus mrna for high molecular mass nuclear antigen, partial cds.) (nt:hmna) 26297633_f2_180 6604 23175 477 158 145 −9 equine D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for tegument EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 13179131_f2_182 6605 23176 927 308 176 −9 equine AF030027 (fn:very large tegument protein) (de:equine herpesvirus type 4 herpesvirus 4 strain ns80567, complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 11727017_f2_185 6606 23177 1389 462 36042033_f3_186 6607 23178 2577 858 628 −62 Klebsiella Contig460A GTC ORF with score 665 to: pneumoniae (ai:7000817667) (or:Enterobacter cloacae) 36069558_f3_187 6608 23179 558 185 125 −5 Nephila clavipes AF027972 (de:nephila clavipes flagelliform silk protein (flag) mrna, partial cds.) 25484668_f3_200 6609 23180 1350 449 17067708_f3_203 6610 23181 2031 676 101 −1 Acanthamoeba P19706 (sr:,amoeba) (de:myosin heavy chain ib castellanii (myosin heavy chain il)) 24845753_f3_204 6611 23182 1530 509 1110 −112 Escherichia coli P04995 (ec:3.1.11.1) (de:deoxyribophosphodiesterases) (drpase)) 13097911_f3_209 6612 23183 543 180 106 −3 Saimiriine Q01042 (sr:11,) (de:immediate-early protein) herpesvirus 2 7208530_f3_211 6613 23184 1380 459 1266557_f3_212 6614 23185 2028 675 115 −3 Nephial clavipes A36068 10183166_f3_214 6615 23186 813 270 142 −9 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-544000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 23572705_f3_218 6616 23187 2073 690 162 −9 Enterobacter CONTIG486 GTC ORF with score 304 to: cloacae (ai:7000797202) (or:Pseudomonas aeruginosa) 2153500_f3_221 6617 23188 957 318 12273891_f3_223 6618 23189 930 309 113 −6 Aspergillus Contig8315 GTC ORF with score 113 to: fumigatus (ai:7000779042) (or:Pseudomonas aeruginosa) 31304213_f3_228 6619 23190 942 313 127 −5 Methano- C69231 bacterium thermo- autotrophicum 4431713_f3_229 6620 23191 1656 551 104 −2 Caenorhabditis Z66494 (de:caenorhabditis elegans cosmid c34c6, elegans complete sequence.) (nt:similar to peroxisomal-like protein; cdna est) 6500030_f3_236 6621 23192 2322 773 304 −23 Bradyrhizobium P15939 (ec:2.7.3.—) (de:nodulation protein v,) japonicum 26276411_f3_241 6622 23193 1239 412 250 −18 silkworm S42886 (cl:unassigned collagens) (sr:, silkworm) 16667661_f3_242 6623 23194 708 235 109 −3 Stronglyo- L15365 (sr:strongylocentrotus purpuratus (library: centrotus caltech, eric davidson)) (de:sca urchin stage purpuratus specific activator protein mrna, complete cds.) 10274165_f3_247 6624 23195 963 320 128 −5 Homo sapiens P55316 (sr:,human) (de:transcription factor bf-2 (brain factor 2) (bf2) (hfk2)) 35286583_f3_250 6625 23196 741 246 22755381_f3_251 6626 23197 1095 364 131 −5 Homo sapiens AB010962 (sr:homo sapiens female uterus cdna to mrna, clone_:lambda gt11) (de:homo sapiens mrna for mifr-2, complete cds.) (nt:metalloproteinase in the female reproductive) 32711632_f2_253 6627 23198 507 168 105 −3 Pinctada fucata D86074 (sr:pinctada fucata cdna to mrna) (de:pinctada fucata mrna for insoluble protein, complete cds.) 13147001_f3_255 6628 23199 1092 363 98 −2 Homo sapiens U30829 (fn:splicing factor) (sr:human) (de:human splicing factor srp5503 (srp55) mrna, partial cds.) (nt:member of the family of sr protein pre-mrna) 35205066_f3_258 6629 23200 639 212 99 −5 Klebsiella Contig553A GTC ORF with score 99 to (ai:7000779077) pneumoniae (or:Pseudomonas aeruginosa) 32085381_f3_259 6630 23201 2376 791 660 −83 Haemophilus P45158 (cc:3.1.11.5) (de:exodeoxyribonuclease v influenzae alpha chain,) 2382075_f3_261 6631 23202 2715 904 172 −10 Klebsiella Contig546A GTC ORF with score 245 to: pneumoniae (ai:7000835646) (or:Enterobacter cloacae) 35817207_c1_266 6632 23203 1848 615 223 −15 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12758307_c1_268 6633 23204 597 198 178 −13 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 13022628_c1_270 6634 23205 987 328 103 −2 Brassica napus U59443 (sr:rape) (de:barssica napus myrosinase- binding protein mrna, complete cds.) 13917660_c1_271 6635 23206 684 227 92 −4 Aspergillus Contig9437 GTC ORF with score 92 to: (ai:7000779090) fumigatus (or:Pseudomonas aeruginosa) 32547708_c1_274 6636 23207 591 196 172 −12 Homo sapiens O00268 (sr:,human) (de:(tafii135) (tafii-130) 9978843_c1_275 6637 23208 2775 924 198 −13 Klebsiella Contig553A GTC ORF with score 198 to: pneumoniae (ai:7000779094) (or:Pseudomonas aeruginosa) 14324151_c1_277 6638 23209 561 186 206 −17 Klebsiella Contig553A GTC ORF with score 426 to: pneumoniae (ai:7000828341) (or:Enterobacter cloacae) 36540707_c1_279 6639 23210 2084 1027 258 −21 Klebsiella Contig553A GTC ORF with score 258 to: pneumoniae (ai:7000779098) (or:Pseudomonas aeruginosa) 5214663_c1_281 6640 23211 1437 478 137 −5 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes-like match virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf73 homolog) 32672316_c1_282 6641 23212 2163 720 95 −1 Drosophila AJ001514 (sr:fruit fly) (de:drosophila melanogaster melanogaster mrna for dring protein.) 3385811_c1_283 6642 23213 1149 482 135 −8 Enterobacter CONTIG383 GTC ORF with score 231 to: cloacae (ai:7000797020) (or:Pseudomonas aeruginosa) 21562956_c1_285 6643 23214 1482 493 1396 −143 Escherichia coli P37308 (de:low-affinity inorganic phosphate transporter 1) 11772917_c1_287 6644 23215 660 219 180 −12 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus 6xCBA/CaJ plenty-of-prolines-101 mrna, complete cds.) hybrid (nt:binds to several sh3 domain containing proteins) 16539515_c1_288 6645 23216 516 171 94 −3 Aspergillus v1x1ep68.x GTC ORF with score 192 to: fumigatus (ai:380588) (or:Homo sapiens) (sr:homo sapiens (tissue library: lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 14303415_c1_291 6646 23217 2376 791 107 −2 Mediterranean Y08913 (sr:mediterranean fruit fly) (de:c.capitata fruit fly mrna for chorion protein s18.) 16267567_c1_295 6647 23218 411 136 107 −6 Klebsiella Contig541A GTC ORF with score 138 to: pneumoniae (ai:1500696584) (or:Equine herpesvirus 1) (sr:equine herpesvirus 1 (strain:hh1) dna) (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 16507307_c1_296 6648 23219 1539 512 12770405_c1_300 6649 23220 1308 435 13127031_c1_301 6650 23221 933 310 162 −9 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol n2) elegans (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 14943816_c1_303 6651 23222 915 304 102 −2 Actinomyces S20590 (ec:3.2.1.18) viscosus 6417627_c1_304 6652 23223 630 209 114 −5 Aspergillus Contig8029 GTC ORF with score 310 to: fumigatus (or:Plasmodium yoelii) (de:plasmodium yoelii yoelii erythrocyte binding protein (maeb1) gene, complete cds.) (nt:maeb1) 16300032_c1_308 6653 23224 429 142 178 −14 Klebsiella Contig471A GTC ORF with score 178 to: pneumoniae (ai:7000779127) (or:Pseudomonas aeruginosa) 35724025_c1_309 6654 23225 189 62 157 −12 Klebsiella Contig471A GTC ORF with score 178 to: pneumoniae (ai:7000779127) (or:Pseudomonas aeruginosa) 10626412_c1_313 6655 23226 1119 372 116 −5 Klebsiella Contig542A GTC ORF with score 306 to: pneumoniae (ai:7000819556) (or:Enterobacter cloacae) 6417627_c1_314 6656 23227 630 209 112 −6 longfin squid S56117 (sr:,longfin squid) 14930306_c1_320 6657 23228 1167 388 92 −1 Bos primigenius D82986 (fn:dna binding protein) (sr:bos taurus taurus (strain:japanese black cattle) dna, clone_lib:japanes) (de:bovine dna for ccaat/enhancer-binding delta protein, complete cds.) 22712716_c1_321 6658 23229 1074 357 235 −20 Klebsiella Contig177A GTC ORF with score 729 to: pneumoniae (ai:7000815458) (or:Enterobacter cloacae) 31378761_c1_327 6659 23230 783 260 14941251_c1_328 6660 23231 558 185 140 −8 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 29937706_c1_330 6661 23232 444 147 112 −5 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 12758266_c1_333 6662 23233 1791 596 755 −76 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 155/162.) (nt:rv3692, (mtv025.040), len: 358, probable regulatory) 2635951_c1_339 6663 23234 861 286 34070906_c1_340 6664 23235 984 327 332 −30 Escherichia coli P03807 (de:35.6 kd protein in tpx-fnr intergenic region) 35282257_c1_342 6665 23236 456 151 119 −6 Homo sapiens A47234 (cl:unassigned homeobox proteins:homeobox homology) (sr:, man) 13067626_c2_350 6666 23237 3702 1233 732 −69 Rhodobacter AF010496 (de:rhodobacter capsulatus strain sb1003, capsulatus partial genome.) 12364158_c2_351 6667 23238 1149 382 249 −19 Klebsiella Contig553A GTC ORF with score 587 to: pneumoniae (ai:7000828365) (or:Enterobacter cloacae) 22862791_c2_352 6668 23239 651 216 231 −19 Klebsiella Contig553A GTC ORF with score 587 to: pneumoniae (ai:7000828365) (or:Enterobacter cloacae) 12379083_c2_355 6669 23240 411 136 110 −6 Schizo- D89103 (sr:schizosccharomyces pombe (strain:pr745) saccharomyces cdna to mrna) (de:schizosaccharomyces pombe pombe mrna, partial cds, clone: sy 0143.) (nt:unnamed protein product) 16536408_c2_356 6670 23241 435 144 125 −8 Klebsiella Contig553A GTC ORF with score 125 to: pneumoniae (ai:7000779175) (or:Pseudomonas aeruginosa) 33870166_c2_362 6671 23242 423 140 134 −9 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin domesticus gene coding for phosvitin, exons 23 and 24.) 35814386_c2_368 6672 23243 294 97 100 −5 Gallus gallus P15340 (sr:,chicken) (de:sperm histone (protamine) domesticus (galline)) 24038257_c2_372 6673 23244 834 277 345 −31 Escherichia coli P76241 (de:hypothetical transcriptional regulator in gapa-rnd intergenic region) 22707281_c2_373 6674 23245 1260 419 370 −34 Pseudomonas P14285 (de:chromate transport protein) aeruginosa 3394458_c2_374 6675 23246 1731 576 126 −7 Pyrococcus AP000002 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 287001-54000 nt. position(2/7).) (nt:motif=prokaryotic membrane lipoprotein lipid) 20985215_c2_377 6676 23247 2373 790 122 −3 Pneumocystis AF043102 (de:pneumocystis carinii surface glycoprotein carinii a (gpa) mrna, complete cds.) 30355143_c2_378 6677 23248 483 160 95 −3 Klebsiella Contig259A GTC ORF with score 95 to: (ai:7000779197) pneumoniae (or:Pseudomonas aeruginosa) 25678907_c2_381 6678 23249 807 268 102 −2 Pseudo- A48948 (cl:trefoil homology:zp domain homology) pleuronectes (sr:, winter flounder) americanus 32661433_c2_386 6679 23250 2469 822 3229708_c2_394 6680 23251 1782 593 22109418_c2_396 6681 23252 1923 640 3080 −9999 Pseudomonas D86947 (fn:chemotactic responses toward amino aeruginosa acids) (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa gene for chemotactic transducer, complete cds.) 11033283_c2_397 6682 23253 606 201 105 −3 Oryctolagus U46069 (sr:european rabbit) (de:oryctolagus cuniculus cuniculus fertilin alpha subunit mrna, complete cds.) (nt:sperm surface protein with metalloproteinase and) 15902002_c2_401 6683 23254 1029 342 121 −4 Homo sapiens AF026402 (sr:human) (de:homo sapiens u5 snrnp 100 kd protein mrna, complete cds.) (nt:dead-box, rs domain; prp28p homolog; putative rna) 15096917_c2_402 6684 23255 1992 663 3079 −9999 Pseudomonas D86947 (fn:chemotactic responses toward amino aeruginosa acids) (sr:pseudomonas aeruginosa (strain:pao1) dna) (de:pseudomonas aeruginosa gene for chemotactic transducer, complete cds.) 32129417_c2_403 6685 23256 1212 403 314 −28 Mycobacterium AF061562 (fn:involved in phosphatidylinositol tuberculosis dimannoside) (de:mycobacterium tuberculosis alpha-d-mannose- alpha(1-6)phosphatidylmyo- inositol monomannoside transferase (mtfb) gene, complete cds.) (nt:mtfb; mannosyltransferase) 14175791_c2_404 6686 23257 1521 506 213 −15 Archaeoglobus G69528 fulgidus 24615676_c2_407 6687 23258 435 144 457 −43 Pseudomonas U46125 (de:pseudomonas mevalonii heteromeric mevalonii transcriptional activator mvatp16 subunit (p16) gene, partial cds.) (nt:p16 is one of two unique subunits that make up) 1345666_c2_410 6688 23259 1137 378 495 −47 Klebsiella Contig483A GTC ORF with score 495 to: pneumoniae (ai:7000779229) (or:Pseudomonas aeruginosa) 16899130_c2_411 6689 23260 915 304 206 −17 Cyanobacterium S74573 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 29566580_c2_412 6690 23261 801 266 250 −21 Cyanobacterium S75694 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 35417041_c2_413 6691 23262 1143 380 123 −4 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 15728926_c2_415 6692 23263 1482 493 15116592_c2_417 6693 23264 1707 568 201 −12 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus plenty- 6xCBA/CaJ of-prolines-101 mrna, complete cds.) hybrid (nt:binds to several sh3 domain containing proteins) 12771080_c2_423 6694 23265 1611 536 1305 −133 Escherichia coli P21599 (ec:2.7.1.40) (de:pyruvate kinase ii, (pk-2)) 16067083_c2_424 6695 23266 1362 453 605 −59 Rhizobium sp. P55615 (sr:ngr234,) (de:putative transposase y4pf/y4sb) 12896008_c3_425 6696 23267 1311 436 669 −66 Rhodobacter AF010496 (dr:rhodobacter capsulatus sb1003, capsulatus partial genome.) 12972817_c3_426 6697 23268 579 192 139 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34457792_c3_428 6698 23269 717 238 135 −6 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib;pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 16886342_c3_433 6699 23270 483 160 162 −12 Klebsiella Contig553A GTC ORF with score 162 to: pneumoniae (ai:7000779252) (or:Pseudomonas aeruginosa) 24728831_c3_435 6700 23271 762 253 174 −13 Klebsiella Contig553A GTC ORF with score 353 to: pneumoniae (ai:7000828304) (or:Enterobacter cloacae) 12761681_c3_442 6701 23272 657 218 98 −2 Caenorhabditis AF056579 (de:caenorhabditis elegans strain n2 high elegans mobility group protein i beta(hmg-i-beta) mrna, complete cds.) 36063433_c3_447 6702 23273 411 136 129 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor gene, complete cds.) (nt:cleaved of polyprotein at conserved spacers r or) 16532332_c3_448 6703 23274 447 148 137 −8 human U92288 (fn:helicase, helicase-primase complex) herpesvirus type 6 (de:human herpesvirus 6 serotype to putative HHV-6 major immediate-early genes.) (nt:similar to hhv6a u86, region ie-b) 15730308_c3_449 6704 23275 483 160 153 −10 Epstein-Barr virus P03181 (sr:b95-8, human herpesvirus 4) (de:hypothetical bhlf1 protein) 13179067_c3_454 6705 23276 447 148 100 −4 Orf virus D34768 34614665_c3_455 6706 23277 456 151 107 −6 Klebsiella Contig420A GTC ORF with score 107 to: pneumoniae (ai:7000779274) (or:Pseudomonas aeruginosa) 24744381_c3_456 6707 23278 396 131 106 −6 Klebsiella Contig557A GTC ORF with score 173 to: pneumoniae (ai:7000842976) (or:Enterobacter cloacae) 11724130_c3_460 6708 23279 270 89 97 −4 Beta vulgaris S51939 (sr:, beet) (ec:3.2.1.14) 12921916_c3_463 6709 23280 1806 601 101 −4 Saccharomyces S66936 (mp:15r) cerevisiae 29817187_c3_464 6710 23281 471 156 134 −9 Enterobacter CONTIG482 GTC ORF with score 324 to: cloacae (ai:7501741983) (or:Klebsiella pneumoniae) 16276061_c3_469 6711 23282 1218 405 23471062_c3_470 6712 23283 525 174 23632687_c3_471 6713 23284 858 285 170 −10 Eubacterium Y17872 (de:eubacterium acidaminophilum orfs, orfr, acidaminophilum orfx, grdg and grdf genes.) (nt:orfr) 29947558_c3_475 6714 23285 1329 442 143 −6 Herpes simplex AF015297 (de:human herpesvirus 6 (strain virus uganda-1102) ie2hom mrna, complete cds.) (type 6/strain (nt:similar to the immediate-early 2 protein Uganda-1102) of human) 24400075_c3_488 6715 23286 300 99 10667557_c3_492 6716 23287 1911 636 1669 −172 Pseudomonas D86947 (sr:pseudomonas aeruginosa (strain:pao1) aeruginosa dna) (de:pseudomonas aeruginosa gene for chemotactic transducer, complete cds.) (nt:orf1) 24417788_c3_493 6717 23288 2106 701 3099 −9999 Pseudomonas D50642 (sr:pseudomonas aeruginosa (strain:pao1) aeruginosa dna) (de:pseudomonas aeruginosa pcta gene for transducer, complete cds.) (nt:chemotaxis system) 6527030_c3_501 6718 23289 972 323 147 −8 Mycobacterium Z80226 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 36/162.) (nt:rv0784, (mtc369.28), len: 228; unknown, some) 24808158_c3_513 6719 23290 567 188 111 −3 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early protein pseudorabies ie175) virus PRV 11197767_c3_514 6720 23291 1641 546 22113531_c3_519 6721 23292 2451 816 493 −46 Cyanobacterium S75346 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 12933507_c3_523 6722 23293 780 259 111 −4 Streptomyces P20188 (de:hypothetical 44.4 kd protein in fradiae transposon tn4556) 35438506_c3_524 6723 23294 645 214 138 −7 African clawed S07498 (cl:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 4557318_f1_1 6724 23295 867 288 154 −9 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 675703_f1_2 6725 23296 309 102 123 −8 Aspergillus Contig3544 GTC ORF with score 123 to: fumigatus (ai:7000779351) (or:Pseudomonas aeruginosa) 33706581_f1_4 6726 23297 648 215 110 −6 Candida albicans CONTIG351 GTC ORF with score 110 to: 2 (ai:7000779353) (or:Pseudomonas aeruginosa) 31816568_f1_7 6727 23298 2118 705 12930338_f1_11 6728 23299 1941 646 150 −7 Oryctolagus P16230 (sr:,rabbit) (de:precursor (hcp)) cuniculus 13142932_f1_14 6729 23300 1623 540 134 −6 Klebsiella Contig545A GTC ORF with score 380 to: pneumoniae (ai:7000810971) (or:Pseudomonas aeruginosa) 11927166_f1_25 6730 23301 996 331 492 −47 Escherichia coli P33899 (de:hypothetical 17.7 kd protein in lctd-cyse intergenic region (o157b)) 13022933_f1_33 6731 23302 825 274 141 −7 Rattus norvegicus B39066 (cl:proline-rich protein) (sr:, norway rat) 35824031_f1_35 6732 23303 192 63 10636332_f1_36 6733 23304 714 237 121 −5 Herpesvirus U23857 (fn:binds to orip to permit replication of the) papio (de:herpesvirus papio brrf2 homolog gene, partial cds, ebnal, bkrf2homolog and bkrf3 homolog genes, complete cds, and bkrf4 homolog gene, partial cds.) (nt:similar to ebnal of epstein-barr v . . . 21735141_f1_37 6734 23305 1515 504 29817712_f1_47 6735 23306 423 140 235 −20 Acinetobacter CONTIG105 GTC ORF with score 235 to: baumannii C (ai:7000779396) (or:Pseudomonas aeruginosa) 21895181_f1_50 6736 23307 1182 393 146 −7 Burkholderia U41162 (sr:burkholderia cepacia strain=17616) cepacia (de:burkholdria cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 32320176_f1_51 6737 23308 1197 398 133 −5 Homo sapiens AB011108 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0536 protein, partial cds.) 22944541_f1_52 6738 23309 558 185 130 −6 Rattus norvegicus U49057 (sr:norway rat) (de:rattus norvegicus ctd- binding sr-like protein ra9 mrna, complete cds.) (nt:ctd-binding sr-like protein) 35429756_f1_53 6739 23310 1413 470 954 −96 Escherichia coli P17802 (ec:3.2.2.—) (de:a/g-specific adenine glycosylase,) 17035457_f1_55 6740 23311 765 254 154 −8 Oryctolagus P27884 (sr:,rabbit) (de:brain calcium channel bi-2 cuniculus protein) 6348950_f1_56 6741 23312 1299 432 439 −41 Salmonella AF000001 (de:salmonella typhi pilus-tip adhesin pilv enterica (pilv) and site-specific recombinase rci (rci) serovar Typhi genes, complete cds.) (nt:site-specific recombinase) 14503403_f1_64 6742 23313 222 73 22083157_f1_65 6743 23314 198 65 16585381_f1_68 6744 23315 546 181 187 −15 Klebsiella Contig520A GTC ORF with score 195 to: pneumoniae (ai:7000786818) (or:Pseudomonas aeruginosa) 30564141_f1_69 6745 23316 960 319 516 −49 Pseudomonas AF012537 (de:pseudomonas aeruginosa acetyl-coa aeruginosa synthetase gene, partial cds; andarginine and ornithine binding protein (aotj), membrane protein(aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), and argr (argr) genes, complete cds.) ( . . . 33726415_f1_70 6746 23317 1446 481 535 −51 Agrobacterium P35115 (de:octopine transport system permease tumefaciens (TI protein occm) PLASMID PTIBO542) 12151057_f1_75 6747 23318 1667 558 107 −2 Molluscum L10127 (sr:molluscum contagiosum virus type 1 dna) contagiosum virus (de:molluscum contagiosum virus type 1 orf1 subtype 1 and orf2 dna.) (nt:orf17) 6823881_f1_76 6748 23319 1488 495 1983 −205 Pseudomonas AF047693 (de:pseudomonas aeruginosa multidrug aeruginosa resistance efflux pump homolog pmra (pmra) and multidrug resistance efflux pump homolog pmrb(pmrb) genes, complete cds.) (nt:membrane fusion protein, similar to emra of) 25683256_f1_77 6749 23320 1485 494 122 −6 Asperillus Contig7321 GTC ORF with score 122 to: fumigatus (ai:7000779426) (or:Pseudomonas aeruginosa) 4713556_f1_78 6750 23321 1380 459 1053 −106 Escherichia coli P39347 (de:prophage p4 integrase (int(p4))) 5197151_f1_83 6751 23322 1062 353 1409 −144 Burkholderia AF064070 (de:burkholderia pseudomallei putative pseudomallei dihydroorotase (pyrc) gene, partial cds; putative 1-acyl-sn-glycerol-3- phosphateacyltransferase (plsc), putative diadenosine tetraphosphatase(apah), complete cds; type ii o-antigen biosynthesis g . . . 26833458_f1_86 6752 23323 1443 480 649 −63 Burkholderia AF064070 (de:burkholderia pseudomallei putative pseudomallei dihydroorotase (pyrc) gene, partial cds; putative 1-acyl-sn-glycerol-3- phosphateacyltransferase (plsc), putative diadenosine tetraphosphatase(apah), complete cds; type ii o-antigen biosynthesis g . . . 14973781_f1_90 6753 23324 564 187 100 −2 infectious bovine Z78205 (de:bovine herpesvirus type 1 u122-35 rhinotracheitis genes.) (nt:very large tegument protein) virus 31300966_f1_92 6754 23325 777 258 97 −2 mice|C57BL/ S19560 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/CaJ hybrid 5878757_f1_93 6755 23326 1191 396 101 −2 mice|C57BL/ S04336 (cl:unassigned ribonucleoprotein repeat- 6xCBA/CaJ containing proteins:ribonucleoprotein repeat homology) (sr:, house mouse) 26377326_f1_95 6756 23327 1509 502 1192 −121 Rhodobacter S19739 capsulatus 12993956_f1_97 6757 23328 1500 499 2441 −253 Pseudomonas P18275 (de:arginine/ornithine antiporter) aeruginosa 29862675_f1_98 6758 23329 1278 425 2185 −226 Pseudomonas S02138 (ec:3.5.3.6) aeruginosa 16895716_f1_107 6759 23330 1104 367 147 −10 Klebsiella Contig455A GTC ORF with score 480 to: pneumoniae (ai:7000837179) (or:Enterobacter cloacae) 26189681_f1_110 6760 23331 993 330 385 −35 Mycobacterium AJ000188 (fn:unknown regulatory protein.) tuberculosis (de:mycobacterium tuberculosis oxys gene, complete cds.) (nt:oxys. probable regulatory protein. contains ps00044) 17064162_f1_111 6761 23332 858 285 417 −39 Haemophilus P44449 (de:fdhd protein) influenzae 4191691_f1_114 6762 23333 315 104 134 −9 Klebsiella Contig549A GTC ORF with score 95 to: pneumoniae (ai:7500985756) (or:Plasmodium chabaudi) (de:plasmodium chabaudi circumsporozoite protein (cs) gene, partial cds.) 22444181_f1_116 6763 23334 1164 387 210 −15 Arabidopsis P27483 (sr:,mouse-car cress) (de:glycine-rich cell thaliana wall structural protein precursor) 30710952_f1_117 6764 23335 732 243 173 −13 Mycobacterium Z97193 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 85/162.) (nt:rv1885c, (mtcy180.33), len: 199. some similarity) 16487780_f1_124 6765 23336 1359 452 145 −7 Enterobacter CONTIG509 GTC ORF with score 750 to: cloacae (ai:7000763079) (or:Pseudomonas aeruginosa) 26832706_f2_130 6766 23337 306 101 105 −5 Caenorhabditis Z67738 (de:caenorhabditis elegans cosmid elegans w03g11, complete sequence.) (nt:similar to cuticle collagen; cdna est cemsc07f) 6816287_f2_132 6767 23338 2856 951 427 −37 Pseudomonas AF051690 (de:pseudomonas aeruginosa iron-uptake aeruginosa factor (piuc), hydroxamate- typeferrisiderophore receptor (piua), and iron-uptake factor (piub)genes, complete cds.) (nt:niua) 15712700_f2_143 6768 23339 1593 530 22926336_f2_148 6769 23340 1782 593 32626656_f2_149 6770 23341 1530 509 824 −82 Streptomyces AL023496 (de:streptomyces coelicolor cosmid 1a6.) coelicolor (nt:sc1a6.06, possible transmembrane transporter, :) 36042033_f2_153 6771 23342 903 300 200 −16 Enterobacter CONTIG415 GTC ORF with score 204 to: cloacae (ai:7000776594) (or:Pseudomonas aeruginosa) 10253313_f2_155 6772 23343 336 111 101 −4 Schizosaccharo- AF038575 (gn:wsp1+) (fn:actin patch assembly and myces pombe localization) (sr:fission yeast) (de:schizosaccharomyces pombe wiskott- aldrich syndrome protein homolog(wsp1+) gene, complete cds, and btf3/beta-nac gene, partial sequence.) (nt:wasp homolog; wsp . . . 24719456_f2_158 6773 23344 495 164 138 −9 Escherichia coli P15041 (de:very hypothetical 17.7 kd protein in secb region) 32519503_f2_163 6774 23345 741 246 126 −7 Klebsiella Contig217A GTC ORF with score 221 to: (ai:405746) pneumoniae (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 32707341_f2_164 6775 23346 2463 820 459 −43 Escherichia coli P37690 (de:hypothetical 47.5 kd protein in secb-tdh intergenic region) 10808156_f2_166 6776 23347 603 200 300 −26 Escherichia coli P37691 (de:hypothetical 30.7 kd protein in secb-tdh intergenic region) 34505408_f2_167 6777 23348 663 220 150 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35604541_f2_170 6778 23349 1284 427 24629451_f2_171 6779 23350 882 293 267 −23 Klebsiella Contig412A GTC ORF with score 717 to: pneumoniae (ai:7000825102) (or:Enterobacter cloacae) 35647931_f2_174 6780 23351 702 233 266 −23 Klebsiella Contig412A GTC ORF with score 691 to: pneumoniae (ai:7000825105) (or:Enterobacter cloacae) 22833588_f2_175 6781 23352 1899 632 357 −32 Escherichia coli P37339 (de:hypothetical 48.6 kd protein in alpa-gabp intergenic region) 9823538_f2_176 6782 23353 2346 781 140 −6 Escherichia coli P28249 (de:asma protein precursor) 16993911_f2_177 6783 23354 549 182 93 −2 bovine Z84818 (de:bovine herpesvirus type 4 gene herpesvirus encoding gp80.) type 4 BHV-4 10395942_f2_178 6784 23355 369 122 250 −21 Haemophilus P44048 (de:hypothetical protein hi0760) influenzae 31741406_f2_179 6785 23356 1110 369 786 −78 Escherichia coli B64919 10286577_f2_182 6786 23357 369 122 13070776_f2_185 6787 23358 258 85 12581427_f2_188 6788 23359 369 122 15105257_f2_198 6789 23360 918 305 115 −4 Homo sapiens AF055376 (sr:human) (de:homo sapiens short form transcription factor c-maf (c-maf) mrna, complete cds.) (nt:b-zip transcription factor) 16019751_12_199 6790 23361 825 274 863 −86 Pseudomonas AF012537 (de:pseudomonas aeruginosa acetyl-coa aeruginosa synthetase gene, partial cds; andarginine and omithine binding protein (aotj), membrane protein(aotq), membrane protein (aotm), aoto (aoto), atpase (aotp), and argr (argr) genes, complete cds.) ( . . . 5112626_f2_201 6791 23362 702 233 485 −46 Rhizobium U66830 (fn:opine transport; permease) meliloti (de:rhizobium meliloti octopine catabolism (megaplasmid operon: occr, occq, occm, occp, occt, pRME41B SYM) occb, and occa genes. complete cds.) 35285955_f2_203 6792 23363 882 293 115 −4 black rat D88461 (sr:rattus rattus cdna to mrna) (de:rat mrna for n-wasp, complete cds.) 33306455_f2_205 6793 23364 528 175 220 −18 Escherichia coli D90796 (sr:escherichia coli (str:k12) dna, clone_:kohara lambda minise) (de:e.coli genomic dna, kohara clone #305(34.7- 35.1 min.).) (nt:orf_id:o306#1; similar to (pir accession number) 1275280_f2_206 6794 23365 1482 493 711 −70 Sphingomonas AF079317 (de:sphingomonas aromaticivorans aromaticivorans plasmid pn11, complete plasmid sequence.) (nt:putative outer membrane component efflux pump) 12971955_f2_207 6795 23366 432 143 138 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11182090_f2_209 6796 23367 411 136 96 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein discoideum sp96) 14557830_f2_210 6797 23368 1587 528 2588 −269 Pseudomonas AF047693 (de:pseudomonas aeruginosa multidrug aeruginosa resistance efflux pump homologpmra (pmra) and multidrug resistance efflux pump homolog pmrb(pmrb) genes, complete cds.) (nt:14 tms efflux pump; similar to emrb of escherichia) 29314415_f2_211 6798 23369 285 94 118 −7 Klebsiella Contig503A GTC ORF with score 118 to: pneumoniae (ai:7000779560) (or:Pseudomonas aeruginosa) 14493905_f2_214 6799 23370 1056 351 13007155_f2_218 6800 23371 405 134 117 −6 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 32556956_f2_219 6801 23372 1695 564 1186 −120 Salmonella P55254 (ec:2.7.7.24) (de:synthase) (dtdp-glucose anatum pyrophosphorylase)) 35275692_f2_221 6802 23373 1857 618 139 −5 equine AF030027 (fn:very large tegument protein) herpesvirus type 4 (de:equine herpesvirus 4 strain ns80567, EHV-4 complete genome.) (nt:counterpart of hsv-1 gene u136 and vzy gene 22) 32547131_f2_222 6803 23374 1515 504 1095 −111 Rhizobium C33586 (cl:nitrogen assimilation regulatory protein meliloti ntrc:response regulator homology:rna (megaplasmid polymerase sigma factor interaction pRME41B SYM) domain homology) 19744827_f2_223 6804 23375 1236 411 787 −78 Rhodobacter P37735 (sr:,rhodopseudomonas capsulata) (de:c4- capsulatus dicarboxylate-binding periplasmic protein precursor) 24511063_f2_224 6805 23376 648 215 191 −15 Rhodobacter X63974 (de:r capsulatus dctp gene for capsulatus c4-dicarboxylase binding protein.) 10801006_f2_229 6806 23377 1125 374 1751 −180 Pseudomonas S00032 (cl:ornithine aeruginosa carbamoyltransferase:aspartate/ornithine carbamoyltransferase homology) (ec:2.1.3.3) 29770831_f2_230 6807 23378 993 330 1576 −162 Pseudomonas P13982 (ec:2.7.2.2) (de:carbamate kinase,) aeruginosa 12593900_f2_233 6808 23379 1836 611 99 −3 Aspergillus Contig6518 GTC ORF with score 103 to: (ai:186949) fumigatus (or:Loligo pealei) (sr:,longfin squid) 3230211_f2_235 6809 23380 402 133 92 −3 Schizosaccharo- Z95620 (sr:fission yeast) (de:s.pombe chromosome myces pombe ii cosmid c3d6.) (nt:spbc3d6.14c, unknown; partial; serine rich,) 26062651_f2_237 6810 23381 783 260 466 −44 Escherichia coli P45801 (de:hypothetical 25.4 kd protein in mrca-pcka intergenic region) 12360215_f2_241 6811 23382 429 142 114 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein discoideum sp96) 12379030_f2_242 6812 23383 2391 796 1966 −205 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 126/162.) (nt:rv2900c, (mtcy274.31c), len: 779. fdhf. similar to) 16056901_f2_251 6813 23384 933 310 143 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 6307843_f2_257 6814 23385 963 320 402 −37 Pseudomonas P10183 (de:transcriptional activator protein nahr) putida 7213541_f3_263 6815 23386 1485 494 467 −44 Aspergillus Contig3544 GTC ORF with score 467 to: fumigatus (ai:7000779612) (or:Pseudomonas aeruginosa) 31285026_f3_264 6816 23387 717 238 32672707_f3_266 6817 23388 435 144 162 −11 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 34103817_f3_267 6818 23389 501 166 204 −15 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32301958_f3_271 6819 23390 1509 502 23708252_f3_272 6820 23391 642 213 325 −29 Escherichia coli P75899 (de:hypothetical transcriptional regulator in wrba-puta intergenic region) 13104183_f3_273 6821 23392 1356 451 649 −64 Klebsiella Contig554A GTC ORF with score 649 to: pneumoniae (ai:7000779622) (or:Pseudomonas aeruginosa) 13131956_f3_287 6822 23393 1488 495 741 −73 Achromobacter D42594 (cl:n-carbamyl-1-amino acid georgiopolitanum amidohydrolase) 22744467_f3_296 6823 23394 189 62 110 −7 Enterobacter CONTIG356 GTC ORF with score 110 to: cloacae (ai:7000779645) (or:Pseudomonas aeruginosa) 6730002_f3_298 6824 23395 1590 529 2086 −216 Pseudomonas P52832 (sr:,pvtomato) (ec:5.4.2.I) (de:(ec 5.4.2.1) syringae (phosphoglyceromutase) (bpg-independent pgam)) 25979155_f3_299 6825 23396 1131 376 128 −6 Streptococcus CONTIG806 GTC ORF with score 167 to: (ai:222791) pneumoniae D (or:Enterococcus faecalis) (sr:enterococcus faecalis plasmid:pyi17 dna) (de:enterococcus faecalis plasmid pyi17 genes for baca, bacb, orf3, orf4, orf5, orf6, orf7, orf8, orf9, orf10, orf11, partial cds.) 4493963_f2_302 6826 23397 1284 427 900 −90 Bartonella L37094 (fn:c-terminal protease) (de:bartonella bacilliformis bacilliformis c-terminal protease gene, complete cds.) (nt:bp 1616-1744 derived from a previously reported) 12629182_f3_304 6827 23398 1032 343 95 −4 longfin squid S56117 (sr:, longfin squid) 14065831_f3_308 6828 23399 444 147 112 −7 Clostridium Contig145H GTC ORF with score 126 to: acetobutylicum (ai:7000798128) (or:Pseudomonas aeruginosa) 23837657_f3_310 6829 23400 1251 416 30119455_f3_311 6830 23401 753 250 101 −5 Escherichia coli P37613 (de:hypothetical 14.5 kd protein in livk-livj intergenic region (o127)) 30719760_f3_312 6831 23402 273 90 32203342_f3_319 6832 23403 963 320 169 −12 Klebsiella Contig526A GTC ORF with score 169 to: pneumoniae (ai:7000779668) (or:Pseudomonas aeruginosa) 20963530_f3_320 6833 23404 555 184 122 −6 white AF020261 (sr:white sandalwood) (de:santalum album sandalwood proline rich protein mrna, complete cds.) 21603291_f3_324 6834 23405 468 155 34492000_f3_325 6835 23406 450 149 26775168_f3_326 6836 23407 528 175 239 −22 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 42/162.) (nt:rv0919, (mtcy21c12.13), len: 166. some similarity) 25478876_f3_329 6837 23408 237 78 4884708_f3_335 6838 23409 486 161 98 −3 Aspergillus Contig8509 GTC ORF with score 134 to: fumigatus (ai:4000723639) (or:Homo sapiens) (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 16039582_f3_338 6839 23410 819 272 15720438_f3_340 6840 23411 804 267 112 −6 Enterobacter CONTIG24 GTC ORF with score 147 to: cloacae (ai:7500987833) (or:Caenorhabditis elegans) (de:caenorhabditis elegans cosmid d2089, complete sequence.) (nt:contains a valine and arginine rich domain,) 20197818_f3_342 6841 23412 738 245 98 −3 Klebsiella Contig492A GTC ORF with score 98 to: pneumoniae (ai:7000779691) (or:Pseudomonas aeruginosa) 31744580_f3_343 6842 23413 1254 417 16285330_f3_347 6843 23414 1230 409 117 −3 mice|C57BL/ U76716 (sr:house mouse) (de:mus musculus 6xCBA/CaJ voltage-sensitive calcium channel alpha 1 hybrid a (ccha1 a)mrna, complete cds.) (nt:ion channel) 10057028_f3_350 6844 23415 258 85 21679076_f3_358 6845 23416 3354 1117 156 −7 Saccharomyces P53327 (sr:,baker's yeast) (de:putative helicase cerevisiae ygr271w) 4553558_f3_360 6846 23417 918 305 788 −78 Escherichia coli P37760 (ec:1.1.1.133) (de:rhamnose synthetase)) 11034668_f3_364 6847 23418 1854 617 519 −77 Rhizobium P10047 (cc:2.7.3.—) (de:c4-dicarboxylate leguminosarum transport sensor protein dctb,) 31379830_f3_367 6848 23419 312 103 91 −5 Enterobacter CONTIG504 GTC ORF with score 281 to: cloacae (ai:7501777202) (or:Klebsiella pneumoniae) 34489706_f3_371 6849 23420 1317 438 178 −13 Enterobacter CONTIG495 GTC ORF with score 178 to: cloacae (ai:7000779720) (or:Pseudomonas aeruginosa) 25861068_f3_373 6850 23421 1482 493 96 −2 Enterobacter CONTIG370 GTC ORF with score 96 to: cloacae (ai:7000779722) (or:Pseudomonas aeruginosa) 31337828_f3_379 6851 23422 1908 635 250 −18 Bacillus G69842 subtilis/Bacillus globigii 30703882_f3_381 6852 23423 915 304 118 −4 equine D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) type 1 EVH-1 (de:equine herpesvirus 1 dna for tegument protein, partial cds.) (nt:kpn i subfragment of orf24) 915708_f3_384 6853 23424 1443 480 106 −4 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 101162.) (nt:rv0171, (mtci28.11), unknown, len: 515 aa;) 34500642_f3_389 6854 23425 414 137 139 −9 Rattus norvegicus S24169 (sr:, norway rat) 10025807_f3_390 6855 23426 642 213 137 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 17001662_f3_394 6856 23427 426 141 212 −17 Arabidopsis P27483 (sr:,mouse-ear cress) (de:glycine-rich cell thaliana wall structural protein precursor) 22551016_f3_397 6857 23428 615 204 134 −6 Canis S33121 (cl:homeotic protein cdp:cut repeat familaris homology:homeobox homology) (sr:, dog) 20437712_f3_401 6858 23429 1386 461 16510431_f3_403 6859 23430 405 134 123 −7 Hemicentrotus S42731 (cl:collagen alpha 2(i) chain:fibrillar pulcherrimus collagen carboxyl-terminal homology) 31533393_c1_408 6860 23431 1320 439 763 −76 Rattus norvegicus P07896 (sr:,rat) (cc:4.2.1.17:5.3.3.8:1.1.1.35) (de:peroxisomal (peroxisomal bifunctonal enzyme) (pbe) (pbfe)) 15752283_c1_411 6861 23432 1524 507 577 −56 Pseudomonas AF052750 (de:pseudomonas putida plasmid ppgh1 putida insertion sequence is 1383 transposase (tnpa), alcohol dehydrogenase (adha), and insertion sequence is 1382 transposase (tnpa) genes. complete cds.) (nt:putative) 16600437_c1_416 6862 23433 552 183 114 −7 longfin squid S56117 (sr:, longfin squid) 36463568_c1_417 6863 23434 666 221 109 −4 Chlamydomonas S19113 reinhardtii strain UTEX 1061 13166283_c1_420 6864 23435 486 161 325 −29 Acinetobacter CONTIG179 GTC ORF with score 325 to: baumannii C (ai:7000779769) (or:Pseudomonas aeruginosa) 34611716_c1_422 6865 23436 912 303 136 −9 Enterobacter CONTIG510 GTC ORF with score 136 to: cloacae (ai:7000779771) (or:Pseudomonas aeruginosa) 33729591_c1_424 6866 23437 606 201 322 −29 Klebsiella Contig543A GTC ORF with score 322 to: pneumoniae (ai:7000779773) (or:Pseudomonas aeruginosa) 13086080_c1_428 6867 23438 1437 478 524 −50 Escherichia coli S56439 36501637_c1_431 6868 23439 558 185 133 −9 Enterobacter CONTIG496 GTC ORF with score 133 to: cloacae (ai:7000779780) (or:Pseudomonas aeruginosa) 10036543_c1_434 6869 23440 279 92 108 −6 Enterococcus CONTIG504 GTC ORF with score 108 to: faecium C (ai:7000779783) (or:Pseudomonas aeruginosa) 32505291_c1_436 6870 23441 1422 473 296 −26 Enterobacter CONTIG496 GTC ORF with score 296 to: cloacae (ai:7000779785) (or:Pseudomonas aeruginosa) 25682930_c1_437 6871 23442 1410 469 137 −5 Saimiriine Q01033 (sr:11,) (de:hypothetical gene 48 protein) herpesvirus 2 16895942_c1_439 6872 23443 198 65 29298583_c1_440 6873 23444 1026 341 196 −13 Bordetella P33445 (de:hypothetical 33.8 kd protein in fhac pertussis 3′region (orfa) 16151007_c1_457 6874 23445 1530 509 280 −24 Klebsiella Contig453A GTC ORF with score 280 to: pneumoniae (ai:7000779806) (or:Pseudomonas aeruginosa) 5992915_c1_461 6875 23446 489 162 121 −8 Klebsiella Contig503A GTC ORF with score 121 to: pneumoniae (ai:7000779810) (or:Pseudomonas aeruginosa) 33636077_c1_468 6876 23447 1773 590 566 −55 Enterobacter CONTIG431 GTC ORF with score 859 to: cloacae (ai:7501742218) (or:Klebsiella pneumoniae) 16801076_c1_470 6877 23448 816 271 132 −9 Klebsiella Contig475A GTC ORF with score 132 to: pneumoniae (ai:7000779819) (or:Pseudomonas aeruginosa) 34275943_c1_474 6878 23449 867 288 224 −19 Klebsiella Contig549A GTC ORF with score 224 to: pneumoniae (ai:7000779823) (or:Pseudomonas aeruginosa) 12605217_c1_476 6879 23450 816 271 185 -14 Klebsiella Contig484A GTC ORF with score 823 to: pneumoniae (ai:7000839429) (or:Enterobacter cloacae) 26589466_c1_477 6880 23451 324 107 93 −5 Pyrococcus AP000001 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) 30173842_c1_480 6881 23452 486 161 105 −4 Homo sapiens S16506 (sr:, man) 6900383_c1_481 6882 23453 783 260 746 −74 Bradyrhizobium P05406 (de:fixr protein) japonicum 26651892_c1_484 6883 23454 366 121 11175216_c1_494 6884 23455 243 80 109 −7 Klebsiella Contig560A GTC ORF with score 109 to: pneumoniae (ai:7000779843) (or:Pseudomonas aeruginosa) 13175916_c1_496 6885 23456 408 135 210 −17 Enterobacter CONTIG160 GTC ORF with score 396 to: cloacae (ai:7501800037) (or:Klebsiella pneumoniae) 12972577_c1_497 6886 23457 1401 466 151 −10 Klebsiella Contig526A GTC ORF with score 151 to: pneumoniae (ai:7000779846) (or:Pseudomonas aeruginosa) 9817531_c1_517 6887 23458 372 123 97 −5 Ralstonia AJ001159 (de:alcaligenes cutrophus upstream region cutropha of czc with czcn, mgtc and some orfs.) (nt:orf191) 32630306_c1_519 6888 23459 777 258 13010007_c1_537 6889 23460 618 205 230 −19 Enterobacter CONTIG471 GTC ORF with score 230 to: cloacae (ai:7000779886) (or:Pseudomonas aeruginosa) 13807942_c1_551 6890 23461 1383 460 1003 −101 Rhodobacter AF031406 (de:rhodobacter capsulatus nadph capsulatus dependent glutamate synthase small subunit homolog 838 (gltx) gene, complete cds.) (nt:gltx; glutam:2-oxoglutarate amino transferase) 34479080_c1_554 6891 23462 1581 526 1436 −147 Escherichia coli P25525 (de:cytosine permease) 13016436_c1_555 6892 23463 1374 457 92 −1 Streptomyces D85898 (sr:streptomyces thermoviolaceus thermoviolaceus (strain:opc-520) dna) (ec:3.1.1.6) (de:streptomyces thermoviolaceus dna for acetyl xylan esterase, complete cds.) 10680162_c1_558 6893 23464 594 197 114 −5 Enterobacter CONTIG382 GTC ORF with score 110 to: (ai:78818) (or:Pseudorabies virus) (cl:herpesvirus immediate-early protein ie175) 10425692_c1_559 6894 23465 444 147 119 −5 Chinese oak AF083334 (sr:chinese oak silkmoth) (de:antheraea silkmoth pernyi fibroin gene, complete cds.) 32288881_c1_566 6895 23466 966 321 125 −5 Klebsiella Contig529A GTC ORF with score 150 to: pneumoniae (ai:7000794205) (or:Pseudomonas aeruginosa) 16907332_c2_577 6896 23467 1980 659 756 −76 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 64/162.) (nt:rv 1467c, (mtv007.14c), len: 609.fade15, possible) 29885330_c2_579 6897 23468 651 216 304 −28 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 10/162.) (nt:rv0163, (mtci28.03), len: 151. unknown, but) 6503962_c2_583 6898 23469 570 189 104 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 35835293_c2_591 6899 23470 582 193 94 −2 Drosophila M15765 (sr:drosophila melanogaster (strain oregon melanogaster r) (clone: p19.) pupa cdn) (de:d.melanogaster pen repeats mrna, clone p19.) (nt:orf; putative) 32677258_c2_592 6900 23471 882 293 436 −41 Escherichia coli P45799 (de:hypothetical 21.2 kd protein in mrca-pcka intergenic region (f186)) 32660905_c2_593 6901 23472 1854 617 22088583_c2_599 6902 23473 801 266 113 −3 equine P28968 (sr:ab4p,chv-1) (de:glycoprotein x herpesvirus type 1 precursor) EVH-1 5119653_c2_602 6903 23474 468 155 172 −13 Enterobacter CONTIG495 GTC ORF with score 172 to: cloacae (ai:7000779951) (or:Pseudomonas aeruginosa) 15104781_c2_603 6904 23475 231 76 140 −9 Enterobacter CONTIG495 GTC ORF with score 140 to: cloacae (ai:7000779952) (or:Pseudomonas aeruginosa) 32604183_c2_606 6905 23476 201 66 33417518_c2_626 6906 23477 243 80 104 −6 Enterobacter CONTIG488 GTC ORF with score 104 to: cloacae (ai:7000779975) (or:Pseudomonas aeruginosa) 12619805_c2_632 6907 23478 462 153 137 −9 Aspergillus v1x1fj93.x GTC ORF with score 207 to: (ai:160722) fumigatus (or:Pseudomonas aeruginosa) 7236300_c2_639 6908 23479 195 64 25828933_c2_640 6909 23480 285 94 16408582_c2_653 6910 23481 291 96 109 −5 Gallus gallus 150694 (cl:collagen alpha 1(i) chain:fibrillar domesticus collagen carboxyl-terminal homology:von willebrand factor type c repeat homology) (sr:, chicken) 13025417_c2_654 6911 23482 420 139 152 −11 Klebsiella Contig560A GTC ORF with score 152 to: pneumoniae (ai:7000780003) (or:Pseudomonas aeruginosa) 16261705_c2_660 6912 23483 546 181 130 −7 Brassica napus U59446 (sr:rapc) (de:brassica napus myrosinase- binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein;) 35360806_c2_664 6913 23484 1116 371 406 −38 Bacillus O34565 (ec:2.4.2.—) (de:amidotransferase hish,) subtilis/Bacillus globigii 33728403_c2_665 6914 23485 264 87 99 −5 Klebsiella Contig556A GTC ORF with score 99 to: pneumoniae (ai:7000780014) (or:Pseudomonas aeruginosa) 32550628_c2_666 6915 23486 786 261 652 −64 Rhodobacter P50936 (sr:,rhodopseudomonas sphaeroides) sphaeroides (cc:5.3.1.16) (de:isomerase,) 16297666_c2_670 6916 23487 765 254 140 −6 mice|C57BL/ P02463 (sr:,mouse) (de:procollagen alpha 1(iv) 6xCBA/CaJ chain precursor) hybrid 24032961_c2_671 6917 23488 1182 393 128 −5 Canadian hard JN0689 (pn:glutenin, high-molecular-weight ax2* winter wheat chain precursor) (gn:ax2*)(cl:glutenin) (sr:, common wheat) 29773580_c2_676 6918 23489 1305 434 12367187_c2_680 6919 23490 558 185 121 −5 Saccharomyces P14922 (sr:,baker's yeast) (de:glucose repression cerevisiae mediator protein) 36152292_c2_682 6920 23491 1557 518 860 −86 Klebsiella Contig555A GTC ORF with score 865 to: pneumoniae (ai:7000819630) (or:Enterobacter cloacae) 16102041_c2_683 6921 23492 645 214 227 −19 Haemophilus P44854 (de:hypothetical protein hi0744) influenzae 14886537_c2_686 6922 23493 486 161 16970418_c2_691 6923 23494 1698 565 211 −16 Klebsiella Contig551A GTC ORF with score 211 to: pneumoniae (ai:7000780040) (or:Pseudomonas aeruginosa) 16878837_c2_693 6924 23495 1611 536 145 −14 Pseudomonas L24157 (fn:amidohydrolase) (sr:pseudomonas putida putida (library: dsm 84 genomic bank of a. morin) dna) (ec:3.5.2.2) (de:pseudomonas putida d-hydantoinase gene, complete cds.) 29566705_c2_695 6925 23496 537 178 190 −13 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 25886631_c2_696 6926 23497 1902 633 29822540_c2_697 6927 23498 216 71 146 −9 Escherichia coli P25525 (de:cytosine permease) 31772908_c2_698 6928 23499 1305 434 1741 −179 Escherichia coli P25524 (ec:3.5.4.1) (de:cytosine deaminase,) 31667816_c2_699 6929 23500 714 237 97 −3 Klebsiella Contig478A GTC ORF with score 97 to: pneumoniae (ai:7000780048) (or:Pseudomonas aeruginosa) 16970658_c2_709 6930 23501 1509 502 1060 −107 Pneumocystis U57795 (sr:pneumocystis carinii strain=rattus) carinii (de:pneumocystis carinii s- adenosylhomocysteine hydrolase (sahh) mrna, partial cds.) 23650802_c3_713 6931 23502 768 255 125 −6 Plasmid pAH4 JC2322 21932661_c3_715 6932 23503 420 139 130 −8 Klebsiella Contig560A GTC ORF with score 163 to: pneumoniae (ai:7000693920) (or:Bacillus subtilis) (fn:unknown) (de:bacillus subtilis complete genome (section 16 of 21): from 2997771 to 3213410.) 25715_c3_716 6933 23504 1101 366 119 −4 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 12347715_c3_719 6934 23505 1338 445 115 −3 Micrococcus JQ0405 luteus 15116701_c3_722 6935 23506 234 77 1259581_c3_723 6936 23507 723 240 201 −14 infectious bovine Z78205 (de:bovine herpesvirus type 1u122-35 rhinotracheitis genes.) (nt:very large tegument protein) virus 10285413_c3_725 6937 23508 906 301 295 −26 Klebsiella Contig543A GTC ORF with score 295 to: pneumoniae (ai:7000780074) (or:Pseudomonas aeruginosa) 35838916_c3_726 6938 23509 1590 529 276 −24 Klebsiella Contig543A GTC ORF with score 276 to: pneumoniae (ai:7000780075) (or:Pseudomonas aeruginosa) 16882015_c3_730 6939 23510 618 205 423 −40 Escherichia coli B65046 3259791_c3_740 6940 23511 978 325 443 −42 Enterobacter CONTIG496 GTC ORF with score 443 to: cloacae (ai:7000780089) (or:Pseudomonas aeruginosa) 13708586_c3_741 6941 23512 1113 370 447 −42 Enterobacter CONTIG496 GTC ORF with score 469 to: cloacae (ai:7501741097) (or:Klebsiella pneumoniae) 36069432_c3_747 6942 23513 2511 836 144 −7 Klebsiella Contig535A GTC ORF with score 636 to: pneumoniae (ai:7000826275) (or:Enterobacter cloacae) 22447961_c3_748 6943 23514 1320 439 196 −15 Aeromonas U56832 (de:aeromonas hydrophila fk506 binding hydrophila protein (fkpa) gene, complete cds in 3.9 kb fragment.) (nt:orfs; no significant similarity with known) 995766_c3_752 6944 23515 960 319 227 −19 Klebsiella Contig453A GTC ORF with score 227 to: pneumoniae (ai:7000780101) (or:Pseudomonas aeruginosa) 16144806_c3_763 6945 23516 702 233 108 −3 Plasmodium P08675 (sr:london,) (de:circumsporozoite protein cynomolgi precursor (cs)) 26821931_c3_764 6946 23517 1065 354 280 −25 Klebsiella Contig407A GTC ORF with score 358 to: pneumoniae (ai:7000826876) (or:Enterobacter cloacae) 7276930_c3_766 6947 23518 1542 513 232 −19 Klebsiella Contig550A GTC ORF with score 232 to: pneumoniae (ai:7000780115) (or:Pseudomonas aeruginosa) 21578526_c3_775 6948 23519 765 254 244 −21 Klebsiella Contig484A GTC ORF with score 477 to: pneumoniae (ai:7000839555) (or:Enterobacter cloacae) 33494842_c3_776 6949 23520 1047 348 355 −33 Klebsiella Contig516A GTC ORF with score 124 to: pneumoniae (de:mycobacterium smegmatis iron uptake genes, fxba (fxba) gene, partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc (fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxtf) genes. complete cds.) (nt:similar to . . . 21875666_c3_780 6950 23521 2316 771 331 −42 Legionella S61388 pneumophila 5187666_c3_787 6951 23522 1512 503 315 −28 Klebsiella Contig560A GTC ORF with score 414 to: pneumoniae (ai:7000813948) (or:Enterobacter cloacae) 15673966_c3_791 6952 23523 1272 423 26738213_c3_792 6953 23524 1848 615 133 −5 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda- virus (type 6/ 1102) ic2hom mrna, complete cds.) strain (nt:similar to the immediate-early 2 Uganda-1102) protein of human) 6767675_c3_794 6954 23525 624 207 588 −57 Anabaena sp. Q05068 (sr:pcc 7120,) (ec:4.2.1.19) (de:imidazoleglcerol-phosphate dehydratase, (igpd)) 30730283_c3_796 6955 23526 456 151 99 −3 Litomosoides U54556 (de:litomosoides sigmodontis microfilarial sigmodontis sheath proteins shp3a(shp3a) and shp3 (shp3) genes, complete cds.) (nt:structural protein; similar to shp3 genes from) 16891455_c3_798 6956 23527 936 311 883 −88 Azospirillum P26721 (de:hisf protein (cyclase)) brasilense 25836458_c3_799 6957 23528 867 288 35675166_c3_800 6958 23529 843 280 650158_c3_801 6959 23530 891 296 122 −5 Plasmodium P04922 (sr:nuri,) (de:circumsporozoite protein knowlesi precursor (cs)) 26852037_c3_805 6960 23531 735 244 156 −9 Klebsiella Contig555A GTC ORF with score 491 to: pneumoniae (ai:7000819625) (or:Enterobacter cloacae) 31305180_c3_811 6961 23532 447 148 121 −7 Klebsiella Contig555A GTC ORF with score 491 to: pneumoniae (ai:7000819625) (or:Enterobacter cloacae) 24886086_c3_814 6962 23533 189 62 33792706_c3_815 6963 23534 480 159 144 −9 human U92288 (fn:helicase, helicase-primase complex) herpesvirus type 6 (de:human herpesvirus 6 serotype b HHV-6 putative major immediate-early genes.) (nt:similar to hhv6a u86, region ie-b) 12926642_c3_821 6964 23535 261 86 235 −20 Escherichia coli S47831 34082877_c3_822 6965 23536 516 171 417 −39 Haemophilus P44853 (de:protein-export protein secb) influenzae 5867665_c3_825 6966 23537 1266 421 747 −74 Klebsiella AJ010745 (de:klebsiella pneumoniae internal dna pneumoniae fragment of transposon tn5708.) 32707041_c3_826 6967 23538 525 174 131 −9 Klebsiella Contig342A GTC ORF with score 131 to: pneumoniae (ai:7000780175) (or:Pseudomonas aeruginosa) 11072206_c3_828 6968 23539 564 187 92 −2 Candida albicans CONTIG269 GTC ORF with score 448 to: (ai:78492) 4 (or:Candida albicans) (sr:,yeast) (de:hyphally regulated protein precursor) 16931953_c3_829 6969 23540 1695 564 223 −16 Klebsiella Contig551A GTC ORF with score 450 to: pneumoniae (ai:7000776777) (or:Pseudomonas aeruginosa) 23595461_c3_830 6970 23541 1524 507 2200 −228 Pseudomonas Q59699 (ec:3.5.2.2) (de:d-hydantoinase, putida (dihydropyrimidinase) (dhpase)) 35760217_c3_831 6971 23542 1017 338 149 −7 Neisseria S75490 (sr:neisseria gonorrhoeae ms11) gonorrhoeae (de:competence region: iga=iga protease, coma=transformation competence (neisseria gonorrhoeae, ms11, genomic, 3 genes, 2664 nt).) 31461558_c3_832 6972 23543 1689 562 832 −83 Escherichia coli P25889 (de:hypothetical 45.1 kd protein in cdd-mglc intergenic region) 12970691_c3_834 6973 23544 912 303 125 −7 Aspergillus Contig7490 GTC ORF with score 100 to: (ai:200807) fumigatus (or:Mus musculus) (cl:proline-rich protein) (sr:, house mouse) 10817887_c3_836 6974 23545 471 156 117 −5 Homo sapiens AC004493 (sr:human) (de:homo sapiens chromosome 16, cosmid clone 373c8 (IanI), complete sequence.) 7164151_c3_841 6975 23546 1953 650 151 −7 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 23994418_f1_1 6976 23547 6855 2284 381 −30 Neisseria AF030941 (de:neisseria meningitidis putative meningitidis secreted protein (pspa) gene, complete cds.) (nt:amino-terminus similar to a number of secreted) 5917918_f1_4 6977 23548 1683 560 124 −4 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 14742893_f1_6 6978 23549 1284 427 35585343_f1_11 6979 23550 963 320 2448916_f1_12 6980 23551 1617 538 990 −100 Pseudomonas U62581 (de:pseudomonas aeruginosa aeruginosa phenylalanine hydroxylase gene clustertranscription activator phhr (phhr) gene, complete cds.) (nt:a member of the bacterial sigma-54 enhancer-binding) 36427266_f1_15 6981 23552 1014 337 405 −38 Haemophilus U20964 (de:haemophilus influenzae dna influenzae topoisomerase i (topa) gene, complete cds, putative pyridine nucleotide transhydrogenase beta subunit(pntb) gene, partial cds, orf2 and orf3 genes, complete cds and putative threonyl-trna synthetase (thrs) ge . . . 4566318_f1_17 6982 23553 393 130 338 −30 Escherichia coli P23884 (de:glycine cleavage system h protein) 31351631_f1_18 6983 23554 1329 442 148 −10 Klebsiella Contig550A GTC ORF with score 184 to: pneumoniae (ai:7000778497) (or:Pseudomonas aeruginosa) 36042942_f1_19 6984 23555 1656 55I 152 −10 Enterobacter CONTIG493 GTC ORF with score 153 to: cloacae (ai:7000778499) (or:Pseudomonas aeruginosa) 7159556_f1_22 6985 23556 1290 429 108 −6 Enterobacter CONTIG456 GTC ORF with score 108 to: cloacae (ai:7000780214) (or:Pseudomonas aeruginosa) 36069766_f1_23 6986 23557 957 318 151 −8 Caenorhabditis Z82268 (de:caenorhabditis elegans cosmid elegans f52b11, complete sequence.) (nt:predicted using genefinder; cdna est embl:d65629) 32058317_f1_24 6987 23558 702 233 99 −3 Klebsiella Contig217A GTC ORF with score 282 to: pneumoniae (ai:5500695239) (or:Alcelaphine herpesvirus 1) (sr:wildebeast herpesvirus) (de:alcelaphine herpesvirus 1 1-dna, complete sequence.) (nt:ort73; similar to h. saimiri and kshv orf73) 29806963_f1_28 6988 23559 1449 482 32672643_f1_29 6989 23560 1602 533 284 −24 Haemophilus P44545 (ec:3.4.—.—) (de:hflc protein,) influenzae 32660031_f1_30 6990 23561 960 319 12271037_f1_31 6991 23562 528 175 16100333_f1_34 6992 23563 786 261 313 −27 Cyanobacterium S77012 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis (cc:3.6.1.—) 26676083_f1_40 6993 23564 870 289 138 −9 Escherichia coli D90807 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #316(36.7-37.1 min.).) (nt:orf_id:o317#1; similar to (swissprot accession) 15907256_f1_41 6994 23565 1125 374 165 −9 blue mussel AF043944 (sr:blue mussel) (de:mytilus edulis nongradient byssal precursor, mrna, complete cds.) (nt:precol-ng) 15911632_f1_43 6995 23566 960 319 153 −7 Acanthamoeba AF085185 (de:acanthamoeba castellanii castellanii myosin-ia(mia) gene, complete cds.) (nt:myosin-i) 3160456_f1_45 6996 23567 474 157 811 −81 Pseudomonas U12891 (de:pseudomonas aeruginosa pao substrain aeruginosa ot684 pyoverdine genetranscriptional regulator pvds (pvds) gene, complete cds.) (nt:orf2) 29880207_f1_48 6997 23568 10023 3340 4451 −9999 Pseudomonas S53999 (cl:gramicidin s synthetase i repeat aeruginosa homology:acetate--coa ligase homology:acyl carrier protein homology) 15730131_f1_50 6998 23569 2274 757 126 −4 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 36532533_f1_53 6999 23570 198 65 22050078_f1_54 7000 23571 195 64 12589417_12_61 7001 23572 411 136 148 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11720427_f2_68 7002 23573 354 117 14645651_21_69 7003 23574 291 96 36417566_f2_75 7004 23575 603 200 122 −6 Ovis orientalis U77049 (sr:sheep) (de:ovis aries bactinecin aries 11(bac11) gene, exon 4, and complete cds.) 16301025_f2_76 7005 23576 792 263 160 −9 African clawed S07498 (c1:dermal gland protein apeg:trefoil frog homology) (sr:, african clawed frog) 2469758_f2_77 7006 23577 1131 376 157 −8 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 32535215_f2_78 7007 23578 336 111 94 −3 Aspergillus niger S63587 9883407_f2_86 7008 23579 594 197 96 −2 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 13007082_f2_87 7009 23580 2910 969 3057 −9999 Cyanobacterium S76257 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 34645325_f2_90 7010 23581 1428 475 1595 −164 Streptomyces AL031184 (de:streptomyces coelicolor cosmid 2a11.) coelicolor (nt:sc2a11.03c, sdaa, probable 1-serine dehydratase,) 16134662_f2_91 701I 23582 1125 374 793 −79 Pisum sativum S56661 (sr:, garden pca) (cc:2.1.2.10) 31511463_f2_94 7012 23583 630 209 115 −4 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid t28f2.) (nt:similar to cuticular collagen) 29969832_f2_98 7013 23584 1029 342 125 −6 Chlamydomonas S19114 reinhardtii strain UTEX 1061 14572942_f2_103 7014 23585 1251 416 14976080_f2_105 7015 23586 873 290 96 −2 Plasmodium P08674 (sr:gombak,) (de:circumsporozoite protein cynomolgi precursor (cs)) 6273956_f2_109 7016 23587 198 65 29948805_f2_110 7017 23588 1929 642 183 −13 Klebsiella D84271 (sr:klebsiella oxytoca (strain:hy-1) dna) (de:klebsiella oxytoca fdt-1, 2 and 3 genes for fusaric acid detoxification proteins, complete cds.) (nt:fdt gene operon) 31539515_f2_111 7018 23589 1200 399 382 −35 Escherichia coli D90807 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #316(36.7-7.1 min.).) (nt:orf_id:o316#23; similar to (swissprot accession) 22867891_f2_113 7019 23590 930 309 1292 −132 Pseudomonas U12891 (de:pseudomonas aeruginosa pao substrain aeruginosa ot684 pyoverdine genetranscriptional regulator pvds (pvds) gene, complete cds.) (nt:orf1) 35557090_f2_114 7020 23591 1221 406 22942711_f2_116 7021 23592 885 294 1201 −122 Pseudomonas U12891 (de:pseudomonas aeruginosa pao substrain aeruginosa ot684 pyoverdine genetranscriptional regulator pvds (pvds) gene, complete cds.) (nt:orf4) 15666287_f2_117 7022 23593 354 117 310 −28 Pseudomonas U12891 (de:pseudomonas aeruginosa pao substrain aeruginosa ot684 pyoverdine genetranscriptional regulator pvds (pvds) gene, complete cds.) (nt:orf5; open reading frame required for pyoverdine) 10395657_f2_125 7023 23594 741 246 108 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein discoideum sp96) 14338581_f2_135 7024 23595 402 133 125 −8 Klebsiella Contig554A GTC ORF with score 125 to: pneumoniae (ai:7000780327) (or:Pseudomonas aeruginosa) 15104163_f2_140 7025 23596 3456 1151 1470 −149 Pseudomonas S53999 (cl:gramicidin s synthetase i repeat aeruginosa homology:acetate--coa ligase homology:acyl carrier protein homology) 36506401_f2_141 7026 23597 249 82 10566406_f3_145 7027 23598 1524 507 191 −12 Dictyostelium P35085 (sr:,slime mold) (de:calcium binding discoideum protein) 16617086_f3_147 7028 23599 483 160 117 −6 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 12320436_f3_149 7029 23600 465 154 100 −4 Aspergillus Contig8591 GTC ORF with score 273 to: (ai:405746) fumigatus (or:Mus sp.) (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 25391066_f3_152 7030 23601 630 209 36192930_f3_158 7031 23602 642 213 137 −7 Nephila clavipes A36068 22136666_f3_161 7032 23603 2235 744 347 −42 Erwinia AF011334 (de:erwinia chrysanthemi ferric chrysanthemi enterobactin esterase (fcs) gene, complete cds.) 7156451_f3_162 7033 23604 1557 518 154 −8 Plasmodium vivax U08977 (de:plasmodium vivax isolate ch-3 circumsporozoite protein gene, partial cds.) 36192556_f3_164 7034 23605 1149 382 160 −9 Caenorhabditis AF022985 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid t15b7.) (nt:similar to collagen) 30573251_f3_169 7035 23606 393 130 109 −5 Acanthamoeba P19706 (sr:,amoeba) (de:myosin heavy chain ib castellanii (myosin heavy chain i1)) 17052031_f3_175 7036 23607 336 111 126 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursor- gene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 15719756_f3_179 7037 23608 1440 479 1602 −164 Acinetobacter AF073769 (de:acinetobacter radioresistens serine radioresistens hydroxymethyltransferase (glya)gene, complete cds.) 33835006_f3_185 7038 23609 534 177 135 −9 Pseudomonas S29309 aeruginosa 32708142_f3_191 7039 23610 939 312 143 −6 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia castellanii (mia) gene, complete cds.) (nt:myosin-i) 3226416_f3_193 7040 23611 426 141 103 −5 Aspergillus Contig7369 GTC ORF with score 132 to: (ai:367998) fumigatus (or:Homo sapiens) (sr:human) (de:h.sapiens (ier47) muc5ac mrna for mucin (partial).) 34503955_f3_194 7041 23612 888 295 178 −11 Mycobacterium AL022120 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 160/162.) (nt:rv3876, (mtv027.11), len: 666. unknown, n-terminus) 12755381_f3_195 7042 23613 2187 728 131 −5 no gb taxonomy P36295 (sr:type 1/hfem,) (de:transcriptional match regulator ie63 (vmw63) (icp27)) 30339408_f3_196 7043 23614 2412 803 481 −43 Cyanobacterium Q59998 (sr:pcc 6803,) (ec:3.6.1.—) (de:probable synechocystis cation-transporting atpase slr0798,) 26648458_f3_197 7044 23615 1518 505 136 −7 Enterococcus CONTIG108 GTC ORF with score 1137 to: faecalis (ai:7000759121) (or:Pseudomonas aeruginosa) 33864405_f3_202 7045 23616 303 100 95 −5 Escherichia coli P46478 (de:hypothetical 10.3 kd protein in argr-cafa intergenic region (f90)) 10677180_f3_207 7046 23617 492 163 129 −7 Sus scrofa 147141 (sr:, domestic pig) domestica 9869715_f3_213 7047 23618 1272 423 521 −50 Pseudomonas U12891 (de:pseudomonas aeruginosa pao substrain aeruginosa ot684 pyoverdine genetranscriptional regulator pvds (pvds) gene, complete cds.) (nt:orfs; open reading frame required for pyoverdine) 2526091_f3_214 7048 23619 1479 492 108 −3 Rhesus Epstein U93909 (sr:rhesus epstein barr virus) Barr virus (de:cercopithecine herpesvirus 15 nuclear antigen ebna-1 gene, complete cds.) 2198543_f3_215 7049 23620 1494 497 223 −17 Achromobacter A61183 georiopolitanum 17053331_f3_216 7050 23621 1263 420 112 −3 Caenorhabditis Z83107 (de:caenorhabditis elegans cosmid f32a7, elegans complete sequence.) (nt:predicted using genefinder; similar to claustrin) 12754518_f3_219 7051 23622 1299 432 149 −7 Homo sapiens X13783 (sr:human) (de:human mrna for alpha-1 type 2 collagen.) 16300708_f3_220 7052 23623 831 276 151 −8 Plasmodium P08672 (sr:bcrok,) (de:circumsporozoite protein cynomolgi precursor (cs)) 15714456_f3_225 7053 23624 324 107 97 −4 Aspergillus Contig7924 GTC ORF with score 294 to: fumigatus (ai:1500692508) (or:Boreogadus saida) (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 36438327_f3_226 7054 23625 357 118 98 −5 Trypanosoma U32346 (de:trypanosoma cruzi mucin-like protein cruzi (muc.ca-2) gene, complete cds.) (nt:mucin-like protein; method: conceptual translation) 10391031_c1_240 7055 23626 1212 403 96 −2 Lactobacillus Y12813 (de:bacteriophage a2 rep, xis and int casei genes.) bacteriophage A2 33854528_c1_249 7056 23627 4242 1413 369 −32 Klebsiella Contig554A GTC ORF with score 483 to: pneumoniae (ai:7000831452) (or:Enterobacter cloacae) 22786666_c1_251 7057 23628 4236 1411 165 −9 Actinoplanes S16995 teichomyceticus 34067508_c1_268 7058 23629 1485 494 33852040_c1_275 7059 23630 1275 424 22713906_c1_280 7060 23631 942 313 109 −2 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 1354156_c1_284 7061 23632 1548 515 142 −7 mice|C57BL/ C29149 (cl:proline-rich protein) (sr:, house mouse) 6xCBA/CaJ hybrid 36526081_c1_287 7062 23633 564 187 144 −10 Clostridium Contig192H GTC ORF with score 205 to: acetobutylicum (ai:4500689127) (or:Enterococcus faecalis) 677158_c1_289 7063 23634 462 153 146 −10 Enterobacter CONTIG456 GTC ORF with score 146 to: cloacae (ai:7000780481) (or:Pseudomonas aeruginosa) 24620840_c1_296 7064 23635 393 130 92 −5 Enterobacter CONTIG493 GTC ORF with score 92 to: cloacae (ai:7000780488) (or:Pseudomonas aeruginosa) 29949031_c1_298 7065 23636 1758 585 158 −9 Klebsiella Contig501A GTC ORF with score 361 to: pneumoniae (ai:7000757282) (or:Pseudomonas aeruginosa) 10047692_c1_303 7066 23637 2751 916 412 −38 Klebsiella Contig535A GTC ORF with score 636 to: pneumoniae (ai:7000826275) (or:Enterobacter cloacae) 13008443_c1_305 7067 23638 627 208 115 −5 Orf virus D34768 1980150_c1_308 7068 23639 990 329 95 −2 Mycobacterium Z81011 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 61/162.) (nt:rv1377c, (mtcy02b12.11c), len: 212. unknown.) 15714806_c1_310 7069 23640 2925 974 349 −28 Escherichia coli AF044SO1 (de:escherichia coli strain ec45 rhse accessory genetic element coreprotein gene, partial cds, and dsorf-e4, complete cds; and rhsh accessory genetic element unknown (450), core protein, and dsorf-h1genes, complete cds.) 36189792_c1_314 7070 23641 2016 671 22003532_c1_315 7071 23642 483 160 24503877_c1_318 7072 23643 1509 503 167 −9 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 16056416_c2_319 7073 23644 804 267 598 −58 Coxiella burnetii Q45968 (de:transposase for insertion sequence element is 1111a) 36411380_c2_324 7074 23645 315 104 117 −6 Streptomyces P20186 (de:hypothetical 35.5 kd protein in fradiae transposon tn4556) 14704155_c2_325 7075 23646 591 196 149 −10 Homo sapiens PN0099 (sr:, man) 16283407_c2_331 7076 23647 612 203 117 −5 Aspergillus Contig10371 GTC ORF with score 705 to: fumigatus (ai:7500733128) (or:Candida albicans) 33830032_c2_333 7077 23648 699 232 92 −2 Gallus gallus K02113 (sr:chicken) (de:gallus gallus vitellogenin domesticus gene coding for phosvitin, exons 23 and 24.) 23947660_c2_340 7078 23649 270 89 191 −15 Enterobacter CONTIG459 GTC ORF with score 118 to: (ai:99171) cloacae (or:Dictyostelium discoideum) (de:dictyostelium discoideum sp96 gene for spore coat protein sp96.) 4505416_c2_349 7079 23650 609 202 98 −5 Klebsiella Contig141A GTC ORF with score 163 to: pneumoniae (ai:7000826341) (or:Enterobacter cloacae) 16141667_c2_361 7080 23651 822 273 246 −20 Caenorhabditis AF000298 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid w03d2.) (nt:weak similarity to collagens; glycine- and) 2867628_c2_362 7081 23652 414 137 175 −11 equine AF030027 (fn:very large tegument protein) herpesvirus type 4 (de:equine herpesvirus 4 strain ns80567, EHV-4 complete genome.) (nt:counterpart of hsv-1 gene u136 and vzv gene 22) 36113562_c2_364 7082 23653 987 328 468 −44 Cyanobacterium S77111 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 12707208_c2_365 7083 23654 384 127 26291655_c2_366 7084 23655 2472 823 149 −6 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 16901706_c2_369 7085 23656 522 173 119 −5 Herpes simplex AF015297 (de:human herpesvirus 6 (strain uganda- virus (type 6/ 1102) ic2hom mrna, complete cds.) strain (nt:similar to the immediate-early 2 Uganda-1102) protein of human) 13151005_c2_373 7086 23657 591 196 91 −4 Enterobacter CONTIG474 GTC ORF with score 91 to: cloacae (ai:7000780565) (or:Pseudomonas aeruginosa) 25831591_c2_376 7087 23658 990 329 34236057_c2_383 7088 23659 1875 624 774 −177 Enterobacter CONTIG497 GTC ORF with score 1130 to: cloacae (ai:7501726099) (or:Klebsiella pneumoniae) 16895652_c2_393 7089 23660 2160 719 261 −18 Micrococcus JQ0405 luteus 33862967_c2_396 7090 23661 420 139 107 −5 Gallus gallus D88440 (sr:gallus gallus cell_line:mas-1 cdna to domesticus mrna) (de:gallus gallus mrna for high molecular mass nuclear antigen, partial cds.) (nt:hmna) 33672657_c2_398 7091 23662 2028 675 16252292_c2_399 7092 23663 285 94 284 −25 Pseudomonas AF053982 (de:pseudomonas aeruginosa putative aeruginosa molybdoterin-guanine dinucleotidebiosynthesis protein a (moba) and cytochrome c precursor protein(snr1) genes, complete cds; and unknown genes.) 16276908_c2_401 7093 23664 477 158 186 −13 Caenorhabditis U80846 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid k06a9.) (nt:partial cds; coded for by c. elegans cdna yk50c7.5) 10291515_c2_402 7094 23665 504 167 162 −11 Beta vulgaris S51939 (sr:, beet) (ec:3.2.1.14) 10594193_c2_403 7095 23666 1593 530 13010431_c2_407 7096 23667 438 145 171 −12 Homo sapiens M74027 (sr:homo sapiens (tissue library; lambda-gem-11 (stratagene)) bloo) (de:human mucin-2 gene, partial cds.) 12132305_c2_412 7097 23668 435 144 95 −3 Arabidopsis AL022197 (sr:thalc cress) (de:arabidopsis thaliana thaliana dna chromosome 4, bac clone m7j2 (essaiiproject).) (nt:contains est gb:t45048) 23572156_c3_430 7098 23669 318 105 9784506_c3_432 7099 23670 195 64 15676466_c3_434 7100 23671 2823 940 12984411_c3_437 7101 23672 744 247 162 −10 herpes simplex A27768 (cl:herpesvirus infected cell protein virus type-1 icp34.5) HSV-1 16510068_c3_441 7102 23673 429 142 99 −4 Caenorhabditis Q09456 (de:putative cuticle collagen c09g5.5) elegans 15908191_c3_444 7103 23674 1008 335 146 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 16510066_c3_446 7104 23675 540 179 112 −4 Homo sapiens S16506 (sr:, man) 16538531_c3_448 7105 23676 426 141 126 −7 Pseudomonas P15276 (de:algr3) aeruginosa 10553811_c3_455 7106 23677 657 218 886 −89 Pseudomonas S58668 aeruginosa 11208327_c3_457 7107 23678 1221 406 279 −25 Klebsiella Contig543A GTC ORF with score to: pneumoniae (ai:7000817150) (or:Enterobacter cloacae) 13125952_c3_458 7108 23679 357 118 13141081_c3_459 7109 23680 624 207 129 −7 Enterobacter CONTIG454 GTC ORF with score 229 to: cloacae (ai:7501747091) (or:Klebsiella pneumoniae) 3258261_c3_460 7110 23681 573 190 126 −7 Enterobacter CONTIG454 GTC ORF with score 229 to: cloacae (ai:7501747091) (or:Klebsiella pneumoniae) 14941458_c3_461 7111 23682 1947 648 144 −7 Sus scrofa P18175 (sr:,pig) (de:involucrin) 31892665_c3_469 7112 23683 417 138 122 −8 Arabidopsis AC005396 (sr:thale cress) (de:arabidopsis thaliana thaliana chromosome ii bac t26i20 genomic sequence, complete sequence.) 12144407_c3_471 7113 23684 741 246 124 −8 Klebsiella Contig502A GTC ORF with score 308 to: pneumoniae (ai:7000839882) (or:Enterobacter cloacae) 31461391_c3_474 7114 23685 426 141 107 −6 Aspergillus v1x1fj93.x GTC ORF with score 429 to: fumigatus (ai:177837) (or:Zea mays) (sr:, maize) 31353806_c3_477 7115 23686 531 176 121 −5 Drosophila P13709 (sr:,fruit fly) (de:female sterile homeotic melanoaster protein (fragile-chorion membrane protein)) 13164537_c3_480 7116 23687 585 194 164 −11 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin- castellanii ia(mia) gene, complete cds.) (nt:myosin-i) 16916333_c3_483 7117 23688 1581 526 140 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 12980168_c3_484 7118 23689 2697 898 616 −60 Klebsiella Contig496A GTC ORF with score 897 to: pneumoniae (ai:7000824038) (or:Enterobacter cloacae) 30667907_c3_485 7119 23690 327 108 248 −21 Klebsiella Contig111A GTC ORF with score 248 to: pneumoniae (ai:7000780677) (or:Pseudomonas aeruginosa) 29964406_c3_488 7120 23691 3186 1061 1555 −160 Klebsiella Contig550A GTC ORF with score 2097 to: pneumoniae (ai:7000839066) (or:Enterobacter cloacae) 1445211_c3_489 7121 23692 579 192 152 −9 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 1426292_c3_491 7122 23693 1920 639 239 −29 Mycobacterium Z95558 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 281162.) (nt:rv0552, (mtcy25d10.31), len: 534, probable) 29738256_c3_504 7123 23694 1656 551 401 −37 Klebsiella Contig539A GTC ORF with score 401 to: pneumoniae (ai:7000780696) (or:Pseudomonas aeruginosa) 33703931_c3_505 7124 23695 453 150 127 −8 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna, complete cds.) 13142916_c3_506 7125 23696 1857 618 185 −10 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus 6xCBA/CaJ plenty-of-prolines-101 mrna, complete hybrid cds.) (nt:binds to several sh3 domain containing proteins) 4426040_f1_7 7126 23697 2334 777 1481 −152 Escherichia coli E64738 (cl:penicillin-binding protein Ib) 26382891_f1_8 7127 23698 1110 369 172 −12 Haemophilus Q57152 (de:hypothetical protein hi1436) influenzae 36203766_f1_11 7128 23699 1743 580 1945 −201 Escherichia coli P00893 (ec:4.1.3.18) (de:iii) (acetohydroxy-acid synthase iii large subunit) (als-iii)) 31931417_f1_14 7129 23700 897 298 395 −37 Helicobacter Q48269 (sr:,campylobacter pylori) (ec:2.7.8.8) pylori (de:(phosphatidylserine synthase)) 14344630_f1_15 7130 23701 1050 349 876 −88 Escherichia coli G64961 24742033_f1_17 7131 23702 1521 506 316 −28 Synechococcus P39665 (sr:pcc 7942, anacystis nidulans r2) sp. (de:sphx protein precursor) 13800457_f1_19 7132 23703 387 128 99 −4 slime mold S72442 6519155_f1_20 7133 23704 1527 508 1914 −198 Pseudomonas S65574 aeruginosa 6062901_f1_23 7134 23705 774 257 1200 −122 Pseudomonas S68596 (cl:phou protein) aeruginosa 35438431_f1_25 7T35 23706 450 149 132 −8 Plasmodium M34697 (sr:p.vivax (strain thai; isolate nyu thai) vivax sporozoite dna) (de:p.vivax circumsporozoitc protein gene, complete cds.) (nt:circumsporozoite protein) 14583405_f1_29 7136 23707 1392 463 35367091_f1_37 7137 23708 1134 377 214 −17 Klebsiella Contig435A GTC ORF with score 214 to: pneumoniae (ai:7000780742) (or:Pseudomonas aeruginosa) 35282082_f1_42 7138 23709 1584 527 2106 −218 Escherichia coli P52075 (de:glycolate oxidase subunit glcd) 29808158_f1_45 7139 23710 519 172 277 −24 Escherichia coli P52073 (de:glycolate oxidase subunit glce) 5208568_f1_46 7140 23711 1236 411 1458 −149 Escherichia coli H65083 15913256_f1_53 7141 23712 255 84 96 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 15751568_f1_56 7142 23713 537 178 138 −8 Gallus gallus 150206 (cl:collagen alpha 2(i) chain:fibrillar domesticus collagen carboxyl-terminal homology) (sr:, chicken) 35758563_f1_59 7143 23714 867 288 36383262_f1_65 7144 23715 1599 532 693 −68 Escherichia coli A30374 (mp:82 min) 23956562_f1_68 7145 23716 750 249 117 −7 Streptococcus CONTIG475 GTC ORF with score 117 to: pneumoniae D (ai:7000780773) (or:Pseudomonas aeruginosa) 36197931_f1_71 7146 23717 546 181 92 −2 Homo sapiens AF060154 (sr:human) (de:homo sapiens activated b-cell factor-1(abf-1) mrna, complete cds.) (nt:basic helix-loop-helix protein) 16047717_f1_75 7147 23718 699 232 177 −13 Caenorhabditis Z81138 (de:caenorhabditis elegans cosmid w05b2, elegans complete sequence.) (nt:protein predicted using genefinder; preliminary) 12352067_f1_77 7148 23719 651 216 186 −14 Shewanella AF044582 (de:shewanella putrefaciens nrfg homolog putrefaciens gene, partial cds; and mono-heme c-type cytochrome scya (scya), cytochrome c maturation protein a (ccma), cytochrome c maturation protein b (ccmb),cytochrome c maturation protein c (ccmc), cytoc . . . 34648506_f1_82 7149 23720 1296 431 6147893_f1_84 7150 23721 528 175 158 −10 Rattus norvegicus L48440 (sr:rattus norvegicus male adult bone fracture callus mrna) (de:rattus norvegicus collagen type ii mrna, complete cds.) 31886518_f1_88 7151 23722 426 141 108 −5 Pseudomonas A36128 aeruginosa 36583581_f1_89 7152 23723 945 314 121 −4 Micrococcus JQ0405 luteus 2010026_f1_96 7153 23724 1425 474 169 −10 Klebsiella Contig536A GTC ORF with score 238 to: pneumoniae (ai:7000809741) (or:Pseudomonas aeruginosa) 31892816_f1_98 7154 23725 552 183 143 −10 Aspergillus Contig8378 GTC ORF with score 143 to: fumigatus (ai:7000780803) (or:Pseudomonas aeruginosa) 9864778_f1_100 7155 23726 1302 433 259 −20 Bacillus B69808 subtilis/Bacillus globigii 26023467_f1_107 7156 23727 1149 382 162 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 6504516_f1_108 7157 23728 870 289 127 −5 Nephila clavipes U37520 (de:nephila clavipes dragline silk protein spidroin 1 gene, partial cds.) 12970162_f1_110 7158 23729 270 89 153 −11 Escherichia coli P76075 (de:hypothetical 6.8 kd protein in ldha-fear intergenic region) 10833467_f1_111 7159 23730 357 118 172 −13 Escherichia coli P76076 (de:hypothetical 12.1 kd protein in ldha-fear intergenic region precursor) 16292807_f1_114 7160 23731 216 71 92 −5 Candida albicans CONTIG495 GTC ORF with score 271 to: (ai:439874) (or:Paramecium bursaria Chlorella virus 1) (de:paramecium bursaria chlorella virus 1, complete genome.) (nt:contains pro-rich px motifs; spkpp (20x), peppa) 34258340_f1_117 7161 23732 432 143 246 −21 Haemophilus AF017750 (de:haemophilus ducreyi cyctochrome ducreyi c-type biogenesis protein (ccmh), recombinational dna repair protein (recr), manganese superoxidedismutase (soda), and citg protein homolog (citg) genes, complete cds.) (nt:similar to haemophilus infl . . . 35243753_f1_118 7162 23733 1164 387 826 −82 Escherichia coli P29012 (cc:5.1.1.1) (de:alanine racemase, catabolic precursor,) 2989785_f1_119 7163 23734 627 208 674 −66 Azobacter U94420 (de:azobacter vinelandii aldehyde vinelandii dehydrogenase (aldh) gene, partial cds, cytochrome c5 (cycb) gene, complete cds, and xanthinephosphoribosyltransferase- like protein (xrpt) gene, partial cds.) 10807087_f1_121 7164 23735 753 250 146 −8 Pseudomonas U84154 (de:pseudomonas alcaligene insertion alcaligenes sequence is 1491 putative transproases subunit genes, complete cds.) 25664791_f1_124 7165 23736 459 152 134 −7 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 6456391_f1_126 7166 23737 798 265 165 −12 Klebsiella Contig484A GTC ORF with score 317 to: pneumoniae (ai:7000839520) (or:Enterobacter cloacae) 188551_f1_129 7167 23738 2187 728 509 −49 Enterobacter CONTIG359 GTC ORF with score 644 to: cloacae (ai:7501759807) (or:Klebsiella pneumoniae) 34578957_f1_130 7168 23739 1314 437 104 −3 Pseudomonas X80272 (de:p.putida pprb gene.) putida 36225668_f1_134 7169 23740 1056 351 415 −39 Escherichia coli P32064 (de:glycine cleavage system transcriptional activator) 15098916_f1_135 7170 23741 1200 399 22050386_f1_137 7171 23742 1305 434 380 −35 Enterobacter CONTIG459 GTC ORF with score 533 to: cloacae (ai:7501748159) (or:Klebsiella pneumoniae) 29585308_f1_139 7172 23743 447 148 129 −7 Paralvinella S53787 grasslei 35658417_f1_141 7173 23744 543 180 531 −51 Azotobacter U91902 (de:azotobacter vinelandii pii-protein vinelandii (glnb) and methylammoniumtransport protein (amtb) genes, complete cds.) 24710783_f1_142 7174 23745 1368 455 1687 −173 Azobacter U91902 (de:azotobacter vinelandii pii-protein vinelandii (glnb) and methylammoniumtransport protein (amtb) genes, complete cds.) (nt:amtb) 32290781_f1_148 7175 23746 2103 700 158 −7 mice|C57BL/ P54320 (sr:,mouse) (de:elastin precursor 6xCBA/CaJ (tropoelastin)) hybrid 36066055_f1_149 7176 23747 675 224 274 −24 Klebsiella Contig534A GTC ORF with score 278 to: pneumoniae (ai:7000828862) (or:Enterobacter cloacae) 7053586_f1_150 7177 23748 603 200 121 −5 Epstein-Barr virus P03211 (sr:b9508, human herpesvirus 4) (de:cbna-1 nuclear protein) 31922966_f1_152 7178 23749 432 143 94 −2 Canis familiaris A45195 (cl:guanylate cyclase catalytic domain homology) (sr:, dog) 35258336_f1_158 7179 23750 585 194 109 −4 Aspergillus Contig8154 GTC ORF with score 433 to: fumigatus (ai:177837) (or:Zea mays) (sr:, maize) 7300956_f1_169 7180 23751 1248 415 114 −6 Enterobacter CONTIG444 GTC ORF with score 114 to: cloacae (ai:7000780874) (or:Pseudomonas aeruginosa) 22158291_f1_171 7181 23752 2178 725 232 −16 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) 31376691_f1_188 7182 23753 1308 435 119 −3 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 10416665_f1_193 7183 23754 792 263 577 −56 Bacillus A69813 subtilis/Bacillus globigii 2829131-f1_194 7184 23755 1767 588 102 −5 Aspergillus Contig4845 GTC ORF with score 102 to: fumigatus (ai:7000769406) (or:Pseudomonas aeruginosa) 10269830_f1_195 7185 23756 1083 360 165 −9 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 26798836_f1_201 7186 23757 1254 417 446 −42 Enterobacter CONTIG498 GTC ORF with score 446 to: cloacae (ai:7000780906) (or:Pseudomonas aeruginosa) 14742910_f1_209 7187 23758 2880 959 108 −2 Dictyostelium AB009080 (sr:dictyostelium discoideum (str:ax2) dna) discoideum (de:dictyostelium discoideum gene for trfa, complete cds.) 1380466_f2_212 7188 23759 1425 474 34470377_f2_217 7189 23760 801 266 102 −2 Dictyostelium Q04503 (sr:,slime mold) (de:prespore protein dp87 discoideum precursor) 11197530_f2_221 7190 23761 516 171 164 −11 human U92288 (fn:helicase, helicase-primase complex) herpesvirus (de:human herpesvirus 6 serotype b type 6 HHV-6 putative major immediate-early genes.) (nt:similar to hhv6a u86. region ie-b) 16179501_f2_238 7191 23762 2253 750 12972807_f2_239 7192 23763 621 206 632 −62 Pseudomonas S65574 aeruginosa 3339700_f2_240 7193 23764 849 282 1423 −145 Pseudomonas S68595 (cl:inner membrane protein malk:atp- aeruginosa binding cassette homology) 524131_f2_242 7194 23765 996 331 229 −19 Pseudomonas AF031898 (de:pseudomonas putida chemotaxis and putida motility gene region, flagellarstructural protein flha (flha) gene, partial cds; and flagellarstructural protein flhf (flhf), motility sigma factor flia (flia), response regulator chey (chey), dep . . . 10985468_f2_246 7195 23766 609 202 163 −12 Klebsiella Contig546A GTC ORF with score 314 to: pneumoniae (ai:7000835524) (or:Enterobacter cloacae) 31492955_f2_250 7196 23767 219 72 96 −4 Alphaherpesvirus P07646 (sr:rice,prv) (de:glycoprotein gp63 pseudorabies precursor) virus PRV 14947625_f2_251 7197 23768 483 160 13152041_f2_267 7198 23769 447 148 98 −2 herpes simplex Z86099 (fn:immediate early protein; virus type 2 transcriptional) (de:herpes simplex virus HSV-2 type 2 (strain hg52), complete genome.) 32677156_f2_268 7199 23770 585 194 413 −38 Escherichia coli P45504 (de:glcg protein) 5993942_f2_269 7200 23771 1830 609 133 −5 Acanthamoeba P10569 (sr:,amoeba) (dc:myosin ic heavy chain) castellanii 1353576_f2_275 7201 23772 1035 344 709 −70 Klebsiella Contig542A GTC ORF with score 833 to: pneumoniae (ai:7000819569) (or:Enterobacter cloacae) 21775451_f2_276 7202 23773 666 221 98 −3 Enterobacter CONTIG355 GTC ORF with score 260 to: cloacae (ai:7501784209) (or:Klebsiella pneumoniae) 15760205_f2_279 7203 23774 2397 798 195 −12 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 672267_f2_290 7204 23775 846 281 269 −23 Klebsiella Contig542A GTC ORF with score 658 to: pneumoniae (ai:7000823162) (or:Enterobacter cloacae) 4792715_f2_291 7205 23776 759 252 1120 −113 Pseudomonas P50597 (cc:2.7.7.56) (de:nucleotidyltransferase)) aeruginosa 21582628_f2_293 7206 23777 522 173 100 −5 Enterobacter CONTIG507 GTC ORF with score 119 to: cloacae (ai:7501780229) (or:Klebsiella pneumoniae) 16617257_f2_294 7207 23778 693 230 11213558_f2_299 7208 23779 2748 915 366 −32 Mycobacterium P71663 (de:hypothetical transcriptional regulator tuberculosis cy21b4.12) 10292793_f2_301 7209 23780 2541 846 99 −1 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 13161077_f2_303 7210 23781 1470 489 16520888_f2_304 721I 23782 573 190 128 −5 Alphaherpesvirus P33479 (sr:kaplan, prv) (de:immediate-early pseudorabies protein ie 180) virus PRV 34464567_f2_307 7212 23783 1608 535 92 −1 Brassica Z74892 (fn:cell wall protein) (de:b.oleracea mrna oleracea for glycine-rich protein.) 33290918_f2_308 7213 23784 240 79 335 −30 Salmonella U23405 (de:salmonella typhimurium ribosomal choleracsuis protein 128 (rpmb), ribosomalprotein 133 serotype (rpmg) and 8-hydroxyguanine-dna typhimurium glycosylase (mutmst)genes, compete cds.) (nt:ribosomal protein 128) 22552268_f2_313 7214 23785 1590 529 1446 −148 Escherichia coli P23883 (cc:1.2.1.3) (de:putative aldehyde dehydrogenase,) 10980035_f2_319 7215 23786 1686 561 364 −33 Klebsiella Contig532A GTC ORF with score 632 to: pneumoniae (ai:7000771478) (or:Pseudomonas aeruginosa) 22852016_f2_321 7216 23787 2667 888 114 −3 Escherichia coli D90777 (sr:escherichia coli (strain:k12) dna, clone_lib:kohara lambda minise) (de:e.coli genomic dna, kohara clone #266(31.1-3 1.5 min.).) (nt:orf_id:o265#2; similar to (swissprot accession) 12363216_f2_324 7217 23788 1152 383 93 −4 longfin squid S56117 (sr:, longfin squid) 31458191_f2_327 7218 23789 2415 804 163 −8 Cyanobacterium S77148 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 36218787_f2_337 7219 23790 1692 563 762 −75 Cyanobacterium S76102 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 32525341_f2_343 7220 23791 597 198 101 −3 Saccharomyces P53832 (sr:,baker's yeast) (de:precursor) cerevisiae 131580_f2_346 7221 23792 1302 433 629051_f2_352 7222 23793 351 116 122 −6 Homo sapiens P12036 (sr:,human) (de:neurofilament triplet h protein (200 kd neurofilament protein) (nf-h)) 11876687_f2_354 7223 23794 993 330 17001093_f2_356 7224 23795 786 261 129 −6 Klebsiella Contig517A GTC ORF with score 324 to: pneumoniae (ai:7000795560) (or:Pseudomonas aeruginosa) 32229832_f2_357 7225 23796 1182 393 170 −10 Escherichia coli P77589 (de:putative 3-hydroxyphenylpropionic acid transporter) 14665783_f2_362 7226 23797 1563 520 215 −17 Klebsiella Contig534A GTC ORF with score 215 to: pneumoniae (ai:7000781067) (or:Pseudomonas aeruginosa) 22516518_f2_364 7227 23798 426 141 104 −4 Strongylo- A43426 (cl:unassigned collagens:fibrillarcollagen centrotus carboxyl-terminal homology:von purpuratus willebrand factor type c repeat homology) (sr:, purple urchin) 34478441_f2_366 7228 23799 354 117 265 −23 Erwinia P40128 (de:cyay protein) chrysanthemi 16095441_f2_368 7229 23800 522 173 143 −9 mice|C57BL/ P28704 (sr:,mouse) (de:binding protein h-2riibp)) 6xCBA/CaJ hybrid 32600401_f2_371 7230 23801 1932 643 117 −6 Enterobacter CONTIG444 GTC ORF with score 418 to: cloacae (ai:7501778878) (or:Klebsiella pneumoniae) 11064842_f2_372 7231 23802 486 161 120 −8 Enterobacter CONTIG444 GTC ORF with score 451 to: cloacae (ai:7501778879) (or:Klebsiella pneumoniae) 16276432_f2_377 7232 23803 1191 396 448 −42 Escherichia coli P27841 (de:magnesium and cobalt transport protein cora) 16126031_f2_380 7233 23804 1785 594 592 −57 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-g1 genes, complete cds.) 13152013_f2_382 7234 23805 4881 1626 466 −40 Escherichia coli AF044499 (de:escherichia coli strain ec50 rhse accessory genetic element vgreprotein, core protein, and dsorf-e5 genes, complete cds.) 4317192_f2_383 7235 23806 444 147 4462532_f2_385 7236 23807 690 229 116 −5 Klebsiella Contig164A GTC ORF with score 201 to: pneumoniae (ai:7000846209) (or:Enterobacter cloacae) 3148403_f2_388 7237 23808 525 174 260 −22 Rhodobacter P31078 (sr:,rhodopseudomonas capsulata) capsulatus (de:petp protein) 31663580_f2_390 7238 23809 1341 446 33878905_f2_393 7239 23810 942 313 130 −6 Klebsiella Contig442A GTC ORF with score 130 to: pneumoniae (ai:7000781098) (or:Pseudomonas aeruginosa) 13025755_f2_395 7240 23811 378 125 122 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat proteins discoideum sp96) 4822650_f2_396 7241 23812 1791 596 1127 −116 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 78/162.) (nt:rv 1739c, (mtcy04c 12.24c, mtcy28.01), len: 560.) 13770632_f2_401 7242 23813 1665 554 184 −11 Klebsiella Contig487A GTC ORF with score 567 to: pneumoniae (ai:7000825229) (or:Enterobacter cloacae) 2869385_f2_402 7243 23814 513 170 326 −30 Klebsiella Contig420A GTC ORF with score 326 to: pneumoniae (ai:7000781107) (or:Pseudomonas aeruginosa) 34245918_f2_406 7244 23815 1137 378 285 −25 Klebsiella Contig486A GTC ORF with score 285 to: pneumoniae (ai:7000781111) (or:Pseudomonas aeruginosa) 34661457_f2_407 7245 23816 756 251 157 −10 Enterobacter CONTIG484 GTC ORF with score 294 to: cloacae (ai:7501740575) (or:Klebsiella pneumoniae) 31519466_f2_409 7246 23817 495 164 146 −9 human U92288 (fn:helicase, helicase-primase complex) herpesvirus type 6 (de:human herpesvirus 6 serotype b HHV-6 putative major immediate-earlygenes.) (nt:similar to hhv6a u86, region ie-b) 11760082_f2_412 7247 23818 417 138 287 −25 Enterobacter CONTIG484 GTC ORF with score 287 to: cloacae (ai:7000781117) (or:Pseudomonas aeruginosa) 32048303_f3_430 7248 23819 1020 339 199 −16 Klebsiella Contig547A GTC ORF with score 199 to: pneumoniae (ai:7000781135) (or:Pseudomonas aeruginosa) 15833341_f3_432 7249 23820 540 179 549 −53 Salmonella S15940 (cl:acetolactate synthase small chain) choleraesuis (ec:4.1.3.18) serotype typhimurium 11758592_f3_433 7250 23821 1029 342 1132 −115 Rhodospirillum D50654 (sr:rhodospirillum molischianum dna) molischianum (de:rhodospirillum molischianum bchz, pufb, pufa, pufl, pufm pufc andilvc genes, partial and complete cds.) 10829591_f3_437 7251 23822 636 211 313 −28 Escherichia coli H64961 2444792_f3_438 7252 23823 189 62 106 −6 Enterococcus CONTIG430 GTC ORF with score 106 to: faccium C (ai:7000781143) (or:Pseudomonas aeruginosa) 31878342_f3_442 7253 23824 2409 802 3434 −9999 Pseudomonas S65573 aeruginosa 26691455_f3_447 7254 23825 1059 352 185 −11 Cyanobacterium S76492 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 7114587_f3_451 7255 23826 987 328 207 −17 Enterobacter CONTIG480 GTC ORF with score 314 to: cloacae (ai:7501786875) (or:Klebsiella pneumoniae) 36538326_f3_452 7256 23827 960 319 161 −12 Enterobacter CONTIG480 GTC ORF with score 161 to: cloacae (ai:7000781157) (or:Pseudomonas aeruginosa) 12531916_f3_453 7257 23828 516 171 126 −7 Homo sapiens X87248 (sr:human) (de:h.sapiens mrna for hp8 protein.) 26182663_f3_457 7258 23829 921 306 111 −4 Caenorhabditis Z81503 (de:caenorhabditis elegans cosmid f14f7, elegans complete sequence.) (nt:predicted using genefinder; similar to collagen;) 32704167_f3_459 7259 23830 1794 597 803 −80 Escherichia coli P52073 (de:glycolate oxidase subunit glce) 36064168_f3_460 7260 23831 888 295 91 −2 Aspergillus Contig4770 GTC ORF with score 277 to: (ai:69657) fumigatus (or:Human herpesvirus 4) (cl:epstein-barr virus nuclear antigen) 14711378_f3_462 7261 23832 192 63 241 −20 Acinetobacter P42453 (de:rubredoxin (rd)) calcoaceticus 14148458_f3_463 7262 23833 1206 401 716 −71 Acinetobacter sp. Z46863 (fn:necessary for growth on alkane) ADP1 (de:acinetobacter sp. cysd, cobq, sodm, lyss, ruba, rubb, estb, oxyr, ppk, mtga, orf2 and orf3 genes.) 1412667_f3_464 7263 23834 363 120 239 −20 Pseudomonas P05384 (de:dna-binding protein hu) aeruginosa 16682081_f3_465 7264 23835 528 175 22708580_f3_476 7265 23836 1719 572 326 −29 Streptomyces AL031031 (de:streptomyces coelicolor cosmid 7c7.) coelicolor (nt:sc7c7.17, possible transcriptional regulatory) 23906253_f3_477 7266 23837 687 228 195 −15 Escherichia coli P27846 (de:hypothetical 22.5 kd protein in recq-pldb intergenic region) 16488588_f3_478 7267 23838 1218 405 35250393_f3_484 7268 23839 831 276 155 −8 human U13194 (fn:transcriptional regulation) (de:human herpesvirus type 6 herpesvirus 6 replication origin-binding HHV-6 protein (hdrfo), partial cds, helicase-primase component (hdrf1), virion protein(hd1f1), putative helicase (hdrf2), putative phosphoprotein(edrf1), replica . . . 10397707_f3_485 7269 23840 492 163 282 −25 Cyanobacterium S74932 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 30157801_f3_488 7270 23841 669 222 1069 −108 Pseudomonas P50587 (ec:2.4.2.10) (de:orotate aeruginosa phosphoribosyltransferase, (oprt) (oprtase)) 16051032_f3_492 7271 23842 1932 643 699 −70 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 79/162.) (nt:rv1771, (mtcy28.37), probable oxidoreductase, :) 12942780_f3_498 7272 23843 612 203 106 −3 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein discoideum sp96) 16931883_f3_503 7273 23844 681 226 117 −5 Aspergillus Contig10147 GTC ORF with score 245 to: (ai:175201) fumigatus (or:Chlamydomonas reinhardtii) (de:chlamydomonas reinhardtii vsp-3 mrna, complete cds.) (nt:amino acid feature: rod protein domain. aa 266 . . . ) 16135455_f3_506 7274 23845 216 71 91 −3 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 11222791_f3_507 7275 23846 561 186 388 −36 Enterobacter CONTIG169 GTC ORF with score 388 to: cloacae (ai:7000781212) (or:Pseudomonas aeruginosa) 31276011_f3_508 7276 23847 792 263 446 −42 Haemophilus P44952 (de:dna repair protein radc homolog) influenzae 35258342_f3_520 7277 23848 1500 499 34489380_f3_525 7278 23849 675 224 92 −4 Enterobacter CONTIG499 GTC ORF with score 98 to: cloacae (ai:7501754485) (or:Klebsiella pneumoniae) 12906300_f3_532 7279 23850 1389 462 1405 −144 Escherichia coli P29011 (ec:1.4.99.1) (de:d-amino acid dehydrogenase small subunit,) 30553580_f3_538 7280 23851 474 157 499 −48 Azotobacter U94420 (de:azotobacter vinelandii aldehyde vinelandii dehydrogenase (aldh) gene, partial cds, cytochrome c5 (cycb) gene, complete cds, and xanthinephosphoribosyltransferase- like protein (xrpt) gene, partial cds.) (nt:one of the two c-type cytochromes i . . . 15752306_f3_543 7281 23852 1113 370 326 −30 Klebsiella Contig484A GTC ORF with score 499 to: pneumoniae (ai:7000839522) (or:Enterobacter cloacae) 3234627_f3_557 7282 23853 402 133 144 −10 Klebsiella Contig488A GTC ORF with score 144 to: pneumoniae (ai:7000781262) (or:Pseudomonas aeruginosa) 35817918_f3_559 7283 23854 861 286 108 −4 Indian corn P23444 (sr:,maize) (de:histonc h1) 17067638_f3_562 7284 23855 546 181 94 −5 Enterobacter CONTIG455 GTC ORF with score 94 to: cloacae (ai:7000781267) (or:Pseudomonas aeruginosa) 25489591_f3_563 7285 23856 987 328 90 −3 Tachyglossus P35311 (sr:,australian echidna) (de:sperm aculeatus protamine p1) aculcatus 32682262_f3_564 7286 23857 468 155 444 −42 Escherichia coli P32698 (de:hypothetical 15.7 kd protein in apha-uvra intergenic region (o138)) 16299163_f3_574 7287 23858 492 163 101 −3 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 11813892_f3_575 7288 23859 468 155 145 −9 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 29801083_f3_578 7289 23860 498 165 261 −23 Acinetobacter CONTIG105 GTC ORF with score 109 to: (ai:59485) baumannii C (or:Saccharomyces cerevisiae) (sr:baker's yeast) (de:s.cerevisiae chromosome ix cosmid 9168.) (nt:ma15, sta1, : 1367, cai: 0.3, amyh yeast p08640) 14932841_f3_579 7290 23861 1593 530 24510140_f3_581 7291 23862 504 167 298 −26 Escherichia coli P40679 (de:regulator of nucleoside diphosphate kinase) 34432058_f3_591 7292 23863 1287 428 22057076_f3_593 7293 23864 570 189 541 −52 Escherichia coli AF044503 (de:escherichia coli strain ec11 unknown (498), hcp gene, complete cds; and rhsg accessory genetic element vgrg protein, core component anddsorf-gl genes, complete cds.) (nt:similar to vibrio secreted protein hcps81006) 26679093_f3_594 7294 23865 717 238 101 −3 Streptomyces P20186 (de:hypothetical 35.5 kd protein in fradiae transposon tn4556) 32538542_f3_598 7295 23866 783 260 26667205_f3_602 7296 23867 609 202 190 −14 equine P28968 (sr:ab4p, ehv-1) (de:glycoprotein x herpesvirus type 1 precursor) EVH-1 16494830_f3_605 7297 23868 267 88 113 −5 Saccharomyces P47179 (sr:,baker's yeast) (de:precursor) cerevisiae 13022955_f3_608 7298 23869 420 139 93 −2 Arabidopsis P40602 (sr:,mouse-ear cress) (de:enter-specific thaliana proline-rich protein apg precursor) 16491433_f3_609 7299 23870 1578 525 895 −90 Escherichia coli D64895 6722831_f3_610 7300 23871 1008 335 168 −11 Klebsiella Contig490A GTC ORF with score 124 to: pneumoniae (ai:4000725427) (or:Mus spretus) (sr:western wild mouse) (de:mus spretus sex determining protein (sry) gene, complete cds.) (nt:hmg box transcription factor) 22785408_f3_612 7301 23872 402 133 109 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 9800456_f3_613 7302 23873 531 176 246 −21 Escherichia coli P76113 (ec:1.—.—.—)(de:(ec 1.—.—.—)) 31852336_f3_614 7303 23874 627 208 109 −6 longfin squid S56117 (sr:, longfin squid) 22010400_f3_617 7304 23875 1572 523 173 −12 Enterobacter CONTIG336 GTC ORF with score 333 to: cloacae (ai:7000797020) (or:Pseudomonas aeruginosa) 23645215_f3_619 7305 23876 519 172 15678892_f3_621 7306 23877 498 165 324 −29 Acinetobacter CONTIG171 GTC ORF with score 324 to: baumannii C (ai:7000781326) (or:Pseudomonas aeruginosa) 30720317_f3_624 7307 23878 1719 572 635 −64 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 481162.) (nt:rv1063c, (mtv017.16c), len: 360. unknown but) 5963555_f3_631 7308 23879 693 230 157 −9 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia castellanii (mia) gene, complete cds.) (nt:myosin-i) 12397630_f3_633 7309 23880 402 133 98 −5 Aspergillus Contig4770 GTC ORF with score 277 to: (ai:69657) fumigatus (or:Human herpesvirus 4) (cl:epstein-barr virus nuclear antigen) 33446956_f3_634 7310 23881 483 160 126 −8 Klebsiella Contig394A GTC ORF with score 151 to: pneumoniae (ai:7000788901) (or:Pseudomonas aeruginosa) 5125180_c1_635 7311 23882 2817 938 1253 −127 Escherichia coli P21865 (ec:2.7.3.—) (de:sensor protein kdpd,) 574137_c1_642 7312 23883 1071 356 1142 −116 Escherichia coli P16456 (ec:2.7.9.3) (de:(selenium donor protein)) 11822081_c1_646 7313 23884 594 197 101 −3 Homo sapiens M57939 (sr:human dna) (de:human small nuclear ribonucleoprotein (u1-70k) gene, exon 10 and 11.) 31385816_c1_647 7314 23885 972 323 160 −8 herpes simplex Z86099 (fn:immediate early protein; virus type 2 transcriptional) (de:herpes simplex virus HSV-2 type 2 (strain hg52), complete genome.) 13174207_c1_648 7315 23886 573 190 133 −6 Nephila clavipes AF027735 (de:nephila clavipes minor ampullate silk protein misp1 mrna, partial cds.) 22396017_c1_650 7316 23887 729 242 118 −4 Saccharopoly- P07287 (sr:,streptomyces erythraeus) (cc:2.1.1.48) spora erythraca (de:resistance protein) (nmt)) 3395965_c1_655 7317 23888 912 303 262 −23 Enterobacter CONTIG472 GTC ORF with score 425 to: cloacae (ai:7000783760) (or:Pseudomonas aeruginosa) 14944705_c1_658 7318 23889 294 97 105 −6 Aspergillus Contig8697 GTC ORF with score 105 to: fumigatus (ai:7000781363) (or:Pseudomonas aeruginosa) 34464756_c1_659 7319 23890 978 325 166 −9 blue mussel AF043944 (sr:blue mussel) (de:mytilus edulis nongradient byssal precursor, mrna, complete cds.) (nt:prccol-ng) 22160432_c1_661 7320 23891 750 249 14194382_c1_663 7321 23892 750 249 273 −24 Rhizobium Q52828 (de:gsta protein) leguminosarum 12979080_c1_675 7322 23893 681 226 157 −9 Saccharomyces X89715 (sr:baker's yeast) (de:s.cerevisiae aob567, cerevisiae aof1001, aoe110, aoe264 and aoe130 genes.) 29949032_c1_679 7323 23894 777 258 132 −6 Caenorhabditis Z81053 (de:caenorhabditis elegans cosmid elegans e02a10, complete sequence.) (nt:predicted using genefinder) 34244468_c1_680 7324 23895 426 141 129 −9 Klebsiella Contig554A GTC ORF with score 129 to: pneumoniae (ai:7000781385) (or:Pseudomonas aeruginosa) 22739780_c1_683 7325 23896 216 71 237 −20 Pseudomonas P17323 (de:lipopeptide precursor) aeruginosa 36219556_c1_686 7326 23897 471 156 119 −6 mice|C57BL/ P55194 (sr:,mouse) (de:sh3-binding protein 3bp-1) 6xCBA/CaJ hybrid 17066253_c1_689 7327 23898 1083 360 1483 −152 Pseudomonas S61402 aeruginosa 34479057_c1_690 7328 23899 633 210 260 −22 Serratia AF028736 (fn:unknown) (de:serratia marcescens site marcescens specific recombinase (xerc) and dna helicase ii (uvrd) genes, complete cds.) (nt:orf238) 31776536_c1_700 7329 23900 597 198 128 −6 Dictyostelium P14328 (sr:,slime mold) (de:spore coat protein discoideum sp96) 15714805_c1_702 7330 23901 1575 524 138 −6 Brassica napus S31415 (cl:phaseolus glycine-rich cell wall protein 1.8) (sr:, rape) 12970716_c1_707 7331 23902 576 191 105 −3 Pseudomonas M57551 (sr:p.aeruginosa (strain 8830) dna) aeruginosa (de:p.aeruginosa transcription regulatory protein (algp) gene, complete cds.) (nt:putative) 24687543_c1_709 7332 23903 2079 692 1477 −151 Escherichia coli P17447 (de:high-affinity choline transport protein) 4318783_c1_714 7333 23904 1488 495 93 −3 longfin squid S56117 (sr:, longfin squid) 36409707_c1_719 7334 23905 2112 703 1852 −191 Escherichia coli P09980 (ec:3.6.1.—)(de:atp-dependent dna helicase rep,) 9963426_c1_720 7335 23906 1737 578 542 −52 Escherichia coli P07003 (cc:1.2.2.2) (de:(pox) (pyruvate dehydrogenase (ubiquinone))) 16895400_c1_730 7336 23907 1464 487 289 −25 Klebsiella Contig364A GTC ORF with score 289 to: pneumoniae (ai:7000781435) (or:Pseudomonas aeruginosa) 34455283_c1_736 7337 23908 1350 449 177 −10 human U13194 (fn:transcriptional regulation) (de:human herpesvirus type 6 herpesvirus 6 replication origin-binding HHV-6 protein (hdrfo), partial cds, helicase-primase component (hdrf1), virion protein(hd1f1), putative helicase (hdr12), putative phosphoprotein(cdrf1). replica . . . 10351592_c1_740 7338 23909 1695 564 790 −78 Escherichia coli P75919 (de:hypothetical 55.9 kd protein in csgc-mdog intergenic region) 4505201_c1_742 7339 23910 1347 448 135 −5 African malaria S27770 (sr:, african malaria mosquito) mosquito 5165652_c1_745 7340 23911 513 170 110 −5 Enterobacter CONTIG508 GTC ORF with score 110 to: cloacae (ai:7000781450) (or:Pseudomonas aeruginosa) 16539657_c1_746 7341 23912 1464 487 1065 −108 Pseudomonas A42800 (cl:beta-alanine--pyruvate transaminase) putida (ec:2.6.1.18) 36141662_c1_752 7342 23913 582 193 10625830_c1_756 7343 23914 498 165 570 −55 Haemophilus P43792 (ec:3.6.1.23) (de:(dutpase) (dutp influenzae pyrophosphatase)) 22383281_c1_757 7344 23915 438 145 140 −8 infectious bovine Z78205 (de:bovine herpesvirus type 1 u122-35 rhinotracheitis genes.) (nt:very large tegument protein) virus 30582333_c1_760 7345 23916 378 125 118 −6 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 5323342_c1_761 7346 23917 957 318 736 −73 Methanococcus Q60382 (ec:2.7.2.8) (de:(n-acetylglutamate 5- jannaschii phosphotransferase)) 10018806_c1_763 7347 23918 1419 472 13183125_c1_771 7348 23919 795 264 1378 −141 Pseudomonas U38241 (sr:pseudomonas aeruginosa strain=pao1) aeruginosa (de:pseudomonas aeruginosa orotate phophoribosyl transferase (pyre), catabolite repression control protein (crc) and rnaseph (rph) genes, complete cds.) 26675827_c1_772 7349 23920 441 146 296 −26 Enterococcus CONTIG487 GTC ORF with score 296 to: faecium C (ai:7000781477) (or:Pseudomonas aeruginosa) 30349080_c1_775 7350 23921 708 235 647 −63 Escherichia coli P24234 (ec:2.7.4.8) (de:guanylate kinase, (gmp kinase)) 22863535_c1_777 7351 23922 2022 673 1984 −205 Escherichia coli P17580 (cc:3.1.7.2) (de:((ppgpp)asc) (penta- phosphate guanosine-3′- pyrophosphohydrolase)) 26585441_c1_780 7352 23923 693 230 132 −6 Homo sapiens D64137 (fn:cdk-inhibitor) (sr:homo sapiens dna) (de:human kip2 gene for cdk-inhibitor p57kip2, complete cds (exon 1-4).) 16510417_c1_781 7353 23924 423 140 110 −5 equine D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus type 1 (de:equine herpesvirus 1 dna for tegument EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 11744761_c1_783 7354 23925 1518 505 104 −2 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 14948915_c1_784 7355 23926 429 142 14728805_c1_788 7356 23927 258 85 145 −10 Klebsiella Contig542A GTC ORF with score 145 to: pneumoniae (ai:7000781493) (or:Pseudomonas aeruginosa) 21914093_c1_789 7357 23928 519 172 112 −7 Klebsiella Contig544A GTC ORF with score 302 to: pneumoniae (ai:7000806916) (or:Pseudomonas aeruginosa) 35588308_c1_797 7358 23929 1500 499 31303930_c1_800 7359 23930 1872 623 14557691_c1_801 7360 23931 795 264 803 −80 Escherichia coli U28377 (de:escherichia coli k-12 genome; approximately 65 to 68 minutes.) (nt:orf o274) 12009591_c1_803 7361 23932 1248 415 804 −80 Escherichia coli P26601 (ec:2.5.1.—) (de:polyprenyltransferase)) 21689791_c1_808 7362 23933 678 225 92 −2 Aspergillus Contig136 GTC ORF with score 783 to: (ai:358810) fumigatus (or:Vigna unguiculata) (sr:cowpea) (de:v.unguiculata mrna for extensine-like protein, ext127.) 32500655_c1_810 7363 23934 1287 428 592 −57 Bacillus O07585 (de:hypothetical 49.9 kd protein in subtilis/Bacillus cita-sspb intergenic region) globigii 13911642_c1_812 7364 23935 513 170 129 −8 Homo sapiens S16506 (sr:, man) 24900842_c1_815 7365 23936 1035 344 310 −28 Klebsiella Contig480A GTC ORF with score 653 to: pneumoniae (ai:7000832568) (or:Enterobacter cloacae) 36331452_c1_817 7366 23937 264 87 207 −17 Klebsiella Contig480A GTC ORF with score 207 to: pneumoniae (ai:7000781522) (or:Pseudomonas aeruginosa) 14932050_c1_819 7367 23938 1560 519 25817283_c1_827 7368 23939 315 104 329 −30 Clostridium Contig240H GTC ORF with score 104 to: acetobutylicum (ai:7500980948) (or:Pyrococcus horikoshii) (sr:pyrococcus horikoshii (str:ot3) dna) (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) 10444186_c1_831 7369 23940 276 91 338 −31 Enterobacter CONTIG310 GTC ORF with score 338 to: cloacae (ai:7000781536) (or:Pseudomonas aeruginosa) 2007192_c1_832 7370 23941 306 101 4819803_c1_836 7371 23942 963 320 231 −19 Klebsiella Contig210A GTC ORF with score 428 to: pneumoniae (ai:7000830397) (or:Enterobacter cloacae) 3236680_c1_839 7372 23943 1716 571 292 −25 Enterobacter CONTIG499 GTC ORF with score 292 to: cloacae (ai:7000781544) (or:Pseudomonas aeruginosa) 33694576_c1_843 7373 23944 2922 973 346 −30 Enterobacter CONTIG503 GTC ORF with score 808 to: cloacae (ai:7501737837) (or:Klebsiella pneumoniae) 14957057_c1_846 7374 23945 507 168 106 −5 Cyanobacterium S75171 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 22741708_c1_847 7375 23946 294 97 15725901_c1_848 7376 23947 903 300 1338 −136 Pseudomonas AF056000 (de:pseudomonas aeruginosa camp- aeruginosa dependent protein kinase (ppka) gene, complete cds.) (nt:ppka; protein kinase a) 24880037_c2_849 7377 23948 1008 335 144 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 10026908_c2_850 7378 23949 429 142 120 −7 Aspergillus Contig8932 GTC ORF with score 246 to: (ai:175141) fumigatus (or:Chlamydomonas eugametos) (de:chlamydomonas eugametos wp6 mrna, complete cds.) (nt:amino acid feature: n- glycosylation sites, aa 41 . . . ) 36604083_c2_851 7379 23950 249 82 103 −5 Cyanobacterium 577457 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 14323908_c2_852 7380 23951 576 191 180 −12 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia castellanii (mia) gene, complete cds.) (nt:myosin-i) 16119517_c2_854 7381 23952 1593 530 24427191_c2_857 7382 23953 366 121 12588456_c2_859 7383 23954 1713 570 115 −6 Klebsiella Contig559A GTC ORF with score 115 to: pneumoniae (ai:7000781564) (or:Pseudomonas aeruginosa) 12197955_c2_860 7384 23955 645 214 318 −28 Aquifex aeolicus D70380 6724206_c2_861 7385 23956 2574 857 639 −62 Escherichia coli JQ1475 (cl:methyl-accepting chemotaxis protein) 16927257_c2_869 7386 23957 945 314 151 −9 mice S50883 (sr:mice macrophage) (de:putative transcription regulator {clone t2, repetitive sequence}(mice, macrophage, mrna, 1263 nt).) (nt:method: conceptual translation supplied by author.) 21892658_c2_870 7387 23958 927 308 579 −56 Cyanobacterium S75443 (sr:pcc 6803,,pcc 6803) (sr:pcc 6803,) synechocystis 16495768_c2_871 7388 23959 651 216 117 −7 Enterobacter CONTIG491 GTC ORF with score 117 to: cloacae (ai:7000781576) (or:Pseudomonas aeruginosa) 22474041_c2_872 7389 23960 432 143 99 −5 Enterobacter CONTIG491 GTC ORF with score 99 to: cloacae (ai:7000781577) (or:Pseudomonas aeruginosa) 12126457_c2_875 7390 23961 891 296 120 −4 Acanthamoeba AF085185 (de:acanthamoeba castellanii myosin-ia castellanii (mia) gene, complete cds.) (nt:myosin-i) 4942883_c2_876 7391 23962 846 281 130 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35291681_c2_885 7392 23963 411 136 97 −3 Caenorhabditis U41538 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid r04e5.) (nt:proline rich; coded for by c. elegans cdna) 9900326_c2_887 7393 23964 840 279 179 −12 Klebsiella Contig470A GTC ORF with score 179 to: pneumoniae (ai:7000781592) (or:Pseudomonas aeruginosa) 7283180_c2_891 7394 23965 381 126 36432958_c2_892 7395 23966 900 299 14223405_c2_893 7396 23967 276 91 13151591_c2_894 7397 23968 762 253 139 −6 Mycobacterium Z81331 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 123/162.) (nt:rv2839c, (mtcy16b7.03), len: 900. probable infb,) 10286426_c2_897 7398 23969 486 161 93 −2 Pseudomonas AF004848 (de:pseudomonas fluorescens alkaline fluorescens protease, protease inhibitor, zinc-protease transporter (aprd), zinc-protease transporter (apre), and zinc-protease transporter (aprf) genes. complete cds.) 15907882_c2_898 7399 23970 405 134 91 −3 Brugia malayi S46964 33854132_c2_901 7400 23971 690 229 131 −8 Escherichia coli G64794 10005417_c2_904 7401 23972 1395 464 2102 −217 Pseudomonas P19572 (ec:4.1.1.20) (de:diaminopimelate aeruginosa decarboxylase, (dap decarboxylase)) 35440766_c2_908 7402 23973 432 143 91 −2 Myxococcus JC6146 xanthus 32708291_c2_911 7403 23974 771 256 144 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22364181_c2_913 7404 23975 537 178 148 −9 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early protein pseudorabies ie 175) virus PRV 15805278_c2_914 7405 23976 828 275 142 −7 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 31817541_c2_916 7406 23977 567 188 138 −9 Mycobacterium U88962 (de:mycobacterium tuberculosis unknown tuberculosis protein gene, partial cds.) 4164542_c2_918 7407 23978 216 71 24666532_c2_919 7408 23979 489 162 100 −3 Pseudomonas X80272 (de:p.putida pprb gene.) putida 7119777_c2_922 7409 23980 1035 344 134 −8 Escherichia coli Q46868 (de:hypothetical 13.8 kd protein in ribb-glgs intergenic region) 16695138_c2_923 7410 23981 1578 525 203 −14 mice|C57BL/ P05143 (sr:,mouse) (de:proline-rich protein mp-3 6xCBA/CaJ (fragment)) hybrid 16927006_c2_928 7411 23982 723 240 144 −8 Rhodobacter P14172 (sr:,rhodopseudomonas capsulata) capsulatus (de:hypothetical 28.2 kd protein in ampr 5′region 4318751_c2_929 7412 23983 1593 530 671 −66 Cyanobacterium Q55364 (sr:pcc 6803,) (de:hypothetical 49.7 kd synechocystis protein) 875316_c2_935 7413 23984 1083 360 819 −81 Pseudomonas P10343 (de:hypothetical 42.6 kd protein in amyloderamosa isoamylase 3′region 16901637_c2_937 7414 23985 741 246 639 −62 Bacillus P42085 (cc:2.4.2.—) (de:xanthine subilis/Bacillus phosphorihosyltransferase,) globigii 33616458_c2_938 7415 23986 195 64 93 −4 Candida albicans CONTIG105 GTC ORF with score 296 to: (ai:440222) 7 (or:Paramecium bursaria Chlorella virus 1) (de:paramecium bursaria chlorella virus 1, complete genome.) (nt:pro-, lys-rich, papk (30x): similar to wheat pro-.) 30333441_c2_940 7416 23987 471 156 120 −7 Orf virus D34768 15752140_c2_942 7417 23988 267 88 97 −4 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase- binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein;) 14097151_c2_946 7418 23989 423 140 114 −6 Schizosaccharo- D89103 (sr:schizosaccharomyces pombe myces pombe (strain:pr745) cdna to mrna) (de:schizosaccharomyces pombe mrna, partial cds, clone: sy 0143.) (nt:unnamed protein product) 1275457_c2_948 7419 23990 1428 475 446 −41 Klebsiella Contig364A GTC ORF with score 2623 to: (ai:110770) pneumoniae (or:Escherichia coli) (gtcfc:14.1) (keggfc:14.2) (rileyfc:5.7.0) (db:gtc-escherichia coli) 31896006_c2_952 7420 23991 735 244 136 −6 Araneus U47855 (de:araneus diadematus fibroin-3 (adf-3) diadematus mrna, partial cds.) 34235 133_c2_955 7421 23992 1335 444 148 −7 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 13020806_c2_959 7422 23993 321 106 102 −4 Saccharomyces P32323 (sr:,baker's yeast) (de:a-agglutinin cerevisiae attachment subunit precursor) 5181916_c2_962 7423 23994 531 176 162 −12 Klebsiella Contig549A GTC ORF with score 162 to: pneumoniae (ai:7000781667) (or:Pseudomonas aeruginosa) 25792151_c2_967 7424 23995 219 72 14552076_c2_968 7425 23996 1719 572 132 −4 mice|C57BL/ U76716 (sr:house mouse) (de:mus musculus 6xCBA/CaJ voltage-sensitive calcium channel alpha 1a hybrid (ccha1a)mrna, complete cds.) (nt:ion channel) 31900955_c2_969 7426 23997 444 147 95 −2 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 35432017_c2_971 7427 23998 1113 370 119 −3 Homo sapiens P53420 (sr:,human) (de:collagen alpha 4(iv) chain precursor) 16538543_c2_973 7428 23999 783 260 129 −6 Caenorhabditis Z71178 (de:caenorhabditis elegans cosmid b0024, elegans complete sequence.) (nt:similar to collagen) 12788317_c2_975 7429 24000 1113 370 124 −4 Rattus norvegicus U49056 (sr:norway rat) (de:rattus norvegicus ctd- binding sr-like protein ra1 mrna, complete cds.) (nt:cid-binding sr-like protein) 6509826_c2_983 7430 24001 1392 463 13958391_c2_987 7431 24002 780 259 296 −26 Enterobacter CONTIG400 GTC ORF with score 296 to: cloacae (ai:7000781692) (or:Pseudomonas aeruginosa) 15907657_c2_991 7432 24003 987 328 191 −12 Homo sapiens X15332 (sr:human) (de:human co13a1 mrna for pro alpha-1(iii) collagen.) 11109632_c2_993 7433 24004 321 106 196 −15 Escherichia coli P08374 (ec:2.7.7.6) (de:omega chain) (rna polymerase omega subunit)) 34504205_c2_994 7434 24005 378 125 107 −4 Saccharomyces P08640 (sr:,baker's yeast) (ec:3.2.1.3) cerevisiae (de:glucosidase) (1,4-alpha-d-glucan glucohydrolase)) 12586655_c2_998 7435 24006 468 155 506 −48 Azotobacter B44514 (cl:hypothetical protein hi0719) vinelandii 10008533_c2_999 7436 24007 786 261 26253293_c2_1000 7437 24008 1521 506 138 −5 no gb taxonomy U93872 (sr:kaposi's sarcoma-associated match herpesvirus - human herpesvirus 8) (de:kaposi's sarcoma- associated herpesvirus glycoprotein m, dna replication protein, glycoprotein, dna replication protein, fliceinhibitory protein and y-cyclin genes. . . . 33869091_c2_1002 7438 24009 2094 697 218 −14 blue mussel AF015539 (sr:blue mussel) (de:mytilus edulis precollagen p (precol-p) mrna, complete cds.) 21523517_c2_1003 7439 24010 966 321 174 −13 Klebsiella Contig542A GTC ORF with score 174 to: pneumoniae (ai:7000781708) (or:Pseudomonas aeruginosa) 35239667_c2_1004 7440 24011 771 256 4431306_c2_1009 7441 24012 1326 441 145 −9 Klebsiella Contig531A GTC ORF with score 145 to: pneumoniae (ai:7000781714) (or:Pseudomonas aeruginosa) 17079207_c2_1024 7442 24013 630 209 172 −13 Escherichia coli P26602 (ec:4.—.—.—) (de:chorismate--pyruvate lyase,) 36126342_c2_1026 7443 24014 369 122 95 −5 Enterobacter CONTIG477 GTC ORF with score 95 to: cloacae (ai:7000781731) (or:Pseudomonas aeruginosa) 35802031_c2_1027 7444 24015 792 263 1114 −113 Pseudomonas P23620 (de:phosphate regulon transcriptional aeruginosa regulatory protein phob) 31723906_c2_1028 7445 24016 906 301 526 −50 Vibrio cholerae AF043352 (de:vibrio cholerae response regulator homolog phob (phob) and histidine protein kinase phor (phor) genes, complete cds.) 36036441_c2_1029 7446 24017 564 187 96 −3 Aspergillus Contig1817 GTC ORF with score 143 to: (gn:wsp1+) fumigatus (fn:actin patch assembly and localization) (sr:fission yeast) (de:schizosaccharomyces pombe wiskott-aldrich syndrome protein homolog(wsp1+) gene, complete cds, and bef3/beta-nac gene, partial sequence.) (nt:wasp 5160413_c2_1040 7447 24018 2490 829 36067516_c2_1046 7448 24019 240 79 167 −13 Klebsiella Contig229A GTC ORF with score 167 to: pneumoniae (ai:7000781751) (or:Pseudomonas aeruginosa) 9815667_c2_1050 7449 24020 243 80 22539801_c2_1056 7450 24021 1722 573 249 −21 Klebsiella Contig547A GTC ORF with score 398 to: pneumoniae (ai:7000840849) (or:Enterobacter cloacae) 6769800_c2_1061 7451 24022 486 161 9777290_c2_1070 7452 24023 1212 403 107 −2 Actinomyccs A49227 viscosus 31929066_c3_1078 7453 24024 576 191 137 −8 Araneus U47856 (de:araneus diadematus fibroin-4 mrna, diadematus partial cds.) 21532001_c3_1079 7454 24025 1194 397 152 −8 Caenorhabditis AF000198 (sr:caenorhabditis elegans strain=bristol elegans n2) (de:caenorhabditis elegans cosmid t2812.) (nt:similar to cuticular collagen) 14166705_c3_1080 7455 24026 915 304 592 −57 Escherichia coli P21866 (de:kdp operon transcription regulatory protein kdpe) 22788541_c3_1081 7456 24027 1029 342 978 −98 Escherichia coli P77470 (de:hypothetical 33.5 kd protein in uxab-marr intergenic region) 12364537_c3_1082 7457 24028 741 246 175 −12 Sus scrofa S55316 (sr:, domestic pig) domestica 12583156_c3_1084 7458 24029 801 266 91 −4 longfin squid S56117 (sr:, longfin squid) 22704826_c3_1085 7459 24030 1536 511 797 −79 Escherichia coli P33667 (de:hypothetical 41.1 kd protein in rhsd-gcl intergenic region) 16146028_c3_1091 7460 24031 1116 371 123 −5 Saimiriine Q01042 (sr:11,) (de:immediate-early protein) herpesvirus 2 4426025_c3_1093 7461 24032 906 301 518 −50 Sphingomonas P50197 (sr:,sphingomonas paucimobilis) paucimobilis (ec:1.1.—.—) (de:(2,5-ddol dehydrogenase)) 22301075_c3_1098 7462 24033 2484 827 657 −64 Pyrococcus AP000001 (sr:pyrococcus horikoshii (str:ot3) dna) horikoshii (de:pyrococcus horikoshii ot3 genomic dna, 1-287000 nt. position (1/7).) (nt:similar to:ss56khfr17 percent ident: 50.886) 35601026_c3_1106 7463 24034 1122 373 91 −1 Petunia axillaris P09789 (sr:,petunia) (de:glycine-rich cell wall X Petunia structural protein 1 precursor) integrifolia 15741681_c3_1110 7464 24035 612 203 128 −6 Enterobacter CONTIG370 GTC ORF with score 322 to: cloacae (ai:7000807782) (or:Pseudomonas aeruginosa) 29533433_c3_1114 7465 24036 1218 405 118 −5 Klebsiella Contig534A GTC ORF with score 397 to: pneumoniae (ai:7000828797) (or:Enterobacter cloacae) 4041281_c3_1117 7466 24037 417 138 124 −7 bovine Z84818 (de:bovine herpesvirus type 4 gene herpesvirus type 4 encoding gp80.) BVH-4 36042331_c3_1118 7467 24038 2898 965 1103 −112 Yersinia P30528 (ec:4.6.1.1) (de:cyclase)) intermedia 13789508_c3_1126 7468 24039 966 321 1205 −122 Pseudomonas Y12268 (de:p.fluorescens pc11233 dna fragment.) fluorescens 12978968_c3_1127 7469 24040 732 243 1160 −118 Pseudomonas S61401 aeruginosa 12360751_c3_1129 7470 24041 1254 417 154 −7 Alphaherpesvirus S04713 (cl:herpesvirus immediate-early protein pseudorabies ie 175) virus PRV 31462908_c3_1131 7471 24042 909 302 136 −6 Trypanosoma A44937 (cl:kinetoplast-associated protein) curzi 34260406_c3_1132 7472 24043 T488 495 457 −43 Bacillus B69780 subtilis/Bacillus globigii 12989541_c3_1139 7473 24044 1551 516 1312 −134 Haemophilus P45049 (de:hypothetical protein hi1117) influenzae 30335051_c3_1140 7474 24045 2124 707 214 −17 Klebsiella Contig442A GTC ORF with score 248 to: pneumoniae (ai:7000769216) (or:Pseudomonas aeruginosa) 31882257_c3_1145 7475 24046 708 235 110 −3 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 9870656_c3_1146 7476 24047 1677 558 249 −21 Enterobacter CONTIG463 GTC ORF with score 1613 to: cloacae (ai:750765603) (or:Klebsiella pneumoniae) 12213387_c3_1147 7477 24048 2106 701 120 −4 Klebsiella Contig560A GTC ORF with score 243 to: (ai:212909) pneumoniae (or:Azospirillum brasilense) (de:a.brasilense carr gene.) 13130137_c3_1152 7478 24049 1695 564 34244591_c3_1156 7479 24050 444 147 129 −7 mice|C57BL/ AF062655 (sr:house mouse) (de:mus musculus 6xCBA/CaJ plenty-of-prolines-101 mrna, complete hybrid cds.) (nt:binds to several sh3 domain containing proteins) 29938580_c3_1160 7480 24051 2415 804 13011457_c3_1161 7481 24052 909 302 475 −45 Escherichia coli P19494 (sr:,aerobacter aerogenes) (de:leucine- responsive regulatory protein) 14258582_c3_1162 7482 24053 1455 484 963 −97 Escherichia coli P37906 (ec:1.—.—.—) (de:probable oxidoreductase ordl,) 33792701_c3_1169 7483 24054 1809 602 210 −16 Azospirillum X70360 (de:a.brasilense carr gene.) brasilense 6769816_c3_1170 7484 24055 1749 582 203 −15 Streptomyces AL023496 (de:streptomyces coelicolor cosmid 1a6.) coelicolor (nt:sc1a6.22, unknown, : 135 aa) 9974018_c3_1172 7485 24056 1668 555 1216 −124 Escherichia coli P23847 (de:protein) (dbp)) 4010918_c3_1176 7486 24057 1218 405 1072 −108 Escherichia coli P24285 (de:dna/pantothenate metabolism flavoprotein) 15829003_c3_1177 7487 24058 3099 1032 2378 −247 Pseudomonas A40013 (ec:5.4.2.8) aeruginosa 36036416_c3_1178 7488 24059 2082 693 212 −14 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 15661561_c3_1179 7489 24060 1077 358 239 −19 Acinetobacter CONTIGI97 GTC ORF with score 461 to: baumannii C (ai:7000810327) (or:Pseudomonas aeruginosa) 2195767_c3_1185 7490 24061 498 165 360 −33 Ralstonia 139564 eutropha 16125658_c3_1187 7491 24062 405 134 192 −15 Klebsiella Contig295A GTC ORF with score 192 to: pneumoniae (ai:7000781892) (or:Pseudomonas aeruginosa) 10160041_c3_1190 7492 24063 807 268 421 −40 Enterobacter CONTIG400 GTC ORF with score 729 to: cloacae (ai:7501732464) (or:Klebsiella pneumoniae) 31772717_c3_1191 7493 24064 999 332 670 −66 Haemophilus P44726 (de:hypothetical protein hi0467) influenzae 16307281_c3_1192 7494 24065 1086 361 111 −3 Beta vulgaris S51939 (sr:, bcet) (ec:3.2.1.14) 32203543_c3_1195 7495 24066 1347 448 91 −3 longfin squid S56117 (sr:, longfin squid) 14572958_c3_1197 7496 24067 405 134 113 −5 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 24862905_c3_1201 7497 24068 411 136 99 −3 Rattus norvegicus Q62925 (sr:,rat) (cc:2.7.1.—) (de:mapk/erk kinase kinase 1, (mek kinase 1) (mekk 1)) 14879183_c3_1202 7498 24069 3012 1003 2040 −211 Escherichia coli P24230 (ec:3.6.1.—) (de:atp-dependent dna helicase recg,) 16134407_c3_1203 7499 24070 927 308 30603202_c3_1206 7500 24071 312 103 110 −7 Klebsiella Contig531A GTC ORF with score 110 to: pneumoniae (ai:7000781911) (or:Pseudomonas aeruginosa) 35835150_c3_1210 7501 24072 429 142 108 −5 Caenorhabditis AF067607 (de:caenorhabditis elegans cosmid c18h7.) elegans (nt:similar to cuticular collagen; c18h7.3) 15910203_c3_1212 7502 24073 561 186 124 −5 mice|C57BL AF062655 (sr:house mouse) (de:mus musculus 5xCBA/CaJ plenty-of-prolines-101 mrna, complete hybrids cds.) (nt:binds to several sh3 domain containing proteins) 1291706_c3_1213 7503 24074 273 90 97 −5 common tobacco PQ047S (sr:, common tobacco) 16510432_c3_1216 7504 24075 753 250 116 −4 Homo sapiens U94836 (sr:human) (de:human euprot 213-21 mrna, complete cds.) 16525928_c3_1217 7505 24076 969 322 141 −7 zebrafish U87758 (sr:zebrafish) (de:danio rerio znr-1 mrna, complete cds.) (nt:zebrafish nodal related 1 protein; similar to) 35286407_c3_1222 7506 24077 606 201 350 −32 Shigella P45609 (ec:2.7.3.—) (de:phosphate regulon sensor dysenteriae protein phor,) 3229553_c3_1224 7507 24078 657 218 112 −3 Homo sapiens M60494 (sr:human placenta dna, clone g-lambda- hf5) (de:human profilaggrin gene, 3′ end.) (nt:potential; putative) 16663886_c3_1228 7508 24079 1617 538 228 −16 Klebsiella Contig516A GTC ORF with score 124 to: pneumoniae (de:mycobacterium smegmatis iron uptake genes, fxba (fxba) gene, partial cds; and fxta (fxta), fxtb (fxtb), fxbb (fxbb), fxbc (fxbc), fxtc (fxtc), fxtd (fxtd), fxte (fxte), and fxtf (fxt)genes, complete cds.) (nt:similar to . . . 22478936_c3_1239 7509 24080 312 103 281 −25 Enterococcus CONTIG534 GTC ORF with score 422 to: faecalis (ai:7000736726) (or:Enterococcus faecium) 12281402_c3_1242 7510 24081 192 63 128 −9 Streptococcus CONTIG003 GTC ORF with score 128 to: pneumoniae D (ai:7000781947) (or:Pseudomonas aeruginosa) 964027_c3_1244 7511 24082 246 81 312 −28 Acinetobacter CONTIG229 GTC ORF with score 312 to: baumannii C (ai:7000781949) (or:Pseudomonas aeruginosa) 24728843_c3_1256 7512 24083 1554 517 22917708_c3_1258 7513 24084 1692 563 727 −72 Cyanobacterium S76584 (sr:pcc 6803,,pcc 6893) (sr:pcc 6803,) synechocystis 32676005_f1_6 7514 24085 621 206 134 −7 equine D88685 (sr:equine herpesvirus 1 (strain:hh1) dna) herpesvirus (de:equine herpesvirus 1 dna for tegument type 1 EVH-1 protein, partial cds.) (nt:kpn i subfragment of orf24) 17052280_f1_9 7515 24086 1155 384 123 −5 Arabidopsis AC000098 (sr:thale cress) (de:arabidopsis thaliana thaliana chromosome 1 yac yup8h12 complete sequence.) (nt:est gblatts1136 comes from this gene.) 24648266_f1_12 7516 24087 1686 561 36041693_f1_13 7517 24088 819 272 218 −18 Escherichia coli P45808 (de:hypothetical 14.8 kd protein in pric-apt intergenic region) 24689587_f1_15 7518 24089 402 133 97 −3 Herpes simplex AF015297 (de:human herpesvirus 6 (strain virus (type 6/ uganda-1102) ie2hom mrna, complete strain cds.) (nt:similar to the immediate-early 2 Uganda-1102) protein of human) 12947167_f1_18 7519 24090 975 324 249 −21 Klebsiella Contig348A GTC ORF with score 357 to: pneumoniae (ai:7000770786) (or:Pseudomonas aeruginosa) 11180380_f1_21 7520 24091 1386 461 180 −13 Enterobacter CONTIG489 GTC ORF with score 277 to: cloacae (ai:7501785540) (or:Klebsiella pneumoniae) 34400632_f1_22 7521 24092 744 247 3147577_f1_23 7522 24093 1953 650 332 −27 Acetobacter AF052517 (fn:cleaves a single phosphodiester bond xylinum in the) (de:acetobacter xylinus cdg1 operon, complete sequence.) (nt:pdea1; ca2+-sensitive phosphodiesterase a; requires) 10808167_f1_30 7523 24094 453 150 112 −5 Brassica napus U59446 (sr:rape) (de:brassica napus myrosinase- binding protein related protein mrna, partial cds.) (nt:divergently related to myrosinase binding protein;) 31900211_f1_37 7524 24095 2733 910 127 −7 Enterobacter CONTIG437 GTC ORF with score 127 to: cloacae (ai:7000782004) (or:Pseudomonas aeruginosa) 3222887_f1_42 7525 24096 885 294 174 −10 Microbacterium X79027 (de:m.ammoniaphilum genes mamir and ammoniaphilum mamim.) 32438512_f1_43 7526 24097 471 156 26816276_f1_44 7527 24098 1530 509 762 −75 Streptomyces AL031124 (de:streptomyces coelicolor cosmid 1c2.) coelicolor (nt:sc 1c2.05c, possible transmembrane transport) 22558518_f1_45 7528 24099 1485 494 354 −31 Bacillus H69670 (cl:proline carrier protein) subtilis/Bacillus globigii 24011532_f1_46 7529 24100 474 157 125 −7 Archacoglobus G69464 (cl:acetolactate synthase large fulgidus chain:thiamine pyrophosphate-binding domain homology) 13788540_f1_49 7530 24101 693 230 163 −10 Pseudomonas J05293 (ec:4.1.1.7) (de:pseudomonas putida putida benzoylformate decarboxylase (mdlc), s- mandelatedehydrogenase (mdlb), and mandelate racemase (mdla) genes, complete cds.) 31774156_f1_50 7531 24102 2169 722 226 −15 Homo sapiens AB002322 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:human mrna for kiaa0324 gene, partial cds.) 34070381_f1_52 7532 24103 885 294 240 −20 Klebsiella Contig486A GTC ORF with score 308 to: pneumoniae (ai:7000838385) (or:Enterobacter cloacae) 30208531_f1_54 7533 24104 1947 648 515 −50 Klebsiella Contig458A GTC ORF with score 515 to: pneumoniae (ai:7000782021) (or:Pseudomonas aeruginosa) 26736533_f1_57 7534 24105 2451 816 341 −27 Escherichia coli P77338 (de:aefa protein) 2447637_f1_58 7535 24106 972 323 243 −20 Bacillus P39587 (de:hypothetical 44.4 kd protein in subtilis/Bacillus epr-galk intergenic region) globigii 25995431_f1_63 7536 24107 1254 417 16033341_f1_66 7537 24108 471 156 17066668_f1_67 7538 24109 2718 905 113 −4 Aspergillus Contig1423 GTC ORF with score 289 to: fumigatus (ai:7000792986) (or:Pseudomonas aeruginosa) 521008_f1_69 7539 24110 954 317 355 −32 Pseudomonas AF087482 (de:pseudomonas aeruginosa clcc and aeruginosa ohbh genes, lys-r type regulatory protein (clcr), chlorocatechol-1,2-dioxygenase (clca), chloromuconate cycloisomerase (clcb), dienelactone hydrolase (clcd), malcylacetate reductase (clce) transposas . . . 32714691_f1_72 7540 24111 861 286 121 −4 Nephila clavipes A44112 3255417_f1_73 7541 24112 477 158 100 −6 Klebsiella Contig470A GTC ORF with score 100 to: pneumoniae (ai:7000782040) (or:Pseudomonas aeruginosa) 31345217_f1_80 7542 24113 552 183 107 −6 Klebsiella Contig559A GTC ORF with score 131 to: pneumoniae (ai:7000707509) (or:Mytilus edulis) (sr:blue mussel) (de:mytilus edulis precollagen d (precol-d) mrna, complete cds.) 268 6530_f1_81 7543 24114 2724 907 128 −4 Salmonella U43350 (sr:salmonella enterica strain=s2978) entericia (de:salmonella enterica isocitrate lyasc (acea) gene, partial cds, isocitrate dehydrogenase kinase/phosphatase (acek) gene, complete cds.) 21881451_f1_86 7544 24115 591 196 302 −28 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 12130325_f1_93 7545 24116 1008 335 320 −29 Enterobacter CONTIG223 GTC ORF with score 320 to: cloacae (ai:7000782060) (or:Pseudomonas aeruginosa) 21658316_f1_98 7546 24117 1251 416 1421 −145 Chromatium AF034104 (de:chromatium vinosum pet operon fe-s vinosum protein (peta), cytochrome b(petb), and cytochrome c1 (petc) genes, complete cds.) 13128756_fl_99 7547 24118 837 278 555 −53 Escherichia coli P05838 (de:stringent starvation protein a) 29926568_f1_100 7548 24119 666 221 183 −14 Enterobacter CONTIG96 GTC ORF with score 509 to: cloacae (ai:7501735549) (or:Klebsiella pneumoniae) 26073586_f1_102 7549 24120 1740 579 845 −84 Escherichia coli P45528 (de:hypothetical 31.3 kd protein in agai-mtr intergenic region (1286)) 35258292_f1_104 7550 24121 1011 336 849 −85 Escherichia coli P18595 (de:hypothetical 34.9 kd protein in frur-ftsl intergenic region (orfb)) 35754131_f1_109 7551 24122 1335 444 243 −20 Pseudomonas Q59650 (ec:6.3.2.13) (de:(ec 6.3.2.13) (udp-n- aeruginosa acetylmuramyl-tripeptide synthetase) (fragment)) 14938330_f1_111 7552 24123 360 119 98 −5 Aspergillus Contig8078 GTC ORF with score 219 to: (ai:175260) fumigatus (or:Volvox carteri) 12938505_f1_114 7553 24124 1173 390 728 −72 Escherichia coli P17443 (ec:2.4.1.—) (de:(ec 2.4.1.—)) 31899066_f1_116 7554 24125 1653 550 782 −78 Escherichia coli P07862 (ec:6.3.2.4) (de:synthetase)) 35353408_f1_117 7555 24126 867 288 314 −28 Escherichia coli P06136 (de:cell division protein ftsq) 15057878_f1_118 7556 24127 1089 362 1249 −127 Pseudomonas AF038380 (de:pseudomonas putida cell division putida protein ftsa gene, complete cds.) (nt:cell division protein; similar to pseudomonas) 34649187_f1_120 7557 24128 1203 400 1949 −201 Pseudomonas P47204 (de:cell division protein ftsz) aeruginosa 4478403_f1_125 7558 24129 927 308 292 −27 Rickettsia AJ235269 Rickettsia prowazekii strain Madrid E, prowazekii complete genome. 16538252_f1_126 7559 24130 1803 600 112 −3 Beta vulgaris S51939 (sr:, beet)(ec:3.2.1.14) 31345436_f1_128 7560 24131 1905 634 1016 −102 Neisseria P38434 (ec:2.3.1.35:2.3.1.1) (de:acetyltransferase, gonorrhoeae (n-acetylglutamate synthase) (ags)) 4978812_f1_129 7561 24132 723 240 127 −6 Caenorhabditis Z66560 (de:caenorhabditis elegans cosmid d1053, elegans complete sequence.) (nt:similar to glutathione s-transferase) 10006890_f1_137 7562 24133 2241 746 110 −4 Aspergillus Contig845S GTC ORF with score 110 to: fumigatus (ai:7000782104) (or:Pseudomonas aeruginosa) 10972707_f1_138 7563 24134 1008 335 4322250_f1_139 7564 24135 1011 336 25417281_f1_155 7565 24136 741 246 779 −77 Pseudomonas Y09798 (de:p.fluorescens colr, cols and oril22 fluorescens genes.) (nt:function unknown) 34277308_f1_170 7566 24137 426 141 102 −6 Klebsiella Contig438A GTC ORF with score 115 to: pneumoniae (ai:7000772235) (or:Pseudomonas aeruginosa) 10058341_f1_174 7567 24 138 1224 407 114 −6 Vibrio cholorae AJ231113 (de:vibrio cholorae z54f gene.) 24738342_f1_175 7568 24139 1494 497 10987705_f1_176 7569 24140 996 331 1277305_f1_177 7570 24141 2001 666 254 −21 Enterobacter CONTIG463 GTC ORF with score 1613 to: (ai:7501765603) (or:Klebsiella pneumoniae) 36020430_f1_178 7571 24142 1176 391 407 −38 Klebsiella Contig396A GTC ORF with score 407 to: pneumoniae (ai:7000782145) (or:Pseudomonas aeruginosa) 1072705_f1_179 7572 24143 474 157 217 −18 Escherichia coli P24194 (de:chromosome initiation inhibitor (oric replication inhibitor)) 31895887_f1_181 7573 24144 1449 482 33213213_f1_185 7574 24145 519 172 282 −23 Escherichia coli P33650 (de:ferrous iron transport protein b) 26588158_f1_186 7575 24146 2094 697 2276 −236 Escherichia coli P33650 (de:ferrous iron transport protein b) 4431910_f1_189 7576 24147 669 222 124 −5 Boreogadus saida U43200 (de:boreogadus saida antifreeze glycopeptide afgp polyprotein precursorgene, complete cds.) (nt:cleavage of polyprotein at conserved spacers r or) 22755258_f1_192 7577 24148 519 172 111 −4 infectious bovine S61242 rhinotracheitis virus 35807881_f1_193 7578 24149 1074 357 200 −14 Aquifex aeolicus C70374 9869805_f1_200 7579 24150 1266 421 234 −19 Mycobacterium AL123456 (de:mycobacterium tuberculosis h37rv tuberculosis complete genome; segment 78/162.) (nt:rv1723, (mtcy04c12.08), len: 415. similar to) 36041631_f1_203 7580 24151 1041 346 103 −2 Epstein-Barr virus P03211 (sr:b95-8, human herpesvirus 4) (de:ebna-1 nuclear protein) 16116458_f1_206 7581 24152 366 121 91 −4 malaria parasite U72948 (sr:malaria parasite) (de:plasmodium falciparum merozoite surface protein 2 (msp-2) gene, partial cds.) (nt:allele: fc27) 30729155_f1_211 7582 24153 795 264 34507090_f1_215 7583 24154 585 194 172 −13 Homo sapiens S18946 (sr:, man) 31735828_f1_218 7584 24155 627 208 376 −47 Burkholderia U41162 (sr:burkholderia cepacia strain=17616) cepacia (de:burkholderia cepacia d-serine deaminase (dsd) gene, complete cds.) (nt:unidentified orf) 4145656_f1_227 7585 24156 1041 346 284 −25 Pseudomonas AF087482 (de:pseudomonas aeruginosa clcc and aeruginosa ohbh genes, lys-r type regulatory protein (clcr), chlorocatechol-1,2-dioxygenase (clca), chloromuconate cycloisomerase (clcb), dienelactone hydrolase (clcd), malcylacetate reductase (clce), transposas . . . 36042568_f2_236 7586 24157 1248 415 180 −11 eastern European U70651 (sr:eastern european house mouse) house mouse (de:mus musculus musculus sex determining protein (sry) gene, complete cds.) (nt:hmg box transcription factor) 15792640_f2_238 7587 24158 375 124 103 −5 common tobacco B48232 (sr:, common tobacco) 12769705_f2_241 7588 24159 2046 681 279 −24 Acinetobacter CONTIG165 GTC ORF with score 279 to: baumannii C (ai:7000782208) (or:Pseudomonas aeruginosa) 36058191_f2_243 7589 24160 408 135 102 −4 Homo sapiens AF048977 (fn:splicing factor) (sr:human) (de:homo sapiens ser/arg-related nuclear matrix protein (srm160) mrna, complete cds.) (nt:160 kda) 31744031_f2_244 7590 24161 363 120 166 −13 Enterobacter CONTIG249 GTC ORF with score 234 to: cloacae (ai:7000785912) (or:Pseudomonas aeruginosa) 16145806_f2_245 7591 24162 3171 1056 115 −2 no gb taxonomy U52064 (de:kaposi's sarcoma-associated herpes- match like virus orf73 homolog gene, complete cds.) (nt:herpesvirus saimiri orf3 homolog) 21875181_f2_259 7592 24163 2739 912 99 −2 Drosophila M97196 (sr:drosophila melanogaster (strain oregon melanogaster r) (library: embl3) dna) (de:drosophila melanogaster dna-binding protein isoform i, complete cds, and isoforms ii and iii, 3′ end.) (nt:5′ end of isoform ii not yet determined 32444707_f2_261 7593 24164 825 274 91 −2 upland cotton L17308 (sr:gossypium hirsutum (strain coker 312) fiber cdna to mrna) (de:gossypium hirsutum proline-rich cell wall protein mrna, complete cds.) 32317041_f2_262 7594 24165 975 324 131 −5 Canadian hard P10388 (sr:,wheat) (de:glutenin, high molecular winter wheat weight subunit dx5 precursor) 17066542_f2_263 7595 24166 198 65 108 −6 Klebsiella Contig463A GTC ORF with score 111 to: pneumoniae (ai:7000782229) (or:Pseudomonas aeruginosa) 14166708_f2_264 7596 24167 534 177 100 −2 Homo sapiens AB011167 (sr:homo sapiens male brain cdna to mrna, clone_lib:pbluescriptii s) (de:homo sapiens mrna for kiaa0595 protein, partial cds.) 12369666_f2_266 7597 24168 741 246 25484438_f2_270 7598 24169 1437 478 134 −5 Homo sapiens AF031588 (fn:induces actin polymerization and redistribution) (sr:human) (de:homo sapiens wasp interacting protein (wip) mrna, partial cds.) (nt:similar to prpl-2, encoded by genbank accession) 6348293_f2_273 7599 24170 969 322 577 −56 Streptomyces P37819 (ec:3.5.3.11) (de:possible agmatinase, clavuligerus (agmatine ureohydrolase) (auh)) 16047542_f2_280 7600 24171 1182 393 164 −9 Saccharomyces P07342 (sr:,baker's yeast) (ec:4.1.3.18) cerevisiae (de:synthase) (als) (ahas)) 30744455_f2_282 7601 24172 1434 477 639 −62 Arabidopsis Z99708 (sr:thale cress) (de:arabidopsis thaliana thaliana dna chromosome 4, essa i ap2 contig fragmentno. 2.) (nt:strong similarity to aip2 protein, saccharomyces) 1250625_f2_289 7602 24173 1323 440 16895907_f2_293 7603 24174 1323 440 31902056_f2_295 7604 24175 357 118 96 −4 equine P28968 (sr:ab4p,ehv-1) (de:glycoprotein x herpesvirus type 1 precursor) EVH-1

SEQUENCE LISTING The patent contains a lengthy “Sequence Listing” section. A copy of the “Sequence Listing” is available in electronic form from the USPTO web site (http://seqdata.uspto.gov/sequence.html?DocID=06551795B1). An electronic copy of the “Sequence Listing” will also be available from the USPTO upon request and payment of the fee set forth in 37 CFR 1.19(b)(3). 

What is claimed is:
 1. An isolated nucleic acid comprising a nucleotide sequence encoding a P. aeruginosa polypeptide selected from the group consisting of SEQ ID NO: 17411, SEQ ID NO: 17456, SEQ ID NO: 18830, SEQ ID NO: 21016, SEQ ID NO: 21380, SEQ ID NO: 22234, SEQ ID NO: 24200, SEQ ID NO: 27183, SEQ ID NO: 27280, and SEQ ID NO:
 32329. 2. A recombinant expression vector comprising the nucleic acid of claim 1 operably linked to a transcription regulatory element.
 3. A cell comprising a recombinant expression vector of claim
 2. 4. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 3 under conditions that permit expression of the polypeptide.
 5. An isolated nucleic acid comprising a nucleotide sequence encoding a P. aeruginosa polypeptide, said nucleic acid selected from the group consisting of SEQ ID NO: 840, SEQ ID NO: 885, SEQ ID NO: 2259, SEQ ID NO: 4445, SEQ ID NO: 4809, SEQ ID NO: 5663, SEQ ID NO: 7629, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO:
 15758. 6. A recombinant expression vector comprising the nucleic acid of claim 5 operably linked to a transcription regulatory element.
 7. A cell comprising a recombinant expression vector of claim
 6. 8. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 7 under conditions that permit expression of the polypeptide.
 9. A probe comprising a nucleotide sequence of at least 30 nucleotides of a nucleotide sequence selected from the group consisting of SEQ ID NO: 4445, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO:
 15758. 10. An isolated nucleic acid or the complement thereof comprising a nucleotide sequence of at least 40 nucleotides in length selected from the group consisting of SEQ ID NO: 4445, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO: 15758, wherein the sequence is hybridizable under conditions of high stringency to a nucleic acid having a nucleotide sequence selected from the group consisting of SEQ ID NO: 4445, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO: 15758, or the complement thereof.
 11. An isolated nucleic acid comprising a nucleotide sequence encoding a P. aeruginosa polypeptide selected from the group consisting of SEQ ID NO: 17456, SEQ ID NO: 18830, SEQ ID NO: 21016, SEQ ID NO: 21380, SEQ ID NO: 22234, SEQ ID NO: 27183, SEQ ID NO: 27280, and SEQ ID NO:
 32329. 12. A recombinant expression vector comprising the nucleic acid of claim 11 operably linked to a transcription regulatory element.
 13. A cell comprising a recombinant expression vector of claim
 12. 14. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 13 under conditions that permit polypeptide expression.
 15. An isolated nucleic acid comprising a nucleotide sequence with at least 80% sequence identity to a nucleotide sequence selected from the group consisting of SEQ ID NO: 885, SEQ ID NO: 2259, SEQ ID NO: 4445, SEQ ID NO: 4809, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO: 15758, and wherein said isolated nucleic acid encodes a P. aeruginosa polypeptide selected from the group consisting of SEQ ID NO: 17456, SEQ ID NO: 18830, SEQ ID NO: 21016, SEQ ID NO: 21380, SEQ ID NO: 22234, SEQ ID NO: 27183, SEQ ID NO: 27280, and SEQ ID NO: 32329, respectively.
 16. A recombinant expression vector comprising the nucleic acid of claim 15 operably linked to a transcription regulatory element.
 17. A cell comprising a recombinant expression vector of claim
 16. 18. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 17 under conditions that permit polypeptide expression.
 19. An isolated nucleic acid comprising a nucleotide sequence with at least 90% sequence identity to a nucleotide sequence selected from the group consisting of SEQ ID NO: 885, SEQ ID NO: 2259, SEQ ID NO: 4445, SEQ ID NO: 4809, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO: 15758 and wherein said isolated nucleic acid encodes a P. aeruginosa polypeptide selected from the group consisting of SEQ ID NO: 17456, SEQ ID NO: 18830, SEQ ID NO: 21016, SEQ ID NO: 21380, SEQ ID NO: 22234, SEQ ID NO: 27183, SEQ ID NO: 27280, and SEQ ID NO:
 32329. 20. A recombinant expression vector comprising the nucleic acid of claim 19 operably linked to a transcription regulatory element.
 21. A cell comprising a recombinant expression vector of claim
 20. 22. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 21 under conditions that permit polypeptide expression.
 23. An isolated nucleic acid comprising a nucleotide sequence encoding a P. aeruginosa polypeptide, said nucleic acid selected from the group consisting of SEQ ID NO: 885, SEQ ID NO: 2259, SEQ ID NO: 4445, SEQ ID NO: 4809, SEQ ID NO: 5663, SEQ ID NO: 10612, SEQ ID NO: 10709, and SEQ ID NO:
 15758. 24. A recombinant expression vector comprising the nucleic acid of claim 23 operably linked to a transcription regulatory element.
 25. A cell comprising a recombinant expression vector of claim
 23. 26. A method for producing a P. aeruginosa polypeptide comprising culturing a cell of claim 25 under conditions that permit polypeptide expression. 